ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0022853	active monoatomic ion transmembrane transporter activity	12/258	118/18639	0.101694915254237	7.34686637761135	8.91960741501218e-08	4.15337525578853e-05
GO:0001618	virus receptor activity	10/258	81/18639	0.123456790123457	8.91903531438415	1.71957260029215e-07	4.15337525578853e-05
GO:0140272	exogenous protein binding	10/258	82/18639	0.121951219512195	8.810266591038	1.93480213778969e-07	4.15337525578853e-05
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	9/258	68/18639	0.132352941176471	9.56173050615595	3.92312701132886e-07	6.31623448823947e-05
GO:0015399	primary active transmembrane transporter activity	13/258	166/18639	0.0783132530120482	5.65767722050995	5.57493977616477e-07	7.18052243170022e-05
GO:0009055	electron transfer activity	10/258	116/18639	0.0862068965517241	6.22794707297514	4.88782365377053e-06	0.000524626405504703
GO:0051082	unfolded protein binding	10/258	121/18639	0.0826446280991736	5.97059388814146	7.13660834145136e-06	0.000656567967413525
GO:0015078	proton transmembrane transporter activity	12/258	185/18639	0.0648648648648649	4.68610936517913	1.07535357097151e-05	0.000865659624632068
GO:0008137	NADH dehydrogenase (ubiquinone) activity	6/258	41/18639	0.146341463414634	10.5723199092456	1.98768192179919e-05	0.00142229684182076
GO:0003954	NADH dehydrogenase activity	6/258	44/18639	0.136363636363636	9.8514799154334	3.01406229238278e-05	0.00194105611629451
GO:0022804	active transmembrane transporter activity	18/258	457/18639	0.0393873085339169	2.84550404559564	7.23666210908248e-05	0.00423673672568102
GO:0005178	integrin binding	10/258	161/18639	0.062111801242236	4.48721652462805	8.4393046002476e-05	0.00452909346879955
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	6/258	58/18639	0.103448275862069	7.47353648757017	0.000147018094181785	0.00728305020408227
GO:0033218	amide binding	11/258	247/18639	0.0445344129554656	3.21735241502683	0.000684016672681602	0.0314647669433537
GO:0016651	oxidoreductase activity, acting on NAD(P)H	6/258	88/18639	0.0681818181818182	4.9257399577167	0.00139451372392484	0.059871122547173
GO:1901681	sulfur compound binding	11/258	275/18639	0.04	2.88976744186047	0.00162821937552194	0.0655358298647583
GO:0004867	serine-type endopeptidase inhibitor activity	6/258	95/18639	0.0631578947368421	4.56279069767442	0.00206434825385623	0.078202369146083
GO:0003714	transcription corepressor activity	9/258	204/18639	0.0441176470588235	3.18724350205198	0.00220732741506367	0.0789732697389447
GO:0008201	heparin binding	8/258	172/18639	0.0465116279069767	3.36019469983775	0.00277650079718927	0.0926443119473983
GO:0140030	modification-dependent protein binding	8/258	173/18639	0.046242774566474	3.34077160908724	0.00287715254495026	0.0926443119473983
GO:0005518	collagen binding	5/258	72/18639	0.0694444444444444	5.01695736434108	0.00321618933649407	0.0986298063191516
GO:0044183	protein folding chaperone	5/258	75/18639	0.0666666666666667	4.81627906976744	0.00383698513333654	0.11231901935767
GO:0061135	endopeptidase regulator activity	8/258	184/18639	0.0434782608695652	3.14105156723964	0.00418264530349737	0.117114068497926
GO:0005537	D-mannose binding	3/258	25/18639	0.12	8.66930232558139	0.00481338733138463	0.129159226725488
GO:0050750	low-density lipoprotein particle receptor binding	3/258	26/18639	0.115384615384615	8.33586762075134	0.00538619949689632	0.138748499040049
GO:0030246	carbohydrate binding	10/258	280/18639	0.0357142857142857	2.58014950166113	0.00580708451356246	0.143837016412855
GO:0005539	glycosaminoglycan binding	9/258	242/18639	0.0371900826446281	2.68676724966366	0.00674066027332122	0.160209706430205
GO:0045296	cadherin binding	11/258	334/18639	0.0329341317365269	2.37929954045398	0.00705752041399427	0.160209706430205
GO:0004866	endopeptidase inhibitor activity	7/258	161/18639	0.0434782608695652	3.14105156723964	0.00721441224608067	0.160209706430205
GO:0015658	branched-chain amino acid transmembrane transporter activity	2/258	10/18639	0.2	14.4488372093023	0.00798190586902552	0.16675459802677
GO:0070325	lipoprotein particle receptor binding	3/258	31/18639	0.0967741935483871	6.9913728432108	0.00885147965442256	0.16675459802677
GO:0005201	extracellular matrix structural constituent	7/258	168/18639	0.0416666666666667	3.01017441860465	0.00901538757006124	0.16675459802677
GO:0030414	peptidase inhibitor activity	7/258	169/18639	0.0414201183431953	2.99236273565433	0.0092973071582702	0.16675459802677
GO:0004714	transmembrane receptor protein tyrosine kinase activity	4/258	60/18639	0.0666666666666667	4.81627906976744	0.0095376870809931	0.16675459802677
GO:0008271	secondary active sulfate transmembrane transporter activity	2/258	11/18639	0.181818181818182	13.1353065539112	0.00966712893515752	0.16675459802677
GO:0015173	aromatic amino acid transmembrane transporter activity	2/258	11/18639	0.181818181818182	13.1353065539112	0.00966712893515752	0.16675459802677
GO:0097493	structural molecule activity conferring elasticity	2/258	11/18639	0.181818181818182	13.1353065539112	0.00966712893515752	0.16675459802677
GO:0015026	coreceptor activity	4/258	61/18639	0.0655737704918033	4.73732367518109	0.010098492737646	0.16675459802677
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	4/258	61/18639	0.0655737704918033	4.73732367518109	0.010098492737646	0.16675459802677
GO:1901682	sulfur compound transmembrane transporter activity	4/258	63/18639	0.0634920634920635	4.58693244739756	0.0112832123408472	0.175442938266172
GO:0005049	nuclear export signal receptor activity	2/258	12/18639	0.166666666666667	12.0406976744186	0.0114953987434072	0.175442938266172
GO:0002020	protease binding	6/258	136/18639	0.0441176470588235	3.18724350205198	0.011714357679263	0.175442938266172
GO:0019838	growth factor binding	6/258	136/18639	0.0441176470588235	3.18724350205198	0.011714357679263	0.175442938266172
GO:0017154	semaphorin receptor activity	2/258	13/18639	0.153846153846154	11.1144901610018	0.0134624638335171	0.187214202913233
GO:0031994	insulin-like growth factor I binding	2/258	13/18639	0.153846153846154	11.1144901610018	0.0134624638335171	0.187214202913233
GO:0004857	enzyme inhibitor activity	12/258	416/18639	0.0288461538461538	2.08396690518784	0.0134866642746541	0.187214202913233
GO:0061134	peptidase regulator activity	8/258	226/18639	0.0353982300884956	2.5573163202305	0.0136631483492577	0.187214202913233
GO:0044389	ubiquitin-like protein ligase binding	10/258	322/18639	0.031055900621118	2.24360826231403	0.0145846226065114	0.195677019970695
GO:0019955	cytokine binding	6/258	144/18639	0.0416666666666667	3.01017441860465	0.0151771166132079	0.196535695733044
GO:0008195	phosphatidate phosphatase activity	2/258	14/18639	0.142857142857143	10.3205980066445	0.0155641622397287	0.196535695733044
GO:0071933	Arp2/3 complex binding	2/258	14/18639	0.142857142857143	10.3205980066445	0.0155641622397287	0.196535695733044
GO:0140662	ATP-dependent protein folding chaperone	3/258	40/18639	0.075	5.41831395348837	0.0177664139812751	0.208379897804794
GO:0004129	cytochrome-c oxidase activity	2/258	15/18639	0.133333333333333	9.63255813953488	0.0177964198435771	0.208379897804794
GO:0015116	sulfate transmembrane transporter activity	2/258	15/18639	0.133333333333333	9.63255813953488	0.0177964198435771	0.208379897804794
GO:0033130	acetylcholine receptor binding	2/258	15/18639	0.133333333333333	9.63255813953488	0.0177964198435771	0.208379897804794
GO:0015175	neutral L-amino acid transmembrane transporter activity	3/258	41/18639	0.0731707317073171	5.2861599546228	0.018977252853893	0.212786560625081
GO:0035064	methylated histone binding	4/258	74/18639	0.0540540540540541	3.90509113764928	0.0193871717546396	0.212786560625081
GO:0048029	monosaccharide binding	4/258	74/18639	0.0540540540540541	3.90509113764928	0.0193871717546396	0.212786560625081
GO:0000062	fatty-acyl-CoA binding	2/258	16/18639	0.125	9.03052325581395	0.0201552487548602	0.212786560625081
GO:0016675	oxidoreductase activity, acting on a heme group of donors	2/258	16/18639	0.125	9.03052325581395	0.0201552487548602	0.212786560625081
GO:0022858	alanine transmembrane transporter activity	2/258	16/18639	0.125	9.03052325581395	0.0201552487548602	0.212786560625081
GO:0003712	transcription coregulator activity	13/258	495/18639	0.0262626262626263	1.89732205778717	0.0208819292364519	0.212955928679103
GO:0098631	cell adhesion mediator activity	4/258	76/18639	0.0526315789473684	3.80232558139535	0.0211633221047556	0.212955928679103
GO:0140034	methylation-dependent protein binding	4/258	76/18639	0.0526315789473684	3.80232558139535	0.0211633221047556	0.212955928679103
GO:1901567	fatty acid derivative binding	2/258	17/18639	0.117647058823529	8.49931600547196	0.0226367457203208	0.224277911444409
GO:0019199	transmembrane receptor protein kinase activity	4/258	78/18639	0.0512820512820513	3.70483005366726	0.0230361339495002	0.224776822173911
GO:0031625	ubiquitin protein ligase binding	9/258	302/18639	0.0298013245033113	2.15297243184968	0.0252199738826419	0.235546178556177
GO:0034185	apolipoprotein binding	2/258	18/18639	0.111111111111111	8.02713178294574	0.0252370905595904	0.235546178556177
GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	2/258	18/18639	0.111111111111111	8.02713178294574	0.0252370905595904	0.235546178556177
GO:0005520	insulin-like growth factor binding	2/258	19/18639	0.105263157894737	7.6046511627907	0.0279525446279488	0.24496299707853
GO:0030506	ankyrin binding	2/258	19/18639	0.105263157894737	7.6046511627907	0.0279525446279488	0.24496299707853
GO:0042577	lipid phosphatase activity	2/258	19/18639	0.105263157894737	7.6046511627907	0.0279525446279488	0.24496299707853
GO:0120227	acyl-CoA binding	2/258	19/18639	0.105263157894737	7.6046511627907	0.0279525446279488	0.24496299707853
GO:0001540	amyloid-beta binding	4/258	83/18639	0.0481927710843374	3.48164752031381	0.0281479220245515	0.24496299707853
GO:0051117	ATPase binding	4/258	84/18639	0.0476190476190476	3.44019933554817	0.0292448206939452	0.251115527025343
GO:0060590	ATPase regulator activity	3/258	49/18639	0.0612244897959184	4.42311343141908	0.0302721095529103	0.256516296737819
GO:0005006	epidermal growth factor receptor activity	3/258	50/18639	0.06	4.3346511627907	0.0318843302346044	0.266668943780328
GO:0005021	vascular endothelial growth factor receptor activity	3/258	51/18639	0.0588235294117647	4.24965800273598	0.0335406891687736	0.27483494412368
GO:0001846	opsonin binding	2/258	21/18639	0.0952380952380952	6.88039867109635	0.0337142245120663	0.27483494412368
