category subcategory ID Description GeneRatio BgRatio FoldEnrichment geneName zScore Organismal Systems Immune system hsa04612 Antigen processing and presentation 7/69 82/9376 11.5998586072817 HLA-DRB1/HLA-C/B2M/PSME2/CD74/HLA-G/TAP1 8.30062876313682 Organismal Systems Immune system hsa04610 Complement and coagulation cascades 6/69 88/9376 9.26482213438735 SERPINE1/SERPING1/ITGB2/SERPINA1/SERPINE2/C2 6.70685737554397 Organismal Systems Immune system hsa04621 NOD-like receptor signaling pathway 8/69 187/9376 5.8132217313803 GBP1/CYBA/GBP5/STAT1/CYBB/GBP4/TXN/GBP2 5.72437231900828 Environmental Information Processing Signaling molecules and interaction hsa04061 Viral protein interaction with cytokine and cytokine receptor 6/69 100/9376 8.15304347826087 CXCL9/TNFSF10/CXCL10/IL6ST/CXCL11/IL2RG 6.19178433996885 Human Diseases Infectious disease: viral hsa05169 Epstein-Barr virus infection 8/69 205/9376 5.30279250618593 HLA-DRB1/HLA-C/B2M/STAT1/CXCL10/CD40/HLA-G/TAP1 5.36320396882338 Cellular Processes Transport and catabolism hsa04145 Phagosome 7/69 155/9376 6.13669939223936 HLA-DRB1/HLA-C/CYBA/ITGB2/CYBB/HLA-G/TAP1 5.55221551743726 Human Diseases Cardiovascular disease hsa05416 Viral myocarditis 5/69 70/9376 9.70600414078675 HLA-DRB1/HLA-C/ITGB2/CD40/HLA-G 6.29494140455964 Human Diseases Immune disease hsa05330 Allograft rejection 4/69 39/9376 13.9368264585656 HLA-DRB1/HLA-C/CD40/HLA-G 6.97046423259945 Human Diseases Infectious disease: parasitic hsa05140 Leishmaniasis 5/69 78/9376 8.71051653660349 HLA-DRB1/CYBA/STAT1/ITGB2/CYBB 5.8876411221321 Environmental Information Processing Signaling molecules and interaction hsa04060 Cytokine-cytokine receptor interaction 9/69 298/9376 4.10388094543332 CXCL9/TNFSF10/CXCL10/EBI3/IL6ST/IL32/CXCL11/CD40/IL2RG 4.68838668908749 Human Diseases Infectious disease: viral hsa05168 Herpes simplex virus 1 infection 7/69 180/9376 5.28438003220612 HLA-DRB1/HLA-C/B2M/STAT1/CD74/HLA-G/TAP1 4.99723858287771 Human Diseases Immune disease hsa05320 Autoimmune thyroid disease 4/69 54/9376 10.0654857756307 HLA-DRB1/HLA-C/CD40/HLA-G 5.75226304979753 Environmental Information Processing Signaling molecules and interaction hsa04514 Cell adhesion molecule (CAM) interaction 6/69 160/9376 5.09565217391304 HLA-DRB1/HLA-C/ITGB2/PTPRF/CD40/HLA-G 4.49901200140574 Organismal Systems Immune system hsa04620 Toll-like receptor signaling pathway 5/69 109/9376 6.23321366839516 CXCL9/STAT1/CXCL10/CXCL11/CD40 4.73170282715944 Organismal Systems Immune system hsa04659 Th17 cell differentiation 5/69 109/9376 6.23321366839516 HLA-DRB1/STAT1/EBI3/IL6ST/IL2RG 4.73170282715944 Human Diseases Infectious disease: viral hsa05166 Human T-cell leukemia virus 1 infection 7/69 224/9376 4.2463768115942 HLA-DRB1/HLA-C/B2M/ITGB2/CD40/IL2RG/HLA-G 4.23418917633114 Human Diseases Immune disease hsa05310 Asthma 3/69 32/9376 12.7391304347826 HLA-DRB1/PRG2/CD40 5.72729863732417 Human Diseases Infectious disease: bacterial hsa05133 Pertussis 4/69 78/9376 6.96841322928279 SERPING1/ITGB2/IRF1/C2 4.55739573292995 Human Diseases Immune disease hsa05340 Primary immunodeficiency 3/69 38/9376 10.7276887871854 CD40/IL2RG/TAP1 5.1734452590886 Metabolism Amino acid