category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Genetic Information Processing	Translation	hsa03010	Ribosome	20/64	222/9376	13.1981981981982	RPS16/MT-RNR2/RPS12/RPS24/RPS29/RPS23/RPS28/RPS25/RPL37A/RPL11/RPL6/RPL26/RPL35A/RPS21/RPL14/RPL38/RPS4X/RPS6/RPL34/RPLP2	15.2482800731233
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	20/64	238/9376	12.3109243697479	RPS16/RPS12/RPS24/RPS29/RPS23/RPS28/RPS25/RPL37A/RPL11/RPL6/C1QB/RPL26/RPL35A/RPS21/RPL14/RPL38/RPS4X/RPS6/RPL34/RPLP2	14.6526151048122
Organismal Systems	Immune system	hsa04612	Antigen processing and presentation	10/64	82/9376	17.8658536585366	CD74/HLA-DRA/IFI30/HLA-DPB1/HLA-B/HLA-DRB1/CTSS/CTSB/HLA-DPA1/HLA-DQA1	12.7165136385442
Human Diseases	Immune disease	hsa05310	Asthma	6/64	32/9376	27.46875	HLA-DRA/HLA-DPB1/HLA-DRB1/HLA-DPA1/FCER1G/HLA-DQA1	12.4335787057236
Human Diseases	Immune disease	hsa05320	Autoimmune thyroid disease	7/64	54/9376	18.9907407407407	HLA-DRA/CGA/HLA-DPB1/HLA-B/HLA-DRB1/HLA-DPA1/HLA-DQA1	10.9912102938675
Human Diseases	Immune disease	hsa05330	Allograft rejection	6/64	39/9376	22.5384615384615	HLA-DRA/HLA-DPB1/HLA-B/HLA-DRB1/HLA-DPA1/HLA-DQA1	11.1737112631808
Human Diseases	Immune disease	hsa05323	Rheumatoid arthritis	8/64	95/9376	12.3368421052632	HLA-DRA/CCL3/HLA-DPB1/HLA-DRB1/CXCL3/CXCL2/HLA-DPA1/HLA-DQA1	9.20684127145677
Human Diseases	Infectious disease: bacterial	hsa05152	Tuberculosis	10/64	181/9376	8.0939226519337	CD74/HLA-DRA/HLA-DPB1/CTSD/HLA-DRB1/CTSS/FCGR3A/HLA-DPA1/FCER1G/HLA-DQA1	7.98921320298229
Human Diseases	Endocrine and metabolic disease	hsa04940	Type I diabetes mellitus	6/64	44/9376	19.9772727272727	HLA-DRA/HLA-DPB1/HLA-B/HLA-DRB1/HLA-DPA1/HLA-DQA1	10.4598850954163
Human Diseases	Immune disease	hsa05332	Graft-versus-host disease	6/64	45/9376	19.5333333333333	HLA-DRA/HLA-DPB1/HLA-B/HLA-DRB1/HLA-DPA1/HLA-DQA1	10.3311779127449
Cellular Processes	Transport and catabolism	hsa04145	Phagosome	9/64	155/9376	8.50645161290323	HLA-DRA/HLA-DPB1/OLR1/HLA-B/HLA-DRB1/CTSS/FCGR3A/HLA-DPA1/HLA-DQA1	7.81206177841719
Human Diseases	Infectious disease: bacterial	hsa05150	Staphylococcus aureus infection	7/64	99/9376	10.3585858585859	HLA-DRA/HLA-DPB1/HLA-DRB1/FCGR3A/C1QB/HLA-DPA1/HLA-DQA1	7.76029426283829
Human Diseases	Cardiovascular disease	hsa05416	Viral myocarditis	6/64	70/9376	12.5571428571429	HLA-DRA/HLA-DPB1/HLA-B/HLA-DRB1/HLA-DPA1/HLA-DQA1	8.04585347094108
Human Diseases	Infectious disease: parasitic	hsa05140	Leishmaniasis	6/64	78/9376	11.2692307692308	HLA-DRA/HLA-DPB1/HLA-DRB1/FCGR3A/HLA-DPA1/HLA-DQA1	7.54995886356634
Organismal Systems	Immune system	hsa04672	Intestinal immune network for IgA production	5/64	50/9376	14.65	HLA-DRA/HLA-DPB1/HLA-DRB1/HLA-DPA1/HLA-DQA1	8.02276533872826
Human Diseases	Immune disease	hsa05322	Systemic lupus erythematosus	7/64	143/9376	7.17132867132867	HLA-DRA/HLA-DPB1/HLA-DRB1/FCGR3A/C1QB/HLA-DPA1/HLA-DQA1	6.16494801871719
Human Diseases	Immune disease	hsa05321	Inflammatory bowel disease	5/64	66/9376	11.0984848484848	HLA-DRA/HLA-DPB1/HLA-DRB1/HLA-DPA1/HLA-DQA1	6.82507592522015
Human Diseases	Infectious disease: viral	hsa05168	Herpes simplex virus 1 infection	7/64	180/9376	5.69722222222222	CD74/HLA-DRA/HLA-DPB1/HLA-B/HLA-DRB1/HLA-DPA1/HLA-DQA1	5.27511606553729
