category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Human Diseases	Infectious disease: parasitic	hsa05143	African trypanosomiasis	3/36	37/9376	21.1171171171171	HBB/HBA2/HBA1	7.61166855711673
Human Diseases	Infectious disease: parasitic	hsa05144	Malaria	3/36	50/9376	15.6266666666667	HBB/HBA2/HBA1	6.43792793940678
Human Diseases	Cardiovascular disease	hsa05418	Fluid shear stress and atherosclerosis	4/36	142/9376	7.33646322378717	ACTB/CTSL/SQSTM1/DUSP1	4.72345308515873
Human Diseases	Neurodegenerative disease	hsa05014	Amyotrophic lateral sclerosis	6/36	368/9376	4.2463768115942	PFN1/ACTB/CYC1/COX5A/SQSTM1/XBP1	3.94431960886839
Human Diseases	Infectious disease: bacterial	hsa05100	Bacterial invasion of epithelial cells	3/36	78/9376	10.017094017094	CLTB/ACTB/CLTA	4.9645807476353
Cellular Processes	Cell growth and death	hsa04216	Ferroptosis	2/36	42/9376	12.4021164021164	FTH1/FTL	4.59768981126698
Metabolism	Metabolism of cofactors and vitamins	hsa00860	Porphyrin metabolism	2/36	46/9376	11.3236714975845	FTH1/FTL	4.35748319751897
Cellular Processes	Transport and catabolism	hsa04142	Lysosome biogenesis	4/36	250/9376	4.16711111111111	CLTB/CTSL/LAPTM4A/CLTA	3.15105890980505
Cellular Processes	Transport and catabolism	hsa04144	Endocytosis	4/36	250/9376	4.16711111111111	CLTB/SNX3/CLTA/ARF4	3.15105890980505
Organismal Systems	Endocrine system	hsa04915	Estrogen signaling pathway	3/36	139/9376	5.621103117506	KRT10/POMC/KRT19	3.40761905785358
Human Diseases	Infectious disease: bacterial	hsa05110	Vibrio cholerae infection	2/36	51/9376	10.2135076252723	ACTB/KDELR2	4.09589785857121
Organismal Systems	Excretory system	hsa04961	Endocrine and other factor-regulated calcium reabsorption	2/36	53/9376	9.82809224318658	CLTB/CLTA	4.00120133963531
Human Diseases	Neurodegenerative disease	hsa05012	Parkinson disease	4/36	268/9376	3.88723051409619	CYC1/COX5A/XBP1/DUSP1	2.97715054089257
Human Diseases	Endocrine and metabolic disease	hsa04932	Non-alcoholic fatty liver disease	3/36	157/9376	4.97664543524416	CYC1/COX5A/XBP1	3.11952334071582
Organismal Systems	Digestive system	hsa04978	Mineral absorption	2/36	61/9376	8.53916211293261	FTH1/FTL	3.66741469057395
Cellular Processes	Cell growth and death	hsa04217	Necroptosis	3/36	168/9376	4.65079365079365	FTH1/FTL/SQSTM1	2.96430388080914
Human Diseases	Neurodegenerative disease	hsa05016	Huntington disease	4/36	308/9376	3.38239538239538	CLTB/CYC1/COX5A/CLTA	2.6393494317939
Organismal Systems	Nervous system	hsa04721	Synaptic vesicle cycle	2/36	79/9376	6.59353023909986	CLTB/CLTA	3.09949950186734
Human Diseases	Cancer: overview	hsa05205	Proteoglycans in cancer	3/36	204/9376	3.83006535947712	TIMP3/ACTB/CTSL	2.53713149602138
Organismal Systems	Circulatory system	hsa04260	Cardiac muscle contraction	2/36	87/9376	5.98722860791826	CYC1/COX5A	2.90133496245263
Genetic Information Processing	Translation	hsa03010	Ribosome	3/36	222/9376	3.51951951951952	RPL13/MRPL23/RPL7	2.35858868624346
Human Diseases	Infectious disease: bacterial	hsa05150	Staphylococcus aureus infection	2/36	99/9376	5.26150392817059	KRT10/KRT19	2.64630661598817
Human Diseases	Infectious disease: parasitic	hsa05146	Amoebiasis	2/36	103/9376	5.0571736785329	HSPB1/PRDX1	2.57036934002906
