ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0003823 antigen binding 11/101 174/18639 0.0632183908045977 11.6666097644247 2.62501882649878e-09 8.03255760908626e-07 GO:0061134 peptidase regulator activity 9/101 226/18639 0.0398230088495575 7.34911942521686 3.83636010868068e-06 0.00033304512639799 GO:0042605 peptide antigen binding 5/101 45/18639 0.111111111111111 20.5049504950495 4.34944266047732e-06 0.00033304512639799 GO:0008201 heparin binding 8/101 172/18639 0.0465116279069767 8.58346764909049 4.35353106402601e-06 0.00033304512639799 GO:0061135 endopeptidase regulator activity 8/101 184/18639 0.0434782608695652 8.02367628067154 7.15768812349276e-06 0.00042891430811015 GO:0042277 peptide binding 9/101 249/18639 0.036144578313253 6.67028510079924 8.41008447274804e-06 0.00042891430811015 GO:1901681 sulfur compound binding 9/101 275/18639 0.0327272727272727 6.0396399639964 1.85690749174367e-05 0.000811733846390803 GO:0004866 endopeptidase inhibitor activity 7/101 161/18639 0.0434782608695652 8.02367628067154 2.7422257953493e-05 0.00104890136672111 GO:0005201 extracellular matrix structural constituent 7/101 168/18639 0.0416666666666667 7.68935643564356 3.60181404114176e-05 0.00114472663311091 GO:0030414 peptidase inhibitor activity 7/101 169/18639 0.0414201183431953 7.6438572851368 3.74093670951278e-05 0.00114472663311091 GO:0023023 MHC protein complex binding 4/101 37/18639 0.108108108108108 19.950762643832 4.67512537222353e-05 0.00130053487627309 GO:0005539 glycosaminoglycan binding 8/101 242/18639 0.0330578512396694 6.10064642827919 5.14356078586508e-05 0.0013116080003956 GO:0061791 GTPase motor activity 4/101 40/18639 0.1 18.4544554455446 6.3891014079694e-05 0.0013964750220276 GO:1990606 membrane scission GTPase motor activity 4/101 40/18639 0.1 18.4544554455446 6.3891014079694e-05 0.0013964750220276 GO:0045236 CXCR chemokine receptor binding 3/101 17/18639 0.176470588235294 32.5666860803727 9.93745204441303e-05 0.00202724021706026 GO:0034987 immunoglobulin receptor binding 3/101 19/18639 0.157894736842105 29.1386138613861 0.000140497488870058 0.00268701447463985 GO:0140375 immune receptor activity 6/101 156/18639 0.0384615384615385 7.0978674790556 0.000205557531845776 0.00370003557322396 GO:0023026 MHC class II protein complex binding 3/101 27/18639 0.111111111111111 20.5049504950495 0.000410961185088565 0.00698634014650561 GO:0042379 chemokine receptor binding 4/101 72/18639 0.0555555555555556 10.2524752475248 0.000629909555381609 0.0101448591550933 GO:0005126 cytokine receptor binding 7/101 275/18639 0.0254545454545455 4.69749774977498 0.000744757265509756 0.0113947861622993 GO:0030246 carbohydrate binding 7/101 280/18639 0.025 4.61361386138614 0.000827697221821893 0.0120607309465476 GO:0001540 amyloid-beta binding 4/101 83/18639 0.0481927710843374 8.89371346773232 0.0010751558937736 0.0149544410679419 GO:0016175 superoxide-generating NAD(P)H oxidase activity 2/101 10/18639 0.2 36.9089108910891 0.00127175585797388 0.0169198822843482 GO:0042287 MHC protein binding 3/101 41/18639 0.0731707317073171 13.5032600821058 0.00141765431976409 0.0180750925769921 GO:0005125 cytokine activity 6/101 234/18639 0.0256410256410256 4.73191165270373 0.00172515855803269 0.0201338550729042 GO:0004867 serine-type endopeptidase inhibitor activity 4/101 95/18639 0.0421052631578947 7.77029702970297 0.00177269160113958 0.0201338550729042 GO:0004896 cytokine receptor activity 4/101 96/18639 0.0416666666666667 7.68935643564356 0.00184215935595697 0.0201338550729042 GO:0008009 chemokine activity 3/101 45/18639 0.0666666666666667 12.3029702970297 0.00185777093920903 0.0201338550729042 GO:0004857 enzyme inhibitor activity 8/101 416/18639 0.0192307692307692 3.5489337395278 0.00190811044808569 0.0201338550729042 GO:0033218 amide binding 6/101 247/18639 0.0242914979757085 4.48286367098248 0.00226361500592041 0.0230888730603882 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 2/101 16/18639 0.125 23.0680693069307 0.00332022615291316 0.0317496625872321 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 2/101 16/18639 0.125 23.0680693069307 0.00332022615291316 0.0317496625872321 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 2/101 20/18639 0.1 18.4544554455446 0.00518341644635693 0.0466507480172123 GO:0042288 MHC class I protein binding 2/101 20/18639 0.1 18.4544554455446 0.00518341644635693 0.0466507480172123 GO:0030021 extracellular matrix structural constituent conferring compression resistance 2/101 22/18639 0.0909090909090909 16.7767776777678 0.00625772283264518 0.0545277509855016 GO:0019838 growth factor binding 4/101 136/18639 0.0294117647058824 5.42778101339546 0.00641502952770607 0.0545277509855016 GO:0005518 collagen binding 3/101 72/18639 0.0416666666666667 7.68935643564356 0.00702738607730874 0.0581183821528777 GO:0019955 cytokine binding 4/101 144/18639 0.0277777777777778 5.12623762376238 0.0078227369639176 0.0629936187094417 GO:0003774 