ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0045296 cadherin binding 28/361 334/18639 0.0838323353293413 4.32839583989915 8.50528212039717e-11 5.54544394249895e-08 GO:0003735 structural constituent of ribosome 14/361 175/18639 0.08 4.13052631578947 8.2791409926523e-06 0.00269899996360465 GO:0003712 transcription coregulator activity 23/361 495/18639 0.0464646464646465 2.39904306220096 0.000106642047824926 0.0175159006804916 GO:0044548 S100 protein binding 4/361 14/18639 0.285714285714286 14.7518796992481 0.000118790285001441 0.0175159006804916 GO:0008201 heparin binding 12/361 172/18639 0.0697674418604651 3.60220318237454 0.000136867720365973 0.0175159006804916 GO:0003779 actin binding 21/361 443/18639 0.0474040632054176 2.44754663181656 0.000161189270065874 0.0175159006804916 GO:0005539 glycosaminoglycan binding 14/361 242/18639 0.0578512396694215 2.98695084819487 0.000281031663218189 0.0261760920597514 GO:0005201 extracellular matrix structural constituent 11/361 168/18639 0.0654761904761905 3.38063909774436 0.000444943577125354 0.0362629015357163 GO:0004864 protein phosphatase inhibitor activity 6/361 53/18639 0.113207547169811 5.84508440913605 0.000539542267307906 0.036407918148924 GO:0003714 transcription corepressor activity 12/361 204/18639 0.0588235294117647 3.03715170278638 0.000651342512752442 0.036407918148924 GO:0098632 cell-cell adhesion mediator activity 6/361 55/18639 0.109090909090909 5.63253588516746 0.000659579152611625 0.036407918148924 GO:0098631 cell adhesion mediator activity 7/361 76/18639 0.0921052631578947 4.75554016620499 0.000670084383109031 0.036407918148924 GO:0019212 phosphatase inhibitor activity 6/361 56/18639 0.107142857142857 5.53195488721804 0.000726858657309363 0.036454757274285 GO:1901681 sulfur compound binding 14/361 275/18639 0.0509090909090909 2.62851674641148 0.000996108646971663 0.0463902027018231 GO:0004857 enzyme inhibitor activity 18/361 416/18639 0.0432692307692308 2.23405870445344 0.00133228227470318 0.0579098695404314 GO:0003743 translation initiation factor activity 5/361 51/18639 0.0980392156862745 5.06191950464396 0.00299955504016138 0.118951537531781 GO:0031491 nucleosome binding 6/361 74/18639 0.0810810810810811 4.18634423897582 0.00310149714423356 0.118951537531781 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 3/361 16/18639 0.1875 9.68092105263158 0.00334523977352744 0.121172018463327 GO:0015035 protein-disulfide reductase activity 4/361 34/18639 0.117647058823529 6.07430340557276 0.00405642716272297 0.139199500531335 GO:0098641 cadherin binding involved in cell-cell adhesion 3/361 18/18639 0.166666666666667 8.60526315789474 0.00473682547470654 0.154420510475433 GO:0008135 translation factor activity, RNA binding 6/361 83/18639 0.072289156626506 3.73240329740013 0.00546904286301434 0.164307358744407 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 3/361 19/18639 0.157894736842105 8.15235457063712 0.00554509907986344 0.164307358744407 GO:0180051 translation factor activity 6/361 84/18639 0.0714285714285714 3.68796992481203 0.00579611848331499 0.164307358744407 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 3/361 20/18639 0.15 7.74473684210526 0.00643109503288716 0.168545989356455 GO:0019905 syntaxin binding 5/361 61/18639 0.0819672131147541 4.2320966350302 0.00649445558255915 0.168545989356455 GO:0001221 transcription coregulator binding 7/361 115/18639 0.0608695652173913 3.14279176201373 0.00709085648642093 0.168545989356455 GO:0140297 DNA-binding transcription factor binding 18/361 488/18639 0.0368852459016393 1.90444348576359 0.00712252861832345 0.168545989356455 GO:0015036 disulfide oxidoreductase activity 4/361 40/18639 0.1 5.16315789473684 0.00730043482214613 0.168545989356455 GO:0043021 ribonucleoprotein complex binding 9/361 177/18639 0.0508474576271186 2.62533452274755 0.0077328999902129 0.168545989356455 GO:0051015 actin filament binding 10/361 209/18639 0.0478468899521531 2.47041047595064 0.0077551835593461 0.168545989356455 GO:0031683 G-protein beta/gamma-subunit complex binding 3/361 22/18639 0.136363636363636 7.04066985645933 0.008443230939435 0.177580212016504 GO:0042393 histone binding 11/361 247/18639 0.0445344129554656 2.29938205838483 0.00898816382954941 0.183133838027069 GO:0048027 mRNA 5'-UTR binding 3/361 24/18639 0.125 6.45394736842105 0.0107852823133573 0.213091032373 GO:0140658 ATP-dependent chromatin remodeler activity 8/361 158/18639 0.0506329113924051 2.61425716189207 0.0119999239003467 0.225089080631434 GO:0042974 nuclear retinoic acid receptor binding 3/361 25/18639 0.12 6.19578947368421 0.0120830027946322 0.225089080631434 GO:0008143 poly(A) binding 3/361 26/18639 0.115384615384615 5.95748987854251 0.0134664393562988 0.237300498927211 GO:0034237 protein kinase A regulatory subunit binding 3/361 26/18639 0.115384615384615 5.95748987854251 0.0134664393562988 0.237300498927211 GO:0035064 methylated histone binding 5/361 74/18639 0.0675675675675676 3.48862019914651 0.0143612316766504 0.246408501399371 GO:0015924 mannosyl-oligosaccharide mannosidase activity 2/361 10/18639 0.2 10.3263157894737 0.0151896068302733 0.247414046333661 GO:0140034 methylation-dependent protein binding 5/361 76/18639 0.0657894736842105 3.39681440443213 0.015967382236367 0.247414046333661 GO:0016887 ATP hydrolysis activity 15/361 417/18639 0.0359712230215827 1.85725104127225 0.0164293206689523 0.247414046333661 GO:0003724 RNA helicase activity 5/361 77/18639 0.0649350649350649 3.3526999316473 0.0168135494253428 0.247414046333661 GO:0016922 nuclear receptor binding 7/361 137/18639 0.0510948905109489 2.6381098732232 0.0174251638410129 0.247414046333661 GO:0019888 protein phosphatase regulator activity 6/361 107/18639 0.0560747663551402 2.89522872602066 0.0178597196904157 0.247414046333661 GO:0004629 phospholipase C activity 3/361 29/18639 0.103448275862069 5.34119782214156 0.018137754940967 0.247414046333661 GO:0043522 leucine zipper domain binding 2/361 11/18639 0.181818181818182 9.38755980861244 0.0183297201056613 0.247414046333661 GO:0045294 alpha-catenin binding 2/361 11/18639 0.181818181818182 9.38755980861244 0.0183297201056613 0.247414046333661 GO:0070990 snRNP binding 2/361 11/18639 0.181818181818182 9.38755980861244 0.0183297201056613 0.247414046333661 GO:0008186 ATP-dependent activity, acting on RNA 5/361 79/18639 0.0632911392405063 3.26782145236509 0.0185940004146463 0.247414046333661 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 13/361 349/18639 0.0372492836676218 1.92323933041773 0.0190338384781474 0.248201253755042 GO:0001968 fibronectin binding 3/361 30/18639 0.1 5.16315789473684 0.0198700550067219 0.251869646592543 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 4/361 54/18639 0.0740740740740741 3.82456140350877 0.0204740663641178 0.251869646592543 GO:0017069 snRNA binding 4/361 54/18639 0.0740740740740741 3.82456140350877 0.0204740663641178 0.251869646592543 GO:0030246 carbohydrate binding 11/361 280/18639 0.0392857142857143 2.02838345864662 0.021051503998591 0.254177418649654 GO:0070717 poly-purine tract binding 3/361 32/18639 0.09375 4.84046052631579 0.0235988170360446 0.279753249227293 GO:0086080 protein binding involved in heterotypic cell-cell adhesion 2/361 13/18639 0.153846153846154 7.94331983805668 0.0253415687288931 0.287726613854567 GO:0140666 annealing activity 2/361 13/18639 0.153846153846154 7.94331983805668 0.0253415687288931 0.287726613854567 GO:0071889 14-3-3 protein binding 3/361 33/18639 0.0909090909090909 4.69377990430622 0.0255953122754063 0.287726613854567 GO:0019208 phosphatase regulator activity 6/361 117/18639 0.0512820512820513 2.64777327935223 0.0263839094562984 0.291564558737399 GO:0008376 acetylgalactosaminyltransferase activity 3/361 34/18639 0.0882352941176471 4.55572755417957 0.0276797205121176 0.296772113022283 GO:0004197 cysteine-type endopeptidase activity 5/361 88/18639 0.0568181818181818 2.93361244019139 0.0281276513308792 0.296772113022283 GO:0008494 translation activator activity 2/361 14/18639 0.142857142857143 7.37593984962406 0.0291922088565492 0.296772113022283 GO:0043176 amine binding 2/361 14/18639 0.142857142857143 7.37593984962406 0.0291922088565492 0.296772113022283 GO:0003727 single-stranded RNA binding 5/361 89/18639 0.0561797752808989 2.90065050266115 0.0293466215071047 0.296772113022283 GO:0008234 cysteine-type peptidase activity 8/361 187/18639 0.0427807486631016 2.20883760202646 0.0295861769117306 0.296772113022283 GO:0051082 unfolded protein binding 6/361 121/18639 0.0495867768595041 2.56024358416703 0.0304392236684987 0.300702633816078 GO:0004386 helicase activity 7/361 155/18639 0.0451612903225806 2.33174872665535 0.0315237005932828 0.301179817692804 GO:0004559 alpha-mannosidase activity 2/361 15/18639 0.133333333333333 6.88421052631579 0.0332591209722115 0.301179817692804 GO:0005523 tropomyosin binding 2/361 15/18639 0.133333333333333 6.88421052631579 0.0332591209722115 0.301179817692804 GO:0042809 nuclear vitamin D receptor binding 2/361 15/18639 0.133333333333333 6.88421052631579 0.0332591209722115 0.301179817692804 GO:0045504 dynein heavy chain binding 2/361 15/18639 0.133333333333333 6.88421052631579 0.0332591209722115 0.301179817692804 GO:0051371 muscle alpha-actinin binding 2/361 15/18639 0.133333333333333 6.88421052631579 0.0332591209722115 0.301179817692804 GO:0042805 actinin binding 3/361 37/18639 0.0810810810810811 4.18634423897582 0.0344574127108768 0.307756617636873 GO:0019843 rRNA binding 4/361 65/18639 0.0615384615384615 3.17732793522267 0.0372165834857338 0.313733477396915 GO:0004867 serine-type endopeptidase inhibitor activity 5/361 95/18639 0.0526315789473684 2.71745152354571 0.0373576532756909 0.313733477396915 GO:0005159 insulin-like growth factor receptor binding 2/361 16/18639 0.125 6.45394736842105 0.0375325325720235 0.313733477396915 GO:0015923 mannosidase activity 2/361 16/18639 0.125 6.45394736842105 0.0375325325720235 0.313733477396915 GO:0030275 LRR domain binding 2/361 16/18639 0.125 6.45394736842105 0.0375325325720235 0.313733477396915 GO:0050840 extracellular matrix binding 4/361 67/18639 0.0597014925373134 3.08248232521603 0.0409043946538973 0.333974808675885 GO:0051787 misfolded protein binding 2/361 17/18639 0.117647058823529 6.07430340557276 0.0420029667353107 0.333974808675885 GO:0070492 oligosaccharide binding 2/361 17/18639 0.117647058823529 6.07430340557276 0.0420029667353107 0.333974808675885 GO:1990226 histone methyltransferase binding 2/361 17/18639 0.117647058823529 6.07430340557276 0.0420029667353107 0.333974808675885 GO:0005179 hormone activity 6/361 132/18639 