category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Cellular Processes	Transport and catabolism	hsa04145	Phagosome	18/97	155/9376	11.2250083139342	HLA-DRB1/HLA-DRA/ACTB/HLA-B/HLA-A/HLA-DPA1/HLA-DPB1/FCGR3A/ITGB2/HLA-C/CTSS/CYBB/HLA-DQA1/CYBA/OLR1/C1R/TUBA1B/ACTG1	13.123855073949
Organismal Systems	Immune system	hsa04612	Antigen processing and presentation	12/97	82/9376	14.1453356801609	CD74/HLA-DRB1/HLA-DRA/HLA-B/HLA-A/HLA-DPA1/HLA-DPB1/HLA-C/IFI30/CTSS/CTSB/HLA-DQA1	12.2235735726346
Human Diseases	Cardiovascular disease	hsa05416	Viral myocarditis	11/97	70/9376	15.1893961708395	HLA-DRB1/HLA-DRA/ACTB/HLA-B/HLA-A/HLA-DPA1/HLA-DPB1/ITGB2/HLA-C/HLA-DQA1/ACTG1	12.1829462555905
Human Diseases	Neurodegenerative disease	hsa05020	Prion disease	18/97	275/9376	6.3268228678538	MT-CO2/MT-CO3/MT-ND3/MT-ATP6/MT-CYB/C1QA/C1QB/MT-CO1/MT-ND1/CYBB/MT-ND2/CYBA/C1QC/CSNK2A1/CYC1/MT-ND4/TUBA1B/IL1B	9.1666566214055
Human Diseases	Infectious disease: bacterial	hsa05150	Staphylococcus aureus infection	12/97	99/9376	11.7163386441737	HLA-DRB1/HLA-DRA/HLA-DPA1/C1QA/HLA-DPB1/FCGR3A/C1QB/ITGB2/HLA-DQA1/C1QC/C1R/PTAFR	10.9592583797737
Human Diseases	Infectious disease: parasitic	hsa05140	Leishmaniasis	11/97	78/9376	13.6315093840867	HLA-DRB1/HLA-DRA/HLA-DPA1/NFKBIA/HLA-DPB1/FCGR3A/ITGB2/CYBB/HLA-DQA1/CYBA/IL1B	11.4532488634016
Human Diseases	Endocrine and metabolic disease	hsa04940	Type I diabetes mellitus	9/97	44/9376	19.7713214620431	HLA-DRB1/HLA-DRA/HLA-B/HLA-A/HLA-DPA1/HLA-DPB1/HLA-C/HLA-DQA1/IL1B	12.7601194018212
Human Diseases	Immune disease	hsa05332	Graft-versus-host disease	9/97	45/9376	19.3319587628866	HLA-DRB1/HLA-DRA/HLA-B/HLA-A/HLA-DPA1/HLA-DPB1/HLA-C/HLA-DQA1/IL1B	12.6029424118681
Human Diseases	Immune disease	hsa05330	Allograft rejection	8/97	39/9376	19.827650013217	HLA-DRB1/HLA-DRA/HLA-B/HLA-A/HLA-DPA1/HLA-DPB1/HLA-C/HLA-DQA1	12.0460776599549
Human Diseases	Immune disease	hsa05323	Rheumatoid arthritis	10/97	95/9376	10.1747151383614	HLA-DRB1/HLA-DRA/HLA-DPA1/HLA-DPB1/ITGB2/HLA-DQA1/CCL3/CXCL2/ACP5/IL1B	9.18920463990125
Human Diseases	Immune disease	hsa05320	Autoimmune thyroid disease	8/97	54/9376	14.3199694539901	HLA-DRB1/HLA-DRA/HLA-B/HLA-A/HLA-DPA1/HLA-DPB1/HLA-C/HLA-DQA1	10.0361346054574
Human Diseases	Cardiovascular disease	hsa05415	Diabetic cardiomyopathy	13/97	205/9376	6.12964546140307	MT-CO2/MT-CO3/MT-ND3/MT-ATP6/MT-CYB/CTSD/MT-CO1/MT-ND1/CYBB/MT-ND2/CYBA/CYC1/MT-ND4	7.59236103045371
Human Diseases	Infectious disease: viral	hsa05168	Herpes simplex virus 1 infection	12/97	180/9376	6.44398625429553	CD74/HLA-DRB1/HLA-DRA/HLA-B/HLA-A/HLA-DPA1/NFKBIA/HLA-DPB1/HLA-C/HLA-DQA1/BIRC3/IL1B	7.54005839252557
Human Diseases	Infectious disease: bacterial	hsa05152	Tuberculosis	12/97	181/9376	6.4083841202939	CD74/HLA-DRB1/HLA-DRA/HLA-DPA1/CTSD/HLA-DPB1/FCGR3A/ITGB2/FCER1G/CTSS/HLA-DQA1/IL1B	7.51193579957695
Human Diseases	Cancer: overview	hsa05208	Chemical carcinogenesis - reactive oxygen species	13/97	227/9376	5.53558290567237	MT-CO2/MT-CO3/MT-ND3/MT-ATP6/MT-CYB/NFKBIA/MT-CO1/MT-ND1/MT-ND2/SOD2/CYBA/CYC1/MT-ND4	7.07261703236354
Human Diseases	Immune disease	hsa05310	Asthma	6/97	32/9376	18.1237113402062	HLA-DRB1/HLA-DRA/HLA-DPA1/HLA-DPB1/FCER1G/HLA-DQA1	9.92035903781733
Human Diseases	Neurodegenerative disease	hsa05014	Amyotrophic lateral sclerosis	16/97	368/9376	4.2025997310623	PFN1/MT-CO2/MT-CO3/MT-ND3/MT-ATP6/ACTB/MT-CYB/MT-CO1/MT-ND1/MT-ND2/GPX1/CYC1/MT-ND4/TUBA1B/ACTG1/HDAC6	6.40815933084212
Metabolism	Energy metabolism	hsa00190	Oxidative phosphorylation	10/97	138/9376	7.00433288510384	MT-CO2/MT-CO3/MT-ND3/MT-ATP6/MT-CYB/MT-CO1/MT-ND1/MT-ND2/CYC1/MT-ND4	7.26501046289922