metabolism hsa00380 Tryptophan metabolism 3/69 42/9376 9.70600414078675 AOC1/IDO1/IL4I1 4.86872161346608 Human Diseases Endocrine and metabolic disease hsa04940 Type I diabetes mellitus 3/69 44/9376 9.26482213438735 HLA-DRB1/HLA-C/HLA-G 4.73127085781384 Human Diseases Immune disease hsa05332 Graft-versus-host disease 3/69 45/9376 9.05893719806763 HLA-DRB1/HLA-C/HLA-G 4.66579077582036 Human Diseases Infectious disease: bacterial hsa05150 Staphylococcus aureus infection 4/69 99/9376 5.49026496852584 HLA-DRB1/ITGB2/KRT19/C2 3.86715086346141 Human Diseases Endocrine and metabolic disease hsa04933 AGE-RAGE signaling pathway in diabetic complications 4/69 101/9376 5.38154685033721 FN1/STAT1/SERPINE1/CYBB 3.81185624736706 Organismal Systems Digestive system hsa04978 Mineral absorption 3/69 61/9376 6.68282252316465 MT2A/FTH1/MT1E 3.83391877362323 Human Diseases Infectious disease: bacterial hsa05152 Tuberculosis 5/69 181/9376 3.7537032588678 HLA-DRB1/STAT1/ITGB2/CD74/CLEC4E 3.22096411101462 Human Diseases Immune disease hsa05321 Inflammatory bowel disease 3/69 66/9376 6.17654808959157 HLA-DRB1/STAT1/IL2RG 3.63364676944362 Human Diseases Infectious disease: viral hsa05167 Kaposi sarcoma-associated herpesvirus infection 5/69 196/9376 3.46643005028098 HLA-C/STAT1/IL6ST/UBC/HLA-G 3.00455960993239 Organismal Systems Immune system hsa04650 Natural killer cell mediated cytotoxicity 4/69 133/9376 4.08673858559442 HLA-C/TNFSF10/ITGB2/HLA-G 3.08691393616665 Human Diseases Infectious disease: viral hsa05170 Human immunodeficiency virus 1 infection 5/69 214/9376 3.17486116754707 HLA-C/B2M/APOBEC3A/HLA-G/TAP1 2.77107709451084 Cellular Processes Cell growth and death hsa04218 Cellular senescence 4/69 157/9376 3.46201421582203 HLA-C/SERPINE1/IGFBP3/HLA-G 2.67857494119733 Human Diseases Infectious disease: viral hsa05171 Coronavirus disease - COVID-19 5/69 238/9376 2.8547071002314 STAT1/CXCL10/IL6ST/CYBB/C2 2.49541949051592 Organismal Systems Immune system hsa04658 Th1 and Th2 cell differentiation 3/69 93/9376 4.3833567087424 HLA-DRB1/STAT1/IL2RG 2.82325700071956 Human Diseases Immune disease hsa05323 Rheumatoid arthritis 3/69 95/9376 4.29107551487414 HLA-DRB1/FLT1/ITGB2 2.77592411923228 Cellular Processes Cell growth and death hsa04217 Necroptosis 4/69 168/9376 3.23533471359558 TNFSF10/STAT1/FTH1/CYBB 2.51721247100959 Cellular Processes Cell growth and death hsa04216 Ferroptosis 2/69 42/9376 6.47066942719117 FTH1/CYBB 3.05940199999569 Human Diseases Infectious disease: viral hsa05164 Influenza A 4/69 173/9376 3.14182792996565 HLA-DRB1/TNFSF10/STAT1/CXCL10 2.44820761663655 Organismal Systems Immune system hsa04625 C-type lectin receptor signaling pathway 3/69 105/9376 3.8824016563147 STAT1/IRF1/CLEC4E 2.55735597368282 Environmental Information Processing Signal transduction hsa04066 HIF-1 signaling pathway 3/69 110/9376 3.70592885375494 FLT1/SERPINE1/CYBB 2.45794349554993 Human Diseases Infectious disease: parasitic hsa05145 Toxoplasmosis 3/69 112/9376 3.63975155279503 HLA-DRB1/STAT1/CD40 2.41979245793302 Metabolism Amino acid metabolism hsa00330 Arginine and proline metabolism 2/69 50/9376 5.43536231884058 LAP3/AOC1 2.70752032670945 Organismal Systems Immune