category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	26/240	238/9376	4.26778711484594	RPS26/RPS10/RPL17/RPL23A/RPL36A/RPS16/RPS11/RPS20/RPL23/FOS/RPLP0/RPL26/RPS4Y1/RPL21/RPL41/RPL13A/RPL4/JUN/RPS27L/RPS8/RPS3A/ISG15/RPL9/RPS2/JAK1/RPL7	8.27617892552141
Genetic Information Processing	Translation	hsa03010	Ribosome	25/240	222/9376	4.3993993993994	RPS26/RPS10/RPL17/RPL23A/RPL36A/RPS16/RPS11/RPS20/RPL23/RPLP0/RPL26/RPS4Y1/RPL21/RPL41/RPL13A/RPL4/MRPL23/RPS27L/RPS8/RPS3A/RPL9/RPS2/MRPS6/MRPS17/RPL7	8.30780779033412
Cellular Processes	Cellular community - eukaryotes	hsa04530	Tight junction	19/240	170/9376	4.36627450980392	MYL6/CLDN4/MYH9/ACTG1/ARPC2/PPP2R2B/ACTN4/JUN/CLDN23/ACTN1/RAP1A/CLDN3/SYNPO/AMOTL2/YBX3/CLDN7/PRKCI/RAC1/CLDN19	7.17879774200947
Human Diseases	Cardiovascular disease	hsa05418	Fluid shear stress and atherosclerosis	15/240	142/9376	4.12676056338028	FOS/DUSP1/ACTG1/KLF2/JUN/PDGFA/CALM1/SUMO2/CAV2/HMOX1/GSTM3/SDC1/HSP90AA1/CALM2/RAC1	6.08495087478264
Organismal Systems	Immune system	hsa04670	Leukocyte transendothelial migration	13/240	116/9376	4.37816091954023	CD99/CLDN4/ACTG1/RAP1B/ACTN4/CLDN23/ACTN1/RAP1A/CLDN3/VCL/CLDN7/RAC1/CLDN19	5.93358336342859
NA	NA	hsa04382	Cornified envelope formation	18/240	217/9376	3.24055299539171	KRT19/S100A6/COL17A1/S100A10/KRT8/CLDN4/PRSS8/PPP2R2B/CLDN23/S100A13/CLDN3/PKP2/DSP/KRT18/CLDN7/S100A16/CLDN19/ITGA6	5.41220541767973
NA	NA	hsa03272	Virion - Hepatitis viruses	7/240	48/9376	5.69722222222222	CLDN4/CLDN23/DPP4/CLDN3/CLDN7/EPCAM/CLDN19	5.28786879154277
Human Diseases	Infectious disease: bacterial	hsa05132	Salmonella infection	17/240	248/9376	2.67795698924731	S100A10/FOS/AHNAK/ACTG1/ARPC2/ANXA2/TUBB6/JUN/RHOB/TNFRSF10B/PFN1/DYNLRB1/SKP1/HSP90AA1/DYNLL1/RAC1/RRAS	4.34042306604743
Cellular Processes	Cellular community - eukaryotes	hsa04510	Focal adhesion	15/240	203/9376	2.88669950738916	FN1/FLNB/ACTG1/CAPN2/RAP1B/ACTN4/JUN/PDGFA/ACTN1/RAP1A/ITGB6/VCL/CAV2/RAC1/ITGA6	4.40461822928825
Cellular Processes	Cell motility	hsa04820	Cytoskeleton in muscle cells	16/240	233/9376	2.6826895565093	FN1/TPM1/TPM4/MYH9/ACTG1/FHL2/ENO1/PDLIM3/ITGB6/VCL/PKP2/DSP/TPM3/SDC1/PDLIM2/ITGA6	4.21551669448588
Environmental Information Processing	Signal transduction	hsa04066	HIF-1 signaling pathway	10/240	110/9376	3.55151515151515	LDHA/TFRC/ALDOA/SERPINE1/ENO1/HMOX1/CDKN1A/EIF4EBP1/EGLN3/PGK1	4.36276238305205
Human Diseases	Infectious disease: bacterial	hsa05130	Pathogenic Escherichia coli infection	13/240	200/9376	2.53933333333333	FOS/CLDN4/MYH9/ACTG1/ARPC2/TUBB6/JUN/CLDN23/CLDN3/TNFRSF10B/CLDN7/RAC1/CLDN19	3.56643392955911
Metabolism	Glycan biosynthesis and metabolism	hsa00512	Mucin type O-glycan biosynthesis	5/240	36/9376	5.42592592592593	GALNT6/GALNT7/ST6GALNAC2/C1GALT1C1/GALNT18	4.31216298167238
Human Diseases	Infectious disease: viral	hsa05160	Hepatitis C	11/240	156/9376	2.75470085470085	CLDN4/PPP2R2B/CLDN23/YWHAZ/CLDN3/EIF3E/CDKN1A/CLDN7/SOCS3/JAK1/CLDN19	3.5818973846221
Metabolism	Global and overview maps	hsa01230	Biosynthesis of amino acids	7/240	75/9376	3.64622222222222	PKM/ALDOA/TPI1/TALDO1/ENO1/RPIA/PGK1	3.72911121151308
NA	NA	hsa04518	Integrin signaling	10/240	154/9376	2.53679653679654	FN1/FLNB/ACTG1/ACTN4/PDGFA/ACTN1/ITGB6/VCL/RAC1/ITGA6	3.11657360528398
Cellular Processes	Cell motility	hsa04810	Regulation of actin cytoskeleton	13/240	232/9376	2.18908045977012	FN1/MYH9/ACTG1/ARPC2/ACTN4/PDGFA/ACTN1/ITGB6/VCL/PFN1/RAC1/RRAS/ITGA6	2.97235268712235
Metabolism	Carbohydrate metabolism	hsa00010	Glycolysis / Gluconeogenesis	6/240	67/9376	3.49850746268657	LDHA/PKM/ALDOA/TPI1/ENO1/PGK1	3.32644043204709
Human Diseases	Substance dependence	hsa05031	Amphetamine addiction	6/240	69/9376	3.39710144927536	FOSB/FOS/JUN/CALM1/CREB5/CALM2	3.23906241338245
Human Diseases	Cancer: specific types	hsa05211	Renal cell carcinoma	6/240	70/9376	3.34857142857143	RAP1B/JUN/RAP1A/CDKN1A/EGLN3/RAC1	3.19657193904207
Cellular Processes	Cellular community - eukaryotes	hsa04520	Adherens junction	7/240	93/9376	2.9405017921147	ACTG1/RAP1B/ACTN4/ACTN1/RAP1A/VCL/RAC1	3.04806736323146
NA	NA	hsa04517	IgSF CAM signaling	15/240	299/9376	1.95986622073579	MYL6/MYH9/ACTG1/ARPC2/TUBB6/RAP1B/ACTN4/ACTN1/RAP1A/IL1RAP/VCL/SRGAP1/PRKCI/DYNLL1/RAC1	2.73393602963657
Organismal Systems	Development and regeneration	hsa04380	Osteoclast differentiation	9/240	142/9376	2.47605633802817	FOSB/FOS/JUN/FHL2/JUNB/FOSL1/SOCS3/JAK1/RAC1	2.87253536791541
Human Diseases	Infectious disease: viral	hsa05166	Human T-cell leukemia virus 1 infection	12/240	224/9376	2.09285714285714	FOS/JUN/B2M/ZFP36/FOSL1/CDKN1A/EGR2/CREB5/JAK1/EGR1/MSX1/ETS2	2.68313554214381
Human Diseases	Infectious disease: bacterial	hsa05100	Bacterial invasion of epithelial cells	6/240	78/9376	3.00512820512821	FN1/ACTG1/ARPC2/VCL/CAV2/RAC1	2.88209233270737
Human Diseases	Cancer: overview	hsa05205	Proteoglycans in cancer	11/240	204/9376	2.10653594771242	FN1/TIMP3/ACTG1/CAV2/CDKN1A/WNT7A/WNT6/SDC1/PLAU/RAC1/RRAS	2.58977361310163
Human Diseases	Cancer: overview	hsa05203	Viral carcinogenesis	11/240	205/9376	2.09626016260163	PKM/ACTN4/JUN/YWHAZ/ACTN1/CDKN1A/EGR2/CREB5/JAK1/EGR3/RAC1	2.57214489525836
Cellular Processes	Transport and catabolism	hsa04137	Mitophagy - animal	7/240	105/9376	2.60444444444444	JUN/UBC/BNIP3L/CCZ1/GABARAP/RRAS/BNIP3	2.6795956024964
