category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	31/202	238/9376	6.04576087860887	RPS18/RPL12/RPL10/CFD/RPS27/RPL29/RPL32/C1R/RPL36/C1S/RPL6/RPL5/RPS7/RPS6/RPS24/RPL10A/RPL3/RPLP0/RPL4/RPL34/FOS/RPS8/JUN/RPL7A/RPL7/RPL13A/RPL31/RPS3A/RPS13/RPS14/RPS15A	11.6996136876107
Genetic Information Processing	Translation	hsa03010	Ribosome	28/202	222/9376	5.85425028989385	MT-RNR2/RPS18/RPL12/RPL10/RPS27/MT-RNR1/RPL29/RPL32/RPL36/RPL6/RPL5/RPS7/RPS6/RPS24/RPL10A/RPL3/RPLP0/RPL4/RPL34/RPS8/RPL7A/RPL7/RPL13A/RPL31/RPS3A/RPS13/RPS14/RPS15A	10.8611335388232
Metabolism	Energy metabolism	hsa00190	Oxidative phosphorylation	14/202	138/9376	4.70885349404506	MT-CO1/MT-CYB/MT-CO3/MT-ND1/MT-ND3/MT-ND5/MT-ND4L/MT-ATP6/MT-ND4/MT-ATP8/MT-ND6/COX6C/MT-CO2/MT-ND2	6.51286682135616
Human Diseases	Cancer: overview	hsa05208	Chemical carcinogenesis - reactive oxygen species	18/202	227/9376	3.6805513150434	MT-CO1/MT-CYB/MT-CO3/MT-ND1/MT-ND3/MT-ND5/MT-ND4L/MT-ATP6/MT-ND4/MT-ATP8/MT-ND6/PTPN11/COX6C/MT-CO2/FOS/JUN/MT-ND2/NFE2L2	6.06641609704724
Organismal Systems	Environmental adaptation	hsa04714	Thermogenesis	18/202	235/9376	3.55525595112703	MT-CO1/MT-CYB/MT-CO3/MT-ND1/MT-ND3/MT-ND5/MT-ND4L/MT-ATP6/MT-ND4/ACTB/MT-ATP8/RPS6/MT-ND6/COX6C/MT-CO2/MT-ND2/SMARCE1/NPR1	5.88644973806995
Human Diseases	Cardiovascular disease	hsa05415	Diabetic cardiomyopathy	16/202	205/9376	3.62269983095871	MT-CO1/MT-CYB/MT-CO3/MT-ND1/MT-ND3/MT-ND5/MT-ND4L/MT-ATP6/MMP2/MT-ND4/MT-ATP8/MT-ND6/COX6C/MT-CO2/INSR/MT-ND2	5.63377018487991
Cellular Processes	Cell motility	hsa04820	Cytoskeleton in muscle cells	16/202	233/9376	3.1873539285259	VCAN/FN1/LMOD1/ACTB/TPM1/FBLN1/LAMA2/TPM4/SDC3/VCL/FBN1/THBS1/ZYX/NID1/TMEM43/MYL9	5.01689043106488
Human Diseases	Neurodegenerative disease	hsa05012	Parkinson disease	16/202	268/9376	2.77109501994976	MT-CO1/MT-CYB/MT-CO3/MT-ND1/MT-ND3/MT-ND5/MT-ND4L/MT-ATP6/MT-ND4/MT-ATP8/MT-ND6/COX6C/TUBB/MT-CO2/MT-ND2/NFE2L2	4.36495431854829
Cellular Processes	Cellular community - eukaryotes	hsa04510	Focal adhesion	13/202	203/9376	2.97244305711359	LAMB1/FN1/ACTB/FLT1/PAK3/PDGFRA/LAMA2/IGF1/VCL/JUN/THBS1/ZYX/MYL9	4.21578788575369
NA	NA	hsa04518	Integrin signaling	11/202	154/9376	3.31541725601132	LAMB1/FN1/ACTB/FLT1/PDGFRA/FERMT2/LAMA2/IGF1/VCL/FBN1/THBS1	4.29891662310181
Human Diseases	Neurodegenerative disease	hsa05010	Alzheimer disease	19/202	388/9376	2.27294069613147	MT-CO1/MT-CYB/MT-CO3/MT-ND1/MT-ND3/MT-ND5/MT-ND4L/MT-ATP6/MT-ND4/IRS2/MME/MT-ATP8/MT-ND6/COX6C/TUBB/MT-CO2/INSR/DKK1/MT-ND2	3.79992003190918
Human Diseases	Neurodegenerative disease	hsa05020	Prion disease	15/202	275/9376	2.53177317731773	MT-CO1/MT-CYB/MT-CO3/MT-ND1/MT-ND3/MT-ND5/MT-ND4L/MT-ATP6/MT-ND4/MT-ATP8/MT-ND6/COX6C/TUBB/MT-CO2/MT-ND2	3.82558807615843
Human Diseases	Neurodegenerative disease	hsa05016	Huntington disease	16/202	308/9376	2.41121254982641	MT-CO1/MT-CYB/MT-CO3/MT-ND1/MT-ND3/MT-ND5/MT-ND4L/MT-ATP6/MT-ND4/MT-ATP8/TGM2/MT-ND6/COX6C/TUBB/MT-CO2/MT-ND2	3.73674952087047
Human Diseases	Cancer: overview	hsa05202	Transcriptional misregulation in cancer	12/202	201/9376	2.77109501994976	HPGD/FOXO1/FLT1/PBX1/IGF1/MEIS1/ZEB1/MAF/MITF/ZBTB16/KLF3/MYC	3.7663338123611
Human Diseases	Neurodegenerative disease	hsa05014	Amyotrophic lateral sclerosis	17/202	368/9376	2.14421007318123	MT-CO1/MT-CYB/MT-CO3/MT-ND1/MT-ND3/MT-ND5/MT-ND4L/MT-ATP6/MT-ND4/ACTB/MT-ATP8/MT-ND6/COX6C/TUBB/MT-CO2/MT-ND2/HNRNPA1	3.32274828419732
Organismal Systems	Circulatory system	hsa04260	Cardiac muscle contraction	7/202	87/9376	3.73460794355298	MT-CO1/MT-CYB/MT-CO3/TPM1/COX6C/TPM4/MT-CO2	3.80235070439989
Organismal Systems	Immune system	hsa04610	Complement and coagulation cascades	7/202	88/9376	3.69216921692169	SERPINE2/SERPING1/CFD/C1R/C1S/CD55/VSIG4	3.76499619671206
Organismal Systems	Nervous system	hsa04723	Retrograde endocannabinoid signaling	9/202	149/9376	2.8036414379693	MT-ND1/MT-ND3/MT-ND5/MT-ND4L/MT-ND4/MT-ND6/GNG4/MT-ND2/GABRA2	3.29302504261999
Environmental Information Processing	Signal transduction	hsa04310	Wnt signaling pathway	10/202	178/9376	2.60763154967182	APCDD1/TCF7L2/NOTUM/SERPINF1/JUN/DKK1/MCC/SFRP4/MYC/PRICKLE2	3.2131557257664
Human Diseases	Infectious disease: bacterial	hsa05133	Pertussis	6/202	78/9376	3.57044935262757	SERPING1/C1R/C1S/FOS/CFL2/JUN	3.38254463813874
Human Diseases	Endocrine and metabolic disease	hsa04932	Non-alcoholic fatty liver disease	9/202	157/9376	2.6607807277543	MT-CO1/MT-CYB/MT-CO3/IRS2/COX6C/MT-CO2/FOS/INSR/JUN	3.1138821377426
