category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Organismal Systems	Immune system	hsa04612	Antigen processing and presentation	7/49	82/9376	16.3344947735192	HLA-C/HLA-DRB1/B2M/TAP1/HLA-F/HLA-A/HSPA5	10.1085241684423
Human Diseases	Infectious disease: viral	hsa05168	Herpes simplex virus 1 infection	9/49	180/9376	9.56734693877551	HLA-C/HLA-DRB1/B2M/TAP1/BST2/STAT1/HLA-F/HLA-A/CCL5	8.41193320099558
Human Diseases	Infectious disease: viral	hsa05170	Human immunodeficiency virus 1 infection	9/49	214/9376	8.04730116345604	HLA-C/B2M/RAC2/TAP1/BST2/CD3D/HLA-F/APOBEC3G/HLA-A	7.55870270226469
Human Diseases	Infectious disease: viral	hsa05166	Human T-cell leukemia virus 1 infection	9/49	224/9376	7.68804664723032	HLA-C/HLA-DRB1/B2M/IL2RA/ETS1/IL2RG/CD3D/HLA-F/HLA-A	7.34307538570171
Organismal Systems	Immune system	hsa04658	Th1 and Th2 cell differentiation	6/49	93/9376	12.3449637919684	HLA-DRB1/MAF/IL2RA/STAT1/IL2RG/CD3D	7.96917021374515
Human Diseases	Immune disease	hsa05320	Autoimmune thyroid disease	5/49	54/9376	17.7173091458806	HLA-C/HLA-DRB1/CTLA4/HLA-F/HLA-A	8.92938182868376
Human Diseases	Infectious disease: viral	hsa05169	Epstein-Barr virus infection	8/49	205/9376	7.46719761075162	HLA-C/HLA-DRB1/B2M/TAP1/STAT1/CD3D/HLA-F/HLA-A	6.78574296357284
Environmental Information Processing	Signaling molecules and interaction	hsa04514	Cell adhesion molecule (CAM) interaction	7/49	160/9376	8.37142857142857	HLA-C/PTPRC/CD2/HLA-DRB1/CTLA4/HLA-F/HLA-A	6.81636926793022
Organismal Systems	Immune system	hsa04659	Th17 cell differentiation	6/49	109/9376	10.5328590151657	HLA-DRB1/IL2RA/STAT1/IL2RG/CD3D/EBI3	7.25570350329965
Human Diseases	Cardiovascular disease	hsa05416	Viral myocarditis	5/49	70/9376	13.667638483965	HLA-C/HLA-DRB1/RAC2/HLA-F/HLA-A	7.7103811370167
Human Diseases	Immune disease	hsa05340	Primary immunodeficiency	4/49	38/9376	20.1417830290011	PTPRC/TAP1/IL2RG/CD3D	8.56958799425855
Human Diseases	Immune disease	hsa05330	Allograft rejection	4/49	39/9376	19.6253270538985	HLA-C/HLA-DRB1/HLA-F/HLA-A	8.44783108411839
Human Diseases	Endocrine and metabolic disease	hsa04940	Type I diabetes mellitus	4/49	44/9376	17.3951762523191	HLA-C/HLA-DRB1/HLA-F/HLA-A	7.90073968504851
Human Diseases	Neurodegenerative disease	hsa05020	Prion disease	8/49	275/9376	5.56645640074211	MT-CO2/MT-CO1/MT-CO3/CYBA/RAC2/HSPA5/MT-CYB/CCL5	5.57075161743224
Human Diseases	Immune disease	hsa05332	Graft-versus-host disease	4/49	45/9376	17.0086167800454	HLA-C/HLA-DRB1/HLA-F/HLA-A	7.80204876516583
Cellular Processes	Transport and catabolism	hsa04145	Phagosome	6/49	155/9376	7.40697827518104	HLA-C/HLA-DRB1/CYBA/TAP1/HLA-F/HLA-A	5.82965399857662
Human Diseases	Infectious disease: viral	hsa05163	Human cytomegalovirus infection	7/49	227/9376	5.90056639395846	HLA-C/B2M/RAC2/TAP1/HLA-F/HLA-A/CCL5	5.41732738561936
Environmental Information Processing	Signaling molecules and interaction	hsa04061	Viral protein interaction with cytokine and cytokine receptor	5/49	100/9376	9.56734693877551	TNFSF10/IL2RA/IL2RG/CXCL13/CCL5	6.24278925307379
