category subcategory ID Description GeneRatio BgRatio FoldEnrichment geneName zScore Metabolism Energy metabolism hsa00190 Oxidative phosphorylation 12/152 138/9376 5.36384439359268 MT-ATP8/MT-CYB/MT-ND5/MT-ND4L/ATP6V0B/MT-ND6/MT-ND1/MT-ATP6/COX4I1/NDUFA10/MT-CO2/MT-ND2 6.62929896931782 Human Diseases Cancer: overview hsa05208 Chemical carcinogenesis - reactive oxygen species 14/152 227/9376 3.80431254347322 MT-ATP8/SLC26A2/MT-CYB/EGFR/MT-ND5/GSTA3/MT-ND4L/MT-ND6/MT-ND1/MT-ATP6/COX4I1/NDUFA10/MT-CO2/MT-ND2 5.49035358464519 Genetic Information Processing Folding, sorting and degradation hsa04141 Protein processing in endoplasmic reticulum 12/152 174/9376 4.2540834845735 TUSC3/RRBP1/PDIA3/LMAN1/HSPA1A/ERP29/UBXN4/LMAN2/HSP90B1/CALR/CANX/SIL1 5.5617310713317 Human Diseases Neurodegenerative disease hsa05020 Prion disease 15/152 275/9376 3.36459330143541 MT-ATP8/MT-CYB/MT-ND5/MT-ND4L/HSPA1A/MT-ND6/MT-ND1/MT-ATP6/COX4I1/NDUFA10/MT-CO2/TUBB4B/MT-ND2/C1QA/EGR1 5.10888385665363 Human Diseases Neurodegenerative disease hsa05012 Parkinson disease 14/152 268/9376 3.22230950510605 MT-ATP8/MT-CYB/MT-ND5/MT-ND4L/UBB/MT-ND6/MT-ND1/MT-ATP6/COX4I1/NDUFA10/MT-CO2/TUBB4B/MT-ND2/SLC39A7 4.73814355665339 Organismal Systems Environmental adaptation hsa04714 Thermogenesis 13/152 235/9376 3.41231802911534 MT-ATP8/MT-CYB/MT-ND5/MT-ND4L/MT-ND6/MT-ND1/COX19/MT-ATP6/ADCY2/COX4I1/NDUFA10/MT-CO2/MT-ND2 4.80750145509845 Human Diseases Cardiovascular disease hsa05415 Diabetic cardiomyopathy 12/152 205/9376 3.61078305519897 MT-ATP8/MT-CYB/MT-ND5/MT-ND4L/MT-ND6/MT-ND1/PRKCZ/MT-ATP6/COX4I1/NDUFA10/MT-CO2/MT-ND2 4.85162420562152 Organismal Systems Digestive system hsa04970 Salivary secretion 8/152 93/9376 5.30616864742501 ATP2B1/ATP1A4/KCNN4/VAMP2/ATP1B3/CST3/ADCY2/ADRB1 5.35717851804958 Human Diseases Neurodegenerative disease hsa05016 Huntington disease 14/152 308/9376 2.80382775119617 MT-ATP8/MT-CYB/MT-ND5/MT-ND4L/MT-ND6/MT-ND1/MT-ATP6/COX4I1/POLR2J3/NDUFA10/MT-CO2/AP2S1/TUBB4B/MT-ND2 4.13202034918686 NA NA hsa04518 Integrin signaling 9/152 154/9376 3.60492139439508 EGFR/FBN1/ITGB4/ITGB1/ITGAV/CCND2/LAMB4/ITGB8/CDH1 4.18398586974626 Organismal Systems Endocrine system hsa04918 Thyroid hormone synthesis 6/152 75/9376 4.93473684210526 ATP1A4/ATP1B3/CGA/ADCY2/HSP90B1/CANX 4.39166582863365 Organismal Systems Digestive system hsa04974 Protein digestion and absorption 7/152 103/9376 4.19213081246806 COL14A1/ATP1A4/KCNN4/ATP1B3/SLC3A2/COL21A1/MME 4.18154666513449 Cellular Processes Cell motility hsa04820 Cytoskeleton in muscle cells 11/152 233/9376 2.91213011068444 FBN2/FBN1/ITGB4/ATP1A4/ITGB1/ITGAV/DIAPH2/ATP1B3/SYNE2/CSRP2/ITGB8 3.79401310029071 Human Diseases Neurodegenerative disease hsa05010 Alzheimer disease 15/152 388/9376 2.38469886055345 MT-ATP8/MT-CYB/MT-ND5/APP/MT-ND4L/MT-ND6/MT-ND1/MT-ATP6/COX4I1/MME/NDUFA10/MT-CO2/TUBB4B/MT-ND2/SLC39A7 3.57591717189721 Environmental Information Processing Signaling molecules and interaction hsa04512 ECM-receptor interaction 6/152 89/9376 4.15848610289769 CD44/ITGB4/ITGB1/ITGAV/LAMB4/ITGB8 3.84312080162518 NA NA hsa04517 IgSF CAM signaling 12/152 299/9376 2.47562048935047 PLCG2/ITGB1/EPB41L3/NRP2/APP/RASA1/VAV3/NRCAM/TUBB4B/SORBS1/CD86/CDH1 3.32879375748778 Cellular Processes Transport and catabolism hsa04145 Phagosome 8/152 155/9376 3.18370118845501 ITGB1/ITGAV/ATP6V0B/HLA-DRA/CALR/TUBB4B/CANX/COLEC12 3.51898838650197 Environmental Information Processing Signaling molecules and interaction hsa04514 Cell adhesion molecule (CAM) interaction 8/152 160/9376 3.08421052631579 ITGB1/ITGAV/HLA-DRA/NRCAM/ITGB8/GLG1/CD86/CDH1 3.41332882489579 Cellular Processes Cell growth and death hsa04216 Ferroptosis 4/152 42/9376 5.87468671679198 SLC40A1/SLC3A2/LPCAT3/GPX4 4.06429517758145 Human Diseases Cardiovascular disease hsa05414 Dilated cardiomyopathy 6/152 105/9376 3.52481203007519 ITGB4/ITGB1/ITGAV/ADCY2/ADRB1/ITGB8 3.33970567739369 Organismal Systems Excretory system hsa04961 Endocrine and other factor-regulated calcium reabsorption 4/152 53/9376 4.65541211519364 ATP2B1/ATP1A4/ATP1B3/AP2S1 3.42565974744821 Organismal Systems Immune system hsa04612 Antigen processing and presentation 5/152 82/9376 3.7612323491656 PDIA3/HSPA1A/HLA-DRA/CALR/CANX 3.22371269775719 Organismal Systems Nervous system hsa04723 Retrograde endocannabinoid signaling 7/152 149/9376 2.89791593076651 MT-ND5/MT-ND4L/MT-ND6/MT-ND1/ADCY2/NDUFA10/MT-ND2 2.99769628796871 Organismal Systems Endocrine system hsa04911 Insulin secretion 5/152 86/9376 3.58629130966952 ATP1A4/KCNN4/VAMP2/ATP1B3/ADCY2 3.09290509628919 Cellular Processes Cell motility hsa04810 Regulation of actin cytoskeleton 9/152 232/9376 2.3929219600726 EGFR/ITGB4/ITGB1/ITGAV/DIAPH2/VAV3/WASF2/IQGAP2/ITGB8 2.75772181154021 Organismal Systems Circulatory system hsa04260 Cardiac muscle contraction 5/152 87/9376 3.54506957047792 MT-CYB/ATP1A4/ATP1B3/COX4I1/MT-CO2 3.06141769676638 Metabolism Carbohydrate metabolism