system hsa04672 Intestinal immune network for IgA production 2/69 50/9376 5.43536231884058 HLA-DRB1/CD40 2.70752032670945 Human Diseases Infectious disease: parasitic hsa05144 Malaria 2/69 50/9376 5.43536231884058 ITGB2/CD40 2.70752032670945 Organismal Systems Immune system hsa04062 Chemokine signaling pathway 4/69 193/9376 2.81624990613502 CXCL9/STAT1/CXCL10/CXCL11 2.19516562770245 Organismal Systems Immune system hsa04670 Leukocyte transendothelial migration 3/69 116/9376 3.51424287856072 CYBA/ITGB2/CYBB 2.34604347890172 Human Diseases Cancer: overview hsa05202 Transcriptional misregulation in cancer 4/69 201/9376 2.70416035763213 FLT1/IGFBP3/HPGD/CD40 2.10286202047951 Human Diseases Cancer: overview hsa05205 Proteoglycans in cancer 4/69 204/9376 2.6643932935493 FN1/TIMP3/IGF2/HSPG2 2.06939952225377 Human Diseases Cardiovascular disease hsa05417 Lipid and atherosclerosis 4/69 216/9376 2.51637144390768 CYBA/TNFSF10/CYBB/CD40 1.94128841408989 Metabolism Lipid metabolism hsa00590 Arachidonic acid metabolism 2/69 63/9376 4.31377961812744 HPGD/PTGES 2.27224115885858 Human Diseases Infectious disease: viral hsa05163 Human cytomegalovirus infection 4/69 227/9376 2.39443273957735 HLA-C/B2M/HLA-G/TAP1 1.8311714658185 Organismal Systems Development and regeneration hsa04380 Osteoclast differentiation 3/69 142/9376 2.87078995713411 CYBA/STAT1/LILRB1 1.93410297759745 Human Diseases Immune disease hsa05322 Systemic lupus erythematosus 3/69 143/9376 2.85071450288842 HLA-DRB1/CD40/C2 1.9201774087729 Organismal Systems Endocrine system hsa04917 Prolactin signaling pathway 2/69 71/9376 3.82771994284548 STAT1/IRF1 2.05926722320174 Human Diseases Infectious disease: viral hsa05165 Human papillomavirus infection 5/69 333/9376 2.04030117073595 FN1/HLA-C/STAT1/IRF1/HLA-G 1.66429483420658 NA NA hsa04518 Integrin signaling 3/69 154/9376 2.64709203839639 FN1/FLT1/ITGB2 1.7744795391198 Cellular Processes Cell growth and death hsa04115 p53 signaling pathway 2/69 75/9376 3.62357487922705 SERPINE1/IGFBP3 1.9641045421941 Metabolism Amino acid metabolism hsa00360 Phenylalanine metabolism 1/69 16/9376 8.49275362318841 IL4I1 2.58266957228112 Environmental Information Processing Signal transduction hsa04630 JAK-STAT signaling pathway 3/69 168/9376 2.42650103519669 STAT1/IL6ST/IL2RG 1.60638412398173 Environmental Information Processing Signaling molecules and interaction hsa04512 ECM-receptor interaction 2/69 89/9376 3.05357433642729 FN1/HSPG2 1.67599622258472 Organismal Systems Digestive system hsa04970 Salivary secretion 2/69 93/9376 2.92223780582827 LYZ/CD38 1.60401985647256 Metabolism Amino acid metabolism hsa00340 Histidine metabolism 1/69 22/9376 6.17654808959157 AOC1 2.09294703073387 Organismal Systems Immune system hsa04640 Hematopoietic cell lineage 2/69 100/9376 2.71768115942029 HLA-DRB1/CD38 1.48685120344661 Organismal Systems Immune system hsa04613 Neutrophil extracellular trap formation 3/69 195/9376 2.09052396878484 CYBA/ITGB2/CYBB 1.3249907733196 Human Diseases Infectious disease: parasitic hsa05146 Amoebiasis 2/69 103/9376 2.63852539749543 FN1/ITGB2 1.43968336476739 Human Diseases Cancer: overview hsa05203 Viral carcinogenesis 3/69 205/9376 