ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0003735 structural constituent of ribosome 44/129 175/18639 0.251428571428571 36.3285049833887 6.50270626341054e-58 1.84026587254518e-55 GO:0023026 MHC class II protein complex binding 8/129 27/18639 0.296296296296296 42.8113695090439 8.4032365391036e-12 1.18905797028316e-09 GO:0023023 MHC protein complex binding 8/129 37/18639 0.216216216216216 31.2407291011942 1.37919999185011e-10 1.30104532564527e-08 GO:0019843 rRNA binding 9/129 65/18639 0.138461538461538 20.0060822898032 6.33483382486391e-10 4.16123321181441e-08 GO:0042605 peptide antigen binding 8/129 45/18639 0.177777777777778 25.6868217054264 7.35200214101485e-10 4.16123321181441e-08 GO:0032395 MHC class II receptor activity 5/129 10/18639 0.5 72.2441860465116 3.60024449326236e-09 1.69811531932208e-07 GO:0042277 peptide binding 13/129 249/18639 0.0522088353413655 7.54356962734659 1.88228428681967e-08 7.60980647385668e-07 GO:0005126 cytokine receptor binding 12/129 275/18639 0.0436363636363636 6.30494714587738 4.73284332133174e-07 1.6742433249211e-05 GO:0008009 chemokine activity 6/129 45/18639 0.133333333333333 19.2651162790698 6.38324042078618e-07 1.96958596378397e-05 GO:1990948 ubiquitin ligase inhibitor activity 4/129 11/18639 0.363636363636364 52.5412262156448 6.95966771655111e-07 1.96958596378397e-05 GO:0140375 immune receptor activity 9/129 156/18639 0.0576923076923077 8.33586762075134 1.39266217748635e-06 3.58293996571489e-05 GO:0055105 ubiquitin-protein transferase inhibitor activity 4/129 15/18639 0.266666666666667 38.5302325581395 2.81756818181845e-06 6.64476496212185e-05 GO:0042379 chemokine receptor binding 6/129 72/18639 0.0833333333333333 12.0406976744186 1.05114532861664e-05 0.000228826252306546 GO:0003823 antigen binding 8/129 174/18639 0.0459770114942529 6.64314354450682 2.86689088303972e-05 0.000579521514214458 GO:0005125 cytokine activity 9/129 234/18639 0.0384615384615385 5.55724508050089 3.68786901771326e-05 0.000663456054293797 GO:0005131 growth hormone receptor binding 3/129 10/18639 0.3 43.346511627907 3.75098829282712e-05 0.000663456054293797 GO:0055106 ubiquitin-protein transferase regulator activity 4/129 36/18639 0.111111111111111 16.0542635658915 0.000108645217643427 0.00180862332900528 GO:0001540 amyloid-beta binding 5/129 83/18639 0.0602409638554217 8.70411880078453 0.000276953866086158 0.00435433022791015 GO:0005504 fatty acid binding 4/129 47/18639 0.0851063829787234 12.2968827313211 0.000310198986609397 0.0046203322742347 GO:0016209 antioxidant activity 5/129 86/18639 0.0581395348837209 8.40048674959437 0.000326758437141039 0.00462363188554571 GO:0071813 lipoprotein particle binding 3/129 32/18639 0.09375 13.5457848837209 0.00138717229181106 0.0178440799355696 GO:0071814 protein-lipid complex binding 3/129 32/18639 0.09375 13.5457848837209 0.00138717229181106 0.0178440799355696 GO:0051427 hormone receptor binding 3/129 34/18639 0.0882352941176471 12.7489740082079 0.00165677778477788 0.0203855701344408 GO:0033293 monocarboxylic acid binding 4/129 79/18639 0.0506329113924051 7.3158669414189 0.00220393235516439 0.0244889201212854 GO:0008199 ferric iron binding 2/129 11/18639 0.181818181818182 26.2706131078224 0.0025094653127819 0.0244889201212854 GO:0015217 ADP transmembrane transporter activity 2/129 11/18639 0.181818181818182 26.2706131078224 0.0025094653127819 0.0244889201212854 GO:0019864 IgG binding 2/129 11/18639 0.181818181818182 26.2706131078224 0.0025094653127819 0.0244889201212854 GO:0042608 T cell receptor binding 2/129 11/18639 0.181818181818182 26.2706131078224 0.0025094653127819 0.0244889201212854 GO:0050786 RAGE receptor binding 2/129 11/18639 0.181818181818182 26.2706131078224 0.0025094653127819 0.0244889201212854 GO:0097371 MDM2/MDM4 family protein binding 2/129 12/18639 0.166666666666667 24.0813953488372 0.00299774357195268 0.0282787143620869 GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity 2/129 13/18639 0.153846153846154 22.2289803220036 0.00352677900700499 0.0311899518432004 GO:0035325 Toll-like receptor binding 2/129 13/18639 0.153846153846154 22.2289803220036 0.00352677900700499 0.0311899518432004 GO:0005347 ATP transmembrane transporter activity 2/129 14/18639 0.142857142857143 20.641196013289 0.00409599294034828 0.0340931177093695 GO:0019763 immunoglobulin receptor activity 2/129 14/18639 0.142857142857143 20.641196013289 0.00409599294034828 0.0340931177093695 GO:0001664 G protein-coupled receptor binding 7/129 297/18639 0.0235690235690236 3.40544984731031 0.00465380503894071 