category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Human Diseases	Neurodegenerative disease	hsa05020	Prion disease	11/66	275/9376	5.68242424242424	MT-ATP8/MT-ND4L/MT-ND6/MT-ND5/MT-CYB/HSPA1A/MT-ND3/C1QB/C1QA/MT-ND4/SLC25A5	6.63552538268074
Human Diseases	Cancer: overview	hsa05208	Chemical carcinogenesis - reactive oxygen species	10/66	227/9376	6.2581764784408	MT-ATP8/MT-ND4L/MT-ND6/MT-ND5/MT-CYB/MGST3/GSTA3/MT-ND3/MT-ND4/SLC25A5	6.75218042223081
Metabolism	Energy metabolism	hsa00190	Oxidative phosphorylation	7/66	138/9376	7.20597277119016	MT-ATP8/MT-ND4L/MT-ND6/MT-ND5/MT-CYB/MT-ND3/MT-ND4	6.18362572852445
Human Diseases	Neurodegenerative disease	hsa05016	Huntington disease	10/66	308/9376	4.61235733963007	MT-ATP8/MT-ND4L/MT-ND6/MT-ND5/MT-CYB/MT-ND3/AP2S1/MT-ND4/SLC25A5/TFAM	5.42741552758282
Human Diseases	Cardiovascular disease	hsa05415	Diabetic cardiomyopathy	8/66	205/9376	5.54382852919438	MT-ATP8/MT-ND4L/MT-ND6/MT-ND5/MT-CYB/MT-ND3/MT-ND4/SLC25A5	5.53825927247956
Human Diseases	Neurodegenerative disease	hsa05012	Parkinson disease	9/66	268/9376	4.77069199457259	MT-ATP8/MT-ND4L/MT-ND6/MT-ND5/MT-CYB/MT-ND3/MT-ND4/SLC39A1/SLC25A5	5.27302354381517
Human Diseases	Endocrine and metabolic disease	hsa04940	Type I diabetes mellitus	4/66	44/9376	12.9146005509642	HLA-DRA/HLA-C/HLA-DRB1/HSPD1	6.66962206755724
Human Diseases	Neurodegenerative disease	hsa05010	Alzheimer disease	10/66	388/9376	3.66135582630428	MT-ATP8/MT-ND4L/MT-ND6/MT-ND5/MT-CYB/MT-ND3/MME/MT-ND4/SLC39A1/SLC25A5	4.50785606344221
Organismal Systems	Nervous system	hsa04723	Retrograde endocannabinoid signaling	6/66	149/9376	5.72056131787675	MT-ND4L/MT-ND6/MT-ND5/MT-ND3/MT-ND4/GABRE	4.89034257018723
Organismal Systems	Environmental adaptation	hsa04714	Thermogenesis	7/66	235/9376	4.23159252095422	MT-ATP8/MT-ND4L/MT-ND6/MT-ND5/MT-CYB/MT-ND3/MT-ND4	4.22412184055048
Metabolism	Carbohydrate metabolism	hsa00630	Glyoxylate and dicarboxylate metabolism	3/66	31/9376	13.7478005865103	ACSS1/GCSH/GLUL	5.98562108543983
Metabolism	Carbohydrate metabolism	hsa00640	Propanoate metabolism	3/66	32/9376	13.3181818181818	ECHS1/ACSS1/LDHB	5.87675992976902
Human Diseases	Cardiovascular disease	hsa05416	Viral myocarditis	4/66	70/9376	8.11774891774892	CCND1/HLA-DRA/HLA-C/HLA-DRB1	5.03260593415179
Human Diseases	Immune disease	hsa05330	Allograft rejection	3/66	39/9376	10.9277389277389	HLA-DRA/HLA-C/HLA-DRB1	5.230723186605
Organismal Systems	Immune system	hsa04612	Antigen processing and presentation	4/66	82/9376	6.92978566149298	HSPA1A/HLA-DRA/HLA-C/HLA-DRB1	4.54074750732001
Human Diseases	Infectious disease: viral	hsa05169	Epstein-Barr virus infection	6/66	205/9376	4.15787139689579	PLCG2/CCND1/HLA-DRA/HLA-C/HLA-DRB1/CD44	3.84898119125479
Human Diseases	Immune disease	hsa05332	Graft-versus-host disease	3/66	45/9376	9.47070707070707	HLA-DRA/HLA-C/HLA-DRB1	4.79561810493873
Human Diseases	Neurodegenerative disease	hsa05014	Amyotrophic lateral sclerosis	8/66	368/9376	3.08827404479578	MT-ATP8/MT-ND4L/MT-ND6/MT-ND5/MT-CYB/MT-ND3/MT-ND4/TOMM40	3.44096279367327
Human Diseases	Infectious disease: bacterial	hsa05150	Staphylococcus aureus infection	4/66	99/9376	5.73982246709519	C1QB/C1QA/HLA-DRA/HLA-DRB1	3.9917070374498
Metabolism	Amino acid metabolism	hsa00330	Arginine and proline metabolism	3/66	50/9376	8.52363636363636	SAT1/CKMT1A/ARG2	4.49104967657427
Organismal Systems	Immune system	hsa04640	Hematopoietic cell lineage	4/66	100/9376	5.68242424242424	MME/HLA-DRA/HLA-DRB1/CD44	3.96344791257945
Human Diseases	Neurodegenerative disease	hsa05022	Pathways of neurodegeneration - multiple diseases	9/66	480/9376	2.66363636363636	MT-ATP8/MT-ND4L/MT-ND6/MT-ND5/MT-CYB/MT-ND3/MT-ND4/TOMM40/SLC25A5	3.15039059023876
