ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0015453 oxidoreduction-driven active transmembrane transporter activity 19/336 68/18639 0.279411764705882 15.499868697479 6.59777668816846e-18 4.7899858756103e-15 GO:0008137 NADH dehydrogenase (ubiquinone) activity 15/336 41/18639 0.365853658536585 20.2950783972125 2.0983705721824e-16 7.61708517702211e-14 GO:0003954 NADH dehydrogenase activity 15/336 44/18639 0.340909090909091 18.9113230519481 7.24297700277967e-16 1.75280043467268e-13 GO:0022853 active monoatomic ion transmembrane transporter activity 21/336 118/18639 0.177966101694915 9.87235169491525 2.48183760158802e-15 4.50453524688225e-13 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 16/336 58/18639 0.275862068965517 15.3029556650246 3.51106524459264e-15 5.09806673514851e-13 GO:0015399 primary active transmembrane transporter activity 23/336 166/18639 0.13855421686747 7.68604776247849 3.18441589950921e-14 3.85314323840614e-12 GO:0009055 electron transfer activity 19/336 116/18639 0.163793103448276 9.08612992610837 2.60859684089623e-13 2.70548758070095e-11 GO:0015078 proton transmembrane transporter activity 23/336 185/18639 0.124324324324324 6.89666988416988 3.35334895166355e-13 3.04316417363467e-11 GO:0016651 oxidoreductase activity, acting on NAD(P)H 16/336 88/18639 0.181818181818182 10.086038961039 3.8988771508431e-12 3.14509423501343e-10 GO:0022804 active transmembrane transporter activity 30/336 457/18639 0.0656455142231947 3.64156767739919 1.15870849378536e-09 8.41222366488172e-08 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 8/336 61/18639 0.131147540983607 7.2751756440281 1.31539738403311e-05 0.000868162273461851 GO:0001618 virus receptor activity 9/336 81/18639 0.111111111111111 6.16369047619048 1.5063092787757e-05 0.0009113171136593 GO:0140272 exogenous protein binding 9/336 82/18639 0.109756097560976 6.08852351916376 1.66553898951429e-05 0.000930139466451827 GO:0016853 isomerase activity 12/336 180/18639 0.0666666666666667 3.69821428571429 0.000107519320573925 0.00520973901853739 GO:0004364 glutathione transferase activity 5/336 27/18639 0.185185185185185 10.2728174603175 0.000107639235920194 0.00520973901853739 GO:0005178 integrin binding 11/336 161/18639 0.0683229813664596 3.79009538598048 0.000166994529169237 0.00757737676105411 GO:0003823 antigen binding 11/336 174/18639 0.0632183908045977 3.50692733990148 0.000327694699743945 0.0139944912949473 GO:0044183 protein folding chaperone 7/336 75/18639 0.0933333333333333 5.1775 0.000403506368503917 0.0162747568629913 GO:0098631 cell adhesion mediator activity 7/336 76/18639 0.0921052631578947 5.109375 0.000437681189745974 0.0167240286187146 GO:0050786 RAGE receptor binding 3/336 11/18639 0.272727272727273 15.1290584415584 0.000860366962250731 0.0312313207297015 GO:0005201 extracellular matrix structural constituent 10/336 168/18639 0.0595238095238095 3.30197704081633 0.000965996387132115 0.033395875097996 GO:0030020 extracellular matrix structural constituent conferring tensile strength 5/336 44/18639 0.113636363636364 6.30377435064935 0.00112722279319783 0.0371983521755284 GO:0042605 peptide antigen binding 5/336 45/18639 0.111111111111111 6.16369047619048 0.00124965458324329 0.0394456185841143 GO:0051082 unfolded protein binding 8/336 121/18639 0.0661157024793388 3.66765053128689 0.00158174571200176 0.0478478077880534 GO:0005518 collagen binding 6/336 72/18639 0.0833333333333333 4.62276785714286 0.00188773026310916 0.0548196868406901 GO:0098632 cell-cell adhesion mediator activity 5/336 55/18639 0.0909090909090909 5.04301948051948 0.00307372954658427 0.0852899315075826 GO:0002020 protease binding 8/336 136/18639 0.0588235294117647 3.26313025210084 0.00328307892096343 0.0852899315075826 GO:0016829 lyase activity 10/336 200/18639 0.05 2.77366071428571 0.0034935724220713 0.0852899315075826 GO:0008514 organic anion transmembrane transporter activity 12/336 269/18639 0.0446096654275093 2.47464152947424 0.00366754392034914 0.0852899315075826 GO:0035615 clathrin adaptor activity 3/336 18/18639 0.166666666666667 9.24553571428571 0.00387500177970849 0.0852899315075826 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 4/336 36/18639 0.111111111111111 6.16369047619048 0.00387681506852648 0.0852899315075826 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 4/336 36/18639 0.111111111111111 6.16369047619048 0.00387681506852648 0.0852899315075826 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 4/336 36/18639 0.111111111111111 6.16369047619048 0.00387681506852648 0.0852899315075826 GO:0008301 DNA binding, bending 3/336 19/18639 0.157894736842105 8.75892857142857 0.00454071380348078 0.0929268696896489 GO:0034987 immunoglobulin receptor binding 3/336 19/18639 0.157894736842105 8.75892857142857 0.00454071380348078 0.0929268696896489 GO:0016209 antioxidant activity 6/336 86/18639 0.0697674418604651 3.87022425249169 0.00460794395155284 0.0929268696896489 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 4/336 39/18639 0.102564102564103 5.68956043956044 0.00518952774533203 0.101826949813812 GO:0140662 ATP-dependent protein folding chaperone 4/336 40/18639 0.1 5.54732142857143 0.0056856628387884 0.108626084762115 GO:0140312 cargo adaptor activity 3/336 21/18639 0.142857142857143 7.92474489795918 0.00606883403451678 0.112973679719466 GO:0016859 cis-trans isomerase activity 4/336 42/18639 0.0952380952380952 5.28316326530612 0.00677068099775772 0.122887860109303 GO:0004602 glutathione peroxidase activity 3/336 23/18639 0.130434782608696 7.23563664596273 0.00786949697139679 0.136115652517609 GO:0045296 cadherin binding 13/336 334/18639 0.0389221556886228 2.1591370829769 0.00787445923655591 0.136115652517609 GO:0031072 heat shock protein binding 7/336 131/18639 0.0534351145038168 2.96421755725191 0.00967978704845945 0.163430823190269 GO:0005537 D-mannose binding 3/336 25/18639 0.12 6.65678571428571 0.00995297011367294 0.164224006875604 GO:0030247 polysaccharide binding 3/336 26/18639 0.115384615384615 6.40075549450549 0.0111033646790375 0.175240059934375 GO:0050750 low-density lipoprotein particle receptor binding 3/336 26/18639 0.115384615384615 6.40075549450549 0.0111033646790375 0.175240059934375 GO:0019838 growth factor binding 7/336 136/18639 0.0514705882352941 2.85523897058824 0.0117397518545164 0.180574552708013 GO:0003714 transcription corepressor activity 9/336 204/18639 0.0441176470588235 2.44734768907563 0.0119388134021827 0.180574552708013 GO:0023026 MHC class II protein complex binding 3/336 27/18639 0.111111111111111 6.16369047619048 0.0123273289536182 0.182645731027077 GO:0030246 carbohydrate binding 11/336 280/18639 0.0392857142857143 2.17930484693878 0.0130587528625678 0.184997313642856 GO:0015658 branched-chain amino acid transmembrane transporter activity 2/336 10/18639 0.2 11.0946428571429 0.0132504962939787 0.184997313642856 GO:0032395 MHC class II receptor activity 2/336 10/18639 0.2 11.0946428571429 0.0132504962939787 0.184997313642856 GO:0016835 carbon-oxygen lyase activity 5/336 79/18639 0.0632911392405063 3.51096292947559 0.0140548885218444 0.190472150408972 GO:0033218 amide binding 10/336 247/18639 0.0404858299595142 2.24587912087912 0.01448262946873 0.190472150408972 GO:0004629 phospholipase C activity 3/336 29/18639 0.103448275862069 5.73860837438424 0.014998638713533 0.190472150408972 GO:0016860 intramolecular oxidoreductase activity 4/336 53/18639 0.0754716981132075 4.1866576819407 0.0151879911905004 0.190472150408972 GO:0042277 peptide binding 10/336 249/18639 0.0401606425702811 2.22783993115318 0.0152421506124974 0.190472150408972 GO:0015173 aromatic amino acid transmembrane transporter activity 2/336 11/18639 0.181818181818182 10.086038961039 0.016003858367696 0.190472150408972 GO:0015217 ADP transmembrane transporter activity 2/336 11/18639 0.181818181818182 10.086038961039 0.016003858367696 0.190472150408972 GO:0042608 T cell receptor binding 2/336 11/18639 0.181818181818182 10.086038961039 0.016003858367696 0.190472150408972 GO:0048407 platelet-derived growth factor binding 2/336 11/18639 0.181818181818182 10.086038961039 0.016003858367696 0.190472150408972 GO:0048019 receptor antagonist activity 3/336 30/18639 0.1 5.54732142857143 0.0164470380121471 0.192589509626109 GO:0008135 translation factor activity, RNA binding 5/336 83/18639 0.0602409638554217 3.34175989672978 0.0170919162827213 0.194059310155618 GO:0180051 translation factor activity 5/336 84/18639 0.0595238095238095 3.30197704081633 0.0179139036841565 0.194059310155618 GO:0070325 lipoprotein particle receptor binding 3/336 31/18639 0.0967741935483871 5.36837557603687 0.0179711246051246 0.194059310155618 GO:0003712 transcription coregulator activity 16/336 495/18639 0.0323232323232323 1.79307359307359 0.0181417718662839 0.194059310155618 GO:0004300 enoyl-CoA hydratase activity 2/336 12/18639 0.166666666666667 9.24553571428571 0.0189782520951087 0.194059310155618 GO:0005049 nuclear export signal receptor activity 2/336 12/18639 0.166666666666667 9.24553571428571 0.0189782520951087 0.194059310155618 GO:0016840 carbon-nitrogen lyase activity 2/336 12/18639 0.166666666666667 9.24553571428571 0.0189782520951087 0.194059310155618 GO:0042301 phosphate ion binding 2/336 12/18639 0.166666666666667 9.24553571428571 0.0189782520951087 0.194059310155618 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 2/336 12/18639 0.166666666666667 9.24553571428571 0.0189782520951087 0.194059310155618 GO:0046943 carboxylic acid transmembrane transporter activity 8/336 188/18639 0.0425531914893617 2.36056231003039 0.0209700176149983 0.208982993948793 GO:0019956 chemokine binding 3/336 33/18639 0.0909090909090909 5.04301948051948 0.0212473312417527 0.208982993948793 GO:0005342 organic acid transmembrane transporter activity 8/336 189/18639 0.0423280423280423 2.34807256235828 0.0215671261458371 0.208982993948793 GO:0017154 semaphorin receptor activity 2/336 13/18639 0.153846153846154 8.53434065934066 0.022164862994569 0.208982993948793 GO:0035325 Toll-like receptor binding 2/336 13/18639 0.153846153846154 8.53434065934066 0.022164862994569 0.208982993948793 GO:0086080 protein binding involved in heterotypic cell-cell adhesion 2/336 13/18639 0.153846153846154 8.53434065934066 0.022164862994569 0.208982993948793 GO:0004714 transmembrane receptor protein tyrosine kinase activity 4/336 60/18639 0.0666666666666667 3.69821428571429 0.0229477950441586 0.213591015411015 GO:0016836 hydro-lyase activity 4/336 61/18639 0.0655737704918033 3.63758782201405 0.0242201913761173 0.222580492899508 GO:0005347 ATP transmembrane transporter activity 2/336 14/18639 0.142857142857143 7.92474489795918 0.0255551209021895 0.231912722187369 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 6/336 128/18639 0.046875 2.60030691964286 0.0285653944922502 0.246001673201853 GO:0023023 MHC protein complex binding 3/336 37/18639 0.0810810810810811 4.49782818532819 0.0287135675170589 0.246001673201853 GO:0004129 cytochrome-c oxidase activity 2/336 15/18639 0.133333333333333 7.39642857142857 0.0291406940707429 0.246001673201853 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 2/336 15/18639 0.133333333333333 7.39642857142857 0.0291406940707429 0.246001673201853 GO:0033130 acetylcholine receptor binding 2/336 15/18639 0.133333333333333 7.39642857142857 0.0291406940707429 0.246001673201853 GO:0140776 protein-containing complex destabilizing activity 2/336 15/18639 0.133333333333333 7.39642857142857 0.0291406940707429 0.246001673201853 GO:0050840 extracellular matrix binding 4/336 67/18639 0.0597014925373134 3.31183368869936 0.0327421936799953 0.265502099434075 GO:0000062 fatty-acyl-CoA binding 2/336 16/18639 0.125 6.93415178571429 0.0329134834009184 0.265502099434075 GO:0016675 oxidoreductase activity, acting on a heme group of donors 2/336 16/18639 0.125 6.93415178571429 0.0329134834009184 0.265502099434075 GO:0022858 alanine transmembrane