Metabolism	Amino acid metabolism	hsa00360	Phenylalanine metabolism	1/36	16/9376	16.2777777777778	MIF	3.79704466794569
Organismal Systems	Environmental adaptation	hsa04714	Thermogenesis	3/36	235/9376	3.32482269503546	ACTB/CYC1/COX5A	2.24073430798705
Organismal Systems	Digestive system	hsa04980	Cobalamin transport and metabolism	1/36	18/9376	14.4691358024691	PRDX1	3.5509774493417
Human Diseases	Infectious disease: bacterial	hsa05131	Shigellosis	3/36	253/9376	3.08827404479578	PFN1/ACTB/SQSTM1	2.09046241801494
Cellular Processes	Cell growth and death	hsa04210	Apoptosis	2/36	137/9376	3.80210867802109	ACTB/CTSL	2.05114435253537
Metabolism	Energy metabolism	hsa00190	Oxidative phosphorylation	2/36	138/9376	3.77455716586151	CYC1/COX5A	2.03848580686376
Human Diseases	Neurodegenerative disease	hsa05022	Pathways of neurodegeneration - multiple diseases	4/36	480/9376	2.17037037037037	CYC1/COX5A/SQSTM1/XBP1	1.63421804062458
Cellular Processes	Transport and catabolism	hsa04145	Phagosome	2/36	155/9376	3.36057347670251	ACTB/CTSL	1.83974576402152
Metabolism	Amino acid metabolism	hsa00350	Tyrosine metabolism	1/36	37/9376	7.03903903903904	MIF	2.28497767851347
Cellular Processes	Transport and catabolism	hsa04140	Autophagy - animal	2/36	169/9376	3.08218277449047	CTSL/SQSTM1	1.69576856566241
Human Diseases	Cancer: specific types	hsa05219	Bladder cancer	1/36	41/9376	6.35230352303523	TYMP	2.13225406722336
Organismal Systems	Digestive system	hsa04979	Cholesterol metabolism	1/36	52/9376	5.00854700854701	VAPA	1.7994963530657
Human Diseases	Neurodegenerative disease	hsa05010	Alzheimer disease	3/36	388/9376	2.01374570446735	CYC1/COX5A/XBP1	1.26612565374918
Human Diseases	Cardiovascular disease	hsa05415	Diabetic cardiomyopathy	2/36	205/9376	2.54092140921409	CYC1/COX5A	1.38488121206923
Environmental Information Processing	Signal transduction	hsa04015	Rap1 signaling pathway	2/36	212/9376	2.45702306079665	PFN1/ACTB	1.33215655535469
NA	NA	hsa04519	Cadherin signaling	3/36	404/9376	1.93399339933993	ACTB/KRT10/KRT19	1.1913882363149
NA	NA	hsa04382	Cornified envelope formation	2/36	217/9376	2.40040962621608	KRT10/KRT19	1.29575942142781
Metabolism	Nucleotide metabolism	hsa00240	Pyrimidine metabolism	1/36	59/9376	4.41431261770245	TYMP	1.63325761429091
Environmental Information Processing	Signal transduction	hsa04370	VEGF signaling pathway	1/36	60/9376	4.34074074074074	HSPB1	1.61163655371695
Human Diseases	Cancer: overview	hsa05208	Chemical carcinogenesis - reactive oxygen species	2/36	227/9376	2.29466470876162	CYC1/COX5A	1.22587693833213
Organismal Systems	Endocrine system	hsa04927	Cortisol synthesis and secretion	1/36	65/9376	4.00683760683761	POMC	1.51019121241035
Cellular Processes	Cell motility	hsa04810	Regulation of actin cytoskeleton	2/36	232/9376	2.24521072796935	PFN1/ACTB	1.19229078630943
Cellular Processes	Cell motility	hsa04820	Cytoskeleton in muscle cells	2/36	233/9376	2.23557463042442	ACTB/BGN	1.18567601224499
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	2/36	238/9376	2.18860877684407	RPL13/RPL7	1.15309552035907
Organismal Systems	Endocrine system	hsa04920	Adipocytokine signaling pathway	1/36	70/9376	3.72063492063492	POMC	1.41840813859346