Human Diseases	Immune disease	hsa05322	Systemic lupus erythematosus	10/97	143/9376	6.75942614086944	HLA-DRB1/HLA-DRA/HLA-DPA1/C1QA/HLA-DPB1/FCGR3A/C1QB/HLA-DQA1/C1QC/C1R	7.09572428782169
Human Diseases	Neurodegenerative disease	hsa05016	Huntington disease	14/97	308/9376	4.39362699156514	MT-CO2/MT-CO3/MT-ND3/MT-ATP6/MT-CYB/MT-CO1/MT-ND1/MT-ND2/SOD2/GPX1/CYC1/MT-ND4/TUBA1B/CLTB	6.19162472567018
Organismal Systems	Environmental adaptation	hsa04714	Thermogenesis	12/97	235/9376	4.93581925860934	MT-CO2/MT-CO3/MT-ND3/MT-ATP6/ACTB/MT-CYB/MT-CO1/MT-ND1/MT-ND2/CYC1/MT-ND4/ACTG1	6.24731121327031
Environmental Information Processing	Signaling molecules and interaction	hsa04514	Cell adhesion molecule (CAM) interaction	10/97	160/9376	6.04123711340206	HLA-DRB1/HLA-DRA/HLA-B/HLA-A/HLA-DPA1/HLA-DPB1/ITGB2/HLA-C/HLA-DQA1/PTPRC	6.57577282522665
Human Diseases	Infectious disease: viral	hsa05169	Epstein-Barr virus infection	11/97	205/9376	5.18662308272567	HLA-DRB1/HLA-DRA/HLA-B/HLA-A/HLA-DPA1/NFKBIA/HLA-DPB1/VIM/HLA-C/HLA-DQA1/CXCL10	6.1965986112791
Human Diseases	Neurodegenerative disease	hsa05010	Alzheimer disease	15/97	388/9376	3.73684769901158	MT-CO2/MT-CO3/MT-ND3/MT-ATP6/MT-CYB/APOE/MT-CO1/MT-ND1/CYBB/MT-ND2/CSNK2A1/CYC1/MT-ND4/TUBA1B/IL1B	5.62931925190034
Human Diseases	Infectious disease: viral	hsa05164	Influenza A	10/97	173/9376	5.58727131875335	HLA-DRB1/HLA-DRA/ACTB/HLA-DPA1/NFKBIA/HLA-DPB1/HLA-DQA1/CXCL10/ACTG1/IL1B	6.22635224074331
Cellular Processes	Cell growth and death	hsa04210	Apoptosis	9/97	137/9376	6.34991346226202	ACTB/CTSD/NFKBIA/CTSS/CTSB/TUBA1B/BIRC3/ACTG1/BCL2A1	6.44934300269343
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	11/97	238/9376	4.46746946201161	RPL13/C1QA/NFKBIA/C1QB/CYBB/CXCL10/C1QC/C1R/RPL7/HBEGF/IL1B	5.53983034153467
Human Diseases	Infectious disease: parasitic	hsa05143	African trypanosomiasis	5/97	37/9376	13.0621342992477	HBA2/HBA1/HBB/IDO1/IL1B	7.51615541937267
Human Diseases	Immune disease	hsa05321	Inflammatory bowel disease	6/97	66/9376	8.78725398313027	HLA-DRB1/HLA-DRA/HLA-DPA1/HLA-DPB1/HLA-DQA1/IL1B	6.49086213381822
Human Diseases	Neurodegenerative disease	hsa05012	Parkinson disease	11/97	268/9376	3.96737959686106	MT-CO2/MT-CO3/MT-ND3/MT-ATP6/MT-CYB/MT-CO1/MT-ND1/MT-ND2/CYC1/MT-ND4/TUBA1B	5.03906441751404
Human Diseases	Infectious disease: viral	hsa05166	Human T-cell leukemia virus 1 infection	10/97	224/9376	4.31516936671576	HLA-DRB1/HLA-DRA/HLA-B/HLA-A/HLA-DPA1/NFKBIA/HLA-DPB1/ITGB2/HLA-C/HLA-DQA1	5.13443478612309
Organismal Systems	Development and regeneration	hsa04380	Osteoclast differentiation	8/97	142/9376	5.44562218672862	JUNB/NFKBIA/TYROBP/FCGR3A/CYBA/TREM2/ACP5/IL1B	5.45761261944188
Human Diseases	Neurodegenerative disease	hsa05022	Pathways of neurodegeneration - multiple diseases	15/97	480/9376	3.02061855670103	MT-CO2/MT-CO3/MT-ND3/MT-ATP6/MT-CYB/MT-CO1/MT-ND1/CYBB/MT-ND2/CSNK2A1/GPX1/CYC1/MT-ND4/TUBA1B/IL1B	4.64652723048448
Organismal Systems	Immune system	hsa04659	Th17 cell differentiation	7/97	109/9376	6.20750969450487	HLA-DRB1/HLA-DRA/HLA-DPA1/NFKBIA/HLA-DPB1/HLA-DQA1/IL1B	5.59106669021017
Organismal Systems	Immune system	hsa04621	NOD-like receptor signaling pathway	9/97	187/9376	4.65207563812779	NFKBIA/CYBB/CTSB/TXNIP/CYBA/GBP5/CXCL2/BIRC3/IL1B	5.15759645983097
Human Diseases	Infectious disease: bacterial	hsa05133	Pertussis	6/97	78/9376	7.43536875495638	C1QA/C1QB/ITGB2/C1QC/C1R/IL1B	5.835080958031
Human Diseases	Infectious disease: parasitic	hsa05145	Toxoplasmosis	7/97	112/9376	6.04123711340206	HLA-DRB1/HLA-DRA/HLA-DPA1/NFKBIA/HLA-DPB1/HLA-DQA1/BIRC3	5.48741468269114
