category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	26/109	238/9376	9.39696245470665	C3/IL1B/RPL37A/RPL21/RPL13A/RPL17/RPL22/RPS18/RPSA/RPL29/RPL12/RPL35A/RPL6/NRP1/RPS24/RPS16/RPL18A/TNF/RPS3A/RPL14/RPS7/RPL3/RPL30/C1R/RPL36/NLRP3	14.230311887019
Genetic Information Processing	Translation	hsa03010	Ribosome	20/109	222/9376	7.74940077692371	RPL37A/RPL21/RPL13A/RPL17/RPL22/RPS18/RPSA/RPL29/RPL12/RPL35A/RPL6/RPS24/RPS16/RPL18A/RPS3A/RPL14/RPS7/RPL3/RPL30/RPL36	11.0373688454176
Human Diseases	Immune disease	hsa05323	Rheumatoid arthritis	9/109	95/9376	8.14910671173346	CXCL3/CCL3L1/IL1B/CXCL2/CCL3/HLA-DRB5/IL1A/TNF/CCL3L3	7.59530995580096
Environmental Information Processing	Signaling molecules and interaction	hsa04061	Viral protein interaction with cytokine and cytokine receptor	9/109	100/9376	7.74165137614679	CXCL3/CCL3L1/CXCL2/CCL3/CCL4L2/CXCR4/TNF/CXCL14/CCL3L3	7.35047197727606
Environmental Information Processing	Signal transduction	hsa04064	NF-kappa B signaling pathway	8/109	105/9376	6.55377894276977	CXCL3/IL1B/CXCL2/CCL4L2/PTGS2/PLAU/TNF/GADD45B	6.20653564830567
Human Diseases	Infectious disease: parasitic	hsa05140	Leishmaniasis	7/109	78/9376	7.71959538932016	C3/IL1B/EEF1A1/HLA-DRB5/PTGS2/IL1A/TNF	6.46286314405728
Environmental Information Processing	Signaling molecules and interaction	hsa04060	Cytokine-cytokine receptor interaction	13/109	298/9376	3.75247829567145	CSH2/CSH1/CXCL3/CCL3L1/IL1B/CXCL2/CCL3/CCL4L2/CXCR4/IL1A/TNF/CXCL14/CCL3L3	5.23680317868209
Human Diseases	Infectious disease: bacterial	hsa05134	Legionellosis	6/109	56/9376	9.21625163826999	C3/CXCL3/IL1B/CXCL2/EEF1A1/TNF	6.68788959189881
Human Diseases	Cardiovascular disease	hsa05417	Lipid and atherosclerosis	10/109	216/9376	3.98233095480802	CXCL3/CCL3L1/IL1B/CXCL2/CCL3/ABCA1/OLR1/TNF/CCL3L3/NLRP3	4.80910523559263
Organismal Systems	Immune system	hsa04620	Toll-like receptor signaling pathway	7/109	109/9376	5.52411413180709	SPP1/CCL3L1/IL1B/CCL3/CCL4L2/TNF/CCL3L3	5.15236386393256
Human Diseases	Infectious disease: bacterial	hsa05133	Pertussis	6/109	78/9376	6.61679604798871	C3/IL1B/IL1A/TNF/C1R/NLRP3	5.40219790970263
Organismal Systems	Immune system	hsa04610	Complement and coagulation cascades	6/109	88/9376	5.86488740617181	C3/PLAUR/A2M/PLAU/THBD/C1R	4.97258632966897
Organismal Systems	Immune system	hsa04657	IL-17 signaling pathway	6/109	94/9376	5.49053289088425	CXCL3/IL1B/CXCL2/FOSB/PTGS2/TNF	4.74537275129885
Human Diseases	Infectious disease: parasitic	hsa05142	Chagas disease	6/109	103/9376	5.01077758973902	C3/CCL3L1/IL1B/CCL3/TNF/CCL3L3	4.43880807855205
Human Diseases	Endocrine and metabolic disease	hsa04940	Type I diabetes mellitus	4/109	44/9376	7.81984987489575	IL1B/HLA-DRB5/IL1A/TNF	4.91748556215459
Human Diseases	Immune disease	hsa05332	Graft-versus-host disease	4/109	45/9376	7.6460754332314	IL1B/HLA-DRB5/IL1A/TNF	4.84659504611059
Organismal Systems	Immune system	hsa04062	Chemokine signaling pathway	8/109	193/9376	3.56552740409754	CXCL3/CCL3L1/CXCL2/CCL3/CCL4L2/CXCR4/CXCL14/CCL3L3	3.90564104357616
Cellular Processes	Transport and catabolism	hsa04145	Phagosome	7/109	155/9376	3.88469961527079	C3/HLA-DRB5/CORO1A/OLR1/MSR1/ITGB5/C1R	3.92741451037813
Organismal Systems	Digestive system	hsa04979	Cholesterol metabolism	4/109	52/9376	6.61679604798871	ABCA1/PLTP/LPL/LRPAP1	4.40472195936261
Metabolism	Amino acid metabolism	hsa00270	Cysteine and methionine metabolism	4/109	54/9376	6.37172952769283	SDS/LDHB/SMS/MAT2A	4.29324599670598
Human Diseases	Infectious disease: viral	hsa05163	Human cytomegalovirus infection	8/109	227/9376	3.03148365194196	CCL3L1/IL1B/CCL3/CCL4L2/CXCR4/PTGS2/TNF/CCL3L3	3.36022804521073