GO:0008514	organic anion transmembrane transporter activity	8/258	269/18639	0.0297397769516729	2.14852597907841	0.0341548477769272	0.274946524604264
GO:0140517	protein-RNA adaptor activity	2/258	22/18639	0.0909090909090909	6.5676532769556	0.0367533672481738	0.290468125827938
GO:0051018	protein kinase A binding	3/258	53/18639	0.0566037735849057	4.08929354980255	0.0369850719221908	0.290468125827938
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	3/258	54/18639	0.0555555555555556	4.01356589147287	0.0387726673381859	0.29873699887543
GO:0004602	glutathione peroxidase activity	2/258	23/18639	0.0869565217391304	6.28210313447927	0.0398934501603835	0.29873699887543
GO:0005158	insulin receptor binding	2/258	23/18639	0.0869565217391304	6.28210313447927	0.0398934501603835	0.29873699887543
GO:0017134	fibroblast growth factor binding	2/258	23/18639	0.0869565217391304	6.28210313447927	0.0398934501603835	0.29873699887543
GO:0042562	hormone binding	4/258	94/18639	0.0425531914893617	3.07422068283028	0.0416008474835246	0.307941905510228
GO:0004896	cytokine receptor activity	4/258	96/18639	0.0416666666666667	3.01017441860465	0.0443763651029623	0.324754308253496
GO:0001848	complement binding	2/258	25/18639	0.08	5.77953488372093	0.0464630968971446	0.328815762656716
GO:0015662	P-type ion transporter activity	2/258	25/18639	0.08	5.77953488372093	0.0464630968971446	0.328815762656716
GO:0140358	P-type transmembrane transporter activity	2/258	25/18639	0.08	5.77953488372093	0.0464630968971446	0.328815762656716
GO:0042626	ATPase-coupled transmembrane transporter activity	4/258	98/18639	0.0408163265306122	2.94874228761272	0.0472533707355013	0.330773595148509
GO:0015459	potassium channel regulator activity	3/258	59/18639	0.0508474576271186	3.67343318880568	0.0483543454347447	0.331203036724135
GO:0070063	RNA polymerase binding	3/258	59/18639	0.0508474576271186	3.67343318880568	0.0483543454347447	0.331203036724135
GO:0005112	Notch binding	2/258	26/18639	0.0769230769230769	5.55724508050089	0.0498861716804987	0.331203036724135
GO:0030247	polysaccharide binding	2/258	26/18639	0.0769230769230769	5.55724508050089	0.0498861716804987	0.331203036724135
GO:0034237	protein kinase A regulatory subunit binding	2/258	26/18639	0.0769230769230769	5.55724508050089	0.0498861716804987	0.331203036724135
GO:0016836	hydro-lyase activity	3/258	61/18639	0.0491803278688525	3.55299275638582	0.0524817499386589	0.340473272996975
GO:0001671	ATPase activator activity	2/258	27/18639	0.0740740740740741	5.35142118863049	0.0533972058582213	0.340473272996975
GO:0004364	glutathione transferase activity	2/258	27/18639	0.0740740740740741	5.35142118863049	0.0533972058582213	0.340473272996975
GO:0015252	proton channel activity	2/258	27/18639	0.0740740740740741	5.35142118863049	0.0533972058582213	0.340473272996975
GO:0015179	L-amino acid transmembrane transporter activity	3/258	62/18639	0.0483870967741935	3.4956864216054	0.0546072503620524	0.34477518856041
GO:0005507	copper ion binding	3/258	63/18639	0.0476190476190476	3.44019933554817	0.0567734522631127	0.352918995101512
GO:0097718	disordered domain specific binding	2/258	28/18639	0.0714285714285714	5.16029900332226	0.0569931296437225	0.352918995101512
GO:0042277	peptide binding	7/258	249/18639	0.0281124497991968	2.03096105351639	0.0586695894073335	0.359840148364979
GO:0004629	phospholipase C activity	2/258	29/18639	0.0689655172413793	4.98235765838011	0.0606709407954717	0.365159681049381
GO:0043236	laminin binding	2/258	29/18639	0.0689655172413793	4.98235765838011	0.0606709407954717	0.365159681049381
GO:0001968	fibronectin binding	2/258	30/18639	0.0666666666666667	4.81627906976744	0.0644277033472812	0.379630629202839
GO:0048019	receptor antagonist activity	2/258	30/18639	0.0666666666666667	4.81627906976744	0.0644277033472812	0.379630629202839
GO:0016500	protein-hormone receptor activity	3/258	67/18639	0.0447761194029851	3.23481430059007	0.0658372947360401	0.379630629202839
GO:0050840	extracellular matrix binding	3/258	67/18639	0.0447761194029851	3.23481430059007	0.0658372947360401	0.379630629202839
GO:0140375	immune receptor activity	5/258	156/18639	0.032051282051282	2.31551878354204	0.066022718122233	0.379630629202839
GO:0005452	solute:inorganic anion antiporter activity	2/258	31/18639	0.0645161290322581	4.6609152288072	0.0682605463605818	0.389024706692165
GO:0099106	ion channel regulator activity	5/258	160/18639	0.03125	2.25763081395349	0.0718906387965177	0.395250237559593
GO:0071813	lipoprotein particle binding	2/258	32/18639	0.0625	4.51526162790698	0.072166662698327	0.395250237559593
GO:0071814	protein-lipid complex binding	2/258	32/18639	0.0625	4.51526162790698	0.072166662698327	0.395250237559593
GO:0140142	nucleocytoplasmic carrier activity	2/258	32/18639	0.0625	4.51526162790698	0.072166662698327	0.395250237559593
GO:0051020	GTPase binding	8/258	315/18639	0.0253968253968254	1.83477297895903	0.0724216273789317	0.395250237559593
GO:0097110	scaffold protein binding	3/258	70/18639	0.0428571428571429	3.09617940199336	0.0730422589453665	0.395287518998454
GO:0019956	chemokine binding	2/258	33/18639	0.0606060606060606	4.3784355179704	0.0761433078201711	0.405258596993307
GO:0030296	protein tyrosine kinase activator activity	2/258	33/18639	0.0606060606060606	4.3784355179704	0.0761433078201711	0.405258596993307
GO:0090482	vitamin transmembrane transporter activity	2/258	34/18639	0.0588235294117647	4.24965800273598	0.0801877985985705	0.423286412274421
GO:0005154	epidermal growth factor receptor binding	2/258	35/18639	0.0571428571428571	4.12823920265781	0.0842975121554619	0.438618386222328
GO:0016247	channel regulator activity	5/258	168/18639	0.0297619047619048	2.15012458471761	0.0844544718813178	0.438618386222328
GO:0003725	double-stranded RNA binding	3/258	75/18639	0.04	2.88976744186047	0.0857893172763539	0.438982758196423
GO:0005543	phospholipid binding	11/258	497/18639	0.0221327967806841	1.59896588835338	0.0858879309514741	0.438982758196423
GO:0141108	transporter regulator activity	5/258	170/18639	0.0294117647058824	2.12482900136799	0.0877654871849087	0.445047037378592
GO:0003779	actin binding	10/258	443/18639	0.0225733634311512	1.63079426741561	0.0893115386100147	0.446834738000279
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	4/258	122/18639	0.0327868852459016	2.36866183759055	0.0895057161522297	0.446834738000279
GO:0046873	metal ion transmembrane transporter activity	10/258	450/18639	0.0222222222222222	1.60542635658915	0.0964965393438989	0.466948418275563
GO:0016835	carbon-oxygen lyase activity	3/258	79/18639	0.0379746835443038	2.74345010303209	0.0966165662604149	0.466948418275563
GO:0031267	small GTPase binding	7/258	283/18639	0.0247349823321555	1.78695866546142	0.0991842538047622	0.466948418275563
GO:0015101	organic cation transmembrane transporter activity	3/258	81/18639	0.037037037037037	2.67571059431525	0.102228776261214	0.466948418275563
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	4/258	132/18639	0.0303030303030303	2.1892177589852	0.111074976412125	0.466948418275563
GO:0035198	miRNA binding	2/258	42/18639	0.0476190476190476	3.44019933554817	0.114683556469419	0.466948418275563
GO:0051087	protein-folding chaperone binding	4/258	134/18639	0.0298507462686567	2.15654286706005	0.11564440787569	0.466948418275563
GO:0016209	antioxidant activity	3/258	86/18639	0.0348837209302326	2.52014602487831	0.116804377001085	0.466948418275563
GO:0008200	ion channel inhibitor activity	2/258	43/18639	0.0465116279069767	3.36019469983775	0.119227490410279	0.466948418275563
GO:0046943	carboxylic acid transmembrane transporter activity	5/258	188/18639	0.0265957446808511	1.92138792676893	0.120501285548539	0.466948418275563
GO:0005342	organic acid transmembrane transporter activity	5/258	189/18639	0.0264550264550265	1.91122185308232	0.122468821774047	0.466948418275563
GO:0004197	cysteine-type endopeptidase activity	3/258	88/18639	0.0340909090909091	2.46286997885835	0.122841246417451	0.466948418275563
GO:0016248	channel inhibitor activity	2/258	44/18639	0.0454545454545455	3.2838266384778	0.123815570264167	0.466948418275563
GO:0030020	extracellular matrix structural constituent conferring tensile strength	2/258	44/18639	0.0454545454545455	3.2838266384778	0.123815570264167	0.466948418275563
GO:0030547	signaling receptor inhibitor activity	2/258	44/18639	0.0454545454545455	3.2838266384778	0.123815570264167	0.466948418275563
GO:0016887	ATP hydrolysis activity	9/258	417/18639	0.0215827338129496	1.55922703697507	0.126246462285106	0.466948418275563
GO:0046915	transition metal ion transmembrane transporter activity	2/258	45/18639	0.0444444444444444	3.21085271317829	0.128445715956469	0.466948418275563
GO:0140303	intramembrane lipid transporter activity	2/258	45/18639	0.0444444444444444	3.21085271317829	0.128445715956469	0.466948418275563
GO:0141110	transporter inhibitor activity	2/258	45/18639	0.0444444444444444	3.21085271317829	0.128445715956469	0.466948418275563
GO:0042393	histone binding	6/258	247/18639	0.0242914979757085	1.75491949910555	0.129095653519101	0.466948418275563
GO:0004713	protein tyrosine kinase activity	4/258	140/18639	0.0285714285714286	2.0641196013289	0.129833657389622	0.466948418275563
GO:0004862	cAMP-dependent protein kinase inhibitor activity	1/258	10/18639	0.1	7.22441860465116	0.130137627654913	0.466948418275563
GO:0004935	adrenergic receptor activity	1/258	10/18639	0.1	7.22441860465116	0.130137627654913	0.466948418275563
GO:0005381	iron ion transmembrane transporter activity	1/258	10/18639	0.1	7.22441860465116	0.130137627654913	0.466948418275563
GO:0015187	glycine transmembrane transporter activity	1/258	10/18639	0.1	7.22441860465116	0.130137627654913	0.466948418275563
GO:0019531	oxalate transmembrane transporter activity	1/258	10/18639	0.1	7.22441860465116	0.130137627654913	0.466948418275563
GO:0030957	Tat protein binding	1/258	10/18639	0.1	7.22441860465116	0.130137627654913	0.466948418275563
GO:0032395	MHC class II receptor activity	1/258	10/18639	0.1	7.22441860465116	0.130137627654913	0.466948418275563
GO:0035374	chondroitin sulfate binding	1/258	10/18639	0.1	7.22441860465116	0.130137627654913	0.466948418275563
GO:0043208	glycosphingolipid binding	1/258	10/18639	0.1	7.22441860465116	0.130137627654913	0.466948418275563
GO:0043295	glutathione binding	1/258	10/18639	0.1	7.22441860465116	0.130137627654913	0.466948418275563
GO:0045322	unmethylated CpG binding	1/258	10/18639	0.1	7.22441860465116	0.130137627654913	0.466948418275563
GO:0072582	17-beta-hydroxysteroid dehydrogenase (NADP+) activity	1/258	10/18639	0.1	7.22441860465116	0.130137627654913	0.466948418275563