Organismal Systems	Immune system	hsa04672	Intestinal immune network for IgA production	5/97	50/9376	9.6659793814433	HLA-DRB1/HLA-DRA/HLA-DPA1/HLA-DPB1/HLA-DQA1	6.28168082581679
Human Diseases	Infectious disease: parasitic	hsa05144	Malaria	5/97	50/9376	9.6659793814433	HBA2/HBA1/HBB/ITGB2/IL1B	6.28168082581679
Organismal Systems	Immune system	hsa04610	Complement and coagulation cascades	6/97	88/9376	6.5904404873477	C1QA/C1QB/ITGB2/C1QC/SERPINA1/C1R	5.38700252691577
Organismal Systems	Immune system	hsa04658	Th1 and Th2 cell differentiation	6/97	93/9376	6.23611572996342	HLA-DRB1/HLA-DRA/HLA-DPA1/NFKBIA/HLA-DPB1/HLA-DQA1	5.18832835872127
Organismal Systems	Immune system	hsa04650	Natural killer cell mediated cytotoxicity	7/97	133/9376	5.08735756918068	HLA-B/HLA-A/TYROBP/FCGR3A/ITGB2/FCER1G/HLA-C	4.8538113642379
Organismal Systems	Immune system	hsa04640	Hematopoietic cell lineage	6/97	100/9376	5.79958762886598	HLA-DRB1/HLA-DRA/HLA-DPA1/HLA-DPB1/HLA-DQA1/IL1B	4.9333789139385
Human Diseases	Infectious disease: parasitic	hsa05142	Chagas disease	6/97	103/9376	5.63066760084076	C1QA/NFKBIA/C1QB/C1QC/CCL3/IL1B	4.83140014456585
Environmental Information Processing	Signal transduction	hsa04064	NF-kappa B signaling pathway	6/97	105/9376	5.52341678939617	NFKBIA/CSNK2A1/CXCL2/BIRC3/BCL2A1/IL1B	4.76561421614071
Organismal Systems	Immune system	hsa04620	Toll-like receptor signaling pathway	6/97	109/9376	5.32072259528989	CXCL9/NFKBIA/CXCL10/SPP1/CCL3/IL1B	4.63896365006395
Environmental Information Processing	Signal transduction	hsa04668	TNF signaling pathway	6/97	119/9376	4.87360304946721	JUNB/NFKBIA/CXCL10/CXCL2/BIRC3/IL1B	4.34784828006827
Human Diseases	Cardiovascular disease	hsa05417	Lipid and atherosclerosis	8/97	216/9376	3.57999236349752	NFKBIA/CYBB/SOD2/CYBA/OLR1/CCL3/CXCL2/IL1B	3.92209832684211
Organismal Systems	Circulatory system	hsa04260	Cardiac muscle contraction	5/97	87/9376	5.55516056404787	MT-CO2/MT-CO3/MT-CYB/MT-CO1/CYC1	4.36415083908741
Human Diseases	Infectious disease: bacterial	hsa05134	Legionellosis	4/97	56/9376	6.90427098674521	NFKBIA/ITGB2/CXCL2/IL1B	4.53078294728594
Environmental Information Processing	Signaling molecules and interaction	hsa04061	Viral protein interaction with cytokine and cytokine receptor	5/97	100/9376	4.83298969072165	CXCL9/CXCL13/CXCL10/CCL3/CXCL2	3.93983649841553
Human Diseases	Endocrine and metabolic disease	hsa04936	Alcoholic liver disease	6/97	144/9376	4.02749140893471	C1QA/NFKBIA/C1QB/C1QC/CXCL2/IL1B	3.74314960789582
Organismal Systems	Immune system	hsa04613	Neutrophil extracellular trap formation	7/97	195/9376	3.46983875231298	ACTB/FCGR3A/ITGB2/CYBB/CYBA/ACTG1/HDAC6	3.56337747575283
Human Diseases	Infectious disease: bacterial	hsa05132	Salmonella infection	8/97	248/9376	3.11805786498171	PFN1/ACTB/NFKBIA/PTPRC/TUBA1B/BIRC3/ACTG1/IL1B	3.45618326875265
Human Diseases	Endocrine and metabolic disease	hsa04932	Non-alcoholic fatty liver disease	6/97	157/9376	3.6940048591503	MT-CO2/MT-CO3/MT-CYB/MT-CO1/CYC1/IL1B	3.48038438431408
Organismal Systems	Immune system	hsa04670	Leukocyte transendothelial migration	5/97	116/9376	4.1663704230359	ACTB/ITGB2/CYBB/CYBA/ACTG1	3.50837606428368
Cellular Processes	Cell growth and death	hsa04216	Ferroptosis	3/97	42/9376	6.90427098674521	FTH1/FTL/CYBB	3.9208294074897
Organismal Systems	Immune system	hsa04062	Chemokine signaling pathway	6/97	193/9376	3.00496768335025	CXCL9/NFKBIA/CXCL13/CXCL10/CCL3/CXCL2	2.87749552728948
Organismal Systems	Immune system	hsa04657	IL-17 signaling pathway	4/97	94/9376	4.11318271550779	NFKBIA/CXCL10/CXCL2/IL1B	3.10147777436971
Human Diseases	Infectious disease: parasitic	hsa05146	Amoebiasis	4/97	103/9376	3.7537784005605	HSPB1/ITGB2/CXCL2/IL1B	2.87315059283347