Human Diseases	Immune disease	hsa05320	Autoimmune thyroid disease	3/66	54/9376	7.89225589225589	HLA-DRA/HLA-C/HLA-DRB1	4.27648043476922
Metabolism	Metabolism of other amino acids	hsa00480	Glutathione metabolism	3/66	59/9376	7.22342064714946	MGST3/GSTA3/GPX4	4.03738234829865
Organismal Systems	Digestive system	hsa04978	Mineral absorption	3/66	61/9376	6.98658718330849	MT2A/SLC34A2/ATP2B1	3.94944040498691
Metabolism	Amino acid metabolism	hsa00220	Arginine biosynthesis	2/66	23/9376	12.3530961791831	ARG2/GLUL	4.58971304132563
Human Diseases	Immune disease	hsa05322	Systemic lupus erythematosus	4/66	143/9376	3.97372324645052	C1QB/C1QA/HLA-DRA/HLA-DRB1	3.01703198455842
Human Diseases	Infectious disease: viral	hsa05166	Human T-cell leukemia virus 1 infection	5/66	224/9376	3.17099567099567	CCND1/HLA-DRA/HLA-C/HLA-DRB1/SLC25A5	2.76890290147317
Human Diseases	Immune disease	hsa05310	Asthma	2/66	32/9376	8.87878787878788	HLA-DRA/HLA-DRB1	3.75881323921265
Organismal Systems	Immune system	hsa04610	Complement and coagulation cascades	3/66	88/9376	4.84297520661157	CD46/C1QB/C1QA	3.04951364374798
Cellular Processes	Transport and catabolism	hsa04148	Efferocytosis	4/66	157/9376	3.61937849835939	BSG/C1QB/C1QA/ARG2	2.78669181758909
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	5/66	238/9376	2.98446651387828	PLCG2/RPS21/C1QB/C1QA/RPL3	2.61089521384663
Human Diseases	Cancer: specific types	hsa05225	Hepatocellular carcinoma	4/66	170/9376	3.34260249554367	PLCG2/MGST3/GSTA3/CCND1	2.5951970716704
Cellular Processes	Cell growth and death	hsa04216	Ferroptosis	2/66	42/9376	6.76479076479076	SAT1/GPX4	3.15251427246315
Metabolism	Carbohydrate metabolism	hsa00620	Pyruvate metabolism	2/66	47/9376	6.04513217279175	ACSS1/LDHB	2.91935356786397
Human Diseases	Infectious disease: parasitic	hsa05145	Toxoplasmosis	3/66	112/9376	3.80519480519481	HSPA1A/HLA-DRA/HLA-DRB1	2.51452252056311
Metabolism	Global and overview maps	hsa01200	Carbon metabolism	3/66	116/9376	3.67398119122257	ECHS1/ACSS1/GCSH	2.43985835828479
Organismal Systems	Immune system	hsa04672	Intestinal immune network for IgA production	2/66	50/9376	5.68242424242424	HLA-DRA/HLA-DRB1	2.7950579830202
Organismal Systems	Excretory system	hsa04961	Endocrine and other factor-regulated calcium reabsorption	2/66	53/9376	5.36077758719268	ATP2B1/AP2S1	2.68044435014049
Human Diseases	Cancer: overview	hsa05205	Proteoglycans in cancer	4/66	204/9376	2.78550207961973	PLCG2/CCND1/TWIST1/CD44	2.1708318584638
Human Diseases	Infectious disease: bacterial	hsa05134	Legionellosis	2/66	56/9376	5.07359307359307	HSPA1A/HSPD1	2.57422477848078
Environmental Information Processing	Signal transduction	hsa04370	VEGF signaling pathway	2/66	60/9376	4.73535353535353	PLCG2/HSPB1	2.44385459711567
Human Diseases	Infectious disease: viral	hsa05162	Measles	3/66	136/9376	3.13368983957219	HSPA1A/CD46/CCND1	2.11031615315537
Human Diseases	Immune disease	hsa05321	Inflammatory bowel disease	2/66	66/9376	4.3048668503214	HLA-DRA/HLA-DRB1	2.2684742803438
Metabolism	Carbohydrate metabolism	hsa00010	Glycolysis / Gluconeogenesis	2/66	67/9376	4.24061510628675	ACSS1/LDHB	2.24127993859741
Human Diseases	Endocrine and metabolic disease	hsa04936	Alcoholic liver disease	3/66	144/9376	2.95959595959596	C1QB/C1QA/CCND1	1.99518260132557
Genetic Information Processing	Information processing in viruses	hsa03265	Virion - Ebolavirus, Lyssavirus and Morbillivirus	1/66	12/9376	11.8383838383838	CD46	3.16305842133348