Cellular Processes	Cell motility	hsa04810	Regulation of actin cytoskeleton	11/202	232/9376	2.20075110959372	TMSB4X/GSN/FN1/ACTB/PAK3/PDGFRA/FGF7/FGF10/CFL2/VCL/MYL9	2.74796271243028
Human Diseases	Cancer: specific types	hsa05224	Breast cancer	8/202	148/9376	2.50896440995451	TCF7L2/FGF7/PGR/IGF1/FOS/FGF10/JUN/MYC	2.74560474381547
Environmental Information Processing	Signal transduction	hsa04015	Rap1 signaling pathway	10/202	212/9376	2.18942648981879	ACTB/FLT1/PDGFRA/FGF7/IGF1/FGF10/INSR/THBS1/P2RY1/MAGI3	2.59923144100113
Human Diseases	Immune disease	hsa05323	Rheumatoid arthritis	6/202	95/9376	2.93152683689422	FLT1/CCL3L1/FOS/JUN/CCL3/HLA-DQA2	2.80767682969244
Human Diseases	Infectious disease: bacterial	hsa05150	Staphylococcus aureus infection	6/202	99/9376	2.81308130813081	CFD/C1R/C1S/KRT19/HLA-DQA2/KRT10	2.69099601487699
Human Diseases	Cancer: specific types	hsa05218	Melanoma	5/202	73/9376	3.17916723179167	PDGFRA/FGF7/IGF1/FGF10/MITF	2.77346336999447
Environmental Information Processing	Signal transduction	hsa04151	PI3K-Akt signaling pathway	14/202	362/9376	1.79508779607242	LAMB1/FN1/FLT1/PDGFRA/LAMA2/RPS6/FGF7/IGF1/FGF10/YWHAE/INSR/THBS1/GNG4/MYC	2.2892464578671
NA	NA	hsa04519	Cadherin signaling	15/202	404/9376	1.72336045485737	TCF7L2/ACTB/LHFPL3/PDGFRA/YWHAE/KRT19/VCL/KRT8/GABRA2/TEAD1/KRT10/CDH11/PRICKLE2/LIMA1/STK3	2.20537662891623
Environmental Information Processing	Signal transduction	hsa04350	TGF-beta signaling pathway	6/202	110/9376	2.53177317731773	RGMA/FBN1/THBS1/FST/MYC/ACVR1C	2.39787538785805
Human Diseases	Cancer: overview	hsa05205	Proteoglycans in cancer	9/202	204/9376	2.04775771694817	FN1/MMP2/ACTB/RPS6/IGF1/PTPN11/THBS1/TIMP3/MYC	2.24504930822497
Organismal Systems	Immune system	hsa04670	Leukocyte transendothelial migration	6/202	116/9376	2.40081939228406	MMP2/ACTB/PTPN11/VCL/CLDN10/MYL9	2.25261826698731
Organismal Systems	Aging	hsa04213	Longevity regulating pathway - multiple species	4/202	62/9376	2.99457042478441	FOXO1/IRS2/IGF1/INSR	2.33807833711555
Metabolism	Amino acid metabolism	hsa00350	Tyrosine metabolism	3/202	37/9376	3.76344661493176	AOX1/ADH1B/ADH5	2.49910042593645
Organismal Systems	Development and regeneration	hsa04360	Axon guidance	8/202	184/9376	2.01808006887645	PAK3/SEMA5A/RGMA/TRPC4/PTPN11/CFL2/MYL9/PLXNC1	2.06951126127805
Cellular Processes	Cellular community - eukaryotes	hsa04520	Adherens junction	5/202	93/9376	2.49547535398701	TCF7L2/ACTB/VCL/INSR/MYL9	2.15059441765206
Human Diseases	Neurodegenerative disease	hsa05022	Pathways of neurodegeneration - multiple diseases	16/202	480/9376	1.54719471947195	MT-CO1/MT-CYB/MT-CO3/MT-ND1/MT-ND3/MT-ND5/MT-ND4L/MT-ATP6/MT-ND4/MT-ATP8/MT-ND6/COX6C/TUBB/MT-CO2/DKK1/MT-ND2	1.82619472637822
Human Diseases	Cancer: specific types	hsa05219	Bladder cancer	3/202	41/9376	3.39628109152379	MMP2/THBS1/MYC	2.28167867328907
Human Diseases	Cardiovascular disease	hsa05410	Hypertrophic cardiomyopathy	5/202	99/9376	2.34423442344234	ACTB/TPM1/LAMA2/IGF1/TPM4	1.99512810612619
Human Diseases	Cardiovascular disease	hsa05416	Viral myocarditis	4/202	70/9376	2.65233380480905	ACTB/LAMA2/CD55/HLA-DQA2	2.05895682122082
Environmental Information Processing	Signal transduction	hsa04022	cGMP-PKG signaling pathway	7/202	166/9376	1.95729452463319	IRS2/EDNRB/INSR/EDNRA/ADRA2C/MYL9/NPR1	1.84651040347772
Organismal Systems	Circulatory system	hsa04270	Vascular smooth muscle contraction	6/202	134/9376	2.07832126496232	RAMP1/EDNRA/CALCRL/PPP1R14A/MYL9/NPR1	1.86551842126175
Environmental Information Processing	Signal transduction	hsa04014	Ras signaling pathway	9/202	238/9376	1.75522090024128	FLT1/PAK3/PDGFRA/FGF7/IGF1/PTPN11/FGF10/INSR/GNG4	1.75113188956126
Human Diseases	Cardiovascular disease	hsa05414	Dilated cardiomyopathy	5/202	105/9376	2.21027817067421	ACTB/TPM1/LAMA2/IGF1/TPM4	1.85054015865254
Human Diseases	Cancer: specific types	hsa05215	Prostate cancer	5/202	106/9376	2.18942648981879	TCF7L2/FOXO1/PDGFRA/IGF1/ZEB1	1.82739581956906
Organismal Systems	Endocrine system	hsa04915	Estrogen signaling pathway	6/202	139/9376	2.00356150722986	MMP2/PGR/FOS/KRT19/JUN/KRT10	1.76875580590011
Metabolism	Carbohydrate metabolism	hsa00620	Pyruvate metabolism	3/202	47/9376	2.96271329260586	ADH1B/LDHB/ADH5	2.00156731831114
Organismal Systems	Endocrine system	hsa04614	Renin-angiotensin system	2/202	23/9376	4.03616013775291	MME/ENPEP	2.16319205860434
Human Diseases	Infectious disease: bacterial	hsa05132	Salmonella infection	9/202	248/9376	1.68444586394123	TCF7L2/ACTB/PAK3/TUBB/DYNC2LI1/FOS/JUN/MYC/MYL9	1.62091067765567