Organismal Systems	Immune system	hsa04625	C-type lectin receptor signaling pathway	7/240	105/9376	2.60444444444444	PLK3/JUN/CALM1/EGR2/CALM2/EGR3/RRAS	2.6795956024964
Cellular Processes	Cell growth and death	hsa04218	Cellular senescence	9/240	157/9376	2.23949044585987	ZFP36L1/GADD45A/SERPINE1/CAPN2/CALM1/CDKN1A/EIF4EBP1/CALM2/RRAS	2.53842488033586
Environmental Information Processing	Signal transduction	hsa04015	Rap1 signaling pathway	11/240	212/9376	2.02704402515723	ACTG1/RAP1B/PDGFA/EFNA1/CALM1/RAP1A/PFN1/PRKCI/CALM2/RAC1/RRAS	2.45147610372493
Organismal Systems	Immune system	hsa04659	Th17 cell differentiation	7/240	109/9376	2.50886850152905	FOS/GATA3/JUN/EBI3/IL1RAP/HSP90AA1/JAK1	2.56807837356144
Cellular Processes	Cell growth and death	hsa04216	Ferroptosis	4/240	42/9376	3.72063492063492	FTH1/TFRC/PRNP/HMOX1	2.86400801263248
Cellular Processes	Cell growth and death	hsa04210	Apoptosis	8/240	137/9376	2.28126520681265	GADD45A/FOS/CTSV/ACTG1/CAPN2/JUN/CTSH/TNFRSF10B	2.44849965139933
Organismal Systems	Excretory system	hsa04962	Vasopressin-regulated water reabsorption	4/240	44/9376	3.55151515151515	ARHGDIB/CREB5/DYNLL1/RAB11A	2.74947856593547
Organismal Systems	Endocrine system	hsa04915	Estrogen signaling pathway	8/240	139/9376	2.2484412470024	KRT19/FOS/JUN/CALM1/KRT18/CREB5/HSP90AA1/CALM2	2.40338447090899
Organismal Systems	Endocrine system	hsa04928	Parathyroid hormone synthesis, secretion and action	7/240	115/9376	2.37797101449275	FOS/GATA3/PDE4C/CDKN1A/CREB5/NR4A2/EGR1	2.40975713034438
Metabolism	Global and overview maps	hsa01200	Carbon metabolism	7/240	116/9376	2.35747126436782	PKM/ALDOA/TPI1/TALDO1/ENO1/RPIA/PGK1	2.38433547200039
Human Diseases	Infectious disease: bacterial	hsa05131	Shigellosis	12/240	253/9376	1.85296442687747	ACTG1/CAPN2/ARPC2/ACTN4/JUN/UBC/ACTN1/VCL/PFN1/SKP1/RAC1/BNIP3	2.22913081722002
NA	NA	hsa04519	Cadherin signaling	17/240	404/9376	1.64389438943894	KRT19/KRT8/ACTG1/ARPC2/ACTN4/LIMA1/YWHAZ/ACTN1/VCL/PKP2/DSP/KRT18/AMOTL2/WNT7A/WNT6/RAC1/RRAS	2.14424252415881
Organismal Systems	Immune system	hsa04657	IL-17 signaling pathway	6/240	94/9376	2.4936170212766	FOSB/FOS/JUN/TNFAIP3/FOSL1/HSP90AA1	2.35882440557864
Organismal Systems	Nervous system	hsa04722	Neurotrophin signaling pathway	7/240	120/9376	2.27888888888889	ARHGDIB/RAP1B/JUN/CALM1/RAP1A/CALM2/RAC1	2.28520401196023
Metabolism	Glycan biosynthesis and metabolism	hsa00514	Other types of O-glycan biosynthesis	4/240	49/9376	3.1891156462585	GALNT6/GALNT7/C1GALT1C1/GALNT18	2.49005517437295
Metabolism	Amino acid metabolism	hsa00330	Arginine and proline metabolism	4/240	50/9376	3.12533333333333	AOC1/OAT/P4HA1/CNDP2	2.44217940153503
Human Diseases	Cancer: overview	hsa05231	Choline metabolism in cancer	6/240	99/9376	2.36767676767677	FOS/SLC44A2/JUN/PDGFA/EIF4EBP1/RAC1	2.21722875541497
Human Diseases	Cardiovascular disease	hsa05410	Hypertrophic cardiomyopathy	6/240	99/9376	2.36767676767677	TPM1/TPM4/ACTG1/ITGB6/TPM3/ITGA6	2.21722875541497
Metabolism	Carbohydrate metabolism	hsa00030	Pentose phosphate pathway	3/240	31/9376	3.78064516129032	ALDOA/TALDO1/RPIA	2.51333268809262
Environmental Information Processing	Signal transduction	hsa04010	MAPK signaling pathway	13/240	300/9376	1.69288888888889	GADD45A/FOS/DUSP1/NR4A1/RAP1B/JUN/DUSP5/PDGFA/EFNA1/RAP1A/IL1RAP/RAC1/RRAS	1.97692500430602
Human Diseases	Endocrine and metabolic disease	hsa04933	AGE-RAGE signaling pathway in diabetic complications	6/240	101/9376	2.32079207920792	FN1/SERPINE1/JUN/EGR1/RAC1/PIM1	2.16297448863518
Human Diseases	Cancer: specific types	hsa05214	Glioma	5/240	76/9376	2.57017543859649	GADD45A/PDGFA/CALM1/CDKN1A/CALM2	2.22754617387684
Environmental Information Processing	Signal transduction	hsa04151	PI3K-Akt signaling pathway	15/240	362/9376	1.61878453038674	FN1/CSH1/NR4A1/PPP2R2B/YWHAZ/PDGFA/EFNA1/ITGB6/CDKN1A/EIF4EBP1/CREB5/HSP90AA1/JAK1/RAC1/ITGA6	1.94602390032611
Human Diseases	Infectious disease: viral	hsa05165	Human papillomavirus infection	14/240	333/9376	1.64244244244244	FN1/PKM/ATP6V1B1/PPP2R2B/ITGB6/CDKN1A/ISG15/EIF4EBP1/CREB5/WNT7A/WNT6/PRKCI/JAK1/ITGA6	1.93469847562587
Environmental Information Processing	Signal transduction	hsa04390	Hippo signaling pathway	8/240	157/9376	1.99065817409766	ACTG1/SERPINE1/PPP2R2B/YWHAZ/ID2/WNT7A/WNT6/PRKCI	2.02882673717834
Human Diseases	Infectious disease: bacterial	hsa05133	Pertussis	5/240	78/9376	2.5042735042735	FOS/JUN/CALM1/SERPING1/CALM2	2.16218350620843
Human Diseases	Cardiovascular disease	hsa05417	Lipid and atherosclerosis	10/240	216/9376	1.80864197530864	FOS/RAP1B/JUN/CYP2J2/CALM1/RAP1A/TNFRSF10B/HSP90AA1/CALM2/RAC1	1.94871637018394
Human Diseases	Cardiovascular disease	hsa05414	Dilated cardiomyopathy	6/240	105/9376	2.23238095238095	TPM1/TPM4/ACTG1/ITGB6/TPM3/ITGA6	2.05820936464009
Environmental Information Processing	Signaling molecules and interaction	hsa04514	Cell adhesion molecule (CAM) interaction	8/240	160/9376	1.95333333333333	CD99/CLDN4/CLDN23/CLDN3/CLDN7/SDC1/CLDN19/ITGA6	1.9712728945459
Human Diseases	Cancer: specific types	hsa05215	Prostate cancer	6/240	106/9376	2.21132075471698	FOLR1/PDGFA/CDKN1A/CREB5/HSP90AA1/PLAU	2.03275687061813
Organismal Systems	Endocrine system	hsa04922	Glucagon signaling pathway	6/240	107/9376	2.19065420560748	LDHA/PKM/CALM1/SIK1/CREB5/CALM2	2.00758670835269
Human Diseases	Infectious disease: viral	hsa05161	Hepatitis B	8/240	163/9376	1.91738241308793	FOS/JUN/YWHAZ/CDKN1A/EGR2/CREB5/JAK1/EGR3	1.91494758136488