Human Diseases	Immune disease	hsa05321	Inflammatory bowel disease	4/49	66/9376	11.5967841682127	HLA-DRB1/MAF/STAT1/IL2RG	6.2615796010676
Human Diseases	Cardiovascular disease	hsa05415	Diabetic cardiomyopathy	6/49	205/9376	5.60039820806371	MT-CO2/MT-CO1/MT-CO3/CYBA/RAC2/MT-CYB	4.82699333604767
Environmental Information Processing	Signaling molecules and interaction	hsa04060	Cytokine-cytokine receptor interaction	7/49	298/9376	4.49472674976031	TNFSF10/IL2RA/IL2RG/EBI3/IL32/CXCL13/CCL5	4.44364091495637
Organismal Systems	Circulatory system	hsa04260	Cardiac muscle contraction	4/49	87/9376	8.79756040347173	MT-CO2/MT-CO1/MT-CO3/MT-CYB	5.29598300038377
Cellular Processes	Cell growth and death	hsa04218	Cellular senescence	5/49	157/9376	6.0938515533602	HLA-C/ETS1/HLA-F/HLA-A/RBL2	4.66516375720768
Human Diseases	Immune disease	hsa05323	Rheumatoid arthritis	4/49	95/9376	8.05671321160043	HLA-DRB1/CTLA4/FLT1/CCL5	5.01048278112291
Organismal Systems	Immune system	hsa04640	Hematopoietic cell lineage	4/49	100/9376	7.65387755102041	CD2/HLA-DRB1/IL2RA/CD3D	4.84849692251591
Organismal Systems	Immune system	hsa04621	NOD-like receptor signaling pathway	5/49	187/9376	5.11622830950562	CYBA/STAT1/GBP5/CCL5/IFI16	4.12096401824956
Organismal Systems	Immune system	hsa04650	Natural killer cell mediated cytotoxicity	4/49	133/9376	5.75479515114316	HLA-C/TNFSF10/RAC2/HLA-A	4.00279957449387
Human Diseases	Infectious disease: viral	hsa05162	Measles	4/49	136/9376	5.62785114045618	IL2RA/STAT1/IL2RG/CD3D	3.94026598333511
Metabolism	Energy metabolism	hsa00190	Oxidative phosphorylation	4/49	138/9376	5.54628808044957	MT-CO2/MT-CO1/MT-CO3/MT-CYB	3.89960129442791
Human Diseases	Cancer: overview	hsa05208	Chemical carcinogenesis - reactive oxygen species	5/49	227/9376	4.2146902813989	MT-CO2/MT-CO1/MT-CO3/CYBA/MT-CYB	3.55367692174854
Human Diseases	Infectious disease: viral	hsa05165	Human papillomavirus infection	6/49	333/9376	3.44769259054973	HLA-C/FN1/STAT1/HLA-F/HLA-A/RBL2	3.29636591155347
Human Diseases	Infectious disease: parasitic	hsa05140	Leishmaniasis	3/49	78/9376	7.35949764521193	HLA-DRB1/CYBA/STAT1	4.0877848626418
Human Diseases	Endocrine and metabolic disease	hsa04932	Non-alcoholic fatty liver disease	4/49	157/9376	4.87508124268816	MT-CO2/MT-CO1/MT-CO3/MT-CYB	3.54896258366597
Cellular Processes	Transport and catabolism	hsa04144	Endocytosis	5/49	250/9376	3.8269387755102	HLA-C/IL2RA/IL2RG/HLA-F/HLA-A	3.28366515787734
Human Diseases	Neurodegenerative disease	hsa05014	Amyotrophic lateral sclerosis	6/49	368/9376	3.11978704525288	PFN1/MT-CO2/MT-CO1/MT-CO3/HSPA5/MT-CYB	3.00686994490725
Human Diseases	Immune disease	hsa05310	Asthma	2/49	32/9376	11.9591836734694	HLA-DRB1/PRG2	4.50090109640292
Human Diseases	Infectious disease: viral	hsa05164	Influenza A	4/49	173/9376	4.42420667689041	TNFSF10/HLA-DRB1/STAT1/CCL5	3.29481473950158
Human Diseases	Neurodegenerative disease	hsa05012	Parkinson disease	5/49	268/9376	3.56990557416997	MT-CO2/MT-CO1/MT-CO3/HSPA5/MT-CYB	3.09375374685518
