ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0022804 active transmembrane transporter activity 16/184 457/18639 0.0350109409190372 3.5465702597279 1.27479110369104e-05 0.00655946864372608 GO:0016209 antioxidant activity 7/184 86/18639 0.0813953488372093 8.24526036400404 2.26971233346923e-05 0.00655946864372608 GO:0015175 neutral L-amino acid transmembrane transporter activity 5/184 41/18639 0.121951219512195 12.353525980912 4.98749404254817e-05 0.0092711780357798 GO:0046943 carboxylic acid transmembrane transporter activity 9/184 188/18639 0.0478723404255319 4.84941604995375 0.000107145864737622 0.0092711780357798 GO:0015658 branched-chain amino acid transmembrane transporter activity 3/184 10/18639 0.3 30.3896739130435 0.000107926443134659 0.0092711780357798 GO:0005342 organic acid transmembrane transporter activity 9/184 189/18639 0.0476190476190476 4.82375776397515 0.000111560542610163 0.0092711780357798 GO:0004364 glutathione transferase activity 4/184 27/18639 0.148148148148148 15.0072463768116 0.000135052162706447 0.0092711780357798 GO:0015173 aromatic amino acid transmembrane transporter activity 3/184 11/18639 0.272727272727273 27.626976284585 0.000147321277084387 0.0092711780357798 GO:0001618 virus receptor activity 6/184 81/18639 0.0740740740740741 7.5036231884058 0.000149879005910576 0.0092711780357798 GO:0140272 exogenous protein binding 6/184 82/18639 0.0731707317073171 7.41211558854719 0.000160401004079235 0.0092711780357798 GO:0042277 peptide binding 10/184 249/18639 0.0401606425702811 4.06822943949712 0.000189578341528316 0.00996148012757876 GO:0015399 primary active transmembrane transporter activity 8/184 166/18639 0.0481927710843374 4.88187532739654 0.00024785402629818 0.0119383022666957 GO:0004714 transmembrane receptor protein tyrosine kinase activity 5/184 60/18639 0.0833333333333333 8.44157608695652 0.000312424051610984 0.0138908539870115 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 5/184 61/18639 0.0819672131147541 8.30318959372772 0.000337624198736093 0.0139390562049616 GO:0015179 L-amino acid transmembrane transporter activity 5/184 62/18639 0.0806451612903226 8.16926718092567 0.000364332933576443 0.0140389623738123 GO:0015171 amino acid transmembrane transporter activity 6/184 102/18639 0.0588235294117647 5.95875959079284 0.000524317876454862 0.0189409832869319 GO:0005520 insulin-like growth factor binding 3/184 19/18639 0.157894736842105 15.9945652173913 0.000816275520714492 0.0277533677042927 GO:0019199 transmembrane receptor protein kinase activity 5/184 78/18639 0.0641025641025641 6.49352006688963 0.00104690413728384 0.0336172550750033 GO:0022853 active monoatomic ion transmembrane transporter activity 6/184 118/18639 0.0508474576271186 5.15079218865144 0.00112708131487893 0.0342870000000011 GO:0015101 organic cation transmembrane transporter activity 5/184 81/18639 0.0617283950617284 6.2530193236715 0.00124075745291608 0.0358578903892747 GO:0008514 organic anion transmembrane transporter activity 9/184 269/18639 0.033457249070632 3.38918296427994 0.00144833437140676 0.0373249816569876 GO:0004602 glutathione peroxidase activity 3/184 23/18639 0.130434782608696 13.2129017013233 0.00144921347882936 0.0373249816569876 GO:0005006 epidermal growth factor receptor activity 4/184 50/18639 0.08 8.10391304347826 0.00148525013513964 0.0373249816569876 GO:0005021 vascular endothelial growth factor receptor activity 4/184 51/18639 0.0784313725490196 7.94501278772378 0.00159936884633363 0.0385181330492017 GO:0045296 cadherin binding 10/184 334/18639 0.029940119760479 3.03290158812809 0.00182952147360175 0.0412387395771822 GO:0005537 D-mannose binding 3/184 25/18639 0.12 12.1558695652174 0.00185502980797013 0.0412387395771822 GO:0004601 peroxidase activity 4/184 57/18639 0.0701754385964912 7.10869565217391 0.00241475318579276 0.0516936052366007 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 4/184 59/18639 0.0677966101694915 6.86772291820192 0.0027400942249901 0.0553991509143225 GO:0004629 phospholipase C activity 3/184 29/18639 0.103448275862069 10.4791979010495 0.00286304331694944 0.0553991509143225 GO:0042626 ATPase-coupled transmembrane transporter activity 5/184 98/18639 0.0510204081632653 5.16831188997338 0.00287538845576069 0.0553991509143225 GO:1901682 sulfur compound transmembrane transporter activity 4/184 63/18639 0.0634920634920635 6.43167701863354 0.00347846050385433 0.0648564571363808 GO:0016829 lyase activity 7/184 200/18639 0.035 3.54546195652174 0.00377503919565456 0.0681866454715105 GO:0044389 ubiquitin-like protein ligase binding 9/184 322/18639 0.0279503105590062 2.83133607885498 0.00480219803961815 0.083027071349574 GO:0000099 sulfur amino acid transmembrane transporter activity 2/184 11/18639 0.181818181818182 18.4179841897233 0.00502759082566625 0.083027071349574 GO:0008271 secondary active sulfate transmembrane transporter activity 2/184 11/18639 0.181818181818182 18.4179841897233 0.00502759082566625 0.083027071349574 GO:0046873 metal ion transmembrane transporter activity 11/184 450/18639 0.0244444444444444 2.47619565217391 0.00520788916681533 0.083169692550173 GO:0005178 integrin binding 6/184 161/18639 0.0372670807453416 3.77511477180664 0.00532401146082422 0.083169692550173 GO:0015081 sodium ion transmembrane transporter activity 6/184 164/18639 0.0365853658536585 3.70605779427359 0.0058162691791266 0.0884685154088204 GO:0005201 extracellular matrix structural constituent 6/184 168/18639 0.0357142857142857 3.61781832298137 0.00652329653542772 0.0961278856049514 GO:0051082 unfolded protein binding 5/184 121/18639 0.0413223140495868 4.18590549766439 0.00702450457317254 0.0961278856049514 GO:0017154 semaphorin receptor activity 2/184 13/18639 0.153846153846154 15.5844481605351 0.0070381892005483 0.0961278856049514 GO:0031994 insulin-like growth factor I binding 2/184 13/18639 0.153846153846154 15.5844481605351 0.0070381892005483 0.0961278856049514 GO:0140662 ATP-dependent protein folding chaperone 3/184 40/18639 0.075 7.59741847826087 0.00715138249310192 0.0961278856049514 GO:0015370 solute:sodium symporter activity 4/184 79/18639 0.0506329113924051 5.12905888827738 0.00776921229606265 0.100288669139045 GO:0015291 secondary active transmembrane transporter activity 8/184 287/18639 0.0278745644599303 2.82366308135131 0.00780794136895675 0.100288669139045 GO:0016853 isomerase activity 6/184 180/18639 0.0333333333333333 3.37663043478261 0.00901858456315305 0.11224616283528 GO:0001540 amyloid-beta binding 4/184 83/18639 0.0481927710843374 4.88187532739654 0.0092184118585592 0.11224616283528 GO:0015116 sulfate transmembrane transporter activity 2/184 15/18639 0.133333333333333 13.5065217391304 0.00935262966615041 0.11224616283528 GO:0051117 ATPase binding 4/184 84/18639 0.0476190476190476 4.82375776397515 0.00960633510974476 0.11224616283528 GO:0042605 peptide antigen binding 3/184 45/18639 0.0666666666666667 6.75326086956522 0.00990895666854125 0.11224616283528 GO:0031625 ubiquitin protein ligase binding 8/184 302/18639 0.0264900662251656 2.68341491505903 0.0104254478897166 0.11224616283528 GO:0022858 alanine transmembrane transporter activity 2/184 16/18639 0.125 12.6623641304348 0.0106198436414611 0.11224616283528 GO:0019838 growth factor binding 5/184 136/18639 0.0367647058823529 3.72422474424552 0.0113096819685411 0.11224616283528 GO:0033218 amide binding 7/184 247/18639 0.0283400809716599 2.87081939799331 0.0115137408320955 0.11224616283528 GO:0005004 GPI-linked ephrin receptor activity 3/184 49/18639 0.0612244897959184 6.20197426796806 0.0125022200745982 0.11224616283528 GO:0005008 hepatocyte growth factor receptor activity 3/184 49/18639 0.0612244897959184 6.20197426796806 0.0125022200745982 0.11224616283528 GO:0005009 insulin receptor activity 3/184 49/18639 0.0612244897959184 6.20197426796806 0.0125022200745982 0.11224616283528 GO:0005011 macrophage colony-stimulating factor receptor activity 3/184 49/18639 0.0612244897959184 6.20197426796806 0.0125022200745982 0.11224616283528 GO:0005018 platelet-derived growth factor alpha-receptor activity 3/184 49/18639 0.0612244897959184 6.20197426796806 0.0125022200745982 0.11224616283528 GO:0005020 stem cell factor receptor activity 3/184 49/18639 0.0612244897959184 6.20197426796806 0.0125022200745982 0.11224616283528 GO:0008288 boss receptor activity 3/184 49/18639 0.0612244897959184 6.20197426796806 0.0125022200745982 0.11224616283528 GO:0036332 placental growth factor receptor activity 3/184 49/18639 0.0612244897959184 6.20197426796806 0.0125022200745982 0.11224616283528 GO:0038062 protein tyrosine kinase collagen receptor activity 3/184 49/18639 0.0612244897959184 6.20197426796806 0.0125022200745982 0.11224616283528 GO:0060175 brain-derived neurotrophic factor receptor activity 3/184 49/18639 0.0612244897959184 6.20197426796806 0.0125022200745982 0.11224616283528 GO:0004713 protein tyrosine kinase activity 5/184 140/18639 0.0357142857142857 3.61781832298137 0.0126988568819774 0.11224616283528 GO:0005007 fibroblast growth factor receptor activity 3/184 50/18639 0.06 6.0779347826087 0.0132054309217976 0.11224616283528 GO:0005017 platelet-derived growth factor receptor activity 3/184 50/18639 0.06 6.0779347826087 0.0132054309217976 0.11224616283528 GO:0005019 platelet-derived growth factor beta-receptor activity 3/184 50/18639 0.06 6.0779347826087 0.0132054309217976 0.11224616283528 GO:0005010 insulin-like growth factor receptor activity 3/184 51/18639 0.0588235294117647 