Human Diseases	Infectious disease: bacterial	hsa05152	Tuberculosis	7/109	181/9376	3.32667646611587	C3/IL1B/HLA-DRB5/CORO1A/IL1A/CTSD/TNF	3.42790457271107
Human Diseases	Cardiovascular disease	hsa05418	Fluid shear stress and atherosclerosis	6/109	142/9376	3.63457811086704	IL1B/MEF2C/MGST1/IL1A/THBD/TNF	3.43075434431552
Human Diseases	Endocrine and metabolic disease	hsa04933	AGE-RAGE signaling pathway in diabetic complications	5/109	101/9376	4.25833409028976	IL1B/EGR1/IL1A/THBD/TNF	3.57049677917338
Organismal Systems	Endocrine system	hsa04929	GnRH secretion	4/109	65/9376	5.29343683839097	CGA/SPP1/KCNJ5/KISS1	3.76697639632527
Human Diseases	Immune disease	hsa05321	Inflammatory bowel disease	4/109	66/9376	5.2132332499305	IL1B/HLA-DRB5/IL1A/TNF	3.72513430946776
Organismal Systems	Endocrine system	hsa03320	PPAR signaling pathway	4/109	76/9376	4.52728150651859	PLTP/OLR1/LPL/FABP5	3.3483800747303
Environmental Information Processing	Signal transduction	hsa04668	TNF signaling pathway	5/109	119/9376	3.61421632873333	CXCL3/IL1B/CXCL2/PTGS2/TNF	3.112498691163
Human Diseases	Infectious disease: parasitic	hsa05144	Malaria	3/109	50/9376	5.16110091743119	IL1B/HGF/TNF	3.19944648896225
Organismal Systems	Endocrine system	hsa04913	Ovarian steroidogenesis	3/109	52/9376	4.96259703599153	CGA/PTGS2/CYP19A1	3.1074901120519
Environmental Information Processing	Signal transduction	hsa04010	MAPK signaling pathway	8/109	300/9376	2.29382262996942	IL1B/NR4A1/STMN1/MEF2C/IL1A/HGF/TNF/GADD45B	2.47011647569864
Human Diseases	Endocrine and metabolic disease	hsa04936	Alcoholic liver disease	5/109	144/9376	2.98674821610601	C3/CXCL3/IL1B/CXCL2/TNF	2.60558644079748
Organismal Systems	Immune system	hsa04640	Hematopoietic cell lineage	4/109	100/9376	3.44073394495413	IL1B/HLA-DRB5/IL1A/TNF	2.66115013449802
Human Diseases	Cancer: overview	hsa05205	Proteoglycans in cancer	6/109	204/9376	2.52995143011333	PLAUR/DCN/PLAU/HGF/TNF/ITGB5	2.39601763533659
Human Diseases	Infectious disease: parasitic	hsa05146	Amoebiasis	4/109	103/9376	3.34051839315935	CXCL3/IL1B/CXCL2/TNF	2.5902986937332
NA	NA	hsa04518	Integrin signaling	5/109	154/9376	2.79280352674848	SPP1/C3/ICAM4/HGF/ITGB5	2.43281903395877
Organismal Systems	Immune system	hsa04625	C-type lectin receptor signaling pathway	4/109	105/9376	3.27688947138488	IL1B/PTGS2/TNF/NLRP3	2.54450092757103
Cellular Processes	Transport and catabolism	hsa04148	Efferocytosis	5/109	157/9376	2.73943785426284	MERTK/PTGS2/ABCA1/AXL/ITGB5	2.38367005953697
Human Diseases	Drug resistance: antineoplastic	hsa01523	Antifolate resistance	2/109	30/9376	5.73455657492355	IL1B/TNF	2.81680222514916
Human Diseases	Infectious disease: viral	hsa05164	Influenza A	5/109	173/9376	2.48607943999576	IL1B/HLA-DRB5/IL1A/TNF/NLRP3	2.1395856277326
Human Diseases	Immune disease	hsa05310	Asthma	2/109	32/9376	5.37614678899083	HLA-DRB5/TNF	2.68924123019689
Organismal Systems	Immune system	hsa04621	NOD-like receptor signaling pathway	5/109	187/9376	2.29995584555757	CXCL3/IL1B/CXCL2/TNF/NLRP3	1.94735255371509
Human Diseases	Infectious disease: parasitic	hsa05143	African trypanosomiasis	2/109	37/9376	4.64964046615423	IL1B/TNF	2.41229303711579
Organismal Systems	Immune system	hsa04612	Antigen processing and presentation	3/109	82/9376	3.14701275453121	LGMN/HLA-DRB5/TNF	2.11772479835109
Organismal Systems	Immune system	hsa04623	Cytosolic DNA-sensing pathway	3/109	83/9376	3.10909693821156	IL1B/CCL4L2/NLRP3	2.09308528500112
Human Diseases	Immune disease	hsa05330	Allograft rejection	2/109	39/9376	4.41119736532581	HLA-DRB5/TNF	2.31507346587179