Environmental Information Processing	Signal transduction	hsa04066	HIF-1 signaling pathway	5/202	110/9376	2.10981098109811	FLT1/RPS6/IGF1/INSR/LDHB	1.73732539266011
NA	NA	hsa04081	Hormone signaling	8/202	219/9376	1.69555585695556	IRS2/RAMP1/IGF1/TRH/INSR/GNG4/ADRA2C/NPR1	1.54546586554297
Environmental Information Processing	Signal transduction	hsa04010	MAPK signaling pathway	10/202	300/9376	1.54719471947195	FLT1/PDGFRA/FGF7/IGF1/FOS/FGF10/INSR/JUN/MYC/STK3	1.42934555848936
Organismal Systems	Endocrine system	hsa04921	Oxytocin signaling pathway	6/202	154/9376	1.80840941236981	ACTB/EEF2/FOS/JUN/MYL9/NPR1	1.50093234905543
Cellular Processes	Transport and catabolism	hsa04145	Phagosome	6/202	155/9376	1.79674225487065	ACTB/C1R/TUBB/THBS1/HLA-DQA2/EEA1	1.48414606002088
Human Diseases	Cancer: specific types	hsa05210	Colorectal cancer	4/202	87/9376	2.13406168203027	TCF7L2/FOS/JUN/MYC	1.57686232341524
Environmental Information Processing	Signal transduction	hsa04152	AMPK signaling pathway	5/202	122/9376	1.90228858951469	FOXO1/IRS2/IGF1/EEF2/INSR	1.48847857563739
Environmental Information Processing	Signal transduction	hsa04390	Hippo signaling pathway	6/202	157/9376	1.77385381850287	TCF7L2/ACTB/YWHAE/TEAD1/MYC/STK3	1.45093782845033
Environmental Information Processing	Signaling molecules and interaction	hsa04512	ECM-receptor interaction	4/202	89/9376	2.08610523973746	LAMB1/FN1/LAMA2/THBS1	1.52760525770649
Environmental Information Processing	Signal transduction	hsa04392	Hippo signaling pathway - multiple species	2/202	29/9376	3.20109252304541	TEAD1/STK3	1.7615019616551
Organismal Systems	Aging	hsa04211	Longevity regulating pathway	4/202	90/9376	2.06292629262926	FOXO1/IRS2/IGF1/INSR	1.5034604914152
Organismal Systems	Endocrine system	hsa04923	Regulation of lipolysis in adipocytes	3/202	59/9376	2.36012753817755	IRS2/INSR/NPR1	1.55506858099402
Organismal Systems	Immune system	hsa04658	Th1 and Th2 cell differentiation	4/202	93/9376	1.99638028318961	FOS/JUN/MAF/HLA-DQA2	1.43286204561868
Human Diseases	Cancer: specific types	hsa05222	Small cell lung cancer	4/202	93/9376	1.99638028318961	LAMB1/FN1/LAMA2/MYC	1.43286204561868
Human Diseases	Infectious disease: bacterial	hsa05130	Pathogenic Escherichia coli infection	7/202	200/9376	1.62455445544554	ACTB/PAK3/PTPN11/TUBB/FOS/CLDN10/JUN	1.32477023342373
Organismal Systems	Endocrine system	hsa04926	Relaxin signaling pathway	5/202	130/9376	1.78522467631379	MMP2/FOS/EDNRB/JUN/GNG4	1.33773665065928
Human Diseases	Immune disease	hsa05310	Asthma	2/202	32/9376	2.9009900990099	PRG2/HLA-DQA2	1.59834447523626
Human Diseases	Drug resistance: antineoplastic	hsa01522	Endocrine resistance	4/202	99/9376	1.87538753875388	MMP2/IGF1/FOS/JUN	1.29926019737538
Human Diseases	Immune disease	hsa05321	Inflammatory bowel disease	3/202	66/9376	2.10981098109811	JUN/MAF/HLA-DQA2	1.34254267679707
Human Diseases	Endocrine and metabolic disease	hsa04933	AGE-RAGE signaling pathway in diabetic complications	4/202	101/9376	1.83825115184786	FN1/MMP2/FOXO1/JUN	1.25678168068784
Metabolism	Carbohydrate metabolism	hsa00010	Glycolysis / Gluconeogenesis	3/202	67/9376	2.07832126496232	ADH1B/LDHB/ADH5	1.31436507616074
Organismal Systems	Endocrine system	hsa04910	Insulin signaling pathway	5/202	138/9376	1.68173339073038	FOXO1/IRS2/RPS6/RHOQ/INSR	1.19714590738821
Metabolism	Metabolism of cofactors and vitamins	hsa00830	Retinol metabolism	3/202	68/9376	2.04775771694817	AOX1/ADH1B/ADH5	1.28667568000763
Human Diseases	Cancer: specific types	hsa05221	Acute myeloid leukemia	3/202	68/9376	2.04775771694817	TCF7L2/ZBTB16/MYC	1.28667568000763
Human Diseases	Infectious disease: parasitic	hsa05142	Chagas disease	4/202	103/9376	1.8025569547246	CCL3L1/FOS/JUN/CCL3	1.21525187566172
Human Diseases	Infectious disease: parasitic	hsa05146	Amoebiasis	4/202	103/9376	1.8025569547246	LAMB1/FN1/LAMA2/VCL	1.21525187566172
Human Diseases	Cancer: specific types	hsa05216	Thyroid cancer	2/202	37/9376	2.50896440995451	TCF7L2/MYC	1.3646196670723
Human Diseases	Cancer: specific types	hsa05211	Renal cell carcinoma	3/202	70/9376	1.98925035360679	PAK3/PTPN11/JUN	1.23269508710995
Human Diseases	Cardiovascular disease	hsa05418	Fluid shear stress and atherosclerosis	5/202	142/9376	1.63436061916051	MMP2/ACTB/FOS/JUN/NFE2L2	1.13023149830181
Human Diseases	Cancer: overview	hsa05230	Central carbon metabolism in cancer	3/202	71/9376	1.96123274299261	PDGFRA/LDHB/MYC	1.2063726889276