transporter activity 2/336 16/18639 0.125 6.93415178571429 0.0329134834009184 0.265502099434075 GO:0004659 prenyltransferase activity 2/336 17/18639 0.117647058823529 6.52626050420168 0.0368656168021007 0.275922039157991 GO:0005092 GDP-dissociation inhibitor activity 2/336 17/18639 0.117647058823529 6.52626050420168 0.0368656168021007 0.275922039157991 GO:0016018 cyclosporin A binding 2/336 17/18639 0.117647058823529 6.52626050420168 0.0368656168021007 0.275922039157991 GO:0036041 long-chain fatty acid binding 2/336 17/18639 0.117647058823529 6.52626050420168 0.0368656168021007 0.275922039157991 GO:0046965 nuclear retinoid X receptor binding 2/336 17/18639 0.117647058823529 6.52626050420168 0.0368656168021007 0.275922039157991 GO:0048038 quinone binding 2/336 17/18639 0.117647058823529 6.52626050420168 0.0368656168021007 0.275922039157991 GO:1901567 fatty acid derivative binding 2/336 17/18639 0.117647058823529 6.52626050420168 0.0368656168021007 0.275922039157991 GO:0015175 neutral L-amino acid transmembrane transporter activity 3/336 41/18639 0.0731707317073171 4.05901567944251 0.0373895230214554 0.276987690954863 GO:0003746 translation elongation factor activity 2/336 18/18639 0.111111111111111 6.16369047619048 0.0409894436798997 0.294636991204032 GO:0016854 racemase and epimerase activity 2/336 18/18639 0.111111111111111 6.16369047619048 0.0409894436798997 0.294636991204032 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 2/336 18/18639 0.111111111111111 6.16369047619048 0.0409894436798997 0.294636991204032 GO:0019205 nucleobase-containing compound kinase activity 3/336 44/18639 0.0681818181818182 3.78226461038961 0.0446752364646278 0.310108362751322 GO:0030547 signaling receptor inhibitor activity 3/336 44/18639 0.0681818181818182 3.78226461038961 0.0446752364646278 0.310108362751322 GO:0005346 purine ribonucleotide transmembrane transporter activity 2/336 19/18639 0.105263157894737 5.83928571428571 0.0452775295477137 0.310108362751322 GO:0005520 insulin-like growth factor binding 2/336 19/18639 0.105263157894737 5.83928571428571 0.0452775295477137 0.310108362751322 GO:0120227 acyl-CoA binding 2/336 19/18639 0.105263157894737 5.83928571428571 0.0452775295477137 0.310108362751322 GO:0030291 protein serine/threonine kinase inhibitor activity 3/336 46/18639 0.0652173913043478 3.61781832298137 0.0498943777872377 0.338535684799389 GO:0019199 transmembrane receptor protein kinase activity 4/336 78/18639 0.0512820512820513 2.84478021978022 0.0523870262222136 0.352157231827103 GO:0001846 opsonin binding 2/336 21/18639 0.0952380952380952 5.28316326530612 0.0543177893623138 0.361786376853576 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 3/336 48/18639 0.0625 3.46707589285714 0.0553963177591191 0.365615697210186 GO:0005006 epidermal growth factor receptor activity 3/336 50/18639 0.06 3.32839285714286 0.0611744451600623 0.394776932754181 GO:0015605 organophosphate ester transmembrane transporter activity 3/336 50/18639 0.06 3.32839285714286 0.0611744451600623 0.394776932754181 GO:1901681 sulfur compound binding 9/336 275/18639 0.0327272727272727 1.81548701298701 0.0621621741736404 0.394776932754181 GO:0000295 adenine nucleotide transmembrane transporter activity 2/336 23/18639 0.0869565217391304 4.82375776397515 0.0639310453093469 0.394776932754181 GO:0017134 fibroblast growth factor binding 2/336 23/18639 0.0869565217391304 4.82375776397515 0.0639310453093469 0.394776932754181 GO:0070577 lysine-acetylated histone binding 2/336 23/18639 0.0869565217391304 4.82375776397515 0.0639310453093469 0.394776932754181 GO:0003743 translation initiation factor activity 3/336 51/18639 0.0588235294117647 3.26313025210084 0.0641648458195501 0.394776932754181 GO:0005021 vascular endothelial growth factor receptor activity 3/336 51/18639 0.0588235294117647 3.26313025210084 0.0641648458195501 0.394776932754181 GO:0005080 protein kinase C binding 3/336 52/18639 0.0576923076923077 3.20037774725275 0.0672215446399282 0.410107910996537 GO:0140033 acetylation-dependent protein binding 2/336 24/18639 0.0833333333333333 4.62276785714286 0.0689361104864887 0.415198560949959 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 5/336 122/18639 0.040983606557377 2.27349238875878 0.0700041601250145 0.415198560949959 GO:0004864 protein phosphatase inhibitor activity 3/336 53/18639 0.0566037735849057 3.13999326145553 0.0703435578468939 0.415198560949959 GO:1901505 carbohydrate derivative transmembrane transporter activity 3/336 53/18639 0.0566037735849057 3.13999326145553 0.0703435578468939 0.415198560949959 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 3/336 54/18639 0.0555555555555556 3.08184523809524 0.0735298731575299 0.420087871170081 GO:0004709 MAP kinase kinase kinase activity 2/336 25/18639 0.08 4.43785714285714 0.0740650792145597 0.420087871170081 GO:0015645 fatty acid ligase activity 2/336 25/18639 0.08 4.43785714285714 0.0740650792145597 0.420087871170081 GO:0042974 nuclear retinoic acid receptor binding 2/336 25/18639 0.08 4.43785714285714 0.0740650792145597 0.420087871170081 GO:0120515 fatty acid-CoA ligase activity 2/336 25/18639 0.08 4.43785714285714 0.0740650792145597 0.420087871170081 GO:0004857 enzyme inhibitor activity 12/336 416/18639 0.0288461538461538 1.60018887362637 0.0750328567464305 0.422277937968283 GO:0005112 Notch binding 2/336 26/18639 0.0769230769230769 4.26717032967033 0.0793118887591865 0.4339271165745 GO:0015216 purine nucleotide transmembrane transporter activity 2/336 26/18639 0.0769230769230769 4.26717032967033 0.0793118887591865 0.4339271165745 GO:0050681 nuclear androgen receptor binding 2/336 26/18639 0.0769230769230769 4.26717032967033 0.0793118887591865 0.4339271165745 GO:0042826 histone deacetylase binding 5/336 127/18639 0.0393700787401575 2.1839848143982 0.0800262972762464 0.4339271165745 GO:0019212 phosphatase inhibitor activity 3/336 56/18639 0.0535714285714286 2.97177933673469 0.0800912308828967 0.4339271165745 GO:0004601 peroxidase activity 3/336 57/18639 0.0526315789473684 2.91964285714286 0.0834641246166371 0.442236650882567 GO:0015932 nucleobase-containing compound transmembrane transporter activity 3/336 57/18639 0.0526315789473684 2.91964285714286 0.0834641246166371 0.442236650882567 GO:0001671 ATPase activator activity 2/336 27/18639 0.0740740740740741 4.10912698412698 0.084670653543632 0.442236650882567 GO:0015252 proton channel activity 2/336 27/18639 0.0740740740740741 4.10912698412698 0.084670653543632 0.442236650882567 GO:0016405 CoA-ligase activity 2/336 27/18639 0.0740740740740741 4.10912698412698 0.084670653543632 0.442236650882567 GO:0015459 potassium channel regulator activity 3/336 59/18639 0.0508474576271186 2.82067191283293 0.0903888126984764 0.46084785009102 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 3/336 59/18639 0.0508474576271186 2.82067191283293 0.0903888126984764 0.46084785009102 GO:0070063 RNA polymerase binding 3/336 59/18639 0.0508474576271186 2.82067191283293 0.0903888126984764 0.46084785009102 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 5/336 132/18639 0.0378787878787879 2.10125811688312 0.0907730613815645 0.46084785009102 GO:0042626 ATPase-coupled transmembrane transporter activity 4/336 98/18639 0.0408163265306122 2.26421282798834 0.101116853855268 0.497223613531059 GO:0015179 L-amino acid transmembrane transporter activity 3/336 62/18639 0.0483870967741935 2.68418778801843 0.101205974688712 0.497223613531059 GO:0001968 fibronectin binding 2/336 30/18639 0.0666666666666667 3.69821428571429 0.101362389535257 0.497223613531059 GO:0008106 alcohol dehydrogenase (NADP+) activity 2/336 30/18639 0.0666666666666667 3.69821428571429 0.101362389535257 0.497223613531059 GO:0015215 nucleotide transmembrane transporter activity 2/336 30/18639 0.0666666666666667 3.69821428571429 0.101362389535257 0.497223613531059 GO:0005507 copper ion binding 3/336 63/18639 0.0476190476190476 2.64158163265306 0.104921727035464 0.507821158851647 GO:1901682 sulfur compound transmembrane transporter activity 3/336 63/18639 0.0476190476190476 2.64158163265306 0.104921727035464 0.507821158851647 GO:0005310 dicarboxylic acid transmembrane transporter activity 2/336 31/18639 0.0645161290322581 3.57891705069124 0.107113511254577 0.508264112227599 GO:0016878 acid-thiol ligase activity 2/336 31/18639 0.0645161290322581 3.57891705069124 0.107113511254577 0.508264112227599 GO:0072349 modified amino acid transmembrane transporter activity 2/336 31/18639 0.0645161290322581 3.57891705069124 0.107113511254577 0.508264112227599 GO:0004713 protein tyrosine kinase activity 5/336 140/18639 0.0357142857142857 1.9811862244898 0.109426938162274 0.515869851336436 GO:0031369 translation initiation factor binding 2/336 32/18639 0.0625 3.46707589285714 0.11294966765194 0.525650376380183 GO:0140142 nucleocytoplasmic carrier activity 2/336 32/18639 0.0625 3.46707589285714 0.11294966765194 0.525650376380183 GO:0140416 transcription regulator inhibitor activity 2/336 33/18639 0.0606060606060606 3.36201298701299 0.118865947420339 0.548639141079692 GO:0019955 cytokine binding 5/336 144/18639 0.0347222222222222 1.92615327380952 0.119400804807977 0.548639141079692 GO:0016500 protein-hormone receptor activity 3/336 67/18639 0.0447761194029851 2.48387526652452 0.120302997237911 0.549308025124048 GO:0044389 ubiquitin-like protein ligase binding 9/336 322/18639 0.0279503105590062 1.55049356699201 0.129467866247633 0.587460443098636 GO:0005343 organic acid:sodium symporter activity 2/336 35/18639 0.0571428571428571 3.16989795918367 0.130919970517723 0.59035961860787 GO:0097110 scaffold protein binding 3/336 70/18639 0.0428571428571429 2.37742346938776 0.132349020814817 0.593119685873809 GO:0004620 phospholipase activity 4/336 109/18639 0.036697247706422 2.03571428571429 0.134372366824397 0.598492873095165 GO:0004033 aldo-keto reductase (NADPH) activity 2/336 36/18639 0.0555555555555556 3.08184523809524 0.137048618801857 0.606690836891148 GO:0043539 protein serine/threonine kinase activator activity 3/336 73/18639 0.0410958904109589 2.27972113502935 0.144795338663361 0.632387016769835 GO:0005539 glycosaminoglycan binding 7/336 242/18639 0.0289256198347107 1.60459710743802 0.148591678122476 0.632387016769835 GO:0003684 damaged DNA binding 3/336 74/18639 0.0405405405405405 2.24891409266409 0.149027300331919 0.632387016769835 GO:0048029 monosaccharide binding 3/336 74/18639 0.0405405405405405 2.24891409266409 0.149027300331919 0.632387016769835 GO:0000217 DNA secondary structure binding 2/336 39/18639 0.0512820512820513 2.84478021978022 0.155789429327782 0.632387016769835 GO:0015036 disulfide oxidoreductase activity 2/336 40/18639 0.05 2.77366071428571 0.16214106909055 0.632387016769835 GO:0003680 minor groove of adenine-thymine-rich DNA binding 1/336 10/18639 0.1 5.54732142857143 0.166362084566456 0.632387016769835 GO:0004090 carbonyl reductase (NADPH) activity 1/336 10/18639 0.1 5.54732142857143 0.166362084566456 0.632387016769835 GO:0004862 cAMP-dependent protein kinase inhibitor activity 1/336 10/18639 0.1 5.54732142857143 0.166362084566456 0.632387016769835 GO:0005345 purine nucleobase transmembrane transporter activity 1/336 10/18639 0.1 5.54732142857143 0.166362084566456 0.632387016769835 GO:0005528 FK506 binding 1/336 10/18639 0.1 5.54732142857143 0.166362084566456 0.632387016769835 GO:0015187 glycine transmembrane transporter activity 1/336 10/18639 0.1 5.54732142857143 0.166362084566456 0.632387016769835 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines 1/336 10/18639 0.1 5.54732142857143 0.166362084566456 0.632387016769835 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity 1/336 10/18639 0.1 5.54732142857143 0.166362084566456 0.632387016769835 GO:0019531 oxalate transmembrane transporter activity 1/336 10/18639 0.1 5.54732142857143 0.166362084566456 0.632387016769835 GO:0031957 very long-chain fatty acid-CoA ligase activity 