Organismal Systems	Development and regeneration	hsa04380	Osteoclast differentiation	4/109	142/9376	2.42305207391136	IL1B/FOSB/IL1A/TNF	1.85310204492358
Human Diseases	Immune disease	hsa05322	Systemic lupus erythematosus	4/109	143/9376	2.40610765381408	C3/HLA-DRB5/TNF/C1R	1.83757248303559
Organismal Systems	Endocrine system	hsa04925	Aldosterone synthesis and secretion	3/109	98/9376	2.63321475379143	NR4A2/NR4A1/KCNJ5	1.76261902707005
Human Diseases	Infectious disease: bacterial	hsa05150	Staphylococcus aureus infection	3/109	99/9376	2.60661662496525	C3/HLA-DRB5/C1R	1.74283142182083
NA	NA	hsa04081	Hormone signaling	5/109	219/9376	1.96388923798752	CGA/CSH2/CSH1/SLC40A1/SLC16A10	1.56531550571439
Organismal Systems	Immune system	hsa04672	Intestinal immune network for IgA production	2/109	50/9376	3.44073394495413	CXCR4/HLA-DRB5	1.8766662490597
Environmental Information Processing	Signal transduction	hsa04151	PI3K-Akt signaling pathway	7/109	362/9376	1.66333823305793	SPP1/CSH2/CSH1/NR4A1/DDIT4/HGF/ITGB5	1.39591779511929
Human Diseases	Immune disease	hsa05320	Autoimmune thyroid disease	2/109	54/9376	3.18586476384642	CGA/HLA-DRB5	1.74700812807955
Cellular Processes	Cell growth and death	hsa04217	Necroptosis	4/109	168/9376	2.04805591961555	IL1B/IL1A/TNF/NLRP3	1.48657130862836
Environmental Information Processing	Signal transduction	hsa04350	TGF-beta signaling pathway	3/109	110/9376	2.34595496246872	DCN/SKIL/TNF	1.53996208506583
Organismal Systems	Endocrine system	hsa04928	Parathyroid hormone synthesis, secretion and action	3/109	115/9376	2.24395692062226	EGR1/NR4A2/MEF2C	1.45564215562142
Metabolism	Metabolism of other amino acids	hsa00480	Glutathione metabolism	2/109	59/9376	2.9158762245374	MGST1/SMS	1.6009755952519
Organismal Systems	Endocrine system	hsa04923	Regulation of lipolysis in adipocytes	2/109	59/9376	2.9158762245374	CGA/PTGS2	1.6009755952519
Human Diseases	Infectious disease: viral	hsa05168	Herpes simplex virus 1 infection	4/109	180/9376	1.91151885830785	C3/IL1B/HLA-DRB5/TNF	1.33915773782571
Cellular Processes	Transport and catabolism	hsa04142	Lysosome biogenesis	5/109	250/9376	1.72036697247706	LGMN/SLC11A1/PSAP/CTSD/AP1B1	1.25202462511551
Human Diseases	Infectious disease: viral	hsa05167	Kaposi sarcoma-associated herpesvirus infection	4/109	196/9376	1.75547650252762	C3/CXCL3/CXCL2/PTGS2	1.15919623479522
Human Diseases	Cancer: overview	hsa05204	Chemical carcinogenesis - DNA adducts	2/109	70/9376	2.45766710353866	PTGS2/MGST1	1.32756304433652
Human Diseases	Infectious disease: bacterial	hsa05120	Epithelial cell signaling in Helicobacter pylori infection	2/109	71/9376	2.42305207391136	CXCL3/CXCL2	1.30533229770492
Human Diseases	Infectious disease: bacterial	hsa05130	Pathogenic Escherichia coli infection	4/109	200/9376	1.72036697247706	IL1B/MYO5A/TNF/NLRP3	1.11678968501826
Human Diseases	Cancer: overview	hsa05202	Transcriptional misregulation in cancer	4/109	201/9376	1.711807932813	MEF2C/PLAU/FUS/GADD45B	1.10633619651956
Genetic Information Processing	Information processing in viruses	hsa03250	Viral life cycle - HIV-1	2/109	73/9376	2.35666708558502	CXCR4/ELL2	1.26198012098466
Human Diseases	Cancer: specific types	hsa05218	Melanoma	2/109	73/9376	2.35666708558502	HGF/GADD45B	1.26198012098466
Human Diseases	Cancer: specific types	hsa05223	Non-small cell lung cancer	2/109	73/9376	2.35666708558502	HGF/GADD45B	1.26198012098466
Cellular Processes	Cell growth and death	hsa04210	Apoptosis	3/109	137/9376	1.88361347351503	CTSD/TNF/GADD45B	1.12989850792997
Human Diseases	Infectious disease: viral	hsa05169	Epstein-Barr virus infection	4/109	205/9376	1.67840680241665	HLA-DRB5/VIM/TNF/GADD45B	1.06509435621594
