ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0045296 cadherin binding 65/1014 334/18639 0.194610778443114 3.57726853984339 1.31443999752667e-19 1.33678547748462e-16 GO:0003712 transcription coregulator activity 72/1014 495/18639 0.145454545454545 2.673695535234 1.79389356132597e-14 9.12194875934255e-12 GO:0042393 histone binding 46/1014 247/18639 0.186234817813765 3.42330450614474 1.64496120203236e-13 5.57641847488971e-11 GO:0003713 transcription coactivator activity 39/1014 256/18639 0.15234375 2.80033052884615 5.26521914094265e-09 1.33868196658467e-06 GO:0003714 transcription corepressor activity 33/1014 204/18639 0.161764705882353 2.9735033066481 1.77647743786388e-08 3.61335510861513e-06 GO:0140030 modification-dependent protein binding 29/1014 173/18639 0.167630057803468 3.08131819270103 5.80204146776699e-08 8.54438803562819e-06 GO:0003779 actin binding 53/1014 443/18639 0.119638826185102 2.19915984345573 5.88109304320525e-08 8.54438803562819e-06 GO:0048027 mRNA 5'-UTR binding 10/1014 24/18639 0.416666666666667 7.65902366863905 2.11720395391044e-07 2.69149552640865e-05 GO:0140297 DNA-binding transcription factor binding 53/1014 488/18639 0.108606557377049 1.99636846444854 1.26994037825734e-06 0.000143503262743079 GO:0035064 methylated histone binding 16/1014 74/18639 0.216216216216216 3.97441228210459 1.78243946307351e-06 0.000181274093394576 GO:0140034 methylation-dependent protein binding 16/1014 76/18639 0.210526315789474 3.8698224852071 2.59050966249418e-06 0.000239504393341507 GO:0140658 ATP-dependent chromatin remodeler activity 24/1014 158/18639 0.151898734177215 2.79215040071905 4.77734533407005e-06 0.000404880017062437 GO:0003689 DNA clamp loader activity 24/1014 160/18639 0.15 2.75724852071006 5.96653649017589e-06 0.000466766739269914 GO:0008094 ATP-dependent activity, acting on DNA 28/1014 210/18639 0.133333333333333 2.4508875739645 1.05603172521358e-05 0.00075369515625124 GO:0004386 helicase activity 23/1014 155/18639 0.148387096774194 2.72760068715404 1.11164477323192e-05 0.00075369515625124 GO:0070577 lysine-acetylated histone binding 8/1014 23/18639 0.347826086956522 6.39361975816825 1.75791243369904e-05 0.00110590993851599 GO:0000510 H3-H4 histone complex chaperone activity 22/1014 151/18639 0.145695364238411 2.67812218347114 2.29594065657138e-05 0.00110590993851599 GO:0140584 chromatin extrusion motor activity 22/1014 151/18639 0.145695364238411 2.67812218347114 2.29594065657138e-05 0.00110590993851599 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 22/1014 151/18639 0.145695364238411 2.67812218347114 2.29594065657138e-05 0.00110590993851599 GO:0140849 ATP-dependent H2AZ histone chaperone activity 22/1014 151/18639 0.145695364238411 2.67812218347114 2.29594065657138e-05 0.00110590993851599 GO:0140033 acetylation-dependent protein binding 8/1014 24/18639 0.333333333333333 6.12721893491124 2.51148511203497e-05 0.00110590993851599 GO:0015616 DNA translocase activity 22/1014 152/18639 0.144736842105263 2.66050295857988 2.54920561167051e-05 0.00110590993851599 GO:0140674 ATP-dependent histone chaperone activity 22/1014 152/18639 0.144736842105263 2.66050295857988 2.54920561167051e-05 0.00110590993851599 GO:0051015 actin filament binding 27/1014 209/18639 0.129186602870813 2.37466379774072 2.67930290070217e-05 0.00110590993851599 GO:0140713 histone chaperone activity 23/1014 164/18639 0.140243902439024 2.57791528359071 2.82019578258305e-05 0.00110590993851599 GO:0061775 cohesin loader activity 22/1014 153/18639 0.143790849673203 2.64311405035387 2.82730171105365e-05 0.00110590993851599 GO:0140597 protein carrier chaperone 25/1014 188/18639 0.132978723404255 2.44436925594863 3.22798911907481e-05 0.00121587590151818 GO:0042974 nuclear retinoic acid receptor binding 8/1014 25/18639 0.32 5.88213017751479 3.51785843850355e-05 0.00127773643998504 GO:0016922 nuclear receptor binding 20/1014 137/18639 0.145985401459854 2.68345354813631 5.17385946634505e-05 0.00181441899216308 GO:0140104 molecular carrier activity 28/1014 249/18639 0.112449799196787 2.06701361659656 0.000222588596431934 0.00754575341904257 GO:0043021 ribonucleoprotein complex binding 22/1014 177/18639 0.124293785310734 2.28472570454318 0.000253074025472539 0.00830246077114749 GO:0051082 unfolded protein binding 17/1014 121/18639 0.140495867768595 2.58254682380557 0.000294662094789463 0.00936472970002762 GO:0003743 translation initiation factor activity 10/1014 51/18639 0.196078431372549 3.60424643230073 0.000361087453840726 0.011089532415512 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 35/1014 349/18639 0.100286532951289 1.84343263084722 0.000370741496683785 0.011089532415512 GO:0051020 GTPase binding 32/1014 315/18639 0.101587301587302 1.86734291349676 0.000519607293465772 0.0150983033558483 GO:0031490 chromatin DNA binding 17/1014 128/18639 0.1328125 2.4413137943787 0.000574285865701294 0.0162235757060616 GO:0031491 nucleosome binding 12/1014 74/18639 0.162162162162162 2.98080921157844 0.000607740880480068 0.0167046614986008 GO:0044548 S100 protein binding 5/1014 14/18639 0.357142857142857 6.56487743026205 0.000625165678821766 0.0167314077726773 GO:0098632 cell-cell adhesion mediator activity 10/1014 55/18639 0.181818181818182 3.3421194190425 0.0006787712843643 0.0177002665691921 GO:0016887 ATP hydrolysis activity 39/1014 417/18639 0.0935251798561151 1.7191477587161 0.00070754242474211 0.0179892661490681 GO:0098631 cell adhesion mediator activity 12/1014 76/18639 0.157894736842105 2.90236686390533 0.0007776592862108 0.0192897437579606 GO:0031267 small GTPase binding 29/1014 283/18639 0.102473498233216 1.88363267610346 0.000809604247414483 0.0195390549955646 GO:0061749 forked DNA-dependent helicase activity 9/1014 47/18639 0.191489361702128 3.51989172856603 0.000845347512099156 0.0195390549955646 GO:1990518 single-stranded 3'-5' DNA helicase activity 9/1014 47/18639 0.191489361702128 3.51989172856603 0.000845347512099156 0.0195390549955646 GO:0009378 four-way junction helicase activity 9/1014 48/18639 0.1875 3.44656065088757 0.000990968908019809 0.0214428804139606 GO:0036121 double-stranded DNA helicase activity 9/1014 48/18639 0.1875 3.44656065088757 0.000990968908019809 0.0214428804139606 GO:0043138 3'-5' DNA helicase activity 9/1014 48/18639 0.1875 3.44656065088757 0.000990968908019809 0.0214428804139606 GO:0015631 tubulin binding 35/1014 385/18639 0.0909090909090909 1.67105970952125 0.00209533327866668 0.0420085469453403 GO:0008432 JUN kinase binding 4/1014 11/18639 0.363636363636364 6.68423883808499 0.00211134633664066 0.0420085469453403 GO:0048185 activin binding 4/1014 11/18639 0.363636363636364 6.68423883808499 0.00211134633664066 0.0420085469453403 GO:0070990 snRNP binding 4/1014 11/18639 0.363636363636364 6.68423883808499 0.00211134633664066 0.0420085469453403 GO:0019903 protein phosphatase binding 17/1014 144/18639 0.118055555555556 2.1700567061144 0.0021479296373232 0.0420085469453403 GO:0140463 chromatin-protein adaptor activity 9/1014 54/18639 0.166666666666667 3.06360946745562 0.00234766450711499 0.045048581202565 GO:0003724 RNA helicase activity 11/1014 77/18639 0.142857142857143 2.62595097210482 0.00289482739413826 0.0532598985657526 GO:0140097 catalytic activity, acting on DNA 31/1014 336/18639 0.0922619047619048 1.69592666948436 0.0029259601975855 0.0532598985657526 GO:0044389 ubiquitin-like protein ligase binding 30/1014 322/18639 0.093167701863354 1.71257672093793 0.00293269844609847 0.0532598985657526 GO:0046966 nuclear thyroid hormone receptor binding 6/1014 28/18639 0.214285714285714 3.93892645815723 0.00342798087813965 0.0601458262508096 GO:0140938 histone H3 methyltransferase activity 8/1014 47/18639 0.170212765957447 3.12879264761425 0.00353659303193688 0.0601458262508096 GO:0008186 ATP-dependent activity, acting on RNA 11/1014 79/18639 0.139240506329114 2.55947120065913 0.00354842632748139 0.0601458262508096 GO:0046332 SMAD binding 11/1014 79/18639 0.139240506329114 2.55947120065913 0.00354842632748139 0.0601458262508096 GO:0001221 transcription coregulator binding 14/1014 115/18639 0.121739130434783 2.23776691535889 0.00385419881913979 0.06353617753593 GO:0017116 single-stranded DNA helicase activity 9/1014 58/18639 0.155172413793103 2.85232605590696 0.00387339528734283 0.06353617753593 GO:0140666 annealing activity 4/1014 13/18639 0.307692307692308 5.65589440145653 0.00419190733784744 0.0676693613109658 GO:0032452 histone demethylase activity 6/1014 30/18639 0.2 3.67633136094675 0.00492489804015678 0.0782597079193663 GO:0008135 translation factor activity, RNA binding 11/1014 83/18639 0.132530120481928 2.43612319098881 0.00520788733704603 0.0814834064888586 GO:0019888 protein phosphatase regulator activity 13/1014 107/18639 0.121495327102804 2.2332854061826 0.00534073481042834 0.0822958682152366 GO:0180051 translation factor activity 11/1014 84/18639 0.130952380952381 2.40712172442942 0.00570588894453548 0.0855610346399572 GO:0031683 G-protein beta/gamma-subunit complex binding 5/1014 22/18639 0.227272727272727 4.17764927380312 0.00572089513816823 0.0855610346399572 GO:0140457 protein demethylase activity 6/1014 31/18639 0.193548387096774 3.55774002672266 0.00583104142961068 0.0859444802016531 GO:0008201 heparin binding 18/1014 172/18639 0.104651162790698 1.92366175863493 0.00594386782226068 0.0863559082177016 GO:0003678 DNA helicase activity 10/1014 74/18639 0.135135135135135 2.48400767631537 0.00658352042756993 0.0943019757019523 GO:0070717 poly-purine tract binding 6/1014 32/18639 0.1875 3.44656065088757 0.0068529175318786 0.0967974601377852 GO:0003735 structural constituent of ribosome 18/1014 175/18639 0.102857142857143 1.89068469991547 0.00708843835855506 0.0984251790752872 GO:0019838 growth factor binding 15/1014 136/18639 0.110294117647059 2.02738861816916 0.00716171411167281 0.0984251790752872 GO:0004559 alpha-mannosidase activity 4/1014 15/18639 0.266666666666667 4.90177514792899 0.00733593244178927 0.0994752439106625 GO:0004864 protein phosphatase inhibitor activity 8/1014 53/18639 0.150943396226415 2.7745897063749 0.00748622987239361 0.100177576055583 GO:0042826 histone deacetylase binding 14/1014 127/18639 0.110236220472441 2.02632437217537 0.00922428804455293 0.119067528035941 GO:0015035 protein-disulfide reductase activity 6/1014 34/18639 0.176470588235294 3.24382178907066 0.00927533606512846 0.119067528035941 GO:0005159 insulin-like growth factor receptor binding 4/1014 16/18639 0.25 4.59541420118343 0.00936617722996586 0.119067528035941 GO:0015923 mannosidase activity 4/1014 16/18639 0.25 4.59541420118343 0.00936617722996586 0.119067528035941 GO:0050840 extracellular matrix binding 9/1014 67/18639 0.134328358208955 2.46917777974035 0.0100807117758244 0.125085611884287 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 5/1014 25/18639 0.2 3.67633136094675 0.0100855655599917 0.125085611884287 GO:0019212 phosphatase inhibitor activity 8/1014 56/18639 0.142857142857143 2.62595097210482 0.0104036529726908 0.127476085219597 GO:0140566 histone reader activity 6/1014 35/18639 0.171428571428571 3.15114116652578 0.0106912999441518 0.129441095752409 GO:0019208 phosphatase regulator activity 13/1014 117/18639 0.111111111111111 2.04240631163708 0.0111257689536574 0.133116553245524 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 24/1014 268/18639 0.0895522388059701 1.6461185198269 0.0115672458617556 0.134000702909586 GO:0046965 nuclear retinoid X receptor binding 4/1014 17/18639 0.235294117647059 4.32509571876088 0.011729422114358 0.134000702909586 GO:0008143 poly(A) binding 5/1014 26/18639 0.192307692307692 3.53493400091033 0.0119395849277442 0.134000702909586 GO:0004857 enzyme inhibitor activity 34/1014 416/18639 0.0817307692307692 1.50234695038689 0.011969049506672 0.134000702909586 GO:0002039 p53 binding 9/1014 69/18639 0.130434782608696 2.39760740931309 0.0121389262495715 0.134000702909586 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 6/1014 36/18639 0.166666666666667 3.06360946745562 0.0122537515935019 0.134000702909586 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 6/1014 36/18639 0.166666666666667 3.06360946745562 0.0122537515935019 0.134000702909586 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 6/1014 36/18639 0.166666666666667 3.06360946745562 0.0122537515935019 0.134000702909586 GO:0070063 RNA polymerase binding 8/1014 59/18639 0.135593220338983 2.49242804131983 0.0140881139938038 0.149663476012732 GO:0031625 ubiquitin protein ligase binding 26/1014 302/18639 0.0860927152317881 1.5825267447784 0.0141969721230292 0.149663476012732 GO:0015924 mannosyl-oligosaccharide mannosidase activity 3/1014 10/18639 0.3 5.51449704142012 0.0144419741554404 0.149663476012732 GO:0098641 cadherin binding involved in cell-cell adhesion 4/1014 18/18639 0.222222222222222 4.08481262327416 0.0144434353834811 0.149663476012732 GO:0032266 phosphatidylinositol-3-phosphate binding 7/1014 48/18639 0.145833333333333 2.68065828402367 0.0144543714790029 0.149663476012732 GO:0005178 integrin binding 16/1014 161/18639 0.0993788819875776 1.82674850233379 0.0145690109392925 0.149663476012732 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 8/1014 60/18639 0.133333333333333 2.4508875739645 0.0155044432275043 0.15646656046063 GO:0051117 ATPase binding 10/1014 84/18639 0.119047619047619 2.18829247675402 0.0155884887349822 0.15646656046063 GO:0019902 phosphatase binding 18/1014 190/18639 0.0947368421052632 1.7414201183432 0.0157571603418422 0.15646656046063 GO:0042162 telomeric DNA binding 6/1014 38/18639 0.157894736842105 2.90236686390533 0.0158466624655309 0.15646656046063 GO:0008017 microtubule binding 24/1014 276/18639 0.0869565217391304 1.59840493954206 0.0160888950330803 0.157330829313871 GO:0141052 histone H3 demethylase activity 5/1014 28/18639 0.178571428571429 3.28243871513102 0.0163127759779473 0.158000887329261 GO:0001217 DNA-binding transcription repressor activity 24/1014 278/18639 0.0863309352517986 1.58690562343025 0.0174136029725043 0.166556106344735 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 4/1014 19/18639 0.210526315789474 3.8698224852071 0.0175236021424647 0.166556106344735 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 6/1014 39/18639 0.153846153846154 2.82794720072827 0.017890675396238 0.168470526647907 GO:0043022 ribosome binding 12/1014 112/18639 0.107142857142857 1.96946322907861 0.0187257553229536 0.173125722325693 GO:0043236 laminin binding 5/1014 29/18639 0.172413793103448 3.16925117322995 0.0188515765455643 0.173125722325693 GO:0045294 alpha-catenin binding 3/1014 11/18639 0.272727272727273 5.01317912856374 0.0190659595874902 0.173125722325693 GO:0097493 structural molecule activity conferring elasticity 3/1014 11/18639 0.272727272727273 5.01317912856374 0.0190659595874902 0.173125722325693 GO:0015036 disulfide oxidoreductase activity 6/1014 40/18639 0.15 2.75724852071006 0.0201082161040226 0.179386454191149 GO:0032451 demethylase activity 6/1014 40/18639 0.15 2.75724852071006 0.0201082161040226 0.179386454191149 GO:0005201 extracellular matrix structural constituent 16/1014 168/18639 0.0952380952380952 1.75063398140321 0.0209910355567551 0.185633766619304 GO:0001968 fibronectin binding 5/1014 30/18639 0.166666666666667 3.06360946745562 0.0216369122466458 0.189509047286387 GO:0005080 protein kinase C binding 7/1014 52/18639 0.134615384615385 2.47445380063723 0.0218019257940091 0.189509047286387 GO:0003727 single-stranded RNA binding 10/1014 89/18639 0.112359550561798 2.06535469716109 0.022564440977067 0.194474885370145 GO:0005539 glycosaminoglycan binding 21/1014 242/18639 0.0867768595041322 1.59510244999756 0.0237098302299198 0.201835396382983 GO:0005078 MAP-kinase scaffold activity 3/1014 12/18639 0.25 4.59541420118343 0.0244107706539891 0.201835396382983 GO:0035259 nuclear glucocorticoid receptor binding 3/1014 12/18639 0.25 4.59541420118343 0.0244107706539891 0.201835396382983 GO:0070410 co-SMAD binding 3/1014 12/18639 0.25 4.59541420118343 0.0244107706539891 0.201835396382983 GO:1990247 N6-methyladenosine-containing RNA reader activity 3/1014 12/18639 0.25 4.59541420118343 0.0244107706539891 0.201835396382983 GO:0016859 cis-trans isomerase activity 6/1014 42/18639 0.142857142857143 2.62595097210482 0.025087132269845 0.202488996178035 GO:0035198 miRNA binding 6/1014 42/18639 0.142857142857143 2.62595097210482 0.025087132269845 0.202488996178035 GO:0043175 RNA polymerase core enzyme binding 6/1014 42/18639 0.142857142857143 2.62595097210482 0.025087132269845 0.202488996178035 GO:0019199 transmembrane receptor protein kinase activity 9/1014 78/18639 0.115384615384615 2.1209604005462 0.0254166848642973 0.203533610291263 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 