hsa00640 Propanoate metabolism 3/152 32/9376 5.78289473684211 ACSS1/HADHA/LDHB 3.47894195076455 Human Diseases Neurodegenerative disease hsa05014 Amyotrophic lateral sclerosis 12/152 368/9376 2.01144164759725 MT-ATP8/MT-CYB/MT-ND5/MT-ND4L/MT-ND6/MT-ND1/MT-ATP6/COX4I1/NDUFA10/MT-CO2/TUBB4B/MT-ND2 2.54096298147435 Organismal Systems Digestive system hsa04978 Mineral absorption 4/152 61/9376 4.04486626402071 ATP2B1/ATP1A4/SLC40A1/ATP1B3 3.06259447928062 Cellular Processes Cellular community - eukaryotes hsa04510 Focal adhesion 8/152 203/9376 2.43090484832772 EGFR/ITGB4/ITGB1/ITGAV/CCND2/VAV3/LAMB4/ITGB8 2.64576253525888 Organismal Systems Immune system hsa04640 Hematopoietic cell lineage 5/152 100/9376 3.08421052631579 CD44/CSF3R/HLA-DRA/CD59/MME 2.68973193913295 Human Diseases Neurodegenerative disease hsa05022 Pathways of neurodegeneration - multiple diseases 14/152 480/9376 1.79912280701754 MT-ATP8/MT-CYB/MT-ND5/APP/MT-ND4L/UBB/MT-ND6/MT-ND1/MT-ATP6/COX4I1/NDUFA10/MT-CO2/TUBB4B/MT-ND2 2.30719627695905 Organismal Systems Digestive system hsa04972 Pancreatic secretion 5/152 102/9376 3.02373581011352 ATP2B1/ATP1A4/ATP1B3/PLA2G2A/ADCY2 2.63795961000962 Metabolism Lipid metabolism hsa00564 Glycerophospholipid metabolism 5/152 104/9376 2.96558704453441 PISD/LPIN2/PLA2G2A/PLPP3/LPCAT3 2.58743842972313 Organismal Systems Development and regeneration hsa04360 Axon guidance 7/152 184/9376 2.3466819221968 PLCG2/ITGB1/PLXNB2/RASA1/SEMA6A/PRKCZ/EPHB4 2.36819095964635 Human Diseases Endocrine and metabolic disease hsa04940 Type I diabetes mellitus 3/152 44/9376 4.20574162679426 HLA-DRA/HSPD1/CD86 2.73599484515203 Organismal Systems Endocrine system hsa04928 Parathyroid hormone synthesis, secretion and action 5/152 115/9376 2.68192219679634 EGFR/AKAP13/ADCY2/JUND/EGR1 2.32955873746871 Environmental Information Processing Signal transduction hsa04390 Hippo signaling pathway 6/152 157/9376 2.35735836406302 DLG5/AMOT/CCND2/PRKCZ/FRMD6/CDH1 2.2016598731134 Metabolism Amino acid metabolism hsa00330 Arginine and proline metabolism 3/152 50/9376 3.70105263157895 CKMT1A/SMS/CKMT1B 2.45820517373028 Human Diseases Cancer: overview hsa05205 Proteoglycans in cancer 7/152 204/9376 2.11661506707946 PLCG2/CD44/EGFR/ITGB1/ITGAV/VAV3/PDCD4 2.06982834209984 Human Diseases Infectious disease: viral hsa05169 Epstein-Barr virus infection 7/152 205/9376 2.10629011553273 PLCG2/CD44/GADD45G/CCND2/PDIA3/HLA-DRA/CALR 2.05582148707082 Human Diseases Cardiovascular disease hsa05412 Arrhythmogenic right ventricular cardiomyopathy 4/152 86/9376 2.86903304773562 ITGB4/ITGB1/ITGAV/ITGB8 2.23514722292172 Organismal Systems Endocrine system hsa04913 Ovarian steroidogenesis 3/152 52/9376 3.5587044534413 HSD17B1/CGA/ADCY2 2.37502644366597 Organismal Systems Excretory system hsa04964 Proximal tubule bicarbonate reclamation 2/152 23/9376 5.36384439359268 ATP1A4/ATP1B3 2.68971021251234 Organismal Systems Immune system hsa04610 Complement and coagulation cascades 4/152 88/9376 2.80382775119617 CD46/F5/CD59/C1QA 2.18234336141939 Cellular Processes Cellular community - eukaryotes hsa04540 Gap junction 4/152 89/9376 2.77232406859846 EGFR/ADCY2/ADRB1/TUBB4B 2.15649373571815 Metabolism Amino acid metabolism hsa00270 Cysteine and methionine metabolism 3/152 54/9376 3.42690058479532 SMS/DNMT3A/LDHB 2.29584255709394 Human Diseases Immune disease hsa05320 Autoimmune thyroid disease 3/152 54/9376 3.42690058479532 HLA-DRA/CGA/CD86 2.29584255709394 Cellular Processes Cellular community - eukaryotes hsa04520 Adherens junction 4/152 93/9376 2.65308432371251 EGFR/WASF2/SORBS1/CDH1 2.05655387714849 Organismal Systems Endocrine system hsa04912 GnRH signaling pathway 4/152 93/9376 2.65308432371251 EGFR/CGA/ADCY2/EGR1 2.05655387714849 Human Diseases Cancer: specific types hsa05222 Small cell lung cancer 4/152 93/9376 2.65308432371251 GADD45G/ITGB1/ITGAV/LAMB4 2.05655387714849 Metabolism Metabolism of other amino acids hsa00480 Glutathione metabolism 3/152 59/9376 3.13648528099911 GSTA3/SMS/GPX4 2.11317589604947 Organismal Systems Endocrine system hsa04923 Regulation of lipolysis in adipocytes 3/152 59/9376 3.13648528099911 CGA/ADCY2/ADRB1 2.11317589604947 Human Diseases Cancer: specific types hsa05213 Endometrial cancer 3/152 59/9376 3.13648528099911 EGFR/GADD45G/CDH1 2.11317589604947 Environmental Information Processing Signal transduction hsa04024 cAMP signaling pathway 7/152 226/9376 1.91057289240801 ATP2B1/ATP1A4/ATP1B3/VAV3/CGA/ADCY2/ADRB1 1.77871421099953 Organismal Systems Immune system hsa04666 Fc gamma R-mediated phagocytosis 4/152 98/9376 2.51772287862513 PLCG2/PLPP3/VAV3/WASF2 1.93876923529941 Organismal Systems Endocrine system hsa04925 Aldosterone synthesis and secretion 4/152 98/9376 2.51772287862513 ATP2B1/ATP1A4/ATP1B3/ADCY2 1.93876923529941 Organismal Systems Endocrine system hsa04915 Estrogen signaling pathway 5/152 139/9376 2.21885649375237 EGFR/HSPA1A/KRT23/ADCY2/HSP90B1 1.85841323123189 