category subcategory ID Description GeneRatio BgRatio FoldEnrichment geneName zScore Cellular Processes Cellular community - eukaryotes hsa04520 Adherens junction 3/37 93/9376 8.1743679163034 TCF7L2/ROCK2/IQGAP1 4.3764024854417 Human Diseases Infectious disease: parasitic hsa05146 Amoebiasis 3/37 103/9376 7.38073996326424 IL1R2/LAMA3/LAMB1 4.09841413783473 Cellular Processes Cellular community - eukaryotes hsa04510 Focal adhesion 4/37 203/9376 4.9932099587272 LAMA3/ROCK2/FLNB/LAMB1 3.62035185037679 Human Diseases Cancer: specific types hsa05215 Prostate cancer 3/37 106/9376 7.1718510963794 HSP90B1/IL1R2/TCF7L2 4.02221070665427 Metabolism Glycan biosynthesis and metabolism hsa00512 Mucin type O-glycan biosynthesis 2/37 36/9376 14.0780780780781 GALNT7/GALNT1 4.9483231178151 Metabolism Glycan biosynthesis and metabolism hsa00514 Other types of O-glycan biosynthesis 2/37 49/9376 10.3430777716492 GALNT7/GALNT1 4.12717921861668 Human Diseases Infectious disease: bacterial hsa05132 Salmonella infection 4/37 248/9376 4.0871839581517 HSP90B1/TCF7L2/GCC2/ROCK2 3.10125049141405 NA NA hsa04518 Integrin signaling 3/37 154/9376 4.93646893646894 LAMA3/FLNB/LAMB1 3.10020878575415 Metabolism Amino acid metabolism hsa00310 Lysine degradation 2/37 63/9376 8.04461604461604 KMT2E/PLOD2 3.53117396122934 Genetic Information Processing Chromosome hsa03083 Polycomb repressive complex 2/37 83/9376 6.1061543471182 MTF2/USP16 2.94097497123932 Human Diseases Cancer: overview hsa05202 Transcriptional misregulation in cancer 3/37 201/9376 3.78217022993142 IL1R2/ARNT2/NUPR1 2.50966066593771 Human Diseases Cardiovascular disease hsa05412 Arrhythmogenic right ventricular cardiomyopathy 2/37 86/9376 5.8931489629164 DSP/TCF7L2 2.86923499030688 Human Diseases Cancer: overview hsa05205 Proteoglycans in cancer 3/37 204/9376 3.72655007949126 IGF2/ROCK2/IQGAP1 2.47818002534023 Organismal Systems Immune system hsa04610 Complement and coagulation cascades 2/37 88/9376 5.75921375921376 CLU/C1S 2.82326573141744 Environmental Information Processing Signaling molecules and interaction hsa04512 ECM-receptor interaction 2/37 89/9376 5.6945034922563 LAMA3/LAMB1 2.80080749250369 Human Diseases Cancer: specific types hsa05222 Small cell lung cancer 2/37 93/9376 5.44957861086893 LAMA3/LAMB1 2.71426655545825 Environmental Information Processing Signal transduction hsa04151 PI3K-Akt signaling pathway 4/37 362/9376 2.80005972823652 HSP90B1/IGF2/LAMA3/LAMB1 2.19846085284764 Cellular Processes Cell motility hsa04820 Cytoskeleton in muscle cells 3/37 233/9376 3.2627305417005 DSP/TNNI2/COL11A1 2.20141921074412 Human Diseases Infectious disease: viral hsa05171 Coronavirus disease - COVID-19 3/37 238/9376 3.19418578242108 RPS26/RPS4Y1/C1S 2.15810519834509 Human Diseases Infectious disease: parasitic hsa05145 Toxoplasmosis 2/37 112/9376 4.52509652509652 LAMA3/LAMB1 2.36220216998297 Human Diseases Cardiovascular disease hsa05418 Fluid shear stress and atherosclerosis 2/37 142/9376 3.56909021697754 HSP90B1/IL1R2 1.94162298689639 Cellular Processes Cell growth and death hsa04110 Cell cycle 2/37 158/9376 3.20766335956209 ATRX/RAD21 1.76148664098483 Human Diseases Cancer: specific types hsa05216 Thyroid cancer 1/37 37/9376 6.84879474068663 TCF7L2 2.24364099787022 Human Diseases Infectious disease: viral hsa05165 Human papillomavirus infection 3/37 333/9376 2.28293158022888 LAMA3/TCF7L2/LAMB1 1.50039517747259 Human Diseases Cancer: specific types hsa05225 Hepatocellular carcinoma 2/37 170/9376 2.981240063593 IGF2/TCF7L2 1.6408254722341 Genetic Information Processing Folding, sorting and degradation hsa04141 Protein processing in endoplasmic reticulum 2/37 174/9376 2.91270580925753 HSP90B1/PDIA3 1.60294270406701 Environmental Information Processing Signal transduction hsa04310 Wnt signaling pathway 2/37 178/9376 2.84725174612815 TCF7L2/ROCK2 1.566122384015 Genetic Information Processing Replication and repair hsa03410 Base excision repair 1/37 44/9376 5.75921375921376 HMGB1 1.99163842780188 Environmental Information Processing Signal transduction