7/1014 54/18639 0.12962962962963 2.38280736357659 0.0263038811523233 0.208992555718069 GO:0042054 histone methyltransferase activity 8/1014 67/18639 0.119402985074627 2.19482469310254 0.0284191070863478 0.22404830935516 GO:0140517 protein-RNA adaptor activity 4/1014 22/18639 0.181818181818182 3.3421194190425 0.029078775291719 0.227196580843934 GO:0008013 beta-catenin binding 11/1014 106/18639 0.10377358490566 1.90753042313275 0.0292652429602314 0.227196580843934 GO:0046974 histone H3K9 methyltransferase activity 3/1014 13/18639 0.230769230769231 4.2419208010924 0.0304764296488315 0.231302454872102 GO:0051011 microtubule minus-end binding 3/1014 13/18639 0.230769230769231 4.2419208010924 0.0304764296488315 0.231302454872102 GO:0086080 protein binding involved in heterotypic cell-cell adhesion 3/1014 13/18639 0.230769230769231 4.2419208010924 0.0304764296488315 0.231302454872102 GO:0051087 protein-folding chaperone binding 13/1014 134/18639 0.0970149253731343 1.78329506314581 0.0308189697991871 0.23216957248721 GO:0030246 carbohydrate binding 23/1014 280/18639 0.0821428571428571 1.50992180896027 0.0324836251903744 0.242910638372138 GO:0016279 protein-lysine N-methyltransferase activity 8/1014 69/18639 0.115942028985507 2.13120658605608 0.0331701873893525 0.246234164780814 GO:0017134 fibroblast growth factor binding 4/1014 23/18639 0.173913043478261 3.19680987908413 0.0337294448366857 0.248571343470358 GO:0016504 peptidase activator activity 7/1014 57/18639 0.12280701754386 2.25739644970414 0.0341811165210585 0.25008773742386 GO:0016278 lysine N-methyltransferase activity 8/1014 70/18639 0.114285714285714 2.10076077768385 0.035736887552009 0.259602961717094 GO:0061980 regulatory RNA binding 7/1014 58/18639 0.120689655172414 2.21847582126097 0.0371201213395379 0.26495934172385 GO:0008494 translation activator activity 3/1014 14/18639 0.214285714285714 3.93892645815723 0.0372558366435698 0.26495934172385 GO:0032454 histone H3K9 demethylase activity 3/1014 14/18639 0.214285714285714 3.93892645815723 0.0372558366435698 0.26495934172385 GO:0035035 histone acetyltransferase binding 4/1014 24/18639 0.166666666666667 3.06360946745562 0.0387875476090314 0.272047833919896 GO:0070840 dynein complex binding 4/1014 24/18639 0.166666666666667 3.06360946745562 0.0387875476090314 0.272047833919896 GO:0001098 basal transcription machinery binding 7/1014 60/18639 0.116666666666667 2.14452662721893 0.0434849798003466 0.296636672231198 GO:0001099 basal RNA polymerase II transcription machinery binding 7/1014 60/18639 0.116666666666667 2.14452662721893 0.0434849798003466 0.296636672231198 GO:0000993 RNA polymerase II complex binding 5/1014 36/18639 0.138888888888889 2.55300788954635 0.0438944090228116 0.296636672231198 GO:0140693 molecular condensate scaffold activity 6/1014 48/18639 0.125 2.29770710059172 0.0447165681215655 0.296636672231198 GO:0005523 tropomyosin binding 3/1014 15/18639 0.2 3.67633136094675 0.044735812694015 0.296636672231198 GO:0042809 nuclear vitamin D receptor binding 3/1014 15/18639 0.2 3.67633136094675 0.044735812694015 0.296636672231198 GO:0061578 K63-linked deubiquitinase activity 3/1014 15/18639 0.2 3.67633136094675 0.044735812694015 0.296636672231198 GO:1901681 sulfur compound binding 22/1014 275/18639 0.08 1.4705325443787 0.0458013101123864 0.296636672231198 GO:0019905 syntaxin binding 7/1014 61/18639 0.114754098360656 2.10937045300223 0.0469154936626781 0.296636672231198 GO:0017124 SH3 domain binding 11/1014 115/18639 0.0956521739130435 1.75824543349627 0.0485590559965596 0.296636672231198 GO:0043394 proteoglycan binding 5/1014 37/18639 0.135135135135135 2.48400767631537 0.0485701142754194 0.296636672231198 GO:0005004 GPI-linked ephrin receptor activity 6/1014 49/18639 0.122448979591837 2.25081511894699 0.0487102500123992 0.296636672231198 GO:0005008 hepatocyte growth factor receptor activity 6/1014 49/18639 0.122448979591837 2.25081511894699 0.0487102500123992 0.296636672231198 GO:0005009 insulin receptor activity 6/1014 49/18639 0.122448979591837 2.25081511894699 0.0487102500123992 0.296636672231198 GO:0005011 macrophage colony-stimulating factor receptor activity 6/1014 49/18639 0.122448979591837 2.25081511894699 0.0487102500123992 0.296636672231198 GO:0005018 platelet-derived growth factor alpha-receptor activity 6/1014 49/18639 0.122448979591837 2.25081511894699 0.0487102500123992 0.296636672231198 GO:0005020 stem cell factor receptor activity 6/1014 49/18639 0.122448979591837 2.25081511894699 0.0487102500123992 0.296636672231198 GO:0008288 boss receptor activity 6/1014 49/18639 0.122448979591837 2.25081511894699 0.0487102500123992 0.296636672231198 GO:0036332 placental growth factor receptor activity 6/1014 49/18639 0.122448979591837 2.25081511894699 0.0487102500123992 0.296636672231198 GO:0038062 protein tyrosine kinase collagen receptor activity 6/1014 49/18639 0.122448979591837 2.25081511894699 0.0487102500123992 0.296636672231198 GO:0060175 brain-derived neurotrophic factor receptor activity 6/1014 49/18639 0.122448979591837 2.25081511894699 0.0487102500123992 0.296636672231198 GO:0060590 ATPase regulator activity 6/1014 49/18639 0.122448979591837 2.25081511894699 0.0487102500123992 0.296636672231198 GO:0004197 cysteine-type endopeptidase activity 9/1014 88/18639 0.102272727272727 1.8799421732114 0.0495982004086687 0.298141862074298 GO:0008157 protein phosphatase 1 binding 4/1014 26/18639 0.153846153846154 2.82794720072827 0.0501300476054129 0.298141862074298 GO:0050681 nuclear androgen receptor binding 4/1014 26/18639 0.153846153846154 2.82794720072827 0.0501300476054129 0.298141862074298 GO:0070006 metalloaminopeptidase activity 4/1014 26/18639 0.153846153846154 2.82794720072827 0.0501300476054129 0.298141862074298 GO:0044183 protein folding chaperone 8/1014 75/18639 0.106666666666667 1.9607100591716 0.0505722105435087 0.298978809336443 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 3/1014 16/18639 0.1875 3.44656065088757 0.0528980362626417 0.298978809336443 GO:0005024 transforming growth factor beta receptor activity 3/1014 16/18639 0.1875 3.44656065088757 0.0528980362626417 0.298978809336443 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 3/1014 16/18639 0.1875 3.44656065088757 0.0528980362626417 0.298978809336443 GO:0055102 lipase inhibitor activity 3/1014 16/18639 0.1875 3.44656065088757 0.0528980362626417 0.298978809336443 GO:0005006 epidermal growth factor receptor activity 6/1014 50/18639 0.12 2.20579881656805 0.0529166034223793 0.298978809336443 GO:0005007 fibroblast growth factor receptor activity 6/1014 50/18639 0.12 2.20579881656805 0.0529166034223793 0.298978809336443 GO:0005017 platelet-derived growth factor receptor activity 6/1014 50/18639 0.12 2.20579881656805 0.0529166034223793 0.298978809336443 GO:0005019 platelet-derived growth factor beta-receptor activity 6/1014 50/18639 0.12 2.20579881656805 0.0529166034223793 0.298978809336443 GO:0008266 poly(U) RNA binding 4/1014 27/18639 0.148148148148148 2.72320841551611 0.0564114611524196 0.316910983419921 GO:0005010 insulin-like growth factor receptor activity 6/1014 51/18639 0.117647058823529 2.16254785938044 0.0573368937554233 0.316910983419921 GO:0005021 vascular endothelial growth factor receptor activity 6/1014 51/18639 0.117647058823529 2.16254785938044 0.0573368937554233 0.316910983419921 GO:0005030 neurotrophin receptor activity 6/1014 51/18639 0.117647058823529 2.16254785938044 0.0573368937554233 0.316910983419921 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 3/1014 17/18639 0.176470588235294 3.24382178907066 0.0617198821515596 0.328634136901236 GO:0016018 cyclosporin A binding 3/1014 17/18639 0.176470588235294 3.24382178907066 0.0617198821515596 0.328634136901236 GO:0019198 transmembrane receptor protein phosphatase activity 3/1014 17/18639 0.176470588235294 3.24382178907066 0.0617198821515596 0.328634136901236 GO:0032183 SUMO binding 3/1014 17/18639 0.176470588235294 3.24382178907066 0.0617198821515596 0.328634136901236 GO:0051787 misfolded protein binding 3/1014 17/18639 0.176470588235294 3.24382178907066 0.0617198821515596 0.328634136901236 GO:0070492 oligosaccharide binding 3/1014 17/18639 0.176470588235294 3.24382178907066 0.0617198821515596 0.328634136901236 GO:1990226 histone methyltransferase binding 3/1014 17/18639 0.176470588235294 3.24382178907066 0.0617198821515596 0.328634136901236 GO:0038024 cargo receptor activity 7/1014 65/18639 0.107692307692308 1.97956304050979 0.0623319398187957 0.330164493727684 GO:0030331 nuclear estrogen receptor binding 5/1014 40/18639 0.125 2.29770710059172 0.0642920004343515 0.338782199179976 GO:0051213 dioxygenase activity 9/1014 93/18639 0.0967741935483871 1.77887001336133 0.0660079898917334 0.344880964481003 GO:0005003 ephrin receptor activity 6/1014 53/18639 0.113207547169811 2.08094227978118 0.0668218668083243 0.344880964481003 GO:0005005 transmembrane-ephrin receptor activity 6/1014 53/18639 0.113207547169811 2.08094227978118 0.0668218668083243 0.344880964481003 GO:0038064 collagen receptor activity 6/1014 53/18639 0.113207547169811 2.08094227978118 0.0668218668083243 0.344880964481003 GO:0044325 transmembrane transporter binding 12/1014 136/18639 0.0882352941176471 1.62191089453533 0.0671449665361245 0.344880964481003 GO:0048306 calcium-dependent protein binding 8/1014 80/18639 0.1 1.83816568047337 0.0688949447625398 0.352091250369361 GO:0106222 lncRNA binding 4/1014 29/18639 0.137931034482759 2.53540093858396 0.070173455156581 0.356832019471214 GO:0016500 protein-hormone receptor activity 7/1014 67/18639 0.104477611940299 1.92047160646472 0.0710715072220184 0.358342323865165 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 3/1014 18/18639 0.166666666666667 3.06360946745562 0.0711751715051753 0.358342323865165 GO:0008276 protein methyltransferase activity 9/1014 95/18639 0.0947368421052632 1.7414201183432 0.0734256747060383 0.36785177919232 GO:0008307 structural constituent of muscle 5/1014 42/18639 0.119047619047619 2.18829247675402 0.0761779652209685 0.377598858537404 GO:0031492 nucleosomal DNA binding 5/1014 42/18639 0.119047619047619 2.18829247675402 0.0761779652209685 0.377598858537404 GO:0004222 metalloendopeptidase activity 10/1014 110/18639 0.0909090909090909 1.67105970952125 0.0764851178551674 0.377598858537404 GO:0008187 poly-pyrimidine tract binding 4/1014 30/18639 0.133333333333333 2.4508875739645 0.0776406156042633 0.381451720142685 GO:0008574 plus-end-directed microtubule motor activity 3/1014 19/18639 0.157894736842105 2.90236686390533 0.0812348407606836 0.3896973257246 GO:0042800 histone H3K4 methyltransferase activity 3/1014 19/18639 0.157894736842105 2.90236686390533 0.0812348407606836 0.3896973257246 GO:0043395 heparan sulfate proteoglycan binding 3/1014 19/18639 0.157894736842105 2.90236686390533 0.0812348407606836 0.3896973257246 GO:0046527 glucosyltransferase activity 3/1014 19/18639 0.157894736842105 2.90236686390533 0.0812348407606836 0.3896973257246 GO:1990380 K48-linked deubiquitinase activity 3/1014 19/18639 0.157894736842105 2.90236686390533 0.0812348407606836 0.3896973257246 GO:0097110 scaffold protein binding 7/1014 70/18639 0.1 1.83816568047337 0.0854764384256001 0.408119896144767 GO:0030020 extracellular matrix structural constituent conferring tensile strength 5/1014 44/18639 0.113636363636364 2.08882463690156 0.0891651814362545 0.423742941685378 GO:0000339 RNA cap binding 3/1014 20/18639 0.15 2.75724852071006 0.0918675367943118 0.428574701467042 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 3/1014 20/18639 0.15 2.75724852071006 0.0918675367943118 0.428574701467042 GO:0031418 L-ascorbic acid binding 3/1014 20/18639 0.15 2.75724852071006 0.0918675367943118 0.428574701467042 GO:0043024 ribosomal small subunit binding 3/1014 20/18639 0.15 2.75724852071006 0.0918675367943118 0.428574701467042 GO:0051059 NF-kappaB binding 4/1014 32/18639 0.125 2.29770710059172 0.0937028628521702 0.435140691875147 GO:0035401 histone H3Y41 kinase activity 10/1014 115/18639 0.0869565217391304 1.59840493954206 0.0960528918969866 0.436436665193392 GO:0140801 histone H2AXY142 kinase activity 10/1014 115/18639 0.0869565217391304 1.59840493954206 0.0960528918969866 0.436436665193392 GO:0001094 TFIID-class transcription factor complex binding 2/1014 10/18639 0.2 3.67633136094675 0.0995607731807935 0.436436665193392 GO:0005522 profilin binding 2/1014 10/18639 0.2 3.67633136094675 0.0995607731807935 0.436436665193392 GO:0035374 chondroitin sulfate binding 2/1014 10/18639 0.2 3.67633136094675 0.0995607731807935 0.436436665193392 GO:0042975 peroxisome proliferator activated receptor binding 2/1014 10/18639 0.2 3.67633136094675 0.0995607731807935 0.436436665193392 GO:0045322 unmethylated CpG binding 2/1014 10/18639 0.2 3.67633136094675 0.0995607731807935 0.436436665193392 GO:0050815 phosphoserine residue binding 2/1014 10/18639 0.2 3.67633136094675 0.0995607731807935 0.436436665193392 GO:0051880 G-quadruplex DNA binding 2/1014 10/18639 0.2 3.67633136094675 0.0995607731807935 0.436436665193392 GO:0099122 RNA polymerase II C-terminal domain binding 2/1014 10/18639 0.2 3.67633136094675 0.0995607731807935 0.436436665193392 GO:0140940 histone H2A methyltransferase activity 2/1014 10/18639 0.2 3.67633136094675 0.0995607731807935 0.436436665193392 GO:0140999 histone H3K4 trimethyltransferase activity 2/1014 10/18639 0.2 3.67633136094675 0.0995607731807935 0.436436665193392 GO:1990259 histone H2AQ104 methyltransferase activity 2/1014 10/18639 0.2 3.67633136094675 0.0995607731807935 0.436436665193392 GO:0031072 heat shock protein binding 11/1014 131/18639 0.083969465648855 1.54349789963413 0.100960396198994 0.440301795764554 GO:0140416 transcription regulator inhibitor activity 4/1014 33/18639 0.121212121212121 2.228079612695 0.102276388757355 0.440301795764554 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 3/1014 21/18639 0.142857142857143 2.62595097210482 0.103040144928185 0.440301795764554 GO:0010314 phosphatidylinositol-5-phosphate binding 3/1014 21/18639 0.142857142857143 2.62595097210482 0.103040144928185 0.440301795764554 GO:0035613 RNA stem-loop binding 3/1014 21/18639 0.142857142857143 2.62595097210482 0.103040144928185 0.440301795764554 GO:0036122 BMP binding 3/1014 21/18639 0.142857142857143 2.62595097210482 0.103040144928185 0.440301795764554 GO:0004674 protein serine/threonine kinase activity 30/1014 433/18639 0.069284064665127 1.27355589871134 0.104055988887346 0.442782178654523 GO:0004714 transmembrane receptor protein tyrosine kinase activity 6/1014 60/18639 0.1 1.83816568047337 0.106714659411713 0.449041857883284 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 33/1014 484/18639 0.0681818181818182 1.25329478214094 0.107605381180489 0.449041857883284 GO:0008376 acetylgalactosaminyltransferase activity 4/1014 34/18639 0.117647058823529 2.16254785938044 0.111195325552495 0.449041857883284 GO:0003725 double-stranded RNA binding 7/1014 75/18639 0.0933333333333333 1.71562130177515 0.112888478533872 0.449041857883284 GO:0032931 histone H3K56 acetyltransferase activity 3/1014 22/18639 0.136363636363636 2.50658956428187 0.114718255923416 0.449041857883284 GO:0043992 histone H3K9 acetyltransferase activity 3/1014 22/18639 0.136363636363636 2.50658956428187 0.114718255923416 0.449041857883284 GO:0043993 histone H3K18 acetyltransferase activity 3/1014 22/18639 0.136363636363636 2.50658956428187 0.114718255923416 0.449041857883284 GO:0043994 histone H3K23 acetyltransferase activity 3/1014 22/18639 0.136363636363636 2.50658956428187 0.114718255923416 0.449041857883284 GO:0043999 histone H2AK5 acetyltransferase activity 3/1014 22/18639 0.136363636363636 2.50658956428187 0.114718255923416 0.449041857883284 GO:0044012 histone H2AK9 acetyltransferase activity 3/1014 22/18639 0.136363636363636 2.50658956428187 0.114718255923416 0.449041857883284 GO:0044014 histone H2BK5 acetyltransferase activity 3/1014 22/18639 0.136363636363636 2.50658956428187 0.114718255923416 0.449041857883284 GO:0044015 histone H2BK12 acetyltransferase activity 3/1014 22/18639 0.136363636363636 2.50658956428187 0.114718255923416 0.449041857883284 GO:0044016 histone H3K4 acetyltransferase activity 3/1014 22/18639 0.136363636363636 2.50658956428187 0.114718255923416 0.449041857883284 GO:0044017 histone H3K27 acetyltransferase activity 3/1014 22/18639 0.136363636363636 2.50658956428187 0.114718255923416 0.449041857883284 GO:0044018 histone H3K36 acetyltransferase activity 3/1014 22/18639 0.136363636363636 2.50658956428187 0.114718255923416 0.449041857883284 GO:0046972 histone H4K16 acetyltransferase activity 3/1014 22/18639 0.136363636363636 2.50658956428187 0.114718255923416 0.449041857883284 GO:0061133 endopeptidase