Human Diseases	Infectious disease: bacterial	hsa05135	Yersinia infection	3/109	138/9376	1.86996410051855	IL1B/TNF/NLRP3	1.11655777877239
Metabolism	Global and overview maps	hsa01230	Biosynthesis of amino acids	2/109	75/9376	2.29382262996942	SDS/MAT2A	1.22002816915516
Human Diseases	Drug resistance: antineoplastic	hsa01524	Platinum drug resistance	2/109	75/9376	2.29382262996942	MGST1/REV3L	1.22002816915516
Environmental Information Processing	Signal transduction	hsa04371	Apelin signaling pathway	3/109	140/9376	1.843250327654	SPP1/EGR1/MEF2C	1.09020427324396
Human Diseases	Drug resistance: antineoplastic	hsa01521	EGFR tyrosine kinase inhibitor resistance	2/109	80/9376	2.15045871559633	HGF/AXL	1.12072040748891
Metabolism	Glycan biosynthesis and metabolism	hsa00534	Glycosaminoglycan biosynthesis - heparan sulfate / heparin	1/109	24/9376	3.58409785932722	HS3ST1	1.37464840889396
Human Diseases	Infectious disease: viral	hsa05166	Human T-cell leukemia virus 1 infection	4/109	224/9376	1.53604193971166	EGR1/HLA-DRB5/NRP1/TNF	0.880631222470504
Organismal Systems	Endocrine system	hsa04921	Oxytocin signaling pathway	3/109	154/9376	1.67568211604909	PTGS2/MEF2C/KCNJ5	0.916894845589165
Human Diseases	Endocrine and metabolic disease	hsa04932	Non-alcoholic fatty liver disease	3/109	157/9376	1.6436627125577	IL1B/IL1A/TNF	0.882054815930382
Environmental Information Processing	Signaling molecules and interaction	hsa04512	ECM-receptor interaction	2/109	89/9376	1.93299659828884	SPP1/ITGB5	0.959106085348364
Environmental Information Processing	Signal transduction	hsa04150	mTOR signaling pathway	3/109	158/9376	1.63325978399721	DDIT4/TNF/CAB39	0.870605498472422
Environmental Information Processing	Signaling molecules and interaction	hsa04514	Cell adhesion molecule (CAM) interaction	3/109	160/9376	1.61284403669725	HLA-DRB5/ALCAM/CADM1	0.847945673257802
Organismal Systems	Endocrine system	hsa04912	GnRH signaling pathway	2/109	93/9376	1.84985695965276	CGA/EGR1	0.893248797039099
Human Diseases	Cancer: specific types	hsa05222	Small cell lung cancer	2/109	93/9376	1.84985695965276	PTGS2/GADD45B	0.893248797039099
NA	NA	hsa04981	Folate transport and metabolism	1/109	31/9376	2.77478543947914	SLCO2B1	1.07341177926845
Metabolism	Carbohydrate metabolism	hsa00640	Propanoate metabolism	1/109	32/9376	2.68807339449541	LDHB	1.03735930053717
Human Diseases	Cancer: specific types	hsa05225	Hepatocellular carcinoma	3/109	170/9376	1.517970858068	MGST1/HGF/GADD45B	0.739134726991132
Human Diseases	Cardiovascular disease	hsa05410	Hypertrophic cardiomyopathy	2/109	99/9376	1.7377444166435	TNF/ITGB5	0.80029306968424
Human Diseases	Cancer: overview	hsa05206	MicroRNAs in cancer	5/109	323/9376	1.33155338427017	STMN1/PTGS2/VIM/PLAU/DDIT4	0.657639320430993
Human Diseases	Infectious disease: bacterial	hsa05132	Salmonella infection	4/109	248/9376	1.38739271973957	IL1B/TNF/GCC2/NLRP3	0.670530882940874
Genetic Information Processing	Translation	hsa03015	mRNA surveillance pathway	2/109	103/9376	1.67025919657967	PCF11/FUS	0.741789308914348
Human Diseases	Infectious disease: bacterial	hsa05131	Shigellosis	4/109	253/9376	1.35997389128622	C3/IL1B/TNF/NLRP3	0.629494197964486
Human Diseases	Infectious disease: viral	hsa05165	Human papillomavirus infection	5/109	333/9376	1.29156679615395	SPP1/PTGS2/CHD4/TNF/ITGB5	0.587534294673397
Human Diseases	Cardiovascular disease	hsa05414	Dilated cardiomyopathy	2/109	105/9376	1.63844473569244	TNF/ITGB5	0.713483567203712
Human Diseases	Cancer: specific types	hsa05216	Thyroid cancer	1/109	37/9376	2.32482023307711	GADD45B	0.875662864142244