1/336 10/18639 0.1 5.54732142857143 0.166362084566456 0.632387016769835 GO:0035374 chondroitin sulfate binding 1/336 10/18639 0.1 5.54732142857143 0.166362084566456 0.632387016769835 GO:0042975 peroxisome proliferator activated receptor binding 1/336 10/18639 0.1 5.54732142857143 0.166362084566456 0.632387016769835 GO:0043208 glycosphingolipid binding 1/336 10/18639 0.1 5.54732142857143 0.166362084566456 0.632387016769835 GO:0043295 glutathione binding 1/336 10/18639 0.1 5.54732142857143 0.166362084566456 0.632387016769835 GO:0072582 17-beta-hydroxysteroid dehydrogenase (NADP+) activity 1/336 10/18639 0.1 5.54732142857143 0.166362084566456 0.632387016769835 GO:0140135 mechanosensitive monoatomic cation channel activity 1/336 10/18639 0.1 5.54732142857143 0.166362084566456 0.632387016769835 GO:0001530 lipopolysaccharide binding 2/336 41/18639 0.0487804878048781 2.70601045296167 0.168538584273581 0.632387016769835 GO:0016877 ligase activity, forming carbon-sulfur bonds 2/336 41/18639 0.0487804878048781 2.70601045296167 0.168538584273581 0.632387016769835 GO:0015370 solute:sodium symporter activity 3/336 79/18639 0.0379746835443038 2.10657775768535 0.170755601144726 0.632387016769835 GO:0033293 monocarboxylic acid binding 3/336 79/18639 0.0379746835443038 2.10657775768535 0.170755601144726 0.632387016769835 GO:0042056 chemoattractant activity 2/336 42/18639 0.0476190476190476 2.64158163265306 0.174978272559173 0.632387016769835 GO:0019887 protein kinase regulator activity 7/336 255/18639 0.0274509803921569 1.52279411764706 0.178551152522152 0.632387016769835 GO:0015101 organic cation transmembrane transporter activity 3/336 81/18639 0.037037037037037 2.05456349206349 0.179689411163529 0.632387016769835 GO:0031625 ubiquitin protein ligase binding 8/336 302/18639 0.0264900662251656 1.46948912015137 0.180360433039712 0.632387016769835 GO:0000099 sulfur amino acid transmembrane transporter activity 1/336 11/18639 0.0909090909090909 5.04301948051948 0.181397907186333 0.632387016769835 GO:0003953 NAD+ nucleosidase activity 1/336 11/18639 0.0909090909090909 5.04301948051948 0.181397907186333 0.632387016769835 GO:0008271 secondary active sulfate transmembrane transporter activity 1/336 11/18639 0.0909090909090909 5.04301948051948 0.181397907186333 0.632387016769835 GO:0008503 benzodiazepine receptor activity 1/336 11/18639 0.0909090909090909 5.04301948051948 0.181397907186333 0.632387016769835 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity 1/336 11/18639 0.0909090909090909 5.04301948051948 0.181397907186333 0.632387016769835 GO:0015205 nucleobase transmembrane transporter activity 1/336 11/18639 0.0909090909090909 5.04301948051948 0.181397907186333 0.632387016769835 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives 1/336 11/18639 0.0909090909090909 5.04301948051948 0.181397907186333 0.632387016769835 GO:0034056 estrogen response element binding 1/336 11/18639 0.0909090909090909 5.04301948051948 0.181397907186333 0.632387016769835 GO:0047676 arachidonate-CoA ligase activity 1/336 11/18639 0.0909090909090909 5.04301948051948 0.181397907186333 0.632387016769835 GO:0097493 structural molecule activity conferring elasticity 1/336 11/18639 0.0909090909090909 5.04301948051948 0.181397907186333 0.632387016769835 GO:0140031 phosphorylation-dependent protein binding 1/336 11/18639 0.0909090909090909 5.04301948051948 0.181397907186333 0.632387016769835 GO:1900750 oligopeptide binding 1/336 11/18639 0.0909090909090909 5.04301948051948 0.181397907186333 0.632387016769835 GO:0016874 ligase activity 5/336 167/18639 0.029940119760479 1.660874679213 0.184198916547194 0.632387016769835 GO:0001540 amyloid-beta binding 3/336 83/18639 0.036144578313253 2.00505593803787 0.188747290451523 0.632387016769835 GO:0004860 protein kinase inhibitor activity 3/336 84/18639 0.0357142857142857 1.9811862244898 0.193319779416586 0.632387016769835 GO:0051539 4 iron, 4 sulfur cluster binding 2/336 45/18639 0.0444444444444444 2.46547619047619 0.194515102319025 0.632387016769835 GO:0000340 RNA 7-methylguanosine cap binding 1/336 12/18639 0.0833333333333333 4.62276785714286 0.196163330376444 0.632387016769835 GO:0004032 aldose reductase (NADPH) activity 1/336 12/18639 0.0833333333333333 4.62276785714286 0.196163330376444 0.632387016769835 GO:0005078 MAP-kinase scaffold activity 1/336 12/18639 0.0833333333333333 4.62276785714286 0.196163330376444 0.632387016769835 GO:0005095 GTPase inhibitor activity 1/336 12/18639 0.0833333333333333 4.62276785714286 0.196163330376444 0.632387016769835 GO:0005436 sodium:phosphate symporter activity 1/336 12/18639 0.0833333333333333 4.62276785714286 0.196163330376444 0.632387016769835 GO:0005527 macrolide binding 1/336 12/18639 0.0833333333333333 4.62276785714286 0.196163330376444 0.632387016769835 GO:0008499 N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity 1/336 12/18639 0.0833333333333333 4.62276785714286 0.196163330376444 0.632387016769835 GO:0008603 cAMP-dependent protein kinase regulator activity 1/336 12/18639 0.0833333333333333 4.62276785714286 0.196163330376444 0.632387016769835 GO:0015269 calcium-activated potassium channel activity 1/336 12/18639 0.0833333333333333 4.62276785714286 0.196163330376444 0.632387016769835 GO:0016208 AMP binding 1/336 12/18639 0.0833333333333333 4.62276785714286 0.196163330376444 0.632387016769835 GO:0004519 endonuclease activity 4/336 127/18639 0.031496062992126 1.74718785151856 0.19666899395777 0.632387016769835 GO:0008201 heparin binding 5/336 172/18639 0.0290697674418605 1.61259343853821 0.199740623123066 0.632387016769835 GO:0140030 modification-dependent protein binding 5/336 173/18639 0.0289017341040462 1.60327208918249 0.202901829536925 0.632387016769835 GO:0008081 phosphoric diester hydrolase activity 3/336 87/18639 0.0344827586206897 1.91286945812808 0.207197358269059 0.632387016769835 GO:0005504 fatty acid binding 2/336 47/18639 0.0425531914893617 2.36056231003039 0.207687810530015 0.632387016769835 GO:0043495 protein-membrane adaptor activity 2/336 47/18639 0.0425531914893617 2.36056231003039 0.207687810530015 0.632387016769835 GO:0016298 lipase activity 4/336 130/18639 0.0307692307692308 1.70686813186813 0.207816431844786 0.632387016769835 GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity 1/336 13/18639 0.0769230769230769 4.26717032967033 0.210663202658267 0.632387016769835 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 1/336 13/18639 0.0769230769230769 4.26717032967033 0.210663202658267 0.632387016769835 GO:0005338 nucleotide-sugar transmembrane transporter activity 1/336 13/18639 0.0769230769230769 4.26717032967033 0.210663202658267 0.632387016769835 GO:0008035 high-density lipoprotein particle binding 1/336 13/18639 0.0769230769230769 4.26717032967033 0.210663202658267 0.632387016769835 GO:0031994 insulin-like growth factor I binding 1/336 13/18639 0.0769230769230769 4.26717032967033 0.210663202658267 0.632387016769835 GO:0035673 oligopeptide transmembrane transporter activity 1/336 13/18639 0.0769230769230769 4.26717032967033 0.210663202658267 0.632387016769835 GO:0043560 insulin receptor substrate binding 1/336 13/18639 0.0769230769230769 4.26717032967033 0.210663202658267 0.632387016769835 GO:0046975 histone H3K36 methyltransferase activity 1/336 13/18639 0.0769230769230769 4.26717032967033 0.210663202658267 0.632387016769835 GO:0140333 glycerophospholipid flippase activity 1/336 13/18639 0.0769230769230769 4.26717032967033 0.210663202658267 0.632387016769835 GO:0004197 cysteine-type endopeptidase activity 3/336 88/18639 0.0340909090909091 1.89113230519481 0.211872730498461 0.632387016769835 GO:0005004 GPI-linked ephrin receptor activity 2/336 49/18639 0.0408163265306122 2.26421282798834 0.220949940803318 0.632387016769835 GO:0005008 hepatocyte growth factor receptor activity 2/336 49/18639 0.0408163265306122 2.26421282798834 0.220949940803318 0.632387016769835 GO:0005009 insulin receptor activity 2/336 49/18639 0.0408163265306122 2.26421282798834 0.220949940803318 0.632387016769835 GO:0005011 macrophage colony-stimulating factor receptor activity 2/336 49/18639 0.0408163265306122 2.26421282798834 0.220949940803318 0.632387016769835 GO:0005018 platelet-derived growth factor alpha-receptor activity 2/336 49/18639 0.0408163265306122 2.26421282798834 0.220949940803318 0.632387016769835 GO:0005020 stem cell factor receptor activity 2/336 49/18639 0.0408163265306122 2.26421282798834 0.220949940803318 0.632387016769835 GO:0008288 boss receptor activity 2/336 49/18639 0.0408163265306122 2.26421282798834 0.220949940803318 0.632387016769835 GO:0036332 placental growth factor receptor activity 2/336 49/18639 0.0408163265306122 2.26421282798834 0.220949940803318 0.632387016769835 GO:0038062 protein tyrosine kinase collagen receptor activity 2/336 49/18639 0.0408163265306122 2.26421282798834 0.220949940803318 0.632387016769835 GO:0060175 brain-derived neurotrophic factor receptor activity 2/336 49/18639 0.0408163265306122 2.26421282798834 0.220949940803318 0.632387016769835 GO:0060590 ATPase regulator activity 2/336 49/18639 0.0408163265306122 2.26421282798834 0.220949940803318 0.632387016769835 GO:0019210 kinase inhibitor activity 3/336 90/18639 0.0333333333333333 1.84910714285714 0.221290906164254 0.632387016769835 GO:0004705 JUN kinase activity 1/336 14/18639 0.0714285714285714 3.96237244897959 0.224902285870273 0.632387016769835 GO:0008559 ABC-type xenobiotic transporter activity 1/336 14/18639 0.0714285714285714 3.96237244897959 0.224902285870273 0.632387016769835 GO:0030283 testosterone dehydrogenase [NAD(P)+] activity 1/336 14/18639 0.0714285714285714 3.96237244897959 0.224902285870273 0.632387016769835 GO:0043176 amine binding 1/336 14/18639 0.0714285714285714 3.96237244897959 0.224902285870273 0.632387016769835 GO:0071933 Arp2/3 complex binding 1/336 14/18639 0.0714285714285714 3.96237244897959 0.224902285870273 0.632387016769835 GO:1901612 cardiolipin binding 1/336 14/18639 0.0714285714285714 3.96237244897959 0.224902285870273 0.632387016769835 GO:0072341 modified amino acid binding 3/336 91/18639 0.032967032967033 1.82878728414443 0.226031468243833 0.632387016769835 GO:0005007 fibroblast growth factor receptor activity 2/336 50/18639 0.04 2.21892857142857 0.227607253121787 0.632387016769835 GO:0005017 platelet-derived growth factor receptor activity 2/336 50/18639 0.04 2.21892857142857 0.227607253121787 0.632387016769835 GO:0005019 platelet-derived growth factor beta-receptor activity 2/336 50/18639 0.04 2.21892857142857 0.227607253121787 0.632387016769835 GO:0005010 insulin-like growth factor receptor activity 2/336 51/18639 0.0392156862745098 2.17542016806723 0.234278371787184 0.632387016769835 GO:0005030 neurotrophin receptor activity 2/336 51/18639 0.0392156862745098 2.17542016806723 0.234278371787184 0.632387016769835 GO:0000287 magnesium ion binding 6/336 230/18639 0.0260869565217391 1.44712732919255 0.235958214646627 0.632387016769835 GO:0061135 endopeptidase regulator activity 5/336 184/18639 0.0271739130434783 1.50742430124224 0.238707820205778 0.632387016769835 GO:0004467 long-chain fatty acid-CoA ligase activity 1/336 15/18639 0.0666666666666667 3.69821428571429 0.238885256713096 0.632387016769835 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 1/336 15/18639 0.0666666666666667 3.69821428571429 0.238885256713096 0.632387016769835 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 1/336 15/18639 0.0666666666666667 3.69821428571429 0.238885256713096 0.632387016769835 GO:0005041 low-density lipoprotein particle receptor activity 1/336 15/18639 0.0666666666666667 3.69821428571429 0.238885256713096 0.632387016769835 GO:0015116 sulfate transmembrane transporter activity 1/336 15/18639 0.0666666666666667 3.69821428571429 0.238885256713096 0.632387016769835 GO:0015556 C4-dicarboxylate transmembrane transporter activity 1/336 15/18639 0.0666666666666667 3.69821428571429 