0.037629337886292 GO:0048020 CCR chemokine receptor binding 3/129 50/18639 0.06 8.66930232558139 0.00500748908715611 0.0393644281018105 GO:0005149 interleukin-1 receptor binding 2/129 16/18639 0.125 18.0610465116279 0.00535267128597772 0.0409407019981539 GO:0030169 low-density lipoprotein particle binding 2/129 17/18639 0.117647058823529 16.9986320109439 0.00603900787719435 0.0416838836401464 GO:0036041 long-chain fatty acid binding 2/129 17/18639 0.117647058823529 16.9986320109439 0.00603900787719435 0.0416838836401464 GO:0045236 CXCR chemokine receptor binding 2/129 17/18639 0.117647058823529 16.9986320109439 0.00603900787719435 0.0416838836401464 GO:0046965 nuclear retinoid X receptor binding 2/129 17/18639 0.117647058823529 16.9986320109439 0.00603900787719435 0.0416838836401464 GO:0004601 peroxidase activity 3/129 57/18639 0.0526315789473684 7.6046511627907 0.00721808661029463 0.0486361550169853 GO:0005346 purine ribonucleotide transmembrane transporter activity 2/129 19/18639 0.105263157894737 15.2093023255814 0.00752489984956251 0.0495243408703765 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 3/129 59/18639 0.0508474576271186 7.34686637761135 0.00793981313452306 0.0510674344788642 GO:0045296 cadherin binding 7/129 334/18639 0.0209580838323353 3.02819941512324 0.00866271665888661 0.0544788625436647 GO:0038024 cargo receptor activity 3/129 65/18639 0.0461538461538462 6.66869409660107 0.0103534037821126 0.0636959406595188 GO:0000295 adenine nucleotide transmembrane transporter activity 2/129 23/18639 0.0869565217391304 12.5642062689585 0.0109343719833181 0.0658388781123194 GO:0050840 extracellular matrix binding 3/129 67/18639 0.0447761194029851 6.46962860118015 0.0112422107954003 0.0662822011478811 GO:0048027 mRNA 5'-UTR binding 2/129 24/18639 0.0833333333333333 12.0406976744186 0.0118748263696278 0.0685831808694831 GO:0042974 nuclear retinoic acid receptor binding 2/129 25/18639 0.08 11.5590697674419 0.0128494749037886 0.0713047153149306 GO:0005179 hormone activity 4/129 132/18639 0.0303030303030303 4.3784355179704 0.0134017779918717 0.0713047153149306 GO:0008198 ferrous iron binding 2/129 26/18639 0.0769230769230769 11.1144901610018 0.0138578068633257 0.0713047153149306 GO:0015216 purine nucleotide transmembrane transporter activity 2/129 26/18639 0.0769230769230769 11.1144901610018 0.0138578068633257 0.0713047153149306 GO:0019865 immunoglobulin binding 2/129 26/18639 0.0769230769230769 11.1144901610018 0.0138578068633257 0.0713047153149306 GO:0030247 polysaccharide binding 2/129 26/18639 0.0769230769230769 11.1144901610018 0.0138578068633257 0.0713047153149306 GO:0005044 scavenger receptor activity 2/129 27/18639 0.0740740740740741 10.702842377261 0.014899316861078 0.0752947619943763 GO:0043236 laminin binding 2/129 29/18639 0.0689655172413793 9.96471531676022 0.0170798758088865 0.0831560820048532 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 2/129 29/18639 0.0689655172413793 9.96471531676022 0.0170798758088865 0.0831560820048532 GO:0048306 calcium-dependent protein binding 3/129 80/18639 0.0375 5.41831395348837 0.0180742086902858 0.0831560820048532 GO:0001965 G-protein alpha-subunit binding 2/129 30/18639 0.0666666666666667 9.63255813953488 0.0182179402272117 0.0831560820048532 GO:0015215 nucleotide transmembrane transporter activity 2/129 30/18639 0.0666666666666667 9.63255813953488 0.0182179402272117 0.0831560820048532 GO:0048019 receptor antagonist activity 2/129 30/18639 0.0666666666666667 9.63255813953488 0.0182179402272117 0.0831560820048532 GO:0019209 kinase activator activity 4/129 148/18639 0.027027027027027 3.90509113764928 0.0195757964387364 0.0879357205105145 GO:0019825 oxygen binding 2/129 34/18639 0.0588235294117647 8.49931600547196 0.0230775176148439 0.102045898203138 GO:0004857 enzyme inhibitor activity 7/129 416/18639 0.0168269230769231 2.43129472271914 0.0257624528196094 0.112165756122299 GO:0008083 growth factor activity 4/129 162/18639 0.0246913580246914 3.56761412575366 0.0262162143163843 0.112411949265709 GO:0005539 glycosaminoglycan binding 5/129 242/18639 0.0206611570247934 2.98529694407073 0.0266289206948494 0.112477381442424 GO:0043394 proteoglycan binding 2/129 37/18639 0.0540540540540541 7.81018227529855 0.0270317427373284 0.112499752862705 GO:0033218 amide binding 5/129 247/18639 0.0202429149797571 2.92486583184258 0.0287383477012836 0.11786887535454 GO:0008201 heparin binding 4/129 172/18639 0.0232558139534884 3.36019469983775 0.0316948646586931 0.128137809977288 GO:0030547 signaling receptor inhibitor