Organismal Systems	Excretory system	hsa04960	Aldosterone-regulated sodium reabsorption	2/202	38/9376	2.44293903074518	IGF1/INSR	1.32249731671905
Metabolism	Xenobiotics biodegradation and metabolism	hsa00982	Drug metabolism - cytochrome P450	3/202	73/9376	1.907500339075	AOX1/ADH1B/ADH5	1.15499118744215
Organismal Systems	Immune system	hsa04620	Toll-like receptor signaling pathway	4/202	109/9376	1.70333363611591	CCL3L1/FOS/JUN/CCL3	1.0959405848783
Organismal Systems	Immune system	hsa04659	Th17 cell differentiation	4/202	109/9376	1.70333363611591	EBI3/FOS/JUN/HLA-DQA2	1.0959405848783
Human Diseases	Endocrine and metabolic disease	hsa04931	Insulin resistance	4/202	109/9376	1.70333363611591	FOXO1/IRS2/PTPN11/INSR	1.0959405848783
Metabolism	Amino acid metabolism	hsa00380	Tryptophan metabolism	2/202	42/9376	2.21027817067421	AOC1/AOX1	1.16642790815956
Organismal Systems	Endocrine system	hsa04928	Parathyroid hormone synthesis, secretion and action	4/202	115/9376	1.61446405510116	AKAP13/FOS/MMP14/NACA	0.983780966138515
Human Diseases	Infectious disease: bacterial	hsa05100	Bacterial invasion of epithelial cells	3/202	78/9376	1.78522467631379	FN1/ACTB/VCL	1.03330474723586
Human Diseases	Infectious disease: parasitic	hsa05140	Leishmaniasis	3/202	78/9376	1.78522467631379	FOS/JUN/HLA-DQA2	1.03330474723586
Metabolism	Lipid metabolism	hsa00071	Fatty acid degradation	2/202	43/9376	2.15887635275155	ADH1B/ADH5	1.13016707507862
Cellular Processes	Cell motility	hsa04814	Motor proteins	6/202	194/9376	1.43554149229356	ACTB/TPM1/TUBB/DYNC2LI1/TPM4/MYL9	0.909585881350766
Genetic Information Processing	Chromosome	hsa03082	ATP-dependent chromatin remodeling	4/202	117/9376	1.58686637894559	ACTB/MORF4L2/SMARCE1/MORF4L1	0.947833542548146
Human Diseases	Drug resistance: antineoplastic	hsa01521	EGFR tyrosine kinase inhibitor resistance	3/202	80/9376	1.74059405940594	PDGFRA/RPS6/IGF1	0.987095370541381
Cellular Processes	Transport and catabolism	hsa04148	Efferocytosis	5/202	157/9376	1.47821151541906	PBX1/PTPN11/BSG/THBS1/GULP1	0.89662305868624
Cellular Processes	Cell growth and death	hsa04218	Cellular senescence	5/202	157/9376	1.47821151541906	FOXO1/ZFP36L1/HIPK3/NBN/MYC	0.89662305868624
Environmental Information Processing	Signal transduction	hsa04668	TNF signaling pathway	4/202	119/9376	1.56019635577003	FOS/JUN/MMP14/JUNB	0.912558223629311
Organismal Systems	Nervous system	hsa04722	Neurotrophin signaling pathway	4/202	120/9376	1.54719471947195	PTPN11/YWHAE/JUN/KIDINS220	0.895164400995695
Environmental Information Processing	Signaling molecules and interaction	hsa04514	Cell adhesion molecule (CAM) interaction	5/202	160/9376	1.45049504950495	VCAN/SDC3/CLDN10/HLA-DQA2/NRXN2	0.852826597009532
Organismal Systems	Immune system	hsa04660	T cell receptor signaling pathway	4/202	122/9376	1.52183087161175	PAK3/PTPN11/FOS/JUN	0.860848825449581
Organismal Systems	Endocrine system	hsa04935	Growth hormone synthesis, secretion and action	4/202	122/9376	1.52183087161175	IRS2/IGF1/FOS/JUNB	0.860848825449581
Human Diseases	Endocrine and metabolic disease	hsa04930	Type II diabetes mellitus	2/202	47/9376	1.97514219507057	IRS2/INSR	0.994446186161024
Metabolism	Glycan biosynthesis and metabolism	hsa00604	Glycosphingolipid biosynthesis - ganglio series	1/202	15/9376	3.09438943894389	ST6GALNAC5	1.20454741845296
Environmental Information Processing	Signal transduction	hsa04012	ErbB signaling pathway	3/202	86/9376	1.61915726456367	PAK3/JUN/MYC	0.855902503162618
Human Diseases	Cardiovascular disease	hsa05412	Arrhythmogenic right ventricular cardiomyopathy	3/202	86/9376	1.61915726456367	TCF7L2/ACTB/LAMA2	0.855902503162618
Organismal Systems	Nervous system	hsa04727	GABAergic synapse	3/202	89/9376	1.56457892980309	PLCL1/GNG4/GABRA2	0.794079348853881
Human Diseases	Infectious disease: bacterial	hsa05131	Shigellosis	7/202	253/9376	1.2842327711032	ACTB/FOXO1/VCL/JUN/CBX3/CAST/MYL9	0.680060463923579
Cellular Processes	Cellular community - eukaryotes	hsa04530	Tight junction	5/202	170/9376	1.36517181129878	ACTB/CLDN10/JUN/YBX3/MYL9	0.712964943494027
Human Diseases	Cancer: specific types	hsa05225	Hepatocellular carcinoma	5/202	170/9376	1.36517181129878	TCF7L2/ACTB/SMARCE1/NFE2L2/MYC	0.712964943494027
Human Diseases	Cancer: overview	hsa05235	PD-L1 expression and PD-1 checkpoint pathway in cancer	3/202	90/9376	1.54719471947195	PTPN11/FOS/JUN	0.77398183443378
Organismal Systems	Endocrine system	hsa04913	Ovarian steroidogenesis	2/202	52/9376	1.78522467631379	IGF1/INSR	0.842512656318802