activator activity 3/1014 22/18639 0.136363636363636 2.50658956428187 0.114718255923416 0.449041857883284 GO:0140908 histone H3K122 acetyltransferase activity 3/1014 22/18639 0.136363636363636 2.50658956428187 0.114718255923416 0.449041857883284 GO:0002162 dystroglycan binding 2/1014 11/18639 0.181818181818182 3.3421194190425 0.117448509534861 0.449041857883284 GO:0005114 type II transforming growth factor beta receptor binding 2/1014 11/18639 0.181818181818182 3.3421194190425 0.117448509534861 0.449041857883284 GO:0005225 volume-sensitive anion channel activity 2/1014 11/18639 0.181818181818182 3.3421194190425 0.117448509534861 0.449041857883284 GO:0008046 axon guidance receptor activity 2/1014 11/18639 0.181818181818182 3.3421194190425 0.117448509534861 0.449041857883284 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity 2/1014 11/18639 0.181818181818182 3.3421194190425 0.117448509534861 0.449041857883284 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 2/1014 11/18639 0.181818181818182 3.3421194190425 0.117448509534861 0.449041857883284 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives 2/1014 11/18639 0.181818181818182 3.3421194190425 0.117448509534861 0.449041857883284 GO:0019107 myristoyltransferase activity 2/1014 11/18639 0.181818181818182 3.3421194190425 0.117448509534861 0.449041857883284 GO:0043522 leucine zipper domain binding 2/1014 11/18639 0.181818181818182 3.3421194190425 0.117448509534861 0.449041857883284 GO:0032182 ubiquitin-like protein binding 10/1014 120/18639 0.0833333333333333 1.53180473372781 0.118310218281364 0.450642292105421 GO:0061631 ubiquitin conjugating enzyme activity 4/1014 35/18639 0.114285714285714 2.10076077768385 0.120446351653625 0.45706693892439 GO:0002020 protease binding 11/1014 136/18639 0.0808823529411765 1.48675165332405 0.122337548654341 0.462324478535972 GO:0000149 SNARE binding 9/1014 106/18639 0.0849056603773585 1.56070670983588 0.123024719197833 0.462324478535972 GO:0001216 DNA-binding transcription activator activity 33/1014 491/18639 0.0672097759674134 1.23542703575603 0.123195608341444 0.462324478535972 GO:0004602 glutathione peroxidase activity 3/1014 23/18639 0.130434782608696 2.39760740931309 0.126866577586426 0.472612854964817 GO:0044013 histone H2B acetyltransferase activity 3/1014 23/18639 0.130434782608696 2.39760740931309 0.126866577586426 0.472612854964817 GO:0008237 metallopeptidase activity 14/1014 184/18639 0.0760869565217391 1.39860432209931 0.129010131640122 0.478844174737242 GO:0051219 phosphoprotein binding 8/1014 93/18639 0.0860215053763441 1.58121778965451 0.133245965742721 0.485505299246747 GO:0004843 cysteine-type deubiquitinase activity 9/1014 108/18639 0.0833333333333333 1.53180473372781 0.133607356641165 0.485505299246747 GO:0004859 phospholipase inhibitor activity 2/1014 12/18639 0.166666666666667 3.06360946745562 0.136056057311035 0.485505299246747 GO:0016273 arginine N-methyltransferase activity 2/1014 12/18639 0.166666666666667 3.06360946745562 0.136056057311035 0.485505299246747 GO:0016274 protein-arginine N-methyltransferase activity 2/1014 12/18639 0.166666666666667 3.06360946745562 0.136056057311035 0.485505299246747 GO:0016423 tRNA (guanine) methyltransferase activity 2/1014 12/18639 0.166666666666667 3.06360946745562 0.136056057311035 0.485505299246747 GO:0017166 vinculin binding 2/1014 12/18639 0.166666666666667 3.06360946745562 0.136056057311035 0.485505299246747 GO:0035197 siRNA binding 2/1014 12/18639 0.166666666666667 3.06360946745562 0.136056057311035 0.485505299246747 GO:0035251 UDP-glucosyltransferase activity 2/1014 12/18639 0.166666666666667 3.06360946745562 0.136056057311035 0.485505299246747 GO:0035497 cAMP response element binding 2/1014 12/18639 0.166666666666667 3.06360946745562 0.136056057311035 0.485505299246747 GO:0036009 protein-glutamine N-methyltransferase activity 2/1014 12/18639 0.166666666666667 3.06360946745562 0.136056057311035 0.485505299246747 GO:0030215 semaphorin receptor binding 3/1014 24/18639 0.125 2.29770710059172 0.139449296154625 0.490570968929855 GO:0043998 histone H2A acetyltransferase activity 3/1014 24/18639 0.125 2.29770710059172 0.139449296154625 0.490570968929855 GO:0050431 transforming growth factor beta binding 3/1014 24/18639 0.125 2.29770710059172 0.139449296154625 0.490570968929855 GO:0070300 phosphatidic acid binding 3/1014 24/18639 0.125 2.29770710059172 0.139449296154625 0.490570968929855 GO:0042805 actinin binding 4/1014 37/18639 0.108108108108108 1.98720614105229 0.139887493598484 0.490570968929855 GO:0019843 rRNA binding 6/1014 65/18639 0.0923076923076923 1.69676832043696 0.141259397924696 0.492011133860494 GO:0008234 cysteine-type peptidase activity 14/1014 187/18639 0.0748663101604278 1.37616681960573 0.141265733615796 0.492011133860494 GO:0005048 signal sequence binding 5/1014 51/18639 0.0980392156862745 1.80212321615037 0.142723714688775 0.493707543668314 GO:0030544 Hsp70 protein binding 5/1014 51/18639 0.0980392156862745 1.80212321615037 0.142723714688775 0.493707543668314 GO:0008235 metalloexopeptidase activity 6/1014 66/18639 0.0909090909090909 1.67105970952125 0.148723809085934 0.512719029967439 GO:0019783 ubiquitin-like protein peptidase activity 10/1014 127/18639 0.078740157480315 1.44737455155384 0.153833865577637 0.517677518868398 GO:0005338 nucleotide-sugar transmembrane transporter activity 2/1014 13/18639 0.153846153846154 2.82794720072827 0.155252353249618 0.517677518868398 GO:0031994 insulin-like growth factor I binding 2/1014 13/18639 0.153846153846154 2.82794720072827 0.155252353249618 0.517677518868398 GO:0043560 insulin receptor substrate binding 2/1014 13/18639 0.153846153846154 2.82794720072827 0.155252353249618 0.517677518868398 GO:0045159 myosin II binding 2/1014 13/18639 0.153846153846154 2.82794720072827 0.155252353249618 0.517677518868398 GO:0046975 histone H3K36 methyltransferase activity 2/1014 13/18639 0.153846153846154 2.82794720072827 0.155252353249618 0.517677518868398 GO:0070123 transforming growth factor beta receptor activity, type III 2/1014 13/18639 0.153846153846154 2.82794720072827 0.155252353249618 0.517677518868398 GO:0071837 HMG box domain binding 2/1014 13/18639 0.153846153846154 2.82794720072827 0.155252353249618 0.517677518868398 GO:0089720 caspase binding 2/1014 13/18639 0.153846153846154 2.82794720072827 0.155252353249618 0.517677518868398 GO:0140410 monoatomic cation:bicarbonate symporter activity 2/1014 13/18639 0.153846153846154 2.82794720072827 0.155252353249618 0.517677518868398 GO:0019887 protein kinase regulator activity 18/1014 255/18639 0.0705882352941176 1.29752871562826 0.15619910141333 0.519132307638422 GO:0141003 histone H2AX kinase activity 24/1014 354/18639 0.0677966101694915 1.24621402065991 0.157448839878077 0.521581336013043 GO:0004721 phosphoprotein phosphatase activity 13/1014 175/18639 0.0742857142857143 1.36549450549451 0.158325562091882 0.52278278132287 GO:0005544 calcium-dependent phospholipid binding 5/1014 53/18639 0.0943396226415094 1.73411856648431 0.160115633087119 0.525282576934195 GO:1901505 carbohydrate derivative transmembrane transporter activity 5/1014 53/18639 0.0943396226415094 1.73411856648431 0.160115633087119 0.525282576934195 GO:0030695 GTPase regulator activity 32/1014 489/18639 0.065439672801636 1.20288960685374 0.160783384046885 0.52577717548451 GO:0060589 nucleoside-triphosphatase regulator activity 32/1014 490/18639 0.0653061224489796 1.20043473010506 0.163570972412409 0.530026990069293 GO:0004725 protein tyrosine phosphatase activity 8/1014 98/18639 0.0816326530612245 1.50054341263132 0.164090520359584 0.530026990069293 GO:0008170 N-methyltransferase activity 8/1014 98/18639 0.0816326530612245 1.50054341263132 0.164090520359584 0.530026990069293 GO:1990841 promoter-specific chromatin binding 6/1014 68/18639 0.0882352941176471 1.62191089453533 0.164167651791374 0.530026990069293 GO:0035591 signaling adaptor activity 10/1014 129/18639 0.0775193798449612 1.42493463602587 0.164870123219966 0.530163748339521 GO:0050750 low-density lipoprotein particle receptor binding 3/1014 26/18639 0.115384615384615 2.1209604005462 0.165773915409998 0.530163748339521 GO:0070412 R-SMAD binding 3/1014 26/18639 0.115384615384615 2.1209604005462 0.165773915409998 0.530163748339521 GO:0140996 histone H3 kinase activity 24/1014 357/18639 0.0672268907563025 1.23574163393168 0.167291548351907 0.533340140043541 GO:0017069 snRNA binding 5/1014 54/18639 0.0925925925925926 1.70200525969757 0.169118594114854 0.53748003192127 GO:0061134 peptidase regulator activity 16/1014 226/18639 0.0707964601769911 1.30135623396345 0.170455661587769 0.538936616301332 GO:0004177 aminopeptidase activity 4/1014 40/18639 0.1 1.83816568047337 0.171166693279578 0.538936616301332 GO:0140662 ATP-dependent protein folding chaperone 4/1014 40/18639 0.1 1.83816568047337 0.171166693279578 0.538936616301332 GO:0004860 protein kinase inhibitor activity 7/1014 84/18639 0.0833333333333333 1.53180473372781 0.172214234326844 0.540561346637038 GO:0101005 deubiquitinase activity 9/1014 115/18639 0.0782608695652174 1.43856444558786 0.174161594138184 0.544012393943689 GO:0043176 amine binding 2/1014 14/18639 0.142857142857143 2.62595097210482 0.174918439350626 0.544012393943689 GO:0070742 C2H2 zinc finger domain binding 2/1014 14/18639 0.142857142857143 2.62595097210482 0.174918439350626 0.544012393943689 GO:0035173 histone kinase activity 24/1014 360/18639 0.0666666666666667 1.22544378698225 0.177462077474075 0.549683054124886 GO:0001671 ATPase activator activity 3/1014 27/18639 0.111111111111111 2.04240631163708 0.179444222192195 0.549683054124886 GO:0005044 scavenger receptor activity 3/1014 27/18639 0.111111111111111 2.04240631163708 0.179444222192195 0.549683054124886 GO:0008320 protein transmembrane transporter activity 3/1014 27/18639 0.111111111111111 2.04240631163708 0.179444222192195 0.549683054124886 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 3/1014 27/18639 0.111111111111111 2.04240631163708 0.179444222192195 0.549683054124886 GO:0042169 SH2 domain binding 4/1014 41/18639 0.0975609756097561 1.79333237119353 0.18209328463921 0.554457696042146 GO:0061650 ubiquitin-like protein conjugating enzyme activity 4/1014 41/18639 0.0975609756097561 1.79333237119353 0.18209328463921 0.554457696042146 GO:1990782 protein tyrosine kinase binding 9/1014 117/18639 0.0769230769230769 1.41397360036413 0.186686652041693 0.56674723918329 GO:0005085 guanyl-nucleotide exchange factor activity 16/1014 230/18639 0.0695652173913043 1.27872395163365 0.187968637556375 0.568940786889384 GO:0048487 beta-tubulin binding 4/1014 42/18639 0.0952380952380952 1.75063398140321 0.193242265630604 0.571356273392633 GO:0036408 histone H3K14 acetyltransferase activity 3/1014 28/18639 0.107142857142857 1.96946322907861 0.193406179813478 0.571356273392633 GO:0045499 chemorepellent activity 3/1014 28/18639 0.107142857142857 1.96946322907861 0.193406179813478 0.571356273392633 GO:0051393 alpha-actinin binding 3/1014 28/18639 0.107142857142857 1.96946322907861 0.193406179813478 0.571356273392633 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 3/1014 28/18639 0.107142857142857 1.96946322907861 0.193406179813478 0.571356273392633 GO:0000774 adenyl-nucleotide exchange factor activity 2/1014 15/18639 0.133333333333333 2.4508875739645 0.194946535759335 0.571356273392633 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 2/1014 15/18639 0.133333333333333 2.4508875739645 0.194946535759335 0.571356273392633 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 2/1014 15/18639 0.133333333333333 2.4508875739645 0.194946535759335 0.571356273392633 GO:0031005 filamin binding 2/1014 15/18639 0.133333333333333 2.4508875739645 0.194946535759335 0.571356273392633 GO:0045504 dynein heavy chain binding 2/1014 15/18639 0.133333333333333 2.4508875739645 0.194946535759335 0.571356273392633 GO:0051371 muscle alpha-actinin binding 2/1014 15/18639 0.133333333333333 2.4508875739645 0.194946535759335 0.571356273392633 GO:0005518 collagen binding 6/1014 72/18639 0.0833333333333333 1.53180473372781 0.196952327730585 0.575576199143691 GO:0004629 phospholipase C activity 3/1014 29/18639 0.103448275862069 1.90155070393797 0.207625340350813 0.600497137367914 GO:0010484 histone H3 acetyltransferase activity 3/1014 29/18639 0.103448275862069 1.90155070393797 0.207625340350813 0.600497137367914 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 3/1014 29/18639 0.103448275862069 1.90155070393797 0.207625340350813 0.600497137367914 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 7/1014 89/18639 0.0786516853932584 1.44574828801277 0.209978629403864 0.600497137367914 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 7/1014 89/18639 0.0786516853932584 1.44574828801277 0.209978629403864 0.600497137367914 GO:0003774 cytoskeletal motor activity 11/1014 153/18639 0.0718954248366013 1.32155702517693 0.211606599359151 0.600497137367914 GO:0003697 single-stranded DNA binding 9/1014 121/18639 0.0743801652892562 1.36723067142648 0.2128628911158 0.600497137367914 GO:0048029 monosaccharide binding 6/1014 74/18639 0.0810810810810811 1.49040460578922 0.214192804191909 0.600497137367914 GO:0000062 fatty-acyl-CoA binding 2/1014 16/18639 0.125 2.29770710059172 0.215239178544577 0.600497137367914 GO:0005324 long-chain fatty acid transmembrane transporter activity 2/1014 16/18639 0.125 2.29770710059172 0.215239178544577 0.600497137367914 GO:0017070 U6 snRNA binding 2/1014 16/18639 0.125 2.29770710059172 0.215239178544577 0.600497137367914 GO:0030275 LRR domain binding 2/1014 16/18639 0.125 2.29770710059172 0.215239178544577 0.600497137367914 GO:0034450 ubiquitin-ubiquitin ligase activity 2/1014 16/18639 0.125 2.29770710059172 0.215239178544577 0.600497137367914 GO:0140328 floppase activity 2/1014 16/18639 0.125 2.29770710059172 0.215239178544577 0.600497137367914 GO:0001046 core promoter sequence-specific DNA binding 4/1014 44/18639 0.0909090909090909 1.67105970952125 0.216139944648741 0.600497137367914 GO:0001223 transcription coactivator binding 4/1014 44/18639 0.0909090909090909 1.67105970952125 0.216139944648741 0.600497137367914 GO:0030547 signaling receptor inhibitor activity 4/1014 44/18639 0.0909090909090909 1.67105970952125 0.216139944648741 0.600497137367914 GO:0031593 polyubiquitin modification-dependent protein binding 5/1014 59/18639 0.0847457627118644 1.55776752582489 0.216824540526809 0.600497137367914 GO:0004175 endopeptidase activity 26/1014 405/18639 0.0641975308641975 1.18005698005698 0.217317087203562 0.600497137367914 GO:0019210 kinase inhibitor activity 7/1014 90/18639 0.0777777777777778 1.42968441814596 0.217879492319332 0.600497137367914 GO:0140793 histone H2AXY142 phosphatase activity 7/1014 90/18639 0.0777777777777778 1.42968441814596 0.217879492319332 0.600497137367914 GO:0035925 mRNA 3'-UTR AU-rich region binding 3/1014 30/18639 0.1 1.83816568047337 0.222068087544874 0.603858943938868 GO:0043995 histone H4K5 acetyltransferase activity 3/1014 30/18639 0.1 1.83816568047337 0.222068087544874 0.603858943938868 GO:0043996 histone H4K8 acetyltransferase activity 3/1014 30/18639 0.1 1.83816568047337 0.222068087544874 0.603858943938868 GO:0043997 histone H4K12 acetyltransferase activity 3/1014 30/18639 0.1 1.83816568047337 0.222068087544874 0.603858943938868 GO:0048019 receptor antagonist activity 3/1014 30/18639 0.1 1.83816568047337 0.222068087544874 0.603858943938868 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 7/1014 91/18639 0.0769230769230769 1.41397360036413 0.225885137825625 0.612600493783094 GO:0140303 intramembrane lipid transporter activity 4/1014 45/18639 0.0888888888888889 1.63392504930966 0.227854875681036 0.61629895895642 GO:0004713 protein tyrosine kinase activity 10/1014 140/18639 0.0714285714285714 1.31297548605241 0.231790155804555 0.623995903099578 GO:0017022 myosin binding 6/1014 76/18639 0.0789473684210526 1.45118343195266 0.231927680798073 0.623995903099578 GO:0038191 neuropilin binding 2/1014 17/18639 0.117647058823529 2.16254785938044 0.235708418063646 0.624367017438348 GO:0048038 quinone binding 2/1014 17/18639 0.117647058823529 2.16254785938044 0.235708418063646 0.624367017438348 GO:0070403 NAD+ binding 2/1014 17/18639 0.117647058823529 2.16254785938044 0.235708418063646 0.624367017438348 GO:1901567 fatty acid derivative binding 2/1014 17/18639 0.117647058823529 2.16254785938044 0.235708418063646 0.624367017438348 GO:0008327 methyl-CpG binding 3/1014 31/18639 0.0967741935483871 1.77887001336133 0.236701759335084 0.624367017438348 GO:0070273 phosphatidylinositol-4-phosphate binding 3/1014 31/18639 0.0967741935483871 1.77887001336133 0.236701759335084 0.624367017438348 GO:0070325 