GO:0030291	protein serine/threonine kinase inhibitor activity	2/258	46/18639	0.0434782608695652	3.14105156723964	0.133115896130358	0.466948418275563
GO:0001784	phosphotyrosine residue binding	2/258	47/18639	0.0425531914893617	3.07422068283028	0.137824127205417	0.466948418275563
GO:0043495	protein-membrane adaptor activity	2/258	47/18639	0.0425531914893617	3.07422068283028	0.137824127205417	0.466948418275563
GO:0051219	phosphoprotein binding	3/258	93/18639	0.032258064516129	2.3304576144036	0.138411463512829	0.466948418275563
GO:0000099	sulfur amino acid transmembrane transporter activity	1/258	11/18639	0.0909090909090909	6.5676532769556	0.142184677526889	0.466948418275563
GO:0003953	NAD+ nucleosidase activity	1/258	11/18639	0.0909090909090909	6.5676532769556	0.142184677526889	0.466948418275563
GO:0004016	adenylate cyclase activity	1/258	11/18639	0.0909090909090909	6.5676532769556	0.142184677526889	0.466948418275563
GO:0008172	S-methyltransferase activity	1/258	11/18639	0.0909090909090909	6.5676532769556	0.142184677526889	0.466948418275563
GO:0032794	GTPase activating protein binding	1/258	11/18639	0.0909090909090909	6.5676532769556	0.142184677526889	0.466948418275563
GO:0034713	type I transforming growth factor beta receptor binding	1/258	11/18639	0.0909090909090909	6.5676532769556	0.142184677526889	0.466948418275563
GO:0042608	T cell receptor binding	1/258	11/18639	0.0909090909090909	6.5676532769556	0.142184677526889	0.466948418275563
GO:0050786	RAGE receptor binding	1/258	11/18639	0.0909090909090909	6.5676532769556	0.142184677526889	0.466948418275563
GO:0070990	snRNP binding	1/258	11/18639	0.0909090909090909	6.5676532769556	0.142184677526889	0.466948418275563
GO:0099528	G protein-coupled neurotransmitter receptor activity	1/258	11/18639	0.0909090909090909	6.5676532769556	0.142184677526889	0.466948418275563
GO:0140031	phosphorylation-dependent protein binding	1/258	11/18639	0.0909090909090909	6.5676532769556	0.142184677526889	0.466948418275563
GO:1900750	oligopeptide binding	1/258	11/18639	0.0909090909090909	6.5676532769556	0.142184677526889	0.466948418275563
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	2/258	48/18639	0.0416666666666667	3.01017441860465	0.142568472452832	0.466948418275563
GO:0016829	lyase activity	5/258	200/18639	0.025	1.80610465116279	0.145074106854456	0.466948418275563
GO:0005004	GPI-linked ephrin receptor activity	2/258	49/18639	0.0408163265306122	2.94874228761272	0.147347041086871	0.466948418275563
GO:0005008	hepatocyte growth factor receptor activity	2/258	49/18639	0.0408163265306122	2.94874228761272	0.147347041086871	0.466948418275563
GO:0005009	insulin receptor activity	2/258	49/18639	0.0408163265306122	2.94874228761272	0.147347041086871	0.466948418275563
GO:0005011	macrophage colony-stimulating factor receptor activity	2/258	49/18639	0.0408163265306122	2.94874228761272	0.147347041086871	0.466948418275563
GO:0005018	platelet-derived growth factor alpha-receptor activity	2/258	49/18639	0.0408163265306122	2.94874228761272	0.147347041086871	0.466948418275563
GO:0005020	stem cell factor receptor activity	2/258	49/18639	0.0408163265306122	2.94874228761272	0.147347041086871	0.466948418275563
GO:0008288	boss receptor activity	2/258	49/18639	0.0408163265306122	2.94874228761272	0.147347041086871	0.466948418275563
GO:0016763	pentosyltransferase activity	2/258	49/18639	0.0408163265306122	2.94874228761272	0.147347041086871	0.466948418275563
GO:0036332	placental growth factor receptor activity	2/258	49/18639	0.0408163265306122	2.94874228761272	0.147347041086871	0.466948418275563
GO:0038062	protein tyrosine kinase collagen receptor activity	2/258	49/18639	0.0408163265306122	2.94874228761272	0.147347041086871	0.466948418275563
GO:0060175	brain-derived neurotrophic factor receptor activity	2/258	49/18639	0.0408163265306122	2.94874228761272	0.147347041086871	0.466948418275563
GO:0005007	fibroblast growth factor receptor activity	2/258	50/18639	0.04	2.88976744186047	0.152157987372382	0.466948418275563
GO:0005017	platelet-derived growth factor receptor activity	2/258	50/18639	0.04	2.88976744186047	0.152157987372382	0.466948418275563
GO:0005019	platelet-derived growth factor beta-receptor activity	2/258	50/18639	0.04	2.88976744186047	0.152157987372382	0.466948418275563
GO:0000340	RNA 7-methylguanosine cap binding	1/258	12/18639	0.0833333333333333	6.0203488372093	0.15406552105266	0.466948418275563
GO:0004300	enoyl-CoA hydratase activity	1/258	12/18639	0.0833333333333333	6.0203488372093	0.15406552105266	0.466948418275563
GO:0005078	MAP-kinase scaffold activity	1/258	12/18639	0.0833333333333333	6.0203488372093	0.15406552105266	0.466948418275563
GO:0005095	GTPase inhibitor activity	1/258	12/18639	0.0833333333333333	6.0203488372093	0.15406552105266	0.466948418275563
GO:0008179	adenylate cyclase binding	1/258	12/18639	0.0833333333333333	6.0203488372093	0.15406552105266	0.466948418275563
GO:0008603	cAMP-dependent protein kinase regulator activity	1/258	12/18639	0.0833333333333333	6.0203488372093	0.15406552105266	0.466948418275563
GO:0015132	prostaglandin transmembrane transporter activity	1/258	12/18639	0.0833333333333333	6.0203488372093	0.15406552105266	0.466948418275563
GO:0015269	calcium-activated potassium channel activity	1/258	12/18639	0.0833333333333333	6.0203488372093	0.15406552105266	0.466948418275563
GO:0016208	AMP binding	1/258	12/18639	0.0833333333333333	6.0203488372093	0.15406552105266	0.466948418275563
GO:0034452	dynactin binding	1/258	12/18639	0.0833333333333333	6.0203488372093	0.15406552105266	0.466948418275563
GO:0042301	phosphate ion binding	1/258	12/18639	0.0833333333333333	6.0203488372093	0.15406552105266	0.466948418275563
GO:0045295	gamma-catenin binding	1/258	12/18639	0.0833333333333333	6.0203488372093	0.15406552105266	0.466948418275563
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	1/258	12/18639	0.0833333333333333	6.0203488372093	0.15406552105266	0.466948418275563
GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	1/258	12/18639	0.0833333333333333	6.0203488372093	0.15406552105266	0.466948418275563
GO:0140822	NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity	1/258	12/18639	0.0833333333333333	6.0203488372093	0.15406552105266	0.466948418275563
GO:0140844	NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity	1/258	12/18639	0.0833333333333333	6.0203488372093	0.15406552105266	0.466948418275563
GO:0140867	NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity	1/258	12/18639	0.0833333333333333	6.0203488372093	0.15406552105266	0.466948418275563
GO:0005010	insulin-like growth factor receptor activity	2/258	51/18639	0.0392156862745098	2.83310533515732	0.15699950974804	0.466948418275563
GO:0005030	neurotrophin receptor activity	2/258	51/18639	0.0392156862745098	2.83310533515732	0.15699950974804	0.466948418275563
GO:0005516	calmodulin binding	5/258	207/18639	0.0241545893719807	1.74502864846646	0.160327711435292	0.466948418275563
GO:0005080	protein kinase C binding	2/258	52/18639	0.0384615384615385	2.77862254025045	0.161869849965081	0.466948418275563
GO:0030159	signaling receptor complex adaptor activity	2/258	52/18639	0.0384615384615385	2.77862254025045	0.161869849965081	0.466948418275563
GO:0002161	aminoacyl-tRNA editing activity	1/258	13/18639	0.0769230769230769	5.55724508050089	0.165782442487588	0.466948418275563
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	1/258	13/18639	0.0769230769230769	5.55724508050089	0.165782442487588	0.466948418275563
GO:0008035	high-density lipoprotein particle binding	1/258	13/18639	0.0769230769230769	5.55724508050089	0.165782442487588	0.466948418275563
GO:0043560	insulin receptor substrate binding	1/258	13/18639	0.0769230769230769	5.55724508050089	0.165782442487588	0.466948418275563
GO:0051011	microtubule minus-end binding	1/258	13/18639	0.0769230769230769	5.55724508050089	0.165782442487588	0.466948418275563
GO:0052650	all-trans-retinol dehydrogenase (NADP+) activity	1/258	13/18639	0.0769230769230769	5.55724508050089	0.165782442487588	0.466948418275563
GO:0071714	icosanoid transmembrane transporter activity	1/258	13/18639	0.0769230769230769	5.55724508050089	0.165782442487588	0.466948418275563
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	1/258	13/18639	0.0769230769230769	5.55724508050089	0.165782442487588	0.466948418275563
GO:0140806	NAD+-protein-aspartate ADP-ribosyltransferase activity	1/258	13/18639	0.0769230769230769	5.55724508050089	0.165782442487588	0.466948418275563
GO:0005003	ephrin receptor activity	2/258	53/18639	0.0377358490566038	2.72619569986836	0.166767292241273	0.466948418275563
GO:0005005	transmembrane-ephrin receptor activity	2/258	53/18639	0.0377358490566038	2.72619569986836	0.166767292241273	0.466948418275563
GO:0016860	intramolecular oxidoreductase activity	2/258	53/18639	0.0377358490566038	2.72619569986836	0.166767292241273	0.466948418275563
GO:0017046	peptide hormone binding	2/258	53/18639	0.0377358490566038	2.72619569986836	0.166767292241273	0.466948418275563
GO:0038064	collagen receptor activity	2/258	53/18639	0.0377358490566038	2.72619569986836	0.166767292241273	0.466948418275563
GO:0015171	amino acid transmembrane transporter activity	3/258	102/18639	0.0294117647058824	2.12482900136799	0.167972491395145	0.468286945707678
GO:0051287	NAD binding	2/258	54/18639	0.037037037037037	2.67571059431525	0.171690162429853	0.474542766544314
GO:0140463	chromatin-protein adaptor activity	2/258	54/18639	0.037037037037037	2.67571059431525	0.171690162429853	0.474542766544314
GO:0008374	O-acyltransferase activity	2/258	55/18639	0.0363636363636364	2.62706131078224	0.176636827203199	0.47585614775183
GO:0098632	cell-cell adhesion mediator activity	2/258	55/18639	0.0363636363636364	2.62706131078224	0.176636827203199	0.47585614775183
GO:0008559	ABC-type xenobiotic transporter activity	1/258	14/18639	0.0714285714285714	5.16029900332226	0.177337694814347	0.47585614775183
GO:0015926	glucosidase activity	1/258	14/18639	0.0714285714285714	5.16029900332226	0.177337694814347	0.47585614775183
GO:0030283	testosterone dehydrogenase [NAD(P)+] activity	1/258	14/18639	0.0714285714285714	5.16029900332226	0.177337694814347	0.47585614775183
GO:0061665	SUMO ligase activity	1/258	14/18639	0.0714285714285714	5.16029900332226	0.177337694814347	0.47585614775183
GO:1901612	cardiolipin binding	1/258	14/18639	0.0714285714285714	5.16029900332226	0.177337694814347	0.47585614775183
GO:0008013	beta-catenin binding	3/258	106/18639	0.0283018867924528	2.04464677490127	0.181657942751486	0.48231894487736