Environmental Information Processing	Signal transduction	hsa04068	FoxO signaling pathway	4/202	133/9376	1.39596516042582	FOXO1/IRS2/IGF1/INSR	0.682430257948206
Organismal Systems	Endocrine system	hsa04912	GnRH signaling pathway	3/202	93/9376	1.49728521239221	MMP2/JUN/MMP14	0.715129673585306
Metabolism	Amino acid metabolism	hsa00270	Cysteine and methionine metabolism	2/202	54/9376	1.71910524385772	AHCY/LDHB	0.786351539480817
Human Diseases	Cancer: overview	hsa05207	Chemical carcinogenesis - receptor activation	6/202	217/9376	1.28338732490761	FGF7/PGR/FOS/FGF10/JUN/MYC	0.626712293805682
Cellular Processes	Cell growth and death	hsa04210	Apoptosis	4/202	137/9376	1.35520705355207	ACTB/PTPN13/FOS/JUN	0.621457360697833
Human Diseases	Infectious disease: bacterial	hsa05135	Yersinia infection	4/202	138/9376	1.3453867125843	FN1/ACTB/FOS/JUN	0.606510250280662
Metabolism	Glycan biosynthesis and metabolism	hsa00541	Biosynthesis of various nucleotide sugars	1/202	20/9376	2.32079207920792	UAP1	0.877377114509749
Human Diseases	Cancer: overview	hsa05231	Choline metabolism in cancer	3/202	99/9376	1.40654065406541	PDGFRA/FOS/JUN	0.603392288624577
Human Diseases	Cancer: specific types	hsa05213	Endometrial cancer	2/202	59/9376	1.57341835878503	TCF7L2/MYC	0.655603866903955
Human Diseases	Infectious disease: viral	hsa05163	Human cytomegalovirus infection	6/202	227/9376	1.2268504383478	AKAP13/PDGFRA/CCL3L1/CCL3/GNG4/MYC	0.513390339924544
Environmental Information Processing	Signaling molecules and interaction	hsa04061	Viral protein interaction with cytokine and cytokine receptor	3/202	100/9376	1.39247524752475	CXCL14/CCL3L1/CCL3	0.585482417062333
Organismal Systems	Immune system	hsa04640	Hematopoietic cell lineage	3/202	100/9376	1.39247524752475	MME/CD55/HLA-DQA2	0.585482417062333
Organismal Systems	Development and regeneration	hsa04380	Osteoclast differentiation	4/202	142/9376	1.30748849532841	FOS/JUN/JUNB/MITF	0.547847978403054
Metabolism	Glycan biosynthesis and metabolism	hsa00532	Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate	1/202	21/9376	2.21027817067421	DSEL	0.823862824836111
Organismal Systems	Endocrine system	hsa04916	Melanogenesis	3/202	101/9376	1.37868836388589	TCF7L2/EDNRB/MITF	0.567763727341494
Cellular Processes	Cellular community - eukaryotes	hsa04550	Signaling pathways regulating pluripotency of stem cells	4/202	144/9376	1.28932893289329	IGF1/MEIS1/MYC/ACVR1C	0.519167106372119
Human Diseases	Endocrine and metabolic disease	hsa04936	Alcoholic liver disease	4/202	144/9376	1.28932893289329	TCF7L2/FOXO1/ADH1B/ADH5	0.519167106372119
Metabolism	Amino acid metabolism	hsa00340	Histidine metabolism	1/202	22/9376	2.10981098109811	AOC1	0.773292201285204
Organismal Systems	Digestive system	hsa04974	Protein digestion and absorption	3/202	103/9376	1.35191771604345	MME/COL15A1/CPB1	0.532882634662542
Metabolism	Metabolism of terpenoids and polyketides	hsa00900	Terpenoid backbone biosynthesis	1/202	23/9376	2.01808006887645	PCYOX1	0.725357892896534
Metabolism	Lipid metabolism	hsa00590	Arachidonic acid metabolism	2/202	63/9376	1.47351878044947	HPGD/PTGDS	0.559557391196186
Environmental Information Processing	Signaling molecules and interaction	hsa04080	Neuroactive ligand-receptor interaction	9/202	370/9376	1.12903398447953	P2RY14/S1PR3/EDNRB/TRH/EDNRA/CALCRL/ADRA2C/GABRA2/P2RY1	0.375769004239863
Human Diseases	Cancer: specific types	hsa05226	Gastric cancer	4/202	150/9376	1.23775577557756	TCF7L2/FGF7/FGF10/MYC	0.435563957443512
Human Diseases	Infectious disease: viral	hsa05167	Kaposi sarcoma-associated herpesvirus infection	5/202	196/9376	1.18407759143261	TCF7L2/FOS/JUN/GNG4/MYC	0.386446673486211
NA	NA	hsa04082	Neuroactive ligand signaling	5/202	199/9376	1.16622717548137	P2RY14/GNG4/ADRA2C/GABRA2/P2RY1	0.351690107798412
Human Diseases	Infectious disease: parasitic	hsa05145	Toxoplasmosis	3/202	112/9376	1.24328147100424	LAMB1/LAMA2/HLA-DQA2	0.384326849907821
Organismal Systems	Endocrine system	hsa04924	Renin secretion	2/202	69/9376	1.3453867125843	EDNRA/NPR1	0.42727478979752
Human Diseases	Substance dependence	hsa05031	Amphetamine addiction	2/202	69/9376	1.3453867125843	FOS/JUN	0.42727478979752
Organismal Systems	Endocrine system	hsa04920	Adipocytokine signaling pathway	2/202	70/9376	1.32616690240453	IRS2/PTPN11	0.406433352999076
Human Diseases	Infectious disease: bacterial	hsa05120	Epithelial cell signaling in Helicobacter pylori infection	2/202	71/9376	1.30748849532841	PTPN11/JUN	0.385906249685967