cytoskeletal motor activity 4/101 153/18639 0.0261437908496732 4.8246942341293 0.00963349716120135 0.0755859008032721 GO:0003785 actin monomer binding 2/101 29/18639 0.0689655172413793 12.7272106520997 0.0107311648031258 0.0820934107439127 GO:0005178 integrin binding 4/101 161/18639 0.0248447204968944 4.58495787466945 0.0114552134624818 0.0834754099747477 GO:0001968 fibronectin binding 2/101 30/18639 0.0666666666666667 12.3029702970297 0.0114574092122203 0.0834754099747477 GO:0005164 tumor necrosis factor receptor binding 2/101 31/18639 0.0645161290322581 11.9061002874481 0.0122046996785874 0.0868520488755286 GO:0043425 bHLH transcription factor binding 2/101 32/18639 0.0625 11.5340346534653 0.0129727914966256 0.0902198681356231 GO:0030296 protein tyrosine kinase activator activity 2/101 33/18639 0.0606060606060606 11.1845184518452 0.0137614419486476 0.093577805250804 GO:0015035 protein-disulfide reductase activity 2/101 34/18639 0.0588235294117647 10.8555620267909 0.0145704102908725 0.096924903239282 GO:0043394 proteoglycan binding 2/101 37/18639 0.0540540540540541 9.97538132191598 0.0171168445379116 0.111441583587254 GO:0015036 disulfide oxidoreductase activity 2/101 40/18639 0.05 9.22722772277228 0.01983765961068 0.126465080018085 GO:0008307 structural constituent of muscle 2/101 42/18639 0.0476190476190476 8.78783592644979 0.0217453522719367 0.135797506024747 GO:0001664 G protein-coupled receptor binding 5/101 297/18639 0.0168350168350168 3.10681068106811 0.0227820535442679 0.138027059344671 GO:0005200 structural constituent of cytoskeleton 3/101 112/18639 0.0267857142857143 4.94315770862801 0.0230045098907785 0.138027059344671 GO:0009055 electron transfer activity 3/101 116/18639 0.0258620689655172 4.77270399453738 0.0251915603363447 0.148242643517721 GO:0038187 pattern recognition receptor activity 2/101 48/18639 0.0416666666666667 7.68935643564356 0.0278991093519031 0.161077876635516 GO:0032813 tumor necrosis factor receptor superfamily binding 2/101 50/18639 0.04 7.38178217821782 0.0300881284609184 0.170499394611871 GO:0016860 intramolecular oxidoreductase activity 2/101 53/18639 0.0377358490566038 6.96394545114889 0.0334949985261851 0.18635399180023 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 2/101 54/18639 0.037037037037037 6.83498349834983 0.0346626880468714 0.189406831113262 GO:0002020 protease binding 3/101 136/18639 0.0220588235294118 4.07083576004659 0.0377444029685225 0.20184984962119 GO:0016504 peptidase activator activity 2/101 57/18639 0.0350877192982456 6.47524752475248 0.0382591218236242 0.20184984962119 GO:0020037 heme binding 3/101 142/18639 0.0211267605633803 3.89882861525589 0.0420290318878069 0.217981080638456 GO:0015026 coreceptor activity 2/101 61/18639 0.0327868852459016 6.05064112968674 0.0432648356600341 0.220650661866174 GO:0046906 tetrapyrrole binding 3/101 152/18639 0.0197368421052632 3.64232673267327 0.0496889330087613 0.221973808120695 GO:0019887 protein kinase regulator activity 4/101 255/18639 0.0156862745098039 2.89481654047758 0.0499768388473558 0.221973808120695 GO:0003796 lysozyme activity 1/101 10/18639 0.1 18.4544554455446 0.0528975057215004 0.221973808120695 GO:0004382 GDP phosphatase activity 1/101 10/18639 0.1 18.4544554455446 0.0528975057215004 0.221973808120695 GO:0004955 prostaglandin receptor activity 1/101 10/18639 0.1 18.4544554455446 0.0528975057215004 0.221973808120695 GO:0005528 FK506 binding 1/101 10/18639 0.1 18.4544554455446 0.0528975057215004 0.221973808120695 GO:0032395 MHC class II receptor activity 1/101 10/18639 0.1 18.4544554455446 0.0528975057215004 0.221973808120695 GO:0043295 glutathione binding 1/101 10/18639 0.1 18.4544554455446 0.0528975057215004 0.221973808120695 GO:0050308 sugar-phosphatase activity 1/101 10/18639 0.1 18.4544554455446 0.0528975057215004 0.221973808120695 GO:0001851 complement component C3b binding 1/101 11/18639 0.0909090909090909 16.7767776777678 0.0580323681361294 0.221973808120695 GO:0003953 NAD+ nucleosidase activity 1/101 11/18639 0.0909090909090909 16.7767776777678 0.0580323681361294 0.221973808120695 GO:0004954 prostanoid receptor activity 1/101 11/18639 0.0909090909090909 16.7767776777678 0.0580323681361294 0.221973808120695 GO:0008199 ferric iron binding 1/101 11/18639 0.0909090909090909 16.7767776777678 0.0580323681361294 0.221973808120695 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 1/101 11/18639 0.0909090909090909 16.7767776777678 0.0580323681361294 0.221973808120695 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 1/101 11/18639 0.0909090909090909 16.7767776777678 0.0580323681361294 0.221973808120695 GO:0019203 carbohydrate phosphatase activity 1/101 11/18639 0.0909090909090909 16.7767776777678 0.0580323681361294 0.221973808120695 GO:0042608 T cell receptor binding 1/101 11/18639 0.0909090909090909 16.7767776777678 0.0580323681361294 0.221973808120695 GO:0048185 activin binding 1/101 11/18639 0.0909090909090909 