Genetic Information Processing	Translation	hsa03013	Nucleocytoplasmic transport	2/109	108/9376	1.59293238192321	EEF1A1/AHCTF1	0.672130092563799
Organismal Systems	Immune system	hsa04659	Th17 cell differentiation	2/109	109/9376	1.57831832337345	IL1B/HLA-DRB5	0.65862759965546
Metabolism	Metabolism of cofactors and vitamins	hsa00670	One carbon pool by folate	1/109	39/9376	2.2055986826629	MAT2A	0.81820229726177
Human Diseases	Infectious disease: parasitic	hsa05145	Toxoplasmosis	2/109	112/9376	1.53604193971166	HLA-DRB5/TNF	0.618924698611341
Metabolism	Amino acid metabolism	hsa00260	Glycine, serine and threonine metabolism	1/109	41/9376	2.09800850302081	SDS	0.764134443798597
Organismal Systems	Nervous system	hsa04726	Serotonergic synapse	2/109	115/9376	1.49597128041484	PTGS2/KCNJ5	0.580371146123157
Cellular Processes	Cell growth and death	hsa04216	Ferroptosis	1/109	42/9376	2.04805591961555	SLC40A1	0.73825178868784
Organismal Systems	Digestive system	hsa04975	Fat digestion and absorption	1/109	43/9376	2.00042671218263	ABCA1	0.713079875118165
Human Diseases	Neurodegenerative disease	hsa05020	Prion disease	4/109	275/9376	1.25117597998332	IL1B/EGR1/IL1A/TNF	0.458489295766242
Environmental Information Processing	Membrane transport	hsa02010	ABC transporters	1/109	45/9376	1.91151885830785	ABCA1	0.664717520511686
Organismal Systems	Endocrine system	hsa04935	Growth hormone synthesis, secretion and action	2/109	122/9376	1.41013686268612	CSH2/CSH1	0.49450795050446
Cellular Processes	Cellular community - eukaryotes	hsa04510	Focal adhesion	3/109	203/9376	1.27120712252	SPP1/HGF/ITGB5	0.42366512820275
Metabolism	Carbohydrate metabolism	hsa00620	Pyruvate metabolism	1/109	47/9376	1.83017763029475	LDHB	0.618773512655146
Human Diseases	Endocrine and metabolic disease	hsa04930	Type II diabetes mellitus	1/109	47/9376	1.83017763029475	TNF	0.618773512655146
Environmental Information Processing	Signal transduction	hsa04071	Sphingolipid signaling pathway	2/109	125/9376	1.37629357798165	CTSD/TNF	0.459321503968833
Environmental Information Processing	Signaling molecules and interaction	hsa04080	Neuroactive ligand-receptor interaction	5/109	370/9376	1.16241011653856	CGA/CSH2/C3/CSH1/KISS1	0.345682404644605
Human Diseases	Substance dependence	hsa05030	Cocaine addiction	1/109	49/9376	1.75547650252762	FOSB	0.575012543176158
Metabolism	Amino acid metabolism	hsa00330	Arginine and proline metabolism	1/109	50/9376	1.72036697247706	SMS	0.553886009157147
Metabolism	Lipid metabolism	hsa00565	Ether lipid metabolism	1/109	51/9376	1.68663428674222	PLD4	0.533231085568217
Human Diseases	Infectious disease: viral	hsa05170	Human immunodeficiency virus 1 infection	3/109	214/9376	1.20586470033439	CXCR4/TNF/AP1B1	0.330386986756334
NA	NA	hsa04517	IgSF CAM signaling	4/109	299/9376	1.15074713878064	PMP22/NRP1/CADM1/CD2AP	0.287304752474967
Genetic Information Processing	Replication and repair	hsa03460	Fanconi anemia pathway	1/109	54/9376	1.59293238192321	REV3L	0.473889193766331
Human Diseases	Infectious disease: viral	hsa05162	Measles	2/109	136/9376	1.26497571505666	IL1B/IL1A	0.337573889020522
Human Diseases	Neurodegenerative disease	hsa05010	Alzheimer disease	5/109	388/9376	1.10848387401873	IL1B/PTGS2/IL1A/LPL/TNF	0.236689407381485
Metabolism	Lipid metabolism	hsa00600	Sphingolipid metabolism	1/109	55/9376	1.56396997497915	PSAP	0.454920365864259
Organismal Systems	Endocrine system	hsa04915	Estrogen signaling pathway	2/109	139/9376	1.23767408091875	CTSD/KCNJ5	0.30616324842483
Human Diseases	Cancer: specific types	hsa05213	Endometrial cancer	1/109	59/9376	1.4579381122687	GADD45B	0.382669680059804