0.238885256713096 0.632387016769835 GO:0016846 carbon-sulfur lyase activity 1/336 15/18639 0.0666666666666667 3.69821428571429 0.238885256713096 0.632387016769835 GO:0048531 beta-1,3-galactosyltransferase activity 1/336 15/18639 0.0666666666666667 3.69821428571429 0.238885256713096 0.632387016769835 GO:0061578 K63-linked deubiquitinase activity 1/336 15/18639 0.0666666666666667 3.69821428571429 0.238885256713096 0.632387016769835 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 2/336 52/18639 0.0384615384615385 2.13358516483517 0.240960644873075 0.632387016769835 GO:0030295 protein kinase activator activity 4/336 139/18639 0.0287769784172662 1.59635149023638 0.242257650542932 0.632387016769835 GO:0004867 serine-type endopeptidase inhibitor activity 3/336 95/18639 0.0315789473684211 1.75178571428571 0.245177937758189 0.632387016769835 GO:0005003 ephrin receptor activity 2/336 53/18639 0.0377358490566038 2.09332884097035 0.247651511030964 0.632387016769835 GO:0005005 transmembrane-ephrin receptor activity 2/336 53/18639 0.0377358490566038 2.09332884097035 0.247651511030964 0.632387016769835 GO:0038064 collagen receptor activity 2/336 53/18639 0.0377358490566038 2.09332884097035 0.247651511030964 0.632387016769835 GO:0003688 DNA replication origin binding 1/336 16/18639 0.0625 3.46707589285714 0.252616708267241 0.632387016769835 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 1/336 16/18639 0.0625 3.46707589285714 0.252616708267241 0.632387016769835 GO:0004707 MAP kinase activity 1/336 16/18639 0.0625 3.46707589285714 0.252616708267241 0.632387016769835 GO:0004708 MAP kinase kinase activity 1/336 16/18639 0.0625 3.46707589285714 0.252616708267241 0.632387016769835 GO:0005159 insulin-like growth factor receptor binding 1/336 16/18639 0.0625 3.46707589285714 0.252616708267241 0.632387016769835 GO:0005324 long-chain fatty acid transmembrane transporter activity 1/336 16/18639 0.0625 3.46707589285714 0.252616708267241 0.632387016769835 GO:0005521 lamin binding 1/336 16/18639 0.0625 3.46707589285714 0.252616708267241 0.632387016769835 GO:0015562 efflux transmembrane transporter activity 1/336 16/18639 0.0625 3.46707589285714 0.252616708267241 0.632387016769835 GO:0017070 U6 snRNA binding 1/336 16/18639 0.0625 3.46707589285714 0.252616708267241 0.632387016769835 GO:0061809 NAD+ nucleosidase activity, cyclic ADP-ribose generating 1/336 16/18639 0.0625 3.46707589285714 0.252616708267241 0.632387016769835 GO:0140327 flippase activity 1/336 16/18639 0.0625 3.46707589285714 0.252616708267241 0.632387016769835 GO:0140328 floppase activity 1/336 16/18639 0.0625 3.46707589285714 0.252616708267241 0.632387016769835 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 2/336 54/18639 0.037037037037037 2.05456349206349 0.254348497103019 0.632387016769835 GO:0051287 NAD binding 2/336 54/18639 0.037037037037037 2.05456349206349 0.254348497103019 0.632387016769835 GO:0140313 molecular sequestering activity 2/336 55/18639 0.0363636363636364 2.01720779220779 0.261049215791004 0.633407986810649 GO:0015291 secondary active transmembrane transporter activity 7/336 287/18639 0.024390243902439 1.35300522648084 0.261481087177079 0.633407986810649 GO:0019207 kinase regulator activity 7/336 287/18639 0.024390243902439 1.35300522648084 0.261481087177079 0.633407986810649 GO:0019903 protein phosphatase binding 4/336 144/18639 0.0277777777777778 1.54092261904762 0.261924937511513 0.633407986810649 GO:0004029 aldehyde dehydrogenase (NAD+) activity 1/336 17/18639 0.0588235294117647 3.26313025210084 0.266101151483813 0.633407986810649 GO:0008569 minus-end-directed microtubule motor activity 1/336 17/18639 0.0588235294117647 3.26313025210084 0.266101151483813 0.633407986810649 GO:0015278 intracellularly gated calcium channel activity 1/336 17/18639 0.0588235294117647 3.26313025210084 0.266101151483813 0.633407986810649 GO:0017110 nucleoside diphosphate phosphatase activity 1/336 17/18639 0.0588235294117647 3.26313025210084 0.266101151483813 0.633407986810649 GO:0032977 membrane insertase activity 1/336 17/18639 0.0588235294117647 3.26313025210084 0.266101151483813 0.633407986810649 GO:0038191 neuropilin binding 1/336 17/18639 0.0588235294117647 3.26313025210084 0.266101151483813 0.633407986810649 GO:0045236 CXCR chemokine receptor binding 1/336 17/18639 0.0588235294117647 3.26313025210084 0.266101151483813 0.633407986810649 GO:0051787 misfolded protein binding 1/336 17/18639 0.0588235294117647 3.26313025210084 0.266101151483813 0.633407986810649 GO:0070403 NAD+ binding 1/336 17/18639 0.0588235294117647 3.26313025210084 0.266101151483813 0.633407986810649 GO:0019209 kinase activator activity 4/336 148/18639 0.027027027027027 1.49927606177606 0.277871977661301 0.633563198209154 GO:0015171 amino acid transmembrane transporter activity 3/336 102/18639 0.0294117647058824 1.63156512605042 0.279231238858371 0.633563198209154 GO:0000400 four-way junction DNA binding 1/336 18/18639 0.0555555555555556 3.08184523809524 0.279343016648749 0.633563198209154 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity 1/336 18/18639 0.0555555555555556 3.08184523809524 0.279343016648749 0.633563198209154 GO:0004706 JUN kinase kinase kinase activity 1/336 18/18639 0.0555555555555556 3.08184523809524 0.279343016648749 0.633563198209154 GO:0008525 phosphatidylcholine transporter activity 1/336 18/18639 0.0555555555555556 3.08184523809524 0.279343016648749 0.633563198209154 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 1/336 18/18639 0.0555555555555556 3.08184523809524 0.279343016648749 0.633563198209154 GO:0017075 syntaxin-1 binding 1/336 18/18639 0.0555555555555556 3.08184523809524 0.279343016648749 0.633563198209154 GO:0022851 GABA-gated chloride ion channel activity 1/336 18/18639 0.0555555555555556 3.08184523809524 0.279343016648749 0.633563198209154 GO:0030228 lipoprotein particle receptor activity 1/336 18/18639 0.0555555555555556 3.08184523809524 0.279343016648749 0.633563198209154 GO:0034185 apolipoprotein binding 1/336 18/18639 0.0555555555555556 3.08184523809524 0.279343016648749 0.633563198209154 GO:0070064 proline-rich region binding 1/336 18/18639 0.0555555555555556 3.08184523809524 0.279343016648749 0.633563198209154 GO:1901611 phosphatidylglycerol binding 1/336 18/18639 0.0555555555555556 3.08184523809524 0.279343016648749 0.633563198209154 GO:0042393 histone binding 6/336 247/18639 0.0242914979757085 1.34752747252747 0.287489196981558 0.633563198209154 GO:0001786 phosphatidylserine binding 2/336 59/18639 0.0338983050847458 1.88044794188862 0.287844549858455 0.633563198209154 GO:0004879 nuclear receptor activity 2/336 59/18639 0.0338983050847458 1.88044794188862 0.287844549858455 0.633563198209154 GO:0036002 pre-mRNA binding 2/336 59/18639 0.0338983050847458 1.88044794188862 0.287844549858455 0.633563198209154 GO:0003756 protein disulfide isomerase activity 1/336 19/18639 0.0526315789473684 2.91964285714286 0.292346654821028 0.633563198209154 GO:0004303 estradiol 17-beta-dehydrogenase [NAD(P)+] activity 1/336 19/18639 0.0526315789473684 2.91964285714286 0.292346654821028 0.633563198209154 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 1/336 19/18639 0.0526315789473684 2.91964285714286 0.292346654821028 0.633563198209154 GO:0004890 GABA-A receptor activity 1/336 19/18639 0.0526315789473684 2.91964285714286 0.292346654821028 0.633563198209154 GO:0008381 mechanosensitive monoatomic ion channel activity 1/336 19/18639 0.0526315789473684 2.91964285714286 0.292346654821028 0.633563198209154 GO:0015245 fatty acid transmembrane transporter activity 1/336 19/18639 0.0526315789473684 2.91964285714286 0.292346654821028 0.633563198209154 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 1/336 19/18639 0.0526315789473684 2.91964285714286 0.292346654821028 0.633563198209154 GO:0030506 ankyrin binding 1/336 19/18639 0.0526315789473684 2.91964285714286 0.292346654821028 0.633563198209154 GO:0031420 alkali metal ion binding 1/336 19/18639 0.0526315789473684 2.91964285714286 0.292346654821028 0.633563198209154 GO:0046624 sphingolipid transporter activity 1/336 19/18639 0.0526315789473684 2.91964285714286 0.292346654821028 0.633563198209154 GO:0050145 nucleoside monophosphate kinase activity 1/336 19/18639 0.0526315789473684 2.91964285714286 0.292346654821028 0.633563198209154 GO:0097001 ceramide binding 1/336 19/18639 0.0526315789473684 2.91964285714286 0.292346654821028 0.633563198209154 GO:1990380 K48-linked deubiquitinase activity 1/336 19/18639 0.0526315789473684 2.91964285714286 0.292346654821028 0.633563198209154 GO:0098531 ligand-modulated transcription factor activity 2/336 60/18639 0.0333333333333333 1.84910714285714 0.294530970890007 0.635365791448283 GO:0046873 metal ion transmembrane transporter activity 10/336 450/18639 0.0222222222222222 1.2327380952381 0.294928748922963 0.635365791448283 GO:0015026 coreceptor activity 2/336 61/18639 0.0327868852459016 1.81879391100703 0.301208480036237 0.64207090519448 GO:0019888 protein phosphatase regulator activity 3/336 107/18639 0.0280373831775701 1.55532376502003 0.303821732721092 0.64207090519448 GO:0000339 RNA cap binding 1/336 20/18639 0.05 2.77366071428571 0.305116339245311 0.64207090519448 GO:0003899 DNA-directed 5'-3' RNA polymerase activity 1/336 20/18639 0.05 2.77366071428571 0.305116339245311 0.64207090519448 GO:0015095 magnesium ion transmembrane transporter activity 1/336 20/18639 0.05 2.77366071428571 0.305116339245311 0.64207090519448 GO:0016004 phospholipase activator activity 1/336 20/18639 0.05 2.77366071428571 0.305116339245311 0.64207090519448 GO:0016408 C-acyltransferase activity 1/336 20/18639 0.05 2.77366071428571 0.305116339245311 0.64207090519448 GO:0140939 histone H4 methyltransferase activity 1/336 20/18639 0.05 2.77366071428571 0.305116339245311 0.64207090519448 GO:0005496 steroid binding 3/336 108/18639 0.0277777777777778 1.54092261904762 0.308754313615177 0.647848646487336 GO:0140375 immune receptor activity 4/336 156/18639 0.0256410256410256 1.42239010989011 0.310186165794998 0.648977395870804 GO:0005123 death receptor binding 1/336 21/18639 0.0476190476190476 2.64158163265306 0.31765626673946 0.658909856150995 GO:0009931 calcium-dependent protein serine/threonine kinase activity 1/336 21/18639 0.0476190476190476 2.64158163265306 0.31765626673946 0.658909856150995 GO:0070182 DNA polymerase binding 1/336 21/18639 0.0476190476190476 2.64158163265306 0.31765626673946 0.658909856150995 GO:0038024 cargo receptor activity 2/336 65/18639 0.0307692307692308 1.70686813186813 0.327793481262733 0.668507280411149 GO:0008093 cytoskeletal anchor activity 1/336 22/18639 0.0454545454545455 2.52150974025974 0.329970559057408 0.668507280411149 GO:0030021 extracellular matrix structural constituent conferring compression resistance 1/336 22/18639 0.0454545454545455 2.52150974025974 0.329970559057408 0.668507280411149 GO:0034062 5'-3' RNA polymerase activity 1/336 22/18639 0.0454545454545455 2.52150974025974 0.329970559057408 0.668507280411149 GO:0061133 endopeptidase activator activity 1/336 22/18639 0.0454545454545455 2.52150974025974 0.329970559057408 0.668507280411149 GO:0097747 RNA polymerase activity 1/336 22/18639 0.0454545454545455 2.52150974025974 0.329970559057408 0.668507280411149 GO:0140035 ubiquitin-like protein reader activity 1/336 22/18639 0.0454545454545455 2.52150974025974 0.329970559057408 0.668507280411149 GO:0140517 protein-RNA adaptor activity 1/336 22/18639 0.0454545454545455 2.52150974025974 0.329970559057408 0.668507280411149 GO:0004866 endopeptidase inhibitor activity 4/336 161/18639 0.0248447204968944 1.3782165039929 0.33057040450083 0.668507280411149 GO:0008083 growth factor activity 4/336 162/18639 0.0246913580246914 1.36970899470899 0.334657531505253 0.669470540663966 GO:0016887 ATP hydrolysis activity 9/336 417/18639 0.0215827338129496 1.19726361767729 0.338981702622733 0.669470540663966 