Cellular Processes	Cell motility	hsa04814	Motor proteins	9/240	194/9376	1.81237113402062	TPM1/MYL6/TPM4/MYH9/ACTG1/TUBB6/TPM3/DYNLRB1/DYNLL1	1.85310452943059
Human Diseases	Infectious disease: viral	hsa05167	Kaposi sarcoma-associated herpesvirus infection	9/240	196/9376	1.79387755102041	FOS/JUN/CALM1/UBC/ZFP36/CDKN1A/JAK1/CALM2/RAC1	1.82042767812509
Environmental Information Processing	Signal transduction	hsa04024	cAMP signaling pathway	10/240	226/9376	1.72861356932153	FOS/RAP1B/JUN/CALM1/PDE4C/RAP1A/CREB5/CALM2/RAC1/RRAS	1.79702509184768
Human Diseases	Cancer: specific types	hsa05216	Thyroid cancer	3/240	37/9376	3.16756756756757	GADD45A/CDKN1A/TPM3	2.14109793271523
NA	NA	hsa03273	Virion - Lassa virus and SFTS virus	2/240	17/9376	4.59607843137255	TFRC/MYH9	2.40520504372568
Human Diseases	Cardiovascular disease	hsa05412	Arrhythmogenic right ventricular cardiomyopathy	5/240	86/9376	2.27131782945736	ACTG1/ITGB6/PKP2/DSP/ITGA6	1.91959106586798
Human Diseases	Cancer: specific types	hsa05210	Colorectal cancer	5/240	87/9376	2.24521072796935	GADD45A/FOS/JUN/CDKN1A/RAC1	1.89117279633013
Cellular Processes	Cellular community - eukaryotes	hsa04550	Signaling pathways regulating pluripotency of stem cells	7/240	144/9376	1.89907407407407	KLF4/ID3/SKIL/ID2/WNT7A/WNT6/JAK1	1.76214659959203
Human Diseases	Cancer: specific types	hsa05217	Basal cell carcinoma	4/240	63/9376	2.48042328042328	GADD45A/CDKN1A/WNT7A/WNT6	1.91084118337241
Environmental Information Processing	Signaling molecules and interaction	hsa04512	ECM-receptor interaction	5/240	89/9376	2.19475655430712	FN1/ITGB6/SDC1/SV2A/ITGA6	1.83548109545746
Human Diseases	Infectious disease: viral	hsa05169	Epstein-Barr virus infection	9/240	205/9376	1.71512195121951	GADD45A/JUN/B2M/TNFAIP3/CDKN1A/ISG15/JAK1/TAP1/RAC1	1.67788389933941
Environmental Information Processing	Signal transduction	hsa04668	TNF signaling pathway	6/240	119/9376	1.96974789915966	FOS/JUN/JUNB/TNFAIP3/CREB5/SOCS3	1.72548190748731
Metabolism	Glycan biosynthesis and metabolism	hsa00541	Biosynthesis of various nucleotide sugars	2/240	20/9376	3.90666666666667	CYB5R1/UGP2	2.109008524223
Organismal Systems	Nervous system	hsa04720	Long-term potentiation	4/240	67/9376	2.33233830845771	RAP1B/CALM1/RAP1A/CALM2	1.77383661430149
Organismal Systems	Circulatory system	hsa04261	Adrenergic signaling in cardiomyocytes	7/240	154/9376	1.77575757575758	TPM1/TPM4/PPP2R2B/CALM1/TPM3/CREB5/CALM2	1.57321123962504
Organismal Systems	Endocrine system	hsa04921	Oxytocin signaling pathway	7/240	154/9376	1.77575757575758	FOS/MYL6/ACTG1/JUN/CALM1/CDKN1A/CALM2	1.57321123962504
Human Diseases	Endocrine and metabolic disease	hsa04934	Cushing syndrome	7/240	155/9376	1.76430107526882	NR4A1/RAP1B/RAP1A/CDKN1A/CREB5/WNT7A/WNT6	1.5550863963876
Organismal Systems	Endocrine system	hsa04925	Aldosterone synthesis and secretion	5/240	98/9376	1.99319727891156	NR4A1/CALM1/CREB5/CALM2/NR4A2	1.60189700128789
Organismal Systems	Immune system	hsa04621	NOD-like receptor signaling pathway	8/240	187/9376	1.67130124777184	JUN/GBP2/GBP1/TNFAIP3/GBP3/HSP90AA1/JAK1/GABARAP	1.50285591692502
Metabolism	Amino acid metabolism	hsa00340	Histidine metabolism	2/240	22/9376	3.55151515151515	AOC1/CNDP2	1.94188730627425
Human Diseases	Endocrine and metabolic disease	hsa04932	Non-alcoholic fatty liver disease	7/240	157/9376	1.74182590233546	NDUFA13/NDUFA7/FOS/JUN/ADIPOR1/SOCS3/RAC1	1.51922859402081
Genetic Information Processing	Folding, sorting and degradation	hsa03050	Proteasome	3/240	46/9376	2.54782608695652	PSMA2/PSMD9/PSMB8	1.70558539911287
Organismal Systems	Digestive system	hsa04972	Pancreatic secretion	5/240	102/9376	1.91503267973856	RAP1B/RAP1A/BST1/RAC1/RAB11A	1.50597013202108
Human Diseases	Infectious disease: parasitic	hsa05146	Amoebiasis	5/240	103/9376	1.89644012944984	FN1/SERPINB9/ACTN4/ACTN1/VCL	1.48266482944592
Cellular Processes	Cell growth and death	hsa04115	p53 signaling pathway	4/240	75/9376	2.08355555555556	GADD45A/SERPINE1/CDKN1A/TNFRSF10B	1.52696895090173
Environmental Information Processing	Signal transduction	hsa04068	FoxO signaling pathway	6/240	133/9376	1.76240601503759	GADD45A/PLK3/KLF2/CDKN1A/GABARAP/BNIP3	1.43522130173207
Human Diseases	Infectious disease: viral	hsa05163	Human cytomegalovirus infection	9/240	227/9376	1.5488986784141	B2M/CALM1/CDKN1A/EIF4EBP1/CREB5/JAK1/CALM2/TAP1/RAC1	1.35684898320914
Human Diseases	Substance dependence	hsa05030	Cocaine addiction	3/240	49/9376	2.39183673469388	FOSB/JUN/CREB5	1.58317367519175
Organismal Systems	Endocrine system	hsa03320	PPAR signaling pathway	4/240	76/9376	2.05614035087719	PLIN2/SLC27A6/UBC/SCD	1.49830480075291
Human Diseases	Cancer: specific types	hsa05212	Pancreatic cancer	4/240	77/9376	2.02943722943723	GADD45A/CDKN1A/JAK1/RAC1	1.4700778117677
Genetic Information Processing	Folding, sorting and degradation	hsa03018	RNA degradation	4/240	78/9376	2.0034188034188	BTG2/ENO1/BTG1/TOB1	1.44227467970949
Human Diseases	Infectious disease: bacterial	hsa05110	Vibrio cholerae infection	3/240	51/9376	2.29803921568627	ATP6V1B1/ACTG1/KDELR2	1.50647418766782
Organismal Systems	Endocrine system	hsa04910	Insulin signaling pathway	6/240	138/9376	1.69855072463768	CALM1/FLOT1/EIF4EBP1/SOCS3/PRKCI/CALM2	1.33986710635802
Human Diseases	Infectious disease: bacterial	hsa05135	Yersinia infection	6/240	138/9376	1.69855072463768	FN1/FOS/ACTG1/ARPC2/JUN/RAC1	1.33986710635802
