category subcategory ID Description GeneRatio BgRatio FoldEnrichment geneName zScore Genetic Information Processing Translation hsa03010 Ribosome 13/27 222/9376 20.335001668335 RPS16/RPS6/RPS18/RPLP1/RPS12/RPL13A/RPL7A/RPS23/RPS29/RPL11/RPS5/RPL29/RPL3 15.6675174635297 Human Diseases Infectious disease: viral hsa05171 Coronavirus disease - COVID-19 13/27 238/9376 18.9679427326486 RPS16/RPS6/RPS18/RPLP1/RPS12/RPL13A/RPL7A/RPS23/RPS29/RPL11/RPS5/RPL29/RPL3 15.088504502333 Human Diseases Immune disease hsa05323 Rheumatoid arthritis 3/27 95/9376 10.966081871345 HLA-DRA/CCL3/CXCL3 5.24654989368496 Environmental Information Processing Signaling molecules and interaction hsa04060 Cytokine-cytokine receptor interaction 4/27 298/9376 4.66119811086254 CSH1/CCL3/CSH2/CXCL3 3.45160598062028 Human Diseases Immune disease hsa05320 Autoimmune thyroid disease 2/27 54/9376 12.8614540466392 CGA/HLA-DRA 4.69748283319563 Organismal Systems Endocrine system hsa04929 GnRH secretion 2/27 65/9376 10.6849002849003 CGA/SPP1 4.2105478676312 Environmental Information Processing Signal transduction hsa04151 PI3K-Akt signaling pathway 4/27 362/9376 3.83711888684264 CSH1/SPP1/RPS6/CSH2 2.95840742409164 Organismal Systems Immune system hsa04612 Antigen processing and presentation 2/27 82/9376 8.46973803071364 HLA-DRA/CD74 3.6508660882502 NA NA hsa04081 Hormone signaling 3/27 219/9376 4.75697615423643 CSH1/CGA/CSH2 3.02321357699868 Organismal Systems Immune system hsa04657 IL-17 signaling pathway 2/27 94/9376 7.38849487785658 S100A9/CXCL3 3.34523503131298 Environmental Information Processing Signaling molecules and interaction hsa04061 Viral protein interaction with cytokine and cytokine receptor 2/27 100/9376 6.94518518518519 CCL3/CXCL3 3.21195873631782 Organismal Systems Immune system hsa04620 Toll-like receptor signaling pathway 2/27 109/9376 6.37172952769283 SPP1/CCL3 3.03139650250709 Environmental Information Processing Signal transduction hsa04066 HIF-1 signaling pathway 2/27 110/9376 6.31380471380471 RPS6/GAPDH 3.01259481827636 Organismal Systems Endocrine system hsa04935 Growth hormone synthesis, secretion and action 2/27 122/9376 5.69277474195507 CSH1/CSH2 2.80368886149387 Environmental Information Processing Signal transduction hsa04371 Apelin signaling pathway 2/27 140/9376 4.96084656084656 SPP1/RPS6 2.53743551834141 Cellular Processes Cell growth and death hsa04217 Necroptosis 2/27 168/9376 4.13403880070547 SLC25A6/FTL 2.20273014282423 Environmental Information Processing Signal transduction hsa04630 JAK-STAT signaling pathway 2/27 168/9376 4.13403880070547 CSH1/CSH2 2.20273014282423 Human Diseases Infectious disease: viral hsa05164 Influenza A 2/27 173/9376 4.01455791051167 SLC25A6/HLA-DRA 2.15063600424049 Human Diseases Immune disease hsa05310 Asthma 1/27 32/9376 10.8518518518519 HLA-DRA 2.99993183792715 Environmental Information Processing Signaling molecules and interaction hsa04080 Neuroactive ligand-receptor interaction 3/27 370/9376 2.81561561561562 CSH1/CGA/CSH2 1.9148895999787 Human Diseases Infectious disease: viral hsa05168 Herpes simplex virus 1 infection 2/27 180/9376 3.85843621399177 HLA-DRA/CD74 2.08089524122064 Human Diseases Infectious disease: bacterial hsa05152 Tuberculosis 2/27 181/9376 3.83711888684264 HLA-DRA/CD74 2.07121840168724 Organismal Systems Immune system hsa04062 Chemokine signaling pathway 2/27 193/9376 3.59854154672808 CCL3/CXCL3 1.96020263047679 Human Diseases Immune disease hsa05330 Allograft rejection 1/27 39/9376 8.90408357075024 HLA-DRA 2.65806188486047 Cellular Processes Cell growth and death hsa04216 Ferroptosis 1/27 42/9376 8.26807760141093 FTL 2.53685265267182 Human Diseases Cardiovascular disease hsa05415 Diabetic cardiomyopathy 2/27 205/9376 3.38789521228546 SLC25A6/GAPDH 1.85767094684952 Human Diseases Endocrine and metabolic disease hsa04940 Type I diabetes mellitus 1/27 44/9376 7.89225589225589 HLA-DRA 2.46255141571147 Human Diseases Immune disease hsa05332 Graft-versus-host disease 1/27 45/9376 7.71687242798354 HLA-DRA 