NA	NA	hsa04517	IgSF CAM signaling	7/202	299/9376	1.08665849862578	ACTB/FOXO1/PAK3/PTPN11/TUBB/VCL/MYL9	0.225973515477761
Environmental Information Processing	Signal transduction	hsa04020	Calcium signaling pathway	6/202	254/9376	1.0964372027754	FLT1/PDGFRA/FGF7/EDNRB/FGF10/EDNRA	0.231205618850516
Cellular Processes	Cell growth and death	hsa04115	p53 signaling pathway	2/202	75/9376	1.23775577557756	IGF1/THBS1	0.306745951962842
Human Diseases	Cancer: specific types	hsa05214	Glioma	2/202	76/9376	1.22146951537259	PDGFRA/IGF1	0.287647916185629
Human Diseases	Infectious disease: viral	hsa05170	Human immunodeficiency virus 1 infection	5/202	214/9376	1.0844822800037	PAK3/FOS/CFL2/JUN/GNG4	0.185506582223551
Organismal Systems	Endocrine system	hsa04919	Thyroid hormone signaling pathway	3/202	122/9376	1.14137315370881	ACTB/FOXO1/MYC	0.233219075261768
Metabolism	Carbohydrate metabolism	hsa00030	Pentose phosphate pathway	1/202	31/9376	1.49728521239221	PRPS2	0.41150838983464
Environmental Information Processing	Signal transduction	hsa04630	JAK-STAT signaling pathway	4/202	168/9376	1.10513908533711	PDGFRA/PTPN11/AOX1/MYC	0.20404132501251
Human Diseases	Cancer: specific types	hsa05220	Chronic myeloid leukemia	2/202	77/9376	1.20560627491321	PTPN11/MYC	0.268810085216086
Human Diseases	Cardiovascular disease	hsa05417	Lipid and atherosclerosis	5/202	216/9376	1.07444077741107	CCL3L1/FOS/JUN/CCL3/NFE2L2	0.164237374483138
Metabolism	Carbohydrate metabolism	hsa00640	Propanoate metabolism	1/202	32/9376	1.45049504950495	LDHB	0.378774341787759
Genetic Information Processing	Folding, sorting and degradation	hsa03018	RNA degradation	2/202	78/9376	1.19014978420919	PABPC1/TOB2	0.250224783601572
Metabolism	Xenobiotics biodegradation and metabolism	hsa00980	Metabolism of xenobiotics by cytochrome P450	2/202	79/9376	1.1750845970673	ADH1B/ADH5	0.231884663618899
Organismal Systems	Environmental adaptation	hsa04710	Circadian rhythm	1/202	34/9376	1.36517181129878	RORB	0.316518229485443
Genetic Information Processing	Chromosome	hsa03083	Polycomb repressive complex	2/202	83/9376	1.11845401407611	RYBP/CBX3	0.160839537267421
Environmental Information Processing	Signal transduction	hsa04024	cAMP signaling pathway	5/202	226/9376	1.026899150092	FOS/JUN/EDNRA/MYL9/NPR1	0.0607385172599947
Metabolism	Glycan biosynthesis and metabolism	hsa00512	Mucin type O-glycan biosynthesis	1/202	36/9376	1.28932893289329	GALNT13	0.258078385137452
Human Diseases	Cancer: overview	hsa05206	MicroRNAs in cancer	7/202	323/9376	1.00591607148331	TPM1/IRS2/PDGFRA/ZEB1/THBS1/TIMP3/MYC	0.0160553718653451
Metabolism	Global and overview maps	hsa01250	Biosynthesis of nucleotide sugars	1/202	37/9376	1.25448220497725	UAP1	0.23013890820815
Organismal Systems	Sensory system	hsa04742	Taste transduction	2/202	86/9376	1.07943817637578	GABRA2/P2RY1	0.109812704942768
Metabolism	Carbohydrate metabolism	hsa00520	Amino sugar and nucleotide sugar metabolism	1/202	38/9376	1.22146951537259	UAP1	0.202983517372913
Metabolism	Metabolism of cofactors and vitamins	hsa00760	Nicotinate and nicotinamide metabolism	1/202	38/9376	1.22146951537259	AOX1	0.202983517372913
Metabolism	Metabolism of cofactors and vitamins	hsa00670	One carbon pool by folate	1/202	39/9376	1.19014978420919	AHCY	0.176565730691064
Human Diseases	Immune disease	hsa05330	Allograft rejection	1/202	39/9376	1.19014978420919	HLA-DQA2	0.176565730691064
Cellular Processes	Cell growth and death	hsa04114	Oocyte meiosis	3/202	138/9376	1.00904003443823	PGR/IGF1/YWHAE	0.0158745931731126
Cellular Processes	Cellular community - eukaryotes	hsa04540	Gap junction	2/202	89/9376	1.04305261986873	PDGFRA/TUBB	0.0605534400012714
Organismal Systems	Immune system	hsa04662	B cell receptor signaling pathway	2/202	91/9376	1.02012838646502	FOS/JUN	0.0286299546071337
Human Diseases	Substance dependence	hsa05032	Morphine addiction	2/202	91/9376	1.02012838646502	GNG4/GABRA2	0.0286299546071337
Genetic Information Processing	Replication and repair	hsa03440	Homologous recombination	1/202	41/9376	1.1320936971746	NBN	0.125776300946198
Human Diseases	Substance dependence	hsa05033	Nicotine addiction	1/202	41/9376	1.1320936971746	GABRA2	0.125776300946198
Human Diseases	Immune disease	hsa05322	Systemic lupus erythematosus	3/202	143/9376	0.973758914352974	C1R/C1S/HLA-DQA2	-0.0469202540238368
Cellular Processes	Cell growth and death	hsa04216	Ferroptosis	1/202	42/9376	1.10513908533711	PCBP2	0.101329732574827
Organismal Systems	Immune system	hsa04062	Chemokine signaling pathway	4/202	193/9376	0.961986354075822	CXCL14/CCL3L1/CCL3/GNG4	-0.0791786043888757