Human Diseases	Cancer: specific types	hsa05225	Hepatocellular carcinoma	7/240	170/9376	1.60862745098039	GADD45A/ACTG1/HMOX1/GSTM3/CDKN1A/WNT7A/WNT6	1.29793733639314
Environmental Information Processing	Signal transduction	hsa04371	Apelin signaling pathway	6/240	140/9376	1.67428571428571	SERPINE1/KLF2/CALM1/CALM2/EGR1/RRAS	1.30280443386857
Human Diseases	Neurodegenerative disease	hsa05012	Parkinson disease	10/240	268/9376	1.45771144278607	NDUFA13/NDUFA7/DUSP1/PSMA2/TUBB6/PSMD9/CALM1/UBE2L6/UBC/CALM2	1.23214230629365
Environmental Information Processing	Signal transduction	hsa04350	TGF-beta signaling pathway	5/240	110/9376	1.77575757575758	TFRC/ID3/SKIL/ID2/SKP1	1.32644557014409
Environmental Information Processing	Signal transduction	hsa04014	Ras signaling pathway	9/240	238/9376	1.47731092436975	RAP1B/PDGFA/EFNA1/CALM1/RAP1A/CALM2/RAC1/RRAS/ETS2	1.20886412558619
Metabolism	Metabolism of cofactors and vitamins	hsa00790	Folate biosynthesis	2/240	28/9376	2.79047619047619	CBR1/ALPP	1.53780556293561
Human Diseases	Neurodegenerative disease	hsa05020	Prion disease	10/240	275/9376	1.42060606060606	NDUFA13/NDUFA7/PRNP/PSMA2/TUBB6/PSMD9/CAV2/CREB5/EGR1/RAC1	1.14738859732576
Organismal Systems	Sensory system	hsa04744	Phototransduction	2/240	29/9376	2.69425287356322	CALM1/CALM2	1.48099748875831
Human Diseases	Cancer: specific types	hsa05224	Breast cancer	6/240	148/9376	1.58378378378378	GADD45A/FOS/JUN/CDKN1A/WNT7A/WNT6	1.16022523041711
Human Diseases	Infectious disease: viral	hsa05170	Human immunodeficiency virus 1 infection	8/240	214/9376	1.46043613707165	FOS/JUN/B2M/CALM1/SKP1/CALM2/TAP1/RAC1	1.10431852671284
Organismal Systems	Immune system	hsa04610	Complement and coagulation cascades	4/240	88/9376	1.77575757575758	SERPINE1/SERPING1/CLU/PLAU	1.18500305982159
Environmental Information Processing	Signal transduction	hsa04152	AMPK signaling pathway	5/240	122/9376	1.60109289617486	PPP2R2B/SCD/EIF4EBP1/CREB5/ADIPOR1	1.08310354376495
Organismal Systems	Endocrine system	hsa04935	Growth hormone synthesis, secretion and action	5/240	122/9376	1.60109289617486	FOS/CSH1/JUNB/CREB5/SOCS3	1.08310354376495
Organismal Systems	Immune system	hsa04662	B cell receptor signaling pathway	4/240	91/9376	1.71721611721612	FOS/JUN/DAPP1/RAC1	1.11427656356235
Cellular Processes	Transport and catabolism	hsa04145	Phagosome	6/240	155/9376	1.51225806451613	TFRC/ATP6V1B1/ACTG1/TUBB6/TAP1/RAC1	1.04226668435432
Organismal Systems	Immune system	hsa04658	Th1 and Th2 cell differentiation	4/240	93/9376	1.68028673835125	FOS/GATA3/JUN/JAK1	1.06856886875015
Organismal Systems	Endocrine system	hsa04912	GnRH signaling pathway	4/240	93/9376	1.68028673835125	JUN/CALM1/CALM2/EGR1	1.06856886875015
Human Diseases	Cancer: specific types	hsa05222	Small cell lung cancer	4/240	93/9376	1.68028673835125	FN1/GADD45A/CDKN1A/ITGA6	1.06856886875015
Organismal Systems	Environmental adaptation	hsa04710	Circadian rhythm	2/240	34/9376	2.29803921568627	BHLHE40/SKP1	1.22891134627678
Metabolism	Carbohydrate metabolism	hsa00051	Fructose and mannose metabolism	2/240	35/9376	2.23238095238095	ALDOA/TPI1	1.18384686115977
Human Diseases	Cancer: overview	hsa05208	Chemical carcinogenesis - reactive oxygen species	8/240	227/9376	1.37679882525698	CBR1/NDUFA13/NDUFA7/FOS/JUN/HMOX1/GSTM3/RAC1	0.931427097622964
Organismal Systems	Sensory system	hsa04750	Inflammatory mediator regulation of TRP channels	4/240	99/9376	1.57845117845118	CYP2J2/CALM1/IL1RAP/CALM2	0.937764402216377
Human Diseases	Neurodegenerative disease	hsa05022	Pathways of neurodegeneration - multiple diseases	15/240	480/9376	1.22083333333333	GPX3/NDUFA13/NDUFA7/PRNP/PSMA2/CAPN2/TUBB6/PSMD9/CALM1/UBE2L6/UBC/WNT7A/WNT6/CALM2/RAC1	0.805009625138169
Organismal Systems	Nervous system	hsa04728	Dopaminergic synapse	5/240	133/9376	1.468671679198	FOS/PPP2R2B/CALM1/CREB5/CALM2	0.882269505009525
Human Diseases	Cancer: overview	hsa05202	Transcriptional misregulation in cancer	7/240	201/9376	1.36053067993366	GADD45A/NR4A3/PDGFA/NFKBIZ/CDKN1A/ID2/PLAU	0.83743369938545
Organismal Systems	Endocrine system	hsa04916	Melanogenesis	4/240	101/9376	1.54719471947195	CALM1/WNT7A/WNT6/CALM2	0.896104873102731
Organismal Systems	Circulatory system	hsa04270	Vascular smooth muscle contraction	5/240	134/9376	1.45771144278607	MYL6/CALD1/MYH9/CALM1/CALM2	0.864916934961755
Cellular Processes	Cell growth and death	hsa04217	Necroptosis	6/240	168/9376	1.3952380952381	FTH1/CAPN2/TNFAIP3/TNFRSF10B/HSP90AA1/JAK1	0.837807023467285
Environmental Information Processing	Signal transduction	hsa04630	JAK-STAT signaling pathway	6/240	168/9376	1.3952380952381	CSH1/PDGFA/CDKN1A/SOCS3/JAK1/PIM1	0.837807023467285
Human Diseases	Infectious disease: parasitic	hsa05142	Chagas disease	4/240	103/9376	1.51715210355987	FOS/SERPINE1/PPP2R2B/JUN	0.855342381752554
Human Diseases	Infectious disease: bacterial	hsa05120	Epithelial cell signaling in Helicobacter pylori infection	3/240	71/9376	1.65070422535211	ATP6V1B1/JUN/RAC1	0.892006103596349
Human Diseases	Cancer: specific types	hsa05218	Melanoma	3/240	73/9376	1.60547945205479	GADD45A/PDGFA/CDKN1A	0.841710107642233
Genetic Information Processing	Folding, sorting and degradation	hsa04120	Ubiquitin mediated proteolysis	5/240	142/9376	1.37558685446009	MID1/UBE2L6/UBC/SKP1/SOCS3	0.730925030003921
Environmental Information Processing	Signal transduction	hsa04310	Wnt signaling pathway	6/240	178/9376	1.31685393258427	JUN/FOSL1/WNT7A/WNT6/SKP1/RAC1	0.691728411348949