lipoprotein particle receptor binding 3/1014 31/18639 0.0967741935483871 1.77887001336133 0.236701759335084 0.624367017438348 GO:0015026 coreceptor activity 5/1014 61/18639 0.0819672131147541 1.50669318071588 0.236977058732746 0.624367017438348 GO:0022884 macromolecule transmembrane transporter activity 3/1014 32/18639 0.09375 1.72328032544379 0.25149474862642 0.657506836383211 GO:0030515 snoRNA binding 3/1014 32/18639 0.09375 1.72328032544379 0.25149474862642 0.657506836383211 GO:0031369 translation initiation factor binding 3/1014 32/18639 0.09375 1.72328032544379 0.25149474862642 0.657506836383211 GO:0000900 mRNA regulatory element binding translation repressor activity 2/1014 18/18639 0.111111111111111 2.04240631163708 0.256275073883455 0.659827215542971 GO:0008525 phosphatidylcholine transporter activity 2/1014 18/18639 0.111111111111111 2.04240631163708 0.256275073883455 0.659827215542971 GO:0016854 racemase and epimerase activity 2/1014 18/18639 0.111111111111111 2.04240631163708 0.256275073883455 0.659827215542971 GO:0035615 clathrin adaptor activity 2/1014 18/18639 0.111111111111111 2.04240631163708 0.256275073883455 0.659827215542971 GO:0050811 GABA receptor binding 2/1014 18/18639 0.111111111111111 2.04240631163708 0.256275073883455 0.659827215542971 GO:0070628 proteasome binding 2/1014 18/18639 0.111111111111111 2.04240631163708 0.256275073883455 0.659827215542971 GO:1902936 phosphatidylinositol bisphosphate binding 8/1014 111/18639 0.0720720720720721 1.32480409403486 0.257111699281905 0.660309591337621 GO:0019955 cytokine binding 10/1014 144/18639 0.0694444444444444 1.27650394477318 0.258364599647287 0.661855913957912 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 9/1014 128/18639 0.0703125 1.29246024408284 0.261813730137816 0.669006441080801 GO:0008194 UDP-glycosyltransferase activity 10/1014 145/18639 0.0689655172413793 1.26770046929198 0.265162342343868 0.675674978932053 GO:0071889 14-3-3 protein binding 3/1014 33/18639 0.0909090909090909 1.67105970952125 0.266416584613327 0.675674978932053 GO:0140311 protein sequestering activity 3/1014 33/18639 0.0909090909090909 1.67105970952125 0.266416584613327 0.675674978932053 GO:0016407 acetyltransferase activity 7/1014 96/18639 0.0729166666666667 1.34032914201183 0.267307771068164 0.676248764120206 GO:0000049 tRNA binding 6/1014 80/18639 0.075 1.37862426035503 0.268657924939265 0.677977939610999 GO:0016853 isomerase activity 12/1014 180/18639 0.0666666666666667 1.22544378698225 0.275340959731032 0.683433978661159 GO:0001222 transcription corepressor binding 4/1014 49/18639 0.0816326530612245 1.50054341263132 0.276099221972893 0.683433978661159 GO:0016758 hexosyltransferase activity 13/1014 197/18639 0.065989847715736 1.2130027333073 0.276129895490805 0.683433978661159 GO:0016798 hydrolase activity, acting on glycosyl bonds 9/1014 130/18639 0.0692307692307692 1.27257624032772 0.276415116715547 0.683433978661159 GO:0003756 protein disulfide isomerase activity 2/1014 19/18639 0.105263157894737 1.93491124260355 0.276868042486133 0.683433978661159 GO:0005520 insulin-like growth factor binding 2/1014 19/18639 0.105263157894737 1.93491124260355 0.276868042486133 0.683433978661159 GO:0015245 fatty acid transmembrane transporter activity 2/1014 19/18639 0.105263157894737 1.93491124260355 0.276868042486133 0.683433978661159 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 2/1014 19/18639 0.105263157894737 1.93491124260355 0.276868042486133 0.683433978661159 GO:0120227 acyl-CoA binding 2/1014 19/18639 0.105263157894737 1.93491124260355 0.276868042486133 0.683433978661159 GO:0001618 virus receptor activity 6/1014 81/18639 0.0740740740740741 1.36160420775805 0.278061794688063 0.684718753505471 GO:0042277 peptide binding 16/1014 249/18639 0.0642570281124498 1.18115063805518 0.281651113868264 0.691882084067691 GO:0140272 exogenous protein binding 6/1014 82/18639 0.0731707317073171 1.34499927839515 0.287539953519694 0.704646102962719 GO:0015605 organophosphate ester transmembrane transporter activity 4/1014 50/18639 0.08 1.4705325443787 0.288425027558838 0.705115992854179 GO:0005154 epidermal growth factor receptor binding 3/1014 35/18639 0.0857142857142857 1.57557058326289 0.296530963511149 0.711717309062526 GO:0010485 histone H4 acetyltransferase activity 3/1014 35/18639 0.0857142857142857 1.57557058326289 0.296530963511149 0.711717309062526 GO:0043015 gamma-tubulin binding 3/1014 35/18639 0.0857142857142857 1.57557058326289 0.296530963511149 0.711717309062526 GO:0003899 DNA-directed 5'-3' RNA polymerase activity 2/1014 20/18639 0.1 1.83816568047337 0.297423654229669 0.711717309062526 GO:0005326 neurotransmitter transmembrane transporter activity 2/1014 20/18639 0.1 1.83816568047337 0.297423654229669 0.711717309062526 GO:0030742 GTP-dependent protein binding 2/1014 20/18639 0.1 1.83816568047337 0.297423654229669 0.711717309062526 GO:0042288 MHC class I protein binding 2/1014 20/18639 0.1 1.83816568047337 0.297423654229669 0.711717309062526 GO:0061608 nuclear import signal receptor activity 2/1014 20/18639 0.1 1.83816568047337 0.297423654229669 0.711717309062526 GO:0140939 histone H4 methyltransferase activity 2/1014 20/18639 0.1 1.83816568047337 0.297423654229669 0.711717309062526 GO:0019207 kinase regulator activity 18/1014 287/18639 0.0627177700348432 1.1528565243387 0.300416703992554 0.714103549050364 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 11/1014 167/18639 0.0658682634730539 1.21076781348546 0.30048220907952 0.714103549050364 GO:0061135 endopeptidase regulator activity 12/1014 184/18639 0.0652173913043478 1.19880370465655 0.300527353975965 0.714103549050364 GO:0043130 ubiquitin binding 7/1014 100/18639 0.07 1.28671597633136 0.301806637325177 0.71547167869395 GO:0005096 GTPase activator activity 17/1014 271/18639 0.0627306273062731 1.15309286228957 0.307111285444505 0.726353900690842 GO:0003777 microtubule motor activity 5/1014 68/18639 0.0735294117647059 1.35159241211277 0.310823543371262 0.733428175425925 GO:0009931 calcium-dependent protein serine/threonine kinase activity 2/1014 21/18639 0.0952380952380952 1.75063398140321 0.317885076261405 0.743193385190456 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 2/1014 21/18639 0.0952380952380952 1.75063398140321 0.317885076261405 0.743193385190456 GO:0051010 microtubule plus-end binding 2/1014 21/18639 0.0952380952380952 1.75063398140321 0.317885076261405 0.743193385190456 GO:0140312 cargo adaptor activity 2/1014 21/18639 0.0952380952380952 1.75063398140321 0.317885076261405 0.743193385190456 GO:0008238 exopeptidase activity 7/1014 102/18639 0.0686274509803922 1.26148625130526 0.319393438258827 0.745007171351439 GO:0140789 histone phosphatase activity 9/1014 136/18639 0.0661764705882353 1.2164331709015 0.32147007709598 0.746864660165786 GO:0008080 N-acetyltransferase activity 5/1014 69/18639 0.072463768115942 1.33200411628505 0.321658526207094 0.746864660165786 GO:0016860 intramolecular oxidoreductase activity 4/1014 53/18639 0.0754716981132075 1.38729485318745 0.325787943643028 0.748525845163797 GO:0140296 general transcription initiation factor binding 4/1014 53/18639 0.0754716981132075 1.38729485318745 0.325787943643028 0.748525845163797 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 6/1014 86/18639 0.0697674418604651 1.28244117242328 0.326054030882558 0.748525845163797 GO:0016209 antioxidant activity 6/1014 86/18639 0.0697674418604651 1.28244117242328 0.326054030882558 0.748525845163797 GO:0050660 flavin adenine dinucleotide binding 6/1014 86/18639 0.0697674418604651 1.28244117242328 0.326054030882558 0.748525845163797 GO:0023023 MHC protein complex binding 3/1014 37/18639 0.0810810810810811 1.49040460578922 0.326825916482215 0.74860801140183 GO:0005516 calmodulin binding 13/1014 207/18639 0.0628019323671498 1.15440356744705 0.3373190533071 0.769465745383048 GO:0034062 5'-3' RNA polymerase activity 2/1014 22/18639 0.0909090909090909 1.67105970952125 0.338201758295204 0.769465745383048 GO:0097747 RNA polymerase activity 2/1014 22/18639 0.0909090909090909 1.67105970952125 0.338201758295204 0.769465745383048 GO:0000146 microfilament motor activity 3/1014 38/18639 0.0789473684210526 1.45118343195266 0.341978359984209 0.774592410031047 GO:0043531 ADP binding 3/1014 38/18639 0.0789473684210526 1.45118343195266 0.341978359984209 0.774592410031047 GO:0140313 molecular sequestering activity 4/1014 55/18639 0.0727272727272727 1.336847767617 0.350871105930114 0.792968699402057 GO:0003730 mRNA 3'-UTR binding 16/1014 262/18639 0.0610687022900763 1.12254392700664 0.35316579589361 0.796384954376501 GO:0000217 DNA secondary structure binding 3/1014 39/18639 0.0769230769230769 1.41397360036413 0.357103287983305 0.801708706134704 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 3/1014 39/18639 0.0769230769230769 1.41397360036413 0.357103287983305 0.801708706134704 GO:0005158 insulin receptor binding 2/1014 23/18639 0.0869565217391304 1.59840493954206 0.358328918362706 0.802688347962274 GO:0046982 protein heterodimerization activity 22/1014 369/18639 0.0596205962059621 1.0959253379516 0.359493310773759 0.80352680671849 GO:0015144 carbohydrate transmembrane transporter activity 3/1014 40/18639 0.075 1.37862426035503 0.372179228094418 0.826785294814953 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 3/1014 40/18639 0.075 1.37862426035503 0.372179228094418 0.826785294814953 GO:0019787 ubiquitin-like protein transferase activity 28/1014 479/18639 0.058455114822547 1.07450185914936 0.374359573461941 0.826785294814953 GO:0004601 peroxidase activity 4/1014 57/18639 0.0701754385964912 1.28994082840237 0.375965245126242 0.826785294814953 GO:0001091 RNA polymerase II general transcription initiation factor binding 2/1014 24/18639 0.0833333333333333 1.53180473372781 0.378227065836168 0.826785294814953 GO:0015149 hexose transmembrane transporter activity 2/1014 24/18639 0.0833333333333333 1.53180473372781 0.378227065836168 0.826785294814953 GO:0055056 D-glucose transmembrane transporter activity 2/1014 24/18639 0.0833333333333333 1.53180473372781 0.378227065836168 0.826785294814953 GO:0016877 ligase activity, forming carbon-sulfur bonds 3/1014 41/18639 0.0731707317073171 1.34499927839515 0.38718601310404 0.826785294814953 GO:0140318 protein transporter activity 3/1014 41/18639 0.0731707317073171 1.34499927839515 0.38718601310404 0.826785294814953 GO:0003707 nuclear steroid receptor activity 2/1014 25/18639 0.08 1.4705325443787 0.397861559195681 0.826785294814953 GO:0008483 transaminase activity 2/1014 25/18639 0.08 1.4705325443787 0.397861559195681 0.826785294814953 GO:0004842 ubiquitin-protein transferase activity 26/1014 449/18639 0.0579064587973274 1.06441665238993 0.399640607637217 0.826785294814953 GO:0001786 phosphatidylserine binding 4/1014 59/18639 0.0677966101694915 1.24621402065991 0.400968698143234 0.826785294814953 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 4/1014 59/18639 0.0677966101694915 1.24621402065991 0.400968698143234 0.826785294814953 GO:0045309 protein phosphorylated amino acid binding 4/1014 59/18639 0.0677966101694915 1.24621402065991 0.400968698143234 0.826785294814953 GO:0070888 E-box binding 4/1014 59/18639 0.0677966101694915 1.24621402065991 0.400968698143234 0.826785294814953 GO:0004402 histone acetyltransferase activity 3/1014 42/18639 0.0714285714285714 1.31297548605241 0.402104762909688 0.826785294814953 GO:0016410 N-acyltransferase activity 6/1014 94/18639 0.0638297872340425 1.17329724285534 0.404545558142381 0.826785294814953 GO:0106310 protein serine kinase activity 21/1014 361/18639 0.0581717451523546 1.06929305512301 0.407582012689694 0.826785294814953 GO:0004867 serine-type endopeptidase inhibitor activity 6/1014 95/18639 0.0631578947368421 1.16094674556213 0.414367425578666 0.826785294814953 GO:0016791 phosphatase activity 16/1014 273/18639 0.0586080586080586 1.07731321932505 0.416112338095312 0.826785294814953 GO:0048156 tau protein binding 3/1014 43/18639 0.0697674418604651 1.28244117242328 0.416917861301163 0.826785294814953 GO:0005112 Notch binding 2/1014 26/18639 0.0769230769230769 1.41397360036413 0.417202196177821 0.826785294814953 GO:0005160 transforming growth factor beta receptor binding 2/1014 26/18639 0.0769230769230769 1.41397360036413 0.417202196177821 0.826785294814953 GO:0015145 monosaccharide transmembrane transporter activity 2/1014 26/18639 0.0769230769230769 1.41397360036413 0.417202196177821 0.826785294814953 GO:0030247 polysaccharide binding 2/1014 26/18639 0.0769230769230769 1.41397360036413 0.417202196177821 0.826785294814953 GO:0030507 spectrin binding 2/1014 26/18639 0.0769230769230769 1.41397360036413 0.417202196177821 0.826785294814953 GO:0034237 protein kinase A regulatory subunit binding 2/1014 26/18639 0.0769230769230769 1.41397360036413 0.417202196177821 0.826785294814953 GO:1901981 phosphatidylinositol phosphate binding 11/1014 185/18639 0.0594594594594595 1.09296337757876 0.425215898859133 0.826785294814953 GO:0000182 rDNA binding 1/1014 10/18639 0.1 1.83816568047337 0.428515008659492 0.826785294814953 GO:0001164 RNA polymerase I core promoter sequence-specific DNA binding 1/1014 10/18639 0.1 1.83816568047337 0.428515008659492 0.826785294814953 GO:0003680 minor groove of adenine-thymine-rich DNA binding 1/1014 10/18639 0.1 1.83816568047337 0.428515008659492 0.826785294814953 GO:0004090 carbonyl reductase (NADPH) activity 1/1014 10/18639 0.1 1.83816568047337 0.428515008659492 0.826785294814953 GO:0004445 inositol-polyphosphate 5-phosphatase activity 1/1014 10/18639 0.1 1.83816568047337 0.428515008659492 0.826785294814953 GO:0004955 prostaglandin receptor activity 1/1014 10/18639 0.1 1.83816568047337 0.428515008659492 0.826785294814953 GO:0005131 growth hormone receptor binding 1/1014 10/18639 0.1 1.83816568047337 0.428515008659492 0.826785294814953 GO:0005381 iron ion transmembrane transporter activity 1/1014 10/18639 0.1 1.83816568047337 0.428515008659492 0.826785294814953 GO:0005528 FK506 binding 1/1014 10/18639 0.1 1.83816568047337 0.428515008659492 0.826785294814953 GO:0008140 cAMP response element binding protein binding 1/1014 10/18639 0.1 1.83816568047337 0.428515008659492 0.826785294814953 GO:0008190 eukaryotic initiation factor 4E binding 1/1014 10/18639 0.1 1.83816568047337 0.428515008659492 0.826785294814953 GO:0008353 RNA polymerase II CTD heptapeptide repeat kinase activity 1/1014 10/18639 0.1 1.83816568047337 0.428515008659492 0.826785294814953 GO:0008641 ubiquitin-like modifier activating enzyme activity 1/1014 10/18639 0.1 1.83816568047337 0.428515008659492 0.826785294814953 GO:0015187 glycine transmembrane transporter activity 1/1014 10/18639 0.1 1.83816568047337 0.428515008659492 0.826785294814953 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen 1/1014 10/18639 0.1 1.83816568047337 0.428515008659492 0.826785294814953 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines 1/1014 10/18639 0.1 1.83816568047337 0.428515008659492 0.826785294814953 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor 1/1014 10/18639 0.1 1.83816568047337 0.428515008659492 0.826785294814953 GO:0016889 DNA endonuclease activity, producing 3'-phosphomonoesters 1/1014 10/18639 0.1 1.83816568047337 0.428515008659492 0.826785294814953 GO:0019911 structural constituent of myelin sheath 1/1014 10/18639 0.1 1.83816568047337 0.428515008659492 0.826785294814953 GO:0031957 very long-chain fatty acid-CoA ligase activity 1/1014 10/18639 0.1 1.83816568047337 0.428515008659492 0.826785294814953 GO:0036435 K48-linked polyubiquitin modification-dependent protein binding 1/1014 10/18639 0.1 1.83816568047337 0.428515008659492 0.826785294814953 GO:0043121 neurotrophin binding 1/1014 10/18639 0.1 1.83816568047337 0.428515008659492 0.826785294814953 GO:0051864 histone H3K36 demethylase activity 1/1014 10/18639 0.1 1.83816568047337 0.428515008659492 0.826785294814953 GO:1990763 arrestin family protein binding 1/1014 10/18639 0.1 1.83816568047337 0.428515008659492 0.826785294814953 GO:0015370 solute:sodium symporter activity 5/1014 79/18639 0.0632911392405063 1.1633960002996 0.430817010668887 0.826785294814953 GO:0043014 alpha-tubulin binding 3/1014 44/18639 0.0681818181818182 1.25329478214094 0.431608928373291 0.826785294814953 GO:0008168 methyltransferase activity 12/1014 204/18639 0.0588235294117647 1.08127392969022 0.432762358066979 0.826785294814953 GO:0023026 MHC class II protein complex binding 2/1014 27/18639 0.0740740740740741 1.36160420775805 0.436222834096671 0.826785294814953 GO:0015294 solute:monoatomic cation symporter activity 7/1014 116/18639 0.0603448275862069 1.10923791063048 0.444958092811117 0.826785294814953 GO:0004715 non-membrane spanning protein tyrosine