Organismal Systems	Immune system	hsa04658	Th1 and Th2 cell differentiation	5/64	93/9376	7.87634408602151	HLA-DRA/HLA-DPB1/HLA-DRB1/HLA-DPA1/HLA-DQA1	5.52470433450882
Environmental Information Processing	Signaling molecules and interaction	hsa04061	Viral protein interaction with cytokine and cytokine receptor	5/64	100/9376	7.325	CCL3/CCL4/CXCL3/CXCL2/CXCL9	5.2715010991004
Organismal Systems	Immune system	hsa04640	Hematopoietic cell lineage	5/64	100/9376	7.325	HLA-DRA/HLA-DPB1/HLA-DRB1/HLA-DPA1/HLA-DQA1	5.2715010991004
Environmental Information Processing	Signaling molecules and interaction	hsa04514	Cell adhesion molecule (CAM) interaction	6/64	160/9376	5.49375	HLA-DRA/HLA-DPB1/HLA-B/HLA-DRB1/HLA-DPA1/HLA-DQA1	4.75282482246792
Organismal Systems	Immune system	hsa04659	Th17 cell differentiation	5/64	109/9376	6.72018348623853	HLA-DRA/HLA-DPB1/HLA-DRB1/HLA-DPA1/HLA-DQA1	4.97975262110435
Environmental Information Processing	Signaling molecules and interaction	hsa04060	Cytokine-cytokine receptor interaction	8/64	298/9376	3.93288590604027	CCL3/CCL4/CSH2/CSHL1/IL1RN/CXCL3/CXCL2/CXCL9	4.26542542112101
Human Diseases	Infectious disease: parasitic	hsa05145	Toxoplasmosis	5/64	112/9376	6.54017857142857	HLA-DRA/HLA-DPB1/HLA-DRB1/HLA-DPA1/HLA-DQA1	4.88976111817348
Human Diseases	Infectious disease: viral	hsa05169	Epstein-Barr virus infection	6/64	205/9376	4.28780487804878	HLA-DRA/HLA-DPB1/HLA-B/HLA-DRB1/HLA-DPA1/HLA-DQA1	3.94574269200536
Human Diseases	Infectious disease: viral	hsa05166	Human T-cell leukemia virus 1 infection	6/64	224/9376	3.92410714285714	HLA-DRA/HLA-DPB1/HLA-B/HLA-DRB1/HLA-DPA1/HLA-DQA1	3.67209092811965
Environmental Information Processing	Signal transduction	hsa04064	NF-kappa B signaling pathway	4/64	105/9376	5.58095238095238	CCL4/BCL2A1/CXCL3/CXCL2	3.91328319448288
Human Diseases	Infectious disease: viral	hsa05164	Influenza A	5/64	173/9376	4.23410404624277	HLA-DRA/HLA-DPB1/HLA-DRB1/HLA-DPA1/HLA-DQA1	3.5593153686663
Organismal Systems	Immune system	hsa04620	Toll-like receptor signaling pathway	4/64	109/9376	5.37614678899083	SPP1/CCL3/CCL4/CXCL9	3.8096904575249
Organismal Systems	Immune system	hsa04621	NOD-like receptor signaling pathway	5/64	187/9376	3.91711229946524	CASP4/GBP1/CXCL3/CTSB/CXCL2	3.34036532987432
Organismal Systems	Endocrine system	hsa04929	GnRH secretion	3/64	65/9376	6.76153846153846	SPP1/CGA/KISS1	3.86412459989004
Organismal Systems	Immune system	hsa04062	Chemokine signaling pathway	5/64	193/9376	3.79533678756477	CCL3/CCL4/CXCL3/CXCL2/CXCL9	3.25292944664754
Organismal Systems	Immune system	hsa04650	Natural killer cell mediated cytotoxicity	4/64	133/9376	4.40601503759398	TYROBP/HLA-B/FCGR3A/FCER1G	3.27959372322356
Cellular Processes	Cell growth and death	hsa04210	Apoptosis	4/64	137/9376	4.27737226277372	CTSD/BCL2A1/CTSS/CTSB	3.20352203377893
Organismal Systems	Endocrine system	hsa03320	PPAR signaling pathway	3/64	76/9376	5.78289473684211	OLR1/PLIN2/FABP5	3.47064574176478
Organismal Systems	Immune system	hsa04657	IL-17 signaling pathway	3/64	94/9376	4.67553191489362	S100A9/CXCL3/CXCL2	2.96904981579651
Organismal Systems	Endocrine system	hsa04913	Ovarian steroidogenesis	2/64	52/9376	5.63461538461539	CGA/CYP19A1	2.77823117228593