Human Diseases	Cancer: overview	hsa05204	Chemical carcinogenesis - DNA adducts	2/66	70/9376	4.05887445887446	MGST3/GSTA3	2.16277785736021
Metabolism	Xenobiotics biodegradation and metabolism	hsa00982	Drug metabolism - cytochrome P450	2/66	73/9376	3.89207139892071	MGST3/GSTA3	2.08853470164942
Human Diseases	Cancer: specific types	hsa05223	Non-small cell lung cancer	2/66	73/9376	3.89207139892071	PLCG2/CCND1	2.08853470164942
Cellular Processes	Transport and catabolism	hsa04145	Phagosome	3/66	155/9376	2.74956011730205	HLA-DRA/HLA-C/HLA-DRB1	1.8492195390319
Metabolism	Global and overview maps	hsa01230	Biosynthesis of amino acids	2/66	75/9376	3.78828282828283	ARG2/GLUL	2.04119924547876
Human Diseases	Drug resistance: antineoplastic	hsa01524	Platinum drug resistance	2/66	75/9376	3.78828282828283	MGST3/GSTA3	2.04119924547876
Cellular Processes	Cell growth and death	hsa04218	Cellular senescence	3/66	157/9376	2.71453387376954	CCND1/HLA-C/SLC25A5	1.8240500637863
Human Diseases	Cancer: specific types	hsa05214	Glioma	2/66	76/9376	3.7384370015949	PLCG2/CCND1	2.01813791524135
Environmental Information Processing	Signaling molecules and interaction	hsa04514	Cell adhesion molecule (CAM) interaction	3/66	160/9376	2.66363636363636	HLA-DRA/HLA-C/HLA-DRB1	1.78702212019073
Environmental Information Processing	Signal transduction	hsa04020	Calcium signaling pathway	4/66	254/9376	2.23717489859222	PLCG2/ATP2B1/MCOLN3/SLC25A5	1.68300609869865
Human Diseases	Infectious disease: bacterial	hsa05133	Pertussis	2/66	78/9376	3.64257964257964	C1QB/C1QA	1.97316489816971
Human Diseases	Infectious disease: parasitic	hsa05140	Leishmaniasis	2/66	78/9376	3.64257964257964	HLA-DRA/HLA-DRB1	1.97316489816971
Metabolism	Xenobiotics biodegradation and metabolism	hsa00980	Metabolism of xenobiotics by cytochrome P450	2/66	79/9376	3.59647103950901	MGST3/GSTA3	1.95122961350532
Metabolism	Energy metabolism	hsa00910	Nitrogen metabolism	1/66	17/9376	8.35650623885918	GLUL	2.55601919042046
NA	NA	hsa03273	Virion - Lassa virus and SFTS virus	1/66	17/9376	8.35650623885918	NRP2	2.55601919042046
Metabolism	Xenobiotics biodegradation and metabolism	hsa00983	Drug metabolism - other enzymes	2/66	82/9376	3.46489283074649	MGST3/GSTA3	1.88749756162436
Cellular Processes	Cell growth and death	hsa04217	Necroptosis	3/66	168/9376	2.53679653679654	HMGB1/GLUL/SLC25A5	1.69227572297894
Human Diseases	Infectious disease: viral	hsa05164	Influenza A	3/66	173/9376	2.46347871781398	HLA-DRA/HLA-DRB1/SLC25A5	1.63578988076462
Genetic Information Processing	Folding, sorting and degradation	hsa04141	Protein processing in endoplasmic reticulum	3/66	174/9376	2.44932079414838	RRBP1/TUSC3/HSPA1A	1.62472849920173
Metabolism	Metabolism of cofactors and vitamins	hsa00785	Lipoic acid metabolism	1/66	19/9376	7.47687400318979	GCSH	2.37934106355183
Organismal Systems	Nervous system	hsa04727	GABAergic synapse	2/66	89/9376	3.19237316990126	GABRE/GLUL	1.74966347005052
Environmental Information Processing	Signal transduction	hsa04310	Wnt signaling pathway	3/66	178/9376	2.39427987742594	NOTUM/RNF43/CCND1	1.58123356139136
Human Diseases	Infectious disease: viral	hsa05168	Herpes simplex virus 1 infection	3/66	180/9376	2.36767676767677	HLA-DRA/HLA-C/HLA-DRB1	1.55992244322493
Human Diseases	Infectious disease: bacterial	hsa05152	Tuberculosis	3/66	181/9376	2.35459568056253	HLA-DRA/HLA-DRB1/HSPD1	1.54937260417057
Organismal Systems	Immune system	hsa04658	Th1 and Th2 cell differentiation	2/66	93/9376	3.05506679700228	HLA-DRA/HLA-DRB1	1.67689553013948
Human Diseases	Immune disease	hsa05323	Rheumatoid arthritis	2/66	95/9376	2.99074960127592	HLA-DRA/HLA-DRB1	1.64196471156004