GO:0004601	peroxidase activity	2/258	57/18639	0.0350877192982456	2.53488372093023	0.186595206492533	0.48231894487736
GO:0000774	adenyl-nucleotide exchange factor activity	1/258	15/18639	0.0666666666666667	4.81627906976744	0.188733500169402	0.48231894487736
GO:0004089	carbonate dehydratase activity	1/258	15/18639	0.0666666666666667	4.81627906976744	0.188733500169402	0.48231894487736
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	1/258	15/18639	0.0666666666666667	4.81627906976744	0.188733500169402	0.48231894487736
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	1/258	15/18639	0.0666666666666667	4.81627906976744	0.188733500169402	0.48231894487736
GO:0031386	protein tag activity	1/258	15/18639	0.0666666666666667	4.81627906976744	0.188733500169402	0.48231894487736
GO:0048531	beta-1,3-galactosyltransferase activity	1/258	15/18639	0.0666666666666667	4.81627906976744	0.188733500169402	0.48231894487736
GO:0061578	K63-linked deubiquitinase activity	1/258	15/18639	0.0666666666666667	4.81627906976744	0.188733500169402	0.48231894487736
GO:0120283	protein serine/threonine kinase binding	1/258	15/18639	0.0666666666666667	4.81627906976744	0.188733500169402	0.48231894487736
GO:0140776	protein-containing complex destabilizing activity	1/258	15/18639	0.0666666666666667	4.81627906976744	0.188733500169402	0.48231894487736
GO:0141047	molecular tag activity	1/258	15/18639	0.0666666666666667	4.81627906976744	0.188733500169402	0.48231894487736
GO:0061980	regulatory RNA binding	2/258	58/18639	0.0344827586206897	2.49117882919006	0.191603851303264	0.483700165045184
GO:0004620	phospholipase activity	3/258	109/18639	0.0275229357798165	1.98837209302326	0.192112538956533	0.483700165045184
GO:0015081	sodium ion transmembrane transporter activity	4/258	164/18639	0.024390243902439	1.7620533182076	0.192898908944309	0.483700165045184
GO:0015103	inorganic anion transmembrane transporter activity	4/258	165/18639	0.0242424242424242	1.75137420718816	0.195713422044055	0.483700165045184
GO:0004879	nuclear receptor activity	2/258	59/18639	0.0338983050847458	2.44895545920378	0.196630149754791	0.483700165045184
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	2/258	59/18639	0.0338983050847458	2.44895545920378	0.196630149754791	0.483700165045184
GO:0031593	polyubiquitin modification-dependent protein binding	2/258	59/18639	0.0338983050847458	2.44895545920378	0.196630149754791	0.483700165045184
GO:0045309	protein phosphorylated amino acid binding	2/258	59/18639	0.0338983050847458	2.44895545920378	0.196630149754791	0.483700165045184
GO:0003688	DNA replication origin binding	1/258	16/18639	0.0625	4.51526162790698	0.199972050263705	0.483700165045184
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	1/258	16/18639	0.0625	4.51526162790698	0.199972050263705	0.483700165045184
GO:0061809	NAD+ nucleosidase activity, cyclic ADP-ribose generating	1/258	16/18639	0.0625	4.51526162790698	0.199972050263705	0.483700165045184
GO:0140327	flippase activity	1/258	16/18639	0.0625	4.51526162790698	0.199972050263705	0.483700165045184
GO:0016874	ligase activity	4/258	167/18639	0.0239520958083832	1.73039966578471	0.201380308030261	0.483700165045184
GO:0098531	ligand-modulated transcription factor activity	2/258	60/18639	0.0333333333333333	2.40813953488372	0.201672660868633	0.483700165045184
GO:0035091	phosphatidylinositol binding	6/258	284/18639	0.0211267605633803	1.52628562070095	0.201760384511857	0.483700165045184
GO:0004438	phosphatidylinositol-3-phosphate phosphatase activity	1/258	17/18639	0.0588235294117647	4.24965800273598	0.211055506797666	0.483700165045184
GO:0004659	prenyltransferase activity	1/258	17/18639	0.0588235294117647	4.24965800273598	0.211055506797666	0.483700165045184
GO:0005092	GDP-dissociation inhibitor activity	1/258	17/18639	0.0588235294117647	4.24965800273598	0.211055506797666	0.483700165045184
GO:0008429	phosphatidylethanolamine binding	1/258	17/18639	0.0588235294117647	4.24965800273598	0.211055506797666	0.483700165045184
GO:0015278	intracellularly gated calcium channel activity	1/258	17/18639	0.0588235294117647	4.24965800273598	0.211055506797666	0.483700165045184
GO:0015347	sodium-independent organic anion transmembrane transporter activity	1/258	17/18639	0.0588235294117647	4.24965800273598	0.211055506797666	0.483700165045184
GO:0016018	cyclosporin A binding	1/258	17/18639	0.0588235294117647	4.24965800273598	0.211055506797666	0.483700165045184
GO:0030169	low-density lipoprotein particle binding	1/258	17/18639	0.0588235294117647	4.24965800273598	0.211055506797666	0.483700165045184
GO:0030548	acetylcholine receptor regulator activity	1/258	17/18639	0.0588235294117647	4.24965800273598	0.211055506797666	0.483700165045184
GO:0031489	myosin V binding	1/258	17/18639	0.0588235294117647	4.24965800273598	0.211055506797666	0.483700165045184
GO:0032183	SUMO binding	1/258	17/18639	0.0588235294117647	4.24965800273598	0.211055506797666	0.483700165045184
GO:0032977	membrane insertase activity	1/258	17/18639	0.0588235294117647	4.24965800273598	0.211055506797666	0.483700165045184
GO:0051787	misfolded protein binding	1/258	17/18639	0.0588235294117647	4.24965800273598	0.211055506797666	0.483700165045184
GO:0070403	NAD+ binding	1/258	17/18639	0.0588235294117647	4.24965800273598	0.211055506797666	0.483700165045184
GO:0017124	SH3 domain binding	3/258	115/18639	0.0260869565217391	1.88463094034378	0.21344948688528	0.48625505171632
GO:1990782	protein tyrosine kinase binding	3/258	117/18639	0.0256410256410256	1.85241502683363	0.220673315807433	0.48625505171632
GO:0000400	four-way junction DNA binding	1/258	18/18639	0.0555555555555556	4.01356589147287	0.221986001870494	0.48625505171632
GO:0008409	5'-3' exonuclease activity	1/258	18/18639	0.0555555555555556	4.01356589147287	0.221986001870494	0.48625505171632
GO:0017075	syntaxin-1 binding	1/258	18/18639	0.0555555555555556	4.01356589147287	0.221986001870494	0.48625505171632
GO:0017128	phospholipid scramblase activity	1/258	18/18639	0.0555555555555556	4.01356589147287	0.221986001870494	0.48625505171632
GO:0031690	adrenergic receptor binding	1/258	18/18639	0.0555555555555556	4.01356589147287	0.221986001870494	0.48625505171632
GO:0035615	clathrin adaptor activity	1/258	18/18639	0.0555555555555556	4.01356589147287	0.221986001870494	0.48625505171632
GO:0050811	GABA receptor binding	1/258	18/18639	0.0555555555555556	4.01356589147287	0.221986001870494	0.48625505171632
GO:0052744	phosphatidylinositol monophosphate phosphatase activity	1/258	18/18639	0.0555555555555556	4.01356589147287	0.221986001870494	0.48625505171632
GO:0070628	proteasome binding	1/258	18/18639	0.0555555555555556	4.01356589147287	0.221986001870494	0.48625505171632
GO:0099602	neurotransmitter receptor regulator activity	1/258	18/18639	0.0555555555555556	4.01356589147287	0.221986001870494	0.48625505171632
GO:1901611	phosphatidylglycerol binding	1/258	18/18639	0.0555555555555556	4.01356589147287	0.221986001870494	0.48625505171632
GO:0038024	cargo receptor activity	2/258	65/18639	0.0307692307692308	2.22289803220036	0.227080467351675	0.493095628681828
GO:0003756	protein disulfide isomerase activity	1/258	19/18639	0.0526315789473684	3.80232558139535	0.232765638383968	0.493095628681828
GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)+] activity	1/258	19/18639	0.0526315789473684	3.80232558139535	0.232765638383968	0.493095628681828
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	1/258	19/18639	0.0526315789473684	3.80232558139535	0.232765638383968	0.493095628681828
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	1/258	19/18639	0.0526315789473684	3.80232558139535	0.232765638383968	0.493095628681828
GO:0034987	immunoglobulin receptor binding	1/258	19/18639	0.0526315789473684	3.80232558139535	0.232765638383968	0.493095628681828
GO:0043395	heparan sulfate proteoglycan binding	1/258	19/18639	0.0526315789473684	3.80232558139535	0.232765638383968	0.493095628681828
GO:0046624	sphingolipid transporter activity	1/258	19/18639	0.0526315789473684	3.80232558139535	0.232765638383968	0.493095628681828
GO:0097001	ceramide binding	1/258	19/18639	0.0526315789473684	3.80232558139535	0.232765638383968	0.493095628681828
GO:1990380	K48-linked deubiquitinase activity	1/258	19/18639	0.0526315789473684	3.80232558139535	0.232765638383968	0.493095628681828
GO:0016853	isomerase activity	4/258	180/18639	0.0222222222222222	1.60542635658915	0.239309585791609	0.502395320012281
GO:0030145	manganese ion binding	2/258	68/18639	0.0294117647058824	2.12482900136799	0.242435113052037	0.502395320012281
GO:1990841	promoter-specific chromatin binding	2/258	68/18639	0.0294117647058824	2.12482900136799	0.242435113052037	0.502395320012281
GO:0000339	RNA cap binding	1/258	20/18639	0.05	3.61220930232558	0.243396490440732	0.502395320012281
GO:0004745	all-trans-retinol dehydrogenase (NAD+) activity	1/258	20/18639	0.05	3.61220930232558	0.243396490440732	0.502395320012281
GO:0015095	magnesium ion transmembrane transporter activity	1/258	20/18639	0.05	3.61220930232558	0.243396490440732	0.502395320012281
GO:0016408	C-acyltransferase activity	1/258	20/18639	0.05	3.61220930232558	0.243396490440732	0.502395320012281
GO:0042288	MHC class I protein binding	1/258	20/18639	0.05	3.61220930232558	0.243396490440732	0.502395320012281
GO:0002039	p53 binding	2/258	69/18639	0.0289855072463768	2.09403437815976	0.247564438155233	0.509365808856133
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	1/258	21/18639	0.0476190476190476	3.44019933554817	0.253880603737165	0.512536391243682
GO:0005123	death receptor binding	1/258	21/18639	0.0476190476190476	3.44019933554817	0.253880603737165	0.512536391243682
GO:0009931	calcium-dependent protein serine/threonine kinase activity	1/258	21/18639	0.0476190476190476	3.44019933554817	0.253880603737165	0.512536391243682
GO:0009975	cyclase activity	1/258	21/18639	0.0476190476190476	3.44019933554817	0.253880603737165	0.512536391243682
GO:0051010	microtubule plus-end binding	1/258	21/18639	0.0476190476190476	3.44019933554817	0.253880603737165	0.512536391243682
GO:0140312	cargo adaptor activity	1/258	21/18639	0.0476190476190476	3.44019933554817	0.253880603737165	0.512536391243682
GO:0008234	cysteine-type peptidase activity	4/258	187/18639	0.0213903743315508	1.54533018281308	0.260385562752012	0.51977743290399
GO:0008093	cytoskeletal anchor activity	1/258	22/18639	0.0454545454545455	3.2838266384778	0.264219995950927	0.51977743290399
GO:0061133	endopeptidase activator activity	1/258	22/18639	0.0454545454545455	3.2838266384778	0.264219995950927	0.51977743290399