2.42713650631351 Metabolism Metabolism of cofactors and vitamins hsa00860 Porphyrin metabolism 1/27 46/9376 7.54911433172303 FTL 2.39279562845365 Human Diseases Cardiovascular disease hsa05417 Lipid and atherosclerosis 2/27 216/9376 3.21536351165981 CCL3/CXCL3 1.7701459569363 Organismal Systems Immune system hsa04672 Intestinal immune network for IgA production 1/27 50/9376 6.94518518518519 HLA-DRA 2.26510127169399 Human Diseases Infectious disease: viral hsa05166 Human T-cell leukemia virus 1 infection 2/27 224/9376 3.1005291005291 SLC25A6/HLA-DRA 1.7099351756529 Organismal Systems Endocrine system hsa04913 Ovarian steroidogenesis 1/27 52/9376 6.67806267806268 CGA 2.20640717959035 Organismal Systems Digestive system hsa04979 Cholesterol metabolism 1/27 52/9376 6.67806267806268 APOC1 2.20640717959035 Human Diseases Infectious disease: bacterial hsa05134 Legionellosis 1/27 56/9376 6.2010582010582 CXCL3 2.09779338385494 Organismal Systems Endocrine system hsa04923 Regulation of lipolysis in adipocytes 1/27 59/9376 5.8857501569366 CGA 2.02303852469404 Organismal Systems Digestive system hsa04978 Mineral absorption 1/27 61/9376 5.69277474195507 FTL 1.9760054424019 Human Diseases Immune disease hsa05321 Inflammatory bowel disease 1/27 66/9376 5.26150392817059 HLA-DRA 1.8670027634512 Metabolism Carbohydrate metabolism hsa00010 Glycolysis / Gluconeogenesis 1/27 67/9376 5.18297401879491 GAPDH 1.84652840899365 Human Diseases Cardiovascular disease hsa05416 Viral myocarditis 1/27 70/9376 4.96084656084656 HLA-DRA 1.78747696950297 Organismal Systems Endocrine system hsa04917 Prolactin signaling pathway 1/27 71/9376 4.89097548252478 CGA 1.76853809974425 Human Diseases Infectious disease: bacterial hsa05120 Epithelial cell signaling in Helicobacter pylori infection 1/27 71/9376 4.89097548252478 CXCL3 1.76853809974425 Metabolism Global and overview maps hsa01230 Biosynthesis of amino acids 1/27 75/9376 4.63012345679012 GAPDH 1.69618080864147 Organismal Systems Endocrine system hsa04918 Thyroid hormone synthesis 1/27 75/9376 4.63012345679012 CGA 1.69618080864147 Human Diseases Infectious disease: parasitic hsa05140 Leishmaniasis 1/27 78/9376 4.45204178537512 HLA-DRA 1.64518035438079 Human Diseases Drug resistance: antineoplastic hsa01521 EGFR tyrosine kinase inhibitor resistance 1/27 80/9376 4.34074074074074 RPS6 1.61259255248594 Environmental Information Processing Signaling molecules and interaction hsa04512 ECM-receptor interaction 1/27 89/9376 3.90178942987932 SPP1 1.47811462927526 Organismal Systems Immune system hsa04658 Th1 and Th2 cell differentiation 1/27 93/9376 3.73397052966945 HLA-DRA 1.4238887814097 Organismal Systems Endocrine system hsa04912 GnRH signaling pathway 1/27 93/9376 3.73397052966945 CGA 1.4238887814097 Human Diseases Infectious disease: bacterial hsa05150 Staphylococcus aureus infection 1/27 99/9376 3.50766928544706 HLA-DRA 1.34793521673795 Organismal Systems Immune system hsa04640 Hematopoietic cell lineage 1/27 100/9376 3.47259259259259 HLA-DRA 1.33584827583216 Human Diseases Infectious disease: parasitic hsa05142 Chagas disease 1/27 103/9376 3.37144911902193 CCL3 1.30049064918034 Human Diseases Infectious disease: parasitic hsa05146 Amoebiasis 1/27 103/9376 3.37144911902193 CXCL3 1.30049064918034 Environmental Information Processing Signal transduction hsa04064 NF-kappa B signaling pathway 1/27 105/9376 3.30723104056437 CXCL3 1.27763672032541 Organismal Systems Immune system hsa04659 Th17 cell differentiation 1/27 109/9376 3.18586476384642 HLA-DRA 1.23353619461244 Human Diseases Infectious disease: parasitic hsa05145 Toxoplasmosis 1/27 112/9376 3.1005291005291 HLA-DRA 1.2017755971301 Metabolism Global and overview maps hsa01200 Carbon metabolism 1/27 116/9376 2.99361430395913 GAPDH 1.16104641726408 Environmental Information Processing Signal transduction hsa04668 TNF signaling pathway 1/27 119/9376 2.91814503579209 CXCL3 1.13163072731674 Human Diseases Neurodegenerative disease hsa05010 Alzheimer disease 2/27 388/9376 1.78999618174876 