category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Cellular Processes	Transport and catabolism	hsa04145	Phagosome	16/76	155/9376	12.73480475382	HLA-DRA/HLA-DRB1/HLA-B/HLA-A/HLA-DPA1/ACTB/HLA-DPB1/FCGR3A/CTSS/ITGB2/OLR1/HLA-DQA1/CYBB/HLA-C/CYBA/TUBA1B	13.3169161816053
Human Diseases	Infectious disease: parasitic	hsa05140	Leishmaniasis	12/76	78/9376	18.9797570850202	HLA-DRA/HLA-DRB1/NFKBIA/HLA-DPA1/HLA-DPB1/FCGR3A/ITGB2/HLA-DQA1/CYBB/IL1B/CYBA/JUN	14.4140926876974
Organismal Systems	Immune system	hsa04612	Antigen processing and presentation	12/76	82/9376	18.0539152759949	CD74/HLA-DRA/HLA-DRB1/HLA-B/HLA-A/HLA-DPA1/HLA-DPB1/CTSS/IFI30/HLA-DQA1/CTSB/HLA-C	14.0210537199609
Human Diseases	Endocrine and metabolic disease	hsa04940	Type I diabetes mellitus	9/76	44/9376	25.2344497607656	HLA-DRA/HLA-DRB1/HLA-B/HLA-A/HLA-DPA1/HLA-DPB1/HLA-DQA1/HLA-C/IL1B	14.5654228380915
Human Diseases	Immune disease	hsa05332	Graft-versus-host disease	9/76	45/9376	24.6736842105263	HLA-DRA/HLA-DRB1/HLA-B/HLA-A/HLA-DPA1/HLA-DPB1/HLA-DQA1/HLA-C/IL1B	14.3899396444294
Human Diseases	Cardiovascular disease	hsa05416	Viral myocarditis	10/76	70/9376	17.6240601503759	HLA-DRA/HLA-DRB1/HLA-B/HLA-A/HLA-DPA1/ACTB/HLA-DPB1/ITGB2/HLA-DQA1/HLA-C	12.6198896554529
Human Diseases	Neurodegenerative disease	hsa05020	Prion disease	16/76	275/9376	7.1777990430622	MT-ND3/MT-CO3/MT-ATP6/MT-CO2/MT-CYB/MT-ND1/C1QA/MT-ND2/C1QB/MT-CO1/MT-ND4/CYBB/IL1B/CYBA/TUBA1B/C1QC	9.39953840926677
Human Diseases	Immune disease	hsa05330	Allograft rejection	8/76	39/9376	25.306342780027	HLA-DRA/HLA-DRB1/HLA-B/HLA-A/HLA-DPA1/HLA-DPB1/HLA-DQA1/HLA-C	13.7498893231623
Human Diseases	Immune disease	hsa05323	Rheumatoid arthritis	10/76	95/9376	12.9861495844875	HLA-DRA/HLA-DRB1/HLA-DPA1/HLA-DPB1/ITGB2/CCL3/HLA-DQA1/IL1B/CXCL2/JUN	10.6143907083258
Human Diseases	Infectious disease: bacterial	hsa05150	Staphylococcus aureus infection	10/76	99/9376	12.461456671983	HLA-DRA/HLA-DRB1/HLA-DPA1/C1QA/HLA-DPB1/C1QB/FCGR3A/ITGB2/HLA-DQA1/C1QC	10.3634557176323
Human Diseases	Immune disease	hsa05320	Autoimmune thyroid disease	8/76	54/9376	18.2768031189084	HLA-DRA/HLA-DRB1/HLA-B/HLA-A/HLA-DPA1/HLA-DPB1/HLA-DQA1/HLA-C	11.5095057670842
Human Diseases	Infectious disease: viral	hsa05168	Herpes simplex virus 1 infection	12/76	180/9376	8.22456140350877	CD74/HLA-DRA/HLA-DRB1/HLA-B/HLA-A/NFKBIA/HLA-DPA1/HLA-DPB1/HLA-DQA1/HLA-C/IL1B/BIRC3	8.84706499696482
Human Diseases	Infectious disease: bacterial	hsa05152	Tuberculosis	12/76	181/9376	8.17912183774353	CD74/HLA-DRA/HLA-DRB1/CTSD/HLA-DPA1/HLA-DPB1/FCGR3A/CTSS/ITGB2/FCER1G/HLA-DQA1/IL1B	8.81628669705002
Human Diseases	Cancer: overview	hsa05208	Chemical carcinogenesis - reactive oxygen species	13/76	227/9376	7.06515186645027	MT-ND3/MT-CO3/MT-ATP6/MT-CO2/MT-CYB/NFKBIA/MT-ND1/MT-ND2/MT-CO1/SOD2/MT-ND4/CYBA/JUN	8.36216542165788
Human Diseases	Infectious disease: viral	hsa05169	Epstein-Barr virus infection	12/76	205/9376	7.22156611039795	HLA-DRA/HLA-DRB1/HLA-B/HLA-A/NFKBIA/HLA-DPA1/HLA-DPB1/VIM/HLA-DQA1/HLA-C/CXCL10/JUN	8.14177814570799
Human Diseases	Cardiovascular disease	hsa05415	Diabetic cardiomyopathy	12/76	205/9376	7.22156611039795	MT-ND3/MT-CO3/MT-ATP6/MT-CO2/MT-CYB/CTSD/MT-ND1/MT-ND2/MT-CO1/MT-ND4/CYBB/CYBA	8.14177814570799