16.7767776777678 0.0580323681361294 0.221973808120695 GO:0050998 nitric-oxide synthase binding 1/101 11/18639 0.0909090909090909 16.7767776777678 0.0580323681361294 0.221973808120695 GO:1900750 oligopeptide binding 1/101 11/18639 0.0909090909090909 16.7767776777678 0.0580323681361294 0.221973808120695 GO:0048029 monosaccharide binding 2/101 74/18639 0.027027027027027 4.98769066095799 0.0610551790406002 0.227302794934994 GO:0004126 cytidine deaminase activity 1/101 12/18639 0.0833333333333333 15.3787128712871 0.0631396652597206 0.227302794934994 GO:0005527 macrolide binding 1/101 12/18639 0.0833333333333333 15.3787128712871 0.0631396652597206 0.227302794934994 GO:0008603 cAMP-dependent protein kinase regulator activity 1/101 12/18639 0.0833333333333333 15.3787128712871 0.0631396652597206 0.227302794934994 GO:0016208 AMP binding 1/101 12/18639 0.0833333333333333 15.3787128712871 0.0631396652597206 0.227302794934994 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 1/101 13/18639 0.0769230769230769 14.1957349581112 0.0682195435980881 0.237217958420625 GO:0031994 insulin-like growth factor I binding 1/101 13/18639 0.0769230769230769 14.1957349581112 0.0682195435980881 0.237217958420625 GO:0032396 inhibitory MHC class I receptor activity 1/101 13/18639 0.0769230769230769 14.1957349581112 0.0682195435980881 0.237217958420625 GO:0019207 kinase regulator activity 4/101 287/18639 0.0139372822299652 2.57204953944872 0.0707488946640947 0.242615991031953 GO:0005545 1-phosphatidylinositol binding 1/101 14/18639 0.0714285714285714 13.1817538896747 0.0732721488862114 0.242615991031953 GO:0008191 metalloendopeptidase inhibitor activity 1/101 14/18639 0.0714285714285714 13.1817538896747 0.0732721488862114 0.242615991031953 GO:0061783 peptidoglycan muralytic activity 1/101 14/18639 0.0714285714285714 13.1817538896747 0.0732721488862114 0.242615991031953 GO:0016853 isomerase activity 3/101 180/18639 0.0166666666666667 3.07574257425743 0.0744306260649899 0.242615991031953 GO:0000774 adenyl-nucleotide exchange factor activity 1/101 15/18639 0.0666666666666667 12.3029702970297 0.0782976260922511 0.242615991031953 GO:0004953 icosanoid receptor activity 1/101 15/18639 0.0666666666666667 12.3029702970297 0.0782976260922511 0.242615991031953 GO:0031386 protein tag activity 1/101 15/18639 0.0666666666666667 12.3029702970297 0.0782976260922511 0.242615991031953 GO:0141047 molecular tag activity 1/101 15/18639 0.0666666666666667 12.3029702970297 0.0782976260922511 0.242615991031953 GO:0008237 metallopeptidase activity 3/101 184/18639 0.016304347826087 3.00887860525183 0.0783401594657539 0.242615991031953 GO:0016209 antioxidant activity 2/101 86/18639 0.0232558139534884 4.29173382454525 0.0792862715790698 0.242615991031953 GO:0050660 flavin adenine dinucleotide binding 2/101 86/18639 0.0232558139534884 4.29173382454525 0.0792862715790698 0.242615991031953 GO:0016651 oxidoreductase activity, acting on NAD(P)H 2/101 88/18639 0.0227272727272727 4.19419441944194 0.0824727946800324 0.242748690885634 GO:0005159 insulin-like growth factor receptor binding 1/101 16/18639 0.0625 11.5340346534653 0.083296119421541 0.242748690885634 GO:0005521 lamin binding 1/101 16/18639 0.0625 11.5340346534653 0.083296119421541 0.242748690885634 GO:0016722 oxidoreductase activity, acting on metal ions 1/101 16/18639 0.0625 11.5340346534653 0.083296119421541 0.242748690885634 GO:0061809 NAD+ nucleosidase activity, cyclic ADP-ribose generating 1/101 16/18639 0.0625 11.5340346534653 0.083296119421541 0.242748690885634 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 1/101 17/18639 0.0588235294117647 10.8555620267909 0.0882677723205592 0.243332777748568 GO:0017110 nucleoside diphosphate phosphatase activity 1/101 17/18639 0.0588235294117647 10.8555620267909 0.0882677723205592 0.243332777748568 GO:0019198 transmembrane receptor protein phosphatase activity 1/101 17/18639 0.0588235294117647 10.8555620267909 0.0882677723205592 0.243332777748568 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 1/101 17/18639 0.0588235294117647 10.8555620267909 0.0882677723205592 0.243332777748568 GO:0048038 quinone binding 1/101 17/18639 0.0588235294117647 10.8555620267909 0.0882677723205592 0.243332777748568 GO:0070403 NAD+ binding 1/101 17/18639 0.0588235294117647 10.8555620267909 0.0882677723205592 0.243332777748568 GO:0032393 MHC class I receptor activity 1/101 18/18639 0.0555555555555556 10.2524752475248 0.0932127274808873 0.252416766452668 GO:0070064 proline-rich region binding 1/101 18/18639 0.0555555555555556 10.2524752475248 0.0932127274808873 0.252416766452668 GO:0044389 ubiquitin-like protein ligase binding 4/101 322/18639 0.0124223602484472 2.29247893733473 0.09777739307351 0.256650639435892 GO:0003756 protein disulfide isomerase activity 1/101 19/18639 0.0526315789473684 9.71287128712871 0.0981311268431353 0.256650639435892 GO:0005520 insulin-like growth factor binding 1/101 19/18639 0.0526315789473684 