SLC25A6/GAPDH 0.854071566205466 Organismal Systems Endocrine system hsa04910 Insulin signaling pathway 1/27 138/9376 2.51637144390768 RPS6 0.964364249210129 Human Diseases Immune disease hsa05322 Systemic lupus erythematosus 1/27 143/9376 2.42838642838643 HLA-DRA 0.924969167685457 Human Diseases Endocrine and metabolic disease hsa04936 Alcoholic liver disease 1/27 144/9376 2.41152263374486 CXCL3 0.917288893198679 Human Diseases Neurodegenerative disease hsa05017 Spinocerebellar ataxia 1/27 144/9376 2.41152263374486 SLC25A6 0.917288893198679 NA NA hsa04518 Integrin signaling 1/27 154/9376 2.25493025493026 SPP1 0.843824890332214 Cellular Processes Transport and catabolism hsa04145 Phagosome 1/27 155/9376 2.24038231780167 HLA-DRA 0.83679166370687 Cellular Processes Cell growth and death hsa04218 Cellular senescence 1/27 157/9376 2.21184241566407 SLC25A6 0.822884739325861 Environmental Information Processing Signal transduction hsa04150 mTOR signaling pathway 1/27 158/9376 2.19784341303329 RPS6 0.816009436387541 Environmental Information Processing Signaling molecules and interaction hsa04514 Cell adhesion molecule (CAM) interaction 1/27 160/9376 2.17037037037037 HLA-DRA 0.802411265091301 Environmental Information Processing Signal transduction hsa04022 cGMP-PKG signaling pathway 1/27 166/9376 2.09192324854975 SLC25A6 0.762783485960776 Organismal Systems Immune system hsa04621 NOD-like receptor signaling pathway 1/27 187/9376 1.85700138641315 CXCL3 0.636140641355787 Organismal Systems Immune system hsa04613 Neutrophil extracellular trap formation 1/27 195/9376 1.78081671415005 SLC25A6 0.592115396019916 Human Diseases Infectious disease: viral hsa05167 Kaposi sarcoma-associated herpesvirus infection 1/27 196/9376 1.77173091458806 CXCL3 0.586755992029861 Human Diseases Infectious disease: bacterial hsa05130 Pathogenic Escherichia coli infection 1/27 200/9376 1.7362962962963 GAPDH 0.565621425090067 Cellular Processes Cellular community - eukaryotes hsa04510 Focal adhesion 1/27 203/9376 1.7106367451195 SPP1 0.550078818918044 Human Diseases Cancer: overview hsa05205 Proteoglycans in cancer 1/27 204/9376 1.70225127087872 RPS6 0.544954866087618 Human Diseases Infectious disease: viral hsa05169 Epstein-Barr virus infection 1/27 205/9376 1.69394760614273 HLA-DRA 0.539858826272906 NA NA hsa04382 Cornified envelope formation 1/27 217/9376 1.60027308414405 S100A9 0.480772533081999 Environmental Information Processing Signal transduction hsa04024 cAMP signaling pathway 1/27 226/9376 1.53654539495247 CGA 0.438768139806514 Human Diseases Infectious disease: viral hsa05163 Human cytomegalovirus infection 1/27 227/9376 1.52977647250775 CCL3 0.434213900541432 Human Diseases Cancer: overview hsa05208 Chemical carcinogenesis - reactive oxygen species 1/27 227/9376 1.52977647250775 SLC25A6 0.434213900541432 Cellular Processes Cell motility hsa04810 Regulation of actin cytoskeleton 1/27 232/9376 1.49680715197957 TMSB4X 0.411764274270893 Organismal Systems Environmental adaptation hsa04714 Thermogenesis 1/27 235/9376 1.47769897557132 RPS6 0.398544047436563 Human Diseases Infectious disease: bacterial hsa05132 Salmonella infection 1/27 248/9376 1.40023894862605 GAPDH 0.343275109332164 Environmental Information Processing Signal transduction hsa04020 Calcium signaling pathway 1/27 254/9376 1.36716243802858 SLC25A6 0.318797575406668 Human Diseases Neurodegenerative disease hsa05012 Parkinson disease 1/27 268/9376 1.29574350469873 SLC25A6 0.263970892984751 Human Diseases Neurodegenerative disease hsa05020 Prion disease 1/27 275/9376 1.26276094276094 SLC25A6 0.237666265202512 Human Diseases Neurodegenerative disease hsa05016 Huntington disease 1/27 308/9376 1.12746512746513 SLC25A6 0.122235098694894 Human Diseases Infectious disease: viral hsa05165 Human papillomavirus infection 1/27 333/9376 1.04282059837615 SPP1 0.0427566355114896 Human Diseases Neurodegenerative disease hsa05022 Pathways of neurodegeneration - multiple diseases 1/27 480/9376 0.723456790123457 SLC25A6 -0.334249811807355