Organismal Systems	Endocrine system	hsa04614	Renin-angiotensin system	1/66	23/9376	6.17654808959157	MME	2.09272165943698
Organismal Systems	Immune system	hsa04613	Neutrophil extracellular trap formation	3/66	195/9376	2.18554778554779	PLCG2/HMGB1/SLC25A5	1.40855607523746
Human Diseases	Endocrine and metabolic disease	hsa04933	AGE-RAGE signaling pathway in diabetic complications	2/66	101/9376	2.81308130813081	PLCG2/CCND1	1.54242399863423
Human Diseases	Infectious disease: viral	hsa05167	Kaposi sarcoma-associated herpesvirus infection	3/66	196/9376	2.17439703153989	PLCG2/CCND1/HLA-C	1.39895712782177
Organismal Systems	Digestive system	hsa04974	Protein digestion and absorption	2/66	103/9376	2.75845837010886	COL14A1/MME	1.51085692391249
Human Diseases	Infectious disease: parasitic	hsa05142	Chagas disease	2/66	103/9376	2.75845837010886	C1QB/C1QA	1.51085692391249
Human Diseases	Infectious disease: parasitic	hsa05146	Amoebiasis	2/66	103/9376	2.75845837010886	ARG2/HSPB1	1.51085692391249
Metabolism	Carbohydrate metabolism	hsa00650	Butanoate metabolism	1/66	27/9376	5.26150392817059	ECHS1	1.8670027634512
Organismal Systems	Immune system	hsa04659	Th17 cell differentiation	2/66	109/9376	2.60661662496525	HLA-DRA/HLA-DRB1	1.42049166442852
Metabolism	Lipid metabolism	hsa00062	Fatty acid elongation	1/66	28/9376	5.07359307359307	ECHS1	1.8175236589027
Environmental Information Processing	Signal transduction	hsa04066	HIF-1 signaling pathway	2/66	110/9376	2.58292011019284	PLCG2/LDHB	1.40602148398015
Human Diseases	Cancer: overview	hsa05207	Chemical carcinogenesis - receptor activation	3/66	217/9376	1.96397151235861	MGST3/GSTA3/CCND1	1.20963070562499
Metabolism	Metabolism of other amino acids	hsa00410	beta-Alanine metabolism	1/66	31/9376	4.58260019550342	ECHS1	1.68217937873913
Organismal Systems	Endocrine system	hsa04919	Thyroid hormone signaling pathway	2/66	122/9376	2.32886239443617	PLCG2/CCND1	1.24387845258788
Metabolism	Glycan biosynthesis and metabolism	hsa00512	Mucin type O-glycan biosynthesis	1/66	36/9376	3.94612794612795	GALNT11	1.49111857900369
Metabolism	Amino acid metabolism	hsa00250	Alanine, aspartate and glutamate metabolism	1/66	37/9376	3.83947583947584	GLUL	1.45704047955621
Human Diseases	Cancer: specific types	hsa05216	Thyroid cancer	1/66	37/9376	3.83947583947584	CCND1	1.45704047955621
Metabolism	Metabolism of cofactors and vitamins	hsa00760	Nicotinate and nicotinamide metabolism	1/66	38/9376	3.7384370015949	PNP	1.42413245335304
Organismal Systems	Immune system	hsa04650	Natural killer cell mediated cytotoxicity	2/66	133/9376	2.13624971519708	PLCG2/HLA-C	1.11115820319293
Metabolism	Metabolism of cofactors and vitamins	hsa00670	One carbon pool by folate	1/66	39/9376	3.64257964257964	GCSH	1.3923213240701
Metabolism	Amino acid metabolism	hsa00260	Glycine, serine and threonine metabolism	1/66	41/9376	3.46489283074649	GCSH	1.33172813287805
Human Diseases	Substance dependence	hsa05033	Nicotine addiction	1/66	41/9376	3.46489283074649	GABRE	1.33172813287805
Human Diseases	Cancer: specific types	hsa05219	Bladder cancer	1/66	41/9376	3.46489283074649	CCND1	1.33172813287805
Metabolism	Amino acid metabolism	hsa00380	Tryptophan metabolism	1/66	42/9376	3.38239538239538	ECHS1	1.30282880196162
Cellular Processes	Transport and catabolism	hsa04144	Endocytosis	3/66	250/9376	1.70472727272727	HSPA1A/AP2S1/HLA-C	0.950897304878642
Environmental Information Processing	Signal transduction	hsa04371	Apelin signaling pathway	2/66	140/9376	2.02943722943723	CCND1/TFAM	1.03324828138596
Metabolism	Lipid metabolism	hsa00071	Fatty acid degradation	1/66	43/9376	3.30373502466526	ECHS1	1.27479069700756