GO:0005283 amino acid:sodium symporter activity 1/336 23/18639 0.0434782608695652 2.41187888198758 0.342063264227774 0.669470540663966 GO:0008171 O-methyltransferase activity 1/336 23/18639 0.0434782608695652 2.41187888198758 0.342063264227774 0.669470540663966 GO:0016917 GABA receptor activity 1/336 23/18639 0.0434782608695652 2.41187888198758 0.342063264227774 0.669470540663966 GO:0043274 phospholipase binding 1/336 23/18639 0.0434782608695652 2.41187888198758 0.342063264227774 0.669470540663966 GO:0015081 sodium ion transmembrane transporter activity 4/336 164/18639 0.024390243902439 1.35300522648084 0.342838183088282 0.669470540663966 GO:0001221 transcription coregulator binding 3/336 115/18639 0.0260869565217391 1.44712732919255 0.343312565162789 0.669470540663966 GO:0035401 histone H3Y41 kinase activity 3/336 115/18639 0.0260869565217391 1.44712732919255 0.343312565162789 0.669470540663966 GO:0140801 histone H2AXY142 kinase activity 3/336 115/18639 0.0260869565217391 1.44712732919255 0.343312565162789 0.669470540663966 GO:0005548 phospholipid transporter activity 2/336 68/18639 0.0294117647058824 1.63156512605042 0.34755482895982 0.669470540663966 GO:0015294 solute:monoatomic cation symporter activity 3/336 116/18639 0.0258620689655172 1.43465209359606 0.348244004454632 0.669470540663966 GO:0019208 phosphatase regulator activity 3/336 117/18639 0.0256410256410256 1.42239010989011 0.353171749175684 0.669470540663966 GO:1990782 protein tyrosine kinase binding 3/336 117/18639 0.0256410256410256 1.42239010989011 0.353171749175684 0.669470540663966 GO:0005315 phosphate transmembrane transporter activity 1/336 24/18639 0.0416666666666667 2.31138392857143 0.353938357868699 0.669470540663966 GO:0005540 hyaluronic acid binding 1/336 24/18639 0.0416666666666667 2.31138392857143 0.353938357868699 0.669470540663966 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 1/336 24/18639 0.0416666666666667 2.31138392857143 0.353938357868699 0.669470540663966 GO:0030215 semaphorin receptor binding 1/336 24/18639 0.0416666666666667 2.31138392857143 0.353938357868699 0.669470540663966 GO:0042625 ATPase-coupled ion transmembrane transporter activity 1/336 24/18639 0.0416666666666667 2.31138392857143 0.353938357868699 0.669470540663966 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 1/336 24/18639 0.0416666666666667 2.31138392857143 0.353938357868699 0.669470540663966 GO:0046961 proton-transporting ATPase activity, rotational mechanism 1/336 24/18639 0.0416666666666667 2.31138392857143 0.353938357868699 0.669470540663966 GO:0050431 transforming growth factor beta binding 1/336 24/18639 0.0416666666666667 2.31138392857143 0.353938357868699 0.669470540663966 GO:0060229 lipase activator activity 1/336 24/18639 0.0416666666666667 2.31138392857143 0.353938357868699 0.669470540663966 GO:0070840 dynein complex binding 1/336 24/18639 0.0416666666666667 2.31138392857143 0.353938357868699 0.669470540663966 GO:0002039 p53 binding 2/336 69/18639 0.0289855072463768 1.60791925465839 0.354100120681767 0.669470540663966 GO:0016782 transferase activity, transferring sulphur-containing groups 2/336 70/18639 0.0285714285714286 1.58494897959184 0.360622211854324 0.673668564700415 GO:0030414 peptidase inhibitor activity 4/336 169/18639 0.0236686390532544 1.31297548605241 0.363305268980048 0.673668564700415 GO:0000030 mannosyltransferase activity 1/336 25/18639 0.04 2.21892857142857 0.365599744479289 0.673668564700415 GO:0001848 complement binding 1/336 25/18639 0.04 2.21892857142857 0.365599744479289 0.673668564700415 GO:0003707 nuclear steroid receptor activity 1/336 25/18639 0.04 2.21892857142857 0.365599744479289 0.673668564700415 GO:0015662 P-type ion transporter activity 1/336 25/18639 0.04 2.21892857142857 0.365599744479289 0.673668564700415 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 1/336 25/18639 0.04 2.21892857142857 0.365599744479289 0.673668564700415 GO:0019706 protein-cysteine S-palmitoyltransferase activity 1/336 25/18639 0.04 2.21892857142857 0.365599744479289 0.673668564700415 GO:0019707 protein-cysteine S-acyltransferase activity 1/336 25/18639 0.04 2.21892857142857 0.365599744479289 0.673668564700415 GO:0140358 P-type transmembrane transporter activity 1/336 25/18639 0.04 2.21892857142857 0.365599744479289 0.673668564700415 GO:0004435 phosphatidylinositol phospholipase C activity 1/336 26/18639 0.0384615384615385 2.13358516483517 0.377051258708093 0.682574769856897 GO:0005227 calcium-activated cation channel activity 1/336 26/18639 0.0384615384615385 2.13358516483517 0.377051258708093 0.682574769856897 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 1/336 26/18639 0.0384615384615385 2.13358516483517 0.377051258708093 0.682574769856897 GO:0008143 poly(A) binding 1/336 26/18639 0.0384615384615385 2.13358516483517 0.377051258708093 0.682574769856897 GO:0034237 protein kinase A regulatory subunit binding 1/336 26/18639 0.0384615384615385 2.13358516483517 0.377051258708093 0.682574769856897 GO:0097602 cullin family protein binding 1/336 26/18639 0.0384615384615385 2.13358516483517 0.377051258708093 0.682574769856897 GO:0120014 phospholipid transfer activity 1/336 26/18639 0.0384615384615385 2.13358516483517 0.377051258708093 0.682574769856897 GO:0004521 RNA endonuclease activity 2/336 73/18639 0.0273972602739726 1.51981409001957 0.380036657041962 0.682574769856897 GO:0061134 peptidase regulator activity 5/336 226/18639 0.0221238938053097 1.22728350189633 0.385816417257775 0.682574769856897 GO:0035064 methylated histone binding 2/336 74/18639 0.027027027027027 1.49927606177606 0.38645358361724 0.682574769856897 GO:0005267 potassium channel activity 3/336 124/18639 0.0241935483870968 1.34209389400922 0.387502160096763 0.682574769856897 GO:0003735 structural constituent of ribosome 4/336 175/18639 0.0228571428571429 1.26795918367347 0.38783062051903 0.682574769856897 GO:0005044 scavenger receptor activity 1/336 27/18639 0.037037037037037 2.05456349206349 0.388296666599034 0.682574769856897 GO:0005104 fibroblast growth factor receptor binding 1/336 27/18639 0.037037037037037 2.05456349206349 0.388296666599034 0.682574769856897 GO:0005385 zinc ion transmembrane transporter activity 1/336 27/18639 0.037037037037037 2.05456349206349 0.388296666599034 0.682574769856897 GO:0008266 poly(U) RNA binding 1/336 27/18639 0.037037037037037 2.05456349206349 0.388296666599034 0.682574769856897 GO:0008320 protein transmembrane transporter activity 1/336 27/18639 0.037037037037037 2.05456349206349 0.388296666599034 0.682574769856897 GO:0035255 ionotropic glutamate receptor binding 1/336 27/18639 0.037037037037037 2.05456349206349 0.388296666599034 0.682574769856897 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 1/336 27/18639 0.037037037037037 2.05456349206349 0.388296666599034 0.682574769856897 GO:0003725 double-stranded RNA binding 2/336 75/18639 0.0266666666666667 1.47928571428571 0.392841385926896 0.684982974129141 GO:0019003 GDP binding 2/336 75/18639 0.0266666666666667 1.47928571428571 0.392841385926896 0.684982974129141 GO:0051536 iron-sulfur cluster binding 2/336 76/18639 0.0263157894736842 1.45982142857143 0.399199028667478 0.684982974129141 GO:0140034 methylation-dependent protein binding 2/336 76/18639 0.0263157894736842 1.45982142857143 0.399199028667478 0.684982974129141 GO:0045499 chemorepellent activity 1/336 28/18639 0.0357142857142857 1.9811862244898 0.39933966681517 0.684982974129141 GO:0046625 sphingolipid binding 1/336 28/18639 0.0357142857142857 1.9811862244898 0.39933966681517 0.684982974129141 GO:0046966 nuclear thyroid hormone receptor binding 1/336 28/18639 0.0357142857142857 1.9811862244898 0.39933966681517 0.684982974129141 GO:0051959 dynein light intermediate chain binding 1/336 28/18639 0.0357142857142857 1.9811862244898 0.39933966681517 0.684982974129141 GO:0097718 disordered domain specific binding 1/336 28/18639 0.0357142857142857 1.9811862244898 0.39933966681517 0.684982974129141 GO:0051540 metal cluster binding 2/336 77/18639 0.025974025974026 1.44086270871985 0.405525523079929 0.684982974129141 GO:0003785 actin monomer binding 1/336 29/18639 0.0344827586206897 1.91286945812808 0.410183891840698 0.684982974129141 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 1/336 29/18639 0.0344827586206897 1.91286945812808 0.410183891840698 0.684982974129141 GO:0005416 amino acid:monoatomic cation symporter activity 1/336 29/18639 0.0344827586206897 1.91286945812808 0.410183891840698 0.684982974129141 GO:0016417 S-acyltransferase activity 1/336 29/18639 0.0344827586206897 1.91286945812808 0.410183891840698 0.684982974129141 GO:0035250 UDP-galactosyltransferase activity 1/336 29/18639 0.0344827586206897 1.91286945812808 0.410183891840698 0.684982974129141 GO:0043236 laminin binding 1/336 29/18639 0.0344827586206897 1.91286945812808 0.410183891840698 0.684982974129141 GO:0051861 glycolipid binding 1/336 29/18639 0.0344827586206897 1.91286945812808 0.410183891840698 0.684982974129141 GO:0097472 cyclin-dependent protein kinase activity 1/336 29/18639 0.0344827586206897 1.91286945812808 0.410183891840698 0.684982974129141 GO:0099604 ligand-gated calcium channel activity 1/336 29/18639 0.0344827586206897 1.91286945812808 0.410183891840698 0.684982974129141 GO:0035591 signaling adaptor activity 3/336 129/18639 0.0232558139534884 1.29007475083056 0.411761533895399 0.684982974129141 GO:0005261 monoatomic cation channel activity 7/336 341/18639 0.0205278592375367 1.13874633431085 0.417713217369608 0.684982974129141 GO:0046332 SMAD binding 2/336 79/18639 0.0253164556962025 1.40438517179024 0.418081336642025 0.684982974129141 GO:0001965 G-protein alpha-subunit binding 1/336 30/18639 0.0333333333333333 1.84910714285714 0.420832909161575 0.684982974129141 GO:0005217 intracellularly ligand-gated monoatomic ion channel activity 1/336 30/18639 0.0333333333333333 1.84910714285714 0.420832909161575 0.684982974129141 GO:0008187 poly-pyrimidine tract binding 1/336 30/18639 0.0333333333333333 1.84910714285714 0.420832909161575 0.684982974129141 GO:0022839 monoatomic ion-gated channel activity 1/336 30/18639 0.0333333333333333 1.84910714285714 0.420832909161575 0.684982974129141 GO:0031624 ubiquitin conjugating enzyme binding 1/336 30/18639 0.0333333333333333 1.84910714285714 0.420832909161575 0.684982974129141 GO:0000049 tRNA binding 2/336 80/18639 0.025 1.38683035714286 0.424308899162988 0.684982974129141 GO:0048306 calcium-dependent protein binding 2/336 80/18639 0.025 1.38683035714286 0.424308899162988 0.684982974129141 GO:0005179 hormone activity 3/336 132/18639 0.0227272727272727 1.26075487012987 0.426175532130235 0.684982974129141 GO:0033192 calmodulin-dependent protein phosphatase activity 2/336 81/18639 0.0246913580246914 1.36970899470899 0.430501797593353 0.684982974129141 GO:0140791 histone H2AXS140 phosphatase activity 2/336 81/18639 0.0246913580246914 1.36970899470899 0.430501797593353 0.684982974129141 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 2/336 81/18639 0.0246913580246914 1.36970899470899 0.430501797593353 0.684982974129141 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 2/336 81/18639 0.0246913580246914 1.36970899470899 0.430501797593353 0.684982974129141 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 2/336 81/18639 0.0246913580246914 1.36970899470899 0.430501797593353 0.684982974129141 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 2/336 81/18639 0.0246913580246914 1.36970899470899 0.430501797593353 0.684982974129141 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 2/336 81/18639 0.0246913580246914 1.36970899470899 0.430501797593353 0.684982974129141 GO:1990439 MAP kinase serine/threonine phosphatase activity 2/336 81/18639 0.0246913580246914 1.36970899470899 0.430501797593353 0.684982974129141 GO:0005452 solute:inorganic anion antiporter activity 1/336 31/18639 0.032258064516129 1.78945852534562 0.431290222425142 