Human Diseases	Immune disease	hsa05310	Asthma	6/76	32/9376	23.1315789473684	HLA-DRA/HLA-DRB1/HLA-DPA1/HLA-DPB1/FCER1G/HLA-DQA1	11.3363157427839
Human Diseases	Infectious disease: viral	hsa05166	Human T-cell leukemia virus 1 infection	12/76	224/9376	6.60902255639098	HLA-DRA/HLA-DRB1/HLA-B/HLA-A/NFKBIA/HLA-DPA1/HLA-DPB1/ITGB2/HLA-DQA1/HLA-C/ZFP36/JUN	7.68075920500047
Environmental Information Processing	Signaling molecules and interaction	hsa04514	Cell adhesion molecule (CAM) interaction	10/76	160/9376	7.71052631578947	HLA-DRA/HLA-DRB1/HLA-B/HLA-A/HLA-DPA1/HLA-DPB1/ITGB2/HLA-DQA1/PTPRC/HLA-C	7.73920413649774
Human Diseases	Immune disease	hsa05321	Inflammatory bowel disease	7/76	66/9376	13.0845295055821	HLA-DRA/HLA-DRB1/HLA-DPA1/HLA-DPB1/HLA-DQA1/IL1B/JUN	8.9059003982433
Metabolism	Energy metabolism	hsa00190	Oxidative phosphorylation	9/76	138/9376	8.04576659038902	MT-ND3/MT-CO3/MT-ATP6/MT-CO2/MT-CYB/MT-ND1/MT-ND2/MT-CO1/MT-ND4	7.53754254064493
Human Diseases	Immune disease	hsa05322	Systemic lupus erythematosus	9/76	143/9376	7.76444608023556	HLA-DRA/HLA-DRB1/HLA-DPA1/C1QA/HLA-DPB1/C1QB/FCGR3A/HLA-DQA1/C1QC	7.36851208879594
Organismal Systems	Immune system	hsa04621	NOD-like receptor signaling pathway	10/76	187/9376	6.5972417675204	NFKBIA/TXNIP/CYBB/CTSB/IL1B/CYBA/BIRC3/GBP5/CXCL2/JUN	6.9889463041535
Organismal Systems	Immune system	hsa04659	Th17 cell differentiation	8/76	109/9376	9.05456301303718	HLA-DRA/HLA-DRB1/NFKBIA/HLA-DPA1/HLA-DPB1/HLA-DQA1/IL1B/JUN	7.6460407976148
Human Diseases	Neurodegenerative disease	hsa05016	Huntington disease	12/76	308/9376	4.80656185919344	MT-ND3/MT-CO3/MT-ATP6/MT-CO2/MT-CYB/MT-ND1/MT-ND2/MT-CO1/SOD2/MT-ND4/GPX1/TUBA1B	6.14049602197733
Human Diseases	Neurodegenerative disease	hsa05014	Amyotrophic lateral sclerosis	13/76	368/9376	4.35812356979405	MT-ND3/MT-CO3/MT-ATP6/MT-CO2/MT-CYB/PFN1/ACTB/MT-ND1/MT-ND2/MT-CO1/MT-ND4/GPX1/TUBA1B	5.94096992150359
Organismal Systems	Immune system	hsa04658	Th1 and Th2 cell differentiation	7/76	93/9376	9.28579513299377	HLA-DRA/HLA-DRB1/NFKBIA/HLA-DPA1/HLA-DPB1/HLA-DQA1/JUN	7.25909450146776
Human Diseases	Infectious disease: viral	hsa05164	Influenza A	9/76	173/9376	6.41801034377852	HLA-DRA/HLA-DRB1/NFKBIA/HLA-DPA1/ACTB/HLA-DPB1/HLA-DQA1/IL1B/CXCL10	6.50203241743597
Human Diseases	Neurodegenerative disease	hsa05010	Alzheimer disease	13/76	388/9376	4.13347802495931	MT-ND3/MT-CO3/MT-ATP6/MT-CO2/MT-CYB/APOE/MT-ND1/MT-ND2/MT-CO1/MT-ND4/CYBB/IL1B/TUBA1B	5.69851826119928
Cellular Processes	Cell growth and death	hsa04210	Apoptosis	8/76	137/9376	7.20399538993469	CTSD/NFKBIA/ACTB/CTSS/CTSB/BIRC3/TUBA1B/JUN	6.61256914807132
Organismal Systems	Environmental adaptation	hsa04714	Thermogenesis	10/76	235/9376	5.24972004479283	MT-ND3/MT-CO3/MT-ATP6/MT-CO2/MT-CYB/ACTB/MT-ND1/MT-ND2/MT-CO1/MT-ND4	5.96414726065791
Human Diseases	Infectious disease: parasitic	hsa05142	Chagas disease	7/76	103/9376	8.38426162493613	NFKBIA/C1QA/C1QB/CCL3/IL1B/C1QC/JUN	6.8118726154853
Organismal Systems	Immune system	hsa04620	Toll-like receptor signaling pathway	7/76	109/9376	7.92274263640753	NFKBIA/CXCL9/SPP1/CCL3/IL1B/CXCL10/JUN	6.57162561689368
Human Diseases	Infectious disease: parasitic	hsa05145	Toxoplasmosis	7/76	112/9376	7.71052631578947	HLA-DRA/HLA-DRB1/NFKBIA/HLA-DPA1/HLA-DPB1/HLA-DQA1/BIRC3	6.45828612692348