0.0454545454545455 2.34688995215311 0.0436216439937023 0.342666408239686 GO:0031492 nucleosomal DNA binding 3/361 42/18639 0.0714285714285714 3.68796992481203 0.0474703024792975 0.368459966863119 GO:0019838 growth factor binding 6/361 136/18639 0.0441176470588235 2.27786377708978 0.0491792531765003 0.377233800836214 GO:0008094 ATP-dependent activity, acting on DNA 8/361 210/18639 0.0380952380952381 1.96691729323308 0.0524255299124783 0.397458668638789 GO:0030547 signaling receptor inhibitor activity 3/361 44/18639 0.0681818181818182 3.52033492822966 0.0532590680749439 0.399136923963947 GO:0000149 SNARE binding 5/361 106/18639 0.0471698113207547 2.43545183714002 0.0552291533122083 0.409197817722271 GO:0031418 L-ascorbic acid binding 2/361 20/18639 0.1 5.16315789473684 0.0565059080881833 0.409743868864015 GO:0046982 protein heterodimerization activity 12/361 369/18639 0.032520325203252 1.6790757381258 0.056559736499634 0.409743868864015 GO:0003725 double-stranded RNA binding 4/361 75/18639 0.0533333333333333 2.75368421052632 0.0576500046042349 0.413052780241331 GO:0003713 transcription coactivator activity 9/361 256/18639 0.03515625 1.81517269736842 0.0621839582099458 0.440695008183529 GO:0140693 molecular condensate scaffold activity 3/361 48/18639 0.0625 3.22697368421053 0.0657945524584452 0.456430840607738 GO:0005200 structural constituent of cytoskeleton 5/361 112/18639 0.0446428571428571 2.30498120300752 0.0667380654509959 0.456430840607738 GO:0043022 ribosome binding 5/361 112/18639 0.0446428571428571 2.30498120300752 0.0667380654509959 0.456430840607738 GO:0046332 SMAD binding 4/361 79/18639 0.0506329113924051 2.61425716189207 0.0672045409483785 0.456430840607738 GO:0048306 calcium-dependent protein binding 4/361 80/18639 0.05 2.58157894736842 0.0697137788945433 0.462374964532889 GO:0004602 glutathione peroxidase activity 2/361 23/18639 0.0869565217391304 4.48970251716247 0.0724676719020853 0.462374964532889 GO:0017134 fibroblast growth factor binding 2/361 23/18639 0.0869565217391304 4.48970251716247 0.0724676719020853 0.462374964532889 GO:0140597 protein carrier chaperone 7/361 188/18639 0.0372340425531915 1.92245240761478 0.0737517375735516 0.462374964532889 GO:0000510 H3-H4 histone complex chaperone activity 6/361 151/18639 0.0397350993377483 2.05158591843848 0.073753061827332 0.462374964532889 GO:0140584 chromatin extrusion motor activity 6/361 151/18639 0.0397350993377483 2.05158591843848 0.073753061827332 0.462374964532889 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 6/361 151/18639 0.0397350993377483 2.05158591843848 0.073753061827332 0.462374964532889 GO:0140849 ATP-dependent H2AZ histone chaperone activity 6/361 151/18639 0.0397350993377483 2.05158591843848 0.073753061827332 0.462374964532889 GO:0015616 DNA translocase activity 6/361 152/18639 0.0394736842105263 2.03808864265928 0.0756017101180534 0.463092015694531 GO:0140674 ATP-dependent histone chaperone activity 6/361 152/18639 0.0394736842105263 2.03808864265928 0.0756017101180534 0.463092015694531 GO:0005048 signal sequence binding 3/361 51/18639 0.0588235294117647 3.03715170278638 0.0759982295695013 0.463092015694531 GO:0061775 cohesin loader activity 6/361 153/18639 0.0392156862745098 2.02476780185758 0.0774765311460742 0.467018399410847 GO:0030215 semaphorin receptor binding 2/361 24/18639 0.0833333333333333 4.30263157894737 0.0780751618646969 0.467018399410847 GO:0005080 protein kinase C binding 3/361 52/18639 0.0576923076923077 2.97874493927126 0.0795455570724634 0.471488211011328 GO:0051018 protein kinase A binding 3/361 53/18639 0.0566037735849057 2.92254220456802 0.0831637204325299 0.484131658232227 GO:1901505 carbohydrate derivative transmembrane transporter activity 3/361 53/18639 0.0566037735849057 2.92254220456802 0.0831637204325299 0.484131658232227 GO:0050750 low-density lipoprotein particle receptor binding 2/361 26/18639 0.0769230769230769 3.97165991902834 0.0896758747397506 0.51288307307296 GO:0070412 R-SMAD binding 2/361 26/18639 0.0769230769230769 3.97165991902834 0.0896758747397506 0.51288307307296 GO:0003689 DNA clamp loader activity 6/361 160/18639 0.0375 1.93618421052632 0.0913277194023245 0.517788461307092 GO:0008083 growth factor activity 6/361 162/18639 0.037037037037037 1.91228070175439 0.0955165450530031 0.533052005709185 GO:0008320 protein transmembrane transporter activity 2/361 27/18639 0.0740740740740741 3.82456140350877 0.095655037834317 0.533052005709185 GO:0140713 histone chaperone activity 6/361 164/18639 0.0365853658536585 1.88896020539153 0.0998066939516231 0.546548098690961 GO:0045499 chemorepellent activity 2/361 28/18639 0.0714285714285714 3.68796992481203 0.101744403105396 0.546548098690961 GO:0046966 nuclear thyroid hormone receptor binding 2/361 28/18639 0.0714285714285714 3.68796992481203 0.101744403105396 0.546548098690961 GO:0051393 alpha-actinin binding 2/361 28/18639 0.0714285714285714 3.68796992481203 0.101744403105396 0.546548098690961 GO:0061980 regulatory RNA binding 3/361 58/18639 0.0517241379310345 2.67059891107078 0.102268202515793 0.546548098690961 GO:0031490 chromatin DNA binding 5/361 128/18639 0.0390625 2.01685855263158 0.103379076452253 0.547993153226579 GO:0001786 phosphatidylserine binding 3/361 59/18639 0.0508474576271186 2.62533452274755 0.10628175677139 0.55853366886355 GO:0003785 actin monomer binding 2/361 29/18639 0.0689655172413793 3.56079854809437 0.107937488154612 0.55853366886355 GO:0043236 laminin binding 2/361 29/18639 0.0689655172413793 3.56079854809437 0.107937488154612 0.55853366886355 GO:0001965 G-protein alpha-subunit binding 2/361 30/18639 0.0666666666666667 3.44210526315789 0.114228019093748 0.574209896115492 GO:0035925 mRNA 3'-UTR AU-rich region binding 2/361 30/18639 0.0666666666666667 3.44210526315789 0.114228019093748 0.574209896115492 GO:0048019 receptor antagonist activity 2/361 30/18639 0.0666666666666667 3.44210526315789 0.114228019093748 0.574209896115492 GO:0015026 coreceptor activity 3/361 61/18639 0.0491803278688525 2.53925798101812 0.114489703213212 0.574209896115492 GO:0140030 modification-dependent protein binding 6/361 173/18639 0.0346820809248555 1.7906905993307 0.120337779271482 0.574744704745088 GO:0070325 lipoprotein particle receptor binding 2/361 31/18639 0.0645161290322581 3.33106960950764 0.120609924936816 0.574744704745088 GO:0005507 copper ion binding 3/361 63/18639 0.0476190476190476 2.45864661654135 0.122928709958007 0.574744704745088 GO:0022884 macromolecule transmembrane transporter activity 2/361 32/18639 0.0625 3.22697368421053 0.127077332130201 0.574744704745088 GO:0031369 translation initiation factor binding 2/361 32/18639 0.0625 3.22697368421053 0.127077332130201 0.574744704745088 GO:0140311 protein sequestering activity 2/361 33/18639 0.0606060606060606 3.12918660287081 0.133624559217608 0.574744704745088 GO:0051427 hormone receptor binding 2/361 34/18639 0.0588235294117647 3.03715170278638 0.140246111636701 0.574744704745088 GO:0003777 microtubule motor activity 3/361 68/18639 0.0441176470588235 2.27786377708978 0.144957007923687 0.574744704745088 GO:1990841 promoter-specific chromatin binding 3/361 68/18639 0.0441176470588235 2.27786377708978 0.144957007923687 0.574744704745088 GO:0140566 histone reader activity 2/361 35/18639 0.0571428571428571 2.95037593984962 0.146936676644345 0.574744704745088 GO:0061135 endopeptidase regulator activity 6/361 184/18639 0.0326086956521739 1.68363844393593 0.148020463899914 0.574744704745088 GO:0019955 cytokine binding 5/361 144/18639 0.0347222222222222 1.79276315789474 0.14802359669407 0.574744704745088 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 13/361 484/18639 0.0268595041322314 1.38679860809047 0.148164826889774 0.574744704745088 GO:0061134 peptidase regulator activity 7/361 226/18639 0.0309734513274336 1.59920819748486 0.15035070449309 0.574744704745088 GO:0005484 SNAP receptor activity 2/361 36/18639 0.0555555555555556 2.86842105263158 0.153691118367435 0.574744704745088 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 2/361 36/18639 0.0555555555555556 2.86842105263158 0.153691118367435 0.574744704745088 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 2/361 36/18639 0.0555555555555556 2.86842105263158 0.153691118367435 0.574744704745088 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 2/361 36/18639 0.0555555555555556 2.86842105263158 0.153691118367435 0.574744704745088 GO:0097110 scaffold protein binding 3/361 70/18639 0.0428571428571429 2.21278195488722 0.154108418465673 0.574744704745088 GO:0004843 cysteine-type deubiquitinase activity 4/361 108/18639 0.037037037037037 1.91228070175439 0.157602044676038 0.574744704745088 GO:0001216 DNA-binding transcription activator activity 13/361 491/18639 0.0264765784114053 1.36702754850466 0.159468084518981 0.574744704745088 GO:0043394 proteoglycan binding 2/361 37/18639 0.0540540540540541 2.79089615931721 0.160504472976381 0.574744704745088 GO:0005518 collagen binding 3/361 72/18639 0.0416666666666667 2.15131578947368 0.163435775987602 0.574744704745088 GO:0004175 endopeptidase activity 11/361 405/18639 0.0271604938271605 1.40233918128655 0.164633072173742 0.574744704745088 GO:0004222 metalloendopeptidase activity 4/361 110/18639 0.0363636363636364 1.87751196172249 0.165006578126239 0.574744704745088 GO:0042162 telomeric DNA binding 2/361 38/18639 0.0526315789473684 2.71745152354571 0.167371943978375 0.574744704745088 GO:0043539 protein serine/threonine kinase activator activity 3/361 73/18639 0.0410958904109589 2.12184571016583 0.168161626513384 0.574744704745088 GO:0008017 microtubule binding 8/361 276/18639 0.0289855072463768 1.49656750572082 0.168461293740874 0.574744704745088 GO:0048029 monosaccharide binding 3/361 74/18639 0.0405405405405405 2.09317211948791 0.172926906151661 0.574744704745088 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 2/361 39/18639 0.0512820512820513 2.64777327935223 0.174288897627623 0.574744704745088 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 2/361 39/18639 0.0512820512820513 2.64777327935223 0.174288897627623 0.574744704745088 GO:0001164 RNA polymerase I core promoter sequence-specific DNA binding 1/361 10/18639 0.1 5.16315789473684 0.177681746294724 0.574744704745088 GO:0004955 prostaglandin receptor activity 1/361 10/18639 0.1 5.16315789473684 0.177681746294724 0.574744704745088 GO:0005131 growth hormone receptor binding 1/361 10/18639 0.1 5.16315789473684 0.177681746294724 0.574744704745088 GO:0005381 iron ion transmembrane transporter activity 1/361 10/18639 0.1 5.16315789473684 0.177681746294724 0.574744704745088 