Organismal Systems	Immune system	hsa04620	Toll-like receptor signaling pathway	4/240	109/9376	1.43363914373089	FOS/JUN/JAK1/RAC1	0.738049277201077
Human Diseases	Endocrine and metabolic disease	hsa04931	Insulin resistance	4/240	109/9376	1.43363914373089	SLC27A6/TRIB3/CREB5/SOCS3	0.738049277201077
Organismal Systems	Digestive system	hsa04971	Gastric acid secretion	3/240	76/9376	1.54210526315789	ACTG1/CALM1/CALM2	0.769063427628988
Cellular Processes	Transport and catabolism	hsa04144	Endocytosis	8/240	250/9376	1.25013333333333	TFRC/FOLR1/ARPC2/CAV2/PRKCI/RAB11FIP1/RAB11A/ARF5	0.649702527641505
Human Diseases	Cancer: overview	hsa05207	Chemical carcinogenesis - receptor activation	7/240	217/9376	1.26021505376344	KLF4/FOS/JUN/GSTM3/EIF4EBP1/CREB5/HSP90AA1	0.628566843380602
Human Diseases	Infectious disease: parasitic	hsa05140	Leishmaniasis	3/240	78/9376	1.5025641025641	FOS/JUN/JAK1	0.722365853210544
Metabolism	Metabolism of cofactors and vitamins	hsa00730	Thiamine metabolism	1/240	15/9376	2.60444444444444	ALPP	1.0079115090313
Metabolism	Metabolism of cofactors and vitamins	hsa00860	Porphyrin metabolism	2/240	46/9376	1.69855072463768	FTH1/HMOX1	0.769749215704496
Organismal Systems	Development and regeneration	hsa04360	Axon guidance	6/240	184/9376	1.27391304347826	EFNB1/SEMA4A/EFNA1/SRGAP1/RAC1/RRAS	0.608176774130769
Human Diseases	Drug resistance: antineoplastic	hsa01521	EGFR tyrosine kinase inhibitor resistance	3/240	80/9376	1.465	PDGFA/EIF4EBP1/JAK1	0.676960147272054
Metabolism	Carbohydrate metabolism	hsa00620	Pyruvate metabolism	2/240	47/9376	1.66241134751773	LDHA/PKM	0.737857268187572
Human Diseases	Endocrine and metabolic disease	hsa04930	Type II diabetes mellitus	2/240	47/9376	1.66241134751773	PKM/SOCS3	0.737857268187572
Metabolism	Amino acid metabolism	hsa00360	Phenylalanine metabolism	1/240	16/9376	2.44166666666667	MIF	0.935405970614173
Organismal Systems	Immune system	hsa04612	Antigen processing and presentation	3/240	82/9376	1.42926829268293	B2M/HSP90AA1/TAP1	0.632772529369136
Metabolism	Metabolism of other amino acids	hsa00430	Taurine and hypotaurine metabolism	1/240	17/9376	2.29803921568627	CDO1	0.868181973253216
Metabolism	Global and overview maps	hsa01240	Biosynthesis of cofactors	5/240	154/9376	1.26839826839827	RDH13/RFK/UGP2/NME3/ALPP	0.544302995852414
Metabolism	Global and overview maps	hsa01232	Nucleotide metabolism	3/240	85/9376	1.37882352941176	GUK1/ADK/NME3	0.568628198080478
Environmental Information Processing	Signal transduction	hsa04012	ErbB signaling pathway	3/240	86/9376	1.36279069767442	JUN/CDKN1A/EIF4EBP1	0.547785743186716
Organismal Systems	Circulatory system	hsa04260	Cardiac muscle contraction	3/240	87/9376	1.34712643678161	TPM1/TPM4/TPM3	0.527200785684646
Metabolism	Glycan biosynthesis and metabolism	hsa00531	Glycosaminoglycan degradation	1/240	19/9376	2.05614035087719	IDS	0.746867110375444
Organismal Systems	Immune system	hsa04611	Platelet activation	4/240	126/9376	1.24021164021164	ACTG1/RAP1B/RAP1A/PRKCI	0.439968585747336
Metabolism	Amino acid metabolism	hsa00270	Cysteine and methionine metabolism	2/240	54/9376	1.44691358024691	LDHA/CDO1	0.533800647034959
Organismal Systems	Aging	hsa04211	Longevity regulating pathway	3/240	90/9376	1.30222222222222	EIF4EBP1/CREB5/ADIPOR1	0.466924350401205
Human Diseases	Cancer: overview	hsa05235	PD-L1 expression and PD-1 checkpoint pathway in cancer	3/240	90/9376	1.30222222222222	FOS/JUN/JAK1	0.466924350401205
Human Diseases	Neurodegenerative disease	hsa05010	Alzheimer disease	11/240	388/9376	1.10756013745704	NDUFA13/NDUFA7/RTN4/PSMA2/CAPN2/TUBB6/PSMD9/CALM1/WNT7A/WNT6/CALM2	0.350710600597986
Metabolism	Nucleotide metabolism	hsa00230	Purine metabolism	4/240	128/9376	1.22083333333333	PDE4C/GUK1/ADK/NME3	0.407717089924456
Human Diseases	Infectious disease: bacterial	hsa05134	Legionellosis	2/240	56/9376	1.3952380952381	EEF1G/BNIP3	0.480792925325465
Organismal Systems	Digestive system	hsa04970	Salivary secretion	3/240	93/9376	1.26021505376344	CALM1/BST1/CALM2	0.408736037256379
Human Diseases	Immune disease	hsa05323	Rheumatoid arthritis	3/240	95/9376	1.23368421052632	FOS/ATP6V1B1/JUN	0.371028268048202
Metabolism	Metabolism of other amino acids	hsa00480	Glutathione metabolism	2/240	59/9376	1.32429378531073	GPX3/GSTM3	0.404985801757806
Human Diseases	Cancer: specific types	hsa05213	Endometrial cancer	2/240	59/9376	1.32429378531073	GADD45A/CDKN1A	0.404985801757806
Genetic Information Processing	Replication and repair	hsa03430	Mismatch repair	1/240	23/9376	1.69855072463768	POLD4	0.543625239419752
Organismal Systems	Endocrine system	hsa04614	Renin-angiotensin system	1/240	23/9376	1.69855072463768	PRCP	0.543625239419752
Organismal Systems	Environmental adaptation	hsa04713	Circadian entrainment	3/240	97/9376	1.20824742268041	FOS/CALM1/CALM2	0.334139738627036
Human Diseases	Infectious disease: viral	hsa05164	Influenza A	5/240	173/9376	1.12909441233141	ACTG1/TNFRSF10B/SOCS3/JAK1/RAB11A	0.277765945157307
Environmental Information Processing	Signal transduction	hsa04070	Phosphatidylinositol signaling system	3/240	98/9376	1.19591836734694	CALM1/CALM2/SYNJ2	0.31599064134994
Human Diseases	Infectious disease: viral	hsa05162	Measles	4/240	136/9376	1.14901960784314	FOS/JUN/TNFAIP3/JAK1	0.283720096155215