Human Diseases	Infectious disease: bacterial	hsa05133	Pertussis	6/76	78/9376	9.48987854251012	C1QA/C1QB/ITGB2/IL1B/C1QC/JUN	6.80620409054298
Environmental Information Processing	Signal transduction	hsa04668	TNF signaling pathway	7/76	119/9376	7.25696594427245	JUNB/NFKBIA/IL1B/CXCL10/BIRC3/CXCL2/JUN	6.20944950945039
Organismal Systems	Immune system	hsa04672	Intestinal immune network for IgA production	5/76	50/9376	12.3368421052632	HLA-DRA/HLA-DRB1/HLA-DPA1/HLA-DPB1/HLA-DQA1	7.26574839569946
Human Diseases	Infectious disease: parasitic	hsa05144	Malaria	5/76	50/9376	12.3368421052632	HBA2/HBA1/HBB/ITGB2/IL1B	7.26574839569946
Human Diseases	Neurodegenerative disease	hsa05012	Parkinson disease	10/76	268/9376	4.60329929300864	MT-ND3/MT-CO3/MT-ATP6/MT-CO2/MT-CYB/MT-ND1/MT-ND2/MT-CO1/MT-ND4/TUBA1B	5.41012354328761
Human Diseases	Cardiovascular disease	hsa05417	Lipid and atherosclerosis	9/76	216/9376	5.14035087719298	NFKBIA/SOD2/OLR1/CCL3/CYBB/IL1B/CYBA/CXCL2/JUN	5.56502662003718
Organismal Systems	Immune system	hsa04650	Natural killer cell mediated cytotoxicity	7/76	133/9376	6.49307479224377	HLA-B/HLA-A/TYROBP/FCGR3A/ITGB2/FCER1G/HLA-C	5.76747627019739
Human Diseases	Neurodegenerative disease	hsa05022	Pathways of neurodegeneration - multiple diseases	13/76	480/9376	3.34122807017544	MT-ND3/MT-CO3/MT-ATP6/MT-CO2/MT-CYB/MT-ND1/MT-ND2/MT-CO1/MT-ND4/GPX1/CYBB/IL1B/TUBA1B	4.76012014139448
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	9/76	238/9376	4.66519239274657	NFKBIA/C1QA/RPL13/C1QB/CYBB/IL1B/CXCL10/C1QC/JUN	5.17738711127647
Organismal Systems	Development and regeneration	hsa04380	Osteoclast differentiation	7/76	142/9376	6.0815418828762	JUNB/NFKBIA/TYROBP/FCGR3A/IL1B/CYBA/JUN	5.51563738520641
Organismal Systems	Immune system	hsa04640	Hematopoietic cell lineage	6/76	100/9376	7.40210526315789	HLA-DRA/HLA-DRB1/HLA-DPA1/HLA-DPB1/HLA-DQA1/IL1B	5.81826369732991
Human Diseases	Infectious disease: parasitic	hsa05143	African trypanosomiasis	4/76	37/9376	13.3371266002845	HBA2/HBA1/HBB/IL1B	6.79697473742186
Organismal Systems	Immune system	hsa04610	Complement and coagulation cascades	5/76	88/9376	7.00956937799043	C1QA/C1QB/ITGB2/C1QC/SERPINA1	5.12005405496159
Human Diseases	Infectious disease: bacterial	hsa05132	Salmonella infection	8/76	248/9376	3.97962648556876	PFN1/NFKBIA/ACTB/PTPRC/IL1B/BIRC3/TUBA1B/JUN	4.29883534301687
Organismal Systems	Immune system	hsa04657	IL-17 signaling pathway	5/76	94/9376	6.56215005599104	NFKBIA/IL1B/CXCL10/CXCL2/JUN	4.8993312757045
Human Diseases	Infectious disease: viral	hsa05167	Kaposi sarcoma-associated herpesvirus infection	7/76	196/9376	4.40601503759398	HLA-B/HLA-A/NFKBIA/HLA-C/ZFP36/CXCL2/JUN	4.35616394545909
Human Diseases	Infectious disease: bacterial	hsa05134	Legionellosis	4/76	56/9376	8.81203007518797	NFKBIA/ITGB2/IL1B/CXCL2	5.30030576496612
Human Diseases	Endocrine and metabolic disease	hsa04936	Alcoholic liver disease	6/76	144/9376	5.14035087719298	NFKBIA/C1QA/C1QB/IL1B/C1QC/CXCL2	4.52607197024331
Environmental Information Processing	Signaling molecules and interaction	hsa04061	Viral protein interaction with cytokine and cytokine receptor	5/76	100/9376	6.16842105263158	CXCL9/CCL3/CXCL10/CXCL13/CXCL2	4.69708562214565