5.95875959079284 0.0139308098015141 0.115028686646788 GO:0005030 neurotrophin receptor activity 3/184 51/18639 0.0588235294117647 5.95875959079284 0.0139308098015141 0.115028686646788 GO:0005003 ephrin receptor activity 3/184 53/18639 0.0566037735849057 5.73390073831009 0.0154484125664454 0.120664627883857 GO:0005005 transmembrane-ephrin receptor activity 3/184 53/18639 0.0566037735849057 5.73390073831009 0.0154484125664454 0.120664627883857 GO:0016860 intramolecular oxidoreductase activity 3/184 53/18639 0.0566037735849057 5.73390073831009 0.0154484125664454 0.120664627883857 GO:0038064 collagen receptor activity 3/184 53/18639 0.0566037735849057 5.73390073831009 0.0154484125664454 0.120664627883857 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 3/184 54/18639 0.0555555555555556 5.62771739130435 0.0162407832364192 0.12516230280867 GO:0005283 amino acid:sodium symporter activity 2/184 23/18639 0.0869565217391304 8.8086011342155 0.0214026706683497 0.162772942714554 GO:0016836 hydro-lyase activity 3/184 61/18639 0.0491803278688525 4.98191375623664 0.0224185640134116 0.165991969629245 GO:0004857 enzyme inhibitor activity 9/184 416/18639 0.0216346153846154 2.19156302257525 0.0226649509934648 0.165991969629245 GO:0004620 phospholipase activity 4/184 109/18639 0.036697247706422 3.71739130434783 0.0229413192258119 0.165991969629245 GO:0016887 ATP hydrolysis activity 9/184 417/18639 0.0215827338129496 2.18630747575852 0.0229746670767121 0.165991969629245 GO:0005507 copper ion binding 3/184 63/18639 0.0476190476190476 4.82375776397515 0.0243872386201834 0.168392065274254 GO:0061134 peptidase regulator activity 6/184 226/18639 0.0265486725663717 2.68935167372066 0.0249188050360366 0.168392065274254 GO:0015645 fatty acid ligase activity 2/184 25/18639 0.08 8.10391304347826 0.0250548747639894 0.168392065274254 GO:0015662 P-type ion transporter activity 2/184 25/18639 0.08 8.10391304347826 0.0250548747639894 0.168392065274254 GO:0120515 fatty acid-CoA ligase activity 2/184 25/18639 0.08 8.10391304347826 0.0250548747639894 0.168392065274254 GO:0140358 P-type transmembrane transporter activity 2/184 25/18639 0.08 8.10391304347826 0.0250548747639894 0.168392065274254 GO:0030414 peptidase inhibitor activity 5/184 169/18639 0.029585798816568 2.99700926164137 0.0263068867735737 0.174774489139375 GO:0050750 low-density lipoprotein particle receptor binding 2/184 26/18639 0.0769230769230769 7.79222408026756 0.0269692919689128 0.17713921315945 GO:0009055 electron transfer activity 4/184 116/18639 0.0344827586206897 3.49306596701649 0.0280179971111598 0.17986873796724 GO:0015294 solute:monoatomic cation symporter activity 4/184 116/18639 0.0344827586206897 3.49306596701649 0.0280179971111598 0.17986873796724 GO:0016500 protein-hormone receptor activity 3/184 67/18639 0.0447761194029851 4.53577222582738 0.0285958818193711 0.17986873796724 GO:0001671 ATPase activator activity 2/184 27/18639 0.0740740740740741 7.5036231884058 0.0289408177006113 0.17986873796724 GO:0016405 CoA-ligase activity 2/184 27/18639 0.0740740740740741 7.5036231884058 0.0289408177006113 0.17986873796724 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 3/184 68/18639 0.0441176470588235 4.46906969309463 0.0297043984702171 0.182650450167931 GO:0097718 disordered domain specific binding 2/184 28/18639 0.0714285714285714 7.23563664596273 0.0309681510160703 0.188416750392512 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 4/184 122/18639 0.0327868852459016 3.32127583749109 0.0328618163961095 0.196937178028628 GO:0005416 amino acid:monoatomic cation symporter activity 2/184 29/18639 0.0689655172413793 6.98613193403298 0.0330500108456349 0.196937178028628 GO:0005518 collagen binding 3/184 72/18639 0.0416666666666667 4.22078804347826 0.0343625146154984 0.202668708650593 GO:0048019 receptor antagonist activity 2/184 30/18639 0.0666666666666667 6.75326086956522 0.0351851357309447 0.205424327802889 GO:0061135 endopeptidase regulator activity 5/184 184/18639 0.0271739130434783 2.75268785444234 0.0360171445230985 0.207703652896007 GO:0015078 proton transmembrane transporter activity 5/184 185/18639 0.027027027027027 2.73780846063455 0.0367332649442274 0.207703652896007 GO:0048029 monosaccharide binding 3/184 74/18639 0.0405405405405405 4.10671269095182 0.0368251304768992 0.207703652896007 GO:0016878 acid-thiol ligase activity 2/184 31/18639 0.0645161290322581 6.53541374474053 0.0373722835660636 0.207703652896007 GO:0070325 lipoprotein particle receptor binding 2/184 31/18639 0.0645161290322581 6.53541374474053 0.0373722835660636 0.207703652896007 GO:0044183 protein folding chaperone 3/184 75/18639 0.04 4.05195652173913 0.0380895706996097 0.209674017755947 GO:0035591 signaling adaptor activity 4/184 129/18639 0.0310077519379845 3.14105156723964 0.039094930955792 0.211988089958699 GO:0098631 cell adhesion mediator activity 3/184 76/18639 0.0394736842105263 3.99864130434783 0.0393759869966233 0.211988089958699 GO:0031369 translation initiation factor binding 2/184 32/18639 0.0625 6.33118206521739 0.0396102313417639 0.211988089958699 GO:0016298 lipase activity 4/184 130/18639 0.0307692307692308 3.11688963210702 0.040036795500743 0.212305209169077 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 4/184 132/18639 0.0303030303030303 3.06966403162055 0.0419591438371787 0.220476228526266 GO:0016835 carbon-oxygen lyase activity 3/184 79/18639 0.0379746835443038 3.84679416620804 0.0433661644421966 0.225816604032339 GO:0002020 protease binding 4/184 136/18639 0.0294117647058824 2.97937979539642 0.0459582755170362 0.236355990123715 GO:0005154 epidermal growth factor receptor binding 2/184 35/18639 0.0571428571428571 5.78850931677019 0.0466169253877224 0.236355990123715 GO:0005343 organic acid:sodium symporter activity 2/184 35/18639 0.0571428571428571 5.78850931677019 0.0466169253877224 0.236355990123715 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 2/184 36/18639 0.0555555555555556 5.62771739130435 0.0490462159912571 0.242296690965356 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 2/184 36/18639 0.0555555555555556 5.62771739130435 0.0490462159912571 0.242296690965356 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 2/184 36/18639 0.0555555555555556 5.62771739130435 0.0490462159912571 0.242296690965356 GO:0003714 transcription corepressor activity 5/184 204/18639 0.0245098039215686 2.48281649616368 0.0520144949344906 0.254782865018098 GO:0019903 protein phosphatase binding 4/184 144/18639 0.0277777777777778 2.81385869565217 0.0545723450580874 0.262478180100434 GO:0019955 cytokine binding 4/184 144/18639 0.0277777777777778 2.81385869565217 0.0545723450580874 0.262478180100434 GO:0008081 phosphoric diester hydrolase activity 3/184 87/18639 0.0344827586206897 3.49306596701649 0.0549478543116825 0.262478180100434 GO:1901681 sulfur compound binding 6/184 275/18639 0.0218181818181818 2.2101581027668 0.0556265328284034 0.263542098154239 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 2/184 39/18639 0.0512820512820513 5.19481605351171 0.0565994263546373 0.265010250435703 GO:0015293 symporter activity 4/184 146/18639 0.0273972602739726 2.77531268612269 0.0568534101280747 0.265010250435703 GO:0015085 calcium ion transmembrane transporter activity 4/184 147/18639 0.0272108843537415 2.7564330079858 0.058012950594759 0.268251883550165 GO:0015036 disulfide oxidoreductase activity 2/184 40/18639 0.05 5.06494565217391 0.0592019549789287 0.271499906606777 GO:0030246 carbohydrate binding 6/184 280/18639 0.0214285714285714 2.17069099378882 0.0596548237700011 0.271499906606777 GO:0008509 monoatomic anion transmembrane transporter activity 4/184 149/18639 0.0268456375838926 2.71943390720747 0.0603699069604519 0.27260786111829 GO:0008137 NADH dehydrogenase (ubiquinone) activity 2/184 41/18639 0.0487804878048781 4.94141039236479 0.0618450951352686 0.274972807601425 GO:0016877 ligase activity, forming carbon-sulfur bonds 2/184 41/18639 0.0487804878048781 4.94141039236479 0.0618450951352686 0.274972807601425 GO:0016859 cis-trans isomerase activity 2/184 42/18639 0.0476190476190476 4.82375776397515 0.0645278013857868 0.284710451915914 GO:0004867 serine-type endopeptidase inhibitor activity 3/184 95/18639 0.0315789473684211 3.19891304347826 0.0678469477978186 0.297087392629842 GO:0003954 NADH dehydrogenase activity 2/184 44/18639 0.0454545454545455 4.60449604743083 0.0700078126070054 0.299737153235919 GO:0030020 extracellular matrix structural constituent conferring tensile strength 2/184 44/18639 0.0454545454545455 4.60449604743083 0.0700078126070054 0.299737153235919 GO:0030547 signaling receptor inhibitor activity 2/184 44/18639 0.0454545454545455 4.60449604743083 0.0700078126070054 0.299737153235919 GO:0140303 intramembrane lipid transporter activity 2/184 45/18639 0.0444444444444444 4.50217391304348 0.0728031082320502 0.309413209986213 GO:0004866 endopeptidase inhibitor activity 4/184 161/18639 0.0248447204968944 2.51674318120443 0.0755575326306406 0.316785678101046 GO:0030291 protein serine/threonine kinase inhibitor activity 2/184 46/18639 0.0434782608695652 4.40430056710775 0.0756339508268934 0.316785678101046 GO:0015103 inorganic anion transmembrane transporter activity 4/184 165/18639 0.0242424242424242 2.45573122529644 0.0810104610275206 0.336059238636181 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 2/184 48/18639 0.0416666666666667 4.22078804347826 0.0813984315035734 0.336059238636181 GO:0016874 ligase activity 4/184 167/18639 