Organismal Systems	Digestive system	hsa04978	Mineral absorption	2/240	61/9376	1.28087431693989	FTH1/HMOX1	0.356696403750254
Human Diseases	Drug resistance: antineoplastic	hsa01522	Endocrine resistance	3/240	99/9376	1.18383838383838	FOS/JUN/CDKN1A	0.298032225617079
Human Diseases	Neurodegenerative disease	hsa05014	Amyotrophic lateral sclerosis	10/240	368/9376	1.06159420289855	GPX3/NDUFA13/NDUFA7/HNRNPA1/PSMA2/ACTG1/TUBB6/PSMD9/PFN1/RAC1	0.195372202956634
Cellular Processes	Cell growth and death	hsa04114	Oocyte meiosis	4/240	138/9376	1.13236714975845	YWHAZ/CALM1/SKP1/CALM2	0.253889064413621
Metabolism	Lipid metabolism	hsa00590	Arachidonic acid metabolism	2/240	63/9376	1.24021164021164	CBR1/CYP2J2	0.310050713813823
Human Diseases	Infectious disease: viral	hsa05168	Herpes simplex virus 1 infection	5/240	180/9376	1.08518518518519	B2M/EIF4EBP1/SOCS3/JAK1/TAP1	0.187031198447937
Organismal Systems	Digestive system	hsa04974	Protein digestion and absorption	3/240	103/9376	1.1378640776699	COL17A1/PRCP/DPP4	0.228019934059192
Organismal Systems	Endocrine system	hsa04927	Cortisol synthesis and secretion	2/240	65/9376	1.20205128205128	NR4A1/CREB5	0.264931341799513
Metabolism	Lipid metabolism	hsa01040	Biosynthesis of unsaturated fatty acids	1/240	27/9376	1.44691358024691	SCD	0.376908617791606
Environmental Information Processing	Signal transduction	hsa04064	NF-kappa B signaling pathway	3/240	105/9376	1.11619047619048	GADD45A/TNFAIP3/PLAU	0.194050651071168
Human Diseases	Immune disease	hsa05321	Inflammatory bowel disease	2/240	66/9376	1.18383838383838	GATA3/JUN	0.242910637781502
Organismal Systems	Excretory system	hsa04966	Collecting duct acid secretion	1/240	28/9376	1.3952380952381	ATP6V1B1	0.339462398201213
Human Diseases	Cancer: specific types	hsa05221	Acute myeloid leukemia	2/240	68/9376	1.14901960784314	EIF4EBP1/PIM1	0.199886240069863
Organismal Systems	Endocrine system	hsa04924	Renin secretion	2/240	69/9376	1.13236714975845	CALM1/CALM2	0.178859955918338
Human Diseases	Cancer: specific types	hsa05226	Gastric cancer	4/240	150/9376	1.04177777777778	GADD45A/CDKN1A/WNT7A/WNT6	0.08359830144037
Organismal Systems	Endocrine system	hsa04920	Adipocytokine signaling pathway	2/240	70/9376	1.11619047619048	ADIPOR1/SOCS3	0.158143461704433
Human Diseases	Cancer: overview	hsa05204	Chemical carcinogenesis - DNA adducts	2/240	70/9376	1.11619047619048	CBR1/GSTM3	0.158143461704433
Human Diseases	Cardiovascular disease	hsa05416	Viral myocarditis	2/240	70/9376	1.11619047619048	ACTG1/RAC1	0.158143461704433
Metabolism	Lipid metabolism	hsa00591	Linoleic acid metabolism	1/240	30/9376	1.30222222222222	CYP2J2	0.26871217686666
Human Diseases	Drug resistance: antineoplastic	hsa01523	Antifolate resistance	1/240	30/9376	1.30222222222222	FOLR1	0.26871217686666
Organismal Systems	Endocrine system	hsa04917	Prolactin signaling pathway	2/240	71/9376	1.10046948356808	FOS/SOCS3	0.137726772128152
Human Diseases	Cancer: overview	hsa05230	Central carbon metabolism in cancer	2/240	71/9376	1.10046948356808	LDHA/PKM	0.137726772128152
Metabolism	Metabolism of other amino acids	hsa00410	beta-Alanine metabolism	1/240	31/9376	1.26021505376344	CNDP2	0.235199733379124
NA	NA	hsa04981	Folate transport and metabolism	1/240	31/9376	1.26021505376344	FOLR1	0.235199733379124
Human Diseases	Cancer: specific types	hsa05223	Non-small cell lung cancer	2/240	73/9376	1.0703196347032	GADD45A/CDKN1A	0.0977551708724766
Metabolism	Carbohydrate metabolism	hsa00052	Galactose metabolism	1/240	32/9376	1.22083333333333	UGP2	0.202808622728962
Metabolism	Carbohydrate metabolism	hsa00640	Propanoate metabolism	1/240	32/9376	1.22083333333333	LDHA	0.202808622728962
Cellular Processes	Transport and catabolism	hsa04136	Autophagy - other	1/240	32/9376	1.22083333333333	GABARAP	0.202808622728962
Human Diseases	Immune disease	hsa05310	Asthma	1/240	32/9376	1.22083333333333	PRG2	0.202808622728962
Human Diseases	Drug resistance: antineoplastic	hsa01524	Platinum drug resistance	2/240	75/9376	1.04177777777778	GSTM3/CDKN1A	0.0588741104941601
Organismal Systems	Endocrine system	hsa04918	Thyroid hormone synthesis	2/240	75/9376	1.04177777777778	GPX3/CREB5	0.0588741104941601
Cellular Processes	Cell growth and death	hsa04110	Cell cycle	4/240	158/9376	0.989029535864979	GADD45A/YWHAZ/CDKN1A/SKP1	-0.0225397143135873
Environmental Information Processing	Signal transduction	hsa04150	mTOR signaling pathway	4/240	158/9376	0.989029535864979	ATP6V1B1/EIF4EBP1/WNT7A/WNT6	-0.0225397143135873
Genetic Information Processing	Chromosome	hsa03082	ATP-dependent chromatin remodeling	3/240	117/9376	1.0017094017094	ACTG1/SMARCA1/MORF4L2	0.00301556182187756
Human Diseases	Cancer: overview	hsa05206	MicroRNAs in cancer	8/240	323/9376	0.967595459236326	TIMP3/TPM1/PDGFA/EFNA1/HMOX1/CDKN1A/PLAU/PIM1	-0.0960559088710602
Human Diseases	Cancer: specific types	hsa05220	Chronic myeloid leukemia	2/240	77/9376	1.01471861471861	GADD45A/CDKN1A	0.0210187744323389
Metabolism	Carbohydrate metabolism	hsa00562	Inositol phosphate metabolism	2/240	78/9376	1.0017094017094	TPI1/SYNJ2	0.00245702671160053
Metabolism	Xenobiotics biodegradation and metabolism	hsa00980	Metabolism of xenobiotics by cytochrome P450	2/240	79/9376	0.989029535864979	CBR1/GSTM3	-0.0158701249368146
Metabolism	Carbohydrate metabolism	hsa00040	Pentose and glucuronate interconversions	1/240	36/9376	1.08518518518519	UGP2	0.0829956055049914