hsa04340 Hedgehog signaling pathway 1/37 56/9376 4.52509652509652 SCUBE2 1.6653034558802 Human Diseases Cancer: specific types hsa05213 Endometrial cancer 1/37 59/9376 4.29500687127806 TCF7L2 1.59801405668911 Human Diseases Cardiovascular disease hsa05417 Lipid and atherosclerosis 2/37 216/9376 2.34634634634635 HSP90B1/ROCK2 1.26000493872906 NA NA hsa04382 Cornified envelope formation 2/37 217/9376 2.3355336903724 DSP/LAMA3 1.25284400165986 NA NA hsa04519 Cadherin signaling 3/37 404/9376 1.88172330746588 DSP/TCF7L2/ROCK2 1.14028834062556 Environmental Information Processing Signal transduction hsa04330 Notch signaling pathway 1/37 62/9376 4.0871839581517 SPEN 1.53506422095621 Genetic Information Processing Translation hsa03010 Ribosome 2/37 222/9376 2.28293158022888 RPS26/RPS4Y1 1.2176173882355 Human Diseases Cancer: specific types hsa05217 Basal cell carcinoma 1/37 63/9376 4.02230802230802 TCF7L2 1.51495771005789 Human Diseases Infectious disease: viral hsa05163 Human cytomegalovirus infection 2/37 227/9376 2.23264674365996 PDIA3/ROCK2 1.18331688086475 Cellular Processes Cell motility hsa04810 Regulation of actin cytoskeleton 2/37 232/9376 2.18452935694315 ROCK2/IQGAP1 1.14989457451859 Human Diseases Cancer: specific types hsa05221 Acute myeloid leukemia 1/37 68/9376 3.72655007949126 TCF7L2 1.42028683183222 Human Diseases Cancer: specific types hsa05211 Renal cell carcinoma 1/37 70/9376 3.62007722007722 ARNT2 1.384898355838 Organismal Systems Endocrine system hsa04918 Thyroid hormone synthesis 1/37 75/9376 3.37873873873874 HSP90B1 1.3018137889802 Genetic Information Processing Folding, sorting and degradation hsa03018 RNA degradation 1/37 78/9376 3.24878724878725 PABPC1 1.25527018312332 Human Diseases Infectious disease: bacterial hsa05133 Pertussis 1/37 78/9376 3.24878724878725 C1S 1.25527018312332 Organismal Systems Immune system hsa04612 Antigen processing and presentation 1/37 82/9376 3.09030982201714 PDIA3 1.19660982916674 Human Diseases Cancer: specific types hsa05210 Colorectal cancer 1/37 87/9376 2.91270580925753 TCF7L2 1.12813126211898 Organismal Systems Immune system hsa04657 IL-17 signaling pathway 1/37 94/9376 2.69580218516389 HSP90B1 1.0400510285697 Human Diseases Infectious disease: bacterial hsa05150 Staphylococcus aureus infection 1/37 99/9376 2.55965055965056 C1S 0.981923009308795 Organismal Systems Immune system hsa04640 Hematopoietic cell lineage 1/37 100/9376 2.53405405405405 IL1R2 0.970725873289877 Environmental Information Processing Signaling molecules and interaction hsa04060 Cytokine-cytokine receptor interaction 2/37 298/9376 1.70070741882822 IL1R2/INHA 0.773724004750958 Organismal Systems Endocrine system hsa04916 Melanogenesis 1/37 101/9376 2.50896440995451 TCF7L2 0.959663632425361 Genetic Information Processing Translation hsa03015 mRNA surveillance pathway 1/37 103/9376 2.46024665442141 PABPC1 0.937931269360952 Organismal Systems Digestive system hsa04974 Protein digestion and absorption 1/37 103/9376 2.46024665442141 COL11A1 0.937931269360952 Organismal Systems Immune system hsa04670 Leukocyte transendothelial migration 1/37 116/9376 2.18452935694315 ROCK2 0.807989361085098 Organismal Systems Endocrine system hsa04919 Thyroid hormone signaling pathway 1/37 122/9376 2.07709348692955 MED13L 0.753711045894372 Environmental Information Processing Signal transduction hsa04071 Sphingolipid signaling pathway 1/37 125/9376 2.02724324324324 ROCK2 0.727729988641188 Organismal Systems Immune system hsa04611 Platelet activation 1/37 126/9376 2.01115401115401 ROCK2 0.719230386938412 Organismal Systems Circulatory system hsa04270 Vascular smooth muscle contraction 1/37 134/9376 1.89108511496571 ROCK2 0.65392044924189 Cellular Processes Cell growth and death hsa04210 Apoptosis 1/37 137/9376 1.84967449201026 CTSV 0.630574919467259 Human Diseases Infectious disease: bacterial hsa05135 Yersinia infection 1/37 138/9376 1.83627105366236 ROCK2 0.622922390177359 Organismal Systems Endocrine system hsa04915 Estrogen signaling pathway 1/37 139/9376 1.82306047054249 