9.71287128712871 0.0981311268431353 0.256650639435892 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 1/101 19/18639 0.0526315789473684 9.71287128712871 0.0981311268431353 0.256650639435892 GO:0003924 GTPase activity 4/101 331/18639 0.0120845921450151 2.23014567317759 0.105413085174151 0.272842806566638 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 1/101 21/18639 0.0476190476190476 8.78783592644979 0.107888822204455 0.272842806566638 GO:0001846 opsonin binding 1/101 21/18639 0.0476190476190476 8.78783592644979 0.107888822204455 0.272842806566638 GO:0072542 protein phosphatase activator activity 1/101 21/18639 0.0476190476190476 8.78783592644979 0.107888822204455 0.272842806566638 GO:0061133 endopeptidase activator activity 1/101 22/18639 0.0454545454545455 8.38838883888389 0.112728398365017 0.282744999177829 GO:0004602 glutathione peroxidase activity 1/101 23/18639 0.0434782608695652 8.02367628067154 0.117541979058208 0.286095084429068 GO:0005158 insulin receptor binding 1/101 23/18639 0.0434782608695652 8.02367628067154 0.117541979058208 0.286095084429068 GO:0016849 phosphorus-oxygen lyase activity 1/101 23/18639 0.0434782608695652 8.02367628067154 0.117541979058208 0.286095084429068 GO:0004222 metalloendopeptidase activity 2/101 110/18639 0.0181818181818182 3.35535553555356 0.119844074154915 0.286095084429068 GO:0015149 hexose transmembrane transporter activity 1/101 24/18639 0.0416666666666667 7.68935643564356 0.122329702528079 0.286095084429068 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 1/101 24/18639 0.0416666666666667 7.68935643564356 0.122329702528079 0.286095084429068 GO:0035035 histone acetyltransferase binding 1/101 24/18639 0.0416666666666667 7.68935643564356 0.122329702528079 0.286095084429068 GO:0055056 D-glucose transmembrane transporter activity 1/101 24/18639 0.0416666666666667 7.68935643564356 0.122329702528079 0.286095084429068 GO:0001848 complement binding 1/101 25/18639 0.04 7.38178217821782 0.127091706290886 0.286095084429068 GO:0005537 D-mannose binding 1/101 25/18639 0.04 7.38178217821782 0.127091706290886 0.286095084429068 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 1/101 25/18639 0.04 7.38178217821782 0.127091706290886 0.286095084429068 GO:0019211 phosphatase activator activity 1/101 25/18639 0.04 7.38178217821782 0.127091706290886 0.286095084429068 GO:0008157 protein phosphatase 1 binding 1/101 26/18639 0.0384615384615385 7.0978674790556 0.131828127138884 0.286095084429068 GO:0008198 ferrous iron binding 1/101 26/18639 0.0384615384615385 7.0978674790556 0.131828127138884 0.286095084429068 GO:0015145 monosaccharide transmembrane transporter activity 1/101 26/18639 0.0384615384615385 7.0978674790556 0.131828127138884 0.286095084429068 GO:0030247 polysaccharide binding 1/101 26/18639 0.0384615384615385 7.0978674790556 0.131828127138884 0.286095084429068 GO:0030507 spectrin binding 1/101 26/18639 0.0384615384615385 7.0978674790556 0.131828127138884 0.286095084429068 GO:0050750 low-density lipoprotein particle receptor binding 1/101 26/18639 0.0384615384615385 7.0978674790556 0.131828127138884 0.286095084429068 GO:0070006 metalloaminopeptidase activity 1/101 26/18639 0.0384615384615385 7.0978674790556 0.131828127138884 0.286095084429068 GO:0004364 glutathione transferase activity 1/101 27/18639 0.037037037037037 6.83498349834983 0.136539101144094 0.294232147535864 GO:0051119 sugar transmembrane transporter activity 1/101 28/18639 0.0357142857142857 6.59087694483734 0.141224763662063 0.302201242521618 GO:0004629 phospholipase C activity 1/101 29/18639 0.0344827586206897 6.36360532604985 0.145885249335597 0.307868181356501 GO:0051861 glycolipid binding 1/101 29/18639 0.0344827586206897 6.36360532604985 0.145885249335597 0.307868181356501 GO:0005525 GTP binding 4/101 378/18639 0.0105820105820106 1.95285242809995 0.149387090102615 0.313098969667125 GO:0051721 protein phosphatase 2A binding 1/101 30/18639 0.0333333333333333 6.15148514851485 0.150520692098472 0.313328787633553 GO:0070325 lipoprotein particle receptor binding 1/101 31/18639 0.032258064516129 5.95305014372405 0.155131225179134 0.320744289897399 GO:0016798 hydrolase activity, acting on glycosyl bonds 2/101 130/18639 0.0153846153846154 2.83914699162224 0.15669759239399 0.321808478339335 GO:0031072 heat shock protein binding 2/101 131/18639 0.0152671755725191 2.8174741138236 0.158594373398721 0.32353252173339 GO:0019239 deaminase activity 1/101 33/18639 0.0303030303030303 5.59225922592259 0.164278091702993 0.330717737244184 GO:0140416 transcription regulator inhibitor activity 1/101 33/18639 0.0303030303030303 5.59225922592259 0.164278091702993 0.330717737244184 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 1/101 34/18639 0.0294117647058824 5.42778101339546 0.168814688109421 0.335436977671967 GO:0090482 vitamin transmembrane transporter activity 1/101 34/18639 0.0294117647058824 5.42778101339546 0.168814688109421 0.335436977671967 