category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Organismal Systems	Aging	hsa04213	Longevity regulating pathway - multiple species	2/19	62/9376	15.918505942275	SOD1/CAT	5.31064392808126
Human Diseases	Cancer: overview	hsa05208	Chemical carcinogenesis - reactive oxygen species	3/19	227/9376	6.52167864595409	SOD1/MT-CYB/CAT	3.79482162213389
Cellular Processes	Transport and catabolism	hsa04146	Peroxisome	2/19	83/9376	11.8909321496512	SOD1/CAT	4.49076422198034
Metabolism	Global and overview maps	hsa01232	Nucleotide metabolism	2/19	85/9376	11.6111455108359	NT5E/AK8	4.42827544542905
Organismal Systems	Circulatory system	hsa04260	Cardiac muscle contraction	2/19	87/9376	11.3442226255293	ATP1A4/MT-CYB	4.36784408694871
Organismal Systems	Immune system	hsa04666	Fc gamma R-mediated phagocytosis	2/19	98/9376	10.0708915145005	PLCG2/ARPC5	4.0675223749633
Organismal Systems	Sensory system	hsa04750	Inflammatory mediator regulation of TRP channels	2/19	99/9376	9.96916533758639	HTR2C/PLCG2	4.04259256396517
NA	NA	hsa04517	IgSF CAM signaling	3/19	299/9376	4.95124097870093	NRCAM/PLCG2/ARPC5	3.12890276941357
Organismal Systems	Endocrine system	hsa04919	Thyroid hormone signaling pathway	2/19	122/9376	8.08973252804142	ATP1A4/PLCG2	3.55172345012551
Metabolism	Nucleotide metabolism	hsa00230	Purine metabolism	2/19	128/9376	7.71052631578947	NT5E/AK8	3.44454435941509
Metabolism	Metabolism of cofactors and vitamins	hsa00730	Thiamine metabolism	1/19	15/9376	32.8982456140351	AK8	5.57115739993347
Human Diseases	Neurodegenerative disease	hsa05014	Amyotrophic lateral sclerosis	3/19	368/9376	4.02288329519451	SOD1/MT-CYB/CAT	2.66578564603389
Organismal Systems	Excretory system	hsa04964	Proximal tubule bicarbonate reclamation	1/19	23/9376	21.4553775743707	ATP1A4	4.42578258019393
Metabolism	Carbohydrate metabolism	hsa00630	Glyoxylate and dicarboxylate metabolism	1/19	31/9376	15.918505942275	CAT	3.74895864408232
Human Diseases	Cancer: overview	hsa05205	Proteoglycans in cancer	2/19	204/9376	4.83797729618163	PLCG2/TWIST2	2.49735099807924
Human Diseases	Neurodegenerative disease	hsa05022	Pathways of neurodegeneration - multiple diseases	3/19	480/9376	3.08421052631579	SOD1/MT-CYB/CAT	2.11231625200006
Metabolism	Metabolism of cofactors and vitamins	hsa00760	Nicotinate and nicotinamide metabolism	1/19	38/9376	12.9861495844875	NT5E	3.33609708521038
Organismal Systems	Excretory system	hsa04960	Aldosterone-regulated sodium reabsorption	1/19	38/9376	12.9861495844875	ATP1A4	3.33609708521038
Metabolism	Amino acid metabolism	hsa00380	Tryptophan metabolism	1/19	42/9376	11.749373433584	CAT	3.1460673919501
Environmental Information Processing	Membrane transport	hsa02010	ABC transporters	1/19	45/9376	10.966081871345	ABCG1	3.01967870762622
Human Diseases	Infectious disease: bacterial	hsa05131	Shigellosis	2/19	253/9376	3.90097774079467	PLCG2/ARPC5	2.10780263729265
Environmental Information Processing	Signal transduction	hsa04020	Calcium signaling pathway	2/19	254/9376	3.88561956071281	HTR2C/PLCG2	2.10089826089269
Organismal Systems	Digestive system	hsa04973	Carbohydrate digestion and absorption	1/19	48/9376	10.280701754386	ATP1A4	2.90470003717941
Human Diseases	Infectious disease: bacterial	hsa05110	Vibrio cholerae infection	1/19	51/9376	9.67595459236326	PLCG2	2.79944579075055
Human Diseases	Neurodegenerative disease	hsa05012	Parkinson disease	2/19	268/9376	3.68263943440691	SOD1/MT-CYB	2.0077623886372