Human Diseases	Cardiovascular disease	hsa05416	Viral myocarditis	1/36	70/9376	3.72063492063492	ACTB	1.41840813859346
Human Diseases	Infectious disease: bacterial	hsa05132	Salmonella infection	2/36	248/9376	2.10035842293907	PFN1/ACTB	1.09027397962837
Organismal Systems	Endocrine system	hsa04918	Thyroid hormone synthesis	1/36	75/9376	3.47259259259259	TTR	1.33469435553117
Organismal Systems	Digestive system	hsa04971	Gastric acid secretion	1/36	76/9376	3.42690058479532	ACTB	1.31880552726197
Human Diseases	Cancer: specific types	hsa05212	Pancreatic cancer	1/36	77/9376	3.38239538239538	RALBP1	1.30318036502664
Metabolism	Xenobiotics biodegradation and metabolism	hsa00983	Drug metabolism - other enzymes	1/36	82/9376	3.17615176151762	TYMP	1.22873497895799
Organismal Systems	Immune system	hsa04612	Antigen processing and presentation	1/36	82/9376	3.17615176151762	CTSL	1.22873497895799
Cellular Processes	Transport and catabolism	hsa04146	Peroxisome	1/36	83/9376	3.13788487282463	PRDX1	1.21453166580126
Metabolism	Global and overview maps	hsa01232	Nucleotide metabolism	1/36	85/9376	3.0640522875817	TYMP	1.1867585742288
Human Diseases	Cardiovascular disease	hsa05412	Arrhythmogenic right ventricular cardiomyopathy	1/36	86/9376	3.02842377260982	ACTB	1.17317692090779
Human Diseases	Neurodegenerative disease	hsa05020	Prion disease	2/36	275/9376	1.89414141414141	CYC1/COX5A	0.934310976045234
Organismal Systems	Immune system	hsa04610	Complement and coagulation cascades	1/36	88/9376	2.95959595959596	SERPINB2	1.14659546179227
Cellular Processes	Cellular community - eukaryotes	hsa04520	Adherens junction	1/36	93/9376	2.80047789725209	ACTB	1.08329950285231
Human Diseases	Immune disease	hsa05323	Rheumatoid arthritis	1/36	95/9376	2.74152046783626	CTSL	1.05914751061639
Organismal Systems	Endocrine system	hsa04925	Aldosterone synthesis and secretion	1/36	98/9376	2.65759637188209	POMC	1.02406634035145
Human Diseases	Cardiovascular disease	hsa05410	Hypertrophic cardiomyopathy	1/36	99/9376	2.6307519640853	ACTB	1.01266355360306
Environmental Information Processing	Signal transduction	hsa04010	MAPK signaling pathway	2/36	300/9376	1.7362962962963	HSPB1/DUSP1	0.804691567165027
Organismal Systems	Endocrine system	hsa04916	Melanogenesis	1/36	101/9376	2.57865786578658	POMC	0.990273588248922
Cellular Processes	Transport and catabolism	hsa04137	Mitophagy - animal	1/36	105/9376	2.48042328042328	SQSTM1	0.947067024666948
Human Diseases	Cardiovascular disease	hsa05414	Dilated cardiomyopathy	1/36	105/9376	2.48042328042328	ACTB	0.947067024666948
Organismal Systems	Endocrine system	hsa04922	Glucagon signaling pathway	1/36	107/9376	2.43406022845275	PPP4C	0.926203226771206
Organismal Systems	Nervous system	hsa04726	Serotonergic synapse	1/36	115/9376	2.26473429951691	DUSP1	0.847193715102118
Organismal Systems	Immune system	hsa04670	Leukocyte transendothelial migration	1/36	116/9376	2.24521072796935	ACTB	0.837779646939483
Genetic Information Processing	Chromosome	hsa03082	ATP-dependent chromatin remodeling	1/36	117/9376	2.22602089268756	ACTB	0.828461270219553
Organismal Systems	Endocrine system	hsa04919	Thyroid hormone signaling pathway	1/36	122/9376	2.13479052823315	ACTB	0.783239029169927