Environmental Information Processing	Signal transduction	hsa04370	VEGF signaling pathway	1/109	60/9376	1.43363914373089	PTGS2	0.365442176751592
Cellular Processes	Cell motility	hsa04810	Regulation of actin cytoskeleton	3/109	232/9376	1.112306232205	CXCR4/ITGB5/IQGAP2	0.187849068840813
Organismal Systems	Digestive system	hsa04978	Mineral absorption	1/109	61/9376	1.41013686268612	SLC40A1	0.348523124276768
Cellular Processes	Cell motility	hsa04820	Cytoskeleton in muscle cells	3/109	233/9376	1.10753238571485	DCN/VIM/ITGB5	0.180261170787798
Organismal Systems	Nervous system	hsa04723	Retrograde endocannabinoid signaling	2/109	149/9376	1.15460870636045	PTGS2/KCNJ5	0.206312777547378
Metabolism	Lipid metabolism	hsa00590	Arachidonic acid metabolism	1/109	63/9376	1.36537061307703	PTGS2	0.315564683316398
Human Diseases	Cancer: specific types	hsa05217	Basal cell carcinoma	1/109	63/9376	1.36537061307703	GADD45B	0.315564683316398
Human Diseases	Cancer: specific types	hsa05226	Gastric cancer	2/109	150/9376	1.14691131498471	HGF/GADD45B	0.196708649213357
Metabolism	Lipid metabolism	hsa00561	Glycerolipid metabolism	1/109	65/9376	1.32335920959774	LPL	0.283708962292685
Organismal Systems	Endocrine system	hsa04927	Cortisol synthesis and secretion	1/109	65/9376	1.32335920959774	NR4A1	0.283708962292685
Metabolism	Lipid metabolism	hsa00140	Steroid hormone biosynthesis	1/109	66/9376	1.30330831248262	CYP19A1	0.268170341908896
Metabolism	Carbohydrate metabolism	hsa00010	Glycolysis / Gluconeogenesis	1/109	67/9376	1.28385594960975	LDHB	0.252879249141781
Cellular Processes	Cell growth and death	hsa04218	Cellular senescence	2/109	157/9376	1.09577514170514	IL1A/GADD45B	0.13124719412709
Cellular Processes	Cell growth and death	hsa04110	Cell cycle	2/109	158/9376	1.08883985599814	ATRX/GADD45B	0.122137026651642
Organismal Systems	Immune system	hsa04664	Fc epsilon RI signaling pathway	1/109	69/9376	1.24664273367903	TNF	0.223006396107136
Human Diseases	Substance dependence	hsa05031	Amphetamine addiction	1/109	69/9376	1.24664273367903	FOSB	0.223006396107136
Organismal Systems	Endocrine system	hsa04920	Adipocytokine signaling pathway	1/109	70/9376	1.22883355176933	TNF	0.208409015951408
Human Diseases	Cancer: specific types	hsa05211	Renal cell carcinoma	1/109	70/9376	1.22883355176933	HGF	0.208409015951408
Human Diseases	Cardiovascular disease	hsa05416	Viral myocarditis	1/109	70/9376	1.22883355176933	HLA-DRB5	0.208409015951408
Organismal Systems	Endocrine system	hsa04917	Prolactin signaling pathway	1/109	71/9376	1.21152603695568	CGA	0.194027873544261
Human Diseases	Cancer: overview	hsa05230	Central carbon metabolism in cancer	1/109	71/9376	1.21152603695568	LDHB	0.194027873544261
Environmental Information Processing	Signal transduction	hsa04020	Calcium signaling pathway	3/109	254/9376	1.01596474752583	CXCR4/HGF/ORAI2	0.0279745548717238
Organismal Systems	Immune system	hsa04622	RIG-I-like receptor signaling pathway	1/109	72/9376	1.19469928644241	TNF	0.179856054836893
Metabolism	Xenobiotics biodegradation and metabolism	hsa00982	Drug metabolism - cytochrome P450	1/109	73/9376	1.17833354279251	MGST1	0.165886965417067
Environmental Information Processing	Signal transduction	hsa04630	JAK-STAT signaling pathway	2/109	168/9376	1.02402795980778	CSH2/CSH1	0.0340814597643016
Cellular Processes	Cell growth and death	hsa04115	p53 signaling pathway	1/109	75/9376	1.14691131498471	GADD45B	0.138532081985
Organismal Systems	Endocrine system	hsa04918	Thyroid hormone synthesis	1/109	75/9376	1.14691131498471	CGA	0.138532081985
Cellular Processes	Transport and catabolism	hsa04140	Autophagy - animal	2/109	169/9376	1.01796862276749	DDIT4/CTSD	0.025563974614375