Human Diseases	Cardiovascular disease	hsa05418	Fluid shear stress and atherosclerosis	2/66	142/9376	2.00085360648741	MGST3/GSTA3	1.01181837249293
Metabolism	Glycan biosynthesis and metabolism	hsa00513	Various types of N-glycan biosynthesis	1/66	44/9376	3.22865013774105	TUSC3	1.24756630119163
Genetic Information Processing	Replication and repair	hsa03410	Base excision repair	1/66	44/9376	3.22865013774105	HMGB1	1.24756630119163
Metabolism	Amino acid metabolism	hsa00280	Valine, leucine and isoleucine degradation	1/66	48/9376	2.95959595959596	ECHS1	1.14597633888765
Metabolism	Glycan biosynthesis and metabolism	hsa00514	Other types of O-glycan biosynthesis	1/66	49/9376	2.89919604205318	GALNT11	1.12222415844054
Human Diseases	Infectious disease: bacterial	hsa05110	Vibrio cholerae infection	1/66	51/9376	2.78550207961973	PLCG2	1.07647461681609
Cellular Processes	Cell growth and death	hsa04110	Cell cycle	2/66	158/9376	1.79823551975451	CCND1/CDKN1C	0.851969418676113
Organismal Systems	Endocrine system	hsa04913	Ovarian steroidogenesis	1/66	52/9376	2.73193473193473	HSD17B1	1.05442289288943
Metabolism	Amino acid metabolism	hsa00270	Cysteine and methionine metabolism	1/66	54/9376	2.6307519640853	LDHB	1.01184270830804
Environmental Information Processing	Signal transduction	hsa04022	cGMP-PKG signaling pathway	2/66	166/9376	1.71157356699525	ATP2B1/SLC25A5	0.77880153936135
Metabolism	Glycan biosynthesis and metabolism	hsa00510	N-Glycan biosynthesis	1/66	56/9376	2.53679653679654	TUSC3	0.971147498789242
Environmental Information Processing	Signal transduction	hsa04340	Hedgehog signaling pathway	1/66	56/9376	2.53679653679654	CCND1	0.971147498789242
Metabolism	Global and overview maps	hsa01212	Fatty acid metabolism	1/66	57/9376	2.4922913343966	ECHS1	0.951456975691979
Human Diseases	Cancer: specific types	hsa05213	Endometrial cancer	1/66	59/9376	2.40780688238315	CCND1	0.913300735882364
Organismal Systems	Aging	hsa04213	Longevity regulating pathway - multiple species	1/66	62/9376	2.29130009775171	HSPA1A	0.858890259123468
Metabolism	Amino acid metabolism	hsa00310	Lysine degradation	1/66	63/9376	2.25493025493025	ECHS1	0.841449057857294
Metabolism	Lipid metabolism	hsa00590	Arachidonic acid metabolism	1/66	63/9376	2.25493025493025	GPX4	0.841449057857294
Metabolism	Lipid metabolism	hsa00140	Steroid hormone biosynthesis	1/66	66/9376	2.1524334251607	HSD17B1	0.791035071361896
Human Diseases	Cancer: specific types	hsa05221	Acute myeloid leukemia	1/66	68/9376	2.08912655971479	CCND1	0.758904946446706
Organismal Systems	Immune system	hsa04664	Fc epsilon RI signaling pathway	1/66	69/9376	2.05884936319719	PLCG2	0.743252936381486
Organismal Systems	Endocrine system	hsa04917	Prolactin signaling pathway	1/66	71/9376	2.00085360648741	CCND1	0.71272880230442
Human Diseases	Infectious disease: bacterial	hsa05120	Epithelial cell signaling in Helicobacter pylori infection	1/66	71/9376	2.00085360648741	PLCG2	0.71272880230442
Human Diseases	Cancer: overview	hsa05230	Central carbon metabolism in cancer	1/66	71/9376	2.00085360648741	LDHB	0.71272880230442
Human Diseases	Cancer: overview	hsa05206	MicroRNAs in cancer	3/66	323/9376	1.31944835350408	PLCG2/CCND1/CD44	0.491913136485859
Genetic Information Processing	Information processing in viruses	hsa03250	Viral life cycle - HIV-1	1/66	73/9376	1.94603569946036	MLLT1	0.68318796972284
Human Diseases	Cancer: specific types	hsa05218	Melanoma	1/66	73/9376	1.94603569946036	CCND1	0.68318796972284
NA	NA	hsa04082	Neuroactive ligand signaling	2/66	199/9376	1.4277447845287	OGFRL1/GABRE	0.513503798772282