Organismal Systems	Excretory system	hsa04961	Endocrine and other factor-regulated calcium reabsorption	1/19	53/9376	9.31082423038729	ATP1A4	2.73399876424551
Human Diseases	Neurodegenerative disease	hsa05020	Prion disease	2/19	275/9376	3.5888995215311	SOD1/MT-CYB	1.96350091917235
Metabolism	Nucleotide metabolism	hsa00240	Pyrimidine metabolism	1/19	59/9376	8.36396074933096	NT5E	2.55678109837479
Environmental Information Processing	Signal transduction	hsa04370	VEGF signaling pathway	1/19	60/9376	8.22456140350877	PLCG2	2.52968529261772
Organismal Systems	Digestive system	hsa04978	Mineral absorption	1/19	61/9376	8.08973252804142	ATP1A4	2.50321102449827
Environmental Information Processing	Signaling molecules and interaction	hsa04060	Cytokine-cytokine receptor interaction	2/19	298/9376	3.31190392087602	IL1RL1/IL13RA2	1.82758232104215
Human Diseases	Neurodegenerative disease	hsa05016	Huntington disease	2/19	308/9376	3.20437457279563	SOD1/MT-CYB	1.77255254977317
Organismal Systems	Immune system	hsa04664	Fc epsilon RI signaling pathway	1/19	69/9376	7.15179252479024	PLCG2	2.31108273082914
Human Diseases	Infectious disease: bacterial	hsa05120	Epithelial cell signaling in Helicobacter pylori infection	1/19	71/9376	6.95033358042995	PLCG2	2.26780873040109
Human Diseases	Cancer: specific types	hsa05223	Non-small cell lung cancer	1/19	73/9376	6.75991348233598	PLCG2	2.22617859996441
Organismal Systems	Endocrine system	hsa04918	Thyroid hormone synthesis	1/19	75/9376	6.57964912280702	ATP1A4	2.18608388379795
Organismal Systems	Digestive system	hsa04971	Gastric acid secretion	1/19	76/9376	6.49307479224377	ATP1A4	2.16658113895086
Human Diseases	Cancer: specific types	hsa05214	Glioma	1/19	76/9376	6.49307479224377	PLCG2	2.16658113895086
Metabolism	Carbohydrate metabolism	hsa00562	Inositol phosphate metabolism	1/19	78/9376	6.32658569500675	PLCG2	2.12860742526379
Human Diseases	Infectious disease: bacterial	hsa05100	Bacterial invasion of epithelial cells	1/19	78/9376	6.32658569500675	ARPC5	2.12860742526379
Human Diseases	Drug resistance: antineoplastic	hsa01521	EGFR tyrosine kinase inhibitor resistance	1/19	80/9376	6.16842105263158	PLCG2	2.09193866376665
Environmental Information Processing	Signal transduction	hsa04012	ErbB signaling pathway	1/19	86/9376	5.73806609547124	PLCG2	1.98900835467916
Organismal Systems	Endocrine system	hsa04911	Insulin secretion	1/19	86/9376	5.73806609547124	ATP1A4	1.98900835467916
Cellular Processes	Cellular community - eukaryotes	hsa04540	Gap junction	1/19	89/9376	5.54464813719692	HTR2C	1.94111680169438
Organismal Systems	Aging	hsa04211	Longevity regulating pathway	1/19	90/9376	5.48304093567251	CAT	1.92563399137024
Organismal Systems	Digestive system	hsa04976	Bile secretion	1/19	90/9376	5.48304093567251	ATP1A4	1.92563399137024
Organismal Systems	Immune system	hsa04662	B cell receptor signaling pathway	1/19	91/9376	5.42278773857721	PLCG2	1.91038088057249
Organismal Systems	Digestive system	hsa04970	Salivary secretion	1/19	93/9376	5.30616864742501	ATP1A4	1.88053948935344
Environmental Information Processing	Signal transduction	hsa04070	Phosphatidylinositol signaling system	1/19	98/9376	5.03544575725027	PLCG2	1.80955376704998
Organismal Systems	Endocrine system	hsa04925	Aldosterone synthesis and secretion	1/19	98/9376	5.03544575725027	ATP1A4	1.80955376704998
Human Diseases	Endocrine and metabolic disease	hsa04933	AGE-RAGE signaling pathway in diabetic complications	1/19	101/9376	4.88587806149036	PLCG2	1.76924110177362
