category subcategory ID Description GeneRatio BgRatio FoldEnrichment geneName zScore Genetic Information Processing Translation hsa03010 Ribosome 37/133 222/9376 11.749373433584 RPS26/RPS4Y1/RPL36A/RPL37A/RPL17/RPL37/RPS29/RPL4/RPL41/RPS25/RPL23A/RPL34/RPL38/RPS10/RPL21/RPS20/RPL23/RPSA/RPL31/RPS27/RPL13A/RPL22/RPL36/RPS16/MRPL23/RPL39/RPLP2/RPLP0/RPL7/RPL35A/RPL9/RPS28/RPL26/RPS11/RPL30/RPS17/MRPL39 19.4428159872727 Human Diseases Infectious disease: viral hsa05171 Coronavirus disease - COVID-19 36/133 238/9376 10.6632968977065 RPS26/RPS4Y1/RPL36A/RPL37A/RPL17/RPL37/RPS29/RPL4/RPL41/RPS25/RPL23A/RPL34/RPL38/RPS10/RPL21/RPS20/RPL23/RPSA/RPL31/RPS27/RPL13A/RPL22/RPL36/RPS16/JUN/RPL39/RPLP2/RPLP0/RPL7/RPL35A/RPL9/RPS28/RPL26/RPS11/RPL30/RPS17 18.113117606579 Metabolism Global and overview maps hsa01230 Biosynthesis of amino acids 7/133 75/9376 6.57964912280702 ALDOA/ENO1/PKM/TPI1/BCAT1/RPIA/PGK1 5.81939291254561 Metabolism Carbohydrate metabolism hsa00010 Glycolysis / Gluconeogenesis 6/133 67/9376 6.31309617326899 LDHA/ALDOA/ENO1/PKM/TPI1/PGK1 5.2352635025951 Human Diseases Infectious disease: bacterial hsa05100 Bacterial invasion of epithelial cells 6/133 78/9376 5.42278773857721 FN1/ACTG1/ARPC3/VCL/CAV2/ACTB 4.70493480063626 Cellular Processes Cellular community - eukaryotes hsa04530 Tight junction 8/133 170/9376 3.31747014595312 ACTG1/YBX3/ACTN1/JUN/PPP2R2B/CLDN19/ARPC3/ACTB 3.65770019761468 Cellular Processes Cell motility hsa04810 Regulation of actin cytoskeleton 9/133 232/9376 2.73476795436868 FN1/ACTG1/SCIN/ACTN1/PFN2/ENAH/ARPC3/VCL/ACTB 3.20938824009022 Metabolism Global and overview maps hsa01200 Carbon metabolism 6/133 116/9376 3.64635727249157 ALDOA/ENO1/PKM/TPI1/RPIA/PGK1 3.44014667248322 Organismal Systems Immune system hsa04670 Leukocyte transendothelial migration 6/133 116/9376 3.64635727249157 ACTG1/CD99/ACTN1/CLDN19/VCL/ACTB 3.44014667248322 Cellular Processes Cellular community - eukaryotes hsa04510 Focal adhesion 8/133 203/9376 2.77817696951739 FN1/ACTG1/FLNB/ACTN1/JUN/VCL/CAV2/ACTB 3.07236129590609 Metabolism Carbohydrate metabolism hsa00051 Fructose and mannose metabolism 3/133 35/9376 6.04253490870032 ALDOA/AKR1B1/TPI1 3.58501710182517 Human Diseases Infectious disease: bacterial hsa05135 Yersinia infection 6/133 138/9376 3.06505393919582 FN1/ACTG1/JUN/ARPC3/MAP2K3/ACTB 2.93148007263007 Human Diseases Cardiovascular disease hsa05418 Fluid shear stress and atherosclerosis 6/133 142/9376 2.97871439161283 ACTG1/GSTM3/CALM2/JUN/CAV2/ACTB 2.84995059721979 NA NA hsa04518 Integrin signaling 6/133 154/9376 2.74660677668196 FN1/ACTG1/FLNB/ACTN1/VCL/ACTB 2.62148830448864 Metabolism Amino acid metabolism hsa00330 Arginine and proline metabolism 3/133 50/9376 4.22977443609023 AOC1/CNDP2/P4HA1 2.74672051681056 Metabolism Amino acid metabolism hsa00340 Histidine metabolism 2/133 22/9376 6.40874914559125 AOC1/CNDP2 3.04659327708325 Metabolism Amino acid metabolism hsa00270 Cysteine and methionine metabolism 3/133 54/9376 3.91645781119465 LDHA/BCAT1/CDO1 2.57811930678375 Cellular Processes Cellular community - eukaryotes hsa04520 Adherens junction 4/133 93/9376 3.03209636995715 ACTG1/ACTN1/VCL/ACTB 2.36236272417004 Cellular Processes Cell motility hsa04820 Cytoskeleton in muscle cells 7/133 233/9376 2.1179128077705 FN1/ACTG1/TPM1/ENO1/TPM4/VCL/ACTB 2.07274804706413 Metabolism Metabolism of other amino acids hsa00480 Glutathione metabolism 3/133 59/9376 3.58455460685612 GPX3/PRDX6/GSTM3 2.38879374218663 Human Diseases Cardiovascular disease hsa05410 Hypertrophic cardiomyopathy 4/133 99/9376 2.84833295359611 ACTG1/TPM1/TPM4/ACTB 2.21768065294134 Human Diseases Infectious disease: parasitic hsa05146 Amoebiasis 4/133 103/9376 2.7377180816118 FN1/SERPINB9/ACTN1/VCL 2.12712388768465 Human Diseases Cardiovascular disease hsa05414 Dilated cardiomyopathy 4/133 105/9376 2.68557107053348 ACTG1/TPM1/TPM4/ACTB 2.08345157156746 Human Diseases Infectious disease: bacterial hsa05132 Salmonella infection 7/133 248/9376 1.98981324278438 