0.0239520958083832 2.42632127050247 0.0838083618681668 0.33914484710131 GO:0060590 ATPase regulator activity 2/184 49/18639 0.0408163265306122 4.1346495119787 0.0843301851814021 0.33914484710131 GO:0016830 carbon-carbon lyase activity 2/184 51/18639 0.0392156862745098 3.97250639386189 0.0902881209683702 0.33914484710131 GO:0008201 heparin binding 4/184 172/18639 0.0232558139534884 2.35578867542973 0.0910078562311716 0.33914484710131 GO:0005539 glycosaminoglycan binding 5/184 242/18639 0.0206611570247934 2.0929527488322 0.0921767752273688 0.33914484710131 GO:0005080 protein kinase C binding 2/184 52/18639 0.0384615384615385 3.89611204013378 0.0933125080338687 0.33914484710131 GO:0030159 signaling receptor complex adaptor activity 2/184 52/18639 0.0384615384615385 3.89611204013378 0.0933125080338687 0.33914484710131 GO:0003823 antigen binding 4/184 174/18639 0.0229885057471264 2.32871064467766 0.0939682873050596 0.33914484710131 GO:0004862 cAMP-dependent protein kinase inhibitor activity 1/184 10/18639 0.1 10.1298913043478 0.0944676823240673 0.33914484710131 GO:0004955 prostaglandin receptor activity 1/184 10/18639 0.1 10.1298913043478 0.0944676823240673 0.33914484710131 GO:0008190 eukaryotic initiation factor 4E binding 1/184 10/18639 0.1 10.1298913043478 0.0944676823240673 0.33914484710131 GO:0015187 glycine transmembrane transporter activity 1/184 10/18639 0.1 10.1298913043478 0.0944676823240673 0.33914484710131 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines 1/184 10/18639 0.1 10.1298913043478 0.0944676823240673 0.33914484710131 GO:0019531 oxalate transmembrane transporter activity 1/184 10/18639 0.1 10.1298913043478 0.0944676823240673 0.33914484710131 GO:0031957 very long-chain fatty acid-CoA ligase activity 1/184 10/18639 0.1 10.1298913043478 0.0944676823240673 0.33914484710131 GO:0032395 MHC class II receptor activity 1/184 10/18639 0.1 10.1298913043478 0.0944676823240673 0.33914484710131 GO:0035374 chondroitin sulfate binding 1/184 10/18639 0.1 10.1298913043478 0.0944676823240673 0.33914484710131 GO:0043295 glutathione binding 1/184 10/18639 0.1 10.1298913043478 0.0944676823240673 0.33914484710131 GO:0070739 protein-glutamic acid ligase activity 1/184 10/18639 0.1 10.1298913043478 0.0944676823240673 0.33914484710131 GO:0070740 tubulin-glutamic acid ligase activity 1/184 10/18639 0.1 10.1298913043478 0.0944676823240673 0.33914484710131 GO:0072582 17-beta-hydroxysteroid dehydrogenase (NADP+) activity 1/184 10/18639 0.1 10.1298913043478 0.0944676823240673 0.33914484710131 GO:0051018 protein kinase A binding 2/184 53/18639 0.0377358490566038 3.82260049220673 0.0963660019737676 0.343516998114475 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 2/184 54/18639 0.037037037037037 3.7518115942029 0.0994477411559733 0.343516998114475 GO:0051287 NAD binding 2/184 54/18639 0.037037037037037 3.7518115942029 0.0994477411559733 0.343516998114475 GO:0098632 cell-cell adhesion mediator activity 2/184 55/18639 0.0363636363636364 3.68359683794466 0.102556877955469 0.343516998114475 GO:0003953 NAD+ nucleosidase activity 1/184 11/18639 0.0909090909090909 9.20899209486166 0.103411691473908 0.343516998114475 GO:0004016 adenylate cyclase activity 1/184 11/18639 0.0909090909090909 9.20899209486166 0.103411691473908 0.343516998114475 GO:0004954 prostanoid receptor activity 1/184 11/18639 0.0909090909090909 9.20899209486166 0.103411691473908 0.343516998114475 GO:0042608 T cell receptor binding 1/184 11/18639 0.0909090909090909 9.20899209486166 0.103411691473908 0.343516998114475 GO:0047676 arachidonate-CoA ligase activity 1/184 11/18639 0.0909090909090909 9.20899209486166 0.103411691473908 0.343516998114475 GO:0050786 RAGE receptor binding 1/184 11/18639 0.0909090909090909 9.20899209486166 0.103411691473908 0.343516998114475 GO:0097493 structural molecule activity conferring elasticity 1/184 11/18639 0.0909090909090909 9.20899209486166 0.103411691473908 0.343516998114475 GO:0140031 phosphorylation-dependent protein binding 1/184 11/18639 0.0909090909090909 9.20899209486166 0.103411691473908 0.343516998114475 GO:1900750 oligopeptide binding 1/184 11/18639 0.0909090909090909 9.20899209486166 0.103411691473908 0.343516998114475 GO:0035401 histone H3Y41 kinase activity 3/184 115/18639 0.0260869565217391 2.64258034026465 0.105330969571932 0.345916479616915 GO:0140801 histone H2AXY142 kinase activity 3/184 115/18639 0.0260869565217391 2.64258034026465 0.105330969571932 0.345916479616915 GO:0019887 protein kinase regulator activity 5/184 255/18639 0.0196078431372549 1.98625319693095 0.108761139190617 0.347009673007016 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 2/184 58/18639 0.0344827586206897 3.49306596701649 0.112040403938862 0.347009673007016 GO:0004300 enoyl-CoA hydratase activity 1/184 12/18639 0.0833333333333333 8.44157608695652 0.112267835384623 0.347009673007016 GO:0005078 MAP-kinase scaffold activity 1/184 12/18639 0.0833333333333333 8.44157608695652 0.112267835384623 0.347009673007016 GO:0005436 sodium:phosphate symporter activity 1/184 12/18639 0.0833333333333333 8.44157608695652 0.112267835384623 0.347009673007016 GO:0008179 adenylate cyclase binding 1/184 12/18639 0.0833333333333333 8.44157608695652 0.112267835384623 0.347009673007016 GO:0008603 cAMP-dependent protein kinase regulator activity 1/184 12/18639 0.0833333333333333 8.44157608695652 0.112267835384623 0.347009673007016 GO:0015269 calcium-activated potassium channel activity 1/184 12/18639 0.0833333333333333 8.44157608695652 0.112267835384623 0.347009673007016 GO:0016208 AMP binding 1/184 12/18639 0.0833333333333333 8.44157608695652 0.112267835384623 0.347009673007016 GO:0042301 phosphate ion binding 1/184 12/18639 0.0833333333333333 8.44157608695652 0.112267835384623 0.347009673007016 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 1/184 12/18639 0.0833333333333333 8.44157608695652 0.112267835384623 0.347009673007016 GO:0019902 phosphatase binding 4/184 190/18639 0.0210526315789474 2.13260869565217 0.119236758587051 0.355123706312241 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 1/184 13/18639 0.0769230769230769 7.79222408026756 0.121036972566629 0.355123706312241 GO:0005172 vascular endothelial growth factor receptor binding 1/184 13/18639 0.0769230769230769 7.79222408026756 0.121036972566629 0.355123706312241 GO:0008035 high-density lipoprotein particle binding 1/184 13/18639 0.0769230769230769 7.79222408026756 0.121036972566629 0.355123706312241 GO:0035325 Toll-like receptor binding 1/184 13/18639 0.0769230769230769 7.79222408026756 0.121036972566629 0.355123706312241 GO:0043560 insulin receptor substrate binding 1/184 13/18639 0.0769230769230769 7.79222408026756 0.121036972566629 0.355123706312241 GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity 1/184 13/18639 0.0769230769230769 7.79222408026756 0.121036972566629 0.355123706312241 GO:0070700 BMP receptor binding 1/184 13/18639 0.0769230769230769 7.79222408026756 0.121036972566629 0.355123706312241 GO:0140333 glycerophospholipid flippase activity 1/184 13/18639 0.0769230769230769 7.79222408026756 0.121036972566629 0.355123706312241 GO:0140666 annealing activity 1/184 13/18639 0.0769230769230769 7.79222408026756 0.121036972566629 0.355123706312241 GO:0019905 syntaxin binding 2/184 61/18639 0.0327868852459016 3.32127583749109 0.121741299202205 0.355386216863001 GO:0005313 L-glutamate transmembrane transporter activity 1/184 14/18639 0.0714285714285714 7.23563664596273 0.129719953187682 0.361141297108328 GO:0008195 phosphatidate phosphatase activity 1/184 14/18639 0.0714285714285714 7.23563664596273 0.129719953187682 0.361141297108328 GO:0008559 ABC-type xenobiotic transporter activity 1/184 14/18639 0.0714285714285714 7.23563664596273 0.129719953187682 0.361141297108328 GO:0016530 metallochaperone activity 1/184 14/18639 0.0714285714285714 7.23563664596273 0.129719953187682 0.361141297108328 GO:0030283 testosterone dehydrogenase [NAD(P)+] activity 1/184 14/18639 0.0714285714285714 7.23563664596273 0.129719953187682 0.361141297108328 GO:0034236 protein kinase A catalytic subunit binding 1/184 14/18639 0.0714285714285714 7.23563664596273 0.129719953187682 0.361141297108328 GO:0043176 amine binding 1/184 14/18639 0.0714285714285714 7.23563664596273 0.129719953187682 0.361141297108328 GO:0044548 S100 protein binding 1/184 14/18639 0.0714285714285714 7.23563664596273 0.129719953187682 0.361141297108328 GO:1901612 cardiolipin binding 1/184 14/18639 0.0714285714285714 7.23563664596273 0.129719953187682 0.361141297108328 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 3/184 128/18639 0.0234375 2.37419327445652 0.133174891708172 0.361141297108328 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 3/184 130/18639 0.0230769230769231 2.33766722408027 0.137667916646294 0.361141297108328 GO:0004467 long-chain fatty acid-CoA ligase activity 1/184 15/18639 0.0666666666666667 6.75326086956522 0.138317619153506 0.361141297108328 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 1/184 15/18639 0.0666666666666667 6.75326086956522 0.138317619153506 0.361141297108328 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 1/184 15/18639 0.0666666666666667 6.75326086956522 0.138317619153506 0.361141297108328 GO:0004953 icosanoid receptor activity 1/184 15/18639 0.0666666666666667 6.75326086956522 0.138317619153506 0.361141297108328 GO:0010181 FMN binding 1/184 15/18639 0.0666666666666667 6.75326086956522 0.138317619153506 0.361141297108328 GO:0016846 