0.684982974129141 GO:0017147 Wnt-protein binding 1/336 31/18639 0.032258064516129 1.78945852534562 0.431290222425142 0.684982974129141 GO:0047499 calcium-independent phospholipase A2 activity 1/336 31/18639 0.032258064516129 1.78945852534562 0.431290222425142 0.684982974129141 GO:0051087 protein-folding chaperone binding 3/336 134/18639 0.0223880597014925 1.24193763326226 0.435716640744391 0.684982974129141 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 2/336 82/18639 0.024390243902439 1.35300522648084 0.436659256546766 0.684982974129141 GO:0033549 MAP kinase phosphatase activity 2/336 82/18639 0.024390243902439 1.35300522648084 0.436659256546766 0.684982974129141 GO:0015297 antiporter activity 3/336 135/18639 0.0222222222222222 1.2327380952381 0.44046518036975 0.684982974129141 GO:0008378 galactosyltransferase activity 1/336 32/18639 0.03125 1.73353794642857 0.441559272579116 0.684982974129141 GO:0015106 bicarbonate transmembrane transporter activity 1/336 32/18639 0.03125 1.73353794642857 0.441559272579116 0.684982974129141 GO:0022884 macromolecule transmembrane transporter activity 1/336 32/18639 0.03125 1.73353794642857 0.441559272579116 0.684982974129141 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/336 32/18639 0.03125 1.73353794642857 0.441559272579116 0.684982974129141 GO:0042910 xenobiotic transmembrane transporter activity 1/336 32/18639 0.03125 1.73353794642857 0.441559272579116 0.684982974129141 GO:0043425 bHLH transcription factor binding 1/336 32/18639 0.03125 1.73353794642857 0.441559272579116 0.684982974129141 GO:0047498 calcium-dependent phospholipase A2 activity 1/336 32/18639 0.03125 1.73353794642857 0.441559272579116 0.684982974129141 GO:0070717 poly-purine tract binding 1/336 32/18639 0.03125 1.73353794642857 0.441559272579116 0.684982974129141 GO:0071813 lipoprotein particle binding 1/336 32/18639 0.03125 1.73353794642857 0.441559272579116 0.684982974129141 GO:0071814 protein-lipid complex binding 1/336 32/18639 0.03125 1.73353794642857 0.441559272579116 0.684982974129141 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 2/336 83/18639 0.0240963855421687 1.33670395869191 0.442780539660229 0.685412946254427 GO:0140789 histone phosphatase activity 3/336 136/18639 0.0220588235294118 1.22367384453782 0.445198386328418 0.685968905244723 GO:0019902 phosphatase binding 4/336 190/18639 0.0210526315789474 1.16785714285714 0.448416162843499 0.685968905244723 GO:0017018 myosin phosphatase activity 2/336 84/18639 0.0238095238095238 1.32079081632653 0.448864948446659 0.685968905244723 GO:0051117 ATPase binding 2/336 84/18639 0.0238095238095238 1.32079081632653 0.448864948446659 0.685968905244723 GO:0016922 nuclear receptor binding 3/336 137/18639 0.0218978102189781 1.21474191866528 0.449915781857091 0.685968905244723 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 1/336 33/18639 0.0303030303030303 1.68100649350649 0.451643438990327 0.685968905244723 GO:0030296 protein tyrosine kinase activator activity 1/336 33/18639 0.0303030303030303 1.68100649350649 0.451643438990327 0.685968905244723 GO:0071889 14-3-3 protein binding 1/336 33/18639 0.0303030303030303 1.68100649350649 0.451643438990327 0.685968905244723 GO:0140311 protein sequestering activity 1/336 33/18639 0.0303030303030303 1.68100649350649 0.451643438990327 0.685968905244723 GO:0008376 acetylgalactosaminyltransferase activity 1/336 34/18639 0.0294117647058824 1.63156512605042 0.461546040543549 0.695191754013728 GO:0015035 protein-disulfide reductase activity 1/336 34/18639 0.0294117647058824 1.63156512605042 0.461546040543549 0.695191754013728 GO:0016831 carboxy-lyase activity 1/336 34/18639 0.0294117647058824 1.63156512605042 0.461546040543549 0.695191754013728 GO:0090482 vitamin transmembrane transporter activity 1/336 34/18639 0.0294117647058824 1.63156512605042 0.461546040543549 0.695191754013728 GO:0004623 phospholipase A2 activity 1/336 35/18639 0.0285714285714286 1.58494897959184 0.47127033672078 0.705201975369937 GO:0005154 epidermal growth factor receptor binding 1/336 35/18639 0.0285714285714286 1.58494897959184 0.47127033672078 0.705201975369937 GO:0016229 steroid dehydrogenase activity 1/336 35/18639 0.0285714285714286 1.58494897959184 0.47127033672078 0.705201975369937 GO:0106310 protein serine kinase activity 7/336 361/18639 0.0193905817174515 1.07565789473684 0.476165551699167 0.705201975369937 GO:0003727 single-stranded RNA binding 2/336 89/18639 0.0224719101123595 1.24658908507223 0.478711943065181 0.705201975369937 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 2/336 89/18639 0.0224719101123595 1.24658908507223 0.478711943065181 0.705201975369937 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 2/336 89/18639 0.0224719101123595 1.24658908507223 0.478711943065181 0.705201975369937 GO:0004190 aspartic-type endopeptidase activity 1/336 36/18639 0.0277777777777778 1.54092261904762 0.48081952866132 0.705201975369937 GO:0004869 cysteine-type endopeptidase inhibitor activity 1/336 36/18639 0.0277777777777778 1.54092261904762 0.48081952866132 0.705201975369937 GO:0005484 SNAP receptor activity 1/336 36/18639 0.0277777777777778 1.54092261904762 0.48081952866132 0.705201975369937 GO:0016409 palmitoyltransferase activity 1/336 36/18639 0.0277777777777778 1.54092261904762 0.48081952866132 0.705201975369937 GO:0044390 ubiquitin-like protein conjugating enzyme binding 1/336 36/18639 0.0277777777777778 1.54092261904762 0.48081952866132 0.705201975369937 GO:0045505 dynein intermediate chain binding 1/336 36/18639 0.0277777777777778 1.54092261904762 0.48081952866132 0.705201975369937 GO:0042578 phosphoric ester hydrolase activity 7/336 363/18639 0.0192837465564738 1.06973140495868 0.481939866701223 0.705420046824774 GO:0140793 histone H2AXY142 phosphatase activity 2/336 90/18639 0.0222222222222222 1.2327380952381 0.484562421176565 0.707831625300174 GO:0022829 wide pore channel activity 1/336 37/18639 0.027027027027027 1.49927606177606 0.490196760202996 0.71094260394127 GO:0042805 actinin binding 1/336 37/18639 0.027027027027027 1.49927606177606 0.490196760202996 0.71094260394127 GO:0070001 aspartic-type peptidase activity 1/336 37/18639 0.027027027027027 1.49927606177606 0.490196760202996 0.71094260394127 GO:0003713 transcription coactivator activity 5/336 256/18639 0.01953125 1.08346121651786 0.491372200695137 0.71094260394127 GO:0015293 symporter activity 3/336 146/18639 0.0205479452054795 1.13986056751468 0.491588412091622 0.71094260394127 GO:0015085 calcium ion transmembrane transporter activity 3/336 147/18639 0.0204081632653061 1.13210641399417 0.49612421932368 0.716075910992032 GO:0005109 frizzled binding 1/336 38/18639 0.0263157894736842 1.45982142857143 0.499405118904845 0.717956665989935 GO:0042887 amide transmembrane transporter activity 1/336 38/18639 0.0263157894736842 1.45982142857143 0.499405118904845 0.717956665989935 GO:0008509 monoatomic anion transmembrane transporter activity 3/336 149/18639 0.0201342281879195 1.11691035474593 0.505134769926095 0.724758582937441 GO:0042562 hormone binding 2/336 94/18639 0.0212765957446809 1.1802811550152 0.507552203724398 0.725212150293652 GO:0016776 phosphotransferase activity, phosphate group as acceptor 1/336 39/18639 0.0256410256410256 1.42239010989011 0.50844763705161 0.725212150293652 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 1/336 39/18639 0.0256410256410256 1.42239010989011 0.50844763705161 0.725212150293652 GO:0022836 gated channel activity 6/336 318/18639 0.0188679245283019 1.04666442048518 0.512606852797491 0.728383346337757 GO:0005516 calmodulin binding 4/336 207/18639 0.0193236714975845 1.07194616977226 0.514623396883441 0.728383346337757 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 1/336 40/18639 0.025 1.38683035714286 0.517327292640355 0.728383346337757 GO:0030331 nuclear estrogen receptor binding 1/336 40/18639 0.025 1.38683035714286 0.517327292640355 0.728383346337757 GO:0050997 quaternary ammonium group binding 1/336 40/18639 0.025 1.38683035714286 0.517327292640355 0.728383346337757 GO:0071949 FAD binding 1/336 40/18639 0.025 1.38683035714286 0.517327292640355 0.728383346337757 GO:0004896 cytokine receptor activity 2/336 96/18639 0.0208333333333333 1.15569196428571 0.518794435866626 0.728383346337757 GO:0016407 acetyltransferase activity 2/336 96/18639 0.0208333333333333 1.15569196428571 0.518794435866626 0.728383346337757 GO:0140297 DNA-binding transcription factor binding 9/336 488/18639 0.0184426229508197 1.02307157494145 0.519700514329143 0.728383346337757 GO:0004674 protein serine/threonine kinase activity 8/336 433/18639 0.0184757505773672 1.0249092708677 0.521966901595914 0.729041332983937 GO:0004518 nuclease activity 4/336 209/18639 0.0191387559808612 1.06168831168831 0.522178365222655 0.729041332983937 GO:0005525 GTP binding 7/336 378/18639 0.0185185185185185 1.02728174603175 0.524627452304062 0.730229693142935 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 1/336 41/18639 0.024390243902439 1.35300522648084 0.526047010349524 0.730229693142935 GO:0140318 protein transporter activity 1/336 41/18639 0.024390243902439 1.35300522648084 0.526047010349524 0.730229693142935 GO:0004725 protein tyrosine phosphatase activity 2/336 98/18639 0.0204081632653061 1.13210641399417 0.529864768828669 0.734125614827507 GO:0004520 DNA endonuclease activity 1/336 42/18639 0.0238095238095238 1.32079081632653 0.534609662490752 0.736483140357279 GO:0031492 nucleosomal DNA binding 1/336 42/18639 0.0238095238095238 1.32079081632653 0.534609662490752 0.736483140357279 GO:0035198 miRNA binding 1/336 42/18639 0.0238095238095238 1.32079081632653 0.534609662490752 0.736483140357279 GO:0043130 ubiquitin binding 2/336 100/18639 0.02 1.10946428571429 0.540761105013467 0.741035937554795 GO:0005543 phospholipid binding 9/336 497/18639 0.0181086519114688 1.00454512791032 0.541827834731943 0.741035937554795 GO:0004712 protein serine/threonine/tyrosine kinase activity 1/336 43/18639 0.0232558139534884 1.29007475083056 0.543018069943734 0.741035937554795 GO:0005245 voltage-gated calcium channel activity 1/336 43/18639 0.0232558139534884 1.29007475083056 0.543018069943734 0.741035937554795 GO:0008375 acetylglucosaminyltransferase activity 1/336 43/18639 0.0232558139534884 1.29007475083056 0.543018069943734 0.741035937554795 GO:0001223 transcription coactivator binding 1/336 44/18639 0.0227272727272727 1.26075487012987 0.551275003074456 0.749211745893834 GO:0016790 thiolester hydrolase activity 1/336 44/18639 0.0227272727272727 1.26075487012987 0.551275003074456 0.749211745893834 GO:0015079 potassium ion transmembrane transporter activity 3/336 160/18639 0.01875 1.04012276785714 0.553137046555227 0.749211745893834 GO:0099106 ion channel regulator activity 3/336 160/18639 0.01875 1.04012276785714 0.553137046555227 0.749211745893834 GO:0004722 protein serine/threonine phosphatase activity 2/336 103/18639 0.0194174757281553 1.07714979195562 0.556775676293227 0.750669483538854 GO:0005253 monoatomic anion channel activity 2/336 103/18639 0.0194174757281553 1.07714979195562 0.556775676293227 0.750669483538854 GO:0008009 chemokine activity 1/336 45/18639 0.0222222222222222 1.2327380952381 0.55938318263708 0.750669483538854 GO:0046915 transition metal ion transmembrane transporter activity 1/336 45/18639 0.0222222222222222 1.2327380952381 0.55938318263708 0.750669483538854 GO:0140303 intramembrane lipid transporter activity 1/336 45/18639 0.0222222222222222 1.2327380952381 0.55938318263708 0.750669483538854 GO:0005216 monoatomic ion channel activity 8/336 448/18639 0.0178571428571429 0.990593112244898 0.560744790726998 0.751108335918451 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 1/336 46/18639 0.0217391304347826 1.20593944099379 0.567345280659772 0.758550043755054 GO:0015103 inorganic anion transmembrane transporter activity 3/336 165/18639 0.0181818181818182 1.0086038961039 0.57402531808548 