GO:0019001 guanyl nucleotide binding 4/101 400/18639 0.01 1.84544554455446 0.17206911458927 0.337520186309722 GO:0032561 guanyl ribonucleotide binding 4/101 400/18639 0.01 1.84544554455446 0.17206911458927 0.337520186309722 GO:0030295 protein kinase activator activity 2/101 139/18639 0.0143884892086331 2.65531733029418 0.173917409592681 0.337958676935478 GO:0004175 endopeptidase activity 4/101 405/18639 0.00987654320987654 1.82266226622662 0.177386652145901 0.337958676935478 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 1/101 36/18639 0.0277777777777778 5.12623762376238 0.177814859433372 0.337958676935478 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 1/101 36/18639 0.0277777777777778 5.12623762376238 0.177814859433372 0.337958676935478 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 1/101 36/18639 0.0277777777777778 5.12623762376238 0.177814859433372 0.337958676935478 GO:0030280 structural constituent of skin epidermis 1/101 37/18639 0.027027027027027 4.98769066095799 0.182278693180469 0.344304198229774 GO:0019903 protein phosphatase binding 2/101 144/18639 0.0138888888888889 2.56311881188119 0.183613867368013 0.344698425856516 GO:0043531 ADP binding 1/101 38/18639 0.0263157894736842 4.85643564356436 0.186718530401669 0.348389453066529 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 1/101 39/18639 0.0256410256410256 4.73191165270373 0.191134498813552 0.349889929770131 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 1/101 39/18639 0.0256410256410256 4.73191165270373 0.191134498813552 0.349889929770131 GO:0019209 kinase activator activity 2/101 148/18639 0.0135135135135135 2.49384533047899 0.191427739617838 0.349889929770131 GO:0004177 aminopeptidase activity 1/101 40/18639 0.025 4.61361386138614 0.195526725459779 0.349889929770131 GO:0015144 carbohydrate transmembrane transporter activity 1/101 40/18639 0.025 4.61361386138614 0.195526725459779 0.349889929770131 GO:0071855 neuropeptide receptor binding 1/101 40/18639 0.025 4.61361386138614 0.195526725459779 0.349889929770131 GO:0071949 FAD binding 1/101 40/18639 0.025 4.61361386138614 0.195526725459779 0.349889929770131 GO:0001530 lipopolysaccharide binding 1/101 41/18639 0.024390243902439 4.50108669403526 0.199895336714608 0.353572098466302 GO:0042169 SH2 domain binding 1/101 41/18639 0.024390243902439 4.50108669403526 0.199895336714608 0.353572098466302 GO:0016859 cis-trans isomerase activity 1/101 42/18639 0.0238095238095238 4.39391796322489 0.204240458286381 0.355099887702457 GO:0042056 chemoattractant activity 1/101 42/18639 0.0238095238095238 4.39391796322489 0.204240458286381 0.355099887702457 GO:0051879 Hsp90 protein binding 1/101 42/18639 0.0238095238095238 4.39391796322489 0.204240458286381 0.355099887702457 GO:0001046 core promoter sequence-specific DNA binding 1/101 44/18639 0.0227272727272727 4.19419441944194 0.212860731905375 0.355513293159947 GO:0001223 transcription coactivator binding 1/101 44/18639 0.0227272727272727 4.19419441944194 0.212860731905375 0.355513293159947 GO:0008083 growth factor activity 2/101 162/18639 0.0123456790123457 2.27832783278328 0.219089620095388 0.355513293159947 GO:0003779 actin binding 4/101 443/18639 0.0090293453724605 1.66631651878506 0.219496623406151 0.355513293159947 GO:0004180 carboxypeptidase activity 1/101 46/18639 0.0217391304347826 4.01183814033577 0.221388538796751 0.355513293159947 GO:0030291 protein serine/threonine kinase inhibitor activity 1/101 46/18639 0.0217391304347826 4.01183814033577 0.221388538796751 0.355513293159947 GO:0031625 ubiquitin protein ligase binding 3/101 302/18639 0.00993377483443709 1.83322405088191 0.225049770386044 0.355513293159947 GO:0001784 phosphotyrosine residue binding 1/101 47/18639 0.0212765957446809 3.92647988203076 0.2256180745135 0.355513293159947 GO:0005504 fatty acid binding 1/101 47/18639 0.0212765957446809 3.92647988203076 0.2256180745135 0.355513293159947 GO:0140359 ABC-type transporter activity 1/101 47/18639 0.0212765957446809 3.92647988203076 0.2256180745135 0.355513293159947 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 1/101 48/18639 0.0208333333333333 3.84467821782178 0.2298248610063 0.355513293159947 GO:0001222 transcription corepressor binding 1/101 49/18639 0.0204081632653061 3.76621539704991 0.234009019418347 0.355513293159947 GO:0005004 GPI-linked ephrin receptor activity 1/101 49/18639 0.0204081632653061 3.76621539704991 0.234009019418347 0.355513293159947 GO:0005008 hepatocyte growth factor receptor activity 1/101 49/18639 0.0204081632653061 3.76621539704991 0.234009019418347 0.355513293159947 GO:0005009 insulin receptor activity 1/101 49/18639 0.0204081632653061 3.76621539704991 0.234009019418347 0.355513293159947 GO:0005011 macrophage colony-stimulating factor receptor activity 1/101 49/18639 0.0204081632653061 3.76621539704991 0.234009019418347 0.355513293159947 GO:0005018 platelet-derived growth factor alpha-receptor activity 1/101 