Metabolism	Carbohydrate metabolism	hsa00500	Starch and sucrose metabolism	1/240	36/9376	1.08518518518519	UGP2	0.0829956055049914
Genetic Information Processing	Replication and repair	hsa03030	DNA replication	1/240	36/9376	1.08518518518519	POLD4	0.0829956055049914
Organismal Systems	Immune system	hsa04660	T cell receptor signaling pathway	3/240	122/9376	0.960655737704918	FOS/PPP2R2B/JUN	-0.0708940501373421
Metabolism	Amino acid metabolism	hsa00350	Tyrosine metabolism	1/240	37/9376	1.05585585585586	MIF	0.0551737621896692
Metabolism	Global and overview maps	hsa01250	Biosynthesis of nucleotide sugars	1/240	37/9376	1.05585585585586	UGP2	0.0551737621896692
Cellular Processes	Transport and catabolism	hsa04142	Lysosome biogenesis	6/240	250/9376	0.9376	LAPTM4A/ATP6V1B1/CTSV/IDS/CTSH/LAPTM4B	-0.162079308601399
Environmental Information Processing	Signal transduction	hsa04071	Sphingolipid signaling pathway	3/240	125/9376	0.9376	SPTSSA/PPP2R2B/RAC1	-0.113830454347222
Metabolism	Xenobiotics biodegradation and metabolism	hsa00983	Drug metabolism - other enzymes	2/240	82/9376	0.952845528455285	GSTM3/NME3	-0.0695091036049429
Metabolism	Carbohydrate metabolism	hsa00520	Amino sugar and nucleotide sugar metabolism	1/240	38/9376	1.0280701754386	UGP2	0.0281010924731912
Metabolism	Metabolism of cofactors and vitamins	hsa00760	Nicotinate and nicotinamide metabolism	1/240	38/9376	1.0280701754386	BST1	0.0281010924731912
Human Diseases	Immune disease	hsa05340	Primary immunodeficiency	1/240	38/9376	1.0280701754386	TAP1	0.0281010924731912
Cellular Processes	Transport and catabolism	hsa04140	Autophagy - animal	4/240	169/9376	0.92465483234714	UBC/GABARAP/RRAS/BNIP3	-0.160196453744596
Organismal Systems	Endocrine system	hsa04926	Relaxin signaling pathway	3/240	130/9376	0.901538461538462	FOS/JUN/CREB5	-0.183220710338203
Genetic Information Processing	Folding, sorting and degradation	hsa04141	Protein processing in endoplasmic reticulum	4/240	174/9376	0.898084291187739	KRTCAP2/CAPN2/SKP1/HSP90AA1	-0.219931710827929
Genetic Information Processing	Replication and repair	hsa03440	Homologous recombination	1/240	41/9376	0.952845528455285	POLD4	-0.0490423037591504
Human Diseases	Cancer: specific types	hsa05219	Bladder cancer	1/240	41/9376	0.952845528455285	CDKN1A	-0.0490423037591504
Metabolism	Amino acid metabolism	hsa00380	Tryptophan metabolism	1/240	42/9376	0.93015873015873	AOC1	-0.0735217926230041
Cellular Processes	Cellular community - eukaryotes	hsa04540	Gap junction	2/240	89/9376	0.877902621722846	TUBB6/PDGFA	-0.187575811009132
Organismal Systems	Digestive system	hsa04975	Fat digestion and absorption	1/240	43/9376	0.908527131782946	AGPAT2	-0.0974381670087797
Human Diseases	Neurodegenerative disease	hsa05016	Huntington disease	7/240	308/9376	0.887878787878788	GPX3/NDUFA13/NDUFA7/PSMA2/TUBB6/PSMD9/CREB5	-0.324280325532472
Metabolism	Glycan biosynthesis and metabolism	hsa00513	Various types of N-glycan biosynthesis	1/240	44/9376	0.887878787878788	KRTCAP2	-0.120820317030419
Genetic Information Processing	Replication and repair	hsa03410	Base excision repair	1/240	44/9376	0.887878787878788	POLD4	-0.120820317030419
Human Diseases	Infectious disease: bacterial	hsa05152	Tuberculosis	4/240	181/9376	0.863351749539595	PLK3/CALM1/JAK1/CALM2	-0.300871263569226
Environmental Information Processing	Membrane transport	hsa02010	ABC transporters	1/240	45/9376	0.868148148148148	TAP1	-0.143694984406776
Metabolism	Energy metabolism	hsa00190	Oxidative phosphorylation	3/240	138/9376	0.84927536231884	NDUFA13/NDUFA7/ATP6V1B1	-0.289099956558576
Organismal Systems	Immune system	hsa04666	Fc gamma R-mediated phagocytosis	2/240	98/9376	0.797278911564626	ARPC2/RAC1	-0.326962538619035
Organismal Systems	Environmental adaptation	hsa04714	Thermogenesis	5/240	235/9376	0.831205673758865	NDUFA13/NDUFA7/ACTG1/CREB5/COX16	-0.424725302829456
Human Diseases	Infectious disease: bacterial	hsa05150	Staphylococcus aureus infection	2/240	99/9376	0.789225589225589	KRT19/KRT18	-0.341699950982219
Human Diseases	Substance dependence	hsa05034	Alcoholism	4/240	191/9376	0.818150087260035	FOSB/CALM1/CREB5/CALM2	-0.411531813393777
Human Diseases	Infectious disease: parasitic	hsa05144	Malaria	1/240	50/9376	0.781333333333333	SDC1	-0.251265634787794
Organismal Systems	Immune system	hsa04640	Hematopoietic cell lineage	2/240	100/9376	0.781333333333333	TFRC/ITGA6	-0.356299676698133
Metabolism	Lipid metabolism	hsa00565	Ether lipid metabolism	1/240	51/9376	0.766013071895425	LPCAT1	-0.271559798179798
Environmental Information Processing	Signal transduction	hsa04072	Phospholipase D signaling pathway	3/240	149/9376	0.786577181208054	PDGFA/AGPAT2/RRAS	-0.425615013356394
Organismal Systems	Endocrine system	hsa04913	Ovarian steroidogenesis	1/240	52/9376	0.751282051282051	CYP2J2	-0.291488134129611
Organismal Systems	Excretory system	hsa04961	Endocrine and other factor-regulated calcium reabsorption	1/240	53/9376	0.737106918238994	RAB11A	-0.311065942063707
Metabolism	Lipid metabolism	hsa00564	Glycerophospholipid metabolism	2/240	104/9376	0.751282051282051	LPCAT1/AGPAT2	-0.41338079773382
Metabolism	Glycan biosynthesis and metabolism	hsa00510	N-Glycan biosynthesis	1/240	56/9376	0.697619047619048	KRTCAP2	-0.367835551303217
Cellular Processes	Transport and catabolism	hsa04148	Efferocytosis	3/240	157/9376	0.746496815286624	DUSP5/SLC16A1/RAC1	-0.519163978609288