1.98854718981972 HLA-C/IL6ST/HLA-G 1.2321719451236 Environmental Information Processing Signal transduction hsa04015 Rap1 signaling pathway 3/69 212/9376 1.92288761279737 FLT1/ITGB2/PFN1 1.17025238161752 Metabolism Carbohydrate metabolism hsa00030 Pentose phosphate pathway 1/69 31/9376 4.3833567087424 FBP1 1.62459199410762 Genetic Information Processing Folding, sorting and degradation hsa04130 SNARE interactions in vesicular transport 1/69 33/9376 4.11769872639438 VAMP5 1.54473244243812 Environmental Information Processing Signal transduction hsa04668 TNF signaling pathway 2/69 119/9376 2.28376568018512 CXCL10/IRF1 1.21347109721227 Organismal Systems Endocrine system hsa04919 Thyroid hormone signaling pathway 2/69 122/9376 2.22760750772155 STAT1/DIO2 1.17511408062268 Organismal Systems Endocrine system hsa04935 Growth hormone synthesis, secretion and action 2/69 122/9376 2.22760750772155 STAT1/IGFBP3 1.17511408062268 Metabolism Carbohydrate metabolism hsa00051 Fructose and mannose metabolism 1/69 35/9376 3.8824016563147 FBP1 1.47094746254932 Metabolism Amino acid metabolism hsa00250 Alanine, aspartate and glutamate metabolism 1/69 37/9376 3.67254210732472 IL4I1 1.40242794638201 Metabolism Amino acid metabolism hsa00350 Tyrosine metabolism 1/69 37/9376 3.67254210732472 IL4I1 1.40242794638201 Human Diseases Infectious disease: parasitic hsa05143 African trypanosomiasis 1/69 37/9376 3.67254210732472 IDO1 1.40242794638201 Cellular Processes Cell motility hsa04810 Regulation of actin cytoskeleton 3/69 232/9376 1.75712143928036 FN1/ITGB2/PFN1 1.00541822787049 Metabolism Metabolism of cofactors and vitamins hsa00760 Nicotinate and nicotinamide metabolism 1/69 38/9376 3.57589626239512 CD38 1.36993057633045 Cellular Processes Cell motility hsa04820 Cytoskeleton in muscle cells 3/69 233/9376 1.74958014554954 FN1/TPM1/HSPG2 0.997601289704558 Human Diseases Cancer: specific types hsa05219 Bladder cancer 1/69 41/9376 3.31424531636621 TYMP 1.27864353550917 Human Diseases Infectious disease: viral hsa05162 Measles 2/69 136/9376 1.99829497016198 STAT1/IL2RG 1.00971237303184 Organismal Systems Endocrine system hsa04910 Insulin signaling pathway 2/69 138/9376 1.96933417349296 PTPRF/FBP1 0.98770991805801 Human Diseases Infectious disease: bacterial hsa05132 Salmonella infection 3/69 248/9376 1.6437587657784 TNFSF10/PFN1/TXN 0.884639866397589 Environmental Information Processing Signal transduction hsa04151 PI3K-Akt signaling pathway 4/69 362/9376 1.50148130354712 FN1/FLT1/IGF2/IL2RG 0.837829371306463 Cellular Processes Transport and catabolism hsa04144 Endocytosis 3/69 250/9376 1.63060869565217 HLA-C/IL2RG/HLA-G 0.870151861894912 Human Diseases Cardiovascular disease hsa05418 Fluid shear stress and atherosclerosis 2/69 142/9376 1.91385997142274 CYBA/TXN 0.944787673835657 Environmental Information Processing Membrane transport hsa02010 ABC transporters 1/69 45/9376 3.01964573268921 TAP1 1.16929121029331 Cellular Processes Cellular community - eukaryotes hsa04550 Signaling pathways regulating pluripotency of stem cells 2/69 144/9376 1.88727858293076 IL6ST/ID3 0.923844065612739 Metabolism Metabolism of cofactors and vitamins hsa00860 Porphyrin metabolism 1/69 