49/18639 0.0204081632653061 3.76621539704991 0.234009019418347 0.355513293159947 GO:0005020 stem cell factor receptor activity 1/101 49/18639 0.0204081632653061 3.76621539704991 0.234009019418347 0.355513293159947 GO:0008288 boss receptor activity 1/101 49/18639 0.0204081632653061 3.76621539704991 0.234009019418347 0.355513293159947 GO:0016763 pentosyltransferase activity 1/101 49/18639 0.0204081632653061 3.76621539704991 0.234009019418347 0.355513293159947 GO:0036332 placental growth factor receptor activity 1/101 49/18639 0.0204081632653061 3.76621539704991 0.234009019418347 0.355513293159947 GO:0038062 protein tyrosine kinase collagen receptor activity 1/101 49/18639 0.0204081632653061 3.76621539704991 0.234009019418347 0.355513293159947 GO:0060175 brain-derived neurotrophic factor receptor activity 1/101 49/18639 0.0204081632653061 3.76621539704991 0.234009019418347 0.355513293159947 GO:0060590 ATPase regulator activity 1/101 49/18639 0.0204081632653061 3.76621539704991 0.234009019418347 0.355513293159947 GO:0005006 epidermal growth factor receptor activity 1/101 50/18639 0.02 3.69089108910891 0.238170670254213 0.355513293159947 GO:0005007 fibroblast growth factor receptor activity 1/101 50/18639 0.02 3.69089108910891 0.238170670254213 0.355513293159947 GO:0005017 platelet-derived growth factor receptor activity 1/101 50/18639 0.02 3.69089108910891 0.238170670254213 0.355513293159947 GO:0005019 platelet-derived growth factor beta-receptor activity 1/101 50/18639 0.02 3.69089108910891 0.238170670254213 0.355513293159947 GO:0048020 CCR chemokine receptor binding 1/101 50/18639 0.02 3.69089108910891 0.238170670254213 0.355513293159947 GO:0005010 insulin-like growth factor receptor activity 1/101 51/18639 0.0196078431372549 3.61852067559697 0.242309933383178 0.356475190457944 GO:0005021 vascular endothelial growth factor receptor activity 1/101 51/18639 0.0196078431372549 3.61852067559697 0.242309933383178 0.356475190457944 GO:0005030 neurotrophin receptor activity 1/101 51/18639 0.0196078431372549 3.61852067559697 0.242309933383178 0.356475190457944 GO:0004252 serine-type endopeptidase activity 2/101 176/18639 0.0113636363636364 2.09709720972097 0.247073538815804 0.361602181553425 GO:0005003 ephrin receptor activity 1/101 53/18639 0.0188679245283019 3.48197272557444 0.250521772840935 0.361602181553425 GO:0005005 transmembrane-ephrin receptor activity 1/101 53/18639 0.0188679245283019 3.48197272557444 0.250521772840935 0.361602181553425 GO:0038064 collagen receptor activity 1/101 53/18639 0.0188679245283019 3.48197272557444 0.250521772840935 0.361602181553425 GO:0003925 G protein activity 1/101 54/18639 0.0185185185185185 3.41749174917492 0.254594585761578 0.364046463752536 GO:0051287 NAD binding 1/101 54/18639 0.0185185185185185 3.41749174917492 0.254594585761578 0.364046463752536 GO:0140313 molecular sequestering activity 1/101 55/18639 0.0181818181818182 3.35535553555356 0.258645484165564 0.368118689091454 GO:1901981 phosphatidylinositol phosphate binding 2/101 185/18639 0.0108108108108108 1.9950762643832 0.265142129248143 0.375618016434869 GO:0004601 peroxidase activity 1/101 57/18639 0.0175438596491228 3.23762376237624 0.266682003776732 0.376058493804977 GO:0140297 DNA-binding transcription factor binding 4/101 488/18639 0.00819672131147541 1.51266028242168 0.272393810993842 0.379310440978458 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 1/101 59/18639 0.0169491525423729 3.12787380432959 0.27463225824348 0.379310440978458 GO:0045309 protein phosphorylated amino acid binding 1/101 59/18639 0.0169491525423729 3.12787380432959 0.27463225824348 0.379310440978458 GO:0070888 E-box binding 1/101 59/18639 0.0169491525423729 3.12787380432959 0.27463225824348 0.379310440978458 GO:0019902 phosphatase binding 2/101 190/18639 0.0105263157894737 1.94257425742574 0.275186006200058 0.379310440978458 GO:0004714 transmembrane receptor protein tyrosine kinase activity 1/101 60/18639 0.0166666666666667 3.07574257425743 0.278575322932253 0.38226030859762 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 1/101 61/18639 0.0163934426229508 3.02532056484337 0.28249716438679 0.38517610177642 GO:0008236 serine-type peptidase activity 2/101 194/18639 0.0103092783505155 1.90252117995305 0.283217721894427 0.38517610177642 GO:0005507 copper ion binding 1/101 63/18639 0.0158730158730159 2.92927864214993 0.290277629381115 0.392600134327723 GO:0017171 serine hydrolase activity 2/101 198/18639 0.0101010101010101 1.86408640864086 0.291242583308474 0.392600134327723 GO:0038024 cargo receptor activity 1/101 65/18639 0.0153846153846154 2.83914699162224 0.297974550854848 0.399913212989402 GO:0008235 metalloexopeptidase activity 1/101 66/18639 0.0151515151515152 2.7961296129613 0.301791960694606 0.403267860142137 GO:0016500 protein-hormone receptor activity 1/101 67/18639 0.0149253731343284 2.7543963351559 0.305588816989757 0.404805965363055 GO:0050840 extracellular