Human Diseases Cardiovascular disease hsa05410 Hypertrophic cardiomyopathy 4/152 99/9376 2.4922913343966 ITGB4/ITGB1/ITGAV/ITGB8 1.91608698573203 Metabolism Lipid metabolism hsa00590 Arachidonic acid metabolism 3/152 63/9376 2.93734335839599 PTGES/PLA2G2A/GPX4 1.98052284603238 Genetic Information Processing Folding, sorting and degradation hsa03060 Protein export 2/152 31/9376 3.97962648556876 SPCS2/SEC11C 2.13304886742959 Human Diseases Infectious disease: viral hsa05165 Human papillomavirus infection 9/152 333/9376 1.66714082503556 EGFR/ITGB4/ITGB1/ITGAV/CCND2/ATP6V0B/PRKCZ/LAMB4/ITGB8 1.59122339012128 Cellular Processes Transport and catabolism hsa04136 Autophagy - other 2/152 32/9376 3.85526315789474 GABARAPL1/ATG9B 2.07683742315243 Organismal Systems Circulatory system hsa04261 Adrenergic signaling in cardiomyocytes 5/152 154/9376 2.00273410799727 ATP2B1/ATP1A4/ATP1B3/ADCY2/ADRB1 1.61057656019884 Human Diseases Infectious disease: bacterial hsa05120 Epithelial cell signaling in Helicobacter pylori infection 3/152 71/9376 2.60637509266123 PLCG2/EGFR/ATP6V0B 1.74407731095289 Human Diseases Infectious disease: parasitic hsa05145 Toxoplasmosis 4/152 112/9376 2.20300751879699 ITGB1/HSPA1A/HLA-DRA/LAMB4 1.64409104886419 Cellular Processes Transport and catabolism hsa04148 Efferocytosis 5/152 157/9376 1.96446530338585 BSG/ITGAV/DNMT3A/CALR/C1QA 1.56438020621073 Human Diseases Cancer: specific types hsa05218 Melanoma 3/152 73/9376 2.53496755587599 EGFR/GADD45G/CDH1 1.69003969383681 Human Diseases Cancer: specific types hsa05223 Non-small cell lung cancer 3/152 73/9376 2.53496755587599 PLCG2/EGFR/GADD45G 1.69003969383681 Metabolism Glycan biosynthesis and metabolism hsa00512 Mucin type O-glycan biosynthesis 2/152 36/9376 3.42690058479532 GALNT11/C1GALT1 1.87274041784967 Environmental Information Processing Signal transduction hsa04020 Calcium signaling pathway 7/152 254/9376 1.69995855781185 PLCG2/EGFR/ATP2B1/MCOLN3/CASQ1/ADCY2/ADRB1 1.45175034211101 Human Diseases Cancer: specific types hsa05216 Thyroid cancer 2/152 37/9376 3.33428165007112 GADD45G/CDH1 1.82621420006516 Organismal Systems Digestive system hsa04971 Gastric acid secretion 3/152 76/9376 2.43490304709141 ATP1A4/ATP1B3/ADCY2 1.61226217327306 Human Diseases Cancer: specific types hsa05214 Glioma 3/152 76/9376 2.43490304709141 PLCG2/EGFR/GADD45G 1.61226217327306 Organismal Systems Excretory system hsa04960 Aldosterone-regulated sodium reabsorption 2/152 38/9376 3.24653739612188 ATP1A4/ATP1B3 1.78125583843666 Human Diseases Cancer: specific types hsa05212 Pancreatic cancer 3/152 77/9376 2.40328092959672 EGFR/GADD45G/RALBP1 1.58715611612352 Environmental Information Processing Signal transduction hsa04015 Rap1 signaling pathway 6/152 212/9376 1.74577954319762 EGFR/ITGB1/PRKCZ/VAV3/ADCY2/CDH1 1.40988484305544 Human Diseases Immune disease hsa05330 Allograft rejection 2/152 39/9376 3.16329284750337 HLA-DRA/CD86 1.73776771124845 Environmental Information Processing Signal transduction hsa04022 cGMP-PKG signaling pathway 5/152 166/9376 1.85795814838301 ATP2B1/ATP1A4/ATP1B3/ADCY2/ADRB1 1.43165415232436 Genetic Information Processing Folding, sorting and degradation hsa03018 RNA degradation 3/152 78/9376 2.37246963562753 BTG3/HSPD1/DCP2 1.56243896246031 Human Diseases Infectious disease: bacterial hsa05100 Bacterial invasion of epithelial cells 3/152 78/9376 2.37246963562753 ITGB1/WASF2/CDH1 1.56243896246031 Environmental Information Processing Signal transduction hsa04151 PI3K-Akt signaling pathway 9/152 362/9376 1.53358534457691 EGFR/ITGB4/ITGB1/ITGAV/CCND2/CSF3R/LAMB4/HSP90B1/ITGB8 1.32906795281727 Organismal Systems Endocrine system hsa04919 Thyroid hormone signaling pathway 4/152 122/9376 2.02243313201035 PLCG2/ATP1A4/ITGAV/ATP1B3 1.45914303743528 Organismal Systems Nervous system hsa04721 Synaptic vesicle cycle 3/152 79/9376 2.34243837441706 ATP6V0B/VAMP2/AP2S1 1.53809894201101 Human Diseases Cancer: specific types hsa05225 Hepatocellular carcinoma 5/152 170/9376 1.81424148606811 PLCG2/EGFR/GADD45G/GSTA3/BRD7 1.37527638770604 Human Diseases Cancer: specific types hsa05219 Bladder cancer 2/152 41/9376 3.00898587933248 EGFR/CDH1 1.65485305660238 Organismal Systems Immune system hsa04611 Platelet activation 4/152 126/9376 1.95822890559733 PLCG2/ITGB1/PRKCZ/ADCY2 1.39005331797439 Organismal Systems Digestive system hsa04975 Fat digestion and absorption 2/152 43/9376 2.86903304773562 PLA2G2A/PLPP3 1.57684265843201 Human Diseases Infectious disease: viral hsa05166 Human T-cell leukemia virus 1 infection 6/152 224/9376 1.65225563909774 CCND2/HLA-DRA/ADCY2/CALR/CANX/EGR1 1.26832814832802 Human Diseases Infectious disease: viral hsa05163 Human cytomegalovirus infection 6/152 227/9376 1.63041966148852 EGFR/ITGAV/PDIA3/AKAP13/ADCY2/CALR 1.23425145900374 Human Diseases Immune disease hsa05332 Graft-versus-host disease 2/152 45/9376 2.74152046783626 HLA-DRA/CD86 1.50320610265305 Environmental