activity 2/129 44/18639 0.0454545454545455 6.5676532769556 0.0372163919948255 0.148341393444164 GO:0031406 carboxylic acid binding 4/129 187/18639 0.0213903743315508 3.09066036562617 0.041086717724702 0.16149362661237 GO:0043177 organic acid binding 4/129 189/18639 0.0211640211640212 3.05795496493171 0.0424461409216252 0.164551477819451 GO:0015605 organophosphate ester transmembrane transporter activity 2/129 50/18639 0.04 5.77953488372093 0.0469247644301222 0.179455518023305 GO:0005080 protein kinase C binding 2/129 52/18639 0.0384615384615385 5.55724508050089 0.0503453474895268 0.189969777860481 GO:1901505 carbohydrate derivative transmembrane transporter activity 2/129 53/18639 0.0377358490566038 5.45239139973673 0.0520884702586263 0.193961014252516 GO:0031625 ubiquitin protein ligase binding 5/129 302/18639 0.0165562913907285 2.39219159094409 0.0589671745094099 0.215047546423789 GO:0015932 nucleobase-containing compound transmembrane transporter activity 2/129 57/18639 0.0350877192982456 5.06976744186047 0.0592710551980761 0.215047546423789 GO:0003680 minor groove of adenine-thymine-rich DNA binding 1/129 10/18639 0.1 14.4488372093023 0.0671092338627352 0.223434272742989 GO:0003796 lysozyme activity 1/129 10/18639 0.1 14.4488372093023 0.0671092338627352 0.223434272742989 GO:0005345 purine nucleobase transmembrane transporter activity 1/129 10/18639 0.1 14.4488372093023 0.0671092338627352 0.223434272742989 GO:0031720 haptoglobin binding 1/129 10/18639 0.1 14.4488372093023 0.0671092338627352 0.223434272742989 GO:0032356 oxidized DNA binding 1/129 10/18639 0.1 14.4488372093023 0.0671092338627352 0.223434272742989 GO:0042975 peroxisome proliferator activated receptor binding 1/129 10/18639 0.1 14.4488372093023 0.0671092338627352 0.223434272742989 GO:0043422 protein kinase B binding 1/129 10/18639 0.1 14.4488372093023 0.0671092338627352 0.223434272742989 GO:0070851 growth factor receptor binding 3/129 139/18639 0.0215827338129496 3.11845407395014 0.0721192069908298 0.23393355767548 GO:0044389 ubiquitin-like protein ligase binding 5/129 322/18639 0.015527950310559 2.24360826231403 0.0732277125351902 0.23393355767548 GO:0015205 nucleobase transmembrane transporter activity 1/129 11/18639 0.0909090909090909 13.1353065539112 0.0735692107177305 0.23393355767548 GO:0050998 nitric-oxide synthase binding 1/129 11/18639 0.0909090909090909 13.1353065539112 0.0735692107177305 0.23393355767548 GO:0020037 heme binding 3/129 142/18639 0.0211267605633803 3.0525712414019 0.0758135628456485 0.238391536503539 GO:0004859 phospholipase inhibitor activity 1/129 12/18639 0.0833333333333333 12.0406976744186 0.0799847986400738 0.240805298033414 GO:0004875 complement receptor activity 1/129 12/18639 0.0833333333333333 12.0406976744186 0.0799847986400738 0.240805298033414 GO:0016840 carbon-nitrogen lyase activity 1/129 12/18639 0.0833333333333333 12.0406976744186 0.0799847986400738 0.240805298033414 GO:0035259 nuclear glucocorticoid receptor binding 1/129 12/18639 0.0833333333333333 12.0406976744186 0.0799847986400738 0.240805298033414 GO:0097110 scaffold protein binding 2/129 70/18639 0.0285714285714286 4.12823920265781 0.0846997298651789 0.249375846715858 GO:0005172 vascular endothelial growth factor receptor binding 1/129 13/18639 0.0769230769230769 11.1144901610018 0.0863563002761629 0.249375846715858 GO:0008035 high-density lipoprotein particle binding 1/129 13/18639 0.0769230769230769 11.1144901610018 0.0863563002761629 0.249375846715858 GO:0017154 semaphorin receptor activity 1/129 13/18639 0.0769230769230769 11.1144901610018 0.0863563002761629 0.249375846715858 GO:0046906 tetrapyrrole binding 3/129 152/18639 0.0197368421052632 2.85174418604651 0.0887138852987206 0.252207467227839 GO:0005506 iron ion binding 3/129 154/18639 0.0194805194805195 2.81470854726669 0.0913984602370034 0.252207467227839 GO:0005344 oxygen carrier activity 1/129 14/18639 0.0714285714285714 10.3205980066445 0.0926840162250716 0.252207467227839 GO:0008494 translation activator activity 1/129 14/18639 0.0714285714285714 10.3205980066445 0.0926840162250716 0.252207467227839 GO:0044548 S100 protein binding 1/129 14/18639 0.0714285714285714 10.3205980066445 0.0926840162250716 0.252207467227839 GO:0061783 peptidoglycan muralytic activity 1/129 14/18639 0.0714285714285714 10.3205980066445 0.0926840162250716 0.252207467227839 GO:0098631 cell adhesion mediator activity 2/129 76/18639 0.0263157894736842 3.80232558139535 0.0973659565935325 0.259333456942578 GO:0005041 low-density lipoprotein particle receptor activity 