carbon-sulfur lyase activity 1/184 15/18639 0.0666666666666667 6.75326086956522 0.138317619153506 0.361141297108328 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 1/184 15/18639 0.0666666666666667 6.75326086956522 0.138317619153506 0.361141297108328 GO:0031386 protein tag activity 1/184 15/18639 0.0666666666666667 6.75326086956522 0.138317619153506 0.361141297108328 GO:0055105 ubiquitin-protein transferase inhibitor activity 1/184 15/18639 0.0666666666666667 6.75326086956522 0.138317619153506 0.361141297108328 GO:0140776 protein-containing complex destabilizing activity 1/184 15/18639 0.0666666666666667 6.75326086956522 0.138317619153506 0.361141297108328 GO:0141047 molecular tag activity 1/184 15/18639 0.0666666666666667 6.75326086956522 0.138317619153506 0.361141297108328 GO:0005262 calcium channel activity 3/184 131/18639 0.0229007633587786 2.31982243611019 0.139933769392368 0.361141297108328 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 2/184 67/18639 0.0298507462686567 3.02384815055159 0.141713306212286 0.361141297108328 GO:0050840 extracellular matrix binding 2/184 67/18639 0.0298507462686567 3.02384815055159 0.141713306212286 0.361141297108328 GO:0005179 hormone activity 3/184 132/18639 0.0227272727272727 2.30224802371542 0.142212249056442 0.361141297108328 GO:0005548 phospholipid transporter activity 2/184 68/18639 0.0294117647058824 2.97937979539642 0.145107515537803 0.361141297108328 GO:0030145 manganese ion binding 2/184 68/18639 0.0294117647058824 2.97937979539642 0.145107515537803 0.361141297108328 GO:0000062 fatty-acyl-CoA binding 1/184 16/18639 0.0625 6.33118206521739 0.146830804187642 0.361141297108328 GO:0003688 DNA replication origin binding 1/184 16/18639 0.0625 6.33118206521739 0.146830804187642 0.361141297108328 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 1/184 16/18639 0.0625 6.33118206521739 0.146830804187642 0.361141297108328 GO:0005159 insulin-like growth factor receptor binding 1/184 16/18639 0.0625 6.33118206521739 0.146830804187642 0.361141297108328 GO:0005324 long-chain fatty acid transmembrane transporter activity 1/184 16/18639 0.0625 6.33118206521739 0.146830804187642 0.361141297108328 GO:0015562 efflux transmembrane transporter activity 1/184 16/18639 0.0625 6.33118206521739 0.146830804187642 0.361141297108328 GO:0061809 NAD+ nucleosidase activity, cyclic ADP-ribose generating 1/184 16/18639 0.0625 6.33118206521739 0.146830804187642 0.361141297108328 GO:0140327 flippase activity 1/184 16/18639 0.0625 6.33118206521739 0.146830804187642 0.361141297108328 GO:0140328 floppase activity 1/184 16/18639 0.0625 6.33118206521739 0.146830804187642 0.361141297108328 GO:0002039 p53 binding 2/184 69/18639 0.0289855072463768 2.93620037807183 0.148518624207083 0.362317475021173 GO:0005516 calmodulin binding 4/184 207/18639 0.0193236714975845 1.95746691871456 0.148924581230365 0.362317475021173 GO:0097110 scaffold protein binding 2/184 70/18639 0.0285714285714286 2.89425465838509 0.151945973163765 0.362317475021173 GO:0016922 nuclear receptor binding 3/184 137/18639 0.0218978102189781 2.21822437321485 0.153787056810594 0.362317475021173 GO:0019207 kinase regulator activity 5/184 287/18639 0.0174216027874564 1.76478942584457 0.155162976726672 0.362317475021173 GO:0005092 GDP-dissociation inhibitor activity 1/184 17/18639 0.0588235294117647 5.95875959079284 0.155260333910537 0.362317475021173 GO:0015278 intracellularly gated calcium channel activity 1/184 17/18639 0.0588235294117647 5.95875959079284 0.155260333910537 0.362317475021173 GO:0016018 cyclosporin A binding 1/184 17/18639 0.0588235294117647 5.95875959079284 0.155260333910537 0.362317475021173 GO:0036041 long-chain fatty acid binding 1/184 17/18639 0.0588235294117647 5.95875959079284 0.155260333910537 0.362317475021173 GO:0051787 misfolded protein binding 1/184 17/18639 0.0588235294117647 5.95875959079284 0.155260333910537 0.362317475021173 GO:0070403 NAD+ binding 1/184 17/18639 0.0588235294117647 5.95875959079284 0.155260333910537 0.362317475021173 GO:1901567 fatty acid derivative binding 1/184 17/18639 0.0588235294117647 5.95875959079284 0.155260333910537 0.362317475021173 GO:0030295 protein kinase activator activity 3/184 139/18639 0.0215827338129496 2.18630747575852 0.158498380055029 0.362317475021173 GO:0070851 growth factor receptor binding 3/184 139/18639 0.0215827338129496 2.18630747575852 0.158498380055029 0.362317475021173 GO:0043539 protein serine/threonine kinase activator activity 2/184 73/18639 0.0273972602739726 2.77531268612269 0.162319038770089 0.362317475021173 GO:0003746 translation elongation factor activity 1/184 18/18639 0.0555555555555556 5.62771739130435 0.163607025917865 0.362317475021173 GO:0008525 phosphatidylcholine transporter activity 1/184 18/18639 0.0555555555555556 5.62771739130435 0.163607025917865 0.362317475021173 GO:0015172 acidic amino acid transmembrane transporter activity 1/184 18/18639 0.0555555555555556 5.62771739130435 0.163607025917865 0.362317475021173 GO:0017075 syntaxin-1 binding 1/184 18/18639 0.0555555555555556 5.62771739130435 0.163607025917865 0.362317475021173 GO:0017128 phospholipid scramblase activity 1/184 18/18639 0.0555555555555556 5.62771739130435 0.163607025917865 0.362317475021173 GO:0034185 apolipoprotein binding 1/184 18/18639 0.0555555555555556 5.62771739130435 0.163607025917865 0.362317475021173 GO:0035615 clathrin adaptor activity 1/184 18/18639 0.0555555555555556 5.62771739130435 0.163607025917865 0.362317475021173 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 1/184 18/18639 0.0555555555555556 5.62771739130435 0.163607025917865 0.362317475021173 GO:0050811 GABA receptor binding 1/184 18/18639 0.0555555555555556 5.62771739130435 0.163607025917865 0.362317475021173 GO:1901611 phosphatidylglycerol binding 1/184 18/18639 0.0555555555555556 5.62771739130435 0.163607025917865 0.362317475021173 GO:1990381 ubiquitin-specific protease binding 1/184 18/18639 0.0555555555555556 5.62771739130435 0.163607025917865 0.362317475021173 GO:0003725 double-stranded RNA binding 2/184 75/18639 0.0266666666666667 2.70130434782609 0.169304032995 0.365227340948462 GO:0003756 protein disulfide isomerase activity 1/184 19/18639 0.0526315789473684 5.33152173913043 0.1718716898581 0.365227340948462 GO:0004303 estradiol 17-beta-dehydrogenase [NAD(P)+] activity 1/184 19/18639 0.0526315789473684 5.33152173913043 0.1718716898581 0.365227340948462 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 1/184 19/18639 0.0526315789473684 5.33152173913043 0.1718716898581 0.365227340948462 GO:0015245 fatty acid transmembrane transporter activity 1/184 19/18639 0.0526315789473684 5.33152173913043 0.1718716898581 0.365227340948462 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 1/184 19/18639 0.0526315789473684 5.33152173913043 0.1718716898581 0.365227340948462 GO:0031420 alkali metal ion binding 1/184 19/18639 0.0526315789473684 5.33152173913043 0.1718716898581 0.365227340948462 GO:0034987 immunoglobulin receptor binding 1/184 19/18639 0.0526315789473684 5.33152173913043 0.1718716898581 0.365227340948462 GO:0042577 lipid phosphatase activity 1/184 19/18639 0.0526315789473684 5.33152173913043 0.1718716898581 0.365227340948462 GO:0046624 sphingolipid transporter activity 1/184 19/18639 0.0526315789473684 5.33152173913043 0.1718716898581 0.365227340948462 GO:0120227 acyl-CoA binding 1/184 19/18639 0.0526315789473684 5.33152173913043 0.1718716898581 0.365227340948462 GO:0004745 all-trans-retinol dehydrogenase (NAD+) activity 1/184 20/18639 0.05 5.06494565217391 0.180055127509341 0.37742268952643 GO:0015095 magnesium ion transmembrane transporter activity 1/184 20/18639 0.05 5.06494565217391 0.180055127509341 0.37742268952643 GO:0043024 ribosomal small subunit binding 1/184 20/18639 0.05 5.06494565217391 0.180055127509341 0.37742268952643 GO:0019209 kinase activator activity 3/184 148/18639 0.0202702702702703 2.05335634547591 0.180222599151029 0.37742268952643 GO:0048306 calcium-dependent protein binding 2/184 80/18639 0.025 2.53247282608696 0.186975521432544 0.384294702439653 GO:0001846 opsonin binding 1/184 21/18639 0.0476190476190476 4.82375776397515 0.188158132855401 0.384294702439653 GO:0005123 death receptor binding 1/184 21/18639 0.0476190476190476 4.82375776397515 0.188158132855401 0.384294702439653 GO:0009931 calcium-dependent protein serine/threonine kinase activity 1/184 21/18639 0.0476190476190476 4.82375776397515 0.188158132855401 0.384294702439653 GO:0009975 cyclase activity 1/184 21/18639 0.0476190476190476 4.82375776397515 0.188158132855401 0.384294702439653 GO:0035613 RNA stem-loop binding 1/184 21/18639 0.0476190476190476 4.82375776397515 0.188158132855401 0.384294702439653 GO:0140312 cargo adaptor activity 1/184 21/18639 0.0476190476190476 4.82375776397515 0.188158132855401 0.384294702439653 GO:0008093 cytoskeletal anchor activity 1/184 22/18639 0.0454545454545455 4.60449604743083 0.196181492161159 0.395097221146864 GO:0016881 acid-amino acid ligase activity 1/184 22/18639 0.0454545454545455 4.60449604743083 0.196181492161159 0.395097221146864 GO:0061133 endopeptidase activator activity 1/184 22/18639 0.0454545454545455 4.60449604743083 0.196181492161159 0.395097221146864 GO:0140035 ubiquitin-like protein reader activity 1/184 22/18639 0.0454545454545455 4.60449604743083 0.196181492161159 0.395097221146864 GO:0008135 translation factor activity, RNA binding 2/184 83/18639 0.0240963855421687 2.44093766369827 0.197699286593895 