Organismal Systems	Digestive system	hsa04979	Cholesterol metabolism	2/64	52/9376	5.63461538461539	APOC1/APOE	2.77823117228593
Human Diseases	Infectious disease: bacterial	hsa05134	Legionellosis	2/64	56/9376	5.23214285714286	CXCL3/CXCL2	2.63330108372001
Human Diseases	Cardiovascular disease	hsa05417	Lipid and atherosclerosis	4/64	216/9376	2.71296296296296	CCL3/OLR1/CXCL3/CXCL2	2.11145219551344
Environmental Information Processing	Signal transduction	hsa04371	Apelin signaling pathway	3/64	140/9376	3.13928571428571	SPP1/RPS6/ACTA2	2.11419474151495
Organismal Systems	Development and regeneration	hsa04380	Osteoclast differentiation	3/64	142/9376	3.09507042253521	TYROBP/FCGR3A/TREM2	2.08546067224176
Human Diseases	Endocrine and metabolic disease	hsa04936	Alcoholic liver disease	3/64	144/9376	3.05208333333333	CXCL3/C1QB/CXCL2	2.05722826587351
Human Diseases	Infectious disease: bacterial	hsa05120	Epithelial cell signaling in Helicobacter pylori infection	2/64	71/9376	4.12676056338028	CXCL3/CXCL2	2.19239979553055
Cellular Processes	Transport and catabolism	hsa04142	Lysosome biogenesis	4/64	250/9376	2.344	CTSD/LAPTM5/CTSS/CTSB	1.785595909547
Metabolism	Metabolism of cofactors and vitamins	hsa00730	Thiamine metabolism	1/64	15/9376	9.76666666666667	ALPP	2.81691110702417
Organismal Systems	Immune system	hsa04610	Complement and coagulation cascades	2/64	88/9376	3.32954545454545	C1QB/A2M	1.82014322368334
Human Diseases	Infectious disease: viral	hsa05167	Kaposi sarcoma-associated herpesvirus infection	3/64	196/9376	2.24234693877551	HLA-B/CXCL3/CXCL2	1.45714822232175
Human Diseases	Infectious disease: parasitic	hsa05142	Chagas disease	2/64	103/9376	2.84466019417476	CCL3/C1QB	1.56055471525763
Human Diseases	Infectious disease: parasitic	hsa05146	Amoebiasis	2/64	103/9376	2.84466019417476	CXCL3/CXCL2	1.56055471525763
Metabolism	Metabolism of cofactors and vitamins	hsa00790	Folate biosynthesis	1/64	28/9376	5.23214285714286	ALPP	1.85923430645393
NA	NA	hsa04081	Hormone signaling	3/64	219/9376	2.00684931506849	CGA/CSH2/CSHL1	1.24986777477403
Environmental Information Processing	Signal transduction	hsa04668	TNF signaling pathway	2/64	119/9376	2.46218487394958	CXCL3/CXCL2	1.33074479833193
Human Diseases	Infectious disease: viral	hsa05163	Human cytomegalovirus infection	3/64	227/9376	1.93612334801762	CCL3/CCL4/HLA-B	1.18362283050733
Organismal Systems	Endocrine system	hsa04935	Growth hormone synthesis, secretion and action	2/64	122/9376	2.4016393442623	CSH2/CSHL1	1.29183066369116
Environmental Information Processing	Signal transduction	hsa04071	Sphingolipid signaling pathway	2/64	125/9376	2.344	CTSD/FCER1G	1.25404775858306
Environmental Information Processing	Signal transduction	hsa04151	PI3K-Akt signaling pathway	4/64	362/9376	1.61878453038674	SPP1/CSH2/CSHL1/RPS6	0.995380429621115
Environmental Information Processing	Signaling molecules and interaction	hsa04080	Neuroactive ligand-receptor interaction	4/64	370/9376	1.58378378378378	CGA/CSH2/KISS1/CSHL1	0.949819451547468
Cellular Processes	Cell growth and death	hsa04216	Ferroptosis	1/64	42/9376	3.48809523809524	FTL	1.33971336065496
Metabolism	Metabolism of cofactors and vitamins	hsa00860	Porphyrin metabolism	1/64	46/9376	3.18478260869565	FTL	1.2314037323205