1/129 15/18639 0.0666666666666667 9.63255813953488 0.0989682450522911 0.259333456942578 GO:0031386 protein tag activity 1/129 15/18639 0.0666666666666667 9.63255813953488 0.0989682450522911 0.259333456942578 GO:0141047 molecular tag activity 1/129 15/18639 0.0666666666666667 9.63255813953488 0.0989682450522911 0.259333456942578 GO:0005178 integrin binding 3/129 161/18639 0.0186335403726708 2.69232991477683 0.101056287425295 0.262375498544573 GO:0016835 carbon-oxygen lyase activity 2/129 79/18639 0.0253164556962025 3.65793347070945 0.103888623761506 0.263361273036639 GO:0005324 long-chain fatty acid transmembrane transporter activity 1/129 16/18639 0.0625 9.03052325581395 0.105209283303379 0.263361273036639 GO:0008142 oxysterol binding 1/129 16/18639 0.0625 9.03052325581395 0.105209283303379 0.263361273036639 GO:0055102 lipase inhibitor activity 1/129 16/18639 0.0625 9.03052325581395 0.105209283303379 0.263361273036639 GO:0000049 tRNA binding 2/129 80/18639 0.025 3.61220930232558 0.106088993378717 0.263361273036639 GO:0001618 virus receptor activity 2/129 81/18639 0.0246913580246914 3.56761412575366 0.108301967958422 0.266517016802029 GO:0140272 exogenous protein binding 2/129 82/18639 0.024390243902439 3.5241066364152 0.110527271124685 0.267188995097092 GO:0005092 GDP-dissociation inhibitor activity 1/129 17/18639 0.0588235294117647 8.49931600547196 0.111407425517515 0.267188995097092 GO:0008429 phosphatidylethanolamine binding 1/129 17/18639 0.0588235294117647 8.49931600547196 0.111407425517515 0.267188995097092 GO:0003746 translation elongation factor activity 1/129 18/18639 0.0555555555555556 8.02713178294574 0.117562964240973 0.272707531804881 GO:0030228 lipoprotein particle receptor activity 1/129 18/18639 0.0555555555555556 8.02713178294574 0.117562964240973 0.272707531804881 GO:0034185 apolipoprotein binding 1/129 18/18639 0.0555555555555556 8.02713178294574 0.117562964240973 0.272707531804881 GO:0098641 cadherin binding involved in cell-cell adhesion 1/129 18/18639 0.0555555555555556 8.02713178294574 0.117562964240973 0.272707531804881 GO:0008301 DNA binding, bending 1/129 19/18639 0.0526315789473684 7.6046511627907 0.123676190040496 0.274177693843447 GO:0015245 fatty acid transmembrane transporter activity 1/129 19/18639 0.0526315789473684 7.6046511627907 0.123676190040496 0.274177693843447 GO:0042834 peptidoglycan binding 1/129 19/18639 0.0526315789473684 7.6046511627907 0.123676190040496 0.274177693843447 GO:0043395 heparan sulfate proteoglycan binding 1/129 19/18639 0.0526315789473684 7.6046511627907 0.123676190040496 0.274177693843447 GO:1901681 sulfur compound binding 4/129 275/18639 0.0145454545454545 2.10164904862579 0.123791088801458 0.274177693843447 GO:0004197 cysteine-type endopeptidase activity 2/129 88/18639 0.0227272727272727 3.2838266384778 0.12412290872043 0.274177693843447 GO:0008017 microtubule binding 4/129 276/18639 0.0144927536231884 2.09403437815976 0.124978524755494 0.274177693843447 GO:0001972 retinoic acid binding 1/129 20/18639 0.05 7.22441860465116 0.129747391516585 0.280293983199952 GO:0016004 phospholipase activator activity 1/129 20/18639 0.05 7.22441860465116 0.129747391516585 0.280293983199952 GO:0019207 kinase regulator activity 4/129 287/18639 0.0139372822299652 2.01377522080869 0.138355976207797 0.296626827778838 GO:0004602 glutathione peroxidase activity 1/129 23/18639 0.0434782608695652 6.28210313447927 0.147711706792244 0.309647503868185 GO:0005158 insulin receptor binding 1/129 23/18639 0.0434782608695652 6.28210313447927 0.147711706792244 0.309647503868185 GO:0017134 fibroblast growth factor binding 1/129 23/18639 0.0434782608695652 6.28210313447927 0.147711706792244 0.309647503868185 GO:0015149 hexose transmembrane transporter activity 1/129 24/18639 0.0416666666666667 6.0203488372093 0.153617658114966 0.310527123189539 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 1/129 24/18639 0.0416666666666667 6.0203488372093 0.153617658114966 0.310527123189539 GO:0030215 semaphorin receptor binding 1/129 24/18639 0.0416666666666667 6.0203488372093 0.153617658114966 0.310527123189539 GO:0055056 D-glucose transmembrane transporter activity 1/129 24/18639 0.0416666666666667 6.0203488372093 0.153617658114966 0.310527123189539 GO:0060229 lipase activator activity 1/129 24/18639 0.0416666666666667 6.0203488372093 0.153617658114966 0.310527123189539 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 1/129 25/18639 0.04 5.77953488372093 0.159482999082099 0.317842878452352 GO:0120020 cholesterol transfer activity 