Cellular Processes	Cell growth and death	hsa04115	p53 signaling pathway	1/66	75/9376	1.89414141414141	CCND1	0.654568023510287
Organismal Systems	Endocrine system	hsa03320	PPAR signaling pathway	1/66	76/9376	1.86921850079745	SLC27A2	0.640585418640966
Human Diseases	Cancer: specific types	hsa05212	Pancreatic cancer	1/66	77/9376	1.84494293585203	CCND1	0.626812117442052
Human Diseases	Cancer: specific types	hsa05220	Chronic myeloid leukemia	1/66	77/9376	1.84494293585203	CCND1	0.626812117442052
Metabolism	Carbohydrate metabolism	hsa00562	Inositol phosphate metabolism	1/66	78/9376	1.82128982128982	PLCG2	0.613241781054214
Genetic Information Processing	Folding, sorting and degradation	hsa03018	RNA degradation	1/66	78/9376	1.82128982128982	HSPD1	0.613241781054214
Human Diseases	Cancer: overview	hsa05203	Viral carcinogenesis	2/66	205/9376	1.3859571322986	CCND1/HLA-C	0.470425028805235
Organismal Systems	Nervous system	hsa04721	Synaptic vesicle cycle	1/66	79/9376	1.79823551975451	AP2S1	0.599868344763565
Human Diseases	Drug resistance: antineoplastic	hsa01521	EGFR tyrosine kinase inhibitor resistance	1/66	80/9376	1.77575757575758	PLCG2	0.586686002770728
Genetic Information Processing	Chromosome	hsa03083	Polycomb repressive complex	1/66	83/9376	1.71157356699525	AUTS2	0.548231076570602
Cellular Processes	Transport and catabolism	hsa04146	Peroxisome	1/66	83/9376	1.71157356699525	SLC27A2	0.548231076570602
Human Diseases	Infectious disease: viral	hsa05170	Human immunodeficiency virus 1 infection	2/66	214/9376	1.32766921551968	PLCG2/HLA-C	0.408253719166846
Human Diseases	Cardiovascular disease	hsa05417	Lipid and atherosclerosis	2/66	216/9376	1.31537598204265	HSPA1A/HSPD1	0.394812159865668
Metabolism	Global and overview maps	hsa01232	Nucleotide metabolism	1/66	85/9376	1.67130124777184	PNP	0.523453915493191
Environmental Information Processing	Signal transduction	hsa04012	ErbB signaling pathway	1/66	86/9376	1.65186751233263	PLCG2	0.511309040256771
Organismal Systems	Circulatory system	hsa04260	Cardiac muscle contraction	1/66	87/9376	1.63288052943225	MT-CYB	0.499320785633147
Human Diseases	Cancer: specific types	hsa05210	Colorectal cancer	1/66	87/9376	1.63288052943225	CCND1	0.499320785633147
Genetic Information Processing	Translation	hsa03010	Ribosome	2/66	222/9376	1.27982527982528	RPS21/RPL3	0.355255446885713
Environmental Information Processing	Signaling molecules and interaction	hsa04512	ECM-receptor interaction	1/66	89/9376	1.59618658495063	CD44	0.475797598393923
Organismal Systems	Immune system	hsa04662	B cell receptor signaling pathway	1/66	91/9376	1.56110556110556	PLCG2	0.452852824265025
Human Diseases	Substance dependence	hsa05032	Morphine addiction	1/66	91/9376	1.56110556110556	GABRE	0.452852824265025
Human Diseases	Infectious disease: viral	hsa05163	Human cytomegalovirus infection	2/66	227/9376	1.25163529568816	CCND1/HLA-C	0.323132349029046
Organismal Systems	Digestive system	hsa04970	Salivary secretion	1/66	93/9376	1.52753339850114	ATP2B1	0.43045724802534
Human Diseases	Cancer: specific types	hsa05222	Small cell lung cancer	1/66	93/9376	1.52753339850114	CCND1	0.43045724802534
Organismal Systems	Immune system	hsa04657	IL-17 signaling pathway	1/66	94/9376	1.51128304319794	S100A9	0.419456858348605
Environmental Information Processing	Signal transduction	hsa04070	Phosphatidylinositol signaling system	1/66	98/9376	1.44959802102659	PLCG2	0.376697736121531
Organismal Systems	Immune system	hsa04666	Fc gamma R-mediated phagocytosis	1/66	98/9376	1.44959802102659	PLCG2	0.376697736121531
Organismal Systems	Endocrine system	hsa04925	Aldosterone synthesis and secretion	1/66	98/9376	1.44959802102659	ATP2B1	0.376697736121531