ACTG1/PFN2/JUN/DYNLL2/ARPC3/MAP2K3/ACTB 1.89494350591556 Organismal Systems Endocrine system hsa04922 Glucagon signaling pathway 4/133 107/9376 2.63537348043005 LDHA/CALM2/PKM/PPP4C 2.04078559813822 Metabolism Global and overview maps hsa01240 Biosynthesis of cofactors 5/133 154/9376 2.2888389805683 BCAT1/RFK/MTHFD1L/RDH13/ALAD 1.9344229960835 Human Diseases Infectious disease: bacterial hsa05131 Shigellosis 7/133 253/9376 1.95048887039734 ACTG1/ACTN1/PFN2/JUN/ARPC3/VCL/ACTB 1.83841451908932 Environmental Information Processing Signal transduction hsa04066 HIF-1 signaling pathway 4/133 110/9376 2.5634996582365 LDHA/ALDOA/ENO1/PGK1 1.97857705079829 Metabolism Carbohydrate metabolism hsa00030 Pentose phosphate pathway 2/133 31/9376 4.54814455493573 ALDOA/RPIA 2.37354506241111 Human Diseases Cardiovascular disease hsa05416 Viral myocarditis 3/133 70/9376 3.02126745435016 ACTG1/HLA-E/ACTB 2.03608667299558 Environmental Information Processing Signal transduction hsa04015 Rap1 signaling pathway 6/133 212/9376 1.99517662079728 ACTG1/PFN2/CALM2/ENAH/MAP2K3/ACTB 1.7580472256948 NA NA hsa04382 Cornified envelope formation 6/133 217/9376 1.94920480925817 KRT19/S100A6/KRT8/COL17A1/PPP2R2B/CLDN19 1.69695665565184 Metabolism Glycan biosynthesis and metabolism hsa00512 Mucin type O-glycan biosynthesis 2/133 36/9376 3.91645781119465 GALNT6/GALNT7 2.10299622373231 Organismal Systems Digestive system hsa04971 Gastric acid secretion 3/133 76/9376 2.78274633953304 ACTG1/CALM2/ACTB 1.87180178641591 Organismal Systems Environmental adaptation hsa04714 Thermogenesis 6/133 235/9376 1.79990401535754 ACTG1/NDUFA7/MAP2K3/MT-CO3/ACTB/COX16 1.489635232863 NA NA hsa04519 Cadherin signaling 9/133 404/9376 1.57046080547904 KRT19/ACTG1/ACTN1/KRT8/ENAH/ARPC3/VCL/MAP2K3/ACTB 1.40597255455347 Organismal Systems Circulatory system hsa04260 Cardiac muscle contraction 3/133 87/9376 2.43090484832772 TPM1/TPM4/MT-CO3 1.60838821484863 Organismal Systems Excretory system hsa04962 Vasopressin-regulated water reabsorption 2/133 44/9376 3.20437457279563 ARHGDIB/DYNLL2 1.75804241267127 Cellular Processes Cell growth and death hsa04210 Apoptosis 4/133 137/9376 2.0582843971242 ACTG1/CTSH/JUN/ACTB 1.49677036315717 Organismal Systems Endocrine system hsa04915 Estrogen signaling pathway 4/133 139/9376 2.02866879428788 KRT19/CALM2/FKBP4/JUN 1.46562368843352 Cellular Processes Cell motility hsa04814 Motor proteins 5/133 194/9376 1.81691341756453 ACTG1/TPM1/DYNLL2/TPM4/ACTB 1.37915548884004 Metabolism Carbohydrate metabolism hsa00620 Pyruvate metabolism 2/133 47/9376 2.9998400255959 LDHA/PKM 1.64866197291931 Organismal Systems Endocrine system hsa04912 GnRH signaling pathway 3/133 93/9376 2.27407227746786 CALM2/JUN/MAP2K3 1.48114080645298 NA NA hsa03272 Virion - Hepatitis viruses 2/133 48/9376 2.93734335839599 DPP4/CLDN19 1.61412784823823 Human Diseases Neurodegenerative disease hsa05014 Amyotrophic lateral sclerosis 8/133 368/9376 1.53252696959791 GPX3/ACTG1/NDUFA7/HNRNPA1/PFN2/MAP2K3/MT-CO3/ACTB 1.25013326076469 Metabolism Glycan biosynthesis and metabolism hsa00514 Other types of O-glycan biosynthesis 2/133 49/9376 2.87739757557158 GALNT6/GALNT7 1.58047738709564 Human Diseases Infectious disease: bacterial hsa05130 Pathogenic Escherichia coli infection 5/133 200/9376 1.76240601503759 ACTG1/JUN/CLDN19/ARPC3/ACTB 1.30731303530606 Human Diseases Infectious disease: bacterial hsa05110 Vibrio cholerae infection 2/133 51/9376 2.76455845496093 ACTG1/ACTB 1.5156596881843 Human Diseases Cancer: overview hsa05205 Proteoglycans in cancer 5/133 204/9376 1.72784903435058 FN1/ACTG1/TIMP3/CAV2/ACTB 1.26075109202315 Organismal Systems Sensory system hsa04750 Inflammatory mediator regulation of TRP channels 3/133 99/9376 2.13624971519708 CYP2J2/CALM2/MAP2K3 1.3633036220017 Human Diseases Cancer: overview hsa05203 Viral carcinogenesis 5/133 205/9376 1.7194205024757 SCIN/ACTN1/PKM/JUN/HLA-E 1.249270188329 Organismal Systems Circulatory system hsa04261 Adrenergic signaling in