Organismal Systems	Digestive system	hsa04978	Mineral absorption	3/97	61/9376	4.75376035152949	FTH1/FTL/MT2A	3.00719055517309
Cellular Processes	Cell growth and death	hsa04217	Necroptosis	5/97	168/9376	2.87677957781051	FTH1/FTL/CYBB/BIRC3/IL1B	2.50960963204009
Human Diseases	Infectious disease: viral	hsa05163	Human cytomegalovirus infection	6/97	227/9376	2.55488441800263	HLA-B/HLA-A/NFKBIA/HLA-C/CCL3/IL1B	2.424628156255
Environmental Information Processing	Signaling molecules and interaction	hsa04060	Cytokine-cytokine receptor interaction	7/97	298/9376	2.27053206946655	CXCL9/CXCL13/CXCL10/IL1RN/CCL3/CXCL2/IL1B	2.27887021588924
Human Diseases	Infectious disease: bacterial	hsa05120	Epithelial cell signaling in Helicobacter pylori infection	3/97	71/9376	4.08421664004646	NFKBIA/CXCL2/HBEGF	2.66708452512808
Cellular Processes	Transport and catabolism	hsa04142	Lysosome biogenesis	6/97	250/9376	2.31983505154639	CTSD/LAPTM5/CTSS/CTSB/CLTB/ACP5	2.1625708667149
Human Diseases	Infectious disease: bacterial	hsa05100	Bacterial invasion of epithelial cells	3/97	78/9376	3.71768437747819	ACTB/CLTB/ACTG1	2.46418021480866
Human Diseases	Infectious disease: viral	hsa05167	Kaposi sarcoma-associated herpesvirus infection	5/97	196/9376	2.46581106669472	HLA-B/HLA-A/NFKBIA/HLA-C/CXCL2	2.12034050259521
Organismal Systems	Immune system	hsa04623	Cytosolic DNA-sensing pathway	3/97	83/9376	3.49372748726866	NFKBIA/CXCL10/IL1B	2.33308729089411
Human Diseases	Infectious disease: bacterial	hsa05135	Yersinia infection	4/97	138/9376	2.80173315404154	ACTB/NFKBIA/ACTG1/IL1B	2.18002740120192
Human Diseases	Infectious disease: bacterial	hsa05130	Pathogenic Escherichia coli infection	5/97	200/9376	2.41649484536082	ACTB/NFKBIA/TUBA1B/ACTG1/IL1B	2.07025676189682
Human Diseases	Cardiovascular disease	hsa05418	Fluid shear stress and atherosclerosis	4/97	142/9376	2.72281109336431	ACTB/CYBA/ACTG1/IL1B	2.11498754710383
Human Diseases	Cancer: overview	hsa05205	Proteoglycans in cancer	5/97	204/9376	2.369112593491	ACTB/LUM/DCN/ACTG1/HBEGF	2.02135756369211
Human Diseases	Cancer: overview	hsa05203	Viral carcinogenesis	5/97	205/9376	2.35755594669349	HLA-B/HLA-A/NFKBIA/HLA-C/HDAC6	2.00931135375526
Human Diseases	Cancer: specific types	hsa05219	Bladder cancer	2/97	41/9376	4.71511189338698	TYMP/HBEGF	2.43740436055636
Organismal Systems	Nervous system	hsa04723	Retrograde endocannabinoid signaling	4/97	149/9376	2.59489379367605	MT-ND3/MT-ND1/MT-ND2/MT-ND4	2.00639094855658
Cellular Processes	Cellular community - eukaryotes	hsa04520	Adherens junction	3/97	93/9376	3.11805786498171	ACTB/CSNK2A1/ACTG1	2.09872742563962
NA	NA	hsa04518	Integrin signaling	4/97	154/9376	2.51064399518008	ACTB/ITGB2/SPP1/ACTG1	1.93255048552103
Cellular Processes	Transport and catabolism	hsa04148	Efferocytosis	4/97	157/9376	2.4626699061002	C1QA/C1QB/C1QC/DUSP2	1.88962298390319
Environmental Information Processing	Signal transduction	hsa04390	Hippo signaling pathway	4/97	157/9376	2.4626699061002	ACTB/ITGB2/BIRC3/ACTG1	1.88962298390319
Genetic Information Processing	Translation	hsa03010	Ribosome	5/97	222/9376	2.17702238320795	MT-RNR2/RPL13/MT-RNR1/RPL7/MRPL23	1.81458231106911
Metabolism	Metabolism of cofactors and vitamins	hsa00860	Porphyrin metabolism	2/97	46/9376	4.2025997310623	FTH1/FTL	2.22618716637847
Cellular Processes	Cell motility	hsa04810	Regulation of actin cytoskeleton	5/97	232/9376	2.08318521151795	TMSB4X/PFN1/ACTB/ITGB2/ACTG1	1.70804584712659
Organismal Systems	Immune system	hsa04625	C-type lectin receptor signaling pathway	3/97	105/9376	2.76170839469809	NFKBIA/FCER1G/IL1B	1.8560355946303