GO:0008140 cAMP response element binding protein binding 1/361 10/18639 0.1 5.16315789473684 0.177681746294724 0.574744704745088 GO:0008190 eukaryotic initiation factor 4E binding 1/361 10/18639 0.1 5.16315789473684 0.177681746294724 0.574744704745088 GO:0015187 glycine transmembrane transporter activity 1/361 10/18639 0.1 5.16315789473684 0.177681746294724 0.574744704745088 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen 1/361 10/18639 0.1 5.16315789473684 0.177681746294724 0.574744704745088 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines 1/361 10/18639 0.1 5.16315789473684 0.177681746294724 0.574744704745088 GO:0035374 chondroitin sulfate binding 1/361 10/18639 0.1 5.16315789473684 0.177681746294724 0.574744704745088 GO:0050815 phosphoserine residue binding 1/361 10/18639 0.1 5.16315789473684 0.177681746294724 0.574744704745088 GO:0051880 G-quadruplex DNA binding 1/361 10/18639 0.1 5.16315789473684 0.177681746294724 0.574744704745088 GO:0140999 histone H3K4 trimethyltransferase activity 1/361 10/18639 0.1 5.16315789473684 0.177681746294724 0.574744704745088 GO:0015144 carbohydrate transmembrane transporter activity 2/361 40/18639 0.05 2.58157894736842 0.181250858449811 0.574744704745088 GO:0017022 myosin binding 3/361 76/18639 0.0394736842105263 2.03808864265928 0.182569743445924 0.574744704745088 GO:0101005 deubiquitinase activity 4/361 115/18639 0.0347826086956522 1.79588100686499 0.184040966987355 0.574744704745088 GO:0016758 hexosyltransferase activity 6/361 197/18639 0.0304568527918782 1.57253539941224 0.184050530624829 0.574744704745088 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 2/361 41/18639 0.0487804878048781 2.5186136071887 0.188253504878097 0.574744704745088 GO:0140318 protein transporter activity 2/361 41/18639 0.0487804878048781 2.5186136071887 0.188253504878097 0.574744704745088 GO:0019199 transmembrane receptor protein kinase activity 3/361 78/18639 0.0384615384615385 1.98582995951417 0.19235236208345 0.574744704745088 GO:0000014 single-stranded DNA endodeoxyribonuclease activity 1/361 11/18639 0.0909090909090909 4.69377990430622 0.19361694891363 0.574744704745088 GO:0001163 RNA polymerase I transcription regulatory region sequence-specific DNA binding 1/361 11/18639 0.0909090909090909 4.69377990430622 0.19361694891363 0.574744704745088 GO:0003953 NAD+ nucleosidase activity 1/361 11/18639 0.0909090909090909 4.69377990430622 0.19361694891363 0.574744704745088 GO:0004954 prostanoid receptor activity 1/361 11/18639 0.0909090909090909 4.69377990430622 0.19361694891363 0.574744704745088 GO:0005225 volume-sensitive anion channel activity 1/361 11/18639 0.0909090909090909 4.69377990430622 0.19361694891363 0.574744704745088 GO:0005536 D-glucose binding 1/361 11/18639 0.0909090909090909 4.69377990430622 0.19361694891363 0.574744704745088 GO:0008432 JUN kinase binding 1/361 11/18639 0.0909090909090909 4.69377990430622 0.19361694891363 0.574744704745088 GO:0010854 adenylate cyclase regulator activity 1/361 11/18639 0.0909090909090909 4.69377990430622 0.19361694891363 0.574744704745088 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity 1/361 11/18639 0.0909090909090909 4.69377990430622 0.19361694891363 0.574744704745088 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 1/361 11/18639 0.0909090909090909 4.69377990430622 0.19361694891363 0.574744704745088 GO:0019206 nucleoside kinase activity 1/361 11/18639 0.0909090909090909 4.69377990430622 0.19361694891363 0.574744704745088 GO:0019215 intermediate filament binding 1/361 11/18639 0.0909090909090909 4.69377990430622 0.19361694891363 0.574744704745088 GO:0048185 activin binding 1/361 11/18639 0.0909090909090909 4.69377990430622 0.19361694891363 0.574744704745088 GO:0050786 RAGE receptor binding 1/361 11/18639 0.0909090909090909 4.69377990430622 0.19361694891363 0.574744704745088 GO:0097493 structural molecule activity conferring elasticity 1/361 11/18639 0.0909090909090909 4.69377990430622 0.19361694891363 0.574744704745088 GO:1990948 ubiquitin ligase inhibitor activity 1/361 11/18639 0.0909090909090909 4.69377990430622 0.19361694891363 0.574744704745088 GO:0008307 structural constituent of muscle 2/361 42/18639 0.0476190476190476 2.45864661654135 0.195292664998037 0.574744704745088 GO:0016859 cis-trans isomerase activity 2/361 42/18639 0.0476190476190476 2.45864661654135 0.195292664998037 0.574744704745088 GO:0035198 miRNA binding 2/361 42/18639 0.0476190476190476 2.45864661654135 0.195292664998037 0.574744704745088 GO:0008200 ion channel inhibitor activity 2/361 43/18639 0.0465116279069767 2.40146878824969 0.202364312398855 0.574744704745088 GO:0004866 endopeptidase inhibitor activity 5/361 161/18639 0.031055900621118 1.60346518470088 0.202779215809534 0.574744704745088 GO:0005178 integrin binding 5/361 161/18639 0.031055900621118 1.60346518470088 0.202779215809534 0.574744704745088 GO:0140097 catalytic activity, acting on DNA 9/361 336/18639 0.0267857142857143 1.38298872180451 0.205935672133833 0.574744704745088 GO:0003697 single-stranded DNA binding 4/361 121/18639 0.0330578512396694 1.70682905611135 0.207766379674252 0.574744704745088 GO:0000340 RNA 7-methylguanosine cap binding 1/361 12/18639 0.0833333333333333 4.30263157894737 0.209244191851261 0.574744704745088 GO:0000995 RNA polymerase III general transcription initiation factor activity 1/361 12/18639 0.0833333333333333 4.30263157894737 0.209244191851261 0.574744704745088 GO:0004859 phospholipase inhibitor activity 1/361 12/18639 0.0833333333333333 4.30263157894737 0.209244191851261 0.574744704745088 GO:0005078 MAP-kinase scaffold activity 1/361 12/18639 0.0833333333333333 4.30263157894737 0.209244191851261 0.574744704745088 GO:0005095 GTPase inhibitor activity 1/361 12/18639 0.0833333333333333 4.30263157894737 0.209244191851261 0.574744704745088 GO:0010853 cyclase activator activity 1/361 12/18639 0.0833333333333333 4.30263157894737 0.209244191851261 0.574744704745088 GO:0031543 peptidyl-proline dioxygenase activity 1/361 12/18639 0.0833333333333333 4.30263157894737 0.209244191851261 0.574744704745088 GO:0035197 siRNA binding 1/361 12/18639 0.0833333333333333 4.30263157894737 0.209244191851261 0.574744704745088 GO:0035251 UDP-glucosyltransferase activity 1/361 12/18639 0.0833333333333333 4.30263157894737 0.209244191851261 0.574744704745088 GO:0035259 nuclear glucocorticoid receptor binding 1/361 12/18639 0.0833333333333333 4.30263157894737 0.209244191851261 0.574744704745088 GO:0043047 single-stranded telomeric DNA binding 1/361 12/18639 0.0833333333333333 4.30263157894737 0.209244191851261 0.574744704745088 GO:0045295 gamma-catenin binding 1/361 12/18639 0.0833333333333333 4.30263157894737 0.209244191851261 0.574744704745088 GO:0070410 co-SMAD binding 1/361 12/18639 0.0833333333333333 4.30263157894737 0.209244191851261 0.574744704745088 GO:0070679 inositol 1,4,5 trisphosphate binding 1/361 12/18639 0.0833333333333333 4.30263157894737 0.209244191851261 0.574744704745088 GO:0001046 core promoter sequence-specific DNA binding 2/361 44/18639 0.0454545454545455 2.34688995215311 0.209464562128565 0.574744704745088 GO:0001223 transcription coactivator binding 2/361 44/18639 0.0454545454545455 2.34688995215311 0.209464562128565 0.574744704745088 GO:0016248 channel inhibitor activity 2/361 44/18639 0.0454545454545455 2.34688995215311 0.209464562128565 0.574744704745088 GO:0030020 extracellular matrix structural constituent conferring tensile strength 2/361 44/18639 0.0454545454545455 2.34688995215311 0.209464562128565 0.574744704745088 GO:0140104 molecular carrier activity 7/361 249/18639 0.0281124497991968 1.45149017121116 0.209595534249618 0.574744704745088 GO:0015631 tubulin binding 10/361 385/18639 0.025974025974026 1.34107997265892 0.215063213959039 0.574744704745088 GO:0046915 transition metal ion transmembrane transporter activity 2/361 45/18639 0.0444444444444444 2.29473684210526 0.216589666750492 0.574744704745088 GO:0141110 transporter inhibitor activity 2/361 45/18639 0.0444444444444444 2.29473684210526 0.216589666750492 0.574744704745088 GO:0004527 exonuclease activity 3/361 84/18639 0.0357142857142857 1.84398496240602 0.222422301841522 0.574744704745088 GO:0004860 protein kinase inhibitor activity 3/361 84/18639 0.0357142857142857 1.84398496240602 0.222422301841522 0.574744704745088 GO:0051117 ATPase binding 3/361 84/18639 0.0357142857142857 1.84398496240602 0.222422301841522 0.574744704745088 GO:0030276 clathrin binding 2/361 46/18639 0.0434782608695652 2.24485125858124 0.2237360124988 0.574744704745088 GO:0030291 protein serine/threonine kinase inhibitor activity 2/361 46/18639 0.0434782608695652 2.24485125858124 0.2237360124988 0.574744704745088 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 1/361 13/18639 0.0769230769230769 3.97165991902834 0.224569410444791 0.574744704745088 GO:0005338 nucleotide-sugar transmembrane transporter activity 1/361 13/18639 0.0769230769230769 3.97165991902834 0.224569410444791 0.574744704745088 GO:0008253 5'-nucleotidase activity 1/361 13/18639 0.0769230769230769 3.97165991902834 0.224569410444791 0.574744704745088 GO:0019855 calcium channel inhibitor activity 1/361 13/18639 0.0769230769230769 3.97165991902834 0.224569410444791 0.574744704745088 GO:0045159 myosin II binding 1/361 13/18639 0.0769230769230769 3.97165991902834 0.224569410444791 0.574744704745088 GO:0051011 microtubule minus-end binding 1/361 13/18639 0.0769230769230769 3.97165991902834 0.224569410444791 0.574744704745088 GO:0071837 HMG box domain binding 1/361 13/18639 0.0769230769230769 3.97165991902834 0.224569410444791 0.574744704745088 GO:0140410 monoatomic cation:bicarbonate symporter activity 1/361 13/18639 0.0769230769230769 3.97165991902834 0.224569410444791 0.574744704745088 GO:0030414 peptidase inhibitor activity 5/361 169/18639 0.029585798816568 1.52756150731859 0.23061480785599 0.574744704745088 GO:0019783 ubiquitin-like protein peptidase activity 4/361 127/18639 0.031496062992126 1.62619146290924 0.232309269131892 0.574744704745088 GO:0042826 histone deacetylase binding 4/361 127/18639 0.031496062992126 1.62619146290924 0.232309269131892 0.574744704745088 GO:0016209 antioxidant activity 3/361 86/18639 0.0348837209302326 1.80110159118727 0.232648484521153 0.574744704745088 GO:0008081 phosphoric diester hydrolase activity 3/361 87/18639 0.0344827586206897 1.78039927404719 0.237793411552666 0.574744704745088 GO:0004705 JUN kinase activity 1/361 14/18639 0.0714285714285714 3.68796992481203 0.239598425951579 0.574744704745088 GO:0032036 myosin heavy chain binding 1/361 14/18639 0.0714285714285714 