1/129 25/18639 0.04 5.77953488372093 0.159482999082099 0.317842878452352 GO:0016829 lyase activity 3/129 200/18639 0.015 2.16732558139535 0.161368135810309 0.319350926114108 GO:0008143 poly(A) binding 1/129 26/18639 0.0384615384615385 5.55724508050089 0.165308006770849 0.320425793946235 GO:0015145 monosaccharide transmembrane transporter activity 1/129 26/18639 0.0384615384615385 5.55724508050089 0.165308006770849 0.320425793946235 GO:0050750 low-density lipoprotein particle receptor binding 1/129 26/18639 0.0384615384615385 5.55724508050089 0.165308006770849 0.320425793946235 GO:0008013 beta-catenin binding 2/129 106/18639 0.0188679245283019 2.72619569986836 0.166967784164611 0.321441380398536 GO:0008266 poly(U) RNA binding 1/129 27/18639 0.037037037037037 5.35142118863049 0.171092956382764 0.324961789639746 GO:0008395 steroid hydroxylase activity 1/129 27/18639 0.037037037037037 5.35142118863049 0.171092956382764 0.324961789639746 GO:0051119 sugar transmembrane transporter activity 1/129 28/18639 0.0357142857142857 5.16029900332226 0.17683812125632 0.331425088182374 GO:0051959 dynein light intermediate chain binding 1/129 28/18639 0.0357142857142857 5.16029900332226 0.17683812125632 0.331425088182374 GO:0051861 glycolipid binding 1/129 29/18639 0.0344827586206897 4.98235765838011 0.182543772879442 0.33986768240054 GO:0001968 fibronectin binding 1/129 30/18639 0.0333333333333333 4.81627906976744 0.188210180901933 0.343310699995788 GO:0008187 poly-pyrimidine tract binding 1/129 30/18639 0.0333333333333333 4.81627906976744 0.188210180901933 0.343310699995788 GO:0031210 phosphatidylcholine binding 1/129 30/18639 0.0333333333333333 4.81627906976744 0.188210180901933 0.343310699995788 GO:0001221 transcription coregulator binding 2/129 115/18639 0.0173913043478261 2.51284125379171 0.189245474202625 0.343310699995788 GO:0070325 lipoprotein particle receptor binding 1/129 31/18639 0.032258064516129 4.6609152288072 0.193837613147817 0.34940155745753 GO:0031369 translation initiation factor binding 1/129 32/18639 0.03125 4.51526162790698 0.199426335627607 0.35273533114133 GO:0070717 poly-purine tract binding 1/129 32/18639 0.03125 4.51526162790698 0.199426335627607 0.35273533114133 GO:0120015 sterol transfer activity 1/129 32/18639 0.03125 4.51526162790698 0.199426335627607 0.35273533114133 GO:0140311 protein sequestering activity 1/129 33/18639 0.0303030303030303 4.3784355179704 0.204976612550487 0.360300505290608 GO:0005154 epidermal growth factor receptor binding 1/129 35/18639 0.0285714285714286 4.12823920265781 0.215962877628144 0.377268483757807 GO:0004190 aspartic-type endopeptidase activity 1/129 36/18639 0.0277777777777778 4.01356589147287 0.221399385303158 0.379733491156326 GO:0004869 cysteine-type endopeptidase inhibitor activity 1/129 36/18639 0.0277777777777778 4.01356589147287 0.221399385303158 0.379733491156326 GO:0044390 ubiquitin-like protein conjugating enzyme binding 1/129 36/18639 0.0277777777777778 4.01356589147287 0.221399385303158 0.379733491156326 GO:0070001 aspartic-type peptidase activity 1/129 37/18639 0.027027027027027 3.90509113764928 0.226798486485542 0.386650431779569 GO:0005501 retinoid binding 1/129 38/18639 0.0263157894736842 3.80232558139535 0.232160436557759 0.38949685752535 GO:0019840 isoprenoid binding 1/129 38/18639 0.0263157894736842 3.80232558139535 0.232160436557759 0.38949685752535 GO:0051087 protein-folding chaperone binding 2/129 134/18639 0.0149253731343284 2.15654286706005 0.237359484080835 0.38949685752535 GO:0000217 DNA secondary structure binding 1/129 39/18639 0.0256410256410256 3.70483005366726 0.237485489172352 0.38949685752535 GO:0015297 antiporter activity 2/129 135/18639 0.0148148148148148 2.1405684754522 0.23991640554641 0.38949685752535 GO:0019838 growth factor binding 2/129 136/18639 0.0147058823529412 2.12482900136799 0.242474728425908 0.38949685752535 GO:0015144 carbohydrate transmembrane transporter activity 1/129 40/18639 0.025 3.61220930232558 0.242773896263576 0.38949685752535 GO:0050997 quaternary ammonium group binding 1/129 40/18639 0.025 3.61220930232558 0.242773896263576 0.38949685752535 GO:0071855 neuropeptide receptor binding 1/129 40/18639 0.025 3.61220930232558 0.242773896263576 0.38949685752535 GO:0016922 nuclear receptor binding 2/129 137/18639 0.0145985401459854 2.10931930062808 0.24503431208012 0.38949685752535 GO:0001530 lipopolysaccharide binding 1/129 41/18639 0.024390243902439 3.5241066364152 0.248025908058941 0.38949685752535 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 1/129 