Information Processing Signal transduction hsa04068 FoxO signaling pathway 4/152 133/9376 1.85516422635536 EGFR/GADD45G/CCND2/GABARAPL1 1.27501899235631 Organismal Systems Nervous system hsa04727 GABAergic synapse 3/152 89/9376 2.07924305144885 SLC38A1/ADCY2/GABARAPL1 1.31318020276464 Metabolism Carbohydrate metabolism hsa00620 Pyruvate metabolism 2/152 47/9376 2.62486002239642 ACSS1/LDHB 1.4334914963727 Genetic Information Processing Information processing in viruses hsa03265 Virion - Ebolavirus, Lyssavirus and Morbillivirus 1/152 12/9376 5.14035087719298 CD46 1.84223425248241 Organismal Systems Digestive system hsa04976 Bile secretion 3/152 90/9376 2.05614035087719 ATP1A4/ATP1B3/ADCY2 1.29233865801964 Organismal Systems Digestive system hsa04973 Carbohydrate digestion and absorption 2/152 48/9376 2.57017543859649 ATP1A4/ATP1B3 1.39998155771406 Metabolism Glycan biosynthesis and metabolism hsa00514 Other types of O-glycan biosynthesis 2/152 49/9376 2.51772287862513 GALNT11/C1GALT1 1.36731103092107 Organismal Systems Immune system hsa04672 Intestinal immune network for IgA production 2/152 50/9376 2.46736842105263 HLA-DRA/CD86 1.33543959944662 Human Diseases Cardiovascular disease hsa05418 Fluid shear stress and atherosclerosis 4/152 142/9376 1.73758339510749 GSTA3/ITGAV/PRKCZ/HSP90B1 1.13686305468492 Human Diseases Immune disease hsa05323 Rheumatoid arthritis 3/152 95/9376 1.94792243767313 ATP6V0B/HLA-DRA/CD86 1.19202401409822 Metabolism Lipid metabolism hsa00565 Ether lipid metabolism 2/152 51/9376 2.41898864809082 PLA2G2A/PLPP3 1.30432967158424 Human Diseases Infectious disease: bacterial hsa05110 Vibrio cholerae infection 2/152 51/9376 2.41898864809082 PLCG2/ATP6V0B 1.30432967158424 Human Diseases Infectious disease: bacterial hsa05150 Staphylococcus aureus infection 3/152 99/9376 1.86921850079745 HLA-DRA/KRT23/C1QA 1.11606776689415 Human Diseases Cancer: overview hsa05231 Choline metabolism in cancer 3/152 99/9376 1.86921850079745 EGFR/PLPP3/WASF2 1.11606776689415 Cellular Processes Transport and catabolism hsa04142 Lysosome biogenesis 6/152 250/9376 1.48042105263158 MCOLN3/ATP6V0B/FUCA1/CD164/AP2S1/PSAP 0.988324559608361 Environmental Information Processing Signal transduction hsa04072 Phospholipase D signaling pathway 4/152 149/9376 1.65595196043801 PLCG2/EGFR/PLPP3/ADCY2 1.03605471929237 Metabolism Lipid metabolism hsa00600 Sphingolipid metabolism 2/152 55/9376 2.24306220095694 PLPP3/PSAP 1.18683606893202 Human Diseases Endocrine and metabolic disease hsa04933 AGE-RAGE signaling pathway in diabetic complications 3/152 101/9376 1.83220427305888 PLCG2/PRKCZ/EGR1 1.07939761512847 Human Diseases Infectious disease: bacterial hsa05131 Shigellosis 6/152 253/9376 1.462866652798 PLCG2/CD44/EGFR/ITGB1/UBB/WASF2 0.958065279172052 Human Diseases Infectious disease: bacterial hsa05134 Legionellosis 2/152 56/9376 2.20300751879699 HSPA1A/HSPD1 1.15905003400915 Human Diseases Infectious disease: parasitic hsa05142 Chagas disease 3/152 103/9376 1.79662749105774 CFLAR/CALR/C1QA 1.0435459021842 Environmental Information Processing Signal transduction hsa04064 NF-kappa B signaling pathway 3/152 105/9376 1.76240601503759 PLCG2/GADD45G/CFLAR 1.00847574653877 Cellular Processes Transport and catabolism hsa04137 Mitophagy - animal 3/152 105/9376 1.76240601503759 UBB/GABARAPL1/ATG9B 1.00847574653877 Metabolism Energy metabolism hsa00910 Nitrogen metabolism 1/152 17/9376 3.62848297213622 CA8 1.39239575311828 NA NA hsa03273 Virion - Lassa virus and SFTS virus 1/152 17/9376 3.62848297213622 NRP2 1.39239575311828 Human Diseases Endocrine and metabolic disease hsa04932 Non-alcoholic fatty liver disease 4/152 157/9376 1.57157224270868 MT-CYB/COX4I1/NDUFA10/MT-CO2 0.927100539308061 Cellular Processes Cell growth and death hsa04110 Cell cycle 4/152 158/9376 1.5616255829447 GADD45G/CDKN1C/CCND2/TFDP2 0.913913008374854 Metabolism Glycan biosynthesis and metabolism hsa00511 Other glycan degradation 1/152 18/9376 3.42690058479532 FUCA1 1.32295326809711 Environmental Information Processing Signal transduction hsa04066 HIF-1 signaling pathway 3/152 110/9376 1.6822966507177 PLCG2/EGFR/LDHB 0.923998399755118 Organismal Systems Aging hsa04213 Longevity regulating pathway - multiple species 2/152 62/9376 1.98981324278438 HSPA1A/ADCY2 1.0037574298246 Genetic Information Processing Replication and repair hsa03420 Nucleotide excision repair 2/152 63/9376 1.95822890559733 DDB1/POLR2J3 0.979585900991437 Human Diseases Cancer: overview hsa05207 Chemical carcinogenesis - receptor activation 5/152 217/9376 1.42129517341741 EGFR/GSTA3/ADCY2/ADRB1/HSP90B1 0.806009398777635 Metabolism Lipid metabolism hsa00100 Steroid biosynthesis 1/152 20/9376 3.08421052631579 FDFT1 1.19773092012126 NA NA hsa04081 Hormone signaling 5/152 219/9376 1.40831530882 ITGAV/SLC40A1/CGA/ADCY2/ADRB1 0.784854040553425 Metabolism Lipid metabolism hsa00561 Glycerolipid metabolism 2/152 65/9376 