Organismal Systems	Immune system	hsa04657	IL-17 signaling pathway	2/202	94/9376	0.987571097535285	FOS/JUN	-0.0179704056111416
Genetic Information Processing	Replication and repair	hsa03410	Base excision repair	1/202	44/9376	1.05490549054905	HMGB1	0.0541672396091611
Human Diseases	Endocrine and metabolic disease	hsa04940	Type I diabetes mellitus	1/202	44/9376	1.05490549054905	HLA-DQA2	0.0541672396091611
Organismal Systems	Excretory system	hsa04962	Vasopressin-regulated water reabsorption	1/202	44/9376	1.05490549054905	DYNC2LI1	0.0541672396091611
Organismal Systems	Environmental adaptation	hsa04713	Circadian entrainment	2/202	97/9376	0.95702766152904	FOS/GNG4	-0.063125702259482
Human Diseases	Immune disease	hsa05332	Graft-versus-host disease	1/202	45/9376	1.03146314631463	HLA-DQA2	0.0313925263244739
Environmental Information Processing	Signal transduction	hsa04072	Phospholipase D signaling pathway	3/202	149/9376	0.934547145989767	PDGFRA/PTPN11/INSR	-0.119501516670253
Organismal Systems	Immune system	hsa04666	Fc gamma R-mediated phagocytosis	2/202	98/9376	0.94726207314609	GSN/CFL2	-0.0778737094246179
Metabolism	Amino acid metabolism	hsa00280	Valine, leucine and isoleucine degradation	1/202	48/9376	0.966996699669967	AOX1	-0.0340146241489103
NA	NA	hsa03272	Virion - Hepatitis viruses	1/202	48/9376	0.966996699669967	CLDN10	-0.0340146241489103
Metabolism	Glycan biosynthesis and metabolism	hsa00514	Other types of O-glycan biosynthesis	1/202	49/9376	0.94726207314609	GALNT13	-0.0549201936859588
Human Diseases	Substance dependence	hsa05030	Cocaine addiction	1/202	49/9376	0.94726207314609	JUN	-0.0549201936859588
Human Diseases	Infectious disease: viral	hsa05160	Hepatitis C	3/202	156/9376	0.892612338156893	YWHAE/CLDN10/MYC	-0.200693441461169
Metabolism	Amino acid metabolism	hsa00330	Arginine and proline metabolism	1/202	50/9376	0.928316831683168	AOC1	-0.0754113028619244
Organismal Systems	Immune system	hsa04672	Intestinal immune network for IgA production	1/202	50/9376	0.928316831683168	HLA-DQA2	-0.0754113028619244
Human Diseases	Infectious disease: parasitic	hsa05144	Malaria	1/202	50/9376	0.928316831683168	THBS1	-0.0754113028619244
Cellular Processes	Transport and catabolism	hsa04137	Mitophagy - animal	2/202	105/9376	0.884111268269684	JUN/MITF	-0.177196248927462
Organismal Systems	Immune system	hsa04625	C-type lectin receptor signaling pathway	2/202	105/9376	0.884111268269684	PTPN11/JUN	-0.177196248927462
Environmental Information Processing	Signal transduction	hsa04150	mTOR signaling pathway	3/202	158/9376	0.881313447800476	RPS6/IGF1/INSR	-0.223251127307725
Metabolism	Lipid metabolism	hsa00565	Ether lipid metabolism	1/202	51/9376	0.910114540865851	PLA2G7	-0.0955063095747983
Human Diseases	Infectious disease: bacterial	hsa05110	Vibrio cholerae infection	1/202	51/9376	0.910114540865851	ACTB	-0.0955063095747983
Organismal Systems	Endocrine system	hsa04922	Glucagon signaling pathway	2/202	107/9376	0.867585824002961	FOXO1/LDHB	-0.204405174193998
Organismal Systems	Digestive system	hsa04979	Cholesterol metabolism	1/202	52/9376	0.892612338156893	APOC1	-0.115222390437392
Human Diseases	Infectious disease: viral	hsa05161	Hepatitis B	3/202	163/9376	0.854279292959971	FOS/JUN/MYC	-0.278481590977742
Organismal Systems	Endocrine system	hsa04914	Progesterone-mediated oocyte maturation	2/202	110/9376	0.843924392439244	PGR/IGF1	-0.244324592933709
NA	NA	hsa04382	Cornified envelope formation	4/202	217/9376	0.855591549938404	KRT19/CLDN10/KRT8/KRT10	-0.319359911430524
Genetic Information Processing	Replication and repair	hsa03460	Fanconi anemia pathway	1/202	54/9376	0.85955262192886	REV3L	-0.153581152280037
Human Diseases	Immune disease	hsa05320	Autoimmune thyroid disease	1/202	54/9376	0.85955262192886	HLA-DQA2	-0.153581152280037
Organismal Systems	Nervous system	hsa04725	Cholinergic synapse	2/202	115/9376	0.807232027550581	FOS/GNG4	-0.308629057472907
Human Diseases	Infectious disease: viral	hsa05166	Human T-cell leukemia virus 1 infection	4/202	224/9376	0.828854314002829	FOS/JUN/HLA-DQA2/MYC	-0.384692673297903
Metabolism	Global and overview maps	hsa01200	Carbon metabolism	2/202	116/9376	0.800273130761352	PRPS2/ADH5	-0.32117516114735
Genetic Information Processing	Folding, sorting and degradation	hsa04141	Protein processing in endoplasmic reticulum	3/202	174/9376	0.800273130761352	BAG2/NFE2L2/DNAJA1	-0.394595346347324