GO:0070034	telomerase RNA binding	1/258	22/18639	0.0454545454545455	3.2838266384778	0.264219995950927	0.51977743290399
GO:0140035	ubiquitin-like protein reader activity	1/258	22/18639	0.0454545454545455	3.2838266384778	0.264219995950927	0.51977743290399
GO:0035591	signaling adaptor activity	3/258	129/18639	0.0232558139534884	1.68009734991888	0.264908482878125	0.51977743290399
GO:0016298	lipase activity	3/258	130/18639	0.0230769230769231	1.66717352415027	0.268648322954647	0.51977743290399
GO:0016798	hydrolase activity, acting on glycosyl bonds	3/258	130/18639	0.0230769230769231	1.66717352415027	0.268648322954647	0.51977743290399
GO:0019902	phosphatase binding	4/258	190/18639	0.0210526315789474	1.52093023255814	0.269528515855404	0.51977743290399
GO:0031491	nucleosome binding	2/258	74/18639	0.027027027027027	1.95254556882464	0.273245094520971	0.51977743290399
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	1/258	23/18639	0.0434782608695652	3.14105156723964	0.274416657123224	0.51977743290399
GO:0004022	alcohol dehydrogenase (NAD+) activity	1/258	23/18639	0.0434782608695652	3.14105156723964	0.274416657123224	0.51977743290399
GO:0005283	amino acid:sodium symporter activity	1/258	23/18639	0.0434782608695652	3.14105156723964	0.274416657123224	0.51977743290399
GO:0008171	O-methyltransferase activity	1/258	23/18639	0.0434782608695652	3.14105156723964	0.274416657123224	0.51977743290399
GO:0016849	phosphorus-oxygen lyase activity	1/258	23/18639	0.0434782608695652	3.14105156723964	0.274416657123224	0.51977743290399
GO:0042171	lysophosphatidic acid acyltransferase activity	1/258	23/18639	0.0434782608695652	3.14105156723964	0.274416657123224	0.51977743290399
GO:0043274	phospholipase binding	1/258	23/18639	0.0434782608695652	3.14105156723964	0.274416657123224	0.51977743290399
GO:0070577	lysine-acetylated histone binding	1/258	23/18639	0.0434782608695652	3.14105156723964	0.274416657123224	0.51977743290399
GO:0071617	lysophospholipid acyltransferase activity	1/258	23/18639	0.0434782608695652	3.14105156723964	0.274416657123224	0.51977743290399
GO:0140103	catalytic activity, acting on a glycoprotein	1/258	23/18639	0.0434782608695652	3.14105156723964	0.274416657123224	0.51977743290399
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	1/258	23/18639	0.0434782608695652	3.14105156723964	0.274416657123224	0.51977743290399
GO:0005179	hormone activity	3/258	132/18639	0.0227272727272727	1.6419133192389	0.276145880340277	0.520455460861119
GO:0019887	protein kinase regulator activity	5/258	255/18639	0.0196078431372549	1.41655266757866	0.278905387063881	0.520455460861119
GO:0005540	hyaluronic acid binding	1/258	24/18639	0.0416666666666667	3.01017441860465	0.284472550035891	0.520455460861119
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	1/258	24/18639	0.0416666666666667	3.01017441860465	0.284472550035891	0.520455460861119
GO:0030215	semaphorin receptor binding	1/258	24/18639	0.0416666666666667	3.01017441860465	0.284472550035891	0.520455460861119
GO:0035035	histone acetyltransferase binding	1/258	24/18639	0.0416666666666667	3.01017441860465	0.284472550035891	0.520455460861119
GO:0042625	ATPase-coupled ion transmembrane transporter activity	1/258	24/18639	0.0416666666666667	3.01017441860465	0.284472550035891	0.520455460861119
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	1/258	24/18639	0.0416666666666667	3.01017441860465	0.284472550035891	0.520455460861119
GO:0046961	proton-transporting ATPase activity, rotational mechanism	1/258	24/18639	0.0416666666666667	3.01017441860465	0.284472550035891	0.520455460861119
GO:0050431	transforming growth factor beta binding	1/258	24/18639	0.0416666666666667	3.01017441860465	0.284472550035891	0.520455460861119
GO:0070840	dynein complex binding	1/258	24/18639	0.0416666666666667	3.01017441860465	0.284472550035891	0.520455460861119
GO:0140033	acetylation-dependent protein binding	1/258	24/18639	0.0416666666666667	3.01017441860465	0.284472550035891	0.520455460861119
GO:0003707	nuclear steroid receptor activity	1/258	25/18639	0.04	2.88976744186047	0.294389610583339	0.530623345844638
GO:0004709	MAP kinase kinase kinase activity	1/258	25/18639	0.04	2.88976744186047	0.294389610583339	0.530623345844638
GO:0015645	fatty acid ligase activity	1/258	25/18639	0.04	2.88976744186047	0.294389610583339	0.530623345844638
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	1/258	25/18639	0.04	2.88976744186047	0.294389610583339	0.530623345844638
GO:0120515	fatty acid-CoA ligase activity	1/258	25/18639	0.04	2.88976744186047	0.294389610583339	0.530623345844638
GO:0016922	nuclear receptor binding	3/258	137/18639	0.0218978102189781	1.58198947547106	0.294973847534752	0.530623345844638
GO:0015370	solute:sodium symporter activity	2/258	79/18639	0.0253164556962025	1.82896673535472	0.298891168933243	0.533747459950429
GO:0030295	protein kinase activator activity	3/258	139/18639	0.0215827338129496	1.55922703697507	0.302529826132745	0.533747459950429
GO:0070851	growth factor receptor binding	3/258	139/18639	0.0215827338129496	1.55922703697507	0.302529826132745	0.533747459950429
GO:0004435	phosphatidylinositol phospholipase C activity	1/258	26/18639	0.0384615384615385	2.77862254025045	0.304169748139453	0.533747459950429
GO:0005160	transforming growth factor beta receptor binding	1/258	26/18639	0.0384615384615385	2.77862254025045	0.304169748139453	0.533747459950429
GO:0005227	calcium-activated cation channel activity	1/258	26/18639	0.0384615384615385	2.77862254025045	0.304169748139453	0.533747459950429
GO:0008143	poly(A) binding	1/258	26/18639	0.0384615384615385	2.77862254025045	0.304169748139453	0.533747459950429
GO:0050681	nuclear androgen receptor binding	1/258	26/18639	0.0384615384615385	2.77862254025045	0.304169748139453	0.533747459950429
GO:0097602	cullin family protein binding	1/258	26/18639	0.0384615384615385	2.77862254025045	0.304169748139453	0.533747459950429
GO:0016757	glycosyltransferase activity	5/258	267/18639	0.0187265917602996	1.35288737914816	0.311105006819369	0.540365670513791
GO:0005044	scavenger receptor activity	1/258	27/18639	0.037037037037037	2.67571059431525	0.3138148459195	0.540365670513791
GO:0005385	zinc ion transmembrane transporter activity	1/258	27/18639	0.037037037037037	2.67571059431525	0.3138148459195	0.540365670513791
GO:0016405	CoA-ligase activity	1/258	27/18639	0.037037037037037	2.67571059431525	0.3138148459195	0.540365670513791
GO:0023026	MHC class II protein complex binding	1/258	27/18639	0.037037037037037	2.67571059431525	0.3138148459195	0.540365670513791
GO:0035255	ionotropic glutamate receptor binding	1/258	27/18639	0.037037037037037	2.67571059431525	0.3138148459195	0.540365670513791
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	1/258	27/18639	0.037037037037037	2.67571059431525	0.3138148459195	0.540365670513791
GO:0019903	protein phosphatase binding	3/258	144/18639	0.0208333333333333	1.50508720930233	0.321453509474043	0.547953774476595
GO:0005096	GTPase activator activity	5/258	271/18639	0.018450184501845	1.33291856174376	0.321957729520126	0.547953774476595
GO:0019789	SUMO transferase activity	1/258	28/18639	0.0357142857142857	2.58014950166113	0.323326761337121	0.547953774476595
GO:0045499	chemorepellent activity	1/258	28/18639	0.0357142857142857	2.58014950166113	0.323326761337121	0.547953774476595
GO:0046625	sphingolipid binding	1/258	28/18639	0.0357142857142857	2.58014950166113	0.323326761337121	0.547953774476595
GO:0046875	ephrin receptor binding	1/258	28/18639	0.0357142857142857	2.58014950166113	0.323326761337121	0.547953774476595
GO:0004860	protein kinase inhibitor activity	2/258	84/18639	0.0238095238095238	1.72009966777409	0.324391293697591	0.548314942627949
GO:0003785	actin monomer binding	1/258	29/18639	0.0344827586206897	2.49117882919006	0.332707326356466	0.550984991638837
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	1/258	29/18639	0.0344827586206897	2.49117882919006	0.332707326356466	0.550984991638837
GO:0005416	amino acid:monoatomic cation symporter activity	1/258	29/18639	0.0344827586206897	2.49117882919006	0.332707326356466	0.550984991638837
GO:0051861	glycolipid binding	1/258	29/18639	0.0344827586206897	2.49117882919006	0.332707326356466	0.550984991638837
GO:0097472	cyclin-dependent protein kinase activity	1/258	29/18639	0.0344827586206897	2.49117882919006	0.332707326356466	0.550984991638837
GO:0099604	ligand-gated calcium channel activity	1/258	29/18639	0.0344827586206897	2.49117882919006	0.332707326356466	0.550984991638837
GO:0106222	lncRNA binding	1/258	29/18639	0.0344827586206897	2.49117882919006	0.332707326356466	0.550984991638837
GO:0015085	calcium ion transmembrane transporter activity	3/258	147/18639	0.0204081632653061	1.47437114380636	0.33281546855203	0.550984991638837
GO:0019209	kinase activator activity	3/258	148/18639	0.0202702702702703	1.46440917661848	0.336601855490988	0.555824602400504
GO:0008081	phosphoric diester hydrolase activity	2/258	87/18639	0.0229885057471264	1.6607858861267	0.339580662265524	0.556114080829961
GO:0008509	monoatomic anion transmembrane transporter activity	3/258	149/18639	0.0201342281879195	1.45458092711097	0.340387179313236	0.556114080829961
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	1/258	30/18639	0.0333333333333333	2.40813953488372	0.341958347839541	0.556114080829961
GO:0008106	alcohol dehydrogenase (NADP+) activity	1/258	30/18639	0.0333333333333333	2.40813953488372	0.341958347839541	0.556114080829961
GO:0022839	monoatomic ion-gated channel activity	1/258	30/18639	0.0333333333333333	2.40813953488372	0.341958347839541	0.556114080829961
GO:0031624	ubiquitin conjugating enzyme binding	1/258	30/18639	0.0333333333333333	2.40813953488372	0.341958347839541	0.556114080829961
GO:0003727	single-stranded RNA binding	2/258	89/18639	0.0224719101123595	1.62346485497779	0.34964914484605	0.558772984422501
GO:0005310	dicarboxylic acid transmembrane transporter activity	1/258	31/18639	0.032258064516129	2.3304576144036	0.35108160788884	0.558772984422501
GO:0016411	acylglycerol O-acyltransferase activity	1/258	31/18639	0.032258064516129	2.3304576144036	0.35108160788884	0.558772984422501
GO:0016878	acid-thiol ligase activity	1/258	31/18639	0.032258064516129	2.3304576144036	0.35108160788884	0.558772984422501
GO:0017147	Wnt-protein binding	1/258	31/18639	0.032258064516129	2.3304576144036	0.35108160788884	0.558772984422501
GO:0047499	calcium-independent phospholipase A2 activity	1/258	31/18639	0.032258064516129	2.3304576144036	0.35108160788884	0.558772984422501