41/18639 0.024390243902439 3.5241066364152 0.248025908058941 0.38949685752535 GO:0042169 SH2 domain binding 1/129 41/18639 0.024390243902439 3.5241066364152 0.248025908058941 0.38949685752535 GO:0042287 MHC protein binding 1/129 41/18639 0.024390243902439 3.5241066364152 0.248025908058941 0.38949685752535 GO:0030295 protein kinase activator activity 2/129 139/18639 0.0143884892086331 2.07896938263343 0.250156708387438 0.38949685752535 GO:0004520 DNA endonuclease activity 1/129 42/18639 0.0238095238095238 3.44019933554817 0.253241773090687 0.38949685752535 GO:0042056 chemoattractant activity 1/129 42/18639 0.0238095238095238 3.44019933554817 0.253241773090687 0.38949685752535 GO:0051879 Hsp90 protein binding 1/129 42/18639 0.0238095238095238 3.44019933554817 0.253241773090687 0.38949685752535 GO:0048156 tau protein binding 1/129 43/18639 0.0232558139534884 3.36019469983775 0.258421738207173 0.395315415743946 GO:0005543 phospholipid binding 5/129 497/18639 0.0100603621730382 1.45360535304852 0.261399620082544 0.396751019943244 GO:0019955 cytokine binding 2/129 144/18639 0.0138888888888889 2.00678294573643 0.26297526952802 0.396751019943244 GO:0001223 transcription coactivator binding 1/129 44/18639 0.0227272727272727 3.2838266384778 0.263566048584205 0.396751019943244 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 1/129 46/18639 0.0217391304347826 3.14105156723964 0.273748677527708 0.40989881344096 GO:0015631 tubulin binding 4/129 385/18639 0.0103896103896104 1.50117789187557 0.277056852978562 0.412668891541752 GO:0008514 organic anion transmembrane transporter activity 3/129 269/18639 0.0111524163568773 1.61139448430881 0.285540864834046 0.423078873026361 GO:0030544 Hsp70 protein binding 1/129 51/18639 0.0196078431372549 2.83310533515732 0.298598137208858 0.440121212656806 GO:0030246 carbohydrate binding 3/129 280/18639 0.0107142857142857 1.54808970099668 0.30630575786017 0.447122363417157 GO:0004866 endopeptidase inhibitor activity 2/129 161/18639 0.0124223602484472 1.79488660985122 0.306507909904341 0.447122363417157 GO:0051018 protein kinase A binding 1/129 53/18639 0.0188679245283019 2.72619569986836 0.30830001913555 0.447430284181336 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 1/129 54/18639 0.0185185185185185 2.67571059431525 0.31310090676772 0.452079370486044 GO:0098632 cell-cell adhesion mediator activity 1/129 55/18639 0.0181818181818182 2.62706131078224 0.317868729368041 0.454327527329068 GO:0140313 molecular sequestering activity 1/129 55/18639 0.0181818181818182 2.62706131078224 0.317868729368041 0.454327527329068 GO:0030170 pyridoxal phosphate binding 1/129 56/18639 0.0178571428571429 2.58014950166113 0.322603712897503 0.456484253749967 GO:0170055 lipid transmembrane transporter activity 1/129 56/18639 0.0178571428571429 2.58014950166113 0.322603712897503 0.456484253749967 GO:0030414 peptidase inhibitor activity 2/129 169/18639 0.0118343195266272 1.70992156323104 0.326856203647303 0.4585525799265 GO:0070279 vitamin B6 binding 1/129 57/18639 0.0175438596491228 2.53488372093023 0.327306081784993 0.4585525799265 GO:0001786 phosphatidylserine binding 1/129 59/18639 0.0169491525423729 2.44895545920378 0.336613865750852 0.466969235330839 GO:0004879 nuclear receptor activity 1/129 59/18639 0.0169491525423729 2.44895545920378 0.336613865750852 0.466969235330839 GO:0098531 ligand-modulated transcription factor activity 1/129 60/18639 0.0166666666666667 2.40813953488372 0.341219722118889 0.471049665169003 GO:0043021 ribonucleoprotein complex binding 2/129 177/18639 0.0112994350282486 1.63263697280252 0.347048392629016 0.476770364631123 GO:0005319 lipid transporter activity 2/129 178/18639 0.0112359550561798 1.62346485497779 0.349559272734098 0.477899875283816 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 2/129 181/18639 0.0110497237569061 1.59655659771296 0.357072499897615 0.485824603226082 GO:0004536 DNA nuclease activity 1/129 64/18639 0.015625 2.25763081395349 0.359327989036789 0.486554166973259 GO:0120013 lipid transfer activity 1/129 65/18639 0.0153846153846154 2.22289803220036 0.363777339745497 0.488952981182046 GO:0061135 endopeptidase regulator activity 2/129 184/18639 0.0108695652173913 1.57052578361982 0.364555049573893 0.488952981182046 GO:0008234 cysteine-type peptidase activity 2/129 187/18639 0.0106951871657754 1.54533018281308 0.372004996995957 0.496591576178565 GO:0032934 sterol binding 1/129 68/18639 0.0147058823529412 2.12482900136799 0.37694225681157 0.500819993791898 GO:0008028 monocarboxylic acid transmembrane