Human Diseases	Cancer: specific types	hsa05214	Glioma	1/109	76/9376	1.13182037662965	GADD45B	0.125134532566923
Human Diseases	Cancer: specific types	hsa05212	Pancreatic cancer	1/109	77/9376	1.11712141069939	GADD45B	0.11191616995245
Human Diseases	Cancer: specific types	hsa05220	Chronic myeloid leukemia	1/109	77/9376	1.11712141069939	GADD45B	0.11191616995245
Genetic Information Processing	Folding, sorting and degradation	hsa03018	RNA degradation	1/109	78/9376	1.10279934133145	BTG2	0.0988717379293902
Human Diseases	Infectious disease: bacterial	hsa05100	Bacterial invasion of epithelial cells	1/109	78/9376	1.10279934133145	CD2AP	0.0988717379293902
Metabolism	Xenobiotics biodegradation and metabolism	hsa00980	Metabolism of xenobiotics by cytochrome P450	1/109	79/9376	1.08883985599814	MGST1	0.0859962040958149
Metabolism	Xenobiotics biodegradation and metabolism	hsa00983	Drug metabolism - other enzymes	1/109	82/9376	1.0490042515104	MGST1	0.0483357718435527
Organismal Systems	Development and regeneration	hsa04360	Axon guidance	2/109	184/9376	0.934982050259274	CXCR4/NRP1	-0.0965976318986574
Human Diseases	Cardiovascular disease	hsa05412	Arrhythmogenic right ventricular cardiomyopathy	1/109	86/9376	1.00021335609132	ITGB5	0.000215563745374539
Human Diseases	Cancer: specific types	hsa05210	Colorectal cancer	1/109	87/9376	0.988716650848887	GADD45B	-0.011466806334076
Human Diseases	Substance dependence	hsa05032	Morphine addiction	1/109	91/9376	0.945256578284101	KCNJ5	-0.0569103146938548
Human Diseases	Neurodegenerative disease	hsa05022	Pathways of neurodegeneration - multiple diseases	5/109	480/9376	0.896024464831804	IL1B/PTGS2/IL1A/FUS/TNF	-0.253620118780573
Organismal Systems	Immune system	hsa04658	Th1 and Th2 cell differentiation	1/109	93/9376	0.924928479826379	HLA-DRB5	-0.0789045077825599
Organismal Systems	Environmental adaptation	hsa04713	Circadian entrainment	1/109	97/9376	0.886787099214982	KCNJ5	-0.121551550667131
Organismal Systems	Sensory system	hsa04750	Inflammatory mediator regulation of TRP channels	1/109	99/9376	0.86887220832175	IL1B	-0.142245282452355
Human Diseases	Cancer: overview	hsa05203	Viral carcinogenesis	2/109	205/9376	0.839203401208324	C3/CHD4	-0.252449635324485
Human Diseases	Cardiovascular disease	hsa05415	Diabetic cardiomyopathy	2/109	205/9376	0.839203401208324	CTSD/PDK4	-0.252449635324485
Organismal Systems	Digestive system	hsa04974	Protein digestion and absorption	1/109	103/9376	0.835129598289837	SLC16A10	-0.182465383495078
Metabolism	Lipid metabolism	hsa00564	Glycerophospholipid metabolism	1/109	104/9376	0.827099505998589	PLD4	-0.192289468025665
Human Diseases	Cancer: specific types	hsa05215	Prostate cancer	1/109	106/9376	0.811493854942011	PLAU	-0.21167417872844
Organismal Systems	Endocrine system	hsa04922	Glucagon signaling pathway	1/109	107/9376	0.803909800222927	LDHB	-0.22123846796719
Human Diseases	Endocrine and metabolic disease	hsa04931	Insulin resistance	1/109	109/9376	0.789159161686727	TNF	-0.24011965319996
Environmental Information Processing	Signal transduction	hsa04066	HIF-1 signaling pathway	1/109	110/9376	0.781984987489575	LDHB	-0.249439886625485
Metabolism	Global and overview maps	hsa01200	Carbon metabolism	1/109	116/9376	0.741537488136666	SDS	-0.303773837548087
Organismal Systems	Immune system	hsa04670	Leukocyte transendothelial migration	1/109	116/9376	0.741537488136666	CXCR4	-0.303773837548087
Human Diseases	Cancer: overview	hsa05208	Chemical carcinogenesis - reactive oxygen species	2/109	227/9376	0.757870912985491	MGST1/HGF	-0.400499875039441