1.89797570850202 LPIN2/PLPP3 0.932547342011096 Organismal Systems Endocrine system hsa04929 GnRH secretion 2/152 65/9376 1.89797570850202 KCNN4/CGA 0.932547342011096 Environmental Information Processing Signal transduction hsa04630 JAK-STAT signaling pathway 4/152 168/9376 1.46867167919799 EGFR/CCND2/CSF3R/IL6ST 0.786843717239302 Organismal Systems Immune system hsa04670 Leukocyte transendothelial migration 3/152 116/9376 1.59528130671506 PLCG2/ITGB1/VAV3 0.82812049140152 Cellular Processes Transport and catabolism hsa04140 Autophagy - animal 4/152 169/9376 1.45998131423233 CFLAR/UBB/GABARAPL1/ATG9B 0.774590659177354 Metabolism Carbohydrate metabolism hsa00010 Glycolysis / Gluconeogenesis 2/152 67/9376 1.84131971720346 ACSS1/LDHB 0.887145263969575 Organismal Systems Immune system hsa04664 Fc epsilon RI signaling pathway 2/152 69/9376 1.78794813119756 PLCG2/VAV3 0.843266996271434 Organismal Systems Endocrine system hsa04614 Renin-angiotensin system 1/152 23/9376 2.68192219679634 MME 1.03667383649532 Human Diseases Cardiovascular disease hsa05416 Viral myocarditis 2/152 70/9376 1.76240601503759 HLA-DRA/CD86 0.821867098730391 Organismal Systems Endocrine system hsa04917 Prolactin signaling pathway 2/152 71/9376 1.73758339510749 CCND2/CGA 0.800810763450914 Human Diseases Cancer: overview hsa05230 Central carbon metabolism in cancer 2/152 71/9376 1.73758339510749 EGFR/LDHB 0.800810763450914 Environmental Information Processing Signal transduction hsa04014 Ras signaling pathway 5/152 238/9376 1.29588677576294 PLCG2/EGFR/RASA1/PLA2G2A/RALBP1 0.593521208166536 Cellular Processes Cell growth and death hsa04115 p53 signaling pathway 2/152 75/9376 1.64491228070175 GADD45G/CCND2 0.719803976549727 Metabolism Lipid metabolism hsa00592 alpha-Linolenic acid metabolism 1/152 26/9376 2.37246963562753 PLA2G2A 0.899562615547994 Organismal Systems Endocrine system hsa04926 Relaxin signaling pathway 3/152 130/9376 1.42348178137652 EGFR/PRKCZ/ADCY2 0.624133146748001 Metabolism Carbohydrate metabolism hsa00650 Butanoate metabolism 1/152 27/9376 2.28460038986355 HADHA 0.858055020456713 Human Diseases Infectious disease: bacterial hsa05133 Pertussis 2/152 78/9376 1.58164642375169 ITGB1/C1QA 0.662154565211794 Human Diseases Infectious disease: parasitic hsa05140 Leishmaniasis 2/152 78/9376 1.58164642375169 ITGB1/HLA-DRA 0.662154565211794 Metabolism Lipid metabolism hsa00062 Fatty acid elongation 1/152 28/9376 2.20300751879699 HADHA 0.818343788884997 Human Diseases Drug resistance: antineoplastic hsa01521 EGFR tyrosine kinase inhibitor resistance 2/152 80/9376 1.54210526315789 PLCG2/EGFR 0.6250695526035 Environmental Information Processing Signal transduction hsa04392 Hippo signaling pathway - multiple species 1/152 29/9376 2.12704174228675 FRMD6 0.780280338958318 Human Diseases Infectious disease: viral hsa05162 Measles 3/152 136/9376 1.36068111455108 CD46/CCND2/HSPA1A 0.54388196335373 Cellular Processes Transport and catabolism hsa04144 Endocytosis 5/152 250/9376 1.23368421052632 EGFR/HSPA1A/PRKCZ/AP2S1/SNX6 0.480736310764803 Organismal Systems Immune system hsa04062 Chemokine signaling pathway 4/152 193/9376 1.27842923370603 PLCG2/PRKCZ/VAV3/ADCY2 0.501705635677395 Metabolism Lipid metabolism hsa00591 Linoleic acid metabolism 1/152 30/9376 2.05614035087719 PLA2G2A 0.743733184501956 Human Diseases Infectious disease: bacterial hsa05135 Yersinia infection 3/152 138/9376 1.34096109839817 ITGB1/VAV3/WASF2 0.517968299123417 Genetic Information Processing Chromosome hsa03083 Polycomb repressive complex 2/152 83/9376 1.4863665187064 CBX4/YY1 0.571310930583833 Human Diseases Infectious disease: viral hsa05167 Kaposi sarcoma-associated herpesvirus infection 4/152 196/9376 1.25886143931257 PLCG2/UBB/IL6ST/CD86 0.470134196243249 Environmental Information Processing Signal transduction hsa04371 Apelin signaling pathway 3/152 140/9376 1.3218045112782 ADCY2/EGR1/CDH1 0.492449803841386 Metabolism Metabolism of other amino acids hsa00410 beta-Alanine metabolism 1/152 31/9376 1.98981324278438 HADHA 0.70858546422305 Metabolism Carbohydrate metabolism hsa00630 Glyoxylate and dicarboxylate metabolism 1/152 31/9376 1.98981324278438 ACSS1 0.70858546422305 Genetic Information Processing Folding, sorting and degradation hsa04120 Ubiquitin mediated proteolysis 3/152 142/9376 1.30318754633062 UBB/DDB1/UBE2A 0.467313557151892 Human Diseases Immune disease hsa05310 Asthma 1/152 32/9376 1.92763157894737 HLA-DRA 0.674732895540305 Environmental Information Processing Signal transduction hsa04012 ErbB signaling pathway 2/152 86/9376 1.43451652386781 PLCG2/EGFR 0.519631476186778 Human Diseases Immune disease hsa05322 Systemic lupus erythematosus 3/152 143/9376 1.29407434670593 HLA-DRA/C1QA/CD86 0.454884906603689 Human Diseases Cancer: specific types hsa05210 Colorectal cancer 2/152 87/9376 1.41802782819117 EGFR/GADD45G 0.502838038617915 Genetic Information Processing Folding, sorting and degradation