3.68796992481203 0.239598425951579 0.574744704745088 GO:0034236 protein kinase A catalytic subunit binding 1/361 14/18639 0.0714285714285714 3.68796992481203 0.239598425951579 0.574744704745088 GO:0070742 C2H2 zinc finger domain binding 1/361 14/18639 0.0714285714285714 3.68796992481203 0.239598425951579 0.574744704745088 GO:0098847 sequence-specific single stranded DNA binding 1/361 14/18639 0.0714285714285714 3.68796992481203 0.239598425951579 0.574744704745088 GO:1901612 cardiolipin binding 1/361 14/18639 0.0714285714285714 3.68796992481203 0.239598425951579 0.574744704745088 GO:0001222 transcription corepressor binding 2/361 49/18639 0.0408163265306122 2.10741138560687 0.245268285860753 0.574744704745088 GO:0005004 GPI-linked ephrin receptor activity 2/361 49/18639 0.0408163265306122 2.10741138560687 0.245268285860753 0.574744704745088 GO:0005008 hepatocyte growth factor receptor activity 2/361 49/18639 0.0408163265306122 2.10741138560687 0.245268285860753 0.574744704745088 GO:0005009 insulin receptor activity 2/361 49/18639 0.0408163265306122 2.10741138560687 0.245268285860753 0.574744704745088 GO:0005011 macrophage colony-stimulating factor receptor activity 2/361 49/18639 0.0408163265306122 2.10741138560687 0.245268285860753 0.574744704745088 GO:0005018 platelet-derived growth factor alpha-receptor activity 2/361 49/18639 0.0408163265306122 2.10741138560687 0.245268285860753 0.574744704745088 GO:0005020 stem cell factor receptor activity 2/361 49/18639 0.0408163265306122 2.10741138560687 0.245268285860753 0.574744704745088 GO:0008288 boss receptor activity 2/361 49/18639 0.0408163265306122 2.10741138560687 0.245268285860753 0.574744704745088 GO:0036332 placental growth factor receptor activity 2/361 49/18639 0.0408163265306122 2.10741138560687 0.245268285860753 0.574744704745088 GO:0038062 protein tyrosine kinase collagen receptor activity 2/361 49/18639 0.0408163265306122 2.10741138560687 0.245268285860753 0.574744704745088 GO:0060175 brain-derived neurotrophic factor receptor activity 2/361 49/18639 0.0408163265306122 2.10741138560687 0.245268285860753 0.574744704745088 GO:0060590 ATPase regulator activity 2/361 49/18639 0.0408163265306122 2.10741138560687 0.245268285860753 0.574744704745088 GO:0005006 epidermal growth factor receptor activity 2/361 50/18639 0.04 2.06526315789474 0.252466002666227 0.574744704745088 GO:0005007 fibroblast growth factor receptor activity 2/361 50/18639 0.04 2.06526315789474 0.252466002666227 0.574744704745088 GO:0005017 platelet-derived growth factor receptor activity 2/361 50/18639 0.04 2.06526315789474 0.252466002666227 0.574744704745088 GO:0005019 platelet-derived growth factor beta-receptor activity 2/361 50/18639 0.04 2.06526315789474 0.252466002666227 0.574744704745088 GO:0015605 organophosphate ester transmembrane transporter activity 2/361 50/18639 0.04 2.06526315789474 0.252466002666227 0.574744704745088 GO:0019210 kinase inhibitor activity 3/361 90/18639 0.0333333333333333 1.72105263157895 0.2533395718556 0.574744704745088 GO:0000774 adenyl-nucleotide exchange factor activity 1/361 15/18639 0.0666666666666667 3.44210526315789 0.25433694773582 0.574744704745088 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 1/361 15/18639 0.0666666666666667 3.44210526315789 0.25433694773582 0.574744704745088 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 1/361 15/18639 0.0666666666666667 3.44210526315789 0.25433694773582 0.574744704745088 GO:0004865 protein serine/threonine phosphatase inhibitor activity 1/361 15/18639 0.0666666666666667 3.44210526315789 0.25433694773582 0.574744704745088 GO:0004953 icosanoid receptor activity 1/361 15/18639 0.0666666666666667 3.44210526315789 0.25433694773582 0.574744704745088 GO:0005041 low-density lipoprotein particle receptor activity 1/361 15/18639 0.0666666666666667 3.44210526315789 0.25433694773582 0.574744704745088 GO:0005402 carbohydrate:monoatomic cation symporter activity 1/361 15/18639 0.0666666666666667 3.44210526315789 0.25433694773582 0.574744704745088 GO:0008242 omega peptidase activity 1/361 15/18639 0.0666666666666667 3.44210526315789 0.25433694773582 0.574744704745088 GO:0008252 nucleotidase activity 1/361 15/18639 0.0666666666666667 3.44210526315789 0.25433694773582 0.574744704745088 GO:0016846 carbon-sulfur lyase activity 1/361 15/18639 0.0666666666666667 3.44210526315789 0.25433694773582 0.574744704745088 GO:0017081 chloride channel regulator activity 1/361 15/18639 0.0666666666666667 3.44210526315789 0.25433694773582 0.574744704745088 GO:0034483 heparan sulfate sulfotransferase activity 1/361 15/18639 0.0666666666666667 3.44210526315789 0.25433694773582 0.574744704745088 GO:0050780 dopamine receptor binding 1/361 15/18639 0.0666666666666667 3.44210526315789 0.25433694773582 0.574744704745088 GO:0055105 ubiquitin-protein transferase inhibitor activity 1/361 15/18639 0.0666666666666667 3.44210526315789 0.25433694773582 0.574744704745088 GO:0061578 K63-linked deubiquitinase activity 1/361 15/18639 0.0666666666666667 3.44210526315789 0.25433694773582 0.574744704745088 GO:0072341 modified amino acid binding 3/361 91/18639 0.032967032967033 1.70213996529786 0.258554416966345 0.574744704745088 GO:0005010 insulin-like growth factor receptor activity 2/361 51/18639 0.0392156862745098 2.02476780185758 0.259668768915073 0.574744704745088 GO:0005021 vascular endothelial growth factor receptor activity 2/361 51/18639 0.0392156862745098 2.02476780185758 0.259668768915073 0.574744704745088 GO:0005030 neurotrophin receptor activity 2/361 51/18639 0.0392156862745098 2.02476780185758 0.259668768915073 0.574744704745088 GO:0030544 Hsp70 protein binding 2/361 51/18639 0.0392156862745098 2.02476780185758 0.259668768915073 0.574744704745088 GO:0016757 glycosyltransferase activity 7/361 267/18639 0.0262172284644195 1.35363690124187 0.26109372235562 0.574744704745088 GO:0051087 protein-folding chaperone binding 4/361 134/18639 0.0298507462686567 1.54124116260801 0.26176912278061 0.574744704745088 GO:0043178 alcohol binding 3/361 92/18639 0.0326086956521739 1.68363844393593 0.26378353459335 0.574744704745088 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 7/361 268/18639 0.0261194029850746 1.34858601728201 0.26405875579341 0.574744704745088 GO:0000062 fatty-acyl-CoA binding 1/361 16/18639 0.0625 3.22697368421053 0.268790575413406 0.574744704745088 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 1/361 16/18639 0.0625 3.22697368421053 0.268790575413406 0.574744704745088 GO:0004707 MAP kinase activity 1/361 16/18639 0.0625 3.22697368421053 0.268790575413406 0.574744704745088 GO:0005024 transforming growth factor beta receptor activity 1/361 16/18639 0.0625 3.22697368421053 0.268790575413406 0.574744704745088 GO:0008296 3'-5'-DNA exonuclease activity 1/361 16/18639 0.0625 3.22697368421053 0.268790575413406 0.574744704745088 GO:0017070 U6 snRNA binding 1/361 16/18639 0.0625 3.22697368421053 0.268790575413406 0.574744704745088 GO:0022858 alanine transmembrane transporter activity 1/361 16/18639 0.0625 3.22697368421053 0.268790575413406 0.574744704745088 GO:0031435 mitogen-activated protein kinase kinase kinase binding 1/361 16/18639 0.0625 3.22697368421053 0.268790575413406 0.574744704745088 GO:0034450 ubiquitin-ubiquitin ligase activity 1/361 16/18639 0.0625 3.22697368421053 0.268790575413406 0.574744704745088 GO:0055102 lipase inhibitor activity 1/361 16/18639 0.0625 3.22697368421053 0.268790575413406 0.574744704745088 GO:0061809 NAD+ nucleosidase activity, cyclic ADP-ribose generating 1/361 16/18639 0.0625 3.22697368421053 0.268790575413406 0.574744704745088 GO:0005003 ephrin receptor activity 2/361 53/18639 0.0377358490566038 1.94836146971202 0.274078010210592 0.574744704745088 GO:0005005 transmembrane-ephrin receptor activity 2/361 53/18639 0.0377358490566038 1.94836146971202 0.274078010210592 0.574744704745088 GO:0005544 calcium-dependent phospholipid binding 2/361 53/18639 0.0377358490566038 1.94836146971202 0.274078010210592 0.574744704745088 GO:0038064 collagen receptor activity 2/361 53/18639 0.0377358490566038 1.94836146971202 0.274078010210592 0.574744704745088 GO:0140463 chromatin-protein adaptor activity 2/361 54/18639 0.037037037037037 1.91228070175439 0.281279035713213 0.574744704745088 GO:0005092 GDP-dissociation inhibitor activity 1/361 17/18639 0.0588235294117647 3.03715170278638 0.282964800955787 0.574744704745088 GO:0008429 phosphatidylethanolamine binding 1/361 17/18639 0.0588235294117647 3.03715170278638 0.282964800955787 0.574744704745088 GO:0016018 cyclosporin A binding 1/361 17/18639 0.0588235294117647 3.03715170278638 0.282964800955787 0.574744704745088 GO:0030169 low-density lipoprotein particle binding 1/361 17/18639 0.0588235294117647 3.03715170278638 0.282964800955787 0.574744704745088 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 1/361 17/18639 0.0588235294117647 3.03715170278638 0.282964800955787 0.574744704745088 GO:0031489 myosin V binding 1/361 17/18639 0.0588235294117647 3.03715170278638 0.282964800955787 0.574744704745088 GO:0032183 SUMO binding 1/361 17/18639 0.0588235294117647 3.03715170278638 0.282964800955787 0.574744704745088 GO:0038191 neuropilin binding 1/361 17/18639 0.0588235294117647 3.03715170278638 0.282964800955787 0.574744704745088 GO:0046965 nuclear retinoid X receptor binding 1/361 17/18639 0.0588235294117647 3.03715170278638 0.282964800955787 0.574744704745088 GO:0048038 quinone binding 1/361 17/18639 0.0588235294117647 3.03715170278638 0.282964800955787 0.574744704745088 GO:0070403 NAD+ binding 1/361 17/18639 0.0588235294117647 3.03715170278638 0.282964800955787 0.574744704745088 GO:1901567 fatty acid derivative binding 1/361 17/18639 0.0588235294117647 3.03715170278638 0.282964800955787 0.574744704745088 GO:0004896 cytokine receptor activity 3/361 96/18639 0.03125 1.61348684210526 0.284818068565637 0.576054876564493 GO:0008237 metallopeptidase activity 5/361 184/18639 0.0271739130434783 1.40303203661327 0.28537687903425 0.576054876564493 GO:0140313 molecular sequestering activity 2/361 55/18639 0.0363636363636364 1.87751196172249 0.288474205386242 0.578410599833867 GO:0001217 DNA-binding transcription repressor activity 7/361 278/18639 0.0251798561151079 1.30007572889057 0.294191736630477 0.578410599833867 GO:0000400 four-way junction DNA binding 1/361 18/18639 0.0555555555555556 2.86842105263158 0.296865010753605 0.578410599833867 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 1/361 18/18639 0.0555555555555556 2.86842105263158 0.296865010753605 0.578410599833867 GO:0030228 lipoprotein particle receptor activity 1/361 18/18639 