HSP90B1 0.615332685873207 Human Diseases Immune disease hsa05322 Systemic lupus erythematosus 1/37 143/9376 1.77206577206577 C1S 0.585581317992095 Human Diseases Endocrine and metabolic disease hsa04936 Alcoholic liver disease 1/37 144/9376 1.75975975975976 TCF7L2 0.578290354132247 Human Diseases Cancer: specific types hsa05224 Breast cancer 1/37 148/9376 1.71219868517166 TCF7L2 0.549685833999454 Human Diseases Cancer: specific types hsa05226 Gastric cancer 1/37 150/9376 1.68936936936937 TCF7L2 0.535706849788312 Organismal Systems Endocrine system hsa04921 Oxytocin signaling pathway 1/37 154/9376 1.64548964548965 ROCK2 0.508362367989468 Human Diseases Endocrine and metabolic disease hsa04934 Cushing syndrome 1/37 155/9376 1.63487358326068 TCF7L2 0.501649527244806 Cellular Processes Transport and catabolism hsa04148 Efferocytosis 1/37 157/9376 1.6140471681873 STAB2 0.488366610978587 Environmental Information Processing Signal transduction hsa04390 Hippo signaling pathway 1/37 157/9376 1.6140471681873 TCF7L2 0.488366610978587 Environmental Information Processing Signal transduction hsa04022 cGMP-PKG signaling pathway 1/37 166/9376 1.52653858677955 ROCK2 0.430814929450174 Cellular Processes Cell growth and death hsa04217 Necroptosis 1/37 168/9376 1.50836550836551 HMGB1 0.418489315945803 Cellular Processes Transport and catabolism hsa04140 Autophagy - animal 1/37 169/9376 1.49944026867104 HMGB1 0.41238622382635 Cellular Processes Cellular community - eukaryotes hsa04530 Tight junction 1/37 170/9376 1.4906200317965 ROCK2 0.406322212109969 Human Diseases Infectious disease: viral hsa05168 Herpes simplex virus 1 infection 1/37 180/9376 1.40780780780781 PDIA3 0.347719158729181 Organismal Systems Development and regeneration hsa04360 Axon guidance 1/37 184/9376 1.37720329024677 ROCK2 0.325248789217796 Organismal Systems Immune system hsa04062 Chemokine signaling pathway 1/37 193/9376 1.31298137515754 ROCK2 0.276529309544251 Cellular Processes Cell motility hsa04814 Motor proteins 1/37 194/9376 1.30621342992477 TNNI2 0.271264378447668 Organismal Systems Immune system hsa04613 Neutrophil extracellular trap formation 1/37 195/9376 1.2995148995149 HMGB1 0.26602782023904 Human Diseases Infectious disease: viral hsa05167 Kaposi sarcoma-associated herpesvirus infection 1/37 196/9376 1.29288472145615 TCF7L2 0.260819299760538 Human Diseases Infectious disease: bacterial hsa05130 Pathogenic Escherichia coli infection 1/37 200/9376 1.26702702702703 ROCK2 0.24025909034383 Human Diseases Infectious disease: viral hsa05169 Epstein-Barr virus infection 1/37 205/9376 1.23612392880686 PDIA3 0.2151517570193 Human Diseases Infectious disease: viral hsa05170 Human immunodeficiency virus 1 infection 1/37 214/9376 1.18413740843647 PDIA3 0.171510250818948 Human Diseases Cancer: overview hsa05207 Chemical carcinogenesis - receptor activation 1/37 217/9376 1.1677668451862 HSP90B1 0.157379545858046 NA NA hsa04081 Hormone signaling 1/37 219/9376 1.15710230778724 IGF2 0.148069062823387 Human Diseases Infectious disease: viral hsa05166 Human T-cell leukemia virus 1 infection 1/37 224/9376 1.13127413127413 IL1R2 0.125164586497435 Environmental Information Processing Signal transduction hsa04024 cAMP signaling pathway 1/37 226/9376 1.12126285577613 ROCK2 0.116146941193818 Environmental Information Processing Signal transduction hsa04014 Ras signaling pathway 1/37 238/9376 1.06472859414036 IGF2 0.0636642150427856 Genetic Information Processing Transcription hsa03040 Spliceosome 1/37 243/9376 1.04282059837615 RBM25 0.0425682162673617 Cellular Processes Transport and catabolism hsa04142 Lysosome biogenesis 1/37 250/9376 1.01362162162162 CTSV 0.0137402583007833 Human Diseases Infectious disease: bacterial hsa05131 Shigellosis 1/37 253/9376 1.00160239290674 ROCK2 0.00162628534895355 NA NA hsa04517 IgSF CAM signaling 1/37 299/9376 0.847509717074934 IQGAP1 -0.168671966845664 Environmental Information Processing Signal transduction hsa04010 MAPK signaling pathway 1/37 300/9376 0.844684684684685 IGF2 -0.172093306516249