cardiomyocytes 4/133 154/9376 1.83107118445464 TPM1/CALM2/PPP2R2B/TPM4 1.24735768767836 Organismal Systems Endocrine system hsa04921 Oxytocin signaling pathway 4/133 154/9376 1.83107118445464 ACTG1/CALM2/JUN/ACTB 1.24735768767836 Cellular Processes Cell growth and death hsa04218 Cellular senescence 4/133 157/9376 1.79608256309564 ZFP36L1/CALM2/HLA-E/MAP2K3 1.2066213692122 Human Diseases Endocrine and metabolic disease hsa04932 Non-alcoholic fatty liver disease 4/133 157/9376 1.79608256309564 NDUFA7/JUN/ADIPOR1/MT-CO3 1.2066213692122 Human Diseases Infectious disease: bacterial hsa05134 Legionellosis 2/133 56/9376 2.51772287862513 EEF1A1/EEF1G 1.36641782997047 Organismal Systems Immune system hsa04659 Th17 cell differentiation 3/133 109/9376 1.94026350279368 JUN/EBI3/GATA3 1.18439953582623 Metabolism Amino acid metabolism hsa00360 Phenylalanine metabolism 1/133 16/9376 4.40601503759398 MIF 1.63558684988578 Environmental Information Processing Signal transduction hsa04350 TGF-beta signaling pathway 3/133 110/9376 1.92262474367738 INHBA/ID3/TGIF1 1.167562867521 Metabolism Metabolism of other amino acids hsa00430 Taurine and hypotaurine metabolism 1/133 17/9376 4.1468376824414 CDO1 1.55771879959416 Environmental Information Processing Signal transduction hsa04668 TNF signaling pathway 3/133 119/9376 1.77721614961774 JUNB/JUN/MAP2K3 1.02349363726443 Human Diseases Immune disease hsa05321 Inflammatory bowel disease 2/133 66/9376 2.13624971519708 JUN/GATA3 1.11115820319293 Organismal Systems Nervous system hsa04722 Neurotrophin signaling pathway 3/133 120/9376 1.76240601503759 ARHGDIB/CALM2/JUN 1.00825467931529 Metabolism Glycan biosynthesis and metabolism hsa00541 Biosynthesis of various nucleotide sugars 1/133 20/9376 3.52481203007519 CYB5R1 1.35582589498293 Environmental Information Processing Signal transduction hsa04152 AMPK signaling pathway 3/133 122/9376 1.73351411315173 SCD/PPP2R2B/ADIPOR1 0.978202175184299 Organismal Systems Endocrine system hsa04935 Growth hormone synthesis, secretion and action 3/133 122/9376 1.73351411315173 CSH1/JUNB/MAP2K3 0.978202175184299 NA NA hsa04517 IgSF CAM signaling 6/133 299/9376 1.41464027962884 ACTG1/ACTN1/DYNLL2/ARPC3/VCL/ACTB 0.874059298493418 Human Diseases Substance dependence hsa05031 Amphetamine addiction 2/133 69/9376 2.04336929279721 CALM2/JUN 1.04342856422479 Metabolism Metabolism of cofactors and vitamins hsa00770 Pantothenate and CoA biosynthesis 1/133 21/9376 3.35696383816685 BCAT1 1.29701695396797 Human Diseases Cancer: overview hsa05230 Central carbon metabolism in cancer 2/133 71/9376 1.98580959440856 LDHA/PKM 1.00015891035861 Organismal Systems Endocrine system hsa03320 PPAR signaling pathway 2/133 76/9376 1.85516422635536 SCD/SLC27A6 0.897883165470539 Human Diseases Infectious disease: viral hsa05167 Kaposi sarcoma-associated herpesvirus infection 4/133 196/9376 1.43869878778579 CALM2/JUN/ZFP36/HLA-E 0.744522987949188 Human Diseases Infectious disease: bacterial hsa05133 Pertussis 2/133 78/9376 1.80759591285907 CALM2/JUN 0.859115639242636 Human Diseases Infectious disease: parasitic hsa05140 Leishmaniasis 2/133 78/9376 1.80759591285907 EEF1A1/JUN 0.859115639242636 Metabolism Lipid metabolism hsa01040 Biosynthesis of unsaturated fatty acids 1/133 27/9376 2.61097187412977 SCD 1.00552354076548 Organismal Systems Immune system hsa04612 Antigen processing and presentation 2/133 82/9376 1.7194205024757 HLA-E/LGMN 0.784862148199997 Metabolism Metabolism of cofactors and vitamins hsa00790 Folate biosynthesis 1/133 28/9376 2.51772287862513 AKR1B1 0.964755197245632 Cellular Processes Cellular community - eukaryotes hsa04550 Signaling pathways regulating pluripotency of stem cells 3/133 144/9376 1.46867167919799 INHBA/ID3/KLF4 0.679840512526275 Human Diseases Endocrine and metabolic disease hsa04936 Alcoholic liver disease 3/133 144/9376 1.46867167919799 SCD/ADIPOR1/MAP2K3 0.679840512526275 Organismal Systems Sensory system hsa04744 Phototransduction 1/133 29/9376 2.43090484832772 