Human Diseases	Infectious disease: bacterial	hsa05110	Vibrio cholerae infection	2/97	51/9376	3.79058014958561	ACTB/ACTG1	2.04303631546828
Organismal Systems	Digestive system	hsa04979	Cholesterol metabolism	2/97	52/9376	3.71768437747819	APOC1/APOE	2.00918753541039
Genetic Information Processing	Chromosome	hsa03082	ATP-dependent chromatin remodeling	3/97	117/9376	2.47845625165213	ACTB/INO80E/ACTG1	1.64528176679981
Human Diseases	Infectious disease: bacterial	hsa05131	Shigellosis	5/97	253/9376	1.91027260502832	PFN1/ACTB/NFKBIA/ACTG1/IL1B	1.50066520802241
Organismal Systems	Immune system	hsa04611	Platelet activation	3/97	126/9376	2.3014236622484	ACTB/FCER1G/ACTG1	1.50367515116132
Cellular Processes	Cellular community - eukaryotes	hsa04510	Focal adhesion	4/97	203/9376	1.90462647910213	ACTB/SPP1/BIRC3/ACTG1	1.33224020508492
Organismal Systems	Endocrine system	hsa04920	Adipocytokine signaling pathway	2/97	70/9376	2.76170839469809	NFKBIA/POMC	1.51259422404017
Human Diseases	Infectious disease: viral	hsa05162	Measles	3/97	136/9376	2.1322013341419	NFKBIA/CSNK2A1/IL1B	1.35980943081202
Organismal Systems	Immune system	hsa04622	RIG-I-like receptor signaling pathway	2/97	72/9376	2.68499427262314	NFKBIA/CXCL10	1.46740753345616
Organismal Systems	Endocrine system	hsa04915	Estrogen signaling pathway	3/97	139/9376	2.0861826003115	CTSD/POMC/HBEGF	1.31906345354604
Environmental Information Processing	Signal transduction	hsa04015	Rap1 signaling pathway	4/97	212/9376	1.82376969461194	PFN1/ACTB/ITGB2/ACTG1	1.24037247127748
Human Diseases	Infectious disease: viral	hsa05170	Human immunodeficiency virus 1 infection	4/97	214/9376	1.80672511802678	HLA-B/HLA-A/NFKBIA/HLA-C	1.22055749016301
Human Diseases	Drug resistance: antineoplastic	hsa01524	Platinum drug resistance	2/97	75/9376	2.57759450171821	BIRC3/TOP2A	1.40243296472139
Organismal Systems	Digestive system	hsa04971	Gastric acid secretion	2/97	76/9376	2.54367878459034	ACTB/ACTG1	1.38147546212015
NA	NA	hsa04517	IgSF CAM signaling	5/97	299/9376	1.61638451194704	ACTB/ITGB2/SLAMF7/TUBA1B/ACTG1	1.10748298340464
Organismal Systems	Endocrine system	hsa04921	Oxytocin signaling pathway	3/97	154/9376	1.88298299638506	ACTB/RGS2/ACTG1	1.12959057449359
Cellular Processes	Cell motility	hsa04820	Cytoskeleton in muscle cells	4/97	233/9376	1.65939560196452	ACTB/VIM/DCN/ACTG1	1.04207880969397
Cellular Processes	Cell growth and death	hsa04218	Cellular senescence	3/97	157/9376	1.84700242957515	HLA-B/HLA-A/HLA-C	1.09424228369774
Human Diseases	Cardiovascular disease	hsa05412	Arrhythmogenic right ventricular cardiomyopathy	2/97	86/9376	2.247902181731	ACTB/ACTG1	1.1886194446078
Human Diseases	Cancer: overview	hsa05235	PD-L1 expression and PD-1 checkpoint pathway in cancer	2/97	90/9376	2.14799541809851	NFKBIA/CSNK2A1	1.11884000811943
Organismal Systems	Digestive system	hsa04970	Salivary secretion	2/97	93/9376	2.07870524332114	LYZ/CST3	1.06886044794573
Human Diseases	Cancer: specific types	hsa05222	Small cell lung cancer	2/97	93/9376	2.07870524332114	NFKBIA/BIRC3	1.06886044794573
Cellular Processes	Cellular community - eukaryotes	hsa04530	Tight junction	3/97	170/9376	1.70576106731352	ACTB/TUBA1B/ACTG1	0.949440144194878
Cellular Processes	Transport and catabolism	hsa04144	Endocytosis	4/97	250/9376	1.54655670103093	HLA-B/HLA-A/HLA-C/CLTB	0.895541906749963
Human Diseases	Drug resistance: antineoplastic	hsa01523	Antifolate resistance	1/97	30/9376	3.22199312714777	IL1B	1.24626778289458
Organismal Systems	Immune system	hsa04666	Fc gamma R-mediated phagocytosis	2/97	98/9376	1.97264885335578	FCGR3A/PTPRC	0.98960721020429