46/9376 2.95400126023945 FTH1 1.14384784961357 Genetic Information Processing Folding, sorting and degradation hsa03050 Proteasome 1/69 46/9376 2.95400126023945 PSME2 1.14384784961357 Metabolism Amino acid metabolism hsa00280 Valine, leucine and isoleucine degradation 1/69 48/9376 2.83091787439613 IL4I1 1.09496576572423 NA NA hsa03272 Virion - Hepatitis viruses 1/69 48/9376 2.83091787439613 HSPG2 1.09496576572423 Human Diseases Infectious disease: viral hsa05160 Hepatitis C 2/69 156/9376 1.7421033073207 STAT1/CXCL10 0.804760278708185 Environmental Information Processing Signal transduction hsa04390 Hippo signaling pathway 2/69 157/9376 1.73100710791101 SERPINE1/ITGB2 0.795307073575857 Metabolism Amino acid metabolism hsa00270 Cysteine and methionine metabolism 1/69 54/9376 2.51637144390768 IL4I1 0.962173196499379 Human Diseases Infectious disease: viral hsa05161 Hepatitis B 2/69 163/9376 1.66728905485907 STAT1/HSPG2 0.739967413279396 Human Diseases Infectious disease: bacterial hsa05134 Legionellosis 1/69 56/9376 2.42650103519669 ITGB2 0.92185682446206 Metabolism Nucleotide metabolism hsa00240 Pyrimidine metabolism 1/69 59/9376 2.30311962662736 TYMP 0.864525027859131 Metabolism Metabolism of other amino acids hsa00480 Glutathione metabolism 1/69 59/9376 2.30311962662736 LAP3 0.864525027859131 NA NA hsa04517 IgSF CAM signaling 3/69 299/9376 1.36338519703359 SLAMF7/ITGB2/PTPRF 0.549840827917262 Metabolism Carbohydrate metabolism hsa00010 Glycolysis / Gluconeogenesis 1/69 67/9376 2.0281202682241 FBP1 0.727168627455819 Organismal Systems Immune system hsa04622 RIG-I-like receptor signaling pathway 1/69 72/9376 1.88727858293076 CXCL10 0.650723847117803 Genetic Information Processing Information processing in viruses hsa03250 Viral life cycle - HIV-1 1/69 73/9376 1.86142545165773 APOBEC3A 0.636169648916533 Organismal Systems Endocrine system hsa03320 PPAR signaling pathway 1/69 76/9376 1.78794813119756 UBC 0.593838401222372 Human Diseases Cancer: specific types hsa05212 Pancreatic cancer 1/69 77/9376 1.76472802559759 STAT1 0.580149031752614 Human Diseases Infectious disease: bacterial hsa05100 Bacterial invasion of epithelial cells 1/69 78/9376 1.7421033073207 FN1 0.566659565323524 Cellular Processes Cellular community - eukaryotes hsa04510 Focal adhesion 2/69 203/9376 1.33875919183266 FN1/FLT1 0.420134878403083 Human Diseases Cardiovascular disease hsa05415 Diabetic cardiomyopathy 2/69 205/9376 1.32569812654648 CYBA/CYBB 0.405965540383638 Metabolism Xenobiotics biodegradation and metabolism hsa00983 Drug metabolism - other enzymes 1/69 82/9376 1.6571226581831 TYMP 0.514585282644858 Organismal Systems Immune system hsa04623 Cytosolic DNA-sensing pathway 1/69 83/9376 1.63715732495198 CXCL10 0.502010827793781 Metabolism Global and overview maps hsa01232 Nucleotide metabolism 1/69 85/9376 1.59863597612958 TYMP 0.4773603820785 Organismal Systems Circulatory system hsa04260 Cardiac muscle contraction 1/69 87/9376 1.56188572380476 TPM1 0.453344623282066 NA NA hsa04382 Cornified envelope formation 2/69 217/9376 1.25238763106926 KRT19/KRT7 0.323876346352938 NA NA hsa04081 Hormone signaling 2/69 219/9376 1.24095030110516 IGF2/DIO2 0.310654930120967 