category subcategory ID Description GeneRatio BgRatio FoldEnrichment geneName zScore Human Diseases Infectious disease: parasitic hsa05143 African trypanosomiasis 3/18 37/9376 42.2342342342342 HBA1/HBA2/HBB 11.0214561802411 Human Diseases Infectious disease: parasitic hsa05144 Malaria 3/18 50/9376 31.2533333333333 HBA1/HBA2/HBB 9.40677810031064 Cellular Processes Transport and catabolism hsa04145 Phagosome 3/18 155/9376 10.0817204301075 HLA-C/CTSL/CYBA 5.00006139416115 Cellular Processes Cell growth and death hsa04218 Cellular senescence 3/18 157/9376 9.95329087048832 HLA-C/IGFBP3/SERPINE1 4.96159124921027 Human Diseases Cancer: overview hsa05205 Proteoglycans in cancer 3/18 204/9376 7.66013071895425 TIMP3/FN1/CTSL 4.21789907864501 Cellular Processes Cell growth and death hsa04115 p53 signaling pathway 2/18 75/9376 13.8903703703704 IGFBP3/SERPINE1 4.91543067802737 Organismal Systems Immune system hsa04612 Antigen processing and presentation 2/18 82/9376 12.7046070460705 HLA-C/CTSL 4.6686659468467 Human Diseases Endocrine and metabolic disease hsa04933 AGE-RAGE signaling pathway in diabetic complications 2/18 101/9376 10.3146314631463 FN1/SERPINE1 4.12762063203557 Human Diseases Cardiovascular disease hsa05418 Fluid shear stress and atherosclerosis 2/18 142/9376 7.33646322378717 CTSL/CYBA 3.3367719498943 NA NA hsa04382 Cornified envelope formation 2/18 217/9376 4.80081925243216 KRT7/KRT19 2.48435368937941 Cellular Processes Cell motility hsa04810 Regulation of actin cytoskeleton 2/18 232/9376 4.4904214559387 FN1/PFN1 2.36093550682276 Human Diseases Immune disease hsa05330 Allograft rejection 1/18 39/9376 13.3561253561254 HLA-C 3.39110549125328 Human Diseases Cancer: specific types hsa05219 Bladder cancer 1/18 41/9376 12.7046070460705 TYMP 3.29398771730061 Human Diseases Endocrine and metabolic disease hsa04940 Type I diabetes mellitus 1/18 44/9376 11.8383838383838 HLA-C 3.1603404575897 Human Diseases Immune disease hsa05332 Graft-versus-host disease 1/18 45/9376 11.5753086419753 HLA-C 3.11864243277934 Human Diseases Immune disease hsa05320 Autoimmune thyroid disease 1/18 54/9376 9.64609053497942 HLA-C 2.79442513983228 Metabolism Nucleotide metabolism hsa00240 Pyrimidine metabolism 1/18 59/9376 8.8286252354049 TYMP 2.64547603592775 Human Diseases Cardiovascular disease hsa05416 Viral myocarditis 1/18 70/9376 7.44126984126984 HLA-C 2.37229863780364 Human Diseases Infectious disease: viral hsa05165 Human papillomavirus infection 2/18 333/9376 3.12846179512846 FN1/HLA-C 1.73445118278887 Human Diseases Infectious disease: bacterial hsa05100 Bacterial invasion of epithelial cells 1/18 78/9376 6.67806267806268 FN1 2.20842717716388 Human Diseases Infectious disease: parasitic hsa05140 Leishmaniasis 1/18 78/9376 6.67806267806268 CYBA 2.20842717716388 Metabolism Xenobiotics biodegradation and metabolism hsa00983 Drug metabolism - other enzymes 1/18 82/9376 6.35230352303523 TYMP 2.13489586594634 Metabolism Global and overview maps hsa01232 Nucleotide metabolism 1/18 85/9376 6.1281045751634 TYMP 2.08288588114483 Organismal Systems Immune system hsa04610 Complement and coagulation cascades 1/18 88/9376 5.91919191919192 SERPINE1 2.03331361953306 Environmental Information Processing Signaling molecules and interaction hsa04512 ECM-receptor interaction 1/18 89/9376 5.85268414481898 FN1 