0.0555555555555556 2.86842105263158 0.296865010753605 0.578410599833867 GO:0031690 adrenergic receptor binding 1/361 18/18639 0.0555555555555556 2.86842105263158 0.296865010753605 0.578410599833867 GO:0035615 clathrin adaptor activity 1/361 18/18639 0.0555555555555556 2.86842105263158 0.296865010753605 0.578410599833867 GO:0050811 GABA receptor binding 1/361 18/18639 0.0555555555555556 2.86842105263158 0.296865010753605 0.578410599833867 GO:0070064 proline-rich region binding 1/361 18/18639 0.0555555555555556 2.86842105263158 0.296865010753605 0.578410599833867 GO:1901611 phosphatidylglycerol binding 1/361 18/18639 0.0555555555555556 2.86842105263158 0.296865010753605 0.578410599833867 GO:0004601 peroxidase activity 2/361 57/18639 0.0350877192982456 1.81163434903047 0.302837201214375 0.578410599833867 GO:0015932 nucleobase-containing compound transmembrane transporter activity 2/361 57/18639 0.0350877192982456 1.81163434903047 0.302837201214375 0.578410599833867 GO:0016504 peptidase activator activity 2/361 57/18639 0.0350877192982456 1.81163434903047 0.302837201214375 0.578410599833867 GO:0019903 protein phosphatase binding 4/361 144/18639 0.0277777777777778 1.43421052631579 0.304943655794241 0.578410599833867 GO:0008194 UDP-glycosyltransferase activity 4/361 145/18639 0.0275862068965517 1.42431941923775 0.309309360969623 0.578410599833867 GO:0008408 3'-5' exonuclease activity 2/361 58/18639 0.0344827586206897 1.78039927404719 0.310000379739324 0.578410599833867 GO:0003756 protein disulfide isomerase activity 1/361 19/18639 0.0526315789473684 2.71745152354571 0.31049648764088 0.578410599833867 GO:0005346 purine ribonucleotide transmembrane transporter activity 1/361 19/18639 0.0526315789473684 2.71745152354571 0.31049648764088 0.578410599833867 GO:0008301 DNA binding, bending 1/361 19/18639 0.0526315789473684 2.71745152354571 0.31049648764088 0.578410599833867 GO:0008574 plus-end-directed microtubule motor activity 1/361 19/18639 0.0526315789473684 2.71745152354571 0.31049648764088 0.578410599833867 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 1/361 19/18639 0.0526315789473684 2.71745152354571 0.31049648764088 0.578410599833867 GO:0034987 immunoglobulin receptor binding 1/361 19/18639 0.0526315789473684 2.71745152354571 0.31049648764088 0.578410599833867 GO:0042800 histone H3K4 methyltransferase activity 1/361 19/18639 0.0526315789473684 2.71745152354571 0.31049648764088 0.578410599833867 GO:0043395 heparan sulfate proteoglycan binding 1/361 19/18639 0.0526315789473684 2.71745152354571 0.31049648764088 0.578410599833867 GO:0046527 glucosyltransferase activity 1/361 19/18639 0.0526315789473684 2.71745152354571 0.31049648764088 0.578410599833867 GO:0120227 acyl-CoA binding 1/361 19/18639 0.0526315789473684 2.71745152354571 0.31049648764088 0.578410599833867 GO:1990380 K48-linked deubiquitinase activity 1/361 19/18639 0.0526315789473684 2.71745152354571 0.31049648764088 0.578410599833867 GO:0015459 potassium channel regulator activity 2/361 59/18639 0.0338983050847458 1.75022301516503 0.317148401597848 0.58578118368781 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 2/361 59/18639 0.0338983050847458 1.75022301516503 0.317148401597848 0.58578118368781 GO:0070888 E-box binding 2/361 59/18639 0.0338983050847458 1.75022301516503 0.317148401597848 0.58578118368781 GO:0000339 RNA cap binding 1/361 20/18639 0.05 2.58157894736842 0.323864412880495 0.588941558359326 GO:0010851 cyclase regulator activity 1/361 20/18639 0.05 2.58157894736842 0.323864412880495 0.588941558359326 GO:0043024 ribosomal small subunit binding 1/361 20/18639 0.05 2.58157894736842 0.323864412880495 0.588941558359326 GO:0052745 inositol phosphate phosphatase activity 1/361 20/18639 0.05 2.58157894736842 0.323864412880495 0.588941558359326 GO:0004714 transmembrane receptor protein tyrosine kinase activity 2/361 60/18639 0.0333333333333333 1.72105263157895 0.324279170937113 0.588941558359326 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 2/361 60/18639 0.0333333333333333 1.72105263157895 0.324279170937113 0.588941558359326 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 1/361 21/18639 0.0476190476190476 2.45864661654135 0.336973868111718 0.605253338867329 GO:0009931 calcium-dependent protein serine/threonine kinase activity 1/361 21/18639 0.0476190476190476 2.45864661654135 0.336973868111718 0.605253338867329 GO:0051428 peptide hormone receptor binding 1/361 21/18639 0.0476190476190476 2.45864661654135 0.336973868111718 0.605253338867329 GO:0140312 cargo adaptor activity 1/361 21/18639 0.0476190476190476 2.45864661654135 0.336973868111718 0.605253338867329 GO:0003774 cytoskeletal motor activity 4/361 153/18639 0.0261437908496732 1.34984520123839 0.344405395594684 0.61690197232894 GO:0030021 extracellular matrix structural constituent conferring compression resistance 1/361 22/18639 0.0454545454545455 2.34688995215311 0.349829837260481 0.623194136321951 GO:0061133 endopeptidase activator activity 1/361 22/18639 0.0454545454545455 2.34688995215311 0.349829837260481 0.623194136321951 GO:0042277 peptide binding 6/361 249/18639 0.0240963855421687 1.24413443246671 0.352402237684494 0.6246988775682 GO:0004536 DNA nuclease activity 2/361 64/18639 0.03125 1.61348684210526 0.352590777523156 0.6246988775682 GO:0004620 phospholipase activity 3/361 109/18639 0.0275229357798165 1.42105263157895 0.353727237240697 0.625013980165135 GO:0000295 adenine nucleotide transmembrane transporter activity 1/361 23/18639 0.0434782608695652 2.24485125858124 0.362437208413136 0.627250709343219 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 1/361 23/18639 0.0434782608695652 2.24485125858124 0.362437208413136 0.627250709343219 GO:0005158 insulin receptor binding 1/361 23/18639 0.0434782608695652 2.24485125858124 0.362437208413136 0.627250709343219 GO:0005283 amino acid:sodium symporter activity 1/361 23/18639 0.0434782608695652 2.24485125858124 0.362437208413136 0.627250709343219 GO:0070577 lysine-acetylated histone binding 1/361 23/18639 0.0434782608695652 2.24485125858124 0.362437208413136 0.627250709343219 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 1/361 23/18639 0.0434782608695652 2.24485125858124 0.362437208413136 0.627250709343219 GO:0031625 ubiquitin protein ligase binding 7/361 302/18639 0.0231788079470199 1.19675845242245 0.369007661313131 0.627250709343219 GO:0019887 protein kinase regulator activity 6/361 255/18639 0.0235294117647059 1.21486068111455 0.373096360544657 0.627250709343219 GO:0016500 protein-hormone receptor activity 2/361 67/18639 0.0298507462686567 1.54124116260801 0.373552953192856 0.627250709343219 GO:0005540 hyaluronic acid binding 1/361 24/18639 0.0416666666666667 2.15131578947368 0.374800775654372 0.627250709343219 GO:0015149 hexose transmembrane transporter activity 1/361 24/18639 0.0416666666666667 2.15131578947368 0.374800775654372 0.627250709343219 GO:0015295 solute:proton symporter activity 1/361 24/18639 0.0416666666666667 2.15131578947368 0.374800775654372 0.627250709343219 GO:0042625 ATPase-coupled ion transmembrane transporter activity 1/361 24/18639 0.0416666666666667 2.15131578947368 0.374800775654372 0.627250709343219 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 1/361 24/18639 0.0416666666666667 2.15131578947368 0.374800775654372 0.627250709343219 GO:0046961 proton-transporting ATPase activity, rotational mechanism 1/361 24/18639 0.0416666666666667 2.15131578947368 0.374800775654372 0.627250709343219 GO:0050431 transforming growth factor beta binding 1/361 24/18639 0.0416666666666667 2.15131578947368 0.374800775654372 0.627250709343219 GO:0050699 WW domain binding 1/361 24/18639 0.0416666666666667 2.15131578947368 0.374800775654372 0.627250709343219 GO:0055056 D-glucose transmembrane transporter activity 1/361 24/18639 0.0416666666666667 2.15131578947368 0.374800775654372 0.627250709343219 GO:0070840 dynein complex binding 1/361 24/18639 0.0416666666666667 2.15131578947368 0.374800775654372 0.627250709343219 GO:0140033 acetylation-dependent protein binding 1/361 24/18639 0.0416666666666667 2.15131578947368 0.374800775654372 0.627250709343219 GO:0099106 ion channel regulator activity 4/361 160/18639 0.025 1.29078947368421 0.375195976447631 0.627250709343219 GO:0140223 general transcription initiation factor activity 2/361 68/18639 0.0294117647058824 1.51857585139319 0.380480103049497 0.634457870046732 GO:0000030 mannosyltransferase activity 1/361 25/18639 0.04 2.06526315789474 0.386925240869992 0.639413485505334 GO:0016895 DNA exonuclease activity, producing 5'-phosphomonoesters 1/361 25/18639 0.04 2.06526315789474 0.386925240869992 0.639413485505334 GO:0002039 p53 binding 2/361 69/18639 0.0289855072463768 1.49656750572082 0.387374734316882 0.639413485505334 GO:0008080 N-acetyltransferase activity 2/361 69/18639 0.0289855072463768 1.49656750572082 0.387374734316882 0.639413485505334 GO:0015294 solute:monoatomic cation symporter activity 3/361 116/18639 0.0258620689655172 1.33529945553539 0.390606847680756 0.640461873191901 GO:0003730 mRNA 3'-UTR binding 6/361 262/18639 0.0229007633587786 1.18240257131378 0.397283339229772 0.640461873191901 GO:0004435 phosphatidylinositol phospholipase C activity 1/361 26/18639 0.0384615384615385 1.98582995951417 0.398815215515202 0.640461873191901 GO:0004529 DNA exonuclease activity 1/361 26/18639 0.0384615384615385 1.98582995951417 0.398815215515202 0.640461873191901 GO:0005112 Notch binding 1/361 26/18639 0.0384615384615385 1.98582995951417 0.398815215515202 0.640461873191901 GO:0015145 monosaccharide transmembrane transporter activity 1/361 26/18639 0.0384615384615385 1.98582995951417 0.398815215515202 0.640461873191901 GO:0015216 purine nucleotide transmembrane transporter activity 1/361 26/18639 0.0384615384615385 1.98582995951417 0.398815215515202 0.640461873191901 GO:0019865 immunoglobulin binding 1/361 26/18639 0.0384615384615385 1.98582995951417 0.398815215515202 0.640461873191901 GO:0030507 spectrin binding 1/361 26/18639 0.0384615384615385 1.98582995951417 0.398815215515202 0.640461873191901 GO:0050681 nuclear androgen receptor binding 1/361 26/18639 0.0384615384615385 1.98582995951417 0.398815215515202 0.640461873191901 GO:0070006 metalloaminopeptidase activity 1/361 26/18639 0.0384615384615385 1.98582995951417 0.398815215515202 0.640461873191901 GO:0016247 channel regulator activity 4/361 168/18639 0.0238095238095238 1.22932330827068 0.410223781969367 0.644891192702655 GO:0001671 ATPase activator activity 1/361 27/18639 0.037037037037037 1.91228070175439 0.410475222349083 0.644891192702655 GO:0005044 