Environmental Information Processing	Signal transduction	hsa04630	JAK-STAT signaling pathway	2/64	168/9376	1.74404761904762	CSH2/CSHL1	0.806727494056962
Cellular Processes	Transport and catabolism	hsa04140	Autophagy - animal	2/64	169/9376	1.73372781065089	CTSD/CTSB	0.797945817755563
Organismal Systems	Endocrine system	hsa04923	Regulation of lipolysis in adipocytes	1/64	59/9376	2.48305084745763	CGA	0.947323129464126
Organismal Systems	Digestive system	hsa04978	Mineral absorption	1/64	61/9376	2.4016393442623	FTL	0.910466370635461
Metabolism	Lipid metabolism	hsa00140	Steroid hormone biosynthesis	1/64	66/9376	2.21969696969697	CYP19A1	0.8243340014707
Human Diseases	Cancer: specific types	hsa05221	Acute myeloid leukemia	1/64	68/9376	2.15441176470588	BCL2A1	0.792029129717887
Organismal Systems	Immune system	hsa04664	Fc epsilon RI signaling pathway	1/64	69/9376	2.1231884057971	FCER1G	0.77629437933808
Organismal Systems	Endocrine system	hsa04924	Renin secretion	1/64	69/9376	2.1231884057971	CTSB	0.77629437933808
Organismal Systems	Immune system	hsa04613	Neutrophil extracellular trap formation	2/64	195/9376	1.5025641025641	CASP4/FCGR3A	0.587919571519299
Organismal Systems	Endocrine system	hsa04917	Prolactin signaling pathway	1/64	71/9376	2.06338028169014	CGA	0.745613443975479
Organismal Systems	Endocrine system	hsa04918	Thyroid hormone synthesis	1/64	75/9376	1.95333333333333	CGA	0.687170851818105
Human Diseases	Infectious disease: bacterial	hsa05133	Pertussis	1/64	78/9376	1.87820512820513	C1QB	0.645658154999119
Human Diseases	Drug resistance: antineoplastic	hsa01521	EGFR tyrosine kinase inhibitor resistance	1/64	80/9376	1.83125	RPS6	0.618988721421421
Organismal Systems	Immune system	hsa04623	Cytosolic DNA-sensing pathway	1/64	83/9376	1.76506024096386	CCL4	0.580377880395076
Environmental Information Processing	Signaling molecules and interaction	hsa04512	ECM-receptor interaction	1/64	89/9376	1.64606741573034	SPP1	0.507679071103838
Organismal Systems	Endocrine system	hsa04912	GnRH signaling pathway	1/64	93/9376	1.5752688172043	CGA	0.462191840338111
Organismal Systems	Digestive system	hsa04970	Salivary secretion	1/64	93/9376	1.5752688172043	LYZ	0.462191840338111
Organismal Systems	Immune system	hsa04666	Fc gamma R-mediated phagocytosis	1/64	98/9376	1.49489795918367	FCGR3A	0.408277698741442
Organismal Systems	Endocrine system	hsa04925	Aldosterone synthesis and secretion	1/64	98/9376	1.49489795918367	NR4A2	0.408277698741442
Organismal Systems	Immune system	hsa04625	C-type lectin receptor signaling pathway	1/64	105/9376	1.3952380952381	FCER1G	0.337632541727733
Environmental Information Processing	Signal transduction	hsa04066	HIF-1 signaling pathway	1/64	110/9376	1.33181818181818	RPS6	0.290204749263293
Organismal Systems	Endocrine system	hsa04928	Parathyroid hormone synthesis, secretion and action	1/64	115/9376	1.27391304347826	NR4A2	0.245011705305475
Organismal Systems	Immune system	hsa04611	Platelet activation	1/64	126/9376	1.16269841269841	FCER1G	0.152423476781477
Organismal Systems	Endocrine system	hsa04926	Relaxin signaling pathway	1/64	130/9376	1.12692307692308	ACTA2	0.120806267145719
Organismal Systems	Circulatory system	hsa04270	Vascular smooth muscle contraction	1/64	134/9376	1.09328358208955	ACTA2	0.0901630871296143