kinase activity 3/1014 45/18639 0.0666666666666667 1.22544378698225 0.446162789279881 0.826785294814953 GO:0016755 aminoacyltransferase activity 28/1014 496/18639 0.0564516129032258 1.03767417446077 0.44765214423554 0.826785294814953 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 14/1014 243/18639 0.0576131687242798 1.05902549492293 0.451871510483736 0.826785294814953 GO:0051019 mitogen-activated protein kinase binding 2/1014 28/18639 0.0714285714285714 1.31297548605241 0.454901038272301 0.826785294814953 GO:0051119 sugar transmembrane transporter activity 2/1014 28/18639 0.0714285714285714 1.31297548605241 0.454901038272301 0.826785294814953 GO:0097718 disordered domain specific binding 2/1014 28/18639 0.0714285714285714 1.31297548605241 0.454901038272301 0.826785294814953 GO:0000014 single-stranded DNA endodeoxyribonuclease activity 1/1014 11/18639 0.0909090909090909 1.67105970952125 0.459621658571955 0.826785294814953 GO:0000099 sulfur amino acid transmembrane transporter activity 1/1014 11/18639 0.0909090909090909 1.67105970952125 0.459621658571955 0.826785294814953 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding 1/1014 11/18639 0.0909090909090909 1.67105970952125 0.459621658571955 0.826785294814953 GO:0001163 RNA polymerase I transcription regulatory region sequence-specific DNA binding 1/1014 11/18639 0.0909090909090909 1.67105970952125 0.459621658571955 0.826785294814953 GO:0003953 NAD+ nucleosidase activity 1/1014 11/18639 0.0909090909090909 1.67105970952125 0.459621658571955 0.826785294814953 GO:0004143 ATP-dependent diacylglycerol kinase activity 1/1014 11/18639 0.0909090909090909 1.67105970952125 0.459621658571955 0.826785294814953 GO:0004954 prostanoid receptor activity 1/1014 11/18639 0.0909090909090909 1.67105970952125 0.459621658571955 0.826785294814953 GO:0005536 D-glucose binding 1/1014 11/18639 0.0909090909090909 1.67105970952125 0.459621658571955 0.826785294814953 GO:0008172 S-methyltransferase activity 1/1014 11/18639 0.0909090909090909 1.67105970952125 0.459621658571955 0.826785294814953 GO:0010854 adenylate cyclase regulator activity 1/1014 11/18639 0.0909090909090909 1.67105970952125 0.459621658571955 0.826785294814953 GO:0016176 superoxide-generating NADPH oxidase activator activity 1/1014 11/18639 0.0909090909090909 1.67105970952125 0.459621658571955 0.826785294814953 GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor 1/1014 11/18639 0.0909090909090909 1.67105970952125 0.459621658571955 0.826785294814953 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 1/1014 11/18639 0.0909090909090909 1.67105970952125 0.459621658571955 0.826785294814953 GO:0016725 oxidoreductase activity, acting on CH or CH2 groups 1/1014 11/18639 0.0909090909090909 1.67105970952125 0.459621658571955 0.826785294814953 GO:0019206 nucleoside kinase activity 1/1014 11/18639 0.0909090909090909 1.67105970952125 0.459621658571955 0.826785294814953 GO:0019215 intermediate filament binding 1/1014 11/18639 0.0909090909090909 1.67105970952125 0.459621658571955 0.826785294814953 GO:0034056 estrogen response element binding 1/1014 11/18639 0.0909090909090909 1.67105970952125 0.459621658571955 0.826785294814953 GO:0034511 U3 snoRNA binding 1/1014 11/18639 0.0909090909090909 1.67105970952125 0.459621658571955 0.826785294814953 GO:0034713 type I transforming growth factor beta receptor binding 1/1014 11/18639 0.0909090909090909 1.67105970952125 0.459621658571955 0.826785294814953 GO:0047676 arachidonate-CoA ligase activity 1/1014 11/18639 0.0909090909090909 1.67105970952125 0.459621658571955 0.826785294814953 GO:0048407 platelet-derived growth factor binding 1/1014 11/18639 0.0909090909090909 1.67105970952125 0.459621658571955 0.826785294814953 GO:0050786 RAGE receptor binding 1/1014 11/18639 0.0909090909090909 1.67105970952125 0.459621658571955 0.826785294814953 GO:0050998 nitric-oxide synthase binding 1/1014 11/18639 0.0909090909090909 1.67105970952125 0.459621658571955 0.826785294814953 GO:0140537 transcription regulator activator activity 1/1014 11/18639 0.0909090909090909 1.67105970952125 0.459621658571955 0.826785294814953 GO:1990948 ubiquitin ligase inhibitor activity 1/1014 11/18639 0.0909090909090909 1.67105970952125 0.459621658571955 0.826785294814953 GO:0030276 clathrin binding 3/1014 46/18639 0.0652173913043478 1.19880370465655 0.46056543996543 0.826785294814953 GO:0030291 protein serine/threonine kinase inhibitor activity 3/1014 46/18639 0.0652173913043478 1.19880370465655 0.46056543996543 0.826785294814953 GO:0061659 ubiquitin-like protein ligase activity 21/1014 372/18639 0.0564516129032258 1.03767417446077 0.462743283532789 0.826785294814953 GO:0004676 3-phosphoinositide-dependent protein kinase activity 14/1014 245/18639 0.0571428571428571 1.05038038884193 0.464217560759186 0.826785294814953 GO:0004711 ribosomal protein S6 kinase activity 14/1014 245/18639 0.0571428571428571 1.05038038884193 0.464217560759186 0.826785294814953 GO:0035175 histone H3S10 kinase activity 14/1014 245/18639 0.0571428571428571 1.05038038884193 0.464217560759186 0.826785294814953 GO:0035979 histone H2AXS139 kinase activity 14/1014 245/18639 0.0571428571428571 1.05038038884193 0.464217560759186 0.826785294814953 GO:0044022 histone H3S28 kinase activity 14/1014 245/18639 0.0571428571428571 1.05038038884193 0.464217560759186 0.826785294814953 GO:0044023 histone H4S1 kinase activity 14/1014 245/18639 0.0571428571428571 1.05038038884193 0.464217560759186 0.826785294814953 GO:0044024 histone H2AS1 kinase activity 14/1014 245/18639 0.0571428571428571 1.05038038884193 0.464217560759186 0.826785294814953 GO:0044025 histone H2BS14 kinase activity 14/1014 245/18639 0.0571428571428571 1.05038038884193 0.464217560759186 0.826785294814953 GO:0072354 histone H3T3 kinase activity 14/1014 245/18639 0.0571428571428571 1.05038038884193 0.464217560759186 0.826785294814953 GO:0072371 histone H2AS121 kinase activity 14/1014 245/18639 0.0571428571428571 1.05038038884193 0.464217560759186 0.826785294814953 GO:0072518 Rho-dependent protein serine/threonine kinase activity 14/1014 245/18639 0.0571428571428571 1.05038038884193 0.464217560759186 0.826785294814953 GO:0140823 histone H2BS36 kinase activity 14/1014 245/18639 0.0571428571428571 1.05038038884193 0.464217560759186 0.826785294814953 GO:0140855 histone H3S57 kinase activity 14/1014 245/18639 0.0571428571428571 1.05038038884193 0.464217560759186 0.826785294814953 GO:0140995 histone H2A kinase activity 14/1014 245/18639 0.0571428571428571 1.05038038884193 0.464217560759186 0.826785294814953 GO:0140997 histone H4 kinase activity 14/1014 245/18639 0.0571428571428571 1.05038038884193 0.464217560759186 0.826785294814953 GO:0140998 histone H2B kinase activity 14/1014 245/18639 0.0571428571428571 1.05038038884193 0.464217560759186 0.826785294814953 GO:1990244 histone H2AT120 kinase activity 14/1014 245/18639 0.0571428571428571 1.05038038884193 0.464217560759186 0.826785294814953 GO:0004677 DNA-dependent protein kinase activity 14/1014 246/18639 0.0569105691056911 1.0461105498629 0.470378552136943 0.826785294814953 GO:0140857 histone H3T45 kinase activity 14/1014 246/18639 0.0569105691056911 1.0461105498629 0.470378552136943 0.826785294814953 GO:0003785 actin monomer binding 2/1014 29/18639 0.0689655172413793 1.26770046929198 0.473217756636856 0.826785294814953 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 2/1014 29/18639 0.0689655172413793 1.26770046929198 0.473217756636856 0.826785294814953 GO:0035250 UDP-galactosyltransferase activity 2/1014 29/18639 0.0689655172413793 1.26770046929198 0.473217756636856 0.826785294814953 GO:0097472 cyclin-dependent protein kinase activity 2/1014 29/18639 0.0689655172413793 1.26770046929198 0.473217756636856 0.826785294814953 GO:0001540 amyloid-beta binding 5/1014 83/18639 0.0602409638554217 1.10732872317673 0.473734496268823 0.826785294814953 GO:0030165 PDZ domain binding 5/1014 83/18639 0.0602409638554217 1.10732872317673 0.473734496268823 0.826785294814953 GO:0061733 protein-lysine-acetyltransferase activity 3/1014 47/18639 0.0638297872340425 1.17329724285534 0.474804010444365 0.826785294814953 GO:0035402 histone H3T11 kinase activity 14/1014 247/18639 0.0566801619433198 1.04187528447883 0.47652963692083 0.826785294814953 GO:0035403 histone H3T6 kinase activity 14/1014 247/18639 0.0566801619433198 1.04187528447883 0.47652963692083 0.826785294814953 GO:0035091 phosphatidylinositol binding 16/1014 284/18639 0.0563380281690141 1.03558629885824 0.47951413384909 0.826785294814953 GO:0004679 AMP-activated protein kinase activity 14/1014 248/18639 0.0564516129032258 1.03767417446077 0.48266942494662 0.826785294814953 GO:0016757 glycosyltransferase activity 15/1014 267/18639 0.0561797752808989 1.03267734858055 0.486969411619663 0.826785294814953 GO:0030295 protein kinase activator activity 8/1014 139/18639 0.0575539568345324 1.05793708228683 0.486979547225465 0.826785294814953 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 3/1014 48/18639 0.0625 1.14885355029586 0.488866726136584 0.826785294814953 GO:0000340 RNA 7-methylguanosine cap binding 1/1014 12/18639 0.0833333333333333 1.53180473372781 0.489036713232039 0.826785294814953 GO:0000995 RNA polymerase III general transcription initiation factor activity 1/1014 12/18639 0.0833333333333333 1.53180473372781 0.489036713232039 0.826785294814953 GO:0004126 cytidine deaminase activity 1/1014 12/18639 0.0833333333333333 1.53180473372781 0.489036713232039 0.826785294814953 GO:0004300 enoyl-CoA hydratase activity 1/1014 12/18639 0.0833333333333333 1.53180473372781 0.489036713232039 0.826785294814953 GO:0005025 transforming growth factor beta receptor activity, type I 1/1014 12/18639 0.0833333333333333 1.53180473372781 0.489036713232039 0.826785294814953 GO:0005026 transforming growth factor beta receptor activity, type II 1/1014 12/18639 0.0833333333333333 1.53180473372781 0.489036713232039 0.826785294814953 GO:0005095 GTPase inhibitor activity 1/1014 12/18639 0.0833333333333333 1.53180473372781 0.489036713232039 0.826785294814953 GO:0005247 voltage-gated chloride channel activity 1/1014 12/18639 0.0833333333333333 1.53180473372781 0.489036713232039 0.826785294814953 GO:0005436 sodium:phosphate symporter activity 1/1014 12/18639 0.0833333333333333 1.53180473372781 0.489036713232039 0.826785294814953 GO:0005527 macrolide binding 1/1014 12/18639 0.0833333333333333 1.53180473372781 0.489036713232039 0.826785294814953 GO:0008179 adenylate cyclase binding 1/1014 12/18639 0.0833333333333333 1.53180473372781 0.489036713232039 0.826785294814953 GO:0008504 monoamine transmembrane transporter activity 1/1014 12/18639 0.0833333333333333 1.53180473372781 0.489036713232039 0.826785294814953 GO:0010853 cyclase activator activity 1/1014 12/18639 0.0833333333333333 1.53180473372781 0.489036713232039 0.826785294814953 GO:0016361 activin receptor activity, type I 1/1014 12/18639 0.0833333333333333 1.53180473372781 0.489036713232039 0.826785294814953 GO:0016362 activin receptor activity, type II 1/1014 12/18639 0.0833333333333333 1.53180473372781 0.489036713232039 0.826785294814953 GO:0017002 activin receptor activity 1/1014 12/18639 0.0833333333333333 1.53180473372781 0.489036713232039 0.826785294814953 GO:0031543 peptidyl-proline dioxygenase activity 1/1014 12/18639 0.0833333333333333 1.53180473372781 0.489036713232039 0.826785294814953 GO:0043047 single-stranded telomeric DNA binding 1/1014 12/18639 0.0833333333333333 1.53180473372781 0.489036713232039 0.826785294814953 GO:0045295 gamma-catenin binding 1/1014 12/18639 0.0833333333333333 1.53180473372781 0.489036713232039 0.826785294814953 GO:0070679 inositol 1,4,5 trisphosphate binding 1/1014 12/18639 0.0833333333333333 1.53180473372781 0.489036713232039 0.826785294814953 GO:0097371 MDM2/MDM4 family protein binding 1/1014 12/18639 0.0833333333333333 1.53180473372781 0.489036713232039 0.826785294814953 GO:0001965 G-protein alpha-subunit binding 2/1014 30/18639 0.0666666666666667 1.22544378698225 0.491157018714854 0.826785294814953 GO:0016769 transferase activity, transferring nitrogenous groups 2/1014 30/18639 0.0666666666666667 1.22544378698225 0.491157018714854 0.826785294814953 GO:0031210 phosphatidylcholine binding 2/1014 30/18639 0.0666666666666667 1.22544378698225 0.491157018714854 0.826785294814953 GO:0005253 monoatomic anion channel activity 6/1014 103/18639 0.058252427184466 1.0707761245476 0.491843759452356 0.826785294814953 GO:0016741 transferase activity, transferring one-carbon groups 12/1014 215/18639 0.0558139534883721 1.02595293793863 0.506010784759376 0.845078073738736 GO:0016878 acid-thiol ligase activity 2/1014 31/18639 0.0645161290322581 1.18591334224089 0.50870565729277 0.845078073738736 GO:0005548 phospholipid transporter activity 4/1014 68/18639 0.0588235294117647 1.08127392969022 0.51004776737544 0.845078073738736 GO:0140223 general transcription initiation factor activity 4/1014 68/18639 0.0588235294117647 1.08127392969022 0.51004776737544 0.845078073738736 GO:0004866 endopeptidase inhibitor activity 9/1014 161/18639 0.0559006211180124 1.02754603256276 0.51545283261725 0.845078073738736 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 1/1014 13/18639 0.0769230769230769 1.41397360036413 0.516852076563907 0.845078073738736 GO:0005172 vascular endothelial growth factor receptor binding 1/1014 13/18639 0.0769230769230769 1.41397360036413 0.516852076563907 0.845078073738736 GO:0008035 high-density lipoprotein particle binding 1/1014 13/18639 0.0769230769230769 1.41397360036413 0.516852076563907 0.845078073738736 GO:0008253 5'-nucleotidase activity 1/1014 13/18639 0.0769230769230769 1.41397360036413 0.516852076563907 0.845078073738736 GO:0008417 fucosyltransferase activity 1/1014 13/18639 0.0769230769230769 1.41397360036413 0.516852076563907 0.845078073738736 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors 1/1014 13/18639 0.0769230769230769 1.41397360036413 0.516852076563907 0.845078073738736 GO:0019104 DNA N-glycosylase activity 1/1014 13/18639 0.0769230769230769 1.41397360036413 0.516852076563907 0.845078073738736 GO:0019855 calcium channel inhibitor activity 1/1014 13/18639 0.0769230769230769 1.41397360036413 0.516852076563907 0.845078073738736 GO:0035673 oligopeptide transmembrane transporter activity 1/1014 13/18639 0.0769230769230769 1.41397360036413 0.516852076563907 0.845078073738736 GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity 1/1014 13/18639 0.0769230769230769 1.41397360036413 0.516852076563907 0.845078073738736 GO:0140333 glycerophospholipid flippase activity 1/1014 13/18639 0.0769230769230769 1.41397360036413 0.516852076563907 0.845078073738736 GO:0140852 histone ubiquitin ligase activity 1/1014 13/18639 0.0769230769230769 1.41397360036413 0.516852076563907 0.845078073738736 GO:0008378 galactosyltransferase activity 2/1014 32/18639 0.0625 1.14885355029586 0.52585305120386 0.847279239658081 GO:0015106 bicarbonate transmembrane transporter activity 2/1014 32/18639 0.0625 1.14885355029586 0.52585305120386 0.847279239658081 GO:0043425 bHLH transcription factor binding 2/1014 32/18639 0.0625 1.14885355029586 0.52585305120386 0.847279239658081 GO:0071813 lipoprotein particle binding 2/1014 32/18639 0.0625 1.14885355029586 0.52585305120386 0.847279239658081 GO:0071814 protein-lipid complex binding 2/1014 32/18639 0.0625 1.14885355029586 0.52585305120386 0.847279239658081 GO:0140142 nucleocytoplasmic carrier activity 2/1014 32/18639 0.0625 1.14885355029586 0.52585305120386 0.847279239658081 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 10/1014 181/18639 0.0552486187845304 1.0155611494328 0.526277718081682 0.847279239658081 GO:0019956 chemokine binding 2/1014 33/18639 0.0606060606060606 1.1140398063475 0.542590887758088 0.847279239658081 GO:0030296 protein tyrosine kinase activator activity 2/1014 33/18639 0.0606060606060606 1.1140398063475 0.542590887758088 0.847279239658081 GO:0004705 JUN kinase activity 1/1014 14/18639 0.0714285714285714 1.31297548605241 0.543154664041852 0.847279239658081 GO:0005161 platelet-derived growth factor receptor binding 1/1014 14/18639 0.0714285714285714 1.31297548605241 0.543154664041852 0.847279239658081 GO:0005313 L-glutamate transmembrane transporter activity 1/1014 14/18639 0.0714285714285714 1.31297548605241 0.543154664041852 0.847279239658081 GO:0005344 oxygen carrier activity 1/1014 14/18639 0.0714285714285714 1.31297548605241 0.543154664041852 0.847279239658081 GO:0008174 mRNA methyltransferase activity 1/1014 14/18639 0.0714285714285714 1.31297548605241 0.543154664041852 0.847279239658081 GO:0008191 metalloendopeptidase inhibitor activity 1/1014 14/18639 0.0714285714285714 1.31297548605241 0.543154664041852 0.847279239658081 