Organismal Systems	Immune system	hsa04062	Chemokine signaling pathway	4/49	193/9376	3.96573966374114	RAC2/STAT1/CXCL13/CCL5	3.01739438364904
Human Diseases	Infectious disease: viral	hsa05167	Kaposi sarcoma-associated herpesvirus infection	4/49	196/9376	3.90503956684715	HLA-C/STAT1/HLA-F/HLA-A	2.97900640383314
Human Diseases	Cancer: overview	hsa05203	Viral carcinogenesis	4/49	205/9376	3.73359880537581	HLA-C/HLA-F/HLA-A/RBL2	2.86824370852249
Genetic Information Processing	Folding, sorting and degradation	hsa03050	Proteasome	2/49	46/9376	8.31943212067436	PSMB9/PSMB8	3.60685074663493
Environmental Information Processing	Signal transduction	hsa04015	Rap1 signaling pathway	4/49	212/9376	3.61031959953793	PFN1/RAC2/FLT1/SKAP1	2.78632495311354
Organismal Systems	Immune system	hsa04660	T cell receptor signaling pathway	3/49	122/9376	4.70525259284041	PTPRC/CTLA4/CD3D	2.98569662663483
Human Diseases	Cardiovascular disease	hsa05417	Lipid and atherosclerosis	4/49	216/9376	3.54346182917611	TNFSF10/CYBA/HSPA5/CCL5	2.74105060141682
Cellular Processes	Cell motility	hsa04810	Regulation of actin cytoskeleton	4/49	232/9376	3.2990851513019	PFN1/FN1/RAC2/RGCC	2.57006217625803
Organismal Systems	Environmental adaptation	hsa04714	Thermogenesis	4/49	235/9376	3.25696917064698	MT-CO2/MT-CO1/MT-CO3/MT-CYB	2.53965891520201
Organismal Systems	Development and regeneration	hsa04380	Osteoclast differentiation	3/49	142/9376	4.04254096004599	CYBA/STAT1/JUNB	2.64788037326641
Environmental Information Processing	Signal transduction	hsa04151	PI3K-Akt signaling pathway	5/49	362/9376	2.64291351899876	FN1/IL2RA/IL2RG/RBL2/FLT1	2.31059006437065
NA	NA	hsa04518	Integrin signaling	3/49	154/9376	3.72753776835409	FN1/RAC2/FLT1	2.47361020707295
Genetic Information Processing	Information processing in viruses	hsa03250	Viral life cycle - HIV-1	2/49	73/9376	5.24238188426055	BST2/APOBEC3G	2.63737793844784
Environmental Information Processing	Signal transduction	hsa04630	JAK-STAT signaling pathway	3/49	168/9376	3.41690962099125	IL2RA/STAT1/IL2RG	2.29110548948447
Human Diseases	Cancer: specific types	hsa05212	Pancreatic cancer	2/49	77/9376	4.97005035780546	RAC2/STAT1	2.53533845766647
Organismal Systems	Immune system	hsa04623	Cytosolic DNA-sensing pathway	2/49	83/9376	4.61076960904844	CCL5/IFI16	2.39482369160358
Human Diseases	Neurodegenerative disease	hsa05016	Huntington disease	4/49	308/9376	2.48502517890273	MT-CO2/MT-CO1/MT-CO3/MT-CYB	1.92072907089143
Human Diseases	Cancer: overview	hsa05235	PD-L1 expression and PD-1 checkpoint pathway in cancer	2/49	90/9376	4.25215419501134	STAT1/CD3D	2.24693616090637
Cellular Processes	Cellular community - eukaryotes	hsa04510	Focal adhesion	3/49	203/9376	2.82778727254449	FN1/RAC2/FLT1	1.90822974355225
Organismal Systems	Immune system	hsa04666	Fc gamma R-mediated phagocytosis	2/49	98/9376	3.90503956684715	PTPRC/RAC2	2.0953211438754
Human Diseases	Endocrine and metabolic disease	hsa04933	AGE-RAGE signaling pathway in diabetic complications	2/49	101/9376	3.78904829258436	FN1/STAT1	2.0425488488378