Human Diseases	Cardiovascular disease	hsa05410	Hypertrophic cardiomyopathy	2/97	99/9376	1.95272310736228	ACTB/ACTG1	0.974319592227592
Metabolism	Carbohydrate metabolism	hsa00030	Pentose phosphate pathway	1/97	31/9376	3.11805786498171	FBP1	1.20767460158222
Human Diseases	Endocrine and metabolic disease	hsa04933	AGE-RAGE signaling pathway in diabetic complications	2/97	101/9376	1.91405532305808	CYBB/IL1B	0.944272034535704
Cellular Processes	Cell growth and death	hsa04215	Apoptosis - multiple species	1/97	32/9376	3.02061855670103	BIRC3	1.17061431150644
Human Diseases	Cardiovascular disease	hsa05414	Dilated cardiomyopathy	2/97	105/9376	1.84113892979872	ACTB/ACTG1	0.886176054126836
Metabolism	Carbohydrate metabolism	hsa00051	Fructose and mannose metabolism	1/97	35/9376	2.76170839469809	FBP1	1.06755996287487
Cellular Processes	Cell motility	hsa04814	Motor proteins	3/97	194/9376	1.49473907960463	ACTB/TUBA1B/ACTG1	0.711916986633704
Metabolism	Metabolism of cofactors and vitamins	hsa00760	Nicotinate and nicotinamide metabolism	1/97	38/9376	2.54367878459034	NNMT	0.974861046045463
Human Diseases	Immune disease	hsa05340	Primary immunodeficiency	1/97	38/9376	2.54367878459034	PTPRC	0.974861046045463
Metabolism	Amino acid metabolism	hsa00380	Tryptophan metabolism	1/97	42/9376	2.3014236622484	IDO1	0.864232041178615
Organismal Systems	Immune system	hsa04660	T cell receptor signaling pathway	2/97	122/9376	1.58458678384316	NFKBIA/PTPRC	0.66448484207525
Organismal Systems	Endocrine system	hsa04919	Thyroid hormone signaling pathway	2/97	122/9376	1.58458678384316	ACTB/ACTG1	0.66448484207525
Environmental Information Processing	Signal transduction	hsa04071	Sphingolipid signaling pathway	2/97	125/9376	1.54655670103093	CTSD/FCER1G	0.628950993263592
Organismal Systems	Endocrine system	hsa04910	Insulin signaling pathway	2/97	138/9376	1.40086657702077	FLOT2/FBP1	0.485033047302825
Organismal Systems	Excretory system	hsa04961	Endocrine and other factor-regulated calcium reabsorption	1/97	53/9376	1.82376969461194	CLTB	0.614874980028494
Genetic Information Processing	Replication and repair	hsa03460	Fanconi anemia pathway	1/97	54/9376	1.78999618174876	USP1	0.595234699690161
Human Diseases	Infectious disease: viral	hsa05165	Human papillomavirus infection	4/97	333/9376	1.16107860437757	HLA-B/HLA-A/HLA-C/SPP1	0.306002255366202
Metabolism	Nucleotide metabolism	hsa00240	Pyrimidine metabolism	1/97	59/9376	1.63830159007514	TYMP	0.502845771401216
Metabolism	Metabolism of other amino acids	hsa00480	Glutathione metabolism	1/97	59/9376	1.63830159007514	GPX1	0.502845771401216
Environmental Information Processing	Signal transduction	hsa04370	VEGF signaling pathway	1/97	60/9376	1.61099656357388	HSPB1	0.485423246945764
Organismal Systems	Aging	hsa04213	Longevity regulating pathway - multiple species	1/97	62/9376	1.55902893249085	SOD2	0.451526174796562
Human Diseases	Infectious disease: viral	hsa05160	Hepatitis C	2/97	156/9376	1.23922812582606	NFKBIA/CXCL10	0.308056228813121
Organismal Systems	Endocrine system	hsa04927	Cortisol synthesis and secretion	1/97	65/9376	1.48707375099128	POMC	0.402878562190691
Organismal Systems	Endocrine system	hsa04929	GnRH secretion	1/97	65/9376	1.48707375099128	SPP1	0.402878562190691
Metabolism	Carbohydrate metabolism	hsa00010	Glycolysis / Gluconeogenesis	1/97	67/9376	1.44268348976766	FBP1	0.371792075719064
Human Diseases	Cancer: specific types	hsa05221	Acute myeloid leukemia	1/97	68/9376	1.4214675560946	BCL2A1	0.356624631544169
Organismal Systems	Immune system	hsa04664	Fc epsilon RI signaling pathway	1/97	69/9376	1.40086657702077	FCER1G	0.34169643997816