GO:0015926 glucosidase activity 1/1014 14/18639 0.0714285714285714 1.31297548605241 0.543154664041852 0.847279239658081 GO:0030983 mismatched DNA binding 1/1014 14/18639 0.0714285714285714 1.31297548605241 0.543154664041852 0.847279239658081 GO:0031404 chloride ion binding 1/1014 14/18639 0.0714285714285714 1.31297548605241 0.543154664041852 0.847279239658081 GO:0032036 myosin heavy chain binding 1/1014 14/18639 0.0714285714285714 1.31297548605241 0.543154664041852 0.847279239658081 GO:0034236 protein kinase A catalytic subunit binding 1/1014 14/18639 0.0714285714285714 1.31297548605241 0.543154664041852 0.847279239658081 GO:0042043 neurexin family protein binding 1/1014 14/18639 0.0714285714285714 1.31297548605241 0.543154664041852 0.847279239658081 GO:0046030 inositol trisphosphate phosphatase activity 1/1014 14/18639 0.0714285714285714 1.31297548605241 0.543154664041852 0.847279239658081 GO:0098821 BMP receptor activity 1/1014 14/18639 0.0714285714285714 1.31297548605241 0.543154664041852 0.847279239658081 GO:0098847 sequence-specific single stranded DNA binding 1/1014 14/18639 0.0714285714285714 1.31297548605241 0.543154664041852 0.847279239658081 GO:1901612 cardiolipin binding 1/1014 14/18639 0.0714285714285714 1.31297548605241 0.543154664041852 0.847279239658081 GO:1990825 sequence-specific mRNA binding 1/1014 14/18639 0.0714285714285714 1.31297548605241 0.543154664041852 0.847279239658081 GO:0030159 signaling receptor complex adaptor activity 3/1014 52/18639 0.0576923076923077 1.0604802002731 0.543159612293954 0.847279239658081 GO:0015293 symporter activity 8/1014 146/18639 0.0547945205479452 1.00721407149226 0.543236214083625 0.847279239658081 GO:0061630 ubiquitin protein ligase activity 19/1014 353/18639 0.0538243626062323 0.989380961161305 0.553061067659398 0.847279239658081 GO:0016251 RNA polymerase II general transcription initiation factor activity 3/1014 53/18639 0.0566037735849057 1.04047113989059 0.55620191241301 0.847279239658081 GO:0017046 peptide hormone binding 3/1014 53/18639 0.0566037735849057 1.04047113989059 0.55620191241301 0.847279239658081 GO:0034212 protein N-acetyltransferase activity 3/1014 53/18639 0.0566037735849057 1.04047113989059 0.55620191241301 0.847279239658081 GO:0051018 protein kinase A binding 3/1014 53/18639 0.0566037735849057 1.04047113989059 0.55620191241301 0.847279239658081 GO:0019209 kinase activator activity 8/1014 148/18639 0.0540540540540541 0.993603070526147 0.558866013472637 0.847279239658081 GO:0008175 tRNA methyltransferase activity 2/1014 34/18639 0.0588235294117647 1.08127392969022 0.558912943444187 0.847279239658081 GO:0016831 carboxy-lyase activity 2/1014 34/18639 0.0588235294117647 1.08127392969022 0.558912943444187 0.847279239658081 GO:0051427 hormone receptor binding 2/1014 34/18639 0.0588235294117647 1.08127392969022 0.558912943444187 0.847279239658081 GO:0008509 monoatomic anion transmembrane transporter activity 8/1014 149/18639 0.0536912751677852 0.98693459354275 0.566594890899014 0.847279239658081 GO:0043539 protein serine/threonine kinase activator activity 4/1014 73/18639 0.0547945205479452 1.00721407149226 0.566634804208715 0.847279239658081 GO:0004467 long-chain fatty acid-CoA ligase activity 1/1014 15/18639 0.0666666666666667 1.22544378698225 0.568026673204888 0.847279239658081 GO:0004865 protein serine/threonine phosphatase inhibitor activity 1/1014 15/18639 0.0666666666666667 1.22544378698225 0.568026673204888 0.847279239658081 GO:0004953 icosanoid receptor activity 1/1014 15/18639 0.0666666666666667 1.22544378698225 0.568026673204888 0.847279239658081 GO:0005041 low-density lipoprotein particle receptor activity 1/1014 15/18639 0.0666666666666667 1.22544378698225 0.568026673204888 0.847279239658081 GO:0005402 carbohydrate:monoatomic cation symporter activity 1/1014 15/18639 0.0666666666666667 1.22544378698225 0.568026673204888 0.847279239658081 GO:0008242 omega peptidase activity 1/1014 15/18639 0.0666666666666667 1.22544378698225 0.568026673204888 0.847279239658081 GO:0008252 nucleotidase activity 1/1014 15/18639 0.0666666666666667 1.22544378698225 0.568026673204888 0.847279239658081 GO:0010181 FMN binding 1/1014 15/18639 0.0666666666666667 1.22544378698225 0.568026673204888 0.847279239658081 GO:0015929 hexosaminidase activity 1/1014 15/18639 0.0666666666666667 1.22544378698225 0.568026673204888 0.847279239658081 GO:0016846 carbon-sulfur lyase activity 1/1014 15/18639 0.0666666666666667 1.22544378698225 0.568026673204888 0.847279239658081 GO:0031386 protein tag activity 1/1014 15/18639 0.0666666666666667 1.22544378698225 0.568026673204888 0.847279239658081 GO:0034483 heparan sulfate sulfotransferase activity 1/1014 15/18639 0.0666666666666667 1.22544378698225 0.568026673204888 0.847279239658081 GO:0047372 monoacylglycerol lipase activity 1/1014 15/18639 0.0666666666666667 1.22544378698225 0.568026673204888 0.847279239658081 GO:0050780 dopamine receptor binding 1/1014 15/18639 0.0666666666666667 1.22544378698225 0.568026673204888 0.847279239658081 GO:0055105 ubiquitin-protein transferase inhibitor activity 1/1014 15/18639 0.0666666666666667 1.22544378698225 0.568026673204888 0.847279239658081 GO:0120283 protein serine/threonine kinase binding 1/1014 15/18639 0.0666666666666667 1.22544378698225 0.568026673204888 0.847279239658081 GO:0140776 protein-containing complex destabilizing activity 1/1014 15/18639 0.0666666666666667 1.22544378698225 0.568026673204888 0.847279239658081 GO:0141047 molecular tag activity 1/1014 15/18639 0.0666666666666667 1.22544378698225 0.568026673204888 0.847279239658081 GO:0003925 G protein activity 3/1014 54/18639 0.0555555555555556 1.02120315581854 0.569018407754641 0.847279239658081 GO:0015485 cholesterol binding 3/1014 54/18639 0.0555555555555556 1.02120315581854 0.569018407754641 0.847279239658081 GO:0050661 NADP binding 3/1014 54/18639 0.0555555555555556 1.02120315581854 0.569018407754641 0.847279239658081 GO:0051287 NAD binding 3/1014 54/18639 0.0555555555555556 1.02120315581854 0.569018407754641 0.847279239658081 GO:0030414 peptidase inhibitor activity 9/1014 169/18639 0.0532544378698225 0.978904800252092 0.574616758628046 0.853411291400759 GO:0000175 3'-5'-RNA exonuclease activity 2/1014 35/18639 0.0571428571428571 1.05038038884193 0.574814881621947 0.853411291400759 GO:0042562 hormone binding 5/1014 94/18639 0.0531914893617021 0.977747702379454 0.585067393232482 0.854548464186563 GO:0033218 amide binding 13/1014 247/18639 0.0526315789473684 0.967455621301775 0.589339808119963 0.854548464186563 GO:0004869 cysteine-type endopeptidase inhibitor activity 2/1014 36/18639 0.0555555555555556 1.02120315581854 0.590294066007991 0.854548464186563 GO:0005484 SNAP receptor activity 2/1014 36/18639 0.0555555555555556 1.02120315581854 0.590294066007991 0.854548464186563 GO:0045505 dynein intermediate chain binding 2/1014 36/18639 0.0555555555555556 1.02120315581854 0.590294066007991 0.854548464186563 GO:0055106 ubiquitin-protein transferase regulator activity 2/1014 36/18639 0.0555555555555556 1.02120315581854 0.590294066007991 0.854548464186563 GO:0003688 DNA replication origin binding 1/1014 16/18639 0.0625 1.14885355029586 0.591545839515576 0.854548464186563 GO:0004707 MAP kinase activity 1/1014 16/18639 0.0625 1.14885355029586 0.591545839515576 0.854548464186563 GO:0008142 oxysterol binding 1/1014 16/18639 0.0625 1.14885355029586 0.591545839515576 0.854548464186563 GO:0008296 3'-5'-DNA exonuclease activity 1/1014 16/18639 0.0625 1.14885355029586 0.591545839515576 0.854548464186563 GO:0015378 sodium:chloride symporter activity 1/1014 16/18639 0.0625 1.14885355029586 0.591545839515576 0.854548464186563 GO:0015562 efflux transmembrane transporter activity 1/1014 16/18639 0.0625 1.14885355029586 0.591545839515576 0.854548464186563 GO:0016675 oxidoreductase activity, acting on a heme group of donors 1/1014 16/18639 0.0625 1.14885355029586 0.591545839515576 0.854548464186563 GO:0022858 alanine transmembrane transporter activity 1/1014 16/18639 0.0625 1.14885355029586 0.591545839515576 0.854548464186563 GO:0031435 mitogen-activated protein kinase kinase kinase binding 1/1014 16/18639 0.0625 1.14885355029586 0.591545839515576 0.854548464186563 GO:0043023 ribosomal large subunit binding 1/1014 16/18639 0.0625 1.14885355029586 0.591545839515576 0.854548464186563 GO:0061809 NAD+ nucleosidase activity, cyclic ADP-ribose generating 1/1014 16/18639 0.0625 1.14885355029586 0.591545839515576 0.854548464186563 GO:0097027 ubiquitin-protein transferase activator activity 1/1014 16/18639 0.0625 1.14885355029586 0.591545839515576 0.854548464186563 GO:0140327 flippase activity 1/1014 16/18639 0.0625 1.14885355029586 0.591545839515576 0.854548464186563 GO:0170055 lipid transmembrane transporter activity 3/1014 56/18639 0.0535714285714286 0.984731614539307 0.593953667816295 0.856809759105208 GO:0042578 phosphoric ester hydrolase activity 19/1014 363/18639 0.0523415977961433 0.962125287300112 0.602780406921787 0.868178073558247 GO:0004896 cytokine receptor activity 5/1014 96/18639 0.0520833333333333 0.957377958579882 0.603912225989837 0.868178073558247 GO:0015932 nucleobase-containing compound transmembrane transporter activity 3/1014 57/18639 0.0526315789473684 0.967455621301775 0.60606413574352 0.868178073558247 GO:0005092 GDP-dissociation inhibitor activity 1/1014 17/18639 0.0588235294117647 1.08127392969022 0.613785678356322 0.868178073558247 GO:0008429 phosphatidylethanolamine binding 1/1014 17/18639 0.0588235294117647 1.08127392969022 0.613785678356322 0.868178073558247 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 1/1014 17/18639 0.0588235294117647 1.08127392969022 0.613785678356322 0.868178073558247 GO:0016805 dipeptidase activity 1/1014 17/18639 0.0588235294117647 1.08127392969022 0.613785678356322 0.868178073558247 GO:0030169 low-density lipoprotein particle binding 1/1014 17/18639 0.0588235294117647 1.08127392969022 0.613785678356322 0.868178073558247 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 1/1014 17/18639 0.0588235294117647 1.08127392969022 0.613785678356322 0.868178073558247 GO:0030548 acetylcholine receptor regulator activity 1/1014 17/18639 0.0588235294117647 1.08127392969022 0.613785678356322 0.868178073558247 GO:0031489 myosin V binding 1/1014 17/18639 0.0588235294117647 1.08127392969022 0.613785678356322 0.868178073558247 GO:0032977 membrane insertase activity 1/1014 17/18639 0.0588235294117647 1.08127392969022 0.613785678356322 0.868178073558247 GO:0045236 CXCR chemokine receptor binding 1/1014 17/18639 0.0588235294117647 1.08127392969022 0.613785678356322 0.868178073558247 GO:0070402 NADPH binding 1/1014 17/18639 0.0588235294117647 1.08127392969022 0.613785678356322 0.868178073558247 GO:0008408 3'-5' exonuclease activity 3/1014 58/18639 0.0517241379310345 0.950775351968986 0.617932124140022 0.870885071241053 GO:0005109 frizzled binding 2/1014 38/18639 0.0526315789473684 0.967455621301775 0.619981112663247 0.870885071241053 GO:0005501 retinoid binding 2/1014 38/18639 0.0526315789473684 0.967455621301775 0.619981112663247 0.870885071241053 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 2/1014 38/18639 0.0526315789473684 0.967455621301775 0.619981112663247 0.870885071241053 GO:0019840 isoprenoid binding 2/1014 38/18639 0.0526315789473684 0.967455621301775 0.619981112663247 0.870885071241053 GO:0004879 nuclear receptor activity 3/1014 59/18639 0.0508474576271186 0.934660515494935 0.629555164818421 0.873623249052882 GO:0015459 potassium channel regulator activity 3/1014 59/18639 0.0508474576271186 0.934660515494935 0.629555164818421 0.873623249052882 GO:0000400 four-way junction DNA binding 1/1014 18/18639 0.0555555555555556 1.02120315581854 0.634815713913549 0.873623249052882 GO:0008308 voltage-gated monoatomic anion channel activity 1/1014 18/18639 0.0555555555555556 1.02120315581854 0.634815713913549 0.873623249052882 GO:0008409 5'-3' exonuclease activity 1/1014 18/18639 0.0555555555555556 1.02120315581854 0.634815713913549 0.873623249052882 GO:0015172 acidic amino acid transmembrane transporter activity 1/1014 18/18639 0.0555555555555556 1.02120315581854 0.634815713913549 0.873623249052882 GO:0015373 monoatomic anion:sodium symporter activity 1/1014 18/18639 0.0555555555555556 1.02120315581854 0.634815713913549 0.873623249052882 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 1/1014 18/18639 0.0555555555555556 1.02120315581854 0.634815713913549 0.873623249052882 GO:0017128 phospholipid scramblase activity 1/1014 18/18639 0.0555555555555556 1.02120315581854 0.634815713913549 0.873623249052882 GO:0030228 lipoprotein particle receptor activity 1/1014 18/18639 0.0555555555555556 1.02120315581854 0.634815713913549 0.873623249052882 GO:0031690 adrenergic receptor binding 1/1014 18/18639 0.0555555555555556 1.02120315581854 0.634815713913549 0.873623249052882 GO:0034185 apolipoprotein binding 1/1014 18/18639 0.0555555555555556 1.02120315581854 0.634815713913549 0.873623249052882 GO:0070064 proline-rich region binding 1/1014 18/18639 0.0555555555555556 1.02120315581854 0.634815713913549 0.873623249052882 GO:0099602 neurotransmitter receptor regulator activity 1/1014 18/18639 0.0555555555555556 1.02120315581854 0.634815713913549 0.873623249052882 GO:1901611 phosphatidylglycerol binding 1/1014 18/18639 0.0555555555555556 1.02120315581854 0.634815713913549 0.873623249052882 GO:0098531 ligand-modulated transcription factor activity 3/1014 60/18639 0.05 0.919082840236686 0.640931391754618 0.880847601911415 GO:0004532 RNA exonuclease activity 2/1014 40/18639 0.05 0.919082840236686 0.647980803582514 0.88306581496781 GO:0050997 quaternary ammonium group binding 2/1014 40/18639 0.05 0.919082840236686 0.647980803582514 0.88306581496781 GO:0061791 GTPase motor activity 2/1014 40/18639 0.05 0.919082840236686 0.647980803582514 0.88306581496781 GO:0071949 FAD binding 2/1014 40/18639 0.05 0.919082840236686 0.647980803582514 0.88306581496781 GO:1990606 membrane scission GTPase motor activity 2/1014 40/18639 0.05 0.919082840236686 0.647980803582514 0.88306581496781 GO:0005229 intracellularly calcium-gated chloride channel activity 1/1014 19/18639 0.0526315789473684 0.967455621301775 0.654701695659517 0.88306581496781 GO:0005346 purine ribonucleotide transmembrane transporter activity 1/1014 19/18639 0.0526315789473684 0.967455621301775 0.654701695659517 0.88306581496781 GO:0008301 DNA binding, bending 1/1014 19/18639 0.0526315789473684 0.967455621301775 0.654701695659517 0.88306581496781 GO:0031420 alkali metal ion binding 1/1014 19/18639 0.0526315789473684 0.967455621301775 0.654701695659517 0.88306581496781 GO:0034987 immunoglobulin receptor binding 1/1014 19/18639 0.0526315789473684 0.967455621301775 0.654701695659517 0.88306581496781 GO:0046624 sphingolipid transporter activity 1/1014 19/18639 0.0526315789473684 0.967455621301775 0.654701695659517 0.88306581496781 GO:0050145 nucleoside monophosphate kinase activity 1/1014 19/18639 0.0526315789473684 0.967455621301775 0.654701695659517 0.88306581496781 GO:0140036 ubiquitin-modified protein reader activity 1/1014 19/18639 0.0526315789473684 0.967455621301775 0.654701695659517 0.88306581496781 GO:0141147 intracellularly calcium-gated channel activity 1/1014 19/18639 0.0526315789473684 0.967455621301775 0.654701695659517 0.88306581496781 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 6/1014 122/18639 0.0491803278688525 0.904015908429528 0.657772374241689 0.884997274504942 GO:0001727 lipid kinase activity 2/1014 41/18639 0.0487804878048781 0.896666185596767 0.661354895401923 0.884997274504942 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 2/1014 41/18639 0.0487804878048781 0.896666185596767 0.661354895401923 0.884997274504942 GO:0008137 NADH dehydrogenase (ubiquinone) activity 2/1014 41/18639 0.0487804878048781 0.896666185596767 0.661354895401923 0.884997274504942 GO:0015175 neutral L-amino acid transmembrane transporter activity 2/1014 41/18639 0.0487804878048781 0.896666185596767 0.661354895401923 0.884997274504942 GO:0042287 MHC protein binding 2/1014 41/18639 0.0487804878048781 0.896666185596767 0.661354895401923 0.884997274504942 GO:0005254 chloride channel activity 4/1014 83/18639 0.0481927710843374 0.885862978541385 0.667973338217864 0.889469257926052 GO:0001972 retinoic acid binding 1/1014 20/18639 0.05 0.919082840236686 0.673505803103193 0.889469257926052 GO:0010851 cyclase regulator activity 1/1014 20/18639 0.05 0.919082840236686 0.673505803103193 0.889469257926052 GO:0015095 magnesium ion transmembrane transporter activity 1/1014 20/18639 0.05 0.919082840236686 0.673505803103193 0.889469257926052 GO:0016408 C-acyltransferase activity 1/1014 20/18639 0.05 0.919082840236686 