Metabolism	Lipid metabolism	hsa00100	Steroid biosynthesis	1/49	20/9376	9.56734693877551	LBR	2.77989847516831
Human Diseases	Infectious disease: parasitic	hsa05142	Chagas disease	2/49	103/9376	3.71547453933029	CD3D/CCL5	2.00847720647691
Human Diseases	Neurodegenerative disease	hsa05022	Pathways of neurodegeneration - multiple diseases	5/49	480/9376	1.99319727891156	MT-CO2/MT-CO1/MT-CO3/HSPA5/MT-CYB	1.61909168502969
Organismal Systems	Immune system	hsa04620	Toll-like receptor signaling pathway	2/49	109/9376	3.51095300505523	STAT1/CCL5	1.91115073520086
Human Diseases	Infectious disease: parasitic	hsa05145	Toxoplasmosis	2/49	112/9376	3.41690962099125	HLA-DRB1/STAT1	1.86501718740804
Organismal Systems	Immune system	hsa04670	Leukocyte transendothelial migration	2/49	116/9376	3.2990851513019	CYBA/RAC2	1.80588981090991
Environmental Information Processing	Signal transduction	hsa04014	Ras signaling pathway	3/49	238/9376	2.41193620305265	RAC2/ETS1/FLT1	1.59915538735213
Environmental Information Processing	Signal transduction	hsa04668	TNF signaling pathway	2/49	119/9376	3.21591493740353	JUNB/CCL5	1.76321033883025
Organismal Systems	Endocrine system	hsa04935	Growth hormone synthesis, secretion and action	2/49	122/9376	3.13683506189361	STAT1/JUNB	1.72186405005117
Human Diseases	Infectious disease: bacterial	hsa05132	Salmonella infection	3/49	248/9376	2.31468071099408	PFN1/TNFSF10/PTPRC	1.52079615397874
Human Diseases	Neurodegenerative disease	hsa05010	Alzheimer disease	4/49	388/9376	1.97264885335578	MT-CO2/MT-CO1/MT-CO3/MT-CYB	1.41825100471687
Genetic Information Processing	Folding, sorting and degradation	hsa03060	Protein export	1/49	31/9376	6.1724818959842	HSPA5	2.09075364775453
Environmental Information Processing	Signal transduction	hsa04068	FoxO signaling pathway	2/49	133/9376	2.87739757557158	TNFSF10/RBL2	1.58047738709564
Human Diseases	Infectious disease: bacterial	hsa05135	Yersinia infection	2/49	138/9376	2.77314404022479	FN1/RAC2	1.52092315139518
Human Diseases	Cardiovascular disease	hsa05418	Fluid shear stress and atherosclerosis	2/49	142/9376	2.69502730669733	CYBA/RAC2	1.4751582958103
Human Diseases	Cancer: specific types	hsa05219	Bladder cancer	1/49	41/9376	4.66699850671976	TYMP	1.70552539417459
Environmental Information Processing	Signal transduction	hsa04010	MAPK signaling pathway	3/49	300/9376	1.9134693877551	RAC2/PTPN7/FLT1	1.16552091546844
Organismal Systems	Excretory system	hsa04962	Vasopressin-regulated water reabsorption	1/49	44/9376	4.34879406307978	ARHGDIB	1.61376430140461
Environmental Information Processing	Membrane transport	hsa02010	ABC transporters	1/49	45/9376	4.25215419501134	TAP1	1.58498800801734
Cellular Processes	Cell growth and death	hsa04217	Necroptosis	2/49	168/9376	2.2779397473275	TNFSF10/STAT1	1.21142087602416
Organismal Systems	Immune system	hsa04672	Intestinal immune network for IgA production	1/49	50/9376	3.8269387755102	HLA-DRB1	1.45266806516465
Human Diseases	Infectious disease: bacterial	hsa05152	Tuberculosis	2/49	181/9376	2.11433081519901	HLA-DRB1/STAT1	1.09721124761209