Organismal Systems	Endocrine system	hsa04910	Insulin signaling pathway	1/64	138/9376	1.06159420289855	RPS6	0.0604288800094968
Organismal Systems	Endocrine system	hsa04915	Estrogen signaling pathway	1/64	139/9376	1.05395683453237	CTSD	0.0531303323989724
Environmental Information Processing	Signal transduction	hsa04072	Phospholipase D signaling pathway	1/64	149/9376	0.983221476510067	FCER1G	-0.0171147577256371
Metabolism	Global and overview maps	hsa01240	Biosynthesis of cofactors	1/64	154/9376	0.951298701298701	ALPP	-0.0505175739143443
NA	NA	hsa04518	Integrin signaling	1/64	154/9376	0.951298701298701	SPP1	-0.0505175739143443
Cellular Processes	Transport and catabolism	hsa04148	Efferocytosis	1/64	157/9376	0.93312101910828	C1QB	-0.0700570275865464
Cellular Processes	Cell growth and death	hsa04218	Cellular senescence	1/64	157/9376	0.93312101910828	HLA-B	-0.0700570275865464
Environmental Information Processing	Signal transduction	hsa04150	mTOR signaling pathway	1/64	158/9376	0.927215189873418	RPS6	-0.0764900749585073
Human Diseases	Infectious disease: viral	hsa05165	Human papillomavirus infection	2/64	333/9376	0.87987987987988	SPP1/HLA-B	-0.185027274112883
Cellular Processes	Cell growth and death	hsa04217	Necroptosis	1/64	168/9376	0.872023809523809	FTL	-0.138757128977797
Cellular Processes	Cell motility	hsa04814	Motor proteins	1/64	194/9376	0.755154639175258	ACTA2	-0.285678950674668
Human Diseases	Infectious disease: bacterial	hsa05130	Pathogenic Escherichia coli infection	1/64	200/9376	0.7325	CASP4	-0.317005081056748
Human Diseases	Cancer: overview	hsa05202	Transcriptional misregulation in cancer	1/64	201/9376	0.728855721393035	BCL2A1	-0.322143652640988
Cellular Processes	Cellular community - eukaryotes	hsa04510	Focal adhesion	1/64	203/9376	0.721674876847291	SPP1	-0.332352441613176
Human Diseases	Cancer: overview	hsa05205	Proteoglycans in cancer	1/64	204/9376	0.718137254901961	RPS6	-0.33742315314057
Human Diseases	Cancer: overview	hsa05203	Viral carcinogenesis	1/64	205/9376	0.714634146341463	HLA-B	-0.342471732169604
Human Diseases	Cardiovascular disease	hsa05415	Diabetic cardiomyopathy	1/64	205/9376	0.714634146341463	CTSD	-0.342471732169604
Human Diseases	Infectious disease: viral	hsa05170	Human immunodeficiency virus 1 infection	1/64	214/9376	0.684579439252336	HLA-B	-0.38695092037073
NA	NA	hsa04382	Cornified envelope formation	1/64	217/9376	0.675115207373272	S100A9	-0.40141108564896
Environmental Information Processing	Signal transduction	hsa04024	cAMP signaling pathway	1/64	226/9376	0.648230088495575	CGA	-0.443768532804952
Organismal Systems	Environmental adaptation	hsa04714	Thermogenesis	1/64	235/9376	0.623404255319149	RPS6	-0.484692864957937
Human Diseases	Infectious disease: bacterial	hsa05132	Salmonella infection	1/64	248/9376	0.590725806451613	CASP4	-0.541510058067665
Cellular Processes	Transport and catabolism	hsa04144	Endocytosis	1/64	250/9376	0.586	HLA-B	-0.55002731142296
Human Diseases	Infectious disease: bacterial	hsa05131	Shigellosis	1/64	253/9376	0.579051383399209	CASP4	-0.562697066804147
Human Diseases	Neurodegenerative disease	hsa05020	Prion disease	1/64	275/9376	0.532727272727273	C1QB	-0.651998152483895
Human Diseases	Neurodegenerative disease	hsa05010	Alzheimer disease	1/64	388/9376	0.377577319587629	APOE	-1.03806340712671