CALM2 0.925717800863743 Human Diseases Cardiovascular disease hsa05412 Arrhythmogenic right ventricular cardiomyopathy 2/133 86/9376 1.63944745584892 ACTG1/ACTB 0.71458058868881 Metabolism Lipid metabolism hsa00591 Linoleic acid metabolism 1/133 30/9376 2.34987468671679 CYP2J2 0.88827241319952 Organismal Systems Immune system hsa04610 Complement and coagulation cascades 2/133 88/9376 1.60218728639781 SERPINE2/CLU 0.680795689247319 Metabolism Metabolism of other amino acids hsa00410 beta-Alanine metabolism 1/133 31/9376 2.27407227746786 CNDP2 0.852295591827571 Human Diseases Infectious disease: viral hsa05170 Human immunodeficiency virus 1 infection 4/133 214/9376 1.31768674021502 CALM2/JUN/HLA-E/MAP2K3 0.563917813298895 Human Diseases Cancer: overview hsa05235 PD-L1 expression and PD-1 checkpoint pathway in cancer 2/133 90/9376 1.56658312447786 JUN/MAP2K3 0.647851594888082 Human Diseases Cardiovascular disease hsa05417 Lipid and atherosclerosis 4/133 216/9376 1.30548593706488 CYP2J2/CALM2/JUN/MAP2K3 0.544847977800703 Metabolism Carbohydrate metabolism hsa00052 Galactose metabolism 1/133 32/9376 2.20300751879699 AKR1B1 0.817677218860035 Metabolism Carbohydrate metabolism hsa00640 Propanoate metabolism 1/133 32/9376 2.20300751879699 LDHA 0.817677218860035 Cellular Processes Transport and catabolism hsa04136 Autophagy - other 1/133 32/9376 2.20300751879699 GABARAP 0.817677218860035 Metabolism Global and overview maps hsa01210 2-Oxocarboxylic acid metabolism 1/133 33/9376 2.13624971519708 BCAT1 0.784318691547356 Cellular Processes Transport and catabolism hsa04145 Phagosome 3/133 155/9376 1.36444336648072 ACTG1/HLA-E/ACTB 0.548797178564147 Organismal Systems Immune system hsa04658 Th1 and Th2 cell differentiation 2/133 93/9376 1.51604818497858 JUN/GATA3 0.599918888735921 Human Diseases Infectious disease: viral hsa05160 Hepatitis C 3/133 156/9376 1.3556969346443 EIF3E/PPP2R2B/CLDN19 0.537380549788403 Environmental Information Processing Signal transduction hsa04390 Hippo signaling pathway 3/133 157/9376 1.34706192232173 ACTG1/PPP2R2B/ACTB 0.526041332050823 Environmental Information Processing Signaling molecules and interaction hsa04514 Cell adhesion molecule (CAM) interaction 3/133 160/9376 1.3218045112782 CD99/CLDN19/HLA-E 0.492476904647095 Metabolism Carbohydrate metabolism hsa00040 Pentose and glucuronate interconversions 1/133 36/9376 1.95822890559733 AKR1B1 0.690958656150376 Human Diseases Cancer: overview hsa05208 Chemical carcinogenesis - reactive oxygen species 4/133 227/9376 1.24222450399126 NDUFA7/GSTM3/JUN/MT-CO3 0.443148386345001 Organismal Systems Immune system hsa04666 Fc gamma R-mediated phagocytosis 2/133 98/9376 1.43869878778579 SCIN/ARPC3 0.52366948817026 Metabolism Amino acid metabolism hsa00350 Tyrosine metabolism 1/133 37/9376 1.90530380004064 MIF 0.661835410687756 Human Diseases Endocrine and metabolic disease hsa04933 AGE-RAGE signaling pathway in diabetic complications 2/133 101/9376 1.39596516042582 FN1/JUN 0.479916504226121 Metabolism Metabolism of cofactors and vitamins hsa00670 One carbon pool by folate 1/133 39/9376 1.80759591285907 MTHFD1L 0.606216452294071 Human Diseases Immune disease hsa05330 Allograft rejection 1/133 39/9376 1.80759591285907 HLA-E 0.606216452294071 Organismal Systems Digestive system hsa04974 Protein digestion and absorption 2/133 103/9376 1.3688590408059 COL17A1/DPP4 0.451516782376414 Human Diseases Infectious disease: parasitic hsa05142 Chagas disease 2/133 103/9376 1.3688590408059 JUN/PPP2R2B 0.451516782376414 Human Diseases Cancer: specific types hsa05225 Hepatocellular carcinoma 3/133 170/9376 1.24405130473242 ACTG1/GSTM3/ACTB 0.385190077683075 Cellular Processes Transport and catabolism hsa04137 Mitophagy - animal 2/133 105/9376 1.34278553526674 JUN/GABARAP 0.423700355711519 Organismal Systems Immune system hsa04625 C-type lectin receptor signaling pathway 2/133 105/9376 1.34278553526674 CALM2/JUN 0.423700355711519 Human Diseases Cancer: specific types hsa05219 