matrix binding 1/101 67/18639 0.0149253731343284 2.7543963351559 0.305588816989757 0.404805965363055 GO:0030145 manganese ion binding 1/101 68/18639 0.0147058823529412 2.71389050669773 0.309365229303134 0.406290816166348 GO:1990841 promoter-specific chromatin binding 1/101 68/18639 0.0147058823529412 2.71389050669773 0.309365229303134 0.406290816166348 GO:0042578 phosphoric ester hydrolase activity 3/101 363/18639 0.00826446280991736 1.5251616070698 0.314256774161204 0.410951166210805 GO:0097110 scaffold protein binding 1/101 70/18639 0.0142857142857143 2.63635077793494 0.316857157348073 0.412588468717065 GO:0046982 protein heterodimerization activity 3/101 369/18639 0.00813008130081301 1.50036223134509 0.323166825612418 0.419021392531356 GO:0043539 protein serine/threonine kinase activator activity 1/101 73/18639 0.0136986301369863 2.52800759528008 0.327944425539449 0.423421916519289 GO:0019003 GDP binding 1/101 75/18639 0.0133333333333333 2.46059405940594 0.335236766627483 0.42921527442682 GO:0044183 protein folding chaperone 1/101 75/18639 0.0133333333333333 2.46059405940594 0.335236766627483 0.42921527442682 GO:0019199 transmembrane receptor protein kinase activity 1/101 78/18639 0.0128205128205128 2.36595582635187 0.34602862773239 0.441186500358797 GO:0033293 monocarboxylic acid binding 1/101 79/18639 0.0126582278481013 2.33600701842336 0.349587224176495 0.443874234846504 GO:0004860 protein kinase inhibitor activity 1/101 84/18639 0.0119047619047619 2.19695898161245 0.367094641785162 0.462267326692427 GO:0051117 ATPase binding 1/101 84/18639 0.0119047619047619 2.19695898161245 0.367094641785162 0.462267326692427 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 1/101 86/18639 0.0116279069767442 2.14586691227262 0.373966231970543 0.468990438454861 GO:0008081 phosphoric diester hydrolase activity 1/101 87/18639 0.0114942528735632 2.12120177534995 0.377374274366435 0.471332767167874 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 1/101 89/18639 0.0112359550561798 2.07353431972411 0.384135346546672 0.475892372644865 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 1/101 89/18639 0.0112359550561798 2.07353431972411 0.384135346546672 0.475892372644865 GO:0019210 kinase inhibitor activity 1/101 90/18639 0.0111111111111111 2.05049504950495 0.387488571883534 0.476190775085789 GO:0140793 histone H2AXY142 phosphatase activity 1/101 90/18639 0.0111111111111111 2.05049504950495 0.387488571883534 0.476190775085789 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 1/101 91/18639 0.010989010989011 2.02796213687303 0.390823719559407 0.476462383207882 GO:0072341 modified amino acid binding 1/101 91/18639 0.010989010989011 2.02796213687303 0.390823719559407 0.476462383207882 GO:0052689 carboxylic ester hydrolase activity 1/101 92/18639 0.0108695652173913 2.00591907016789 0.394140886063855 0.478599647363252 GO:0051213 dioxygenase activity 1/101 93/18639 0.010752688172043 1.98435004790802 0.397440167376604 0.478805870934019 GO:0051219 phosphoprotein binding 1/101 93/18639 0.010752688172043 1.98435004790802 0.397440167376604 0.478805870934019 GO:0004725 protein tyrosine phosphatase activity 1/101 98/18639 0.0102040816326531 1.88310769852495 0.413671620001383 0.494466858282903 GO:0042626 ATPase-coupled transmembrane transporter activity 1/101 98/18639 0.0102040816326531 1.88310769852495 0.413671620001383 0.494466858282903 GO:0008238 exopeptidase activity 1/101 102/18639 0.00980392156862745 1.80926033779849 0.426344453257797 0.507631917108505 GO:0016791 phosphatase activity 2/101 273/18639 0.00732600732600733 1.35197475791535 0.436848283199017 0.518122382398834 GO:0019888 protein phosphatase regulator activity 1/101 107/18639 0.00934579439252336 1.72471546220043 0.441804718450267 0.521977775466339 GO:0004620 phospholipase activity 1/101 109/18639 0.00917431192660551 1.69306930693069 0.447872666444043 0.527111676661066 GO:1902936 phosphatidylinositol bisphosphate binding 1/101 111/18639 0.00900900900900901 1.66256355365266 0.45387529793211 0.532129659644543 GO:0035091 phosphatidylinositol binding 2/101 284/18639 0.00704225352112676 1.29960953841863 0.456956531537195 0.53369732309306 GO:0001221 transcription coregulator binding 1/101 115/18639 0.00869565217391304 1.60473525613431 0.4656873885384 0.535715567265978 GO:0017124 SH3 domain binding 1/101 115/18639 0.00869565217391304 1.60473525613431 0.4656873885384 0.535715567265978 GO:0035401 histone H3Y41 kinase activity 1/101 115/18639 0.00869565217391304 1.60473525613431 0.4656873885384 0.535715567265978 GO:0140801 histone H2AXY142 kinase activity 1/101 115/18639 0.00869565217391304 1.60473525613431 0.4656873885384 0.535715567265978 GO:0019208 phosphatase regulator activity 1/101 117/18639 0.00854700854700855 1.57730388423458 0.471498217944688 0.540368744161328 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/101 122/18639 0.00819672131147541 1.51266028242168 0.485752980009665 0.554628402548348 