hsa04130 SNARE interactions in vesicular transport 1/152 33/9376 1.86921850079745 VAMP2 0.642082069233659 Human Diseases Cancer: overview hsa05206 MicroRNAs in cancer 6/152 323/9376 1.14583672804302 PLCG2/CD44/EGFR/CCND2/PDCD4/DNMT3A 0.342388916808452 Genetic Information Processing Transcription hsa03020 RNA polymerase 1/152 34/9376 1.81424148606811 POLR2J3 0.610549019642645 Organismal Systems Immune system hsa04662 B cell receptor signaling pathway 2/152 91/9376 1.3556969346443 PLCG2/VAV3 0.437680955273888 Human Diseases Cancer: specific types hsa05226 Gastric cancer 3/152 150/9376 1.23368421052632 EGFR/GADD45G/CDH1 0.370353163416467 Metabolism Carbohydrate metabolism hsa00500 Starch and sucrose metabolism 1/152 36/9376 1.71345029239766 AGL 0.550540556572674 Organismal Systems Immune system hsa04657 IL-17 signaling pathway 2/152 94/9376 1.31243001119821 HSP90B1/JUND 0.39079020896506 Human Diseases Infectious disease: viral hsa05170 Human immunodeficiency virus 1 infection 4/152 214/9376 1.15297589768815 PLCG2/PDIA3/DDB1/CALR 0.290591253522762 Metabolism Metabolism of cofactors and vitamins hsa00760 Nicotinate and nicotinamide metabolism 1/152 38/9376 1.62326869806094 PNP 0.494183185756164 Human Diseases Cardiovascular disease hsa05417 Lipid and atherosclerosis 4/152 216/9376 1.14230019493177 HSPA1A/VAV3/HSPD1/HSP90B1 0.271601659250536 Human Diseases Drug resistance: antineoplastic hsa01522 Endocrine resistance 2/152 99/9376 1.2461456671983 EGFR/ADCY2 0.316048548056263 Organismal Systems Sensory system hsa04750 Inflammatory mediator regulation of TRP channels 2/152 99/9376 1.2461456671983 PLCG2/ADCY2 0.316048548056263 Metabolism Amino acid metabolism hsa00380 Tryptophan metabolism 1/152 42/9376 1.46867167919799 HADHA 0.390757428384437 Metabolism Lipid metabolism hsa00071 Fatty acid degradation 1/152 43/9376 1.43451652386781 HADHA 0.366587520460618 Metabolism Glycan biosynthesis and metabolism hsa00513 Various types of N-glycan biosynthesis 1/152 44/9376 1.40191387559809 TUSC3 0.343020249242941 Organismal Systems Excretory system hsa04962 Vasopressin-regulated water reabsorption 1/152 44/9376 1.40191387559809 VAMP2 0.343020249242941 Human Diseases Cancer: specific types hsa05215 Prostate cancer 2/152 106/9376 1.16385302879841 EGFR/HSP90B1 0.217778661504347 Organismal Systems Endocrine system hsa04922 Glucagon signaling pathway 2/152 107/9376 1.15297589768815 ADCY2/LDHB 0.204289592992314 Cellular Processes Cellular community - eukaryotes hsa04530 Tight junction 3/152 170/9376 1.08854489164087 AMOT/ITGB1/PRKCZ 0.1495547706783 Organismal Systems Immune system hsa04659 Th17 cell differentiation 2/152 109/9376 1.13182037662965 HLA-DRA/IL6ST 0.177694506098511 Human Diseases Endocrine and metabolic disease hsa04930 Type II diabetes mellitus 1/152 47/9376 1.31243001119821 PRKCZ 0.275633444168148 Environmental Information Processing Signal transduction hsa04010 MAPK signaling pathway 5/152 300/9376 1.0280701754386 EGFR/GADD45G/HSPA1A/RASA1/JUND 0.063431691953989 Human Diseases Infectious disease: viral hsa05171 Coronavirus disease - COVID-19 4/152 238/9376 1.03670942061035 PLCG2/EGFR/IL6ST/C1QA 0.0736356655871787 Metabolism Amino acid metabolism hsa00280 Valine, leucine and isoleucine degradation 1/152 48/9376 1.28508771929825 HADHA 0.254186595674341 NA NA hsa03272 Virion - Hepatitis viruses 1/152 48/9376 1.28508771929825 EGFR 0.254186595674341 Environmental Information Processing Signal transduction hsa04310 Wnt signaling pathway 3/152 178/9376 1.03962152572442 SERPINF1/CCND2/LGR5 0.0685081561071997 Human Diseases Infectious disease: viral hsa05168 Herpes simplex virus 1 infection 3/152 180/9376 1.0280701754386 PDIA3/HLA-DRA/CALR 0.0488123462489203 Organismal Systems Nervous system hsa04724 Glutamatergic synapse 2/152 116/9376 1.06352087114338 SLC38A1/ADCY2 0.088366515850772 Human Diseases Infectious disease: bacterial hsa05152 Tuberculosis 3/152 181/9376 1.02239022971794 ATP6V0B/HLA-DRA/HSPD1 0.0390453890959298 Genetic Information Processing Chromosome hsa03082 ATP-dependent chromatin remodeling 2/152 117/9376 1.05443094916779 YY1/BRD7 0.0760509391436159 Organismal Systems Digestive system hsa04979 Cholesterol metabolism 1/152 52/9376 1.18623481781377 LRPAP1 0.17286584874784 Organismal Systems Endocrine system hsa04935 Growth hormone synthesis, secretion and action 2/152 122/9376 1.01121656600518 PLCG2/ADCY2 0.0160074763600495 Metabolism Glycan biosynthesis and metabolism hsa00510 N-Glycan biosynthesis 1/152 56/9376 1.1015037593985 TUSC3 0.0977948466195218 Environmental Information Processing Signal transduction hsa04340 Hedgehog signaling pathway 1/152 56/9376 1.1015037593985 CCND2 0.0977948466195218 Environmental Information Processing Signal transduction hsa04071 Sphingolipid signaling pathway 2/152 125/9376 0.986947368421053 ORMDL1/PRKCZ -0.0188584732868347 Metabolism Global and overview maps hsa01212 Fatty acid metabolism 1/152 