transporter activity 1/129 70/18639 0.0142857142857143 2.0641196013289 0.385568334550754 0.50988709662553 GO:0005518 collagen binding 1/129 72/18639 0.0138888888888889 2.00678294573643 0.394075899464993 0.518713858365549 GO:0043539 protein serine/threonine kinase activator activity 1/129 73/18639 0.0136986301369863 1.97929276839758 0.398285745372733 0.521828083057794 GO:0003684 damaged DNA binding 1/129 74/18639 0.0135135135135135 1.95254556882464 0.402466567243191 0.524875753593655 GO:0044183 protein folding chaperone 1/129 75/18639 0.0133333333333333 1.92651162790698 0.406618563624857 0.527858043604746 GO:0051536 iron-sulfur cluster binding 1/129 76/18639 0.0131578947368421 1.90116279069767 0.410741931718608 0.530776103545051 GO:0051540 metal cluster binding 1/129 77/18639 0.012987012987013 1.87647236484446 0.414836867386781 0.53363106122936 GO:0005516 calmodulin binding 2/129 207/18639 0.00966183574879227 1.39602291877317 0.420711728934638 0.538739453794129 GO:0008135 translation factor activity, RNA binding 1/129 83/18639 0.0120481927710843 1.74082376015691 0.438820202352505 0.559396924620536 GO:0180051 translation factor activity 1/129 84/18639 0.0119047619047619 1.72009966777409 0.442721484627593 0.561839372868201 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 1/129 86/18639 0.0116279069767442 1.68009734991888 0.450443495456212 0.569087094705839 GO:0003727 single-stranded RNA binding 1/129 89/18639 0.0112359550561798 1.62346485497779 0.461827871889333 0.580876834420806 GO:0061134 peptidase regulator activity 2/129 226/18639 0.00884955752212389 1.27865816011525 0.465165562700457 0.582486080726678 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 1/129 91/18639 0.010989010989011 1.58778430871454 0.469287135366564 0.5824923653892 GO:0072341 modified amino acid binding 1/129 91/18639 0.010989010989011 1.58778430871454 0.469287135366564 0.5824923653892 GO:0043178 alcohol binding 1/129 92/18639 0.0108695652173913 1.57052578361982 0.472978204998746 0.584510183470066 GO:0051213 dioxygenase activity 1/129 93/18639 0.010752688172043 1.5536384096024 0.476643801135866 0.586479111832392 GO:0004867 serine-type endopeptidase inhibitor activity 1/129 95/18639 0.0105263157894737 1.52093023255814 0.483899269493186 0.592828975179963 GO:0004896 cytokine receptor activity 1/129 96/18639 0.0104166666666667 1.50508720930233 0.487489487042548 0.59465312428035 GO:0030527 structural constituent of chromatin 1/129 98/18639 0.0102040816326531 1.47437114380636 0.494595743424185 0.600732169051693 GO:0004497 monooxygenase activity 1/129 106/18639 0.00943396226415094 1.36309784993418 0.522056238272691 0.631375706970819 GO:0005496 steroid binding 1/129 108/18639 0.00925925925925926 1.33785529715762 0.528686769915891 0.634203846924476 GO:0019887 protein kinase regulator activity 2/129 255/18639 0.00784313725490196 1.13324213406293 0.529008796979809 0.634203846924476 GO:0003713 transcription coactivator activity 2/129 256/18639 0.0078125 1.12881540697674 0.53111770926184 0.634203846924476 GO:1902936 phosphatidylinositol bisphosphate binding 1/129 111/18639 0.00900900900900901 1.30169704588309 0.538461803284111 0.638725379014351 GO:0005200 structural constituent of cytoskeleton 1/129 112/18639 0.00892857142857143 1.29007475083056 0.541675233086376 0.638725379014351 GO:0043022 ribosome binding 1/129 112/18639 0.00892857142857143 1.29007475083056 0.541675233086376 0.638725379014351 GO:0017124 SH3 domain binding 1/129 115/18639 0.00869565217391304 1.25642062689585 0.551182923879254 0.647239698995141 GO:0009055 electron transfer activity 1/129 116/18639 0.00862068965517241 1.24558941459503 0.554308458473272 0.648220222098909 GO:1990782 protein tyrosine kinase binding 1/129 117/18639 0.00854700854700855 1.23494335122242 0.557412394599004 0.649167521281968 GO:0005096 GTPase activator activity 2/129 271/18639 0.00738007380073801 1.06633484939501 0.561981856366977 0.651806825212518 GO:0004519 endonuclease activity 1/129 127/18639 0.0078740157480315 1.1377037172679 0.587295927512004 0.67591866467051 GO:0035091 phosphatidylinositol binding 2/129 284/18639 0.00704225352112676 1.01752374713397 0.587547673176486 0.67591866467051 GO:0015291 secondary active transmembrane transporter activity 2/129 287/18639 0.00696864111498258 1.00688761040434 0.59329002700393 0.677227105340191 GO:0003779 actin binding 3/129 443/18639 0.00677200902934537 0.978476560449367 0.595043554964789 0.677227105340191 GO:0016798 hydrolase activity, acting on glycosyl bonds 1/129 130/18639 0.00769230769230769 