0.761987238822118 GO:0001784 phosphotyrosine residue binding 1/336 47/18639 0.0212765957446809 1.1802811550152 0.575163921314767 0.761987238822118 GO:0099095 ligand-gated monoatomic anion channel activity 1/336 47/18639 0.0212765957446809 1.1802811550152 0.575163921314767 0.761987238822118 GO:0140359 ABC-type transporter activity 1/336 47/18639 0.0212765957446809 1.1802811550152 0.575163921314767 0.761987238822118 GO:0140938 histone H3 methyltransferase activity 1/336 47/18639 0.0212765957446809 1.1802811550152 0.575163921314767 0.761987238822118 GO:0016879 ligase activity, forming carbon-nitrogen bonds 1/336 48/18639 0.0208333333333333 1.15569196428571 0.582841681772934 0.770352826663997 GO:0019001 guanyl nucleotide binding 7/336 400/18639 0.0175 0.97078125 0.58466171830835 0.770352826663997 GO:0032561 guanyl ribonucleotide binding 7/336 400/18639 0.0175 0.97078125 0.58466171830835 0.770352826663997 GO:0016247 channel regulator activity 3/336 168/18639 0.0178571428571429 0.990593112244898 0.586263606719511 0.771064091446314 GO:0016763 pentosyltransferase activity 1/336 49/18639 0.0204081632653061 1.13210641399417 0.590381093043134 0.773676306045696 GO:0035254 glutamate receptor binding 1/336 49/18639 0.0204081632653061 1.13210641399417 0.590381093043134 0.773676306045696 GO:0141108 transporter regulator activity 3/336 170/18639 0.0176470588235294 0.978939075630252 0.59429708127941 0.776140403867476 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 4/336 229/18639 0.0174672489082969 0.968964441671865 0.594399537948094 0.776140403867476 GO:0032813 tumor necrosis factor receptor superfamily binding 1/336 50/18639 0.02 1.10946428571429 0.597784640796631 0.779159154790582 GO:0005200 structural constituent of cytoskeleton 2/336 112/18639 0.0178571428571429 0.990593112244898 0.602411215497082 0.781618790470411 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 6/336 349/18639 0.0171919770773639 0.953694228407696 0.603547444143412 0.781618790470411 GO:0005272 sodium channel activity 1/336 51/18639 0.0196078431372549 1.08771008403361 0.60505476617682 0.781618790470411 GO:0016830 carbon-carbon lyase activity 1/336 51/18639 0.0196078431372549 1.08771008403361 0.60505476617682 0.781618790470411 GO:0030544 Hsp70 protein binding 1/336 51/18639 0.0196078431372549 1.08771008403361 0.60505476617682 0.781618790470411 GO:0030159 signaling receptor complex adaptor activity 1/336 52/18639 0.0192307692307692 1.06679258241758 0.61219386659454 0.789436495821734 GO:0004721 phosphoprotein phosphatase activity 3/336 175/18639 0.0171428571428571 0.950969387755102 0.613934568391129 0.790277476333262 GO:0017124 SH3 domain binding 2/336 115/18639 0.0173913043478261 0.964751552795031 0.616815503612156 0.791447745186086 GO:0005544 calcium-dependent phospholipid binding 1/336 53/18639 0.0188679245283019 1.04666442048518 0.619204296509225 0.791447745186086 GO:0008146 sulfotransferase activity 1/336 53/18639 0.0188679245283019 1.04666442048518 0.619204296509225 0.791447745186086 GO:0051018 protein kinase A binding 1/336 53/18639 0.0188679245283019 1.04666442048518 0.619204296509225 0.791447745186086 GO:0043021 ribonucleoprotein complex binding 3/336 177/18639 0.0169491525423729 0.94022397094431 0.621608911741091 0.791881803676643 GO:0005319 lipid transporter activity 3/336 178/18639 0.0168539325842697 0.934941813804173 0.625407030476292 0.791881803676643 GO:0003925 G protein activity 1/336 54/18639 0.0185185185185185 1.02728174603175 0.626088368196134 0.791881803676643 GO:0015485 cholesterol binding 1/336 54/18639 0.0185185185185185 1.02728174603175 0.626088368196134 0.791881803676643 GO:0017069 snRNA binding 1/336 54/18639 0.0185185185185185 1.02728174603175 0.626088368196134 0.791881803676643 GO:0050661 NADP binding 1/336 54/18639 0.0185185185185185 1.02728174603175 0.626088368196134 0.791881803676643 GO:0030170 pyridoxal phosphate binding 1/336 56/18639 0.0178571428571429 0.990593112244898 0.639486479574837 0.805177976447676 GO:0170055 lipid transmembrane transporter activity 1/336 56/18639 0.0178571428571429 0.990593112244898 0.639486479574837 0.805177976447676 GO:0032182 ubiquitin-like protein binding 2/336 120/18639 0.0166666666666667 0.924553571428571 0.639927950978387 0.805177976447676 GO:0003697 single-stranded DNA binding 2/336 121/18639 0.0165289256198347 0.916912632821724 0.644416972096284 0.805841213329913 GO:0004540 RNA nuclease activity 2/336 121/18639 0.0165289256198347 0.916912632821724 0.644416972096284 0.805841213329913 GO:0015108 chloride transmembrane transporter activity 2/336 121/18639 0.0165289256198347 0.916912632821724 0.644416972096284 0.805841213329913 GO:0016504 peptidase activator activity 1/336 57/18639 0.0175438596491228 0.973214285714286 0.646004939611583 0.805841213329913 GO:0070279 vitamin B6 binding 1/336 57/18639 0.0175438596491228 0.973214285714286 0.646004939611583 0.805841213329913 GO:1901981 phosphatidylinositol phosphate binding 3/336 185/18639 0.0162162162162162 0.899565637065637 0.6512592426068 0.811002075699033 GO:0061980 regulatory RNA binding 1/336 58/18639 0.0172413793103448 0.956434729064039 0.652405883551445 0.811038820990323 GO:0015276 ligand-gated monoatomic ion channel activity 3/336 186/18639 0.0161290322580645 0.894729262672811 0.654846953284553 0.811850405608775 GO:0008234 cysteine-type peptidase activity 3/336 187/18639 0.0160427807486631 0.88994461420932 0.658408213811134 0.811850405608775 GO:0031406 carboxylic acid binding 3/336 187/18639 0.0160427807486631 0.88994461420932 0.658408213811134 0.811850405608775 GO:0045309 protein phosphorylated amino acid binding 1/336 59/18639 0.0169491525423729 0.94022397094431 0.658691423787531 0.811850405608775 GO:0070888 E-box binding 1/336 59/18639 0.0169491525423729 0.94022397094431 0.658691423787531 0.811850405608775 GO:0140104 molecular carrier activity 4/336 249/18639 0.0160642570281124 0.891135972461274 0.659768235963054 0.811850405608775 GO:0022834 ligand-gated channel activity 3/336 188/18639 0.0159574468085106 0.885210866261398 0.661943010204104 0.813148266342097 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 1/336 60/18639 0.0166666666666667 0.924553571428571 0.664863634853591 0.814700958514403 GO:0043177 organic acid binding 3/336 189/18639 0.0158730158730159 0.880527210884354 0.665451333882977 0.814700958514403 GO:0019905 syntaxin binding 1/336 61/18639 0.0163934426229508 0.909396955503513 0.670924554100547 0.820018899456224 GO:0022824 transmitter-gated monoatomic ion channel activity 1/336 63/18639 0.0158730158730159 0.880527210884354 0.68272048460174 0.830394831463107 GO:0022835 transmitter-gated channel activity 1/336 63/18639 0.0158730158730159 0.880527210884354 0.68272048460174 0.830394831463107 GO:0016798 hydrolase activity, acting on glycosyl bonds 2/336 130/18639 0.0153846153846154 0.853434065934066 0.682845336616356 0.830394831463107 GO:0005262 calcium channel activity 2/336 131/18639 0.0152671755725191 0.846919302071974 0.686899001034598 0.833927549751034 GO:0004536 DNA nuclease activity 1/336 64/18639 0.015625 0.866768973214286 0.688459390565016 0.834426573539569 GO:0003779 actin binding 7/336 443/18639 0.0158013544018059 0.876551918735892 0.690032227044136 0.834938994723404 GO:0016758 hexosyltransferase activity 3/336 197/18639 0.0152284263959391 0.844769760696157 0.692565562907539 0.83660998114954 GO:0120013 lipid transfer activity 1/336 65/18639 0.0153846153846154 0.853434065934066 0.694094795397864 0.837064487473172 GO:0042054 histone methyltransferase activity 1/336 67/18639 0.0149253731343284 0.82795842217484 0.705062512984173 0.846441272620757 GO:0016779 nucleotidyltransferase activity 2/336 136/18639 0.0147058823529412 0.81578256302521 0.706533624253689 0.846441272620757 GO:0044325 transmembrane transporter binding 2/336 136/18639 0.0147058823529412 0.81578256302521 0.706533624253689 0.846441272620757 GO:0099094 ligand-gated monoatomic cation channel activity 2/336 136/18639 0.0147058823529412 0.81578256302521 0.706533624253689 0.846441272620757 GO:0003777 microtubule motor activity 1/336 68/18639 0.0147058823529412 0.81578256302521 0.710398448566626 0.846878938685338 GO:0030145 manganese ion binding 1/336 68/18639 0.0147058823529412 0.81578256302521 0.710398448566626 0.846878938685338 GO:0032934 sterol binding 1/336 68/18639 0.0147058823529412 0.81578256302521 0.710398448566626 0.846878938685338 GO:0016757 glycosyltransferase activity 4/336 267/18639 0.0149812734082397 0.831059390048154 0.712213122275662 0.847650371757591 GO:0008080 N-acetyltransferase activity 1/336 69/18639 0.0144927536231884 0.803959627329193 0.715638129859051 0.848943271695541 GO:0016279 protein-lysine N-methyltransferase activity 1/336 69/18639 0.0144927536231884 0.803959627329193 0.715638129859051 0.848943271695541 GO:0070851 growth factor receptor binding 2/336 139/18639 0.0143884892086331 0.798175745118191 0.717815565504921 0.850137195035192 GO:0008028 monocarboxylic acid transmembrane transporter activity 1/336 70/18639 0.0142857142857143 0.792474489795918 0.720783288091003 0.850875881551331 GO:0016278 lysine N-methyltransferase activity 1/336 70/18639 0.0142857142857143 0.792474489795918 0.720783288091003 0.850875881551331 GO:0005096 GTPase activator activity 4/336 271/18639 0.014760147601476 0.818792830785451 0.723030535162282 0.852143130726975 GO:0016791 phosphatase activity 4/336 273/18639 0.0146520146520147 0.812794348508634 0.728325443842397 0.856992337487165 GO:0042379 chemokine receptor binding 1/336 72/18639 0.0138888888888889 0.77046130952381 0.730796805615148 0.858508868732358 GO:0022843 voltage-gated monoatomic cation channel activity 2/336 143/18639 0.013986013986014 0.775849150849151 0.732289764092944 0.85887297048704 GO:0005230 extracellular ligand-gated monoatomic ion channel activity 1/336 73/18639 0.0136986301369863 0.759907045009785 0.735668474345331 0.861444052217274 GO:0008194 UDP-glycosyltransferase activity 2/336 145/18639 0.0137931034482759 0.765147783251232 0.739287911158851 0.86377963561927 GO:0031491 nucleosome binding 1/336 74/18639 0.0135135135135135 0.749638030888031 0.740452239971743 0.86377963561927 GO:0001217 DNA-binding transcription repressor activity 4/336 278/18639 0.0143884892086331 0.798175745118191 0.741232387039677 0.86377963561927 GO:0016741 transferase activity, transferring one-carbon groups 3/336 215/18639 0.013953488372093 0.774044850498339 0.747459430691729 0.869640299170185 GO:0031267 small GTPase binding 4/336 283/18639 0.0141342756183746 0.784073700151439 0.753670742821252 0.874785687795806 GO:0003724 RNA helicase activity 1/336 77/18639 0.012987012987013 0.720431354359926 0.754291791405199 0.874785687795806 GO:0019842 vitamin binding 2/336 150/18639 0.0133333333333333 0.739642857142857 0.756103682869024 0.875488474900976 GO:0008186 ATP-dependent activity, acting on RNA 1/336 79/18639 0.0126582278481013 0.702192585895118 0.763106890042237 0.882190449316344 GO:0141003 histone H2AX kinase activity 5/336 354/18639 0.0141242937853107 0.783519975786925 0.767959466968671 0.8863888283295 GO:0004386 helicase activity 2/336 155/18639 0.0129032258064516 0.715783410138249 0.771976748173179 0.889611300275759 GO:0140996 histone H3 kinase activity 5/336 357/18639 0.0140056022408964 0.776935774309724 0.77425386354933 0.890821402435521 GO:0005254 chloride channel activity 1/336 83/18639 0.0120481927710843 0.668351979345955 0.779802299185604 0.893664086475191 GO:0030165 PDZ domain binding 1/336 83/18639 0.0120481927710843 0.668351979345955 0.779802299185604 0.893664086475191 GO:0035173 histone kinase activity 5/336 360/18639 0.0138888888888889 0.77046130952381 0.780417397830952 0.893664086475191 GO:0030695 GTPase regulator activity 7/336 489/18639 0.0143149284253579 0.79409509202454 0.781933375486993 0.89398996945442 GO:0060589 nucleoside-triphosphatase regulator activity 7/336 490/18639 0.0142857142857143 0.792474489795918 0.783683347764357 