Human Diseases	Infectious disease: bacterial	hsa05134	Legionellosis	1/49	56/9376	3.41690962099125	CLK1	1.31479837201614
Metabolism	Nucleotide metabolism	hsa00240	Pyrimidine metabolism	1/49	59/9376	3.24316845382221	TYMP	1.25274459215968
Environmental Information Processing	Signal transduction	hsa04370	VEGF signaling pathway	1/49	60/9376	3.1891156462585	RAC2	1.23294095836707
Organismal Systems	Immune system	hsa04613	Neutrophil extracellular trap formation	2/49	195/9376	1.96253270538985	CYBA/RAC2	0.984465490387324
Human Diseases	Cancer: overview	hsa05202	Transcriptional misregulation in cancer	2/49	201/9376	1.90394963955732	MAF/FLT1	0.938970434977341
Human Diseases	Cancer: overview	hsa05205	Proteoglycans in cancer	2/49	204/9376	1.87595038015206	FN1/TIMP3	0.916801374975471
Organismal Systems	Immune system	hsa04664	Fc epsilon RI signaling pathway	1/49	69/9376	2.77314404022479	RAC2	1.07146106683249
Human Diseases	Cancer: specific types	hsa05211	Renal cell carcinoma	1/49	70/9376	2.733527696793	ETS1	1.05514214593099
Organismal Systems	Endocrine system	hsa04917	Prolactin signaling pathway	1/49	71/9376	2.69502730669733	STAT1	1.03910724885522
Human Diseases	Infectious disease: bacterial	hsa05120	Epithelial cell signaling in Helicobacter pylori infection	1/49	71/9376	2.69502730669733	CCL5	1.03910724885522
Organismal Systems	Endocrine system	hsa04918	Thyroid hormone synthesis	1/49	75/9376	2.5512925170068	HSPA5	0.977624770456722
Human Diseases	Infectious disease: bacterial	hsa05100	Bacterial invasion of epithelial cells	1/49	78/9376	2.45316588173731	FN1	0.934072127339446
Cellular Processes	Cell motility	hsa04820	Cytoskeleton in muscle cells	2/49	233/9376	1.6424629937812	FN1/LBR	0.719771104244849
Metabolism	Xenobiotics biodegradation and metabolism	hsa00983	Drug metabolism - other enzymes	1/49	82/9376	2.33349925335988	TYMP	0.879044900420586
Metabolism	Global and overview maps	hsa01232	Nucleotide metabolism	1/49	85/9376	2.25114045618247	TYMP	0.83984084053086
Human Diseases	Cancer: specific types	hsa05210	Colorectal cancer	1/49	87/9376	2.19939010086793	RAC2	0.814607294635006
Environmental Information Processing	Signaling molecules and interaction	hsa04512	ECM-receptor interaction	1/49	89/9376	2.14996560421922	FN1	0.790050443239625
Organismal Systems	Immune system	hsa04662	B cell receptor signaling pathway	1/49	91/9376	2.10271361291769	RAC2	0.766134761595543
Human Diseases	Infectious disease: bacterial	hsa05131	Shigellosis	2/49	253/9376	1.51262402194079	PFN1/CCL5	0.599105169045043
Cellular Processes	Cellular community - eukaryotes	hsa04520	Adherens junction	1/49	93/9376	2.05749396532807	RAC2	0.742827351787034
Human Diseases	Cancer: specific types	hsa05222	Small cell lung cancer	1/49	93/9376	2.05749396532807	FN1	0.742827351787034
Human Diseases	Infectious disease: bacterial	hsa05150	Staphylococcus aureus infection	1/49	99/9376	1.93279736136879	HLA-DRB1	0.676260183091165
Human Diseases	Cancer: overview	hsa05231	Choline metabolism in cancer	1/49	99/9376	1.93279736136879	RAC2	0.676260183091165