Organismal Systems	Endocrine system	hsa04924	Renin secretion	1/97	69/9376	1.40086657702077	CTSB	0.34169643997816
Cellular Processes	Transport and catabolism	hsa04140	Autophagy - animal	2/97	169/9376	1.14390288537791	CTSD/CTSB	0.193007729007761
Human Diseases	Cancer: specific types	hsa05225	Hepatocellular carcinoma	2/97	170/9376	1.13717404487568	ACTB/ACTG1	0.184536312611172
Organismal Systems	Endocrine system	hsa04918	Thyroid hormone synthesis	1/97	75/9376	1.28879725085911	GPX1	0.256731868857684
Organismal Systems	Endocrine system	hsa03320	PPAR signaling pathway	1/97	76/9376	1.27183939229517	OLR1	0.243275643768786
Human Diseases	Cancer: specific types	hsa05220	Chronic myeloid leukemia	1/97	77/9376	1.25532199759004	NFKBIA	0.230004530351039
Organismal Systems	Nervous system	hsa04721	Synaptic vesicle cycle	1/97	79/9376	1.22354169385358	CLTB	0.20399596889612
Metabolism	Xenobiotics biodegradation and metabolism	hsa00983	Drug metabolism - other enzymes	1/97	82/9376	1.17877797334674	TYMP	0.166241909947459
Cellular Processes	Transport and catabolism	hsa04146	Peroxisome	1/97	83/9376	1.16457582908955	SOD2	0.153974232227658
Metabolism	Global and overview maps	hsa01232	Nucleotide metabolism	1/97	85/9376	1.13717404487568	TYMP	0.129888617926352
Environmental Information Processing	Signal transduction	hsa04012	ErbB signaling pathway	1/97	86/9376	1.1239510908655	HBEGF	0.118062680665174
Environmental Information Processing	Signal transduction	hsa04010	MAPK signaling pathway	3/97	300/9376	0.96659793814433	HSPB1/DUSP2/IL1B	-0.0601184226985955
Environmental Information Processing	Signaling molecules and interaction	hsa04512	ECM-receptor interaction	1/97	89/9376	1.08606509903857	SPP1	0.083407532116721
Cellular Processes	Cellular community - eukaryotes	hsa04540	Gap junction	1/97	89/9376	1.08606509903857	TUBA1B	0.083407532116721
NA	NA	hsa04519	Cadherin signaling	4/97	404/9376	0.95702766152904	ACTB/NFKBIA/VIM/ACTG1	-0.0902726010018529
Organismal Systems	Aging	hsa04211	Longevity regulating pathway	1/97	90/9376	1.07399770904926	SOD2	0.0721184040356367
Organismal Systems	Immune system	hsa04662	B cell receptor signaling pathway	1/97	91/9376	1.06219553642234	NFKBIA	0.0609550761214899
NA	NA	hsa04082	Neuroactive ligand signaling	2/97	199/9376	0.971455214215407	TAC3/POMC	-0.0416125067392772
Human Diseases	Cancer: overview	hsa05202	Transcriptional misregulation in cancer	2/97	201/9376	0.961788993178438	BIRC3/BCL2A1	-0.0559892166494458
Organismal Systems	Endocrine system	hsa04912	GnRH signaling pathway	1/97	93/9376	1.03935262166057	HBEGF	0.0389934702518482
Organismal Systems	Endocrine system	hsa04925	Aldosterone synthesis and secretion	1/97	98/9376	0.986324426677888	POMC	-0.0139140100937226
Human Diseases	Drug resistance: antineoplastic	hsa01522	Endocrine resistance	1/97	99/9376	0.976361553681141	HBEGF	-0.0241742865270153
Organismal Systems	Sensory system	hsa04750	Inflammatory mediator regulation of TRP channels	1/97	99/9376	0.976361553681141	IL1B	-0.0241742865270153
Organismal Systems	Endocrine system	hsa04916	Melanogenesis	1/97	101/9376	0.95702766152904	POMC	-0.0443929119530465
Cellular Processes	Transport and catabolism	hsa04137	Mitophagy - animal	1/97	105/9376	0.920569464899362	CSNK2A1	-0.0836834863766324
Human Diseases	Cancer: specific types	hsa05215	Prostate cancer	1/97	106/9376	0.911884847305972	NFKBIA	-0.093279150370263
Organismal Systems	Endocrine system	hsa04922	Glucagon signaling pathway	1/97	107/9376	0.903362559013392	FBP1	-0.102787851119535
Human Diseases	Endocrine and metabolic disease	hsa04931	Insulin resistance	1/97	109/9376	0.886787099214982	NFKBIA	-0.121551550667131