Organismal Systems	Digestive system	hsa04972	Pancreatic secretion	1/19	102/9376	4.83797729618163	ATP1A4	1.75615589292625
Organismal Systems	Digestive system	hsa04974	Protein digestion and absorption	1/19	103/9376	4.79100664282064	ATP1A4	1.74323987654735
Environmental Information Processing	Signal transduction	hsa04064	NF-kappa B signaling pathway	1/19	105/9376	4.69974937343358	PLCG2	1.71789963827157
Organismal Systems	Immune system	hsa04625	C-type lectin receptor signaling pathway	1/19	105/9376	4.69974937343358	PLCG2	1.71789963827157
NA	NA	hsa04519	Cadherin signaling	2/19	404/9376	2.44293903074518	KRT7/ARPC5	1.33594369623319
Environmental Information Processing	Signal transduction	hsa04066	HIF-1 signaling pathway	1/19	110/9376	4.48612440191388	PLCG2	1.65724683920097
Environmental Information Processing	Signal transduction	hsa04350	TGF-beta signaling pathway	1/19	110/9376	4.48612440191388	FST	1.65724683920097
Organismal Systems	Nervous system	hsa04726	Serotonergic synapse	1/19	115/9376	4.29107551487414	HTR2C	1.60011777439542
Organismal Systems	Endocrine system	hsa04928	Parathyroid hormone synthesis, secretion and action	1/19	115/9376	4.29107551487414	GCM1	1.60011777439542
Metabolism	Global and overview maps	hsa01200	Carbon metabolism	1/19	116/9376	4.2540834845735	CAT	1.58908202787866
Organismal Systems	Immune system	hsa04670	Leukocyte transendothelial migration	1/19	116/9376	4.2540834845735	PLCG2	1.58908202787866
Organismal Systems	Nervous system	hsa04722	Neurotrophin signaling pathway	1/19	120/9376	4.11228070175439	PLCG2	1.5461507441955
Organismal Systems	Endocrine system	hsa04935	Growth hormone synthesis, secretion and action	1/19	122/9376	4.04486626402071	PLCG2	1.52537812528818
Organismal Systems	Immune system	hsa04611	Platelet activation	1/19	126/9376	3.91645781119465	PLCG2	1.48512917073856
Environmental Information Processing	Signal transduction	hsa04068	FoxO signaling pathway	1/19	133/9376	3.71032845271072	CAT	1.41851976748277
Organismal Systems	Immune system	hsa04650	Natural killer cell mediated cytotoxicity	1/19	133/9376	3.71032845271072	PLCG2	1.41851976748277
Metabolism	Energy metabolism	hsa00190	Oxidative phosphorylation	1/19	138/9376	3.57589626239512	MT-CYB	1.37364040568199
Human Diseases	Infectious disease: bacterial	hsa05135	Yersinia infection	1/19	138/9376	3.57589626239512	ARPC5	1.37364040568199
Organismal Systems	Development and regeneration	hsa04380	Osteoclast differentiation	1/19	142/9376	3.47516679021497	PLCG2	1.33920736912169
Environmental Information Processing	Signal transduction	hsa04072	Phospholipase D signaling pathway	1/19	149/9376	3.31190392087602	PLCG2	1.28181922034048
Metabolism	Global and overview maps	hsa01240	Biosynthesis of cofactors	1/19	154/9376	3.20437457279563	AK8	1.24287461605075
Organismal Systems	Circulatory system	hsa04261	Adrenergic signaling in cardiomyocytes	1/19	154/9376	3.20437457279563	ATP1A4	1.24287461605075
Human Diseases	Endocrine and metabolic disease	hsa04932	Non-alcoholic fatty liver disease	1/19	157/9376	3.14314448541736	MT-CYB	1.22026314229297
Environmental Information Processing	Signaling molecules and interaction	hsa04514	Cell adhesion molecule (CAM) interaction	1/19	160/9376	3.08421052631579	NRCAM	1.19818662449611
Environmental Information Processing	Signal transduction	hsa04022	cGMP-PKG signaling pathway	1/19	166/9376	2.97273303741281	ATP1A4	1.15554448890113
Environmental Information Processing	Signal transduction	hsa04630	JAK-STAT signaling pathway	1/19	168/9376	2.93734335839599	IL13RA2	1.14175443625532