Bladder cancer 1/133 41/9376 1.7194205024757 DAPK1 0.553761246869919 Metabolism Amino acid metabolism hsa00380 Tryptophan metabolism 1/133 42/9376 1.67848191908342 AOC1 0.528608336176481 Cellular Processes Cell growth and death hsa04216 Ferroptosis 1/133 42/9376 1.67848191908342 PRNP 0.528608336176481 Organismal Systems Immune system hsa04620 Toll-like receptor signaling pathway 2/133 109/9376 1.29350900186245 JUN/MAP2K3 0.369717557401556 Human Diseases Endocrine and metabolic disease hsa04940 Type I diabetes mellitus 1/133 44/9376 1.60218728639781 HLA-E 0.48025902808167 Human Diseases Immune disease hsa05332 Graft-versus-host disease 1/133 45/9376 1.56658312447786 HLA-E 0.456994295938658 Cellular Processes Transport and catabolism hsa04142 Lysosome biogenesis 4/133 250/9376 1.12793984962406 CTSH/SLC29A1/LITAF/LGMN 0.24594646806093 Metabolism Metabolism of cofactors and vitamins hsa00860 Porphyrin metabolism 1/133 46/9376 1.53252696959791 ALAD 0.434294854059362 Organismal Systems Endocrine system hsa04928 Parathyroid hormone synthesis, secretion and action 2/133 115/9376 1.22602157567833 PDE4C/GATA3 0.292532995609684 Human Diseases Endocrine and metabolic disease hsa04930 Type II diabetes mellitus 1/133 47/9376 1.49992001279795 PKM 0.412132522628018 Genetic Information Processing Chromosome hsa03082 ATP-dependent chromatin remodeling 2/133 117/9376 1.20506394190605 ACTG1/ACTB 0.26773501471577 Metabolism Amino acid metabolism hsa00280 Valine, leucine and isoleucine degradation 1/133 48/9376 1.46867167919799 BCAT1 0.390481122406919 Organismal Systems Immune system hsa04621 NOD-like receptor signaling pathway 3/133 187/9376 1.13095573157493 GBP2/JUN/GABARAP 0.216978234302572 Human Diseases Substance dependence hsa05030 Cocaine addiction 1/133 49/9376 1.43869878778579 JUN 0.369316293396521 Metabolism Lipid metabolism hsa00565 Ether lipid metabolism 1/133 51/9376 1.38227922748047 LPCAT1 0.328357053342959 Organismal Systems Immune system hsa04660 T cell receptor signaling pathway 2/133 122/9376 1.15567607543449 JUN/PPP2R2B 0.207607015166824 Organismal Systems Endocrine system hsa04919 Thyroid hormone signaling pathway 2/133 122/9376 1.15567607543449 ACTG1/ACTB 0.207607015166824 Organismal Systems Endocrine system hsa04913 Ovarian steroidogenesis 1/133 52/9376 1.3556969346443 CYP2J2 0.308521649090162 Human Diseases Neurodegenerative disease hsa05022 Pathways of neurodegeneration - multiple diseases 7/133 480/9376 1.0280701754386 GPX3/NDUFA7/PRNP/CALM2/MAP2K3/MT-CO3/UBE2L6 0.0757309388208731 Human Diseases Neurodegenerative disease hsa05012 Parkinson disease 4/133 268/9376 1.05218269554483 NDUFA7/CALM2/MT-CO3/UBE2L6 0.103965052552254 Organismal Systems Immune system hsa04611 Platelet activation 2/133 126/9376 1.11898794605562 ACTG1/ACTB 0.161295539039175 Human Diseases Immune disease hsa05320 Autoimmune thyroid disease 1/133 54/9376 1.30548593706488 HLA-E 0.270046489023372 Human Diseases Neurodegenerative disease hsa05020 Prion disease 4/133 275/9376 1.0253998632946 NDUFA7/PRNP/CAV2/MT-CO3 0.0512811966705885 Metabolism Global and overview maps hsa01212 Fatty acid metabolism 1/133 57/9376 1.23677615090357 SCD 0.215077861863564 Human Diseases Infectious disease: viral hsa05169 Epstein-Barr virus infection 3/133 205/9376 1.03165230148542 JUN/HLA-E/MAP2K3 0.0549640669145005 Organismal Systems Nervous system hsa04728 Dopaminergic synapse 2/133 133/9376 1.06009384363164 CALM2/PPP2R2B 0.0837248366172345 Metabolism Energy metabolism hsa00190 Oxidative phosphorylation 2/133 138/9376 1.02168464639861 NDUFA7/MT-CO3 0.0307827837292693 Metabolism Amino acid metabolism hsa00310 Lysine degradation 1/133 63/9376 1.11898794605562 SMYD2 0.113666744931651 Metabolism Lipid metabolism hsa00590 Arachidonic acid metabolism 1/133 63/9376 1.11898794605562 CYP2J2 0.113666744931651 Human Diseases Cancer: overview hsa05207 Chemical carcinogenesis - receptor activation 3/133 217/9376 0.974602404629084 GSTM3/JUN/KLF4 -0.0454049727538896 Organismal Systems