GO:0072349	modified amino acid transmembrane transporter activity	1/258	31/18639	0.032258064516129	2.3304576144036	0.35108160788884	0.558772984422501
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	6/258	349/18639	0.0171919770773639	1.24202039048444	0.353864550132379	0.558772984422501
GO:0019210	kinase inhibitor activity	2/258	90/18639	0.0222222222222222	1.60542635658915	0.354664134555198	0.558772984422501
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	2/258	91/18639	0.021978021978022	1.58778430871454	0.359665481493218	0.558772984422501
GO:0072341	modified amino acid binding	2/258	91/18639	0.021978021978022	1.58778430871454	0.359665481493218	0.558772984422501
GO:0008378	galactosyltransferase activity	1/258	32/18639	0.03125	2.25763081395349	0.360078864185308	0.558772984422501
GO:0015106	bicarbonate transmembrane transporter activity	1/258	32/18639	0.03125	2.25763081395349	0.360078864185308	0.558772984422501
GO:0031369	translation initiation factor binding	1/258	32/18639	0.03125	2.25763081395349	0.360078864185308	0.558772984422501
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	1/258	32/18639	0.03125	2.25763081395349	0.360078864185308	0.558772984422501
GO:0042910	xenobiotic transmembrane transporter activity	1/258	32/18639	0.03125	2.25763081395349	0.360078864185308	0.558772984422501
GO:0043425	bHLH transcription factor binding	1/258	32/18639	0.03125	2.25763081395349	0.360078864185308	0.558772984422501
GO:0047498	calcium-dependent phospholipase A2 activity	1/258	32/18639	0.03125	2.25763081395349	0.360078864185308	0.558772984422501
GO:0070717	poly-purine tract binding	1/258	32/18639	0.03125	2.25763081395349	0.360078864185308	0.558772984422501
GO:0015291	secondary active transmembrane transporter activity	5/258	287/18639	0.0174216027874564	1.25860951300543	0.36571004850156	0.564789619268597
GO:0019207	kinase regulator activity	5/258	287/18639	0.0174216027874564	1.25860951300543	0.36571004850156	0.564789619268597
GO:0071889	14-3-3 protein binding	1/258	33/18639	0.0303030303030303	2.1892177589852	0.368951850321719	0.567076352284455
GO:0140416	transcription regulator inhibitor activity	1/258	33/18639	0.0303030303030303	2.1892177589852	0.368951850321719	0.567076352284455
GO:0008376	acetylgalactosaminyltransferase activity	1/258	34/18639	0.0294117647058824	2.12482900136799	0.377702276131511	0.575036089429534
GO:0015035	protein-disulfide reductase activity	1/258	34/18639	0.0294117647058824	2.12482900136799	0.377702276131511	0.575036089429534
GO:0016831	carboxy-lyase activity	1/258	34/18639	0.0294117647058824	2.12482900136799	0.377702276131511	0.575036089429534
GO:0052866	phosphatidylinositol phosphate phosphatase activity	1/258	34/18639	0.0294117647058824	2.12482900136799	0.377702276131511	0.575036089429534
GO:0008276	protein methyltransferase activity	2/258	95/18639	0.0210526315789474	1.52093023255814	0.379523069812641	0.576445417356936
GO:0015079	potassium ion transmembrane transporter activity	3/258	160/18639	0.01875	1.35457848837209	0.381858954961754	0.57859929590808
GO:0004623	phospholipase A2 activity	1/258	35/18639	0.0285714285714286	2.0641196013289	0.386331828013159	0.57859929590808
GO:0005343	organic acid:sodium symporter activity	1/258	35/18639	0.0285714285714286	2.0641196013289	0.386331828013159	0.57859929590808
GO:0016229	steroid dehydrogenase activity	1/258	35/18639	0.0285714285714286	2.0641196013289	0.386331828013159	0.57859929590808
GO:0061631	ubiquitin conjugating enzyme activity	1/258	35/18639	0.0285714285714286	2.0641196013289	0.386331828013159	0.57859929590808
GO:0140566	histone reader activity	1/258	35/18639	0.0285714285714286	2.0641196013289	0.386331828013159	0.57859929590808
GO:0004033	aldo-keto reductase (NADPH) activity	1/258	36/18639	0.0277777777777778	2.00678294573643	0.39484216925013	0.581872670473876
GO:0004869	cysteine-type endopeptidase inhibitor activity	1/258	36/18639	0.0277777777777778	2.00678294573643	0.39484216925013	0.581872670473876
GO:0005484	SNAP receptor activity	1/258	36/18639	0.0277777777777778	2.00678294573643	0.39484216925013	0.581872670473876
GO:0044390	ubiquitin-like protein conjugating enzyme binding	1/258	36/18639	0.0277777777777778	2.00678294573643	0.39484216925013	0.581872670473876
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	1/258	36/18639	0.0277777777777778	2.00678294573643	0.39484216925013	0.581872670473876
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	1/258	36/18639	0.0277777777777778	2.00678294573643	0.39484216925013	0.581872670473876
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	1/258	36/18639	0.0277777777777778	2.00678294573643	0.39484216925013	0.581872670473876
GO:0023023	MHC protein complex binding	1/258	37/18639	0.027027027027027	1.95254556882464	0.403234940326487	0.590189321750586
GO:0042805	actinin binding	1/258	37/18639	0.027027027027027	1.95254556882464	0.403234940326487	0.590189321750586
GO:0043394	proteoglycan binding	1/258	37/18639	0.027027027027027	1.95254556882464	0.403234940326487	0.590189321750586
GO:0005109	frizzled binding	1/258	38/18639	0.0263157894736842	1.90116279069767	0.411511759238204	0.599578219342542
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	1/258	38/18639	0.0263157894736842	1.90116279069767	0.411511759238204	0.599578219342542
GO:0005253	monoatomic anion channel activity	2/258	103/18639	0.0194174757281553	1.40279972905848	0.418423351834525	0.60598699291336
GO:0000217	DNA secondary structure binding	1/258	39/18639	0.0256410256410256	1.85241502683363	0.419674221800246	0.60598699291336
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	1/258	39/18639	0.0256410256410256	1.85241502683363	0.419674221800246	0.60598699291336
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	1/258	39/18639	0.0256410256410256	1.85241502683363	0.419674221800246	0.60598699291336
GO:0004532	RNA exonuclease activity	1/258	40/18639	0.025	1.80610465116279	0.427723901949469	0.612590730820851
GO:0015036	disulfide oxidoreductase activity	1/258	40/18639	0.025	1.80610465116279	0.427723901949469	0.612590730820851
GO:0030331	nuclear estrogen receptor binding	1/258	40/18639	0.025	1.80610465116279	0.427723901949469	0.612590730820851
GO:0001530	lipopolysaccharide binding	1/258	41/18639	0.024390243902439	1.7620533182076	0.435662352043401	0.612590730820851
GO:0004812	aminoacyl-tRNA ligase activity	1/258	41/18639	0.024390243902439	1.7620533182076	0.435662352043401	0.612590730820851
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	1/258	41/18639	0.024390243902439	1.7620533182076	0.435662352043401	0.612590730820851
GO:0008227	G protein-coupled amine receptor activity	1/258	41/18639	0.024390243902439	1.7620533182076	0.435662352043401	0.612590730820851
GO:0016875	ligase activity, forming carbon-oxygen bonds	1/258	41/18639	0.024390243902439	1.7620533182076	0.435662352043401	0.612590730820851
GO:0016877	ligase activity, forming carbon-sulfur bonds	1/258	41/18639	0.024390243902439	1.7620533182076	0.435662352043401	0.612590730820851
GO:0017080	sodium channel regulator activity	1/258	41/18639	0.024390243902439	1.7620533182076	0.435662352043401	0.612590730820851
GO:0042287	MHC protein binding	1/258	41/18639	0.024390243902439	1.7620533182076	0.435662352043401	0.612590730820851
GO:0061650	ubiquitin-like protein conjugating enzyme activity	1/258	41/18639	0.024390243902439	1.7620533182076	0.435662352043401	0.612590730820851
GO:0005496	steroid binding	2/258	108/18639	0.0185185185185185	1.33785529715762	0.442104325529593	0.615535065585765
GO:0008307	structural constituent of muscle	1/258	42/18639	0.0238095238095238	1.72009966777409	0.443491103154961	0.615535065585765
GO:0016859	cis-trans isomerase activity	1/258	42/18639	0.0238095238095238	1.72009966777409	0.443491103154961	0.615535065585765
GO:0031492	nucleosomal DNA binding	1/258	42/18639	0.0238095238095238	1.72009966777409	0.443491103154961	0.615535065585765
GO:0042056	chemoattractant activity	1/258	42/18639	0.0238095238095238	1.72009966777409	0.443491103154961	0.615535065585765
GO:0048487	beta-tubulin binding	1/258	42/18639	0.0238095238095238	1.72009966777409	0.443491103154961	0.615535065585765
GO:0005319	lipid transporter activity	3/258	178/18639	0.0168539325842697	1.21759864123334	0.448280871161244	0.620844905436218
GO:0005245	voltage-gated calcium channel activity	1/258	43/18639	0.0232558139534884	1.68009734991888	0.451211665363168	0.622525875572672
GO:0004222	metalloendopeptidase activity	2/258	110/18639	0.0181818181818182	1.31353065539112	0.451427925298816	0.622525875572672
GO:0140104	molecular carrier activity	4/258	249/18639	0.0160642570281124	1.16054917343794	0.453123420841446	0.623528809875836
GO:0005200	structural constituent of cytoskeleton	2/258	112/18639	0.0178571428571429	1.29007475083056	0.460662824528999	0.632551938159222
GO:0042605	peptide antigen binding	1/258	45/18639	0.0222222222222222	1.60542635658915	0.466334160132694	0.638977019415861
GO:1901981	phosphatidylinositol phosphate binding	3/258	185/18639	0.0162162162162162	1.17152734129478	0.473360708511831	0.644467567167848
GO:0003713	transcription coactivator activity	4/258	256/18639	0.015625	1.12881540697674	0.474334659299043	0.644467567167848
GO:0035401	histone H3Y41 kinase activity	2/258	115/18639	0.0173913043478261	1.25642062689585	0.474344141052112	0.644467567167848
GO:0140801	histone H2AXY142 kinase activity	2/258	115/18639	0.0173913043478261	1.25642062689585	0.474344141052112	0.644467567167848
GO:0015294	solute:monoatomic cation symporter activity	2/258	116/18639	0.0172413793103448	1.24558941459503	0.478857985152246	0.649230615659044
GO:0031406	carboxylic acid binding	3/258	187/18639	0.0160427807486631	1.15899763710981	0.480431997786836	0.649456459310654
GO:0140359	ABC-type transporter activity	1/258	47/18639	0.0212765957446809	1.53711034141514	0.481041507905562	0.649456459310654
GO:0043177	organic acid binding	3/258	189/18639	0.0158730158730159	1.14673311184939	0.487458694900699	0.656426997562169
GO:0038187	pattern recognition receptor activity	1/258	48/18639	0.0208333333333333	1.50508720930233	0.488243061851365	0.656426997562169
GO:0004175	endopeptidase activity	6/258	405/18639	0.0148148148148148	1.0702842377261	0.490981658167358	0.658733724707872
GO:0035254	glutamate receptor binding	1/258	49/18639	0.0204081632653061	1.47437114380636	0.495345062283958	0.663206278816775
GO:0032182	ubiquitin-like protein binding	2/258	120/18639	0.0166666666666667	1.20406976744186	0.496674542159465	0.663606649690239
GO:0015108	chloride transmembrane transporter activity	2/258	121/18639	0.0165289256198347	1.19411877762829	0.501067997183079	0.668090662910772