Genetic Information Processing	Chromosome	hsa03082	ATP-dependent chromatin remodeling	1/109	117/9376	0.735199560887634	CHD4	-0.312578350782928
Environmental Information Processing	Signal transduction	hsa04152	AMPK signaling pathway	1/109	122/9376	0.705068431343059	CAB39	-0.35560326033709
Organismal Systems	Immune system	hsa04660	T cell receptor signaling pathway	1/109	122/9376	0.705068431343059	TNF	-0.35560326033709
Organismal Systems	Endocrine system	hsa04919	Thyroid hormone signaling pathway	1/109	122/9376	0.705068431343059	SLC16A10	-0.35560326033709
Environmental Information Processing	Signal transduction	hsa04068	FoxO signaling pathway	1/109	133/9376	0.646754500931227	GADD45B	-0.444964421023118
Organismal Systems	Immune system	hsa04650	Natural killer cell mediated cytotoxicity	1/109	133/9376	0.646754500931227	TNF	-0.444964421023118
Organismal Systems	Nervous system	hsa04728	Dopaminergic synapse	1/109	133/9376	0.646754500931227	KCNJ5	-0.444964421023118
Cellular Processes	Transport and catabolism	hsa04144	Endocytosis	2/109	250/9376	0.688146788990826	CXCR4/DAB2	-0.54201249435719
Cellular Processes	Cellular community - eukaryotes	hsa04550	Signaling pathways regulating pluripotency of stem cells	1/109	144/9376	0.597349643221203	SKIL	-0.52806908369164
Human Diseases	Cancer: specific types	hsa05224	Breast cancer	1/109	148/9376	0.581205058269278	GADD45B	-0.556939214545536
Metabolism	Global and overview maps	hsa01240	Biosynthesis of cofactors	1/109	154/9376	0.558560705349696	MAT2A	-0.599029342780436
Human Diseases	Endocrine and metabolic disease	hsa04934	Cushing syndrome	1/109	155/9376	0.554957087895827	NR4A1	-0.605909877578291
Human Diseases	Infectious disease: viral	hsa05160	Hepatitis C	1/109	156/9376	0.551399670665726	TNF	-0.612753403777814
Human Diseases	Infectious disease: viral	hsa05161	Hepatitis B	1/109	163/9376	0.527719930207688	TNF	-0.659663099509873
Environmental Information Processing	Signal transduction	hsa04022	cGMP-PKG signaling pathway	1/109	166/9376	0.51818282303526	MEF2C	-0.6792596441839
Genetic Information Processing	Folding, sorting and degradation	hsa04141	Protein processing in endoplasmic reticulum	1/109	174/9376	0.494358325424444	PPP1R15A	-0.730139217895825
Human Diseases	Substance dependence	hsa05034	Alcoholism	1/109	191/9376	0.450357846198184	FOSB	-0.83231254719291
Cellular Processes	Cell motility	hsa04814	Motor proteins	1/109	194/9376	0.443393549607491	MYO5A	-0.84959072269386
Organismal Systems	Immune system	hsa04613	Neutrophil extracellular trap formation	1/109	195/9376	0.441119736532581	C3	-0.855303778589127
Environmental Information Processing	Signal transduction	hsa04015	Rap1 signaling pathway	1/109	212/9376	0.405746927471006	HGF	-0.949130941934997
NA	NA	hsa04382	Cornified envelope formation	1/109	217/9376	0.396397919925591	DST	-0.975631627971269
Human Diseases	Cancer: overview	hsa05207	Chemical carcinogenesis - receptor activation	1/109	217/9376	0.396397919925591	MGST1	-0.975631627971269
Environmental Information Processing	Signal transduction	hsa04024	cAMP signaling pathway	1/109	226/9376	0.380612162052448	CGA	-1.02219947053999
Human Diseases	Neurodegenerative disease	hsa05014	Amyotrophic lateral sclerosis	2/109	368/9376	0.467491025129637	FUS/TNF	-1.13022772877738
Environmental Information Processing	Signal transduction	hsa04014	Ras signaling pathway	1/109	238/9376	0.361421632873333	HGF	-1.08219720851822
Genetic Information Processing	Transcription	hsa03040	Spliceosome	1/109	243/9376	0.353984973760713	FUS	-1.10654309737476
NA	NA	hsa04519	Cadherin signaling	1/109	404/9376	0.212916704514488	VIM	-1.75386455438716