Human Diseases	Endocrine and metabolic disease	hsa04932	Non-alcoholic fatty liver disease	6/76	157/9376	4.71471672812605	MT-CO3/MT-CO2/MT-CYB/MT-CO1/IL1B/JUN	4.24311282909905
Organismal Systems	Immune system	hsa04062	Chemokine signaling pathway	6/76	193/9376	3.83528770111808	NFKBIA/CXCL9/CCL3/CXCL10/CXCL13/CXCL2	3.59777878382759
Cellular Processes	Cell growth and death	hsa04216	Ferroptosis	3/76	42/9376	8.81203007518797	FTH1/FTL/CYBB	4.58675574481341
Organismal Systems	Circulatory system	hsa04260	Cardiac muscle contraction	4/76	87/9376	5.67211131276467	MT-CO3/MT-CO2/MT-CYB/MT-CO1	3.95766733297166
Human Diseases	Infectious disease: parasitic	hsa05146	Amoebiasis	4/76	103/9376	4.79100664282064	HSPB1/ITGB2/IL1B/CXCL2	3.49714780529275
Human Diseases	Infectious disease: viral	hsa05163	Human cytomegalovirus infection	6/76	227/9376	3.26083932297705	HLA-B/HLA-A/NFKBIA/CCL3/HLA-C/IL1B	3.11707156338492
Environmental Information Processing	Signaling molecules and interaction	hsa04060	Cytokine-cytokine receptor interaction	7/76	298/9376	2.89791593076651	CXCL9/CCL3/IL1B/CXCL10/CXCL13/CXCL2/IL1RN	3.00982312132044
Environmental Information Processing	Signal transduction	hsa04064	NF-kappa B signaling pathway	4/76	105/9376	4.69974937343358	NFKBIA/IL1B/BIRC3/CXCL2	3.4463122548536
Organismal Systems	Immune system	hsa04625	C-type lectin receptor signaling pathway	4/76	105/9376	4.69974937343358	NFKBIA/FCER1G/IL1B/JUN	3.4463122548536
Cellular Processes	Cell growth and death	hsa04217	Necroptosis	5/76	168/9376	3.67167919799499	FTH1/FTL/CYBB/IL1B/BIRC3	3.15869181196469
Organismal Systems	Digestive system	hsa04978	Mineral absorption	3/76	61/9376	6.06729939603106	FTH1/FTL/MT2A	3.58922771699196
Organismal Systems	Immune system	hsa04670	Leukocyte transendothelial migration	4/76	116/9376	4.2540834845735	ACTB/ITGB2/CYBB/CYBA	3.18788871284465
Human Diseases	Infectious disease: bacterial	hsa05120	Epithelial cell signaling in Helicobacter pylori infection	3/76	71/9376	5.21275018532246	NFKBIA/CXCL2/JUN	3.22097721058629
Organismal Systems	Immune system	hsa04613	Neutrophil extracellular trap formation	5/76	195/9376	3.16329284750337	ACTB/FCGR3A/ITGB2/CYBB/CYBA	2.75955202704895
Human Diseases	Infectious disease: bacterial	hsa05130	Pathogenic Escherichia coli infection	5/76	200/9376	3.08421052631579	NFKBIA/ACTB/IL1B/TUBA1B/JUN	2.69327587192288
Human Diseases	Cancer: overview	hsa05203	Viral carcinogenesis	5/76	205/9376	3.00898587933248	HLA-B/HLA-A/NFKBIA/HLA-C/JUN	2.62903536459229
Human Diseases	Infectious disease: bacterial	hsa05135	Yersinia infection	4/76	138/9376	3.57589626239512	NFKBIA/ACTB/IL1B/JUN	2.75568703689054
Human Diseases	Cardiovascular disease	hsa05418	Fluid shear stress and atherosclerosis	4/76	142/9376	3.47516679021497	ACTB/IL1B/CYBA/JUN	2.6866102449605
Human Diseases	Infectious disease: viral	hsa05170	Human immunodeficiency virus 1 infection	5/76	214/9376	2.88243974422036	HLA-B/HLA-A/NFKBIA/HLA-C/JUN	2.51816269941678
Organismal Systems	Immune system	hsa04623	Cytosolic DNA-sensing pathway	3/76	83/9376	4.45909955611921	NFKBIA/IL1B/CXCL10	2.86137711422936
Organismal Systems	Nervous system	hsa04723	Retrograde endocannabinoid signaling	4/76	149/9376	3.31190392087602	MT-ND3/MT-ND1/MT-ND2/MT-ND4	2.57148275088462
Cellular Processes	Transport and catabolism	hsa04148	Efferocytosis	4/76	157/9376	3.14314448541736	C1QA/C1QB/DUSP2/C1QC	2.44799389192584