Human Diseases	Drug resistance: antineoplastic	hsa01522	Endocrine resistance	1/66	99/9376	1.4349556167738	CCND1	0.366303887647153
Organismal Systems	Sensory system	hsa04750	Inflammatory mediator regulation of TRP channels	1/66	99/9376	1.4349556167738	PLCG2	0.366303887647153
Genetic Information Processing	Transcription	hsa03040	Spliceosome	2/66	243/9376	1.16922309514902	CTNNBL1/HSPA1A	0.225029164461048
Organismal Systems	Digestive system	hsa04972	Pancreatic secretion	1/66	102/9376	1.39275103980986	ATP2B1	0.335789142238007
Metabolism	Lipid metabolism	hsa00564	Glycerophospholipid metabolism	1/66	104/9376	1.36596736596737	PISD	0.315976718032501
Environmental Information Processing	Signal transduction	hsa04064	NF-kappa B signaling pathway	1/66	105/9376	1.35295815295815	PLCG2	0.306222672620386
Cellular Processes	Transport and catabolism	hsa04137	Mitophagy - animal	1/66	105/9376	1.35295815295815	TOMM40	0.306222672620386
Organismal Systems	Immune system	hsa04625	C-type lectin receptor signaling pathway	1/66	105/9376	1.35295815295815	PLCG2	0.306222672620386
Cellular Processes	Transport and catabolism	hsa04142	Lysosome biogenesis	2/66	250/9376	1.13648484848485	MCOLN3/AP2S1	0.18416070954478
Human Diseases	Cancer: specific types	hsa05215	Prostate cancer	1/66	106/9376	1.34019439679817	CCND1	0.296567111516881
Organismal Systems	Endocrine system	hsa04922	Glucagon signaling pathway	1/66	107/9376	1.32766921551968	LDHB	0.287007902389122
Human Diseases	Infectious disease: bacterial	hsa05131	Shigellosis	2/66	253/9376	1.1230087435621	PLCG2/CD44	0.166997577480154
Human Diseases	Endocrine and metabolic disease	hsa04931	Insulin resistance	1/66	109/9376	1.30330831248262	SLC27A2	0.268170341908896
Organismal Systems	Endocrine system	hsa04928	Parathyroid hormone synthesis, secretion and action	1/66	115/9376	1.23530961791831	SLC34A2	0.213767866207927
Organismal Systems	Immune system	hsa04670	Leukocyte transendothelial migration	1/66	116/9376	1.22466039707419	PLCG2	0.204990053548741
Organismal Systems	Nervous system	hsa04724	Glutamatergic synapse	1/66	116/9376	1.22466039707419	GLUL	0.204990053548741
Organismal Systems	Nervous system	hsa04722	Neurotrophin signaling pathway	1/66	120/9376	1.18383838383838	PLCG2	0.170646705774983
Environmental Information Processing	Signal transduction	hsa04152	AMPK signaling pathway	1/66	122/9376	1.16443119721808	CCND1	0.153915427217417
Organismal Systems	Endocrine system	hsa04935	Growth hormone synthesis, secretion and action	1/66	122/9376	1.16443119721808	PLCG2	0.153915427217417
Organismal Systems	Immune system	hsa04611	Platelet activation	1/66	126/9376	1.12746512746513	PLCG2	0.12127982350568
Metabolism	Nucleotide metabolism	hsa00230	Purine metabolism	1/66	128/9376	1.10984848484848	PNP	0.105355669391366
Environmental Information Processing	Signal transduction	hsa04068	FoxO signaling pathway	1/66	133/9376	1.06812485759854	CCND1	0.0666204737827727
NA	NA	hsa04517	IgSF CAM signaling	2/66	299/9376	0.950238167629472	PLCG2/NRP2	-0.0736280936164423
Organismal Systems	Endocrine system	hsa04915	Estrogen signaling pathway	1/66	139/9376	1.02201874863745	HSPA1A	0.0220200006495392
Environmental Information Processing	Signal transduction	hsa04010	MAPK signaling pathway	2/66	300/9376	0.947070707070707	HSPA1A/HSPB1	-0.0784498724150372
Organismal Systems	Development and regeneration	hsa04380	Osteoclast differentiation	1/66	142/9376	1.0004268032437	PLCG2	0.000431479050103631
Human Diseases	Neurodegenerative disease	hsa05017	Spinocerebellar ataxia	1/66	144/9376	0.986531986531987	SLC25A5	-0.0137125951981139