GO:0032813	tumor necrosis factor receptor superfamily binding	1/258	50/18639	0.02	1.44488372093023	0.502348880139297	0.668414625639891
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	2/258	122/18639	0.0163934426229508	1.18433091879527	0.505436821368823	0.671136727755715
GO:0003743	translation initiation factor activity	1/258	51/18639	0.0196078431372549	1.41655266757866	0.509255867547122	0.6720507760253
GO:0005272	sodium channel activity	1/258	51/18639	0.0196078431372549	1.41655266757866	0.509255867547122	0.6720507760253
GO:0016830	carbon-carbon lyase activity	1/258	51/18639	0.0196078431372549	1.41655266757866	0.509255867547122	0.6720507760253
GO:0005261	monoatomic cation channel activity	5/258	341/18639	0.0146627565982405	1.059298915638	0.51123985846489	0.673289302354579
GO:0005267	potassium channel activity	2/258	124/18639	0.0161290322580645	1.1652288072018	0.514099938674391	0.674132613810623
GO:0016758	hexosyltransferase activity	3/258	197/18639	0.0152284263959391	1.10016526974383	0.515093757295138	0.674132613810623
GO:0140297	DNA-binding transcription factor binding	7/258	488/18639	0.014344262295082	1.03628955394586	0.515495556133486	0.674132613810623
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	1/258	52/18639	0.0192307692307692	1.38931127012522	0.516067358087946	0.674132613810623
GO:0030695	GTPase regulator activity	7/258	489/18639	0.0143149284253579	1.03417035240405	0.517664816702302	0.674850489790046
GO:0060589	nucleoside-triphosphatase regulator activity	7/258	490/18639	0.0142857142857143	1.03205980066445	0.519830652806597	0.676304930116057
GO:0004864	protein phosphatase inhibitor activity	1/258	53/18639	0.0188679245283019	1.36309784993418	0.522784667046536	0.678776866084615
GO:0019783	ubiquitin-like protein peptidase activity	2/258	127/18639	0.015748031496063	1.1377037172679	0.526906127976997	0.682751602449066
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	1/258	54/18639	0.0185185185185185	1.33785529715762	0.529409091661945	0.68324540086231
GO:0050661	NADP binding	1/258	54/18639	0.0185185185185185	1.33785529715762	0.529409091661945	0.68324540086231
GO:0140313	molecular sequestering activity	1/258	55/18639	0.0181818181818182	1.31353065539112	0.535941911374144	0.690293181849898
GO:0019212	phosphatase inhibitor activity	1/258	56/18639	0.0178571428571429	1.29007475083056	0.542384388067292	0.692937989750523
GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	1/258	56/18639	0.0178571428571429	1.29007475083056	0.542384388067292	0.692937989750523
GO:0170055	lipid transmembrane transporter activity	1/258	56/18639	0.0178571428571429	1.29007475083056	0.542384388067292	0.692937989750523
GO:0005262	calcium channel activity	2/258	131/18639	0.0152671755725191	1.10296467246583	0.543624053147151	0.692937989750523
GO:0031072	heat shock protein binding	2/258	131/18639	0.0152671755725191	1.10296467246583	0.543624053147151	0.692937989750523
GO:0141003	histone H2AX kinase activity	5/258	354/18639	0.0141242937853107	1.02039810800158	0.544451277661125	0.692937989750523
GO:0016504	peptidase activator activity	1/258	57/18639	0.0175438596491228	1.26744186046512	0.548737766309699	0.69701601874447
GO:0140996	histone H3 kinase activity	5/258	357/18639	0.0140056022408964	1.01182333398476	0.551966001335761	0.699736426890217
GO:0051015	actin filament binding	3/258	209/18639	0.0143540669856459	1.0369978858351	0.555009231529769	0.702212072898176
GO:0004674	protein serine/threonine kinase activity	6/258	433/18639	0.0138568129330254	1.0010741715452	0.556266874528748	0.702423269012772
GO:0035173	histone kinase activity	5/258	360/18639	0.0138888888888889	1.00339147286822	0.559420828530253	0.702469677909136
GO:0015297	antiporter activity	2/258	135/18639	0.0148148148148148	1.0702842377261	0.559928301848128	0.702469677909136
GO:0001786	phosphatidylserine binding	1/258	59/18639	0.0169491525423729	1.22447772960189	0.561182120553198	0.702469677909136
GO:0036002	pre-mRNA binding	1/258	59/18639	0.0169491525423729	1.22447772960189	0.561182120553198	0.702469677909136
GO:0106310	protein serine kinase activity	5/258	361/18639	0.0138504155124654	1.00061199510404	0.561892169819435	0.702469677909136
GO:0044325	transmembrane transporter binding	2/258	136/18639	0.0147058823529412	1.06241450068399	0.563939166892893	0.702469677909136
GO:0099094	ligand-gated monoatomic cation channel activity	2/258	136/18639	0.0147058823529412	1.06241450068399	0.563939166892893	0.702469677909136
GO:0042578	phosphoric ester hydrolase activity	5/258	363/18639	0.0137741046831956	0.99509898135691	0.566814090907466	0.703902548727219
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	1/258	60/18639	0.0166666666666667	1.20406976744186	0.567275501225818	0.703902548727219
GO:0019905	syntaxin binding	1/258	61/18639	0.0163934426229508	1.18433091879527	0.573284593248195	0.709990919330457
GO:0140767	enzyme-substrate adaptor activity	2/258	139/18639	0.0143884892086331	1.03948469131671	0.575814422541373	0.711755255502196
GO:0046982	protein heterodimerization activity	5/258	369/18639	0.013550135501355	0.978918510115334	0.581409666044571	0.717294683779126
GO:0020037	heme binding	2/258	142/18639	0.0140845070422535	1.01752374713397	0.587452897520124	0.72336456214715
GO:0005216	monoatomic ion channel activity	6/258	448/18639	0.0133928571428571	0.967556063122924	0.589625340627421	0.7246540445879
GO:0001664	G protein-coupled receptor binding	4/258	297/18639	0.0134680134680135	0.972985670660089	0.591075989273669	0.725053213509034
GO:0015293	symporter activity	2/258	146/18639	0.0136986301369863	0.989646384198789	0.602601574921776	0.737785958649475
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	1/258	67/18639	0.0149253731343284	1.07827143353002	0.607633022466463	0.742534471477044
GO:0005548	phospholipid transporter activity	1/258	68/18639	0.0147058823529412	1.06241450068399	0.61308373753235	0.7477763768387
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	3/258	229/18639	0.0131004366812227	0.946430384888799	0.616998499057051	0.750454794289198
GO:0098960	postsynaptic neurotransmitter receptor activity	1/258	69/18639	0.0144927536231884	1.04701718907988	0.618459021346719	0.750454794289198
GO:0000287	magnesium ion binding	3/258	230/18639	0.0130434782608696	0.942315470171891	0.619940917021511	0.750454794289198
GO:0005085	guanyl-nucleotide exchange factor activity	3/258	230/18639	0.0130434782608696	0.942315470171891	0.619940917021511	0.750454794289198
GO:0046906	tetrapyrrole binding	2/258	152/18639	0.0131578947368421	0.950581395348837	0.624533348130148	0.754595640142243
GO:0043539	protein serine/threonine kinase activator activity	1/258	73/18639	0.0136986301369863	0.989646384198789	0.63922642847263	0.763077193858489
GO:0003684	damaged DNA binding	1/258	74/18639	0.0135135135135135	0.976272784412319	0.644239871403474	0.763077193858489
GO:0017022	myosin binding	1/258	76/18639	0.0131578947368421	0.950581395348837	0.654059507249641	0.763077193858489
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	3/258	243/18639	0.0123456790123457	0.891903531438415	0.656789760315292	0.763077193858489
GO:0003724	RNA helicase activity	1/258	77/18639	0.012987012987013	0.938236182422229	0.658867601153083	0.763077193858489
GO:0008083	growth factor activity	2/258	162/18639	0.0123456790123457	0.891903531438415	0.658990883939131	0.763077193858489
GO:0004676	3-phosphoinositide-dependent protein kinase activity	3/258	245/18639	0.0122448979591837	0.884622686283816	0.662226056668944	0.763077193858489
GO:0004711	ribosomal protein S6 kinase activity	3/258	245/18639	0.0122448979591837	0.884622686283816	0.662226056668944	0.763077193858489
GO:0035175	histone H3S10 kinase activity	3/258	245/18639	0.0122448979591837	0.884622686283816	0.662226056668944	0.763077193858489
GO:0035979	histone H2AXS139 kinase activity	3/258	245/18639	0.0122448979591837	0.884622686283816	0.662226056668944	0.763077193858489
GO:0044022	histone H3S28 kinase activity	3/258	245/18639	0.0122448979591837	0.884622686283816	0.662226056668944	0.763077193858489
GO:0044023	histone H4S1 kinase activity	3/258	245/18639	0.0122448979591837	0.884622686283816	0.662226056668944	0.763077193858489
GO:0044024	histone H2AS1 kinase activity	3/258	245/18639	0.0122448979591837	0.884622686283816	0.662226056668944	0.763077193858489
GO:0044025	histone H2BS14 kinase activity	3/258	245/18639	0.0122448979591837	0.884622686283816	0.662226056668944	0.763077193858489
GO:0072354	histone H3T3 kinase activity	3/258	245/18639	0.0122448979591837	0.884622686283816	0.662226056668944	0.763077193858489
GO:0072371	histone H2AS121 kinase activity	3/258	245/18639	0.0122448979591837	0.884622686283816	0.662226056668944	0.763077193858489
GO:0072518	Rho-dependent protein serine/threonine kinase activity	3/258	245/18639	0.0122448979591837	0.884622686283816	0.662226056668944	0.763077193858489
GO:0140823	histone H2BS36 kinase activity	3/258	245/18639	0.0122448979591837	0.884622686283816	0.662226056668944	0.763077193858489
GO:0140855	histone H3S57 kinase activity	3/258	245/18639	0.0122448979591837	0.884622686283816	0.662226056668944	0.763077193858489
GO:0140995	histone H2A kinase activity	3/258	245/18639	0.0122448979591837	0.884622686283816	0.662226056668944	0.763077193858489
GO:0140997	histone H4 kinase activity	3/258	245/18639	0.0122448979591837	0.884622686283816	0.662226056668944	0.763077193858489
GO:0140998	histone H2B kinase activity	3/258	245/18639	0.0122448979591837	0.884622686283816	0.662226056668944	0.763077193858489
GO:1990244	histone H2AT120 kinase activity	3/258	245/18639	0.0122448979591837	0.884622686283816	0.662226056668944	0.763077193858489
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	6/258	484/18639	0.012396694214876	0.895589083221219	0.664016098911975	0.763077193858489
GO:0004677	DNA-dependent protein kinase activity	3/258	246/18639	0.0121951219512195	0.8810266591038	0.664920842723758	0.763077193858489
GO:0140857	histone H3T45 kinase activity	3/258	246/18639	0.0121951219512195	0.8810266591038	0.664920842723758	0.763077193858489
GO:0035402	histone H3T11 kinase activity	3/258	247/18639	0.0121457489878543	0.877459749552773	0.667600050522809	0.763077193858489
GO:0035403	histone H3T6 kinase activity	3/258	247/18639	0.0121457489878543	0.877459749552773	0.667600050522809	0.763077193858489
GO:0008186	ATP-dependent activity, acting on RNA	1/258	79/18639	0.0126582278481013	0.914483367677362	0.668284995863646	0.763077193858489
GO:0033293	monocarboxylic acid binding	1/258	79/18639	0.0126582278481013	0.914483367677362	0.668284995863646	0.763077193858489