scavenger receptor activity 1/361 27/18639 0.037037037037037 1.91228070175439 0.410475222349083 0.644891192702655 GO:0005385 zinc ion transmembrane transporter activity 1/361 27/18639 0.037037037037037 1.91228070175439 0.410475222349083 0.644891192702655 GO:0008266 poly(U) RNA binding 1/361 27/18639 0.037037037037037 1.91228070175439 0.410475222349083 0.644891192702655 GO:0008395 steroid hydroxylase activity 1/361 27/18639 0.037037037037037 1.91228070175439 0.410475222349083 0.644891192702655 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors 1/361 27/18639 0.037037037037037 1.91228070175439 0.410475222349083 0.644891192702655 GO:0023026 MHC class II protein complex binding 1/361 27/18639 0.037037037037037 1.91228070175439 0.410475222349083 0.644891192702655 GO:0035255 ionotropic glutamate receptor binding 1/361 27/18639 0.037037037037037 1.91228070175439 0.410475222349083 0.644891192702655 GO:0141108 transporter regulator activity 4/361 170/18639 0.0235294117647059 1.21486068111455 0.418925104549782 0.654964577458565 GO:0050698 proteoglycan sulfotransferase activity 1/361 28/18639 0.0357142857142857 1.84398496240602 0.421909697135885 0.654964577458565 GO:0051119 sugar transmembrane transporter activity 1/361 28/18639 0.0357142857142857 1.84398496240602 0.421909697135885 0.654964577458565 GO:0051959 dynein light intermediate chain binding 1/361 28/18639 0.0357142857142857 1.84398496240602 0.421909697135885 0.654964577458565 GO:0097718 disordered domain specific binding 1/361 28/18639 0.0357142857142857 1.84398496240602 0.421909697135885 0.654964577458565 GO:0044389 ubiquitin-like protein ligase binding 7/361 322/18639 0.0217391304347826 1.12242562929062 0.43229546856725 0.667603285306359 GO:0005416 amino acid:monoatomic cation symporter activity 1/361 29/18639 0.0344827586206897 1.78039927404719 0.433122990313788 0.667603285306359 GO:0106222 lncRNA binding 1/361 29/18639 0.0344827586206897 1.78039927404719 0.433122990313788 0.667603285306359 GO:0008187 poly-pyrimidine tract binding 1/361 30/18639 0.0333333333333333 1.72105263157895 0.444119368631721 0.679731991426953 GO:0015215 nucleotide transmembrane transporter activity 1/361 30/18639 0.0333333333333333 1.72105263157895 0.444119368631721 0.679731991426953 GO:0031210 phosphatidylcholine binding 1/361 30/18639 0.0333333333333333 1.72105263157895 0.444119368631721 0.679731991426953 GO:0005164 tumor necrosis factor receptor binding 1/361 31/18639 0.032258064516129 1.66553480475382 0.454903016754884 0.691367755068029 GO:0008327 methyl-CpG binding 1/361 31/18639 0.032258064516129 1.66553480475382 0.454903016754884 0.691367755068029 GO:0017147 Wnt-protein binding 1/361 31/18639 0.032258064516129 1.66553480475382 0.454903016754884 0.691367755068029 GO:0000049 tRNA binding 2/361 80/18639 0.025 1.29078947368421 0.460729731510995 0.696081837897678 GO:0016298 lipase activity 3/361 130/18639 0.0230769230769231 1.1914979757085 0.462498198716655 0.696081837897678 GO:0016798 hydrolase activity, acting on glycosyl bonds 3/361 130/18639 0.0230769230769231 1.1914979757085 0.462498198716655 0.696081837897678 GO:0015106 bicarbonate transmembrane transporter activity 1/361 32/18639 0.03125 1.61348684210526 0.465478038839551 0.696081837897678 GO:0030515 snoRNA binding 1/361 32/18639 0.03125 1.61348684210526 0.465478038839551 0.696081837897678 GO:0071813 lipoprotein particle binding 1/361 32/18639 0.03125 1.61348684210526 0.465478038839551 0.696081837897678 GO:0071814 protein-lipid complex binding 1/361 32/18639 0.03125 1.61348684210526 0.465478038839551 0.696081837897678 GO:0031072 heat shock protein binding 3/361 131/18639 0.0229007633587786 1.18240257131378 0.467500921902825 0.697507096294375 GO:0019956 chemokine binding 1/361 33/18639 0.0303030303030303 1.56459330143541 0.475848460077737 0.706727097883108 GO:0030296 protein tyrosine kinase activator activity 1/361 33/18639 0.0303030303030303 1.56459330143541 0.475848460077737 0.706727097883108 GO:0019207 kinase regulator activity 6/361 287/18639 0.0209059233449477 1.0794058316523 0.482750409050916 0.715348333411811 GO:0016831 carboxy-lyase activity 1/361 34/18639 0.0294117647058824 1.51857585139319 0.486018228212314 0.718557561892128 GO:0002020 protease binding 3/361 136/18639 0.0220588235294118 1.13893188854489 0.492194136501777 0.723459221912942 GO:0044325 transmembrane transporter binding 3/361 136/18639 0.0220588235294118 1.13893188854489 0.492194136501777 0.723459221912942 GO:0000175 3'-5'-RNA exonuclease activity 1/361 35/18639 0.0285714285714286 1.47518796992481 0.495991215023136 0.723459221912942 GO:0005154 epidermal growth factor receptor binding 1/361 35/18639 0.0285714285714286 1.47518796992481 0.495991215023136 0.723459221912942 GO:0005343 organic acid:sodium symporter activity 1/361 35/18639 0.0285714285714286 1.47518796992481 0.495991215023136 0.723459221912942 GO:0061631 ubiquitin conjugating enzyme activity 1/361 35/18639 0.0285714285714286 1.47518796992481 0.495991215023136 0.723459221912942 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 2/361 86/18639 0.0232558139534884 1.20073439412485 0.498536593756964 0.723932871112562 GO:0050660 flavin adenine dinucleotide binding 2/361 86/18639 0.0232558139534884 1.20073439412485 0.498536593756964 0.723932871112562 GO:0019902 phosphatase binding 4/361 190/18639 0.0210526315789474 1.08698060941828 0.503756906018777 0.72613752207525 GO:0000993 RNA polymerase II complex binding 1/361 36/18639 0.0277777777777778 1.43421052631579 0.505771217784728 0.72613752207525 GO:0004190 aspartic-type endopeptidase activity 1/361 36/18639 0.0277777777777778 1.43421052631579 0.505771217784728 0.72613752207525 GO:0045505 dynein intermediate chain binding 1/361 36/18639 0.0277777777777778 1.43421052631579 0.505771217784728 0.72613752207525 GO:0055106 ubiquitin-protein transferase regulator activity 1/361 36/18639 0.0277777777777778 1.43421052631579 0.505771217784728 0.72613752207525 GO:0030295 protein kinase activator activity 3/361 139/18639 0.0215827338129496 1.11435062476335 0.506737074454354 0.72613752207525 GO:0023023 MHC protein complex binding 1/361 37/18639 0.027027027027027 1.39544807965861 0.515361960696071 0.735264766682359 GO:0070001 aspartic-type peptidase activity 1/361 37/18639 0.027027027027027 1.39544807965861 0.515361960696071 0.735264766682359 GO:0005109 frizzled binding 1/361 38/18639 0.0263157894736842 1.35872576177285 0.524767096283036 0.743800319079433 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 1/361 38/18639 0.0263157894736842 1.35872576177285 0.524767096283036 0.743800319079433 GO:0043531 ADP binding 1/361 38/18639 0.0263157894736842 1.35872576177285 0.524767096283036 0.743800319079433 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 2/361 91/18639 0.021978021978022 1.13475997686524 0.528720639099177 0.747778431003608 GO:0000217 DNA secondary structure binding 1/361 39/18639 0.0256410256410256 1.32388663967611 0.533990206773967 0.748538463324974 GO:0015293 symporter activity 3/361 146/18639 0.0205479452054795 1.06092285508291 0.539803839837036 0.748538463324974 GO:0051213 dioxygenase activity 2/361 93/18639 0.021505376344086 1.11035653650255 0.540445107288895 0.748538463324974 GO:0051219 phosphoprotein binding 2/361 93/18639 0.021505376344086 1.11035653650255 0.540445107288895 0.748538463324974 GO:0004177 aminopeptidase activity 1/361 40/18639 0.025 1.29078947368421 0.543034805448946 0.748538463324974 GO:0004532 RNA exonuclease activity 1/361 40/18639 0.025 1.29078947368421 0.543034805448946 0.748538463324974 GO:0030331 nuclear estrogen receptor binding 1/361 40/18639 0.025 1.29078947368421 0.543034805448946 0.748538463324974 GO:0050997 quaternary ammonium group binding 1/361 40/18639 0.025 1.29078947368421 0.543034805448946 0.748538463324974 GO:0061791 GTPase motor activity 1/361 40/18639 0.025 1.29078947368421 0.543034805448946 0.748538463324974 GO:0071855 neuropeptide receptor binding 1/361 40/18639 0.025 1.29078947368421 0.543034805448946 0.748538463324974 GO:0140662 ATP-dependent protein folding chaperone 1/361 40/18639 0.025 1.29078947368421 0.543034805448946 0.748538463324974 GO:1990606 membrane scission GTPase motor activity 1/361 40/18639 0.025 1.29078947368421 0.543034805448946 0.748538463324974 GO:0016410 N-acyltransferase activity 2/361 94/18639 0.0212765957446809 1.09854423292273 0.546231313577726 0.751235132258909 GO:0019209 kinase activator activity 3/361 148/18639 0.0202702702702703 1.04658605974395 0.549016271861555 0.751235132258909 GO:0015175 neutral L-amino acid transmembrane transporter activity 1/361 41/18639 0.024390243902439 1.25930680359435 0.551904337963217 0.751235132258909 GO:0017080 sodium channel regulator activity 1/361 41/18639 0.024390243902439 1.25930680359435 0.551904337963217 0.751235132258909 GO:0042169 SH2 domain binding 1/361 41/18639 0.024390243902439 1.25930680359435 0.551904337963217 0.751235132258909 GO:0061650 ubiquitin-like protein conjugating enzyme activity 1/361 41/18639 0.024390243902439 1.25930680359435 0.551904337963217 0.751235132258909 GO:0016407 acetyltransferase activity 2/361 96/18639 0.0208333333333333 1.07565789473684 0.557650531134549 0.753634275745839 GO:0004520 DNA endonuclease activity 1/361 42/18639 0.0238095238095238 1.22932330827068 0.560602183645295 0.753634275745839 GO:0042056 chemoattractant activity 1/361 42/18639 0.0238095238095238 1.22932330827068 0.560602183645295 0.753634275745839 GO:0043175 RNA polymerase core enzyme binding 1/361 42/18639 0.0238095238095238 1.22932330827068 0.560602183645295 0.753634275745839 GO:0048487 beta-tubulin binding 1/361 42/18639 0.0238095238095238 1.22932330827068 0.560602183645295 0.753634275745839 GO:0051879 Hsp90 protein binding 1/361 42/18639 0.0238095238095238 1.22932330827068 0.560602183645295 0.753634275745839 GO:0042626 ATPase-coupled transmembrane transporter activity 2/361 98/18639 0.0204081632653061 1.05370569280344 0.568864288847354 0.761958604135887 GO:0048156 tau protein binding 1/361 43/18639 0.0232558139534884 1.20073439412485 0.56913165677021 0.761958604135887 GO:0005506 iron ion binding 3/361 154/18639 0.0194805194805195 1.00580997949419 0.575992338888709 0.769563534744751 GO:0019205 nucleobase-containing compound kinase activity 1/361 44/18639 0.0227272727272727 1.17344497607656 0.577496007808388 0.76999467707785 GO:0140375 immune receptor activity 3/361 156/18639 0.0192307692307692 0.992914979757085 0.584757794906699 0.777750250248879 GO:0042605 peptide antigen binding 1/361 45/18639 0.0222222222222222 1.14736842105263 0.585698424650613 0.777750250248879 GO:0008238 exopeptidase activity 