0.673505803103193 0.889469257926052 GO:0016505 peptidase activator activity involved in apoptotic process 1/1014 20/18639 0.05 0.919082840236686 0.673505803103193 0.889469257926052 GO:0052745 inositol phosphate phosphatase activity 1/1014 20/18639 0.05 0.919082840236686 0.673505803103193 0.889469257926052 GO:0005507 copper ion binding 3/1014 63/18639 0.0476190476190476 0.875316990701606 0.673568788301921 0.889469257926052 GO:0004520 DNA endonuclease activity 2/1014 42/18639 0.0476190476190476 0.875316990701606 0.674317402026535 0.889469257926052 GO:0019894 kinesin binding 2/1014 42/18639 0.0476190476190476 0.875316990701606 0.674317402026535 0.889469257926052 GO:0051879 Hsp90 protein binding 2/1014 42/18639 0.0476190476190476 0.875316990701606 0.674317402026535 0.889469257926052 GO:0004527 exonuclease activity 4/1014 84/18639 0.0476190476190476 0.875316990701606 0.677156660918979 0.892057414708033 GO:0004536 DNA nuclease activity 3/1014 64/18639 0.046875 0.861640162721893 0.683949864062044 0.895590720657137 GO:0008200 ion channel inhibitor activity 2/1014 43/18639 0.0465116279069767 0.854960781615522 0.68687347718387 0.895590720657137 GO:0008375 acetylglucosaminyltransferase activity 2/1014 43/18639 0.0465116279069767 0.854960781615522 0.68687347718387 0.895590720657137 GO:0005543 phospholipid binding 25/1014 497/18639 0.0503018108651912 0.92463062398057 0.687033386730979 0.895590720657137 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 1/1014 21/18639 0.0476190476190476 0.875316990701606 0.691286839445282 0.895590720657137 GO:0005123 death receptor binding 1/1014 21/18639 0.0476190476190476 0.875316990701606 0.691286839445282 0.895590720657137 GO:0005248 voltage-gated sodium channel activity 1/1014 21/18639 0.0476190476190476 0.875316990701606 0.691286839445282 0.895590720657137 GO:0008373 sialyltransferase activity 1/1014 21/18639 0.0476190476190476 0.875316990701606 0.691286839445282 0.895590720657137 GO:0015125 bile acid transmembrane transporter activity 1/1014 21/18639 0.0476190476190476 0.875316990701606 0.691286839445282 0.895590720657137 GO:0019200 carbohydrate kinase activity 1/1014 21/18639 0.0476190476190476 0.875316990701606 0.691286839445282 0.895590720657137 GO:0051428 peptide hormone receptor binding 1/1014 21/18639 0.0476190476190476 0.875316990701606 0.691286839445282 0.895590720657137 GO:0070182 DNA polymerase binding 1/1014 21/18639 0.0476190476190476 0.875316990701606 0.691286839445282 0.895590720657137 GO:0072542 protein phosphatase activator activity 1/1014 21/18639 0.0476190476190476 0.875316990701606 0.691286839445282 0.895590720657137 GO:0003954 NADH dehydrogenase activity 2/1014 44/18639 0.0454545454545455 0.835529854760624 0.699028931889135 0.902173126562501 GO:0016248 channel inhibitor activity 2/1014 44/18639 0.0454545454545455 0.835529854760624 0.699028931889135 0.902173126562501 GO:0019205 nucleobase-containing compound kinase activity 2/1014 44/18639 0.0454545454545455 0.835529854760624 0.699028931889135 0.902173126562501 GO:0005243 gap junction channel activity 1/1014 22/18639 0.0454545454545455 0.835529854760624 0.708100414738143 0.905056267105172 GO:0008093 cytoskeletal anchor activity 1/1014 22/18639 0.0454545454545455 0.835529854760624 0.708100414738143 0.905056267105172 GO:0015377 chloride:monoatomic cation symporter activity 1/1014 22/18639 0.0454545454545455 0.835529854760624 0.708100414738143 0.905056267105172 GO:0050321 tau-protein kinase activity 1/1014 22/18639 0.0454545454545455 0.835529854760624 0.708100414738143 0.905056267105172 GO:0070034 telomerase RNA binding 1/1014 22/18639 0.0454545454545455 0.835529854760624 0.708100414738143 0.905056267105172 GO:0140035 ubiquitin-like protein reader activity 1/1014 22/18639 0.0454545454545455 0.835529854760624 0.708100414738143 0.905056267105172 GO:0008514 organic anion transmembrane transporter activity 13/1014 269/18639 0.0483271375464684 0.888332856734344 0.709244813219319 0.905056267105172 GO:0042605 peptide antigen binding 2/1014 45/18639 0.0444444444444444 0.816962524654832 0.71079014782445 0.905056267105172 GO:0046915 transition metal ion transmembrane transporter activity 2/1014 45/18639 0.0444444444444444 0.816962524654832 0.71079014782445 0.905056267105172 GO:0141110 transporter inhibitor activity 2/1014 45/18639 0.0444444444444444 0.816962524654832 0.71079014782445 0.905056267105172 GO:0140098 catalytic activity, acting on RNA 19/1014 387/18639 0.0490956072351421 0.902458602816385 0.711052072189805 0.905056267105172 GO:0008173 RNA methyltransferase activity 3/1014 67/18639 0.0447761194029851 0.823059259913451 0.713607236610173 0.907173199540682 GO:0030145 manganese ion binding 3/1014 68/18639 0.0441176470588235 0.810955447267665 0.723002289036391 0.907900251718699 GO:0032934 sterol binding 3/1014 68/18639 0.0441176470588235 0.810955447267665 0.723002289036391 0.907900251718699 GO:0000295 adenine nucleotide transmembrane transporter activity 1/1014 23/18639 0.0434782608695652 0.799202469771032 0.723999119118845 0.907900251718699 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 1/1014 23/18639 0.0434782608695652 0.799202469771032 0.723999119118845 0.907900251718699 GO:0005283 amino acid:sodium symporter activity 1/1014 23/18639 0.0434782608695652 0.799202469771032 0.723999119118845 0.907900251718699 GO:0008171 O-methyltransferase activity 1/1014 23/18639 0.0434782608695652 0.799202469771032 0.723999119118845 0.907900251718699 GO:0016493 C-C chemokine receptor activity 1/1014 23/18639 0.0434782608695652 0.799202469771032 0.723999119118845 0.907900251718699 GO:0042171 lysophosphatidic acid acyltransferase activity 1/1014 23/18639 0.0434782608695652 0.799202469771032 0.723999119118845 0.907900251718699 GO:0071617 lysophospholipid acyltransferase activity 1/1014 23/18639 0.0434782608695652 0.799202469771032 0.723999119118845 0.907900251718699 GO:0140103 catalytic activity, acting on a glycoprotein 1/1014 23/18639 0.0434782608695652 0.799202469771032 0.723999119118845 0.907900251718699 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 1/1014 23/18639 0.0434782608695652 0.799202469771032 0.723999119118845 0.907900251718699 GO:0005179 hormone activity 6/1014 132/18639 0.0454545454545455 0.835529854760624 0.730136491982497 0.910753680757223 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 6/1014 132/18639 0.0454545454545455 0.835529854760624 0.730136491982497 0.910753680757223 GO:0001784 phosphotyrosine residue binding 2/1014 47/18639 0.0425531914893617 0.782198161903563 0.733157775414447 0.910753680757223 GO:0140359 ABC-type transporter activity 2/1014 47/18639 0.0425531914893617 0.782198161903563 0.733157775414447 0.910753680757223 GO:0005200 structural constituent of cytoskeleton 5/1014 112/18639 0.0446428571428571 0.820609678782756 0.7356010048407 0.910753680757223 GO:0072341 modified amino acid binding 4/1014 91/18639 0.043956043956044 0.80798491449379 0.736442331232387 0.910753680757223 GO:0004806 triacylglycerol lipase activity 1/1014 24/18639 0.0416666666666667 0.765902366863905 0.739032686652874 0.910753680757223 GO:0005315 phosphate transmembrane transporter activity 1/1014 24/18639 0.0416666666666667 0.765902366863905 0.739032686652874 0.910753680757223 GO:0005540 hyaluronic acid binding 1/1014 24/18639 0.0416666666666667 0.765902366863905 0.739032686652874 0.910753680757223 GO:0015295 solute:proton symporter activity 1/1014 24/18639 0.0416666666666667 0.765902366863905 0.739032686652874 0.910753680757223 GO:0019957 C-C chemokine binding 1/1014 24/18639 0.0416666666666667 0.765902366863905 0.739032686652874 0.910753680757223 GO:0050699 WW domain binding 1/1014 24/18639 0.0416666666666667 0.765902366863905 0.739032686652874 0.910753680757223 GO:0008028 monocarboxylic acid transmembrane transporter activity 3/1014 70/18639 0.0428571428571429 0.787785291631446 0.741067906015347 0.910753680757223 GO:0043178 alcohol binding 4/1014 92/18639 0.0434782608695652 0.799202469771032 0.744201199246183 0.910753680757223 GO:0052689 carboxylic ester hydrolase activity 4/1014 92/18639 0.0434782608695652 0.799202469771032 0.744201199246183 0.910753680757223 GO:0000030 mannosyltransferase activity 1/1014 25/18639 0.04 0.735266272189349 0.753248150296924 0.910753680757223 GO:0004709 MAP kinase kinase kinase activity 1/1014 25/18639 0.04 0.735266272189349 0.753248150296924 0.910753680757223 GO:0005537 D-mannose binding 1/1014 25/18639 0.04 0.735266272189349 0.753248150296924 0.910753680757223 GO:0008139 nuclear localization sequence binding 1/1014 25/18639 0.04 0.735266272189349 0.753248150296924 0.910753680757223 GO:0015296 monoatomic anion:monoatomic cation symporter activity 1/1014 25/18639 0.04 0.735266272189349 0.753248150296924 0.910753680757223 GO:0015645 fatty acid ligase activity 1/1014 25/18639 0.04 0.735266272189349 0.753248150296924 0.910753680757223 GO:0016895 DNA exonuclease activity, producing 5'-phosphomonoesters 1/1014 25/18639 0.04 0.735266272189349 0.753248150296924 0.910753680757223 GO:0017025 TBP-class protein binding 1/1014 25/18639 0.04 0.735266272189349 0.753248150296924 0.910753680757223 GO:0017056 structural constituent of nuclear pore 1/1014 25/18639 0.04 0.735266272189349 0.753248150296924 0.910753680757223 GO:0019211 phosphatase activator activity 1/1014 25/18639 0.04 0.735266272189349 0.753248150296924 0.910753680757223 GO:0019706 protein-cysteine S-palmitoyltransferase activity 1/1014 25/18639 0.04 0.735266272189349 0.753248150296924 0.910753680757223 GO:0019707 protein-cysteine S-acyltransferase activity 1/1014 25/18639 0.04 0.735266272189349 0.753248150296924 0.910753680757223 GO:0120020 cholesterol transfer activity 1/1014 25/18639 0.04 0.735266272189349 0.753248150296924 0.910753680757223 GO:0120515 fatty acid-CoA ligase activity 1/1014 25/18639 0.04 0.735266272189349 0.753248150296924 0.910753680757223 GO:0005525 GTP binding 18/1014 378/18639 0.0476190476190476 0.875316990701606 0.753416795921713 0.910753680757223 GO:0035254 glutamate receptor binding 2/1014 49/18639 0.0408163265306122 0.750271706315662 0.754035987411585 0.910753680757223 GO:0032813 tumor necrosis factor receptor superfamily binding 2/1014 50/18639 0.04 0.735266272189349 0.763936539809987 0.915168683410254 GO:0001637 G protein-coupled chemoattractant receptor activity 1/1014 26/18639 0.0384615384615385 0.706986800182066 0.766689988461688 0.915168683410254 GO:0004435 phosphatidylinositol phospholipase C activity 1/1014 26/18639 0.0384615384615385 0.706986800182066 0.766689988461688 0.915168683410254 GO:0004529 DNA exonuclease activity 1/1014 26/18639 0.0384615384615385 0.706986800182066 0.766689988461688 0.915168683410254 GO:0004950 chemokine receptor activity 1/1014 26/18639 0.0384615384615385 0.706986800182066 0.766689988461688 0.915168683410254 GO:0005227 calcium-activated cation channel activity 1/1014 26/18639 0.0384615384615385 0.706986800182066 0.766689988461688 0.915168683410254 GO:0015216 purine nucleotide transmembrane transporter activity 1/1014 26/18639 0.0384615384615385 0.706986800182066 0.766689988461688 0.915168683410254 GO:0019865 immunoglobulin binding 1/1014 26/18639 0.0384615384615385 0.706986800182066 0.766689988461688 0.915168683410254 GO:0043548 phosphatidylinositol 3-kinase binding 1/1014 26/18639 0.0384615384615385 0.706986800182066 0.766689988461688 0.915168683410254 GO:0052742 phosphatidylinositol kinase activity 1/1014 26/18639 0.0384615384615385 0.706986800182066 0.766689988461688 0.915168683410254 GO:0016830 carbon-carbon lyase activity 2/1014 51/18639 0.0392156862745098 0.720849286460146 0.773489150444689 0.920615642405663 GO:0070851 growth factor receptor binding 6/1014 139/18639 0.0431654676258993 0.793452811715125 0.773938833915967 0.920615642405663 GO:0004683 calcium/calmodulin-dependent protein kinase activity 1/1014 27/18639 0.037037037037037 0.680802103879027 0.779400263629573 0.920615642405663 GO:0005104 fibroblast growth factor receptor binding 1/1014 27/18639 0.037037037037037 0.680802103879027 0.779400263629573 0.920615642405663 GO:0005385 zinc ion transmembrane transporter activity 1/1014 27/18639 0.037037037037037 0.680802103879027 0.779400263629573 0.920615642405663 GO:0008395 steroid hydroxylase activity 1/1014 27/18639 0.037037037037037 0.680802103879027 0.779400263629573 0.920615642405663 GO:0016405 CoA-ligase activity 1/1014 27/18639 0.037037037037037 0.680802103879027 0.779400263629573 0.920615642405663 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors 1/1014 27/18639 0.037037037037037 0.680802103879027 0.779400263629573 0.920615642405663 GO:0035255 ionotropic glutamate receptor binding 1/1014 27/18639 0.037037037037037 0.680802103879027 0.779400263629573 0.920615642405663 GO:0019789 SUMO transferase activity 1/1014 28/18639 0.0357142857142857 0.656487743026205 0.79141875345762 0.929414402155196 GO:0046875 ephrin receptor binding 1/1014 28/18639 0.0357142857142857 0.656487743026205 0.79141875345762 0.929414402155196 GO:0050698 proteoglycan sulfotransferase activity 1/1014 28/18639 0.0357142857142857 0.656487743026205 0.79141875345762 0.929414402155196 GO:0051537 2 iron, 2 sulfur cluster binding 1/1014 28/18639 0.0357142857142857 0.656487743026205 0.79141875345762 0.929414402155196 GO:0051959 dynein light intermediate chain binding 1/1014 28/18639 0.0357142857142857 0.656487743026205 0.79141875345762 0.929414402155196 GO:0015108 chloride transmembrane transporter activity 5/1014 121/18639 0.0413223140495868 0.759572595236931 0.794112085542612 0.931501719719535 GO:0004181 metallocarboxypeptidase activity 1/1014 29/18639 0.0344827586206897 0.633850234645991 0.802783074772648 0.938425732234233 GO:0005416 amino acid:monoatomic cation symporter activity 1/1014 29/18639 0.0344827586206897 0.633850234645991 0.802783074772648 0.938425732234233 GO:0016417 S-acyltransferase activity 1/1014 29/18639 0.0344827586206897 0.633850234645991 0.802783074772648 0.938425732234233 GO:0046943 carboxylic acid transmembrane transporter activity 8/1014 188/18639 0.0425531914893617 0.782198161903563 0.808496836917119 0.94232208480404 GO:0005342 organic acid transmembrane transporter activity 8/1014 189/18639 0.0423280423280423 0.778059547290317 0.813025331410374 0.94232208480404 GO:0008106 alcohol dehydrogenase (NADP+) activity 1/1014 30/18639 0.0333333333333333 0.612721893491124 0.813528800843606 0.94232208480404 GO:0015215 nucleotide transmembrane transporter activity 1/1014 30/18639 0.0333333333333333 0.612721893491124 0.813528800843606 0.94232208480404 GO:0022839 monoatomic ion-gated channel activity 1/1014 30/18639 0.0333333333333333 0.612721893491124 0.813528800843606 0.94232208480404 GO:0031624 ubiquitin conjugating enzyme binding 1/1014 30/18639 0.0333333333333333 0.612721893491124 0.813528800843606 0.94232208480404 GO:0051721 protein phosphatase 2A binding 1/1014 30/18639 0.0333333333333333 0.612721893491124 0.813528800843606 0.94232208480404 GO:0098918 structural constituent of synapse 1/1014 30/18639 0.0333333333333333 0.612721893491124 0.813528800843606 0.94232208480404 GO:0005164 tumor necrosis factor receptor binding 1/1014 31/18639 0.032258064516129 0.592956671120443 0.823689572295301 0.947070237342252 GO:0005452 solute:inorganic anion antiporter activity 1/1014 31/18639 0.032258064516129 0.592956671120443 0.823689572295301 0.947070237342252 GO:0016411 acylglycerol O-acyltransferase activity 1/1014 31/18639 0.032258064516129 0.592956671120443 0.823689572295301 0.947070237342252 GO:0017147 Wnt-protein binding 1/1014 31/18639 0.032258064516129 0.592956671120443 0.823689572295301 0.947070237342252 GO:0072349 modified amino acid transmembrane transporter activity 1/1014 31/18639 0.032258064516129 0.592956671120443 0.823689572295301 0.947070237342252 GO:0015101 organic cation transmembrane transporter activity 3/1014 81/18639 0.037037037037037 0.680802103879027 0.824146666713759 0.947070237342252 GO:0030971 receptor tyrosine kinase binding 3/1014 81/18639 0.037037037037037 0.680802103879027 0.824146666713759 0.947070237342252 GO:0019001 guanyl nucleotide binding 18/1014 400/18639 0.045 0.827174556213018 0.828316799054438 0.949716104440094 GO:0032561 guanyl ribonucleotide binding 18/1014 400/18639 0.045 0.827174556213018 0.828316799054438 0.949716104440094 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 2/1014 58/18639 0.0344827586206897 0.633850234645991 0.831338960943715 0.952107796486214 GO:0042910 xenobiotic transmembrane transporter activity 1/1014 32/18639 0.03125 0.574426775147929 0.833297202007928 0.952205903867486 GO:0120015 sterol transfer activity 1/1014 32/18639 0.03125 0.574426775147929 0.833297202007928 0.952205903867486 GO:0019239 deaminase activity 1/1014 33/18639 0.0303030303030303 0.557019903173749 