GO:0046332	SMAD binding	1/258	79/18639	0.0126582278481013	0.914483367677362	0.668284995863646	0.763077193858489
GO:0004679	AMP-activated protein kinase activity	3/258	248/18639	0.0120967741935484	0.87392160540135	0.670263679693278	0.763981964110568
GO:0000049	tRNA binding	1/258	80/18639	0.0125	0.903052325581395	0.672896120382352	0.764277075002177
GO:0048306	calcium-dependent protein binding	1/258	80/18639	0.0125	0.903052325581395	0.672896120382352	0.764277075002177
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	2/258	167/18639	0.0119760479041916	0.865199832892355	0.675251050759193	0.764453337418478
GO:0003924	GTPase activity	4/258	331/18639	0.0120845921450151	0.873041523220684	0.675425386632164	0.764453337418478
GO:0001216	DNA-binding transcription activator activity	6/258	491/18639	0.0122199592668024	0.88282101075167	0.677463358045086	0.765414741370237
GO:0005254	chloride channel activity	1/258	83/18639	0.0120481927710843	0.870411880078453	0.686349883558982	0.771394982568908
GO:0008135	translation factor activity, RNA binding	1/258	83/18639	0.0120481927710843	0.870411880078453	0.686349883558982	0.771394982568908
GO:0030165	PDZ domain binding	1/258	83/18639	0.0120481927710843	0.870411880078453	0.686349883558982	0.771394982568908
GO:0004527	exonuclease activity	1/258	84/18639	0.0119047619047619	0.860049833887043	0.690710830424782	0.773596130075755
GO:0180051	translation factor activity	1/258	84/18639	0.0119047619047619	0.860049833887043	0.690710830424782	0.773596130075755
GO:0003823	antigen binding	2/258	174/18639	0.0114942528735632	0.830392943063352	0.69695342748727	0.779232651565628
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	1/258	86/18639	0.0116279069767442	0.840048674959438	0.699252350875341	0.780448031132963
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	3/258	268/18639	0.0111940298507463	0.808703575147518	0.720278803105071	0.802525171625719
GO:0052689	carboxylic ester hydrolase activity	1/258	92/18639	0.0108695652173913	0.785262891809909	0.723492507335229	0.804713600559391
GO:0008237	metallopeptidase activity	2/258	184/18639	0.0108695652173913	0.785262891809909	0.725866938217285	0.805962600365399
GO:0051213	dioxygenase activity	1/258	93/18639	0.010752688172043	0.7768192048012	0.727338893980374	0.806206966821619
GO:0015276	ligand-gated monoatomic ion channel activity	2/258	186/18639	0.010752688172043	0.7768192048012	0.731362707491592	0.808395062702755
GO:0016791	phosphatase activity	3/258	273/18639	0.010989010989011	0.793892154357271	0.731823480676563	0.808395062702755
GO:0005126	cytokine receptor binding	3/258	275/18639	0.0109090909090909	0.788118393234672	0.73633572349886	0.809687113668217
GO:0022834	ligand-gated channel activity	2/258	188/18639	0.0106382978723404	0.768555170707571	0.736764982313005	0.809687113668217
GO:0140597	protein carrier chaperone	2/258	188/18639	0.0106382978723404	0.768555170707571	0.736764982313005	0.809687113668217
GO:0016407	acetyltransferase activity	1/258	96/18639	0.0104166666666667	0.752543604651163	0.738561180593917	0.810278365080891
GO:0030594	neurotransmitter receptor activity	1/258	97/18639	0.0103092783505155	0.744785423159914	0.742198737375817	0.812371387204386
GO:0001217	DNA-binding transcription repressor activity	3/258	278/18639	0.0107913669064748	0.779613518487536	0.742991843266123	0.812371387204386
GO:0043130	ubiquitin binding	1/258	100/18639	0.01	0.722441860465116	0.752811674187394	0.821713081655392
GO:0008238	exopeptidase activity	1/258	102/18639	0.00980392156862745	0.70827633378933	0.759644029896698	0.827767775386588
GO:0005525	GTP binding	4/258	378/18639	0.0105820105820106	0.764488741232927	0.770961513916657	0.838681106355282
GO:0000149	SNARE binding	1/258	106/18639	0.00943396226415094	0.681548924967091	0.772749492824234	0.839208555444868
GO:0019888	protein phosphatase regulator activity	1/258	107/18639	0.00934579439252336	0.675179308845903	0.775913072970532	0.840702868158989
GO:0008168	methyltransferase activity	2/258	204/18639	0.00980392156862745	0.70827633378933	0.776736345581675	0.840702868158989
GO:0004843	cysteine-type deubiquitinase activity	1/258	108/18639	0.00925925925925926	0.668927648578811	0.779032780890541	0.841773675995819
GO:1902936	phosphatidylinositol bisphosphate binding	1/258	111/18639	0.00900900900900901	0.650848522941546	0.788134690515907	0.85018214521314
GO:0001221	transcription coregulator binding	1/258	115/18639	0.00869565217391304	0.628210313447927	0.799692188176125	0.85976923069353
GO:0101005	deubiquitinase activity	1/258	115/18639	0.00869565217391304	0.628210313447927	0.799692188176125	0.85976923069353
GO:0016741	transferase activity, transferring one-carbon groups	2/258	215/18639	0.00930232558139535	0.67203893996755	0.801054681209969	0.859798691165366
GO:0019208	phosphatase regulator activity	1/258	117/18639	0.00854700854700855	0.617471675611211	0.805233205099877	0.8623501225046
GO:0019001	guanyl nucleotide binding	4/258	400/18639	0.01	0.722441860465116	0.80744895010912	0.8623501225046
GO:0032561	guanyl ribonucleotide binding	4/258	400/18639	0.01	0.722441860465116	0.80744895010912	0.8623501225046
GO:0003697	single-stranded DNA binding	1/258	121/18639	0.00826446280991736	0.597059388814146	0.815861328979167	0.868454042748072
GO:0004540	RNA nuclease activity	1/258	121/18639	0.00826446280991736	0.597059388814146	0.815861328979167	0.868454042748072
GO:0022836	gated channel activity	3/258	318/18639	0.00943396226415094	0.681548924967091	0.819484098049994	0.870870889676891
GO:0042826	histone deacetylase binding	1/258	127/18639	0.0078740157480315	0.56885185863395	0.830729922310815	0.880967702944637
GO:0031490	chromatin DNA binding	1/258	128/18639	0.0078125	0.564407703488372	0.833089023436777	0.880967702944637
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	1/258	128/18639	0.0078125	0.564407703488372	0.833089023436777	0.880967702944637
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	1/258	130/18639	0.00769230769230769	0.555724508050089	0.837709419963892	0.884401420420896
GO:0016779	nucleotidyltransferase activity	1/258	136/18639	0.00735294117647059	0.531207250341997	0.850820002983608	0.896772638169302
GO:0140101	catalytic activity, acting on a tRNA	1/258	139/18639	0.00719424460431655	0.519742345658357	0.856974078373944	0.901783180511144
GO:0022843	voltage-gated monoatomic cation channel activity	1/258	143/18639	0.00699300699300699	0.505204098227354	0.864787869924518	0.908521024847291
GO:0008194	UDP-glycosyltransferase activity	1/258	145/18639	0.00689655172413793	0.498235765838011	0.868533799488468	0.910970304349468
GO:0000510	H3-H4 histone complex chaperone activity	1/258	151/18639	0.00662251655629139	0.478438318188819	0.879162562062288	0.914946223018131
GO:0140584	chromatin extrusion motor activity	1/258	151/18639	0.00662251655629139	0.478438318188819	0.879162562062288	0.914946223018131
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	1/258	151/18639	0.00662251655629139	0.478438318188819	0.879162562062288	0.914946223018131
GO:0140849	ATP-dependent H2AZ histone chaperone activity	1/258	151/18639	0.00662251655629139	0.478438318188819	0.879162562062288	0.914946223018131
GO:0015616	DNA translocase activity	1/258	152/18639	0.00657894736842105	0.475290697674419	0.880848848247269	0.914946223018131
GO:0140674	ATP-dependent histone chaperone activity	1/258	152/18639	0.00657894736842105	0.475290697674419	0.880848848247269	0.914946223018131
GO:0061775	cohesin loader activity	1/258	153/18639	0.0065359477124183	0.47218422252622	0.882511692253987	0.915197310485616
GO:0005506	iron ion binding	1/258	154/18639	0.00649350649350649	0.469118091211114	0.884151418717174	0.915423655392058
GO:0004386	helicase activity	1/258	155/18639	0.00645161290322581	0.46609152288072	0.885768347793234	0.915625707831208
GO:0140658	ATP-dependent chromatin remodeler activity	1/258	158/18639	0.00632911392405063	0.457241683838681	0.890485486374255	0.919026687860609
GO:0003689	DNA clamp loader activity	1/258	160/18639	0.00625	0.451526162790698	0.893521932041603	0.920684998775667
GO:0140713	histone chaperone activity	1/258	164/18639	0.00609756097560976	0.4405133295519	0.899345513867748	0.925205289026884
GO:0140098	catalytic activity, acting on RNA	3/258	387/18639	0.00775193798449612	0.560032449972958	0.906283412419719	0.93085568994944
GO:0005244	voltage-gated monoatomic ion channel activity	1/258	173/18639	0.00578034682080925	0.417596451135905	0.91131445312171	0.934532655749015
GO:0022832	voltage-gated channel activity	1/258	175/18639	0.00571428571428571	0.412823920265781	0.913775369460258	0.935043354476724
GO:0004252	serine-type endopeptidase activity	1/258	176/18639	0.00568181818181818	0.410478329809725	0.914980198028242	0.935043354476724
GO:0043021	ribonucleoprotein complex binding	1/258	177/18639	0.00564971751412429	0.408159243200631	0.916168255706231	0.935043354476724
GO:0008236	serine-type peptidase activity	1/258	194/18639	0.00515463917525773	0.372392711579957	0.934012678953764	0.951747096908583
GO:0017171	serine hydrolase activity	1/258	198/18639	0.00505050505050505	0.364869626497534	0.937628222373485	0.953921919760702
GO:0004518	nuclease activity	1/258	209/18639	0.00478468899521531	0.345665961945032	0.946585211168494	0.960514718449394
GO:0008094	ATP-dependent activity, acting on DNA	1/258	210/18639	0.00476190476190476	0.344019933554817	0.947332960247091	0.960514718449394
GO:0140097	catalytic activity, acting on DNA	2/258	336/18639	0.00595238095238095	0.430024916943522	0.948582858592879	0.960514718449394
GO:0019787	ubiquitin-like protein transferase activity	3/258	479/18639	0.00626304801670146	0.452468806136816	0.963544722269332	0.974133125810753
GO:0061659	ubiquitin-like protein ligase activity	2/258	372/18639	0.00537634408602151	0.3884096024006	0.966382081248743	0.975470313987759
GO:0016755	aminoacyltransferase activity	3/258	496/18639	0.00604838709677419	0.436960802700675	0.969598199160397	0.977185039529414
GO:0015631	tubulin binding	2/258	385/18639	0.00519480519480519	0.375294472968892	0.971219714780006	0.977289837997381
GO:0003730	mRNA 3'-UTR binding	1/258	262/18639	0.00381679389312977	0.275741168116457	0.974724402469258	0.979286295148521
GO:0008017	microtubule binding	1/258	276/18639	0.0036231884057971	0.26175429726997	0.97926493842883	0.982315608018951
GO:0004842	ubiquitin-protein transferase activity	2/258	449/18639	0.0044543429844098	0.321800383280675	0.986778581353246	0.988313229224713
GO:0061630	ubiquitin protein ligase activity	1/258	353/18639	0.0028328611898017	0.204657750839976	0.993041056064214	0.993041056064214