0.396771484900248 GO:0140375 immune receptor activity 3/184 156/18639 0.0192307692307692 1.94805602006689 0.200167636801241 0.397255282085115 GO:0004860 protein kinase inhibitor activity 2/184 84/18639 0.0238095238095238 2.41187888198758 0.201290814845394 0.397255282085115 GO:0180051 translation factor activity 2/184 84/18639 0.0238095238095238 2.41187888198758 0.201290814845394 0.397255282085115 GO:0004022 alcohol dehydrogenase (NAD+) activity 1/184 23/18639 0.0434782608695652 4.40430056710775 0.204125984047196 0.397255282085115 GO:0008171 O-methyltransferase activity 1/184 23/18639 0.0434782608695652 4.40430056710775 0.204125984047196 0.397255282085115 GO:0016849 phosphorus-oxygen lyase activity 1/184 23/18639 0.0434782608695652 4.40430056710775 0.204125984047196 0.397255282085115 GO:0017134 fibroblast growth factor binding 1/184 23/18639 0.0434782608695652 4.40430056710775 0.204125984047196 0.397255282085115 GO:0043274 phospholipase binding 1/184 23/18639 0.0434782608695652 4.40430056710775 0.204125984047196 0.397255282085115 GO:0070577 lysine-acetylated histone binding 1/184 23/18639 0.0434782608695652 4.40430056710775 0.204125984047196 0.397255282085115 GO:0015079 potassium ion transmembrane transporter activity 3/184 160/18639 0.01875 1.89935461956522 0.21033190327061 0.399125717875637 GO:0005315 phosphate transmembrane transporter activity 1/184 24/18639 0.0416666666666667 4.22078804347826 0.211992379563704 0.399125717875637 GO:0005540 hyaluronic acid binding 1/184 24/18639 0.0416666666666667 4.22078804347826 0.211992379563704 0.399125717875637 GO:0042625 ATPase-coupled ion transmembrane transporter activity 1/184 24/18639 0.0416666666666667 4.22078804347826 0.211992379563704 0.399125717875637 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 1/184 24/18639 0.0416666666666667 4.22078804347826 0.211992379563704 0.399125717875637 GO:0046961 proton-transporting ATPase activity, rotational mechanism 1/184 24/18639 0.0416666666666667 4.22078804347826 0.211992379563704 0.399125717875637 GO:0048027 mRNA 5'-UTR binding 1/184 24/18639 0.0416666666666667 4.22078804347826 0.211992379563704 0.399125717875637 GO:0050431 transforming growth factor beta binding 1/184 24/18639 0.0416666666666667 4.22078804347826 0.211992379563704 0.399125717875637 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 1/184 24/18639 0.0416666666666667 4.22078804347826 0.211992379563704 0.399125717875637 GO:0140033 acetylation-dependent protein binding 1/184 24/18639 0.0416666666666667 4.22078804347826 0.211992379563704 0.399125717875637 GO:0004197 cysteine-type endopeptidase activity 2/184 88/18639 0.0227272727272727 2.30224802371542 0.21572819176453 0.403530404012617 GO:0016651 oxidoreductase activity, acting on NAD(P)H 2/184 88/18639 0.0227272727272727 2.30224802371542 0.21572819176453 0.403530404012617 GO:0003712 transcription coregulator activity 7/184 495/18639 0.0141414141414141 1.43250988142293 0.218443042395846 0.407094397966654 GO:0001848 complement binding 1/184 25/18639 0.04 4.05195652173913 0.219781442263692 0.407094397966654 GO:0004709 MAP kinase kinase kinase activity 1/184 25/18639 0.04 4.05195652173913 0.219781442263692 0.407094397966654 GO:0019210 kinase inhibitor activity 2/184 90/18639 0.0222222222222222 2.25108695652174 0.222982898871813 0.407094397966654 GO:0072341 modified amino acid binding 2/184 91/18639 0.021978021978022 2.2263497372193 0.226617632997165 0.407094397966654 GO:0004435 phosphatidylinositol phospholipase C activity 1/184 26/18639 0.0384615384615385 3.89611204013378 0.227493928275483 0.407094397966654 GO:0005112 Notch binding 1/184 26/18639 0.0384615384615385 3.89611204013378 0.227493928275483 0.407094397966654 GO:0005227 calcium-activated cation channel activity 1/184 26/18639 0.0384615384615385 3.89611204013378 0.227493928275483 0.407094397966654 GO:0008143 poly(A) binding 1/184 26/18639 0.0384615384615385 3.89611204013378 0.227493928275483 0.407094397966654 GO:0030247 polysaccharide binding 1/184 26/18639 0.0384615384615385 3.89611204013378 0.227493928275483 0.407094397966654 GO:0034237 protein kinase A regulatory subunit binding 1/184 26/18639 0.0384615384615385 3.89611204013378 0.227493928275483 0.407094397966654 GO:0050681 nuclear androgen receptor binding 1/184 26/18639 0.0384615384615385 3.89611204013378 0.227493928275483 0.407094397966654 GO:0070006 metalloaminopeptidase activity 1/184 26/18639 0.0384615384615385 3.89611204013378 0.227493928275483 0.407094397966654 GO:0097602 cullin family protein binding 1/184 26/18639 0.0384615384615385 3.89611204013378 0.227493928275483 0.407094397966654 GO:0015252 proton channel activity 1/184 27/18639 0.037037037037037 3.7518115942029 0.235130586374517 0.415613085395935 GO:0023026 MHC class II protein complex binding 1/184 27/18639 0.037037037037037 3.7518115942029 0.235130586374517 0.415613085395935 GO:0035255 ionotropic glutamate receptor binding 1/184 27/18639 0.037037037037037 3.7518115942029 0.235130586374517 0.415613085395935 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 1/184 27/18639 0.037037037037037 3.7518115942029 0.235130586374517 0.415613085395935 GO:0140030 modification-dependent protein binding 3/184 173/18639 0.0173410404624277 1.75662854988691 0.244078300967328 0.430113591338767 GO:0004896 cytokine receptor activity 2/184 96/18639 0.0208333333333333 2.11039402173913 0.244847553144394 0.430157707347903 GO:0005261 monoatomic cation channel activity 5/184 341/18639 0.0146627565982405 1.48532130562285 0.247874691873669 0.43415627849388 GO:0043236 laminin binding 1/184 29/18639 0.0344827586206897 3.49306596701649 0.250179377597631 0.43555325376937 GO:0099604 ligand-gated calcium channel activity 1/184 29/18639 0.0344827586206897 3.49306596701649 0.250179377597631 0.43555325376937 GO:0005319 lipid transporter activity 3/184 178/18639 0.0168539325842697 1.70728505129458 0.257289234128278 0.440499224555238 GO:0001968 fibronectin binding 1/184 30/18639 0.0333333333333333 3.37663043478261 0.257592972144758 0.440499224555238 GO:0005217 intracellularly ligand-gated monoatomic ion channel activity 1/184 30/18639 0.0333333333333333 3.37663043478261 0.257592972144758 0.440499224555238 GO:0008106 alcohol dehydrogenase (NADP+) activity 1/184 30/18639 0.0333333333333333 3.37663043478261 0.257592972144758 0.440499224555238 GO:0022839 monoatomic ion-gated channel activity 1/184 30/18639 0.0333333333333333 3.37663043478261 0.257592972144758 0.440499224555238 GO:0033612 receptor serine/threonine kinase binding 1/184 30/18639 0.0333333333333333 3.37663043478261 0.257592972144758 0.440499224555238 GO:0005310 dicarboxylic acid transmembrane transporter activity 1/184 31/18639 0.032258064516129 3.26770687237027 0.264933661764049 0.445702119553349 GO:0005452 solute:inorganic anion antiporter activity 1/184 31/18639 0.032258064516129 3.26770687237027 0.264933661764049 0.445702119553349 GO:0017147 Wnt-protein binding 1/184 31/18639 0.032258064516129 3.26770687237027 0.264933661764049 0.445702119553349 GO:0047499 calcium-independent phospholipase A2 activity 1/184 31/18639 0.032258064516129 3.26770687237027 0.264933661764049 0.445702119553349 GO:0072349 modified amino acid transmembrane transporter activity 1/184 31/18639 0.032258064516129 3.26770687237027 0.264933661764049 0.445702119553349 GO:0008238 exopeptidase activity 2/184 102/18639 0.0196078431372549 1.98625319693095 0.266792944636554 0.445702119553349 GO:0005253 monoatomic anion channel activity 2/184 103/18639 0.0194174757281553 1.96696918531026 0.270452471196592 0.445702119553349 GO:0015106 bicarbonate transmembrane transporter activity 1/184 32/18639 0.03125 3.1655910326087 0.272202159519606 0.445702119553349 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/184 32/18639 0.03125 3.1655910326087 0.272202159519606 0.445702119553349 GO:0042910 xenobiotic transmembrane transporter activity 1/184 32/18639 0.03125 3.1655910326087 0.272202159519606 0.445702119553349 GO:0043425 bHLH transcription factor binding 1/184 32/18639 0.03125 3.1655910326087 0.272202159519606 0.445702119553349 GO:0047498 calcium-dependent phospholipase A2 activity 1/184 32/18639 0.03125 3.1655910326087 0.272202159519606 0.445702119553349 GO:0070717 poly-purine tract binding 1/184 32/18639 0.03125 3.1655910326087 0.272202159519606 0.445702119553349 GO:0071813 lipoprotein particle binding 1/184 32/18639 0.03125 3.1655910326087 0.272202159519606 0.445702119553349 GO:0071814 protein-lipid complex binding 1/184 32/18639 0.03125 3.1655910326087 0.272202159519606 0.445702119553349 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 1/184 33/18639 0.0303030303030303 3.06966403162055 0.279399171539189 0.450555961703874 GO:0019956 chemokine binding 1/184 33/18639 0.0303030303030303 3.06966403162055 0.279399171539189 0.450555961703874 GO:0030296 protein tyrosine kinase activator activity 1/184 33/18639 0.0303030303030303 3.06966403162055 0.279399171539189 0.450555961703874 GO:0071889 14-3-3 protein binding 1/184 33/18639 0.0303030303030303 3.06966403162055 0.279399171539189 0.450555961703874 GO:0140416 transcription regulator inhibitor activity 1/184 33/18639 0.0303030303030303 3.06966403162055 0.279399171539189 0.450555961703874 GO:0008234 cysteine-type peptidase activity 3/184 187/18639 0.0160427807486631 1.62511625203441 0.281297165474001 0.450555961703874 GO:0000149 SNARE binding 2/184 106/18639 0.0188679245283019 1.91130024610336 0.281427231748028 0.450555961703874 GO:0008013 beta-catenin binding 2/184 