Human Diseases	Cancer: specific types	hsa05224	Breast cancer	1/66	148/9376	0.95986895986896	CCND1	-0.0414324148355297
Environmental Information Processing	Signal transduction	hsa04072	Phospholipase D signaling pathway	1/66	149/9376	0.953426886312792	PLCG2	-0.0482481775267277
Human Diseases	Cancer: specific types	hsa05226	Gastric cancer	1/66	150/9376	0.947070707070707	CCND1	-0.0550196422594877
Organismal Systems	Circulatory system	hsa04261	Adrenergic signaling in cardiomyocytes	1/66	154/9376	0.922471467926013	ATP2B1	-0.0816755613569222
NA	NA	hsa04518	Integrin signaling	1/66	154/9376	0.922471467926013	CCND1	-0.0816755613569222
Organismal Systems	Endocrine system	hsa04921	Oxytocin signaling pathway	1/66	154/9376	0.922471467926013	CCND1	-0.0816755613569222
Human Diseases	Endocrine and metabolic disease	hsa04934	Cushing syndrome	1/66	155/9376	0.916520039100684	CCND1	-0.0882351931128194
Human Diseases	Infectious disease: viral	hsa05160	Hepatitis C	1/66	156/9376	0.910644910644911	CCND1	-0.0947542934503123
Environmental Information Processing	Signal transduction	hsa04390	Hippo signaling pathway	1/66	157/9376	0.904844624589847	CCND1	-0.101233443819278
Human Diseases	Endocrine and metabolic disease	hsa04932	Non-alcoholic fatty liver disease	1/66	157/9376	0.904844624589847	MT-CYB	-0.101233443819278
Human Diseases	Infectious disease: viral	hsa05165	Human papillomavirus infection	2/66	333/9376	0.853216853216853	CCND1/HLA-C	-0.229627982857785
Environmental Information Processing	Signal transduction	hsa04630	JAK-STAT signaling pathway	1/66	168/9376	0.845598845598845	CCND1	-0.170022067942485
Cellular Processes	Transport and catabolism	hsa04140	Autophagy - animal	1/66	169/9376	0.840595302133764	HMGB1	-0.176063026354503
Cellular Processes	Cellular community - eukaryotes	hsa04530	Tight junction	1/66	170/9376	0.835650623885918	CCND1	-0.182070590479387
Organismal Systems	Development and regeneration	hsa04360	Axon guidance	1/66	184/9376	0.772068511198946	PLCG2	-0.262900248357964
Organismal Systems	Immune system	hsa04621	NOD-like receptor signaling pathway	1/66	187/9376	0.759682385350834	TXNIP	-0.279482775554414
Environmental Information Processing	Signaling molecules and interaction	hsa04080	Neuroactive ligand-receptor interaction	2/66	370/9376	0.767895167895168	OGFRL1/GABRE	-0.383532205767037
Organismal Systems	Immune system	hsa04062	Chemokine signaling pathway	1/66	193/9376	0.736065316376197	PLCG2	-0.311936067190817
Human Diseases	Cancer: overview	hsa05202	Transcriptional misregulation in cancer	1/66	201/9376	0.706769184381125	MLLT1	-0.353824063693368
Cellular Processes	Cellular community - eukaryotes	hsa04510	Focal adhesion	1/66	203/9376	0.699805941185252	CCND1	-0.364063533980992
NA	NA	hsa04382	Cornified envelope formation	1/66	217/9376	0.654657170786203	S100A9	-0.433350244098305
Environmental Information Processing	Signal transduction	hsa04024	cAMP signaling pathway	1/66	226/9376	0.628586752480558	ATP2B1	-0.475865070743492
Cellular Processes	Cell motility	hsa04810	Regulation of actin cytoskeleton	1/66	232/9376	0.612330198537095	IQGAP2	-0.503408588997586
Cellular Processes	Cell motility	hsa04820	Cytoskeleton in muscle cells	1/66	233/9376	0.609702171933932	FBN2	-0.507940100582911
Environmental Information Processing	Signal transduction	hsa04014	Ras signaling pathway	1/66	238/9376	0.596893302775656	PLCG2	-0.530353794882487
Environmental Information Processing	Signal transduction	hsa04151	PI3K-Akt signaling pathway	1/66	362/9376	0.392432613427089	CCND1	-0.992596472200765
NA	NA	hsa04519	Cadherin signaling	1/66	404/9376	0.351635163516352	GABRE	-1.12162651870433