Human Diseases Cancer: overview hsa05235 PD-L1 expression and PD-1 checkpoint pathway in cancer 1/69 90/9376 1.50982286634461 STAT1 0.418438418517498 Organismal Systems Immune system hsa04662 B cell receptor signaling pathway 1/69 91/9376 1.49323140627488 LILRB1 0.407085647666651 Cellular Processes Cellular community - eukaryotes hsa04520 Adherens junction 1/69 93/9376 1.46111890291413 PTPRF 0.384782712225562 Human Diseases Cancer: specific types hsa05222 Small cell lung cancer 1/69 93/9376 1.46111890291413 FN1 0.384782712225562 Organismal Systems Immune system hsa04657 IL-17 signaling pathway 1/69 94/9376 1.44557508479803 CXCL10 0.373825884699391 Human Diseases Cardiovascular disease hsa05410 Hypertrophic cardiomyopathy 1/69 99/9376 1.37256624213146 TPM1 0.320865221775153 Environmental Information Processing Signal transduction hsa04014 Ras signaling pathway 2/69 238/9376 1.14188284009256 FLT1/IGF2 0.190896559619873 Organismal Systems Digestive system hsa04972 Pancreatic secretion 1/69 102/9376 1.33219664677465 CD38 0.290447144450677 Human Diseases Infectious disease: parasitic hsa05142 Chagas disease 1/69 103/9376 1.31926269874771 SERPINE1 0.280518811048279 Environmental Information Processing Signal transduction hsa04064 NF-kappa B signaling pathway 1/69 105/9376 1.29413388543823 CD40 0.260964688019829 Cellular Processes Transport and catabolism hsa04137 Mitophagy - animal 1/69 105/9376 1.29413388543823 UBC 0.260964688019829 Human Diseases Cardiovascular disease hsa05414 Dilated cardiomyopathy 1/69 105/9376 1.29413388543823 TPM1 0.260964688019829 Organismal Systems Endocrine system hsa04922 Glucagon signaling pathway 1/69 107/9376 1.26994446701883 FBP1 0.241799392084902 Human Diseases Endocrine and metabolic disease hsa04931 Insulin resistance 1/69 109/9376 1.24664273367903 PTPRF 0.223006396107136 Environmental Information Processing Signal transduction hsa04350 TGF-beta signaling pathway 1/69 110/9376 1.23530961791831 ID3 0.213744623773112 Human Diseases Infectious disease: bacterial hsa05131 Shigellosis 2/69 253/9376 1.07418227645071 UBC/PFN1 0.102990438271725 Environmental Information Processing Signal transduction hsa04020 Calcium signaling pathway 2/69 254/9376 1.06995321237019 FLT1/CD38 0.0973161263951877 Metabolism Global and overview maps hsa01200 Carbon metabolism 1/69 116/9376 1.17141429285357 FBP1 0.159946911799501 Human Diseases Neurodegenerative disease hsa05012 Parkinson disease 2/69 268/9376 1.01406013411205 UBC/TXN 0.0201071573184818 Environmental Information Processing Signal transduction hsa04152 AMPK signaling pathway 1/69 122/9376 1.11380375386077 FBP1 0.108937419124882 Human Diseases Neurodegenerative disease hsa05020 Prion disease 2/69 275/9376 0.988247694334651 CYBA/CYBB -0.0170313939569868 Environmental Information Processing Signal transduction hsa04068 FoxO signaling pathway 1/69 133/9376 1.02168464639861 TNFSF10 0.0216858782538625 Cellular Processes Cell growth and death hsa04210 Apoptosis 1/69 137/9376 0.991854437744631 TNFSF10 -0.00826940369725905 Metabolism Energy metabolism hsa00190 Oxidative phosphorylation 1/69 138/9376 0.984667086746482 PPA1 -0.0156235805023261 Human Diseases Infectious disease: bacterial hsa05135 Yersinia infection 1/69 138/9376 0.984667086746482 FN1 -0.0156235805023261 Organismal Systems Endocrine system hsa04915 Estrogen signaling pathway 1/69 139/9376 0.977583150870608 KRT19 -0.0229256587623988 Environmental Information Processing Signal transduction hsa04371 Apelin signaling pathway 1/69 140/9376 0.970600414078675 SERPINE1 -0.0301764811655356 Genetic Information Processing Folding, sorting and degradation hsa04120 Ubiquitin mediated proteolysis 1/69 142/9376 0.95692998571137 UBC -0.0445276299261388 Environmental Information Processing Signal transduction hsa04010 MAPK signaling pathway 2/69 300/9376 0.905893719806763 FLT1/IGF2 -0.142638682066633 Human Diseases Endocrine and metabolic disease hsa04936 Alcoholic liver disease 1/69 144/9376 0.943639291465379 C2 -0.058683379848359 Metabolism Global and overview maps hsa01240 Biosynthesis of cofactors 1/69 154/9376 0.882364012798795 IDO1 -0.126734054616601 Organismal Systems Circulatory system hsa04261 Adrenergic signaling in cardiomyocytes 1/69 154/9376 0.882364012798795 TPM1 -0.126734054616601 Organismal Systems Endocrine system hsa04921 Oxytocin signaling pathway 1/69 154/9376 0.882364012798795 CD38 -0.126734054616601 Cellular Processes Cell growth and death hsa04110 Cell cycle 1/69 158/9376 0.860025683360851 CDKN1C -0.152779074245753 Human Diseases Cancer: overview hsa05206 MicroRNAs in cancer 2/69 323/9376 0.841387355857675 TIMP3/TPM1 -0.249774519776178 Cellular Processes Transport and catabolism hsa04140 Autophagy - animal 1/69 169/9376 0.804047680301861 UBC -0.221329863611815 Human Diseases Cancer: specific types hsa05225 Hepatocellular carcinoma 1/69 170/9376 0.799317988064791 IGF2 -0.227354077978383 Environmental Information Processing Signal transduction hsa04310 Wnt signaling pathway 1/69 178/9376 0.763393584106823 NOTUM -0.274406972343556 Cellular Processes Cell motility hsa04814 Motor proteins 1/69 194/9376 0.700433288510384 TPM1 -0.363020457118155 NA NA hsa04082 Neuroactive ligand signaling 1/69 199/9376 0.682834462165902 TAC3 -0.38937448640813 Human Diseases Infectious disease: bacterial hsa05130 Pathogenic Escherichia coli infection 1/69 200/9376 0.679420289855073 TNFSF10 -0.39457508059137 NA NA hsa04519 Cadherin signaling 2/69 404/9376 0.672693356292151 KRT19/KRT7 -0.579036842386627 Human Diseases Cancer: overview hsa05208 Chemical carcinogenesis - reactive oxygen species 1/69 227/9376 0.598608184894337 CYBA -0.527108420200581 Cellular Processes Transport and catabolism hsa04142 Lysosome biogenesis 1/69 250/9376 0.543536231884058 SLC2A6 -0.629856201559159 Human Diseases Neurodegenerative disease hsa05022 Pathways of neurodegeneration - multiple diseases 2/69 480/9376 0.566183574879227 UBC/CYBB -0.840106895556487 Human Diseases Neurodegenerative disease hsa05014 Amyotrophic lateral sclerosis 1/69 368/9376 0.369250157529931 PFN1 -1.06285054096063 Environmental Information Processing Signaling molecules and interaction hsa04080 Neuroactive ligand-receptor interaction 1/69 370/9376 0.367254210732472 TAC3 -1.06922592680791 Human Diseases Neurodegenerative disease hsa05010 Alzheimer disease 1/69 388/9376 0.350216644255192 CYBB -1.12553301918381