106/18639 0.0188679245283019 1.91130024610336 0.281427231748028 0.450555961703874 GO:0005216 monoatomic ion channel activity 6/184 448/18639 0.0133928571428571 1.35668187111801 0.282182107503118 0.450555961703874 GO:0008376 acetylgalactosaminyltransferase activity 1/184 34/18639 0.0294117647058824 2.97937979539642 0.286525397081315 0.45373062880274 GO:0015035 protein-disulfide reductase activity 1/184 34/18639 0.0294117647058824 2.97937979539642 0.286525397081315 0.45373062880274 GO:0016831 carboxy-lyase activity 1/184 34/18639 0.0294117647058824 2.97937979539642 0.286525397081315 0.45373062880274 GO:0042578 phosphoric ester hydrolase activity 5/184 363/18639 0.0137741046831956 1.3953018325548 0.289189137469092 0.456697599609658 GO:0004623 phospholipase A2 activity 1/184 35/18639 0.0285714285714286 2.89425465838509 0.293581528601715 0.458621955491328 GO:0016229 steroid dehydrogenase activity 1/184 35/18639 0.0285714285714286 2.89425465838509 0.293581528601715 0.458621955491328 GO:0043015 gamma-tubulin binding 1/184 35/18639 0.0285714285714286 2.89425465838509 0.293581528601715 0.458621955491328 GO:0061631 ubiquitin conjugating enzyme activity 1/184 35/18639 0.0285714285714286 2.89425465838509 0.293581528601715 0.458621955491328 GO:0004033 aldo-keto reductase (NADPH) activity 1/184 36/18639 0.0277777777777778 2.81385869565217 0.300568251819157 0.463275865470593 GO:0004869 cysteine-type endopeptidase inhibitor activity 1/184 36/18639 0.0277777777777778 2.81385869565217 0.300568251819157 0.463275865470593 GO:0005484 SNAP receptor activity 1/184 36/18639 0.0277777777777778 2.81385869565217 0.300568251819157 0.463275865470593 GO:0044390 ubiquitin-like protein conjugating enzyme binding 1/184 36/18639 0.0277777777777778 2.81385869565217 0.300568251819157 0.463275865470593 GO:0055106 ubiquitin-protein transferase regulator activity 1/184 36/18639 0.0277777777777778 2.81385869565217 0.300568251819157 0.463275865470593 GO:0023023 MHC protein complex binding 1/184 37/18639 0.027027027027027 2.73780846063455 0.307486245780629 0.472678324630861 GO:0005109 frizzled binding 1/184 38/18639 0.0263157894736842 2.66576086956522 0.314336182925902 0.481926561621144 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 1/184 39/18639 0.0256410256410256 2.59740802675585 0.321118729151461 0.490300143541011 GO:1990782 protein tyrosine kinase binding 2/184 117/18639 0.0170940170940171 1.73160535117057 0.321494384778622 0.490300143541011 GO:0004177 aminopeptidase activity 1/184 40/18639 0.025 2.53247282608696 0.327834543873834 0.496042843871927 GO:0030331 nuclear estrogen receptor binding 1/184 40/18639 0.025 2.53247282608696 0.327834543873834 0.496042843871927 GO:0071949 FAD binding 1/184 40/18639 0.025 2.53247282608696 0.327834543873834 0.496042843871927 GO:0001530 lipopolysaccharide binding 1/184 41/18639 0.024390243902439 2.4707051961824 0.334484280092298 0.502160815307398 GO:0017080 sodium channel regulator activity 1/184 41/18639 0.024390243902439 2.4707051961824 0.334484280092298 0.502160815307398 GO:0061650 ubiquitin-like protein conjugating enzyme activity 1/184 41/18639 0.024390243902439 2.4707051961824 0.334484280092298 0.502160815307398 GO:0015108 chloride transmembrane transporter activity 2/184 121/18639 0.0165289256198347 1.67436219906576 0.335943694132154 0.503045220747111 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 2/184 122/18639 0.0163934426229508 1.66063791874555 0.339542428338086 0.507120215967477 GO:0035198 miRNA binding 1/184 42/18639 0.0238095238095238 2.41187888198758 0.341068584450994 0.508086705702769 GO:0005267 potassium channel activity 2/184 124/18639 0.0161290322580645 1.63385343618513 0.346721897642849 0.515143385229872 GO:0005245 voltage-gated calcium channel activity 1/184 43/18639 0.0232558139534884 2.35578867542973 0.347588097300433 0.515143385229872 GO:0051539 4 iron, 4 sulfur cluster binding 1/184 45/18639 0.0222222222222222 2.25108695652174 0.360435278770382 0.532817368617087 GO:0030276 clathrin binding 1/184 46/18639 0.0217391304347826 2.20215028355388 0.366764197169126 0.540790066234069 GO:0016798 hydrolase activity, acting on glycosyl bonds 2/184 130/18639 0.0153846153846154 1.55844481605351 0.368100161025887 0.541378862781075 GO:0031072 heat shock protein binding 2/184 131/18639 0.0152671755725191 1.54654829074013 0.371637624462065 0.541738231452909 GO:0001784 phosphotyrosine residue binding 1/184 47/18639 0.0212765957446809 2.15529602220167 0.37303082373401 0.541738231452909 GO:0005504 fatty acid binding 1/184 47/18639 0.0212765957446809 2.15529602220167 0.37303082373401 0.541738231452909 GO:0043495 protein-membrane adaptor activity 1/184 47/18639 0.0212765957446809 2.15529602220167 0.37303082373401 0.541738231452909 GO:0140359 ABC-type transporter activity 1/184 47/18639 0.0212765957446809 2.15529602220167 0.37303082373401 0.541738231452909 GO:0016879 ligase activity, forming carbon-nitrogen bonds 1/184 48/18639 0.0208333333333333 2.11039402173913 0.379235768249551 0.549369107890328 GO:0051087 protein-folding chaperone binding 2/184 134/18639 0.0149253731343284 1.51192407527579 0.382202206679685 0.552282188652145 GO:0022836 gated channel activity 4/184 318/18639 0.0125786163522013 1.27420016406891 0.384325937682521 0.553197891570702 GO:0035254 glutamate receptor binding 1/184 49/18639 0.0204081632653061 2.06732475598935 0.385379634563471 0.553197891570702 GO:0015297 antiporter activity 2/184 135/18639 0.0148148148148148 1.50072463768116 0.385707180455005 0.553197891570702 GO:0099094 ligand-gated monoatomic cation channel activity 2/184 136/18639 0.0147058823529412 1.48968989769821 0.389203579573244 0.556830863844889 GO:0032813 tumor necrosis factor receptor superfamily binding 1/184 50/18639 0.02 2.02597826086957 0.391463020644177 0.558680557857615 GO:0003743 translation initiation factor activity 1/184 51/18639 0.0196078431372549 1.98625319693095 0.397486518637693 0.563105901403398 GO:0005048 signal sequence binding 1/184 51/18639 0.0196078431372549 1.98625319693095 0.397486518637693 0.563105901403398 GO:0005272 sodium channel activity 1/184 51/18639 0.0196078431372549 1.98625319693095 0.397486518637693 0.563105901403398 GO:0140767 enzyme-substrate adaptor activity 2/184 139/18639 0.0143884892086331 1.45753831717235 0.399639627177815 0.564771893664492 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 1/184 52/18639 0.0192307692307692 1.94805602006689 0.403450714924042 0.568767105429504 GO:0004864 protein phosphatase inhibitor activity 1/184 53/18639 0.0188679245283019 1.91130024610336 0.409356190173086 0.575688267445363 GO:0050661 NADP binding 1/184 54/18639 0.0185185185185185 1.87590579710145 0.415203519399824 0.581083860080142 GO:0140463 chromatin-protein adaptor activity 1/184 54/18639 0.0185185185185185 1.87590579710145 0.415203519399824 0.581083860080142 GO:0008374 O-acyltransferase activity 1/184 55/18639 0.0181818181818182 1.84179841897233 0.420993272019164 0.587763553688592 GO:0019212 phosphatase inhibitor activity 1/184 56/18639 0.0178571428571429 1.80890916149068 0.426726011900163 0.592902968457437 GO:0170055 lipid transmembrane transporter activity 1/184 56/18639 0.0178571428571429 1.80890916149068 0.426726011900163 0.592902968457437 GO:0016504 peptidase activator activity 1/184 57/18639 0.0175438596491228 1.77717391304348 0.432402297419743 0.599348987790436 GO:0061980 regulatory RNA binding 1/184 58/18639 0.0172413793103448 1.74653298350825 0.438022681515899 0.605686865828205 GO:0042393 histone binding 3/184 247/18639 0.0121457489878543 1.23035117056856 0.441581026170041 0.606131672307185 GO:0001786 phosphatidylserine binding 1/184 59/18639 0.0169491525423729 1.71693072955048 0.44358771174038 0.606131672307185 GO:0015459 potassium channel regulator activity 1/184 59/18639 0.0169491525423729 1.71693072955048 0.44358771174038 0.606131672307185 GO:0045309 protein phosphorylated amino acid binding 1/184 59/18639 0.0169491525423729 1.71693072955048 0.44358771174038 0.606131672307185 GO:0070063 RNA polymerase binding 1/184 59/18639 0.0169491525423729 1.71693072955048 0.44358771174038 0.606131672307185 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 1/184 60/18639 0.0166666666666667 1.6883152173913 0.449097930310873 0.612213688018125 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 4/184 349/18639 0.0114613180515759 1.16101906067024 0.452885297034262 0.615924003966597 GO:0015026 coreceptor activity 1/184 61/18639 0.0163934426229508 1.66063791874555 0.454553874162684 0.616742110953126 GO:0141003 histone H2AX kinase activity 4/184 354/18639 0.0112994350282486 1.14462048636699 0.463740508104541 0.627591880910777 GO:0003713 transcription coactivator activity 3/184 256/18639 0.01171875 1.18709663722826 0.464722015622513 0.627591880910777 GO:0099106 ion channel regulator activity 2/184 160/18639 0.0125 1.26623641304348 0.470155480442958 0.632060674300422 GO:0140996 histone H3 kinase activity 4/184 357/18639 0.0112044817927171 1.13500182681768 0.470218148701006 0.632060674300422 GO:0008083 growth factor activity 2/184 162/18639 0.0123456790123457 1.2506038647343 0.47661569762847 0.637763547894275 GO:0035173 histone kinase activity 4/184 360/18639 0.0111111111111111 1.12554347826087 0.476667565208178 0.637763547894275 GO:0008235 metalloexopeptidase activity 1/184 66/18639 0.0151515151515152 1.53483201581028 0.481037902017801 0.64212449738173 GO:1990841 promoter-specific chromatin binding 1/184 68/18639 0.0147058823529412 1.48968989769821 