Development and regeneration hsa04380 Osteoclast differentiation 2/133 142/9376 0.992904797204278 JUNB/JUN -0.0102192502014303 Metabolism Lipid metabolism hsa00561 Glycerolipid metabolism 1/133 65/9376 1.08455754771544 AKR1B1 0.0820570456061249 Organismal Systems Endocrine system hsa04929 GnRH secretion 1/133 65/9376 1.08455754771544 KISS1 0.0820570456061249 Environmental Information Processing Signaling molecules and interaction hsa04060 Cytokine-cytokine receptor interaction 4/133 298/9376 0.946258263107433 CSH1/GDF15/INHBA/EBI3 -0.113091437237995 Organismal Systems Nervous system hsa04720 Long-term potentiation 1/133 67/9376 1.05218269554483 CALM2 0.051418260190236 Human Diseases Infectious disease: viral hsa05166 Human T-cell leukemia virus 1 infection 3/133 224/9376 0.944146079484425 JUN/ZFP36/HLA-E -0.101490326173277 Metabolism Metabolism of cofactors and vitamins hsa00830 Retinol metabolism 1/133 68/9376 1.03670942061035 RDH13 0.0364425519236569 Environmental Information Processing Signal transduction hsa04024 cAMP signaling pathway 3/133 226/9376 0.93579080444474 CALM2/JUN/PDE4C -0.117204931017521 Organismal Systems Immune system hsa04664 Fc epsilon RI signaling pathway 1/133 69/9376 1.02168464639861 MAP2K3 0.0216858782538625 Organismal Systems Endocrine system hsa04924 Renin secretion 1/133 69/9376 1.02168464639861 CALM2 0.0216858782538625 Organismal Systems Endocrine system hsa04920 Adipocytokine signaling pathway 1/133 70/9376 1.00708915145005 ADIPOR1 0.00714112660313043 Human Diseases Cancer: overview hsa05204 Chemical carcinogenesis - DNA adducts 1/133 70/9376 1.00708915145005 GSTM3 0.00714112660313043 Human Diseases Cancer: specific types hsa05211 Renal cell carcinoma 1/133 70/9376 1.00708915145005 JUN 0.00714112660313043 Human Diseases Infectious disease: bacterial hsa05120 Epithelial cell signaling in Helicobacter pylori infection 1/133 71/9376 0.992904797204278 JUN -0.0071984796427142 Metabolism Xenobiotics biodegradation and metabolism hsa00982 Drug metabolism - cytochrome P450 1/133 73/9376 0.965701926047997 GSTM3 -0.035287804130177 Human Diseases Drug resistance: antineoplastic hsa01524 Platinum drug resistance 1/133 75/9376 0.939949874686717 GSTM3 -0.0626303313979342 Organismal Systems Endocrine system hsa04918 Thyroid hormone synthesis 1/133 75/9376 0.939949874686717 GPX3 -0.0626303313979342 Human Diseases Cancer: specific types hsa05214 Glioma 1/133 76/9376 0.927582113177681 CALM2 -0.0760354554748305 Metabolism Carbohydrate metabolism hsa00562 Inositol phosphate metabolism 1/133 78/9376 0.903797956429535 TPI1 -0.102339151105771 Genetic Information Processing Folding, sorting and degradation hsa03018 RNA degradation 1/133 78/9376 0.903797956429535 ENO1 -0.102339151105771 Human Diseases Infectious disease: viral hsa05161 Hepatitis B 2/133 163/9376 0.864984547257715 JUN/MAP2K3 -0.208584352630103 Metabolism Xenobiotics biodegradation and metabolism hsa00980 Metabolism of xenobiotics by cytochrome P450 1/133 79/9376 0.892357475968402 GSTM3 -0.115247359818252 Metabolism Xenobiotics biodegradation and metabolism hsa00983 Drug metabolism - other enzymes 1/133 82/9376 0.859710251237851 GSTM3 -0.15305111990135 Cellular Processes Transport and catabolism hsa04144 Endocytosis 3/133 250/9376 0.845954887218045 HLA-E/ARPC3/CAV2 -0.296130185568426 Cellular Processes Transport and catabolism hsa04140 Autophagy - animal 2/133 169/9376 0.834275036704186 DAPK1/GABARAP -0.260781749414871 Human Diseases Infectious disease: viral hsa05165 Human papillomavirus infection 4/133 333/9376 0.846801688906952 FN1/PKM/PPP2R2B/HLA-E -0.341448186959804 Human Diseases Infectious disease: viral hsa05164 Influenza A 2/133 173/9376 0.814985440479812 ACTG1/ACTB -0.294624751207476 Environmental Information Processing Signal transduction hsa04012 ErbB signaling pathway 1/133 86/9376 0.819723727924462 JUN -0.201458186201303 Human Diseases Cancer: specific types hsa05210 Colorectal cancer 1/133 87/9376 0.810301616109239 JUN -0.21322776659979 