Metabolism	Global and overview maps	hsa01212	Fatty acid metabolism	1/240	57/9376	0.685380116959064	SCD	-0.386146542736832
Metabolism	Nucleotide metabolism	hsa00240	Pyrimidine metabolism	1/240	59/9376	0.662146892655367	NME3	-0.421919006012488
Human Diseases	Infectious disease: parasitic	hsa05145	Toxoplasmosis	2/240	112/9376	0.697619047619048	JAK1/ITGA6	-0.521767930293569
Environmental Information Processing	Signal transduction	hsa04370	VEGF signaling pathway	1/240	60/9376	0.651111111111111	RAC1	-0.439401198846056
Organismal Systems	Nervous system	hsa04725	Cholinergic synapse	2/240	115/9376	0.679420289855072	FOS/CREB5	-0.560620821657738
Organismal Systems	Nervous system	hsa04726	Serotonergic synapse	2/240	115/9376	0.679420289855072	DUSP1/CYP2J2	-0.560620821657738
Environmental Information Processing	Signal transduction	hsa04022	cGMP-PKG signaling pathway	3/240	166/9376	0.706024096385542	CALM1/CREB5/CALM2	-0.61936858894229
Metabolism	Amino acid metabolism	hsa00310	Lysine degradation	1/240	63/9376	0.62010582010582	SMYD2	-0.490344520965473
Genetic Information Processing	Replication and repair	hsa03420	Nucleotide excision repair	1/240	63/9376	0.62010582010582	POLD4	-0.490344520965473
Metabolism	Lipid metabolism	hsa00561	Glycerolipid metabolism	1/240	65/9376	0.601025641025641	AGPAT2	-0.523138537868074
Metabolism	Metabolism of cofactors and vitamins	hsa00830	Retinol metabolism	1/240	68/9376	0.574509803921569	RDH13	-0.570727817041584
Organismal Systems	Immune system	hsa04664	Fc epsilon RI signaling pathway	1/240	69/9376	0.566183574879227	RAC1	-0.58619065844769
Organismal Systems	Immune system	hsa04622	RIG-I-like receptor signaling pathway	1/240	72/9376	0.542592592592593	ISG15	-0.631462848566411
Metabolism	Xenobiotics biodegradation and metabolism	hsa00982	Drug metabolism - cytochrome P450	1/240	73/9376	0.535159817351598	GSTM3	-0.64619976589728
Organismal Systems	Immune system	hsa04650	Natural killer cell mediated cytotoxicity	2/240	133/9376	0.587468671679198	TNFRSF10B/RAC1	-0.776585885158117
Organismal Systems	Nervous system	hsa04721	Synaptic vesicle cycle	1/240	79/9376	0.494514767932489	ATP6V1B1	-0.731246525934767
Organismal Systems	Immune system	hsa04062	Chemokine signaling pathway	3/240	193/9376	0.607253886010363	RAP1B/RAP1A/RAC1	-0.893534802426093
Environmental Information Processing	Signaling molecules and interaction	hsa04060	Cytokine-cytokine receptor interaction	5/240	298/9376	0.655480984340045	CSH1/EBI3/IL1RAP/GDF15/TNFRSF10B	-0.979578972711109
Genetic Information Processing	Chromosome	hsa03083	Polycomb repressive complex	1/240	83/9376	0.470682730923695	SKP1	-0.785037412472884
Cellular Processes	Transport and catabolism	hsa04146	Peroxisome	1/240	83/9376	0.470682730923695	ECH1	-0.785037412472884
Human Diseases	Immune disease	hsa05322	Systemic lupus erythematosus	2/240	143/9376	0.546386946386946	ACTN4/ACTN1	-0.885921738280764
Human Diseases	Endocrine and metabolic disease	hsa04936	Alcoholic liver disease	2/240	144/9376	0.542592592592593	SCD/ADIPOR1	-0.896498887948984
Human Diseases	Neurodegenerative disease	hsa05017	Spinocerebellar ataxia	2/240	144/9376	0.542592592592593	PSMA2/PSMD9	-0.896498887948984
Organismal Systems	Endocrine system	hsa04911	Insulin secretion	1/240	86/9376	0.454263565891473	CREB5	-0.824019579494547
Organismal Systems	Nervous system	hsa04723	Retrograde endocannabinoid signaling	2/240	149/9376	0.524384787472036	NDUFA13/NDUFA7	-0.948487964775359
Human Diseases	Cardiovascular disease	hsa05415	Diabetic cardiomyopathy	3/240	205/9376	0.571707317073171	NDUFA13/NDUFA7/RAC1	-1.00489908841746
Organismal Systems	Nervous system	hsa04727	GABAergic synapse	1/240	89/9376	0.438951310861423	GABARAP	-0.861928113164661
Human Diseases	Substance dependence	hsa05032	Morphine addiction	1/240	91/9376	0.429304029304029	PDE4C	-0.88664090195615
Environmental Information Processing	Signaling molecules and interaction	hsa04061	Viral protein interaction with cytokine and cytokine receptor	1/240	100/9376	0.390666666666667	TNFRSF10B	-0.992859464945408
Genetic Information Processing	Translation	hsa03015	mRNA surveillance pathway	1/240	103/9376	0.379288025889968	PPP2R2B	-1.02662496132753
Genetic Information Processing	Translation	hsa03013	Nucleocytoplasmic transport	1/240	108/9376	0.361728395061728	SUMO2	-1.08127858809419
Organismal Systems	Endocrine system	hsa04914	Progesterone-mediated oocyte maturation	1/240	110/9376	0.355151515151515	HSP90AA1	-1.10260788018227
Organismal Systems	Endocrine system	hsa04919	Thyroid hormone signaling pathway	1/240	122/9376	0.320218579234973	ACTG1	-1.22489164403963
Environmental Information Processing	Signal transduction	hsa04020	Calcium signaling pathway	3/240	254/9376	0.461417322834646	PDGFA/CALM1/CALM2	-1.41038415013267
Organismal Systems	Immune system	hsa04613	Neutrophil extracellular trap formation	2/240	195/9376	0.400683760683761	ACTG1/RAC1	-1.37069734406916
NA	NA	hsa04081	Hormone signaling	2/240	219/9376	0.356773211567732	CSH1/ADIPOR1	-1.56107147149171
Genetic Information Processing	Transcription	hsa03040	Spliceosome	1/240	243/9376	0.16076817558299	HNRNPA1	-2.14828336680034
Environmental Information Processing	Signaling molecules and interaction	hsa04080	Neuroactive ligand-receptor interaction	2/240	370/9376	0.211171171171171	CSH1/NPFFR2	-2.50917457599267
Organismal Systems	Sensory system	hsa04740	Olfactory transduction	2/240	449/9376	0.174016332590943	CALM1/CALM2	-2.90706723700714