Human Diseases	Endocrine and metabolic disease	hsa04933	AGE-RAGE signaling pathway in diabetic complications	3/76	101/9376	3.66440854611777	CYBB/IL1B/JUN	2.43363535370916
Metabolism	Metabolism of cofactors and vitamins	hsa00860	Porphyrin metabolism	2/76	46/9376	5.36384439359268	FTH1/FTL	2.68199713820291
Human Diseases	Infectious disease: bacterial	hsa05131	Shigellosis	5/76	253/9376	2.43811108799667	PFN1/NFKBIA/ACTB/IL1B/JUN	2.0962101424467
Organismal Systems	Digestive system	hsa04979	Cholesterol metabolism	2/76	52/9376	4.74493927125506	APOC1/APOE	2.44791469220924
Organismal Systems	Immune system	hsa04660	T cell receptor signaling pathway	3/76	122/9376	3.03364969801553	NFKBIA/PTPRC/JUN	2.04381825739878
Cellular Processes	Cellular community - eukaryotes	hsa04510	Focal adhesion	4/76	203/9376	2.43090484832772	ACTB/SPP1/BIRC3/JUN	1.86317666990307
Human Diseases	Infectious disease: viral	hsa05162	Measles	3/76	136/9376	2.72136222910217	NFKBIA/IL1B/JUN	1.82791795121674
Organismal Systems	Immune system	hsa04622	RIG-I-like receptor signaling pathway	2/76	72/9376	3.42690058479532	NFKBIA/CXCL10	1.86867744526823
Cellular Processes	Cell motility	hsa04810	Regulation of actin cytoskeleton	4/76	232/9376	2.12704174228675	TMSB4X/PFN1/ACTB/ITGB2	1.57132798455891
NA	NA	hsa04518	Integrin signaling	3/76	154/9376	2.40328092959672	ACTB/ITGB2/SPP1	1.58724286968534
Organismal Systems	Endocrine system	hsa04921	Oxytocin signaling pathway	3/76	154/9376	2.40328092959672	ACTB/RGS2/JUN	1.58724286968534
Cellular Processes	Cell growth and death	hsa04218	Cellular senescence	3/76	157/9376	2.35735836406302	HLA-B/HLA-A/HLA-C	1.55043442333923
Environmental Information Processing	Signal transduction	hsa04390	Hippo signaling pathway	3/76	157/9376	2.35735836406302	ACTB/ITGB2/BIRC3	1.55043442333923
Cellular Processes	Transport and catabolism	hsa04142	Lysosome biogenesis	4/76	250/9376	1.97389473684211	CTSD/LAPTM5/CTSS/CTSB	1.41088868646854
Cellular Processes	Cellular community - eukaryotes	hsa04530	Tight junction	3/76	170/9376	2.17708978328173	ACTB/TUBA1B/JUN	1.40006927726831
Human Diseases	Cancer: overview	hsa05235	PD-L1 expression and PD-1 checkpoint pathway in cancer	2/76	90/9376	2.74152046783626	NFKBIA/JUN	1.50067434529423
Organismal Systems	Immune system	hsa04662	B cell receptor signaling pathway	2/76	91/9376	2.71139386928861	NFKBIA/JUN	1.48296422441784
Organismal Systems	Digestive system	hsa04970	Salivary secretion	2/76	93/9376	2.65308432371251	LYZ/CST3	1.4482490976564
Human Diseases	Cancer: specific types	hsa05222	Small cell lung cancer	2/76	93/9376	2.65308432371251	NFKBIA/BIRC3	1.4482490976564
Organismal Systems	Immune system	hsa04666	Fc gamma R-mediated phagocytosis	2/76	98/9376	2.51772287862513	FCGR3A/PTPRC	1.36530378648749
Human Diseases	Drug resistance: antineoplastic	hsa01523	Antifolate resistance	1/76	30/9376	4.11228070175439	IL1B	1.54339631466192
Environmental Information Processing	Signal transduction	hsa04010	MAPK signaling pathway	4/76	300/9376	1.64491228070175	HSPB1/IL1B/DUSP2/JUN	1.02627793309737
Human Diseases	Cancer: overview	hsa05205	Proteoglycans in cancer	3/76	204/9376	1.81424148606811	ACTB/LUM/DCN	1.06288737104024