Environmental Information Processing Signaling molecules and interaction hsa04512 ECM-receptor interaction 1/133 89/9376 0.792092591028132 FN1 -0.23639170268604 Organismal Systems Nervous system hsa04727 GABAergic synapse 1/133 89/9376 0.792092591028132 GABARAP -0.23639170268604 Organismal Systems Aging hsa04211 Longevity regulating pathway 1/133 90/9376 0.783291562238931 ADIPOR1 -0.247792249651974 Organismal Systems Immune system hsa04662 B cell receptor signaling pathway 1/133 91/9376 0.774683962653888 JUN -0.259075788698471 Human Diseases Substance dependence hsa05032 Morphine addiction 1/133 91/9376 0.774683962653888 PDE4C -0.259075788698471 Organismal Systems Digestive system hsa04970 Salivary secretion 1/133 93/9376 0.758024092489288 CALM2 -0.281303028981139 Human Diseases Cancer: specific types hsa05222 Small cell lung cancer 1/133 93/9376 0.758024092489288 FN1 -0.281303028981139 Organismal Systems Development and regeneration hsa04360 Axon guidance 2/133 184/9376 0.766263484798954 EFNB1/ENAH -0.384092167171346 Organismal Systems Immune system hsa04657 IL-17 signaling pathway 1/133 94/9376 0.749960006398976 JUN -0.292252076809485 Human Diseases Immune disease hsa05323 Rheumatoid arthritis 1/133 95/9376 0.742065690542145 JUN -0.303094818954121 Organismal Systems Environmental adaptation hsa04713 Circadian entrainment 1/133 97/9376 0.726765367025812 CALM2 -0.324471090230388 Environmental Information Processing Signal transduction hsa04070 Phosphatidylinositol signaling system 1/133 98/9376 0.719349393892895 CALM2 -0.335009266828753 Organismal Systems Endocrine system hsa04925 Aldosterone synthesis and secretion 1/133 98/9376 0.719349393892895 CALM2 -0.335009266828753 Human Diseases Substance dependence hsa05034 Alcoholism 2/133 191/9376 0.738180529858678 CALM2/SLC29A1 -0.438514567335811 Human Diseases Drug resistance: antineoplastic hsa01522 Endocrine resistance 1/133 99/9376 0.712083238399028 JUN -0.345450439877579 Human Diseases Infectious disease: bacterial hsa05150 Staphylococcus aureus infection 1/133 99/9376 0.712083238399028 KRT19 -0.345450439877579 Human Diseases Cancer: overview hsa05231 Choline metabolism in cancer 1/133 99/9376 0.712083238399028 JUN -0.345450439877579 Organismal Systems Endocrine system hsa04916 Melanogenesis 1/133 101/9376 0.697982580212908 CALM2 -0.366050245844213 Organismal Systems Immune system hsa04613 Neutrophil extracellular trap formation 2/133 195/9376 0.723038365143628 ACTG1/ACTB -0.468810044671002 Genetic Information Processing Translation hsa03015 mRNA surveillance pathway 1/133 103/9376 0.684429520402949 PPP2R2B -0.386286770277704 Metabolism Lipid metabolism hsa00564 Glycerophospholipid metabolism 1/133 104/9376 0.677848467322152 LPCAT1 -0.39627360174647 Environmental Information Processing Signal transduction hsa04064 NF-kappa B signaling pathway 1/133 105/9376 0.671392767633369 EDARADD -0.406175252216453 Genetic Information Processing Translation hsa03013 Nucleocytoplasmic transport 1/133 108/9376 0.652742968532442 EEF1A1 -0.435386436769533 Human Diseases Endocrine and metabolic disease hsa04931 Insulin resistance 1/133 109/9376 0.646754500931227 SLC27A6 -0.444964421023118 Human Diseases Cardiovascular disease hsa05415 Diabetic cardiomyopathy 2/133 205/9376 0.687768200990281 NDUFA7/MT-CO3 -0.54218899379275 Human Diseases Infectious disease: parasitic hsa05145 Toxoplasmosis 1/133 112/9376 0.629430719656283 MAP2K3 -0.473242929833139 Organismal Systems Nervous system hsa04726 Serotonergic synapse 1/133 115/9376 0.613010787839163 CYP2J2 -0.500868614698791 Human Diseases Neurodegenerative disease hsa05016 Huntington disease 3/133 308/9376 0.686651694170491 GPX3/NDUFA7/MT-CO3 -0.670736492761449 NA NA hsa04081 Hormone signaling 2/133 219/9376 0.643801284031998 CSH1/ADIPOR1 -0.639797858451935 Environmental Information Processing Signal transduction hsa04071 Sphingolipid signaling pathway 1/133 125/9376 0.56396992481203 PPP2R2B -0.588683812672736 Human Diseases Infectious