2/361 102/18639 0.0196078431372549 1.01238390092879 0.590671485810636 0.782759773879135 GO:0008514 organic anion transmembrane transporter activity 5/361 269/18639 0.0185873605947955 0.959694775973391 0.599000959149464 0.792187881065823 GO:0005525 GTP binding 7/361 378/18639 0.0185185185185185 0.956140350877193 0.600694864688789 0.792449890589969 GO:0140938 histone H3 methyltransferase activity 1/361 47/18639 0.0212765957446809 1.09854423292273 0.601629901598213 0.792449890589969 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 1/361 48/18639 0.0208333333333333 1.07565789473684 0.609365035285984 0.799408456753444 GO:0032266 phosphatidylinositol-3-phosphate binding 1/361 48/18639 0.0208333333333333 1.07565789473684 0.609365035285984 0.799408456753444 GO:0008013 beta-catenin binding 2/361 106/18639 0.0188679245283019 0.974180734856008 0.611648702203074 0.80079307999278 GO:0016763 pentosyltransferase activity 1/361 49/18639 0.0204081632653061 1.05370569280344 0.616950384232343 0.804503301038975 GO:0035254 glutamate receptor binding 1/361 49/18639 0.0204081632653061 1.05370569280344 0.616950384232343 0.804503301038975 GO:0032813 tumor necrosis factor receptor superfamily binding 1/361 50/18639 0.02 1.03263157894737 0.624388840998998 0.81257789287694 GO:0016830 carbon-carbon lyase activity 1/361 51/18639 0.0196078431372549 1.01238390092879 0.631683242440677 0.820433215281517 GO:1902936 phosphatidylinositol bisphosphate binding 2/361 111/18639 0.018018018018018 0.930298719772404 0.636705166883919 0.825311667610964 GO:0031267 small GTPase binding 5/361 283/18639 0.0176678445229682 0.912218709317463 0.643574031647332 0.827076183467341 GO:0005246 calcium channel regulator activity 1/361 53/18639 0.0188679245283019 0.974180734856008 0.645850954632036 0.827076183467341 GO:0008146 sulfotransferase activity 1/361 53/18639 0.0188679245283019 0.974180734856008 0.645850954632036 0.827076183467341 GO:0016860 intramolecular oxidoreductase activity 1/361 53/18639 0.0188679245283019 0.974180734856008 0.645850954632036 0.827076183467341 GO:0140296 general transcription initiation factor binding 1/361 53/18639 0.0188679245283019 0.974180734856008 0.645850954632036 0.827076183467341 GO:0035091 phosphatidylinositol binding 5/361 284/18639 0.0176056338028169 0.909006671608599 0.646637270943773 0.827076183467341 GO:0003925 G protein activity 1/361 54/18639 0.0185185185185185 0.956140350877193 0.652729670083335 0.827076183467341 GO:0015485 cholesterol binding 1/361 54/18639 0.0185185185185185 0.956140350877193 0.652729670083335 0.827076183467341 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 1/361 54/18639 0.0185185185185185 0.956140350877193 0.652729670083335 0.827076183467341 GO:0051287 NAD binding 1/361 54/18639 0.0185185185185185 0.956140350877193 0.652729670083335 0.827076183467341 GO:0000287 magnesium ion binding 4/361 230/18639 0.0173913043478261 0.897940503432494 0.653969698891962 0.827076183467341 GO:0005085 guanyl-nucleotide exchange factor activity 4/361 230/18639 0.0173913043478261 0.897940503432494 0.653969698891962 0.827076183467341 GO:0035401 histone H3Y41 kinase activity 2/361 115/18639 0.0173913043478261 0.897940503432494 0.655825746706465 0.827076183467341 GO:0140801 histone H2AXY142 kinase activity 2/361 115/18639 0.0173913043478261 0.897940503432494 0.655825746706465 0.827076183467341 GO:0019001 guanyl nucleotide binding 7/361 400/18639 0.0175 0.903552631578947 0.659457732694782 0.828451718144505 GO:0032561 guanyl ribonucleotide binding 7/361 400/18639 0.0175 0.903552631578947 0.659457732694782 0.828451718144505 GO:0032182 ubiquitin-like protein binding 2/361 120/18639 0.0166666666666667 0.860526315789474 0.678587625390647 0.849304782013096 GO:0016853 isomerase activity 3/361 180/18639 0.0166666666666667 0.860526315789474 0.680637934004978 0.849304782013096 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 3/361 181/18639 0.0165745856353591 0.855772026751963 0.684252763949027 0.849304782013096 GO:0004879 nuclear receptor activity 1/361 59/18639 0.0169491525423729 0.875111507582516 0.685175330274369 0.849304782013096 GO:0031593 polyubiquitin modification-dependent protein binding 1/361 59/18639 0.0169491525423729 0.875111507582516 0.685175330274369 0.849304782013096 GO:0045309 protein phosphorylated amino acid binding 1/361 59/18639 0.0169491525423729 0.875111507582516 0.685175330274369 0.849304782013096 GO:0070063 RNA polymerase binding 1/361 59/18639 0.0169491525423729 0.875111507582516 0.685175330274369 0.849304782013096 GO:0001098 basal transcription machinery binding 1/361 60/18639 0.0166666666666667 0.860526315789474 0.691292214330933 0.850419856120317 GO:0001099 basal RNA polymerase II transcription machinery binding 1/361 60/18639 0.0166666666666667 0.860526315789474 0.691292214330933 0.850419856120317 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 1/361 60/18639 0.0166666666666667 0.860526315789474 0.691292214330933 0.850419856120317 GO:0098531 ligand-modulated transcription factor activity 1/361 60/18639 0.0166666666666667 0.860526315789474 0.691292214330933 0.850419856120317 GO:0016836 hydro-lyase activity 1/361 61/18639 0.0163934426229508 0.84641932700604 0.697290573264488 0.855942922377545 GO:1901981 phosphatidylinositol phosphate binding 3/361 185/18639 0.0162162162162162 0.837268847795164 0.698407415191494 0.855942922377545 GO:0015179 L-amino acid transmembrane transporter activity 1/361 62/18639 0.0161290322580645 0.83276740237691 0.703172697446398 0.860166226519797 GO:0031406 carboxylic acid binding 3/361 187/18639 0.0160427807486631 0.828314100759921 0.705302576685993 0.861155955054808 GO:0046943 carboxylic acid transmembrane transporter activity 3/361 188/18639 0.0159574468085106 0.823908174692049 0.708704814311544 0.863404113322611 GO:0005342 organic acid transmembrane transporter activity 3/361 189/18639 0.0158730158730159 0.819548872180451 0.71207691258273 0.863404113322611 GO:0043177 organic acid binding 3/361 189/18639 0.0158730158730159 0.819548872180451 0.71207691258273 0.863404113322611 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 2/361 128/18639 0.015625 0.806743421052632 0.712440817434915 0.863404113322611 GO:0035591 signaling adaptor activity 2/361 129/18639 0.0155038759689922 0.800489596083231 0.71645602262839 0.866659233309296 GO:0038024 cargo receptor activity 1/361 65/18639 0.0153846153846154 0.794331983805668 0.720143908198109 0.869507089157717 GO:0008235 metalloexopeptidase activity 1/361 66/18639 0.0151515151515152 0.782296650717703 0.725583126952308 0.874455080911099 GO:0042054 histone methyltransferase activity 1/361 67/18639 0.0149253731343284 0.770620581304006 0.730916917463815 0.876045407389686 GO:0051020 GTPase binding 5/361 315/18639 0.0158730158730159 0.819548872180451 0.733189413836895 0.876045407389686 GO:0030695 GTPase regulator activity 8/361 489/18639 0.016359918200409 0.844688408136907 0.734265977531475 0.876045407389686 GO:0005548 phospholipid transporter activity 1/361 68/18639 0.0147058823529412 0.759287925696595 0.736147317678954 0.876045407389686 GO:0030145 manganese ion binding 1/361 68/18639 0.0147058823529412 0.759287925696595 0.736147317678954 0.876045407389686 GO:0032934 sterol binding 1/361 68/18639 0.0147058823529412 0.759287925696595 0.736147317678954 0.876045407389686 GO:0060589 nucleoside-triphosphatase regulator activity 8/361 490/18639 0.0163265306122449 0.84296455424275 0.736308103143478 0.876045407389686 GO:0016279 protein-lysine N-methyltransferase activity 1/361 69/18639 0.0144927536231884 0.748283752860412 0.741276326257808 0.880350026812551 GO:0016779 nucleotidyltransferase activity 2/361 136/18639 0.0147058823529412 0.759287925696595 0.743261160461917 0.880972276255994 GO:0016278 lysine N-methyltransferase activity 1/361 70/18639 0.0142857142857143 0.737593984962406 0.746305903329479 0.880972276255994 GO:0016782 transferase activity, transferring sulphur-containing groups 1/361 70/18639 0.0142857142857143 0.737593984962406 0.746305903329479 0.880972276255994 GO:0016829 lyase activity 3/361 200/18639 0.015 0.774473684210526 0.747205013450252 0.880972276255994 GO:0005543 phospholipid binding 8/361 497/18639 0.0160965794768612 0.831091814042148 0.750303144865301 0.883028249913676 GO:0070851 growth factor receptor binding 2/361 139/18639 0.0143884892086331 0.742900416508898 0.754070126280458 0.885862562765511 GO:0004713 protein tyrosine kinase activity 2/361 140/18639 0.0142857142857143 0.737593984962406 0.757585103870099 0.888391164969973 GO:0140098 catalytic activity, acting on RNA 6/361 387/18639 0.0155038759689922 0.800489596083231 0.7635904026491 0.892817531561606 GO:0020037 heme binding 2/361 142/18639 0.0140845070422535 0.727205337286879 0.764485167560443 0.892817531561606 GO:0003678 DNA helicase activity 1/361 74/18639 0.0135135135135135 0.697724039829303 0.765467791630273 0.892817531561606 GO:0005516 calmodulin binding 3/361 207/18639 0.0144927536231884 0.748283752860412 0.767725581644882 0.893342458650336 GO:0019003 GDP binding 1/361 75/18639 0.0133333333333333 0.688421052631579 0.770028315585105 0.893342458650336 GO:0044183 protein folding chaperone 1/361 75/18639 0.0133333333333333 0.688421052631579 0.770028315585105 0.893342458650336 GO:0004518 nuclease activity 3/361 209/18639 0.0143540669856459 0.741123142785193 0.77333408130866 0.895584051533297 GO:0015370 solute:sodium symporter activity 1/361 79/18639 0.0126582278481013 0.653564290473018 0.787402957090084 0.908649076146433 GO:0016835 carbon-oxygen lyase activity 1/361 79/18639 0.0126582278481013 0.653564290473018 0.787402957090084 0.908649076146433 GO:0019842 vitamin binding 2/361 150/18639 0.0133333333333333 0.688421052631579 0.790406704924384 0.910503836768018 GO:0001618 virus receptor activity 1/361 81/18639 0.0123456790123457 0.637426900584795 0.795592954249902 0.912664936987514 GO:0015101 organic cation transmembrane transporter activity 1/361 81/18639 0.0123456790123457 0.637426900584795 0.795592954249902 0.912664936987514 GO:0046906 tetrapyrrole binding 2/361 152/18639 0.0131578947368421 0.679362880886427 0.796482130591864 0.912664936987514 GO:0140272 exogenous protein binding 1/361 82/18639 0.0121951219512195 0.629653401797176 0.799569187869677 0.914594930686017 GO:0001540 amyloid-beta binding 1/361 83/18639 0.0120481927710843 0.622067216233354 0.803468283800003 0.9174453958627 GO:0015291 secondary active transmembrane transporter activity 4/361 287/18639 0.0139372822299652 0.719603887768201 0.809784387421181 0.923040945102465 GO:0015399 primary active transmembrane transporter activity 2/361 166/18639 