0.842381774328235 0.9614398947935 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 2/1014 60/18639 0.0333333333333333 0.612721893491124 0.845229014913041 0.9614398947935 GO:0005496 steroid binding 4/1014 108/18639 0.037037037037037 0.680802103879027 0.845664806565061 0.9614398947935 GO:0004252 serine-type endopeptidase activity 7/1014 176/18639 0.0397727272727273 0.731088622915546 0.849296331771052 0.9614398947935 GO:0005506 iron ion binding 6/1014 154/18639 0.038961038961039 0.716168446937678 0.849478870787493 0.9614398947935 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 1/1014 34/18639 0.0294117647058824 0.54063696484511 0.850971738900479 0.9614398947935 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 1/1014 34/18639 0.0294117647058824 0.54063696484511 0.850971738900479 0.9614398947935 GO:0019825 oxygen binding 1/1014 34/18639 0.0294117647058824 0.54063696484511 0.850971738900479 0.9614398947935 GO:0030332 cyclin binding 1/1014 34/18639 0.0294117647058824 0.54063696484511 0.850971738900479 0.9614398947935 GO:0090482 vitamin transmembrane transporter activity 1/1014 34/18639 0.0294117647058824 0.54063696484511 0.850971738900479 0.9614398947935 GO:0016836 hydro-lyase activity 2/1014 61/18639 0.0327868852459016 0.602677272286352 0.851777133932098 0.9614398947935 GO:0015179 L-amino acid transmembrane transporter activity 2/1014 62/18639 0.032258064516129 0.592956671120443 0.858071747435537 0.966480749334755 GO:0008081 phosphoric diester hydrolase activity 3/1014 87/18639 0.0344827586206897 0.633850234645991 0.859039095418254 0.966480749334755 GO:0005343 organic acid:sodium symporter activity 1/1014 35/18639 0.0285714285714286 0.525190194420964 0.859093999408671 0.966480749334755 GO:1901682 sulfur compound transmembrane transporter activity 2/1014 63/18639 0.0317460317460317 0.583544660467737 0.86412102478418 0.968691379630146 GO:0016651 oxidoreductase activity, acting on NAD(P)H 3/1014 88/18639 0.0340909090909091 0.626647391070468 0.864225024861088 0.968691379630146 GO:0004033 aldo-keto reductase (NADPH) activity 1/1014 36/18639 0.0277777777777778 0.51060157790927 0.866773997505833 0.968691379630146 GO:0004190 aspartic-type endopeptidase activity 1/1014 36/18639 0.0277777777777778 0.51060157790927 0.866773997505833 0.968691379630146 GO:0016409 palmitoyltransferase activity 1/1014 36/18639 0.0277777777777778 0.51060157790927 0.866773997505833 0.968691379630146 GO:0044390 ubiquitin-like protein conjugating enzyme binding 1/1014 36/18639 0.0277777777777778 0.51060157790927 0.866773997505833 0.968691379630146 GO:0022829 wide pore channel activity 1/1014 37/18639 0.027027027027027 0.496801535263074 0.87403579219105 0.97466491300252 GO:0070001 aspartic-type peptidase activity 1/1014 37/18639 0.027027027027027 0.496801535263074 0.87403579219105 0.97466491300252 GO:0140767 enzyme-substrate adaptor activity 5/1014 139/18639 0.0359712230215827 0.661210676429271 0.88027098720525 0.978314195225622 GO:0008083 growth factor activity 6/1014 162/18639 0.037037037037037 0.680802103879027 0.880493801681965 0.978314195225622 GO:0042887 amide transmembrane transporter activity 1/1014 38/18639 0.0263157894736842 0.483727810650888 0.880902134880991 0.978314195225622 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 9/1014 229/18639 0.0393013100436681 0.722423193199142 0.881156148305477 0.978314195225622 GO:0000287 magnesium ion binding 9/1014 230/18639 0.0391304347826087 0.719282222793929 0.884109427545052 0.980522669371121 GO:0015081 sodium ion transmembrane transporter activity 6/1014 164/18639 0.0365853658536585 0.672499639197575 0.887349362396625 0.982024208483331 GO:0016776 phosphotransferase activity, phosphate group as acceptor 1/1014 39/18639 0.0256410256410256 0.471324533454711 0.887394540409224 0.982024208483331 GO:0015103 inorganic anion transmembrane transporter activity 6/1014 165/18639 0.0363636363636364 0.668423883808499 0.89065034071755 0.983832312401784 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 2/1014 68/18639 0.0294117647058824 0.54063696484511 0.890963185567397 0.983832312401784 GO:0071855 neuropeptide receptor binding 1/1014 40/18639 0.025 0.459541420118343 0.893533354174012 0.985600239907777 GO:0001530 lipopolysaccharide binding 1/1014 41/18639 0.024390243902439 0.448333092798384 0.899337815643314 0.989855582802219 GO:0017080 sodium channel regulator activity 1/1014 41/18639 0.024390243902439 0.448333092798384 0.899337815643314 0.989855582802219 GO:0042056 chemoattractant activity 1/1014 42/18639 0.0238095238095238 0.437658495350803 0.904826118414455 0.994819635056758 GO:0042626 ATPase-coupled transmembrane transporter activity 3/1014 98/18639 0.0306122448979592 0.562703779736747 0.907493606021651 0.996674943114492 GO:0008236 serine-type peptidase activity 7/1014 194/18639 0.0360824742268041 0.663255657902763 0.90853036401167 0.996737195469113 GO:0004712 protein serine/threonine/tyrosine kinase activity 1/1014 43/18639 0.0232558139534884 0.427480390807761 0.910015467015183 0.997290657278493 GO:0017171 serine hydrolase activity 7/1014 198/18639 0.0353535353535354 0.649856553702707 0.918581719579427 0.99999998391923 GO:0051539 4 iron, 4 sulfur cluster binding 1/1014 45/18639 0.0222222222222222 0.408481262327416 0.919561493868182 0.99999998391923 GO:0019003 GDP binding 2/1014 75/18639 0.0266666666666667 0.490177514792899 0.920340555447237 0.99999998391923 GO:0015171 amino acid transmembrane transporter activity 3/1014 102/18639 0.0294117647058824 0.54063696484511 0.920986416968228 0.99999998391923 GO:0004180 carboxypeptidase activity 1/1014 46/18639 0.0217391304347826 0.399601234885516 0.923948104883438 0.99999998391923 GO:0004722 protein serine/threonine phosphatase activity 3/1014 103/18639 0.029126213592233 0.535388062273798 0.924066217837248 0.99999998391923 GO:0005319 lipid transporter activity 6/1014 178/18639 0.0337078651685393 0.619606409148328 0.926579275221538 0.99999998391923 GO:0005504 fatty acid binding 1/1014 47/18639 0.0212765957446809 0.391099080951781 0.928095720741459 0.99999998391923 GO:0043495 protein-membrane adaptor activity 1/1014 47/18639 0.0212765957446809 0.391099080951781 0.928095720741459 0.99999998391923 GO:0099095 ligand-gated monoatomic anion channel activity 1/1014 47/18639 0.0212765957446809 0.391099080951781 0.928095720741459 0.99999998391923 GO:0016298 lipase activity 4/1014 130/18639 0.0307692307692308 0.565589440145653 0.928178564255427 0.99999998391923 GO:0140375 immune receptor activity 5/1014 156/18639 0.032051282051282 0.589155666818389 0.931319104653305 0.99999998391923 GO:0016879 ligase activity, forming carbon-nitrogen bonds 1/1014 48/18639 0.0208333333333333 0.382951183431953 0.932017350429936 0.99999998391923 GO:0016835 carbon-oxygen lyase activity 2/1014 79/18639 0.0253164556962025 0.465358400119841 0.93360192351714 0.99999998391923 GO:0033293 monocarboxylic acid binding 2/1014 79/18639 0.0253164556962025 0.465358400119841 0.93360192351714 0.99999998391923 GO:0016763 pentosyltransferase activity 1/1014 49/18639 0.0204081632653061 0.375135853157831 0.935725295492818 0.99999998391923 GO:0033192 calmodulin-dependent protein phosphatase activity 2/1014 81/18639 0.0246913580246914 0.453868069252685 0.939421008601221 0.99999998391923 GO:0140791 histone H2AXS140 phosphatase activity 2/1014 81/18639 0.0246913580246914 0.453868069252685 0.939421008601221 0.99999998391923 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 2/1014 81/18639 0.0246913580246914 0.453868069252685 0.939421008601221 0.99999998391923 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 2/1014 81/18639 0.0246913580246914 0.453868069252685 0.939421008601221 0.99999998391923 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 2/1014 81/18639 0.0246913580246914 0.453868069252685 0.939421008601221 0.99999998391923 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 2/1014 81/18639 0.0246913580246914 0.453868069252685 0.939421008601221 0.99999998391923 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 2/1014 81/18639 0.0246913580246914 0.453868069252685 0.939421008601221 0.99999998391923 GO:1990439 MAP kinase serine/threonine phosphatase activity 2/1014 81/18639 0.0246913580246914 0.453868069252685 0.939421008601221 0.99999998391923 GO:0004620 phospholipase activity 3/1014 109/18639 0.0275229357798165 0.505917159763314 0.940344700509193 0.99999998391923 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 2/1014 82/18639 0.024390243902439 0.448333092798384 0.942145714392197 0.99999998391923 GO:0033549 MAP kinase phosphatase activity 2/1014 82/18639 0.024390243902439 0.448333092798384 0.942145714392197 0.99999998391923 GO:0016779 nucleotidyltransferase activity 4/1014 136/18639 0.0294117647058824 0.54063696484511 0.942377989882081 0.99999998391923 GO:0005272 sodium channel activity 1/1014 51/18639 0.0196078431372549 0.360424643230073 0.942546029226362 0.99999998391923 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 2/1014 83/18639 0.0240963855421687 0.442931489270692 0.944753633120027 0.99999998391923 GO:0031406 carboxylic acid binding 6/1014 187/18639 0.0320855614973262 0.589785779831029 0.944936322917596 0.99999998391923 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 1/1014 52/18639 0.0192307692307692 0.353493400091033 0.94568021936863 0.99999998391923 GO:0017018 myosin phosphatase activity 2/1014 84/18639 0.0238095238095238 0.437658495350803 0.947249391556827 0.99999998391923 GO:0043177 organic acid binding 6/1014 189/18639 0.0317460317460317 0.583544660467737 0.948410726429649 0.99999998391923 GO:0005246 calcium channel regulator activity 1/1014 53/18639 0.0188679245283019 0.346823713296863 0.948643594714851 0.99999998391923 GO:0008146 sulfotransferase activity 1/1014 53/18639 0.0188679245283019 0.346823713296863 0.948643594714851 0.99999998391923 GO:0015399 primary active transmembrane transporter activity 5/1014 166/18639 0.0301204819277108 0.553664361588365 0.951306665061131 0.99999998391923 GO:0016874 ligase activity 5/1014 167/18639 0.029940119760479 0.550349006129752 0.952982611242255 0.99999998391923 GO:0015291 secondary active transmembrane transporter activity 10/1014 287/18639 0.0348432055749129 0.640475846854834 0.953479536236701 0.99999998391923 GO:0008374 O-acyltransferase activity 1/1014 55/18639 0.0181818181818182 0.33421194190425 0.954094598247434 0.99999998391923 GO:0030170 pyridoxal phosphate binding 1/1014 56/18639 0.0178571428571429 0.328243871513102 0.956599337667209 0.99999998391923 GO:0070279 vitamin B6 binding 1/1014 57/18639 0.0175438596491228 0.322485207100592 0.958967538259441 0.99999998391923 GO:0036002 pre-mRNA binding 1/1014 59/18639 0.0169491525423729 0.311553505164978 0.963323662692706 0.99999998391923 GO:0019842 vitamin binding 4/1014 150/18639 0.0266666666666667 0.490177514792899 0.966097327254039 0.99999998391923 GO:0005125 cytokine activity 7/1014 234/18639 0.0299145299145299 0.549878622363829 0.973569956832558 0.99999998391923 GO:0120013 lipid transfer activity 1/1014 65/18639 0.0153846153846154 0.282794720072827 0.973810408322117 0.99999998391923 GO:0003924 GTPase activity 11/1014 331/18639 0.0332326283987915 0.610870769945834 0.97394570532794 0.99999998391923 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 3/1014 130/18639 0.0230769230769231 0.42419208010924 0.975176862782782 0.99999998391923 GO:0005262 calcium channel activity 3/1014 131/18639 0.0229007633587786 0.42095397262749 0.976218217952436 0.99999998391923 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 1/1014 67/18639 0.0149253731343284 0.274353086637817 0.976591934832478 0.99999998391923 GO:0099106 ion channel regulator activity 4/1014 160/18639 0.025 0.459541420118343 0.977079803578066 0.99999998391923 GO:0015297 antiporter activity 3/1014 135/18639 0.0222222222222222 0.408481262327416 0.979982653835616 0.99999998391923 GO:0016782 transferase activity, transferring sulphur-containing groups 1/1014 70/18639 0.0142857142857143 0.262595097210482 0.980220715598809 0.99999998391923 GO:0004497 monooxygenase activity 2/1014 106/18639 0.0188679245283019 0.346823713296863 0.981345156390156 0.99999998391923 GO:0042379 chemokine receptor binding 1/1014 72/18639 0.0138888888888889 0.255300788954635 0.982321970297333 0.99999998391923 GO:0016247 channel regulator activity 4/1014 168/18639 0.0238095238095238 0.437658495350803 0.983355499885269 0.99999998391923 GO:0003684 damaged DNA binding 1/1014 74/18639 0.0135135135135135 0.248400767631537 0.984200194569267 0.99999998391923 GO:0005126 cytokine receptor binding 8/1014 275/18639 0.0290909090909091 0.534739107046799 0.984398708981814 0.99999998391923 GO:0141108 transporter regulator activity 4/1014 170/18639 0.0235294117647059 0.432509571876088 0.984648427969207 0.99999998391923 GO:0051536 iron-sulfur cluster binding 1/1014 76/18639 0.0131578947368421 0.241863905325444 0.985879040335041 0.99999998391923 GO:0016829 lyase activity 5/1014 200/18639 0.025 0.459541420118343 0.986011063978243 0.99999998391923 GO:0051540 metal cluster binding 1/1014 77/18639 0.012987012987013 0.238722815645893 0.98665039480901 0.99999998391923 GO:0045182 translation regulator activity 11/1014 356/18639 0.0308988764044944 0.567972541719301 0.987481256773618 0.99999998391923 GO:0015085 calcium ion transmembrane transporter activity 3/1014 147/18639 0.0204081632653061 0.375135853157831 0.988158540972854 0.99999998391923 GO:0009055 electron transfer activity 2/1014 116/18639 0.0172413793103448 0.316925117322995 0.98850642583519 0.99999998391923 GO:0022804 active transmembrane transporter activity 15/1014 457/18639 0.0328227571115974 0.603336656610516 0.989314164048889 0.99999998391923 GO:0022853 active monoatomic ion transmembrane transporter activity 2/1014 118/18639 0.0169491525423729 0.311553505164978 0.989575236071983 0.99999998391923 GO:0004518 nuclease activity 5/1014 209/18639 0.0239234449760766 0.439752555137171 0.990116582908557 0.99999998391923 GO:0004540 RNA nuclease activity 2/1014 121/18639 0.0165289256198347 0.303829038094772 0.990998893161791 0.99999998391923 GO:0008528 G protein-coupled peptide receptor activity 2/1014 122/18639 0.0163934426229508 0.301338636143176 0.99142980625629 0.99999998391923 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 2/1014 122/18639 0.0163934426229508 0.301338636143176 0.99142980625629 0.99999998391923 GO:0004519 endonuclease activity 2/1014 127/18639 0.015748031496063 0.289474910310767 0.993299381445307 0.99999998391923 GO:0001653 peptide receptor activity 2/1014 128/18639 0.015625 0.287213387573964 0.993622183752788 0.99999998391923 GO:0140101 catalytic activity, acting on a tRNA 2/1014 139/18639 0.0143884892086331 0.264484270571708 0.996306709241756 0.99999998391923 GO:0003823 antigen binding 3/1014 174/18639 0.0172413793103448 0.316925117322995 0.996499846872937 0.99999998391923 GO:0020037 heme binding 2/1014 142/18639 0.0140845070422535 0.25889657471456 0.996820991107282 0.99999998391923 GO:0015078 proton transmembrane transporter activity 3/1014 185/18639 0.0162162162162162 0.298080921157844 0.997896222377288 0.99999998391923 GO:0046906 tetrapyrrole binding 2/1014 152/18639 0.0131578947368421 0.241863905325444 0.998076684026227 0.99999998391923 GO:0046873 metal ion transmembrane transporter activity 12/1014 450/18639 0.0266666666666667 0.490177514792899 0.998612296723709 0.99999998391923 GO:0001664 G protein-coupled receptor binding 6/1014 297/18639 0.0202020202020202 0.371346602115833 0.999077223376323 0.99999998391923 GO:0099094 ligand-gated monoatomic cation channel activity 1/1014 136/18639 0.00735294117647059 0.135159241211277 0.999517253915803 0.99999998391923 GO:0005216 monoatomic ion channel activity 10/1014 448/18639 0.0223214285714286 0.410304839391378 0.999778924912839 0.99999998391923 GO:0030371 translation repressor activity 5/1014 329/18639 0.0151975683890578 0.27935648639413 0.999939731778188 0.99999998391923 GO:0005244 voltage-gated monoatomic ion channel activity 1/1014 173/18639 0.00578034682080925 0.106252351472449 0.999940137360056 0.99999998391923 GO:0022832 voltage-gated channel activity 1/1014 175/18639 0.00571428571428571 0.105038038884193 0.999946531346804 0.99999998391923 GO:0005261 monoatomic cation channel activity 5/1014 341/18639 0.0146627565982405 0.269525759600201 0.999965070147556 0.99999998391923 GO:0015276 ligand-gated monoatomic ion channel activity 1/1014 186/18639 0.00537634408602151 0.0988261118534071 0.99997127962671 0.99999998391923 GO:0022834 ligand-gated channel activity 1/1014 188/18639 0.00531914893617021 0.0977747702379454 0.99997434937783 0.99999998391923 GO:0022836 gated channel activity 1/1014 318/18639 0.00314465408805031 0.0578039522161438 0.99999998391923 0.99999998391923