1.11144901610018 0.595864131553737 0.677227105340191 GO:0031072 heat shock protein binding 1/129 131/18639 0.00763358778625954 1.10296467246583 0.59868078977566 0.677706654026047 GO:0002020 protease binding 1/129 136/18639 0.00735294117647059 1.06241450068399 0.612474543690694 0.690558947667197 GO:0019842 vitamin binding 1/129 150/18639 0.00666666666666667 0.963255813953488 0.64864420716309 0.728437740583947 GO:0140297 DNA-binding transcription factor binding 3/129 488/18639 0.00614754098360656 0.888248189096454 0.660368601371349 0.735900008236892 GO:0030695 GTPase regulator activity 3/129 489/18639 0.00613496932515337 0.886431730632045 0.661731308716988 0.735900008236892 GO:0060589 nucleoside-triphosphatase regulator activity 3/129 490/18639 0.00612244897959184 0.884622686283816 0.663090113429001 0.735900008236892 GO:0003924 GTPase activity 2/129 331/18639 0.00604229607250755 0.873041523220684 0.670739513415602 0.741481571471154 GO:0140097 catalytic activity, acting on DNA 2/129 336/18639 0.00595238095238095 0.860049833887043 0.678748933510432 0.747416140791643 GO:0005201 extracellular matrix structural constituent 1/129 168/18639 0.00595238095238095 0.860049833887043 0.690266321340441 0.757152592788159 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 2/129 349/18639 0.00573065902578797 0.828013593656294 0.698837890239879 0.763595069258246 GO:0004252 serine-type endopeptidase activity 1/129 176/18639 0.00568181818181818 0.82095665961945 0.707157540581279 0.769713784555777 GO:0015078 proton transmembrane transporter activity 1/129 185/18639 0.00540540540540541 0.781018227529856 0.725069639560254 0.783185908379969 GO:1901981 phosphatidylinositol phosphate binding 1/129 185/18639 0.00540540540540541 0.781018227529856 0.725069639560254 0.783185908379969 GO:0046943 carboxylic acid transmembrane transporter activity 1/129 188/18639 0.00531914893617021 0.768555170707571 0.73079532007586 0.785408037094907 GO:0005342 organic acid transmembrane transporter activity 1/129 189/18639 0.00529100529100529 0.764488741232927 0.732677462166274 0.785408037094907 GO:0008236 serine-type peptidase activity 1/129 194/18639 0.00515463917525773 0.744785423159914 0.741894095981231 0.792286902500711 GO:0017171 serine hydrolase activity 1/129 198/18639 0.00505050505050505 0.729739252995067 0.749039803958201 0.796910768872823 GO:0004518 nuclease activity 1/129 209/18639 0.00478468899521531 0.691331923890063 0.767694149775708 0.810662105919871 GO:0051015 actin filament binding 1/129 209/18639 0.00478468899521531 0.691331923890063 0.767694149775708 0.810662105919871 GO:0004175 endopeptidase activity 2/129 405/18639 0.00493827160493827 0.713522825150732 0.773842906904738 0.814117258936955 GO:0005085 guanyl-nucleotide exchange factor activity 1/129 230/18639 0.00434782608695652 0.628210313447927 0.799569208538487 0.838066985245895 GO:0140104 molecular carrier activity 1/129 249/18639 0.00401606425702811 0.580274586718969 0.824648359351532 0.861164153861563 GO:0022804 active transmembrane transporter activity 2/129 457/18639 0.00437636761487965 0.632334232354588 0.828463771049891 0.861967820614409 GO:0003730 mRNA 3'-UTR binding 1/129 262/18639 0.00381679389312977 0.551482336232913 0.839987625773261 0.870756403274113 GO:0016791 phosphatase activity 1/129 273/18639 0.00366300366300366 0.52926143623818 0.85192163740769 0.879904464913782 GO:0003712 transcription coregulator activity 2/129 495/18639 0.00404040404040404 0.583791402396054 0.860605913173524 0.885641721556754 GO:0045182 translation regulator activity 1/129 356/18639 0.00280898876404494 0.405866213744447 0.91761605449351 0.940888925440809 GO:0042578 phosphoric ester hydrolase activity 1/129 363/18639 0.00275482093663912 0.398039592542764 0.921600526768381 0.941497420633878 GO:0046982 protein heterodimerization activity 1/129 369/18639 0.002710027100271 0.391567404046133 0.924863190587343 0.941497420633878 GO:0005525 GTP binding 1/129 378/18639 0.00264550264550265 0.382244370616464 0.929506228573814 0.942832482746915 GO:0019001 guanyl nucleotide binding 1/129 400/18639 0.0025 0.361220930232558 0.939691709824461 0.946379907047411 GO:0032561 guanyl ribonucleotide binding 1/129 400/18639 0.0025 0.361220930232558 0.939691709824461 0.946379907047411 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 1/129 484/18639 0.00206611570247934 0.298529694407073 0.966822183557234 0.968437892217106 GO:0001216 DNA-binding transcription activator activity 1/129 491/18639 0.00203665987780041 0.294273670250557 0.968437892217106 0.968437892217106