disease: viral hsa05163 Human cytomegalovirus infection 2/133 227/9376 0.621112251995628 CALM2/HLA-E -0.693173033146516 Metabolism Nucleotide metabolism hsa00230 Purine metabolism 1/133 128/9376 0.550751879699248 PDE4C -0.613864226351408 Organismal Systems Endocrine system hsa04926 Relaxin signaling pathway 1/133 130/9376 0.542278773857721 JUN -0.630377591290852 Environmental Information Processing Signal transduction hsa04068 FoxO signaling pathway 1/133 133/9376 0.530046921815818 GABARAP -0.654755001692446 Organismal Systems Immune system hsa04650 Natural killer cell mediated cytotoxicity 1/133 133/9376 0.530046921815818 HLA-E -0.654755001692446 Organismal Systems Circulatory system hsa04270 Vascular smooth muscle contraction 1/133 134/9376 0.526091347772416 CALM2 -0.662779454121003 Human Diseases Infectious disease: viral hsa05162 Measles 1/133 136/9376 0.518354710305175 JUN -0.678681120440757 Cellular Processes Cell growth and death hsa04114 Oocyte meiosis 1/133 138/9376 0.510842323199303 CALM2 -0.694391538495931 Organismal Systems Endocrine system hsa04910 Insulin signaling pathway 1/133 138/9376 0.510842323199303 CALM2 -0.694391538495931 Environmental Information Processing Signal transduction hsa04371 Apelin signaling pathway 1/133 140/9376 0.503544575725027 CALM2 -0.709916545452497 Genetic Information Processing Folding, sorting and degradation hsa04120 Ubiquitin mediated proteolysis 1/133 142/9376 0.496452398602139 UBE2L6 -0.725261712056735 Human Diseases Immune disease hsa05322 Systemic lupus erythematosus 1/133 143/9376 0.492980703507019 ACTN1 -0.732868527179782 Human Diseases Cancer: specific types hsa05224 Breast cancer 1/133 148/9376 0.476325950010161 JUN -0.770270207330746 Organismal Systems Nervous system hsa04723 Retrograde endocannabinoid signaling 1/133 149/9376 0.473129131553716 NDUFA7 -0.777628273303536 Environmental Information Processing Signal transduction hsa04151 PI3K-Akt signaling pathway 3/133 362/9376 0.584222988410252 FN1/CSH1/PPP2R2B -0.967745062011321 Cellular Processes Transport and catabolism hsa04148 Efferocytosis 1/133 157/9376 0.449020640773909 SLC16A1 -0.835118742271936 Environmental Information Processing Signal transduction hsa04022 cGMP-PKG signaling pathway 1/133 166/9376 0.42467614820183 CALM2 -0.897101515788908 Environmental Information Processing Signal transduction hsa04630 JAK-STAT signaling pathway 1/133 168/9376 0.419620479770856 CSH1 -0.910519071535957 Human Diseases Neurodegenerative disease hsa05010 Alzheimer disease 3/133 388/9376 0.545074025269359 NDUFA7/CALM2/MT-CO3 -1.09781724191474 Environmental Information Processing Signal transduction hsa04310 Wnt signaling pathway 1/133 178/9376 0.396046295514066 JUN -0.975824977293868 Human Diseases Infectious disease: viral hsa05168 Herpes simplex virus 1 infection 1/133 180/9376 0.391645781119465 HLA-E -0.988549174112264 Human Diseases Infectious disease: bacterial hsa05152 Tuberculosis 1/133 181/9376 0.389481992273501 CALM2 -0.994871251006394 Environmental Information Processing Signal transduction hsa04010 MAPK signaling pathway 2/133 300/9376 0.469974937343358 JUN/MAP2K3 -1.11921822115441 Human Diseases Cancer: overview hsa05206 MicroRNAs in cancer 2/133 323/9376 0.436509229730673 TPM1/TIMP3 -1.23622291639423 Environmental Information Processing Signal transduction hsa04014 Ras signaling pathway 1/133 238/9376 0.296202691602957 CALM2 -1.31921471037644 Environmental Information Processing Signaling molecules and interaction hsa04080 Neuroactive ligand-receptor interaction 2/133 370/9376 0.381060760008128 CSH1/KISS1 -1.45709507471907 Genetic Information Processing Transcription hsa03040 Spliceosome 1/133 243/9376 0.290107986014419 HNRNPA1 -1.34491141809174 Environmental Information Processing Signal transduction hsa04020 Calcium signaling pathway 1/133 254/9376 0.277544254336629 CALM2 -1.40019349561252 Organismal Systems Sensory system hsa04740 Olfactory transduction 1/133 449/9376 0.157007217375287 CALM2 -2.19583266673644