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 3/101 484/18639 0.00619834710743802 1.14387120530235 0.489702934165986 0.557059843326363 GO:0001216 DNA-binding transcription activator activity 3/101 491/18639 0.00610997963340122 1.12756346917787 0.499290435401285 0.565862493454789 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 1/101 128/18639 0.0078125 1.44175433168317 0.502356962611138 0.567237013132872 GO:0016298 lipase activity 1/101 130/18639 0.00769230769230769 1.41957349581112 0.507772788559592 0.569151916847015 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 1/101 130/18639 0.00769230769230769 1.41957349581112 0.507772788559592 0.569151916847015 GO:0005179 hormone activity 1/101 132/18639 0.00757575757575758 1.39806480648065 0.513130251600139 0.570974025416882 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 1/101 132/18639 0.00757575757575758 1.39806480648065 0.513130251600139 0.570974025416882 GO:0140789 histone phosphatase activity 1/101 136/18639 0.00735294117647059 1.35694525334886 0.523672573250283 0.580593505125314 GO:0070851 growth factor receptor binding 1/101 139/18639 0.00719424460431655 1.32765866514709 0.53143069565971 0.587067844302784 GO:0004713 protein tyrosine kinase activity 1/101 140/18639 0.00714285714285714 1.31817538896747 0.533988830780703 0.587771878485234 GO:0045296 cadherin binding 2/101 334/18639 0.00598802395209581 1.10505721230806 0.542903700985743 0.595442768823073 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 2/101 349/18639 0.00573065902578797 1.05756191665012 0.566815405411734 0.61895183489802 GO:0005506 iron ion binding 1/101 154/18639 0.00649350649350649 1.1983412626977 0.568383874530535 0.61895183489802 GO:0015399 primary active transmembrane transporter activity 1/101 166/18639 0.00602409638554217 1.11171418346654 0.595856296916574 0.64656747112224 GO:0004721 phosphoprotein phosphatase activity 1/101 175/18639 0.00571428571428571 1.05454031117397 0.615317685068624 0.66532583615194 GO:0005319 lipid transporter activity 1/101 178/18639 0.00561797752808989 1.03676715986205 0.621596311584639 0.669748138538379 GO:0031406 carboxylic acid binding 1/101 187/18639 0.0053475935828877 0.98686927516281 0.639829787783209 0.686975140567235 GO:0043177 organic acid binding 1/101 189/18639 0.00529100529100529 0.976426214049976 0.643762002567758 0.688780324425643 GO:0016758 hexosyltransferase activity 1/101 197/18639 0.0050761421319797 0.936774388098708 0.659070286689138 0.702702117515249 GO:0016829 lyase activity 1/101 200/18639 0.005 0.922722772277228 0.664641403245276 0.706181490948106 GO:0003714 transcription corepressor activity 1/101 204/18639 0.00490196078431373 0.904630168899243 0.671929574708037 0.71145484380851 GO:0051015 actin filament binding 1/101 209/18639 0.00478468899521531 0.882988298829883 0.680819604177126 0.718382065097243 GO:0000287 magnesium ion binding 1/101 230/18639 0.00434782608695652 0.802367628067155 0.715625221203247 0.752513119203414 GO:0042393 histone binding 1/101 247/18639 0.00404858299595142 0.747143945163747 0.741026475053233 0.776555141665374 GO:0003712 transcription coregulator activity 2/101 495/18639 0.00404040404040404 0.745634563456346 0.753079853350863 0.783231759802678 GO:0003713 transcription coactivator activity 1/101 256/18639 0.00390625 0.720877165841584 0.753550979736765 0.783231759802678 GO:0005543 phospholipid binding 2/101 497/18639 0.00402414486921529 0.742634021953503 0.755076369744412 0.783231759802678 GO:0016757 glycosyltransferase activity 1/101 267/18639 0.00374531835205993 0.691178106574702 0.768046779729271 0.791277146677618 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 1/101 268/18639 0.00373134328358209 0.688599083788976 0.769321941673934 0.791277146677618 GO:0008514 organic anion transmembrane transporter activity 1/101 269/18639 0.00371747211895911 0.68603923589385 0.770590162450752 0.791277146677618 GO:0001217 DNA-binding transcription repressor activity 1/101 278/18639 0.00359712230215827 0.663829332573545 0.781697903750893 0.799998523571148 GO:0031267 small GTPase binding 1/101 283/18639 0.00353356890459364 0.65210089913585 0.787637020236834 0.803389760641571 GO:0051020 GTPase binding 1/101 315/18639 0.00317460317460317 0.585855728429986 0.822034822119608 0.835689885609967 GO:0141003 histone H2AX kinase activity 1/101 354/18639 0.00282485875706215 0.521312300721598 0.856576060127494 0.866931095250716 GO:0140996 histone H3 kinase activity 1/101 357/18639 0.00280112044817927 0.516931525085282 0.858939757286406 0.866931095250716 GO:0035173 histone kinase activity 1/101 360/18639 0.00277777777777778 0.512623762376238 0.861264878941888 0.866931095250716 GO:0016887 ATP hydrolysis activity 1/101 417/18639 0.00239808153477218 0.442552888382363 0.898885306719928 0.901832471659993 GO:0022804 active transmembrane transporter activity 1/101 457/18639 0.00218818380743982 0.403817405810603 0.919061486100273 0.919061486100273