Cellular Processes	Cell growth and death	hsa04215	Apoptosis - multiple species	1/76	32/9376	3.85526315789474	BIRC3	1.46253300605476
Environmental Information Processing	Signal transduction	hsa04015	Rap1 signaling pathway	3/76	212/9376	1.74577954319762	PFN1/ACTB/ITGB2	0.992857262064837
Organismal Systems	Nervous system	hsa04722	Neurotrophin signaling pathway	2/76	120/9376	2.05614035087719	NFKBIA/JUN	1.0525713522901
Human Diseases	Immune disease	hsa05340	Primary immunodeficiency	1/76	38/9376	3.24653739612188	PTPRC	1.25438102515844
Genetic Information Processing	Translation	hsa03010	Ribosome	3/76	222/9376	1.66714082503556	MT-RNR2/MT-RNR1/RPL13	0.909367671902964
Environmental Information Processing	Signal transduction	hsa04071	Sphingolipid signaling pathway	2/76	125/9376	1.97389473684211	CTSD/FCER1G	0.990885891604079
Organismal Systems	Immune system	hsa04611	Platelet activation	2/76	126/9376	1.95822890559733	ACTB/FCER1G	0.978891672044117
Human Diseases	Infectious disease: viral	hsa05165	Human papillomavirus infection	4/76	333/9376	1.48190295558717	HLA-B/HLA-A/SPP1/HLA-C	0.809424603700494
Organismal Systems	Endocrine system	hsa04926	Relaxin signaling pathway	2/76	130/9376	1.89797570850202	NFKBIA/JUN	0.931987913464648
Human Diseases	Cancer: specific types	hsa05219	Bladder cancer	1/76	41/9376	3.00898587933248	TYMP	1.1653667198359
Cellular Processes	Cell motility	hsa04820	Cytoskeleton in muscle cells	3/76	233/9376	1.58843460582787	ACTB/VIM/DCN	0.822210022404569
Organismal Systems	Endocrine system	hsa04915	Estrogen signaling pathway	2/76	139/9376	1.77508519500189	CTSD/JUN	0.832228012371957
Human Diseases	Substance dependence	hsa05030	Cocaine addiction	1/76	49/9376	2.51772287862513	JUN	0.96287628967578
Cellular Processes	Transport and catabolism	hsa04144	Endocytosis	3/76	250/9376	1.48042105263158	HLA-B/HLA-A/HLA-C	0.69598962008673
Human Diseases	Infectious disease: bacterial	hsa05110	Vibrio cholerae infection	1/76	51/9376	2.41898864809082	ACTB	0.918524085805873
Human Diseases	Infectious disease: viral	hsa05160	Hepatitis C	2/76	156/9376	1.58164642375169	NFKBIA/CXCL10	0.662226965344863
Human Diseases	Infectious disease: viral	hsa05161	Hepatitis B	2/76	163/9376	1.513722957701	NFKBIA/JUN	0.598099171713967
Metabolism	Nucleotide metabolism	hsa00240	Pyrimidine metabolism	1/76	59/9376	2.09099018733274	TYMP	0.759905805765214
Metabolism	Metabolism of other amino acids	hsa00480	Glutathione metabolism	1/76	59/9376	2.09099018733274	GPX1	0.759905805765214
Environmental Information Processing	Signal transduction	hsa04370	VEGF signaling pathway	1/76	60/9376	2.05614035087719	HSPB1	0.741879688441631
Organismal Systems	Aging	hsa04213	Longevity regulating pathway - multiple species	1/76	62/9376	1.98981324278438	SOD2	0.706857626324381
Cellular Processes	Transport and catabolism	hsa04140	Autophagy - animal	2/76	169/9376	1.45998131423233	CTSD/CTSB	0.545475727950347
Organismal Systems	Endocrine system	hsa04929	GnRH secretion	1/76	65/9376	1.89797570850202	SPP1	0.656710656402575
Organismal Systems	Immune system	hsa04664	Fc epsilon RI signaling pathway	1/76	69/9376	1.78794813119756	FCER1G	0.593838401222372
Organismal Systems	Endocrine system	hsa04924	Renin secretion	1/76	69/9376	1.78794813119756	CTSB	0.593838401222372
Human Diseases	Substance dependence	hsa05031	Amphetamine addiction	1/76	69/9376	1.78794813119756	JUN	0.593838401222372