Environmental Information Processing	Signal transduction	hsa04024	cAMP signaling pathway	2/97	226/9376	0.85539640543746	NFKBIA/POMC	-0.224979879232767
Environmental Information Processing	Signal transduction	hsa04066	HIF-1 signaling pathway	1/97	110/9376	0.878725398313027	CYBB	-0.130810007187927
Environmental Information Processing	Signal transduction	hsa04350	TGF-beta signaling pathway	1/97	110/9376	0.878725398313027	DCN	-0.130810007187927
Organismal Systems	Endocrine system	hsa04928	Parathyroid hormone synthesis, secretion and action	1/97	115/9376	0.840519946212461	HBEGF	-0.175932984276866
Metabolism	Global and overview maps	hsa01200	Carbon metabolism	1/97	116/9376	0.833274084607181	FBP1	-0.184734295963741
Organismal Systems	Nervous system	hsa04722	Neurotrophin signaling pathway	1/97	120/9376	0.805498281786941	NFKBIA	-0.219241775366786
Environmental Information Processing	Signal transduction	hsa04152	AMPK signaling pathway	1/97	122/9376	0.792293391921582	FBP1	-0.236094787774062
Organismal Systems	Endocrine system	hsa04935	Growth hormone synthesis, secretion and action	1/97	122/9376	0.792293391921582	JUNB	-0.236094787774062
Environmental Information Processing	Signaling molecules and interaction	hsa04080	Neuroactive ligand-receptor interaction	3/97	370/9376	0.783728057954862	TAC3/POMC/PTAFR	-0.433966283438197
Organismal Systems	Endocrine system	hsa04926	Relaxin signaling pathway	1/97	130/9376	0.743536875495638	NFKBIA	-0.301051349669747
Environmental Information Processing	Signal transduction	hsa04068	FoxO signaling pathway	1/97	133/9376	0.726765367025812	SOD2	-0.324471090230388
Environmental Information Processing	Signal transduction	hsa04371	Apelin signaling pathway	1/97	140/9376	0.690427098674521	SPP1	-0.377316598908128
Genetic Information Processing	Folding, sorting and degradation	hsa04120	Ubiquitin mediated proteolysis	1/97	142/9376	0.680702773341077	BIRC3	-0.391981257149711
Environmental Information Processing	Signal transduction	hsa04072	Phospholipase D signaling pathway	1/97	149/9376	0.648723448419013	FCER1G	-0.441909107883466
Metabolism	Global and overview maps	hsa01240	Biosynthesis of cofactors	1/97	154/9376	0.627660998795019	IDO1	-0.476329247561284
Human Diseases	Endocrine and metabolic disease	hsa04934	Cushing syndrome	1/97	155/9376	0.623611572996342	POMC	-0.483096640691833
Human Diseases	Infectious disease: viral	hsa05161	Hepatitis B	1/97	163/9376	0.593004870027196	NFKBIA	-0.535924235577674
Environmental Information Processing	Signal transduction	hsa04022	cGMP-PKG signaling pathway	1/97	166/9376	0.582287914544777	RGS2	-0.555165139407934
Environmental Information Processing	Signal transduction	hsa04310	Wnt signaling pathway	1/97	178/9376	0.543032549519286	CSNK2A1	-0.629317028197426
Genetic Information Processing	Translation	hsa03008	Ribosome biogenesis in eukaryotes	1/97	183/9376	0.528195594614388	CSNK2A1	-0.65899151761176
Human Diseases	Substance dependence	hsa05034	Alcoholism	1/97	191/9376	0.506072218923733	HDAC6	-0.70511747034912
NA	NA	hsa04081	Hormone signaling	1/97	219/9376	0.441368921527091	POMC	-0.855246807202456
Environmental Information Processing	Signal transduction	hsa04020	Calcium signaling pathway	1/97	254/9376	0.380550369348161	PTAFR	-1.02329002500714
Human Diseases	Cancer: overview	hsa05206	MicroRNAs in cancer	1/97	323/9376	0.299256327598864	VIM	-1.31034333431532
Environmental Information Processing	Signal transduction	hsa04151	PI3K-Akt signaling pathway	1/97	362/9376	0.267016005012246	SPP1	-1.45415572722431
Organismal Systems	Sensory system	hsa04740	Olfactory transduction	1/97	449/9376	0.215277937225909	RGS2	-1.7422368057906