2.01729622312989 Human Diseases Cancer: specific types hsa05222 Small cell lung cancer 1/18 93/9376 5.60095579450418 FN1 1.95558064382914 Human Diseases Immune disease hsa05323 Rheumatoid arthritis 1/18 95/9376 5.48304093567251 CTSL 1.92604970728228 Human Diseases Infectious disease: bacterial hsa05150 Staphylococcus aureus infection 1/18 99/9376 5.26150392817059 KRT19 1.86942085119753 Human Diseases Infectious disease: parasitic hsa05142 Chagas disease 1/18 103/9376 5.0571736785329 SERPINE1 1.81577675485457 Human Diseases Infectious disease: parasitic hsa05146 Amoebiasis 1/18 103/9376 5.0571736785329 FN1 1.81577675485457 NA NA hsa04519 Cadherin signaling 2/18 404/9376 2.57865786578658 KRT7/KRT19 1.422539840249 Organismal Systems Immune system hsa04659 Th17 cell differentiation 1/18 109/9376 4.77879714576962 EBI3 1.74031401017258 Environmental Information Processing Signal transduction hsa04066 HIF-1 signaling pathway 1/18 110/9376 4.73535353535354 SERPINE1 1.728272729294 Environmental Information Processing Signal transduction hsa04350 TGF-beta signaling pathway 1/18 110/9376 4.73535353535354 ID3 1.728272729294 Organismal Systems Immune system hsa04670 Leukocyte transendothelial migration 1/18 116/9376 4.4904214559387 CYBA 1.65894405799721 Organismal Systems Endocrine system hsa04935 Growth hormone synthesis, secretion and action 1/18 122/9376 4.2695810564663 IGFBP3 1.59418106530265 Organismal Systems Immune system hsa04650 Natural killer cell mediated cytotoxicity 1/18 133/9376 3.91645781119465 HLA-C 1.48561204770552 Cellular Processes Cell growth and death hsa04210 Apoptosis 1/18 137/9376 3.80210867802109 CTSL 1.44898251709726 Human Diseases Infectious disease: bacterial hsa05135 Yersinia infection 1/18 138/9376 3.77455716586151 FN1 1.44004018627234 Organismal Systems Endocrine system hsa04915 Estrogen signaling pathway 1/18 139/9376 3.74740207833733 KRT19 1.4311808651183 Environmental Information Processing Signal transduction hsa04371 Apelin signaling pathway 1/18 140/9376 3.72063492063492 SERPINE1 1.42240311323363 Organismal Systems Development and regeneration hsa04380 Osteoclast differentiation 1/18 142/9376 3.66823161189358 CYBA 1.40508673118542 Cellular Processes Cellular community - eukaryotes hsa04550 Signaling pathways regulating pluripotency of stem cells 1/18 144/9376 3.61728395061728 ID3 1.38808020371 NA NA hsa04518 Integrin signaling 1/18 154/9376 3.38239538239538 FN1 1.30735041911763 Environmental Information Processing Signal transduction hsa04390 Hippo signaling pathway 1/18 157/9376 3.31776362349611 SERPINE1 1.28442110040026 Environmental Information Processing Signaling molecules and interaction hsa04514 Cell adhesion molecule (CAM) interaction 1/18 160/9376 3.25555555555556 HLA-C 1.26203865488959 Cellular Processes Transport and catabolism hsa04140 Autophagy - animal 1/18 169/9376 3.08218277449047 CTSL 1.19793567997821 Genetic Information Processing Folding, sorting and degradation hsa04141 Protein processing in endoplasmic reticulum 1/18 174/9376 2.99361430395913 PDIA6 1.16413948828795 Human Diseases Infectious disease: viral hsa05168 Herpes simplex virus 1 infection 1/18 180/9376 2.89382716049383 HLA-C 1.12514237749122 Organismal Systems Immune system hsa04621 NOD-like receptor signaling pathway 1/18 187/9376 2.78550207961973 CYBA 1.08162672212672 Organismal