Organismal Systems	Endocrine system	hsa04920	Adipocytokine signaling pathway	1/76	70/9376	1.76240601503759	NFKBIA	0.578768345121178
Human Diseases	Cancer: specific types	hsa05211	Renal cell carcinoma	1/76	70/9376	1.76240601503759	JUN	0.578768345121178
NA	NA	hsa04517	IgSF CAM signaling	3/76	299/9376	1.23781024467523	ACTB/ITGB2/TUBA1B	0.37778607520661
Human Diseases	Drug resistance: antineoplastic	hsa01524	Platinum drug resistance	1/76	75/9376	1.64491228070175	BIRC3	0.506894310482664
Organismal Systems	Endocrine system	hsa04918	Thyroid hormone synthesis	1/76	75/9376	1.64491228070175	GPX1	0.506894310482664
Organismal Systems	Endocrine system	hsa03320	PPAR signaling pathway	1/76	76/9376	1.62326869806094	OLR1	0.493164263099417
Organismal Systems	Digestive system	hsa04971	Gastric acid secretion	1/76	76/9376	1.62326869806094	ACTB	0.493164263099417
Human Diseases	Cancer: specific types	hsa05220	Chronic myeloid leukemia	1/76	77/9376	1.60218728639781	NFKBIA	0.479633800724959
Cellular Processes	Cell motility	hsa04814	Motor proteins	2/76	194/9376	1.27183939229517	ACTB/TUBA1B	0.345856204767022
Human Diseases	Infectious disease: bacterial	hsa05100	Bacterial invasion of epithelial cells	1/76	78/9376	1.58164642375169	ACTB	0.46629692624766
Metabolism	Xenobiotics biodegradation and metabolism	hsa00983	Drug metabolism - other enzymes	1/76	82/9376	1.50449293966624	TYMP	0.414774114561131
Cellular Processes	Transport and catabolism	hsa04146	Peroxisome	1/76	83/9376	1.4863665187064	SOD2	0.402323784897143
Metabolism	Global and overview maps	hsa01232	Nucleotide metabolism	1/76	85/9376	1.45139318885449	TYMP	0.377906354402205
Environmental Information Processing	Signal transduction	hsa04012	ErbB signaling pathway	1/76	86/9376	1.43451652386781	JUN	0.365930513595306
Human Diseases	Cardiovascular disease	hsa05412	Arrhythmogenic right ventricular cardiomyopathy	1/76	86/9376	1.43451652386781	ACTB	0.365930513595306
Human Diseases	Cancer: specific types	hsa05210	Colorectal cancer	1/76	87/9376	1.41802782819117	JUN	0.354104380044467
Environmental Information Processing	Signaling molecules and interaction	hsa04512	ECM-receptor interaction	1/76	89/9376	1.38616203429923	SPP1	0.330885559641311
Cellular Processes	Cellular community - eukaryotes	hsa04540	Gap junction	1/76	89/9376	1.38616203429923	TUBA1B	0.330885559641311
Organismal Systems	Aging	hsa04211	Longevity regulating pathway	1/76	90/9376	1.37076023391813	SOD2	0.319485404605958
Cellular Processes	Cellular community - eukaryotes	hsa04520	Adherens junction	1/76	93/9376	1.32654216185625	ACTB	0.286080016894126
Organismal Systems	Endocrine system	hsa04912	GnRH signaling pathway	1/76	93/9376	1.32654216185625	JUN	0.286080016894126
Environmental Information Processing	Signal transduction	hsa04024	cAMP signaling pathway	2/76	226/9376	1.09175593851886	NFKBIA/JUN	0.126220185566055
Human Diseases	Drug resistance: antineoplastic	hsa01522	Endocrine resistance	1/76	99/9376	1.2461456671983	JUN	0.222565053910839
Organismal Systems	Sensory system	hsa04750	Inflammatory mediator regulation of TRP channels	1/76	99/9376	1.2461456671983	IL1B	0.222565053910839
Human Diseases	Cancer: overview	hsa05231	Choline metabolism in cancer	1/76	99/9376	1.2461456671983	JUN	0.222565053910839