0.0120481927710843 0.622067216233354 0.83480847400723 0.947186980596071 GO:0042578 phosphoric ester hydrolase activity 5/361 363/18639 0.0137741046831956 0.71117877337973 0.835102113092735 0.947186980596071 GO:0052689 carboxylic ester hydrolase activity 1/361 92/18639 0.0108695652173913 0.561212814645309 0.835325941476596 0.947186980596071 GO:0042562 hormone binding 1/361 94/18639 0.0106382978723404 0.549272116461366 0.841674177121797 0.952728408825367 GO:0008276 protein methyltransferase activity 1/361 95/18639 0.0105263157894737 0.543490304709141 0.844756173458224 0.954559835519518 GO:0008170 N-methyltransferase activity 1/361 98/18639 0.0102040816326531 0.526852846401719 0.853647783482398 0.962938330156615 GO:0004252 serine-type endopeptidase activity 2/361 176/18639 0.0113636363636364 0.586722488038278 0.858067360074978 0.965407477144251 GO:0043130 ubiquitin binding 1/361 100/18639 0.01 0.516315789473684 0.859291514344529 0.965407477144251 GO:0033218 amide binding 3/361 247/18639 0.0121457489878543 0.627104197741317 0.860278748804923 0.965407477144251 GO:0015171 amino acid transmembrane transporter activity 1/361 102/18639 0.00980392156862745 0.506191950464396 0.864718187559409 0.968722093279613 GO:0005253 monoatomic anion channel activity 1/361 103/18639 0.00970873786407767 0.501277465508431 0.867352741925868 0.970006840026871 GO:0004497 monooxygenase activity 1/361 106/18639 0.00943396226415094 0.487090367428004 0.874953345472749 0.976779067270538 GO:0015078 proton transmembrane transporter activity 2/361 185/18639 0.0108108108108108 0.558179231863442 0.876404531216664 0.976779067270538 GO:0005496 steroid binding 1/361 108/18639 0.00925925925925926 0.478070175438596 0.879777538293755 0.97795228987305 GO:0022804 active transmembrane transporter activity 6/361 457/18639 0.0131291028446389 0.677876310031095 0.880457046250737 0.97795228987305 GO:0003924 GTPase activity 4/361 331/18639 0.0120845921450151 0.623946573382096 0.886434119849488 0.980386097879288 GO:0008236 serine-type peptidase activity 2/361 194/18639 0.0103092783505155 0.532284319045035 0.892538816184514 0.980386097879288 GO:0017124 SH3 domain binding 1/361 115/18639 0.00869565217391304 0.448970251716247 0.895246550095951 0.980386097879288 GO:0005096 GTPase activator activity 3/361 271/18639 0.011070110701107 0.571567294620315 0.898774841379831 0.980386097879288 GO:0017171 serine hydrolase activity 2/361 198/18639 0.0101010101010101 0.521531100478469 0.899063579847418 0.980386097879288 GO:1990782 protein tyrosine kinase binding 1/361 117/18639 0.00854700854700855 0.441295546558705 0.899289792686179 0.980386097879288 GO:0022853 active monoatomic ion transmembrane transporter activity 1/361 118/18639 0.00847457627118644 0.437555753791258 0.901252668446912 0.980386097879288 GO:0005126 cytokine receptor binding 3/361 275/18639 0.0109090909090909 0.563253588516746 0.904174982239725 0.980386097879288 GO:0004540 RNA nuclease activity 1/361 121/18639 0.00826446280991736 0.426707264027838 0.906915320592858 0.980386097879288 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/361 122/18639 0.00819672131147541 0.42320966350302 0.90872996414324 0.980386097879288 GO:0141003 histone H2AX kinase activity 4/361 354/18639 0.0112994350282486 0.583407671721677 0.914598715230458 0.980386097879288 GO:0045182 translation regulator activity 4/361 356/18639 0.0112359550561798 0.580130100532229 0.916727003100989 0.980386097879288 GO:0004519 endonuclease activity 1/361 127/18639 0.0078740157480315 0.40654786572731 0.917287472029633 0.980386097879288 GO:0140996 histone H3 kinase activity 4/361 357/18639 0.0112044817927171 0.578505086245024 0.91777332616605 0.980386097879288 GO:0035173 histone kinase activity 4/361 360/18639 0.0111111111111111 0.573684210526316 0.920842292388779 0.980386097879288 GO:0106310 protein serine kinase activity 4/361 361/18639 0.0110803324099723 0.57209505758857 0.921842299669054 0.980386097879288 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 1/361 130/18639 0.00769230769230769 0.397165991902834 0.922032871405778 0.980386097879288 GO:0005262 calcium channel activity 1/361 131/18639 0.00763358778625954 0.394134190437927 0.923553544236429 0.980386097879288 GO:0004674 protein serine/threonine kinase activity 5/361 433/18639 0.0115473441108545 0.596207609092014 0.924823174523583 0.980386097879288 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 1/361 132/18639 0.00757575757575758 0.391148325358852 0.925044638386561 0.980386097879288 GO:0015297 antiporter activity 1/361 135/18639 0.00740740740740741 0.382456140350877 0.929346131161786 0.980386097879288 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 2/361 229/18639 0.00873362445414847 0.450930820501034 0.938424334454443 0.980386097879288 GO:0005125 cytokine activity 2/361 234/18639 0.00854700854700855 0.441295546558705 0.943217507303213 0.980386097879288 GO:0015085 calcium ion transmembrane transporter activity 1/361 147/18639 0.00680272108843537 0.351235230934479 0.944226630532051 0.980386097879288 GO:0008509 monoatomic anion transmembrane transporter activity 1/361 149/18639 0.00671140939597315 0.346520664076298 0.946383043125277 0.980386097879288 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 2/361 243/18639 0.00823045267489712 0.42495126705653 0.950965691260036 0.980386097879288 GO:0004676 3-phosphoinositide-dependent protein kinase activity 2/361 245/18639 0.00816326530612245 0.421482277121375 0.952545230797594 0.980386097879288 GO:0004711 ribosomal protein S6 kinase activity 2/361 245/18639 0.00816326530612245 0.421482277121375 0.952545230797594 0.980386097879288 GO:0035175 histone H3S10 kinase activity 2/361 245/18639 0.00816326530612245 0.421482277121375 0.952545230797594 0.980386097879288 GO:0035979 histone H2AXS139 kinase activity 2/361 245/18639 0.00816326530612245 0.421482277121375 0.952545230797594 0.980386097879288 GO:0044022 histone H3S28 kinase activity 2/361 245/18639 0.00816326530612245 0.421482277121375 0.952545230797594 0.980386097879288 GO:0044023 histone H4S1 kinase activity 2/361 245/18639 0.00816326530612245 0.421482277121375 0.952545230797594 0.980386097879288 GO:0044024 histone H2AS1 kinase activity 2/361 245/18639 0.00816326530612245 0.421482277121375 0.952545230797594 0.980386097879288 GO:0044025 histone H2BS14 kinase activity 2/361 245/18639 0.00816326530612245 0.421482277121375 0.952545230797594 0.980386097879288 GO:0072354 histone H3T3 kinase activity 2/361 245/18639 0.00816326530612245 0.421482277121375 0.952545230797594 0.980386097879288 GO:0072371 histone H2AS121 kinase activity 2/361 245/18639 0.00816326530612245 0.421482277121375 0.952545230797594 0.980386097879288 GO:0072518 Rho-dependent protein serine/threonine kinase activity 2/361 245/18639 0.00816326530612245 0.421482277121375 0.952545230797594 0.980386097879288 GO:0140823 histone H2BS36 kinase activity 2/361 245/18639 0.00816326530612245 0.421482277121375 0.952545230797594 0.980386097879288 GO:0140855 histone H3S57 kinase activity 2/361 245/18639 0.00816326530612245 0.421482277121375 0.952545230797594 0.980386097879288 GO:0140995 histone H2A kinase activity 2/361 245/18639 0.00816326530612245 0.421482277121375 0.952545230797594 0.980386097879288 GO:0140997 histone H4 kinase activity 2/361 245/18639 0.00816326530612245 0.421482277121375 0.952545230797594 0.980386097879288 GO:0140998 histone H2B kinase activity 2/361 245/18639 0.00816326530612245 0.421482277121375 0.952545230797594 0.980386097879288 GO:1990244 histone H2AT120 kinase activity 2/361 245/18639 0.00816326530612245 0.421482277121375 0.952545230797594 0.980386097879288 GO:0004677 DNA-dependent protein kinase activity 2/361 246/18639 0.00813008130081301 0.419768934531451 0.953316694516747 0.980386097879288 GO:0140857 histone H3T45 kinase activity 2/361 246/18639 0.00813008130081301 0.419768934531451 0.953316694516747 0.980386097879288 GO:0035402 histone H3T11 kinase activity 2/361 247/18639 0.00809716599190283 0.418069465160878 0.954076187951129 0.980386097879288 GO:0035403 histone H3T6 kinase activity 2/361 247/18639 0.00809716599190283 0.418069465160878 0.954076187951129 0.980386097879288 GO:0004679 AMP-activated protein kinase activity 2/361 248/18639 0.00806451612903226 0.416383701188455 0.954823883670779 0.980386097879288 GO:0015081 sodium ion transmembrane transporter activity 1/361 164/18639 0.00609756097560976 0.314826700898588 0.960115229964859 0.984269072228126 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 1/361 167/18639 0.00598802395209581 0.309171131421368 0.962407999671024 0.985070668423089 GO:0003823 antigen binding 1/361 174/18639 0.00574712643678161 0.296733212341198 0.967259510608136 0.986792582957428 GO:0061630 ubiquitin protein ligase activity 3/361 353/18639 0.0084985835694051 0.438795288504548 0.968792348808886 0.986792582957428 GO:0005319 lipid transporter activity 1/361 178/18639 0.00561797752808989 0.290065050266115 0.969745967555557 0.986792582957428 GO:0016791 phosphatase activity 2/361 273/18639 0.00732600732600733 0.378253325621747 0.970144241833913 0.986792582957428 GO:0046873 metal ion transmembrane transporter activity 4/361 450/18639 0.00888888888888889 0.458947368421053 0.976288231122412 0.990229460363878 GO:0061659 ubiquitin-like protein ligase activity 3/361 372/18639 0.00806451612903226 0.416383701188455 0.976560648794438 0.990229460363878 GO:0001664 G protein-coupled receptor binding 2/361 297/18639 0.00673400673400673 0.347687400318979 0.980064986560381 0.992239706890324 GO:0008168 methyltransferase activity 1/361 204/18639 0.00490196078431373 0.253095975232198 0.981901699148814 0.992557996658956 GO:0016741 transferase activity, transferring one-carbon groups 1/361 215/18639 0.00465116279069767 0.240146878824969 0.985440903995575 0.99459360589027 GO:0004842 ubiquitin-protein transferase activity 3/361 449/18639 0.0066815144766147 0.344977142187317 0.992945351595249 0.99880722663636 GO:0019787 ubiquitin-like protein transferase activity 3/361 479/18639 0.00626304801670146 0.323371058125481 0.995647518193817 0.99880722663636 GO:0016755 aminoacyltransferase activity 3/361 496/18639 0.00604838709677419 0.312287775891341 0.996700350088691 0.99880722663636 GO:0030371 translation repressor activity 1/361 329/18639 0.00303951367781155 0.156934890417533 0.998485161021211 0.99880722663636 GO:0005216 monoatomic ion channel activity 2/361 448/18639 0.00446428571428571 0.230498120300752 0.998584494377431 0.99880722663636 GO:0005261 monoatomic cation channel activity 1/361 341/18639 0.00293255131964809 0.15141225497762 0.99880722663636 0.99880722663636