0.49126980568638 0.654271768863427 GO:0016247 channel regulator activity 2/184 168/18639 0.0119047619047619 1.20593944099379 0.495707592275886 0.657952598002985 GO:0008080 N-acetyltransferase activity 1/184 69/18639 0.0144927536231884 1.46810018903592 0.496310264237546 0.657952598002985 GO:0008028 monocarboxylic acid transmembrane transporter activity 1/184 70/18639 0.0142857142857143 1.44712732919255 0.501301051064702 0.662421466745612 GO:0141108 transporter regulator activity 2/184 170/18639 0.0117647058823529 1.19175191815857 0.501973360613457 0.662421466745612 GO:0140299 molecular sensor activity 1/184 71/18639 0.0140845070422535 1.4267452541335 0.506242653014408 0.666533606930132 GO:0005244 voltage-gated monoatomic ion channel activity 2/184 173/18639 0.0115606936416185 1.1710856999246 0.511278176838491 0.671633605028745 GO:0008017 microtubule binding 3/184 276/18639 0.0108695652173913 1.10107514177694 0.514564301093774 0.674417610050344 GO:0022832 voltage-gated channel activity 2/184 175/18639 0.0114285714285714 1.15770186335404 0.517418168131602 0.676425148437797 GO:0003678 DNA helicase activity 1/184 74/18639 0.0135135135135135 1.36890423031727 0.520777147153667 0.676425148437797 GO:0003684 damaged DNA binding 1/184 74/18639 0.0135135135135135 1.36890423031727 0.520777147153667 0.676425148437797 GO:0035064 methylated histone binding 1/184 74/18639 0.0135135135135135 1.36890423031727 0.520777147153667 0.676425148437797 GO:0015631 tubulin binding 4/184 385/18639 0.0103896103896104 1.05245623941276 0.529155128967301 0.684090867330531 GO:0051536 iron-sulfur cluster binding 1/184 76/18639 0.0131578947368421 1.33288043478261 0.53022959959183 0.684090867330531 GO:0140034 methylation-dependent protein binding 1/184 76/18639 0.0131578947368421 1.33288043478261 0.53022959959183 0.684090867330531 GO:0003724 RNA helicase activity 1/184 77/18639 0.012987012987013 1.31557029926595 0.534886053488027 0.68703141981351 GO:0051540 metal cluster binding 1/184 77/18639 0.012987012987013 1.31557029926595 0.534886053488027 0.68703141981351 GO:0008186 ATP-dependent activity, acting on RNA 1/184 79/18639 0.0126582278481013 1.28226472206935 0.544061689563331 0.690571487210152 GO:0033293 monocarboxylic acid binding 1/184 79/18639 0.0126582278481013 1.28226472206935 0.544061689563331 0.690571487210152 GO:0008237 metallopeptidase activity 2/184 184/18639 0.0108695652173913 1.10107514177694 0.544411223742375 0.690571487210152 GO:0015276 ligand-gated monoatomic ion channel activity 2/184 186/18639 0.010752688172043 1.08923562412342 0.550266271860125 0.690571487210152 GO:0033192 calmodulin-dependent protein phosphatase activity 1/184 81/18639 0.0123456790123457 1.2506038647343 0.553057275736958 0.690571487210152 GO:0140791 histone H2AXS140 phosphatase activity 1/184 81/18639 0.0123456790123457 1.2506038647343 0.553057275736958 0.690571487210152 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 1/184 81/18639 0.0123456790123457 1.2506038647343 0.553057275736958 0.690571487210152 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 1/184 81/18639 0.0123456790123457 1.2506038647343 0.553057275736958 0.690571487210152 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 1/184 81/18639 0.0123456790123457 1.2506038647343 0.553057275736958 0.690571487210152 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 1/184 81/18639 0.0123456790123457 1.2506038647343 0.553057275736958 0.690571487210152 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 1/184 81/18639 0.0123456790123457 1.2506038647343 0.553057275736958 0.690571487210152 GO:1990439 MAP kinase serine/threonine phosphatase activity 1/184 81/18639 0.0123456790123457 1.2506038647343 0.553057275736958 0.690571487210152 GO:0031406 carboxylic acid binding 2/184 187/18639 0.0106951871657754 1.08341083468961 0.553174045983219 0.690571487210152 GO:0022834 ligand-gated channel activity 2/184 188/18639 0.0106382978723404 1.07764801110083 0.556068618478728 0.691477339594404 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 1/184 82/18639 0.0121951219512195 1.2353525980912 0.557488650953274 0.691477339594404 GO:0033549 MAP kinase phosphatase activity 1/184 82/18639 0.0121951219512195 1.2353525980912 0.557488650953274 0.691477339594404 GO:0043177 organic acid binding 2/184 189/18639 0.0105820105820106 1.07194616977226 0.558949965328339 0.69180531040638 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 1/184 83/18639 0.0120481927710843 1.22046883184914 0.561876326128389 0.692461655655029 GO:0005254 chloride channel activity 1/184 83/18639 0.0120481927710843 1.22046883184914 0.561876326128389 0.692461655655029 GO:0001664 G protein-coupled receptor binding 3/184 297/18639 0.0101010101010101 1.02322134387352 0.564149632036828 0.693784015568695 GO:0017018 myosin phosphatase activity 1/184 84/18639 0.0119047619047619 1.20593944099379 0.566220729878786 0.694852615435113 GO:0050660 flavin adenine dinucleotide binding 1/184 86/18639 0.0116279069767442 1.17789433771486 0.574781416706629 0.703863684017864 GO:0003727 single-stranded RNA binding 1/184 89/18639 0.0112359550561798 1.13819003419638 0.587308388423298 0.717683400652572 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 1/184 91/18639 0.010989010989011 1.11317486860965 0.595455092141415 0.726103466788476 GO:0052689 carboxylic ester hydrolase activity 1/184 92/18639 0.0108695652173913 1.10107514177694 0.599468261380469 0.729458221216655 GO:0051219 phosphoprotein binding 1/184 93/18639 0.010752688172043 1.08923562412342 0.603441833381655 0.732750797677724 GO:0016410 N-acyltransferase activity 1/184 94/18639 0.0106382978723404 1.07764801110083 0.607376196729966 0.734442346673473 GO:0042562 hormone binding 1/184 94/18639 0.0106382978723404 1.07764801110083 0.607376196729966 0.734442346673473 GO:0008276 protein methyltransferase activity 1/184 95/18639 0.0105263157894737 1.06630434782609 0.61127173621779 0.737609735978877 GO:0051015 actin filament binding 2/184 209/18639 0.00956937799043062 0.969367588932806 0.613776987076935 0.739089788605142 GO:0016407 acetyltransferase activity 1/184 96/18639 0.0104166666666667 1.05519701086957 0.61512883288172 0.739177682755996 GO:0043130 ubiquitin binding 1/184 100/18639 0.01 1.01298913043478 0.63018028260948 0.755693367942488 GO:0003924 GTPase activity 3/184 331/18639 0.00906344410876133 0.918117036647839 0.637598101462931 0.763005595539491 GO:0004722 protein serine/threonine phosphatase activity 1/184 103/18639 0.00970873786407767 0.983484592655129 0.641083345499827 0.765591267972934 GO:0019888 protein phosphatase regulator activity 1/184 107/18639 0.00934579439252336 0.946718813490451 0.655124994469122 0.780746900625057 GO:0005496 steroid binding 1/184 108/18639 0.00925925925925926 0.937952898550725 0.658549179717216 0.783212810445578 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 2/184 229/18639 0.00873362445414847 0.884706664135181 0.663270838803556 0.787208510941387 GO:0004222 metalloendopeptidase activity 1/184 110/18639 0.00909090909090909 0.920899209486166 0.665296437319457 0.787994550759521 GO:0005200 structural constituent of cytoskeleton 1/184 112/18639 0.00892857142857143 0.904454580745342 0.671911075725857 0.792580819937848 GO:0043022 ribosome binding 1/184 112/18639 0.00892857142857143 0.904454580745342 0.671911075725857 0.792580819937848 GO:0001221 transcription coregulator binding 1/184 115/18639 0.00869565217391304 0.88086011342155 0.681590030065547 0.802360564924411 GO:0019208 phosphatase regulator activity 1/184 117/18639 0.00854700854700855 0.865802675585284 0.687884353536889 0.808124301512849 GO:0032182 ubiquitin-like protein binding 1/184 120/18639 0.00833333333333333 0.844157608695652 0.697094541038778 0.817283255010981 GO:0003697 single-stranded DNA binding 1/184 121/18639 0.00826446280991736 0.837181099532878 0.700104131429667 0.819150178069529 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 4/184 484/18639 0.00826446280991736 0.837181099532878 0.707327970151471 0.82454174470921 GO:0140104 molecular carrier activity 2/184 249/18639 0.00803212851405622 0.813645887899424 0.707565234214132 0.82454174470921 GO:0140297 DNA-binding transcription factor binding 4/184 488/18639 0.00819672131147541 0.830318959372773 0.7133880794987 0.829654547183599 GO:0019783 ubiquitin-like protein peptidase activity 1/184 127/18639 0.0078740157480315 0.797629236562821 0.71754723199274 0.829861381412847 GO:0042826 histone deacetylase binding 1/184 127/18639 0.0078740157480315 0.797629236562821 0.71754723199274 0.829861381412847 GO:0001216 DNA-binding transcription activator activity 4/184 491/18639 0.00814663951120163 0.825245727441778 0.717873167312152 0.829861381412847 GO:0005543 phospholipid binding 4/184 497/18639 0.00804828973843058 0.815283002361998 0.726689336176344 0.838376120379096 GO:0044325 transmembrane transporter binding 1/184 136/18639 0.00735294117647059 0.744844948849105 0.741837614843619 0.852449585247737 GO:0140789 histone phosphatase activity 1/184 136/18639 0.00735294117647059 0.744844948849105 0.741837614843619 0.852449585247737 GO:0140101 catalytic activity, acting on a tRNA 1/184 139/18639 0.00719424460431655 0.728769158586175 0.749463446358555 0.859503714276279 GO:0016791 phosphatase activity 2/184 273/18639 0.00732600732600733 0.742116579073101 0.754224462020978 0.863250968412129 GO:0020037 heme binding 1/184 142/18639 0.00704225352112676 0.713372627066748 0.756865207420108 0.863909526309012 GO:0005126 cytokine receptor binding 2/184 