Human Diseases	Cardiovascular disease	hsa05410	Hypertrophic cardiomyopathy	1/76	99/9376	1.2461456671983	ACTB	0.222565053910839
Cellular Processes	Transport and catabolism	hsa04137	Mitophagy - animal	1/76	105/9376	1.1749373433584	JUN	0.162953932657351
Human Diseases	Cardiovascular disease	hsa05414	Dilated cardiomyopathy	1/76	105/9376	1.1749373433584	ACTB	0.162953932657351
Human Diseases	Cancer: specific types	hsa05215	Prostate cancer	1/76	106/9376	1.16385302879841	NFKBIA	0.1533622598061
Human Diseases	Endocrine and metabolic disease	hsa04931	Insulin resistance	1/76	109/9376	1.13182037662965	NFKBIA	0.125134532566923
Environmental Information Processing	Signal transduction	hsa04066	HIF-1 signaling pathway	1/76	110/9376	1.12153110047847	CYBB	0.115901374187602
Environmental Information Processing	Signal transduction	hsa04350	TGF-beta signaling pathway	1/76	110/9376	1.12153110047847	DCN	0.115901374187602
Genetic Information Processing	Chromosome	hsa03082	ATP-dependent chromatin remodeling	1/76	117/9376	1.05443094916779	ACTB	0.0535559535855093
Organismal Systems	Endocrine system	hsa04919	Thyroid hormone signaling pathway	1/76	122/9376	1.01121656600518	ACTB	0.0112726505499296
Organismal Systems	Endocrine system	hsa04935	Growth hormone synthesis, secretion and action	1/76	122/9376	1.01121656600518	JUNB	0.0112726505499296
NA	NA	hsa04519	Cadherin signaling	3/76	404/9376	0.916102136529442	NFKBIA/ACTB/VIM	-0.155828866442739
Environmental Information Processing	Signal transduction	hsa04068	FoxO signaling pathway	1/76	133/9376	0.927582113177681	SOD2	-0.0760354554748305
Environmental Information Processing	Signal transduction	hsa04371	Apelin signaling pathway	1/76	140/9376	0.881203007518797	SPP1	-0.128020188335315
Genetic Information Processing	Folding, sorting and degradation	hsa04120	Ubiquitin mediated proteolysis	1/76	142/9376	0.868791697553744	BIRC3	-0.142416895285417
Human Diseases	Cancer: specific types	hsa05224	Breast cancer	1/76	148/9376	0.833570412517781	JUN	-0.184483938445699
Environmental Information Processing	Signal transduction	hsa04072	Phospholipase D signaling pathway	1/76	149/9376	0.827975980219004	FCER1G	-0.191338747086449
Environmental Information Processing	Signal transduction	hsa04022	cGMP-PKG signaling pathway	1/76	166/9376	0.743183259353202	RGS2	-0.301785603981552
Human Diseases	Cancer: specific types	hsa05225	Hepatocellular carcinoma	1/76	170/9376	0.725696594427245	ACTB	-0.326265486496507
Environmental Information Processing	Signal transduction	hsa04310	Wnt signaling pathway	1/76	178/9376	0.693081017149616	JUN	-0.373712830778481
Human Diseases	Cancer: overview	hsa05202	Transcriptional misregulation in cancer	1/76	201/9376	0.613773239067819	BIRC3	-0.50036660216564
Human Diseases	Cancer: overview	hsa05207	Chemical carcinogenesis - receptor activation	1/76	217/9376	0.568518069366966	JUN	-0.581325549448839
Human Diseases	Cancer: overview	hsa05206	MicroRNAs in cancer	1/76	323/9376	0.381945576014339	VIM	-1.02183948541461
Environmental Information Processing	Signal transduction	hsa04151	PI3K-Akt signaling pathway	1/76	362/9376	0.340796743239314	SPP1	-1.15628745213391
Organismal Systems	Sensory system	hsa04740	Olfactory transduction	1/76	449/9376	0.274762630406752	RGS2	-1.42364444298251