57/9376 1.08217913204063 HADHA 0.0798844238016541 Metabolism Nucleotide metabolism hsa00230 Purine metabolism 2/152 128/9376 0.963815789473684 ADCY2/PNP -0.0529112425969447 Environmental Information Processing Signal transduction hsa04370 VEGF signaling pathway 1/152 60/9376 1.0280701754386 PLCG2 0.027999727020792 Human Diseases Infectious disease: bacterial hsa05130 Pathogenic Escherichia coli infection 3/152 200/9376 0.925263157894737 ITGB1/WASF2/TUBB4B -0.137142108997658 Human Diseases Cancer: overview hsa05202 Transcriptional misregulation in cancer 3/152 201/9376 0.920659858601728 GADD45G/CCND2/CD86 -0.145960636114609 Organismal Systems Immune system hsa04650 Natural killer cell mediated cytotoxicity 2/152 133/9376 0.927582113177681 PLCG2/VAV3 -0.107972455160206 Organismal Systems Circulatory system hsa04270 Vascular smooth muscle contraction 2/152 134/9376 0.920659858601728 PLA2G2A/ADCY2 -0.118743589273749 Metabolism Amino acid metabolism hsa00310 Lysine degradation 1/152 63/9376 0.979114452798663 HADHA -0.0213510440495082 Human Diseases Cancer: specific types hsa05217 Basal cell carcinoma 1/152 63/9376 0.979114452798663 GADD45G -0.0213510440495082 Human Diseases Cancer: overview hsa05203 Viral carcinogenesis 3/152 205/9376 0.902695763799743 CCND2/IL6ST/DDB1 -0.180820687769747 Cellular Processes Cell growth and death hsa04210 Apoptosis 2/152 137/9376 0.900499423741836 GADD45G/CFLAR -0.150598685458698 Organismal Systems Endocrine system hsa04927 Cortisol synthesis and secretion 1/152 65/9376 0.948987854251012 ADCY2 -0.0529760888608649 Organismal Systems Endocrine system hsa04910 Insulin signaling pathway 2/152 138/9376 0.89397406559878 PRKCZ/SORBS1 -0.161068442009295 Metabolism Lipid metabolism hsa00140 Steroid hormone biosynthesis 1/152 66/9376 0.934609250398724 HSD17B1 -0.0684323143988606 Human Diseases Immune disease hsa05321 Inflammatory bowel disease 1/152 66/9376 0.934609250398724 HLA-DRA -0.0684323143988606 Metabolism Metabolism of cofactors and vitamins hsa00830 Retinol metabolism 1/152 68/9376 0.907120743034056 DHRS3 -0.0986717399421421 Organismal Systems Development and regeneration hsa04380 Osteoclast differentiation 2/152 142/9376 0.868791697553744 PLCG2/JUND -0.202235940381137 Organismal Systems Endocrine system hsa04924 Renin secretion 1/152 69/9376 0.89397406559878 ADRB1 -0.113469615180764 Cellular Processes Cellular community - eukaryotes hsa04550 Signaling pathways regulating pluripotency of stem cells 2/152 144/9376 0.85672514619883 IL6ST/ISL1 -0.22240835971403 Human Diseases Endocrine and metabolic disease hsa04936 Alcoholic liver disease 2/152 144/9376 0.85672514619883 LPIN2/C1QA -0.22240835971403 Human Diseases Cancer: overview hsa05204 Chemical carcinogenesis - DNA adducts 1/152 70/9376 0.881203007518797 GSTA3 -0.128062131754834 Human Diseases Cancer: specific types hsa05224 Breast cancer 2/152 148/9376 0.833570412517781 EGFR/GADD45G -0.261972308145113 Metabolism Xenobiotics biodegradation and metabolism hsa00982 Drug metabolism - cytochrome P450 1/152 73/9376 0.844989185291997 GSTA3 -0.170670988339556 Human Diseases Drug resistance: antineoplastic hsa01524 Platinum drug resistance 1/152 75/9376 0.822456140350877 GSTA3 -0.198161486471252 Organismal Systems Endocrine system hsa03320 PPAR signaling pathway 1/152 76/9376 0.811634349030471 SORBS1 -0.211648316182564 Organismal Systems Endocrine system hsa04921 Oxytocin signaling pathway 2/152 154/9376 0.801093643198906 EGFR/ADCY2 -0.319480421961732 Human Diseases Cancer: specific types hsa05220 Chronic myeloid leukemia 1/152 77/9376 0.801093643198906 GADD45G -0.224969522548439 Human Diseases Endocrine and metabolic disease hsa04934 Cushing syndrome 2/152 155/9376 0.795925297113752 EGFR/ADCY2 -0.328862077482147 Metabolism Carbohydrate metabolism hsa00562 Inositol phosphate metabolism 1/152 78/9376 0.790823211875843 PLCG2 -0.238129832036724 Human Diseases Infectious disease: viral hsa05160 Hepatitis C 2/152 156/9376 0.790823211875843 EGFR/CFLAR -0.338187938095063 Metabolism Xenobiotics biodegradation and metabolism hsa00980 Metabolism of xenobiotics by cytochrome P450 1/152 79/9376 0.780812791472352 GSTA3 -0.251133772665817 Cellular Processes Cell growth and death hsa04218 Cellular senescence 2/152 157/9376 0.785786121354341 GADD45G/CCND2 -0.347458794497273 Environmental Information Processing Signal transduction hsa04150 mTOR signaling pathway 2/152 158/9376 0.780812791472352 LPIN2/SLC3A2 -0.356675420824824 Metabolism Xenobiotics biodegradation and metabolism hsa00983 Drug metabolism - other enzymes 1/152 82/9376 0.752246469833119 GSTA3 -0.289249907330143 Cellular Processes Transport and catabolism hsa04146 Peroxisome 1/152 83/9376 0.743183259353202 CROT -0.301670048091855 Metabolism Global and overview maps hsa01232 Nucleotide metabolism 1/152 85/9376 0.725696594427245 PNP -0.326104819587435 Organismal Systems Aging hsa04211 Longevity regulating pathway 1/152 90/9376 