275/18639 0.00727272727272727 0.736719367588933 0.757809285021363 0.863909526309012 GO:0022843 voltage-gated monoatomic cation channel activity 1/184 143/18639 0.00699300699300699 0.708384007297051 0.75928380512972 0.863909526309012 GO:0008194 UDP-glycosyltransferase activity 1/184 145/18639 0.00689655172413793 0.698613193403298 0.764049446985734 0.867623929975942 GO:0004175 endopeptidase activity 3/184 405/18639 0.00740740740740741 0.75036231884058 0.766271014852127 0.868440483499077 GO:0031267 small GTPase binding 2/184 283/18639 0.00706713780918728 0.71589337839914 0.771702258435324 0.87034986494452 GO:0000510 H3-H4 histone complex chaperone activity 1/184 151/18639 0.00662251655629139 0.670853728764757 0.777790611030134 0.87034986494452 GO:0140584 chromatin extrusion motor activity 1/184 151/18639 0.00662251655629139 0.670853728764757 0.777790611030134 0.87034986494452 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 1/184 151/18639 0.00662251655629139 0.670853728764757 0.777790611030134 0.87034986494452 GO:0140849 ATP-dependent H2AZ histone chaperone activity 1/184 151/18639 0.00662251655629139 0.670853728764757 0.777790611030134 0.87034986494452 GO:0015616 DNA translocase activity 1/184 152/18639 0.00657894736842105 0.666440217391304 0.780002128099069 0.87034986494452 GO:0046906 tetrapyrrole binding 1/184 152/18639 0.00657894736842105 0.666440217391304 0.780002128099069 0.87034986494452 GO:0140674 ATP-dependent histone chaperone activity 1/184 152/18639 0.00657894736842105 0.666440217391304 0.780002128099069 0.87034986494452 GO:0061775 cohesin loader activity 1/184 153/18639 0.0065359477124183 0.662084398976982 0.782191753697044 0.87111143282638 GO:0004386 helicase activity 1/184 155/18639 0.00645161290322581 0.653541374474053 0.786506190481103 0.874231880957842 GO:0140658 ATP-dependent chromatin remodeler activity 1/184 158/18639 0.00632911392405063 0.641132361034673 0.792818979663634 0.879557332525106 GO:0003689 DNA clamp loader activity 1/184 160/18639 0.00625 0.633118206521739 0.796924012698683 0.882417776513101 GO:0004674 protein serine/threonine kinase activity 3/184 433/18639 0.0069284064665127 0.701840044181143 0.80423387188041 0.887839940387955 GO:0140713 histone chaperone activity 1/184 164/18639 0.00609756097560976 0.617676299045599 0.804892956337869 0.887839940387955 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 1/184 167/18639 0.00598802395209581 0.606580317625618 0.810664850498378 0.892503397310595 GO:0003779 actin binding 3/184 443/18639 0.00677200902934537 0.685997153793307 0.81648583961257 0.897203070905068 GO:0051020 GTPase binding 2/184 315/18639 0.00634920634920635 0.643167701863354 0.820562695509197 0.89997198862299 GO:0004721 phosphoprotein phosphatase activity 1/184 175/18639 0.00571428571428571 0.578850931677019 0.825239625435586 0.903387317238198 GO:0043021 ribonucleoprotein complex binding 1/184 177/18639 0.00564971751412429 0.572310243183493 0.828705456112826 0.905466452992841 GO:1901981 phosphatidylinositol phosphate binding 1/184 185/18639 0.00540540540540541 0.54756169212691 0.841898384213563 0.918145785047998 GO:0140597 protein carrier chaperone 1/184 188/18639 0.00531914893617021 0.538824005550416 0.846580808217355 0.9215135727865 GO:0016758 hexosyltransferase activity 1/184 197/18639 0.0050761421319797 0.514207680423747 0.859816457075528 0.932123013026067 GO:0008168 methyltransferase activity 1/184 204/18639 0.00490196078431373 0.496563299232737 0.869320235748368 0.932123013026067 GO:0016755 aminoacyltransferase activity 3/184 496/18639 0.00604838709677419 0.612695038569425 0.871092000999734 0.932123013026067 GO:0106310 protein serine kinase activity 2/184 361/18639 0.00554016620498615 0.561212814645309 0.874480238070446 0.932123013026067 GO:0008094 ATP-dependent activity, acting on DNA 1/184 210/18639 0.00476190476190476 0.482375776397516 0.876954448264697 0.932123013026067 GO:0046982 protein heterodimerization activity 2/184 369/18639 0.00542005420054201 0.549045599151644 0.882184362871087 0.932123013026067 GO:0016741 transferase activity, transferring one-carbon groups 1/184 215/18639 0.00465116279069767 0.471157735085945 0.882976245033204 0.932123013026067 GO:0005525 GTP binding 2/184 378/18639 0.00529100529100529 0.535973084886128 0.890330360944243 0.932123013026067 GO:0140098 catalytic activity, acting on RNA 2/184 387/18639 0.00516795865633075 0.523508594539939 0.897953773180027 0.932123013026067 GO:0000287 magnesium ion binding 1/184 230/18639 0.00434782608695652 0.440430056710775 0.89933866548854 0.932123013026067 GO:0005085 guanyl-nucleotide exchange factor activity 1/184 230/18639 0.00434782608695652 0.440430056710775 0.89933866548854 0.932123013026067 GO:0005125 cytokine activity 1/184 234/18639 0.00427350427350427 0.432901337792642 0.903303531888898 0.932123013026067 GO:0019001 guanyl nucleotide binding 2/184 400/18639 0.005 0.506494565217391 0.908101799160737 0.932123013026067 GO:0032561 guanyl ribonucleotide binding 2/184 400/18639 0.005 0.506494565217391 0.908101799160737 0.932123013026067 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 1/184 243/18639 0.00411522633744856 0.416867954911433 0.911665672359148 0.932123013026067 GO:0004676 3-phosphoinositide-dependent protein kinase activity 1/184 245/18639 0.00408163265306122 0.41346495119787 0.913423953333989 0.932123013026067 GO:0004711 ribosomal protein S6 kinase activity 1/184 245/18639 0.00408163265306122 0.41346495119787 0.913423953333989 0.932123013026067 GO:0035175 histone H3S10 kinase activity 1/184 245/18639 0.00408163265306122 0.41346495119787 0.913423953333989 0.932123013026067 GO:0035979 histone H2AXS139 kinase activity 1/184 245/18639 0.00408163265306122 0.41346495119787 0.913423953333989 0.932123013026067 GO:0044022 histone H3S28 kinase activity 1/184 245/18639 0.00408163265306122 0.41346495119787 0.913423953333989 0.932123013026067 GO:0044023 histone H4S1 kinase activity 1/184 245/18639 0.00408163265306122 0.41346495119787 0.913423953333989 0.932123013026067 GO:0044024 histone H2AS1 kinase activity 1/184 245/18639 0.00408163265306122 0.41346495119787 0.913423953333989 0.932123013026067 GO:0044025 histone H2BS14 kinase activity 1/184 245/18639 0.00408163265306122 0.41346495119787 0.913423953333989 0.932123013026067 GO:0072354 histone H3T3 kinase activity 1/184 245/18639 0.00408163265306122 0.41346495119787 0.913423953333989 0.932123013026067 GO:0072371 histone H2AS121 kinase activity 1/184 245/18639 0.00408163265306122 0.41346495119787 0.913423953333989 0.932123013026067 GO:0072518 Rho-dependent protein serine/threonine kinase activity 1/184 245/18639 0.00408163265306122 0.41346495119787 0.913423953333989 0.932123013026067 GO:0140823 histone H2BS36 kinase activity 1/184 245/18639 0.00408163265306122 0.41346495119787 0.913423953333989 0.932123013026067 GO:0140855 histone H3S57 kinase activity 1/184 245/18639 0.00408163265306122 0.41346495119787 0.913423953333989 0.932123013026067 GO:0140995 histone H2A kinase activity 1/184 245/18639 0.00408163265306122 0.41346495119787 0.913423953333989 0.932123013026067 GO:0140997 histone H4 kinase activity 1/184 245/18639 0.00408163265306122 0.41346495119787 0.913423953333989 0.932123013026067 GO:0140998 histone H2B kinase activity 1/184 245/18639 0.00408163265306122 0.41346495119787 0.913423953333989 0.932123013026067 GO:1990244 histone H2AT120 kinase activity 1/184 245/18639 0.00408163265306122 0.41346495119787 0.913423953333989 0.932123013026067 GO:0004677 DNA-dependent protein kinase activity 1/184 246/18639 0.0040650406504065 0.411784199363733 0.914289996205934 0.932123013026067 GO:0140857 histone H3T45 kinase activity 1/184 246/18639 0.0040650406504065 0.411784199363733 0.914289996205934 0.932123013026067 GO:0035402 histone H3T11 kinase activity 1/184 247/18639 0.00404858299595142 0.410117056856187 0.915147422438637 0.932123013026067 GO:0035403 histone H3T6 kinase activity 1/184 247/18639 0.00404858299595142 0.410117056856187 0.915147422438637 0.932123013026067 GO:0004679 AMP-activated protein kinase activity 1/184 248/18639 0.00403225806451613 0.408463359046283 0.915996317298972 0.932123013026067 GO:0016757 glycosyltransferase activity 1/184 267/18639 0.00374531835205993 0.379396678065462 0.930611835724229 0.945331530841132 GO:0005096 GTPase activator activity 1/184 271/18639 0.003690036900369 0.373796727097706 0.933350330820716 0.946449984586621 GO:0004842 ubiquitin-protein transferase activity 2/184 449/18639 0.0044543429844098 0.451220102643556 0.938487316661587 0.949992415114531 GO:0035091 phosphatidylinositol binding 1/184 284/18639 0.00352112676056338 0.356686313533374 0.94152940623077 0.95140558881361 GO:0019787 ubiquitin-like protein transferase activity 2/184 479/18639 0.00417536534446764 0.42295997095398 0.952116012771001 0.960424180421708 GO:0030695 GTPase regulator activity 2/184 489/18639 0.00408997955010225 0.414310482795412 0.955983147859951 0.96134275130408 GO:0060589 nucleoside-triphosphatase regulator activity 2/184 490/18639 0.00408163265306122 0.41346495119787 0.956353083044717 0.96134275130408 GO:0140097 catalytic activity, acting on DNA 1/184 336/18639 0.00297619047619048 0.301484860248447 0.965398887276857 0.968750966746568 GO:0061630 ubiquitin protein ligase activity 1/184 353/18639 0.0028328611898017 0.286965759329967 0.970861959361585 0.972544562410739 GO:0061659 ubiquitin-like protein ligase activity 1/184 372/18639 0.00268817204301075 0.272308906030856 0.9759581383968 0.9759581383968