Systems Immune system hsa04613 Neutrophil extracellular trap formation 1/18 195/9376 2.67122507122507 CYBA 1.03427880383172 Human Diseases Infectious disease: viral hsa05167 Kaposi sarcoma-associated herpesvirus infection 1/18 196/9376 2.65759637188209 HLA-C 1.02852736942216 NA NA hsa04082 Neuroactive ligand signaling 1/18 199/9376 2.61753210496929 TAC3 1.011485012402 Human Diseases Cancer: overview hsa05202 Transcriptional misregulation in cancer 1/18 201/9376 2.59148700939746 IGFBP3 1.00029583518994 Cellular Processes Cellular community - eukaryotes hsa04510 Focal adhesion 1/18 203/9376 2.56595511767926 FN1 0.989240761248524 Human Diseases Infectious disease: viral hsa05169 Epstein-Barr virus infection 1/18 205/9376 2.54092140921409 HLA-C 0.978316646541421 Human Diseases Cancer: overview hsa05203 Viral carcinogenesis 1/18 205/9376 2.54092140921409 HLA-C 0.978316646541421 Human Diseases Cardiovascular disease hsa05415 Diabetic cardiomyopathy 1/18 205/9376 2.54092140921409 CYBA 0.978316646541421 Environmental Information Processing Signal transduction hsa04015 Rap1 signaling pathway 1/18 212/9376 2.45702306079665 PFN1 0.941070557203592 Human Diseases Infectious disease: viral hsa05170 Human immunodeficiency virus 1 infection 1/18 214/9376 2.43406022845275 HLA-C 0.93069955172243 Human Diseases Cardiovascular disease hsa05417 Lipid and atherosclerosis 1/18 216/9376 2.41152263374486 CYBA 0.92044396700136 Human Diseases Infectious disease: viral hsa05166 Human T-cell leukemia virus 1 infection 1/18 224/9376 2.32539682539683 HLA-C 0.880526234257163 Human Diseases Infectious disease: viral hsa05163 Human cytomegalovirus infection 1/18 227/9376 2.29466470876162 HLA-C 0.865991830150996 Human Diseases Cancer: overview hsa05208 Chemical carcinogenesis - reactive oxygen species 1/18 227/9376 2.29466470876162 CYBA 0.865991830150996 Cellular Processes Cell motility hsa04820 Cytoskeleton in muscle cells 1/18 233/9376 2.23557463042442 FN1 0.837592834731983 Human Diseases Infectious disease: bacterial hsa05132 Salmonella infection 1/18 248/9376 2.10035842293907 PFN1 0.77019832045211 Cellular Processes Transport and catabolism hsa04142 Lysosome biogenesis 1/18 250/9376 2.08355555555556 CTSL 0.761572626447459 Cellular Processes Transport and catabolism hsa04144 Endocytosis 1/18 250/9376 2.08355555555556 HLA-C 0.761572626447459 Human Diseases Infectious disease: bacterial hsa05131 Shigellosis 1/18 253/9376 2.05884936319719 PFN1 0.748782995530279 Human Diseases Neurodegenerative disease hsa05020 Prion disease 1/18 275/9376 1.89414141414141 CYBA 0.660021937582415 Environmental Information Processing Signaling molecules and interaction hsa04060 Cytokine-cytokine receptor interaction 1/18 298/9376 1.74794929157345 EBI3 0.575460565731139 Human Diseases Cancer: overview hsa05206 MicroRNAs in cancer 1/18 323/9376 1.61265909872721 TIMP3 0.491421619694135 Environmental Information Processing Signal transduction hsa04151 PI3K-Akt signaling pathway 1/18 362/9376 1.43891958256599 FN1 0.373517398574229 Human Diseases Neurodegenerative disease hsa05014 Amyotrophic lateral sclerosis 1/18 368/9376 1.41545893719807 PFN1 0.356589209122863 Environmental Information Processing Signaling molecules and interaction hsa04080 Neuroactive ligand-receptor interaction 1/18 370/9376 1.40780780780781 TAC3 0.351011057271951