0.685380116959064 ADCY2 -0.384982390927224 Human Diseases Cancer: overview hsa05235 PD-L1 expression and PD-1 checkpoint pathway in cancer 1/152 90/9376 0.685380116959064 EGFR -0.384982390927224 Human Diseases Infectious disease: viral hsa05164 Influenza A 2/152 173/9376 0.713112260419836 HLA-DRA/PABPN1 -0.488897835186996 Human Diseases Substance dependence hsa05032 Morphine addiction 1/152 91/9376 0.677848467322152 ADCY2 -0.396403726971635 Organismal Systems Immune system hsa04658 Th1 and Th2 cell differentiation 1/152 93/9376 0.663271080928127 HLA-DRA -0.418914603527336 Organismal Systems Environmental adaptation hsa04713 Circadian entrainment 1/152 97/9376 0.635919696147585 ADCY2 -0.462679491653714 Environmental Information Processing Signal transduction hsa04070 Phosphatidylinositol signaling system 1/152 98/9376 0.629430719656283 PLCG2 -0.473372530911745 Environmental Information Processing Signaling molecules and interaction hsa04061 Viral protein interaction with cytokine and cytokine receptor 1/152 100/9376 0.616842105263158 IL6ST -0.494475972648684 Organismal Systems Endocrine system hsa04916 Melanogenesis 1/152 101/9376 0.610734757686295 ADCY2 -0.504890431121459 Organismal Systems Immune system hsa04621 NOD-like receptor signaling pathway 2/152 187/9376 0.65972417675204 TXNIP/GABARAPL1 -0.603344774770974 Genetic Information Processing Translation hsa03015 mRNA surveillance pathway 1/152 103/9376 0.59887583035258 PABPN1 -0.525454479290952 Human Diseases Infectious disease: parasitic hsa05146 Amoebiasis 1/152 103/9376 0.59887583035258 LAMB4 -0.525454479290952 Organismal Systems Immune system hsa04625 C-type lectin receptor signaling pathway 1/152 105/9376 0.587468671679198 PLCG2 -0.545677540697837 Genetic Information Processing Translation hsa03013 Nucleocytoplasmic transport 1/152 108/9376 0.571150097465887 RANBP17 -0.575402793401307 Organismal Systems Immune system hsa04620 Toll-like receptor signaling pathway 1/152 109/9376 0.565910188314824 CD86 -0.585155168434292 Human Diseases Endocrine and metabolic disease hsa04931 Insulin resistance 1/152 109/9376 0.565910188314824 PRKCZ -0.585155168434292 Environmental Information Processing Signal transduction hsa04350 TGF-beta signaling pathway 1/152 110/9376 0.560765550239234 FBN1 -0.594832069407573 Organismal Systems Endocrine system hsa04914 Progesterone-mediated oocyte maturation 1/152 110/9376 0.560765550239234 ADCY2 -0.594832069407573 NA NA hsa04082 Neuroactive ligand signaling 2/152 199/9376 0.619941814334832 ADCY2/ADRB1 -0.695623184394099 Organismal Systems Nervous system hsa04725 Cholinergic synapse 1/152 115/9376 0.536384439359268 ADCY2 -0.642134149947157 Organismal Systems Nervous system hsa04726 Serotonergic synapse 1/152 115/9376 0.536384439359268 APP -0.642134149947157 Metabolism Global and overview maps hsa01200 Carbon metabolism 1/152 116/9376 0.531760435571688 ACSS1 -0.651387459699976 Environmental Information Processing Signal transduction hsa04668 TNF signaling pathway 1/152 119/9376 0.518354710305175 CFLAR -0.678755639946647 Organismal Systems Nervous system hsa04722 Neurotrophin signaling pathway 1/152 120/9376 0.514035087719298 PLCG2 -0.687751661852538 Organismal Systems Immune system hsa04660 T cell receptor signaling pathway 1/152 122/9376 0.505608283002589 VAV3 -0.705560304177566 Environmental Information Processing Signaling molecules and interaction hsa04060 Cytokine-cytokine receptor interaction 3/152 298/9376 0.620981985164253 CSF3R/IL1RL1/IL6ST -0.853533714666045 NA NA hsa04382 Cornified envelope formation 2/152 217/9376 0.568518069366966 ITGB4/KRT23 -0.825498399784348 Cellular Processes Cell growth and death hsa04114 Oocyte meiosis 1/152 138/9376 0.44698703279939 ADCY2 -0.840105183142007 NA NA hsa04519 Cadherin signaling 4/152 404/9376 0.610734757686295 EGFR/VAV3/KRT23/CDH1 -1.02669030782409 Genetic Information Processing Transcription hsa03040 Spliceosome 2/152 243/9376 0.507688975525233 HSPA1A/SF1 -0.998122289645993 Human Diseases Infectious disease: bacterial hsa05132 Salmonella infection 2/152 248/9376 0.497453310696095 HSP90B1/TUBB4B -1.02958504573717 Metabolism Global and overview maps hsa01240 Biosynthesis of cofactors 1/152 154/9376 0.400546821599453 DHRS3 -0.962832749348588 Human Diseases Infectious disease: viral hsa05161 Hepatitis B 1/152 163/9376 0.37843073942525 DDB1 -1.027615343428 Cellular Processes Cell growth and death hsa04217 Necroptosis 1/152 168/9376 0.367167919799499 CFLAR -1.06244940429371 Environmental Information Processing Signaling molecules and interaction hsa04080 Neuroactive ligand-receptor interaction 3/152 370/9376 0.500142247510669 CGA/ADRB1/PGRMC2 -1.2592997231669 Cellular Processes Cell motility hsa04814 Motor proteins 1/152 194/9376 0.317959848073793 TUBB4B -1.23222480852315 Organismal Systems Immune system hsa04613 Neutrophil extracellular trap formation 1/152 195/9376 0.316329284750337 PLCG2 -1.23841748323068