Organismal Systems	Immune system	hsa04611	Platelet activation	1/36	126/9376	2.06701940035273	ACTB	0.748600602678128
Human Diseases	Infectious disease: bacterial	hsa05135	Yersinia infection	1/36	138/9376	1.88727858293076	ACTB	0.65188954125475
Organismal Systems	Development and regeneration	hsa04380	Osteoclast differentiation	1/36	142/9376	1.83411580594679	SQSTM1	0.621783278436553
Human Diseases	Neurodegenerative disease	hsa05017	Spinocerebellar ataxia	1/36	144/9376	1.80864197530864	XBP1	0.607090000698822
NA	NA	hsa04518	Integrin signaling	1/36	154/9376	1.69119769119769	ACTB	0.536924882473679
Organismal Systems	Endocrine system	hsa04921	Oxytocin signaling pathway	1/36	154/9376	1.69119769119769	ACTB	0.536924882473679
Human Diseases	Endocrine and metabolic disease	hsa04934	Cushing syndrome	1/36	155/9376	1.68028673835125	POMC	0.530190929260985
Cellular Processes	Cell growth and death	hsa04218	Cellular senescence	1/36	157/9376	1.65888181174805	SQSTM1	0.516867099164697
Environmental Information Processing	Signal transduction	hsa04390	Hippo signaling pathway	1/36	157/9376	1.65888181174805	ACTB	0.516867099164697
Cellular Processes	Cellular community - eukaryotes	hsa04530	Tight junction	1/36	170/9376	1.53202614379085	ACTB	0.434595674946782
Human Diseases	Cancer: specific types	hsa05225	Hepatocellular carcinoma	1/36	170/9376	1.53202614379085	ACTB	0.434595674946782
Human Diseases	Infectious disease: viral	hsa05164	Influenza A	1/36	173/9376	1.50545921644188	ACTB	0.416589107970435
Genetic Information Processing	Folding, sorting and degradation	hsa04141	Protein processing in endoplasmic reticulum	1/36	174/9376	1.49680715197957	XBP1	0.410662266179215
Cellular Processes	Cell motility	hsa04814	Motor proteins	1/36	194/9376	1.34249713631157	ACTB	0.299262717873989
Organismal Systems	Immune system	hsa04613	Neutrophil extracellular trap formation	1/36	195/9376	1.33561253561254	ACTB	0.294018011768177
NA	NA	hsa04082	Neuroactive ligand signaling	1/36	199/9376	1.30876605248465	POMC	0.27331858790129
Human Diseases	Infectious disease: bacterial	hsa05130	Pathogenic Escherichia coli infection	1/36	200/9376	1.30222222222222	ACTB	0.268211960380584
Cellular Processes	Cellular community - eukaryotes	hsa04510	Focal adhesion	1/36	203/9376	1.28297755883963	ACTB	0.253050831335005
Human Diseases	Cardiovascular disease	hsa05417	Lipid and atherosclerosis	1/36	216/9376	1.20576131687243	XBP1	0.189935576785545
NA	NA	hsa04081	Hormone signaling	1/36	219/9376	1.18924403855911	POMC	0.175926437490969
Environmental Information Processing	Signal transduction	hsa04024	cAMP signaling pathway	1/36	226/9376	1.15240904621436	POMC	0.143985204733352
Environmental Information Processing	Signal transduction	hsa04014	Ras signaling pathway	1/36	238/9376	1.09430438842204	RALBP1	0.0914867616310027
NA	NA	hsa04517	IgSF CAM signaling	1/36	299/9376	0.871051653660349	ACTB	-0.140683658580692
Human Diseases	Cancer: overview	hsa05206	MicroRNAs in cancer	1/36	323/9376	0.806329549363605	TIMP3	-0.219903334349575
Environmental Information Processing	Signaling molecules and interaction	hsa04080	Neuroactive ligand-receptor interaction	1/36	370/9376	0.703903903903904	POMC	-0.360770503585449