Human Diseases	Infectious disease: parasitic	hsa05146	Amoebiasis	1/49	103/9376	1.85773726966515	FN1	0.634417937018502
Organismal Systems	Immune system	hsa04625	C-type lectin receptor signaling pathway	1/49	105/9376	1.822351797862	STAT1	0.614188520594907
Environmental Information Processing	Signal transduction	hsa04066	HIF-1 signaling pathway	1/49	110/9376	1.73951762523191	FLT1	0.565472401623966
Organismal Systems	Nervous system	hsa04722	Neurotrophin signaling pathway	1/49	120/9376	1.59455782312925	ARHGDIB	0.475100773813802
Organismal Systems	Endocrine system	hsa04919	Thyroid hormone signaling pathway	1/49	122/9376	1.56841753094681	STAT1	0.458031473467501
Environmental Information Processing	Signal transduction	hsa04071	Sphingolipid signaling pathway	1/49	125/9376	1.53077551020408	RAC2	0.432996346901493
Cellular Processes	Cell growth and death	hsa04210	Apoptosis	1/49	137/9376	1.39669298376285	TNFSF10	0.339011951542699
Human Diseases	Immune disease	hsa05322	Systemic lupus erythematosus	1/49	143/9376	1.33809048094762	HLA-DRB1	0.295285576534595
Human Diseases	Infectious disease: viral	hsa05160	Hepatitis C	1/49	156/9376	1.22658294086866	STAT1	0.206841051924099
Cellular Processes	Cell growth and death	hsa04110	Cell cycle	1/49	158/9376	1.21105657452855	RBL2	0.193919626775719
Human Diseases	Infectious disease: viral	hsa05161	Hepatitis B	1/49	163/9376	1.17390759984976	STAT1	0.162339617275162
Genetic Information Processing	Folding, sorting and degradation	hsa04141	Protein processing in endoplasmic reticulum	1/49	174/9376	1.09969505043397	HSPA5	0.0962099074584275
Environmental Information Processing	Signal transduction	hsa04310	Wnt signaling pathway	1/49	178/9376	1.07498280210961	RAC2	0.07320447904568
Organismal Systems	Development and regeneration	hsa04360	Axon guidance	1/49	184/9376	1.03992901508429	RAC2	0.0396465308078322
NA	NA	hsa04082	Neuroactive ligand signaling	1/49	199/9376	0.961542405907087	TAC3	-0.0397439450289328
Human Diseases	Infectious disease: bacterial	hsa05130	Pathogenic Escherichia coli infection	1/49	200/9376	0.956734693877551	TNFSF10	-0.0448271126092171
NA	NA	hsa04382	Cornified envelope formation	1/49	217/9376	0.881783127997743	S100A4	-0.127702085876846
Environmental Information Processing	Signal transduction	hsa04024	cAMP signaling pathway	1/49	226/9376	0.846667870688098	RAC2	-0.169117881271339
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	1/49	238/9376	0.803978734350883	STAT1	-0.222013191757985
Environmental Information Processing	Signal transduction	hsa04020	Calcium signaling pathway	1/49	254/9376	0.753334404627993	FLT1	-0.288863781995318
NA	NA	hsa04517	IgSF CAM signaling	1/49	299/9376	0.63995631697495	CD2	-0.458598164202424
Human Diseases	Cancer: overview	hsa05206	MicroRNAs in cancer	1/49	323/9376	0.592405383205914	TIMP3	-0.540313887680044
Environmental Information Processing	Signaling molecules and interaction	hsa04080	Neuroactive ligand-receptor interaction	1/49	370/9376	0.51715388858246	TAC3	-0.686841169028804
NA	NA	hsa04519	Cadherin signaling	1/49	404/9376	0.473631036573045	RAC2	-0.783878970827831