Cellular Processes	Cellular community - eukaryotes	hsa04530	Tight junction	1/19	170/9376	2.90278637770898	ARPC5	1.12816632694913
Human Diseases	Cancer: specific types	hsa05225	Hepatocellular carcinoma	1/19	170/9376	2.90278637770898	PLCG2	1.12816632694913
Environmental Information Processing	Signal transduction	hsa04310	Wnt signaling pathway	1/19	178/9376	2.77232406859846	SERPINF1	1.07572325626465
Organismal Systems	Development and regeneration	hsa04360	Axon guidance	1/19	184/9376	2.68192219679634	PLCG2	1.03825475726543
Organismal Systems	Immune system	hsa04621	NOD-like receptor signaling pathway	1/19	187/9376	2.63889670700816	TXNIP	1.02007565779835
Organismal Systems	Immune system	hsa04062	Chemokine signaling pathway	1/19	193/9376	2.55685846741205	PLCG2	0.984758230608679
Organismal Systems	Immune system	hsa04613	Neutrophil extracellular trap formation	1/19	195/9376	2.5306342780027	PLCG2	0.973280160852223
Human Diseases	Infectious disease: viral	hsa05167	Kaposi sarcoma-associated herpesvirus infection	1/19	196/9376	2.51772287862513	PLCG2	0.967594296814322
NA	NA	hsa04082	Neuroactive ligand signaling	1/19	199/9376	2.47976725733933	HTR2C	0.950744254964229
Human Diseases	Infectious disease: bacterial	hsa05130	Pathogenic Escherichia coli infection	1/19	200/9376	2.46736842105263	ARPC5	0.945195374797285
Human Diseases	Infectious disease: viral	hsa05169	Epstein-Barr virus infection	1/19	205/9376	2.40718870346598	PLCG2	0.917941591131371
Human Diseases	Cardiovascular disease	hsa05415	Diabetic cardiomyopathy	1/19	205/9376	2.40718870346598	MT-CYB	0.917941591131371
Human Diseases	Infectious disease: viral	hsa05170	Human immunodeficiency virus 1 infection	1/19	214/9376	2.30595179537629	PLCG2	0.870829261393262
Human Diseases	Cardiovascular disease	hsa05417	Lipid and atherosclerosis	1/19	216/9376	2.28460038986355	ABCG1	0.860679209208602
NA	NA	hsa04382	Cornified envelope formation	1/19	217/9376	2.27407227746786	KRT7	0.855645808727713
Environmental Information Processing	Signal transduction	hsa04024	cAMP signaling pathway	1/19	226/9376	2.18351187703773	ATP1A4	0.811540909017803
Cellular Processes	Cell motility	hsa04810	Regulation of actin cytoskeleton	1/19	232/9376	2.12704174228675	ARPC5	0.783267323637921
Cellular Processes	Cell motility	hsa04820	Cytoskeleton in muscle cells	1/19	233/9376	2.1179128077705	ATP1A4	0.778638110358914
Organismal Systems	Environmental adaptation	hsa04714	Thermogenesis	1/19	235/9376	2.09988801791713	MT-CYB	0.769448702254928
Environmental Information Processing	Signal transduction	hsa04014	Ras signaling pathway	1/19	238/9376	2.0734188412207	PLCG2	0.755833678936908
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	1/19	238/9376	2.0734188412207	PLCG2	0.755833678936908
Human Diseases	Infectious disease: bacterial	hsa05132	Salmonella infection	1/19	248/9376	1.98981324278438	ARPC5	0.711844950365709
Cellular Processes	Transport and catabolism	hsa04144	Endocytosis	1/19	250/9376	1.97389473684211	ARPC5	0.70329238469679
Human Diseases	Cancer: overview	hsa05206	MicroRNAs in cancer	1/19	323/9376	1.52778230405736	PLCG2	0.434964636770031
Environmental Information Processing	Signaling molecules and interaction	hsa04080	Neuroactive ligand-receptor interaction	1/19	370/9376	1.33371266002845	HTR2C	0.29512207613382
Human Diseases	Neurodegenerative disease	hsa05010	Alzheimer disease	1/19	388/9376	1.27183939229517	MT-CYB	0.246428450065149