0.894581934712144 GO:0001664 G protein-coupled receptor binding 4/336 297/18639 0.0134680134680135 0.747113997113997 0.78605333002997 0.89587867755378 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 1/336 86/18639 0.0116279069767442 0.645037375415282 0.791549226302915 0.899318839273735 GO:0050660 flavin adenine dinucleotide binding 1/336 86/18639 0.0116279069767442 0.645037375415282 0.791549226302915 0.899318839273735 GO:0005125 cytokine activity 3/336 234/18639 0.0128205128205128 0.711195054945055 0.796625547751095 0.903672105730148 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 2/336 167/18639 0.0119760479041916 0.664349871685201 0.806444501521993 0.913383319976547 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 1/336 91/18639 0.010989010989011 0.609595761381476 0.809755214447775 0.915704494842811 GO:0043178 alcohol binding 1/336 92/18639 0.0108695652173913 0.602969720496894 0.813201529303584 0.916745823407456 GO:0052689 carboxylic ester hydrolase activity 1/336 92/18639 0.0108695652173913 0.602969720496894 0.813201529303584 0.916745823407456 GO:0051213 dioxygenase activity 1/336 93/18639 0.010752688172043 0.596486175115207 0.816585596061226 0.917710747276239 GO:0051219 phosphoprotein binding 1/336 93/18639 0.010752688172043 0.596486175115207 0.816585596061226 0.917710747276239 GO:0016410 N-acyltransferase activity 1/336 94/18639 0.0106382978723404 0.590140577507599 0.819908535763773 0.91941918801473 GO:0005244 voltage-gated monoatomic ion channel activity 2/336 173/18639 0.0115606936416185 0.641308835672997 0.821881637600974 0.91941918801473 GO:0051020 GTPase binding 4/336 315/18639 0.0126984126984127 0.704421768707483 0.822610999336606 0.91941918801473 GO:0008276 protein methyltransferase activity 1/336 95/18639 0.0105263157894737 0.583928571428571 0.823171449324483 0.91941918801473 GO:0022832 voltage-gated channel activity 2/336 175/18639 0.0114285714285714 0.633979591836735 0.826777184372008 0.922028012064635 GO:0030594 neurotransmitter receptor activity 1/336 97/18639 0.0103092783505155 0.571888807069219 0.829521503180295 0.922863210609931 GO:0005249 voltage-gated potassium channel activity 1/336 98/18639 0.0102040816326531 0.566053206997085 0.832610747864332 0.922863210609931 GO:0008170 N-methyltransferase activity 1/336 98/18639 0.0102040816326531 0.566053206997085 0.832610747864332 0.922863210609931 GO:0030527 structural constituent of chromatin 1/336 98/18639 0.0102040816326531 0.566053206997085 0.832610747864332 0.922863210609931 GO:0008238 exopeptidase activity 1/336 102/18639 0.00980392156862745 0.543855042016807 0.844419525297725 0.934525267326445 GO:0003924 GTPase activity 4/336 331/18639 0.0120845921450151 0.670371169615883 0.850641402524769 0.939978170826457 GO:0000149 SNARE binding 1/336 106/18639 0.00943396226415094 0.523332210242588 0.855397535163993 0.941326796909436 GO:0008013 beta-catenin binding 1/336 106/18639 0.00943396226415094 0.523332210242588 0.855397535163993 0.941326796909436 GO:0140597 protein carrier chaperone 2/336 188/18639 0.0106382978723404 0.590140577507599 0.855751633554033 0.941326796909436 GO:0004175 endopeptidase activity 5/336 405/18639 0.0123456790123457 0.684854497354497 0.857984277219079 0.942354894494782 GO:0004843 cysteine-type deubiquitinase activity 1/336 108/18639 0.00925925925925926 0.513640873015873 0.860593378647422 0.943792738516659 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 3/336 268/18639 0.0111940298507463 0.62096881663113 0.864663614318717 0.946427443437858 GO:0004222 metalloendopeptidase activity 1/336 110/18639 0.00909090909090909 0.504301948051948 0.865603061215892 0.946427443437858 GO:1902936 phosphatidylinositol bisphosphate binding 1/336 111/18639 0.00900900900900901 0.499758687258687 0.868040179864036 0.947664918167354 GO:0043022 ribosome binding 1/336 112/18639 0.00892857142857143 0.495296556122449 0.870433233597071 0.94885064202924 GO:0101005 deubiquitinase activity 1/336 115/18639 0.00869565217391304 0.482375776397515 0.877355878076361 0.954963069690312 GO:0008168 methyltransferase activity 2/336 204/18639 0.00980392156862745 0.543855042016807 0.885324532274437 0.961367020207263 GO:0035091 phosphatidylinositol binding 3/336 284/18639 0.0105633802816901 0.585984657947686 0.889128496543272 0.961367020207263 GO:0051015 actin filament binding 2/336 209/18639 0.00956937799043062 0.530844155844156 0.893350463274859 0.961367020207263 GO:0019783 ubiquitin-like protein peptidase activity 1/336 127/18639 0.0078740157480315 0.43679696287964 0.901548980187399 0.961367020207263 GO:0046982 protein heterodimerization activity 4/336 369/18639 0.010840108401084 0.601335656213705 0.902551645811616 0.961367020207263 GO:0001653 peptide receptor activity 1/336 128/18639 0.0078125 0.433384486607143 0.903335904488233 0.961367020207263 GO:0031490 chromatin DNA binding 1/336 128/18639 0.0078125 0.433384486607143 0.903335904488233 0.961367020207263 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 1/336 130/18639 0.00769230769230769 0.426717032967033 0.906813320846924 0.961367020207263 GO:0004842 ubiquitin-protein transferase activity 5/336 449/18639 0.0111358574610245 0.617741807190582 0.910322916680306 0.961367020207263 GO:0140098 catalytic activity, acting on RNA 4/336 387/18639 0.0103359173126615 0.573366555924695 0.921052885091637 0.961367020207263 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 2/336 243/18639 0.00823045267489712 0.456569664902998 0.935505196334861 0.961367020207263 GO:0019787 ubiquitin-like protein transferase activity 5/336 479/18639 0.0104384133611691 0.579052341186997 0.935540792052891 0.961367020207263 GO:0000510 H3-H4 histone complex chaperone activity 1/336 151/18639 0.00662251655629139 0.367372280037843 0.936586786973702 0.961367020207263 GO:0140584 chromatin extrusion motor activity 1/336 151/18639 0.00662251655629139 0.367372280037843 0.936586786973702 0.961367020207263 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 1/336 151/18639 0.00662251655629139 0.367372280037843 0.936586786973702 0.961367020207263 GO:0140849 ATP-dependent H2AZ histone chaperone activity 1/336 151/18639 0.00662251655629139 0.367372280037843 0.936586786973702 0.961367020207263 GO:0004676 3-phosphoinositide-dependent protein kinase activity 2/336 245/18639 0.00816326530612245 0.452842565597668 0.937415098260353 0.961367020207263 GO:0004711 ribosomal protein S6 kinase activity 2/336 245/18639 0.00816326530612245 0.452842565597668 0.937415098260353 0.961367020207263 GO:0035175 histone H3S10 kinase activity 2/336 245/18639 0.00816326530612245 0.452842565597668 0.937415098260353 0.961367020207263 GO:0035979 histone H2AXS139 kinase activity 2/336 245/18639 0.00816326530612245 0.452842565597668 0.937415098260353 0.961367020207263 GO:0044022 histone H3S28 kinase activity 2/336 245/18639 0.00816326530612245 0.452842565597668 0.937415098260353 0.961367020207263 GO:0044023 histone H4S1 kinase activity 2/336 245/18639 0.00816326530612245 0.452842565597668 0.937415098260353 0.961367020207263 GO:0044024 histone H2AS1 kinase activity 2/336 245/18639 0.00816326530612245 0.452842565597668 0.937415098260353 0.961367020207263 GO:0044025 histone H2BS14 kinase activity 2/336 245/18639 0.00816326530612245 0.452842565597668 0.937415098260353 0.961367020207263 GO:0072354 histone H3T3 kinase activity 2/336 245/18639 0.00816326530612245 0.452842565597668 0.937415098260353 0.961367020207263 GO:0072371 histone H2AS121 kinase activity 2/336 245/18639 0.00816326530612245 0.452842565597668 0.937415098260353 0.961367020207263 GO:0072518 Rho-dependent protein serine/threonine kinase activity 2/336 245/18639 0.00816326530612245 0.452842565597668 0.937415098260353 0.961367020207263 GO:0140823 histone H2BS36 kinase activity 2/336 245/18639 0.00816326530612245 0.452842565597668 0.937415098260353 0.961367020207263 GO:0140855 histone H3S57 kinase activity 2/336 245/18639 0.00816326530612245 0.452842565597668 0.937415098260353 0.961367020207263 GO:0140995 histone H2A kinase activity 2/336 245/18639 0.00816326530612245 0.452842565597668 0.937415098260353 0.961367020207263 GO:0140997 histone H4 kinase activity 2/336 245/18639 0.00816326530612245 0.452842565597668 0.937415098260353 0.961367020207263 GO:0140998 histone H2B kinase activity 2/336 245/18639 0.00816326530612245 0.452842565597668 0.937415098260353 0.961367020207263 GO:1990244 histone H2AT120 kinase activity 2/336 245/18639 0.00816326530612245 0.452842565597668 0.937415098260353 0.961367020207263 GO:0015616 DNA translocase activity 1/336 152/18639 0.00657894736842105 0.364955357142857 0.937739255579112 0.961367020207263 GO:0140674 ATP-dependent histone chaperone activity 1/336 152/18639 0.00657894736842105 0.364955357142857 0.937739255579112 0.961367020207263 GO:0004677 DNA-dependent protein kinase activity 2/336 246/18639 0.00813008130081301 0.451001742160279 0.93834985950147 0.961367020207263 GO:0140857 histone H3T45 kinase activity 2/336 246/18639 0.00813008130081301 0.451001742160279 0.93834985950147 0.961367020207263 GO:0003774 cytoskeletal motor activity 1/336 153/18639 0.0065359477124183 0.362570028011204 0.938870840483392 0.961367020207263 GO:0061775 cohesin loader activity 1/336 153/18639 0.0065359477124183 0.362570028011204 0.938870840483392 0.961367020207263 GO:0035402 histone H3T11 kinase activity 2/336 247/18639 0.00809716599190283 0.449175824175824 0.93927139240503 0.961367020207263 GO:0035403 histone H3T6 kinase activity 2/336 247/18639 0.00809716599190283 0.449175824175824 0.93927139240503 0.961367020207263 GO:0005506 iron ion binding 1/336 154/18639 0.00649350649350649 0.360215677179963 0.93998191900755 0.961367020207263 GO:0004679 AMP-activated protein kinase activity 2/336 248/18639 0.00806451612903226 0.447364631336406 0.940179868246772 0.961367020207263 GO:0140097 catalytic activity, acting on DNA 3/336 336/18639 0.00892857142857143 0.495296556122449 0.943644583943655 0.962745458080513 GO:0140658 ATP-dependent chromatin remodeler activity 1/336 158/18639 0.00632911392405063 0.351096292947559 0.944228480366627 0.962745458080513 GO:0003689 DNA clamp loader activity 1/336 160/18639 0.00625 0.346707589285714 0.946238044888984 0.962745458080513 GO:0016755 aminoacyltransferase activity 5/336 496/18639 0.0100806451612903 0.559205789170507 0.946832310013067 0.962745458080513 GO:0140713 histone chaperone activity 1/336 164/18639 0.00609756097560976 0.338251306620209 0.950043157345729 0.964659205920279 GO:0061630 ubiquitin protein ligase activity 3/336 353/18639 0.0084985835694051 0.47144374747066 0.95520288138612 0.968543703751848 GO:0005126 cytokine receptor binding 2/336 275/18639 0.00727272727272727 0.403441558441558 0.960349871837389 0.971662109088751 GO:0008017 microtubule binding 2/336 276/18639 0.0072463768115942 0.401979813664596 0.960955088602925 0.971662109088751 GO:0008237 metallopeptidase activity 1/336 184/18639 0.00543478260869565 0.301484860248447 0.965398887276857 0.973531852993183 GO:0061659 ubiquitin-like protein ligase activity 3/336 372/18639 0.00806451612903226 0.447364631336406 0.965486135199851 0.973531852993183 GO:0008094 ATP-dependent activity, acting on DNA 1/336 210/18639 0.00476190476190476 0.264158163265306 0.978547758945883 0.985333804430944 GO:0005085 guanyl-nucleotide exchange factor activity 1/336 230/18639 0.00434782608695652 0.241187888198758 0.985155494954058 0.990613420133859 GO:0003730 mRNA 3'-UTR binding 1/336 262/18639 0.00381679389312977 0.211729825517993 0.991770952752074 0.995806835021791 GO:0015631 tubulin binding 2/336 385/18639 0.00519480519480519 0.28817254174397 0.993063565503825 0.995806835021791 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 2/336 484/18639 0.00413223140495868 0.229228158205431 0.998648584306106 0.998798379722964 GO:0001216 DNA-binding transcription activator activity 2/336 491/18639 0.00407331975560081 0.225960139656677 0.998798379722964 0.998798379722964