Human Diseases	Infectious disease: viral	hsa05165	Human papillomavirus infection	6/202	333/9376	0.836321469984836	LAMB1/FN1/TCF7L2/FOXO1/LAMA2/THBS1	-0.451273178975481
Organismal Systems	Nervous system	hsa04730	Long-term depression	1/202	60/9376	0.773597359735974	IGF1	-0.261050378652864
Human Diseases	Cancer: specific types	hsa05217	Basal cell carcinoma	1/202	63/9376	0.736759390224737	TCF7L2	-0.311071566629144
Human Diseases	Infectious disease: viral	hsa05168	Herpes simplex virus 1 infection	3/202	180/9376	0.773597359735974	PILRA/PTPN11/HLA-DQA2	-0.45509306079138
Environmental Information Processing	Signal transduction	hsa04071	Sphingolipid signaling pathway	2/202	125/9376	0.742653465346535	S1PR3/SPTSSA	-0.429794591046641
Organismal Systems	Endocrine system	hsa04927	Cortisol synthesis and secretion	1/202	65/9376	0.714089870525514	PBX1	-0.343217965192796
Organismal Systems	Endocrine system	hsa04929	GnRH secretion	1/202	65/9376	0.714089870525514	TRPC4	-0.343217965192796
Organismal Systems	Immune system	hsa04611	Platelet activation	2/202	126/9376	0.736759390224737	ACTB/P2RY1	-0.441417197698227
Metabolism	Nucleotide metabolism	hsa00230	Purine metabolism	2/202	128/9376	0.725247524752475	PRPS2/NPR1	-0.464413293897857
Organismal Systems	Immune system	hsa04621	NOD-like receptor signaling pathway	3/202	187/9376	0.744639169799333	TXNIP/YWHAE/JUN	-0.523386979266643
Environmental Information Processing	Signaling molecules and interaction	hsa04060	Cytokine-cytokine receptor interaction	5/202	298/9376	0.778789288324806	CXCL14/EBI3/CCL3L1/CCL3/ACVR1C	-0.575839100380594
Organismal Systems	Nervous system	hsa04728	Dopaminergic synapse	2/202	133/9376	0.697982580212908	FOS/GNG4	-0.520515051042653
Organismal Systems	Endocrine system	hsa04917	Prolactin signaling pathway	1/202	71/9376	0.653744247664203	FOS	-0.434560189555671
Human Diseases	Infectious disease: viral	hsa05162	Measles	2/202	136/9376	0.682585905649388	FOS/JUN	-0.55327574382393
Metabolism	Global and overview maps	hsa01230	Biosynthesis of amino acids	1/202	75/9376	0.618877887788779	PRPS2	-0.491713250037049
Human Diseases	Drug resistance: antineoplastic	hsa01524	Platinum drug resistance	1/202	75/9376	0.618877887788779	REV3L	-0.491713250037049
Environmental Information Processing	Signal transduction	hsa04371	Apelin signaling pathway	2/202	140/9376	0.663083451202263	RPS6/GNG4	-0.595972683293961
Organismal Systems	Endocrine system	hsa03320	PPAR signaling pathway	1/202	76/9376	0.610734757686295	FABP5	-0.505583513860388
Organismal Systems	Digestive system	hsa04971	Gastric acid secretion	1/202	76/9376	0.610734757686295	ACTB	-0.505583513860388
Metabolism	Carbohydrate metabolism	hsa00562	Inositol phosphate metabolism	1/202	78/9376	0.595074892104595	INPP4B	-0.53285518003272
Human Diseases	Infectious disease: viral	hsa05169	Epstein-Barr virus infection	3/202	205/9376	0.679256218304757	JUN/HLA-DQA2/MYC	-0.688983441021445
Human Diseases	Cancer: overview	hsa05203	Viral carcinogenesis	3/202	205/9376	0.679256218304757	GSN/YWHAE/JUN	-0.688983441021445
Organismal Systems	Immune system	hsa04612	Antigen processing and presentation	1/202	82/9376	0.566046848587298	HLA-DQA2	-0.585639543930604
Organismal Systems	Circulatory system	hsa04261	Adrenergic signaling in cardiomyocytes	2/202	154/9376	0.602803137456603	TPM1/TPM4	-0.737455070181679
Human Diseases	Endocrine and metabolic disease	hsa04934	Cushing syndrome	2/202	155/9376	0.598914084956883	TCF7L2/PBX1	-0.747130049777206
Cellular Processes	Cell growth and death	hsa04110	Cell cycle	2/202	158/9376	0.587542298533651	YWHAE/MYC	-0.775838922882494
Organismal Systems	Digestive system	hsa04970	Salivary secretion	1/202	93/9376	0.499095070797402	CST3	-0.720335070481453
Environmental Information Processing	Signal transduction	hsa04070	Phosphatidylinositol signaling system	1/202	98/9376	0.473631036573045	INPP4B	-0.777245260732299
Organismal Systems	Endocrine system	hsa04925	Aldosterone synthesis and secretion	1/202	98/9376	0.473631036573045	NPR1	-0.777245260732299
Cellular Processes	Transport and catabolism	hsa04140	Autophagy - animal	2/202	169/9376	0.549299900404242	IRS2/HMGB1	-0.877311636497839
Organismal Systems	Sensory system	hsa04750	Inflammatory mediator regulation of TRP channels	1/202	99/9376	0.468846884688469	IGF1	-0.788343528877031
Human Diseases	Infectious disease: viral	hsa05164	Influenza A	2/202	173/9376	0.536599324672352	ACTB/HLA-DQA2	-0.912844825196277
Organismal Systems	Digestive system	hsa04972	Pancreatic secretion	1/202	102/9376	0.455057270432926	CPB1	-0.821106250049344
Genetic Information Processing	Translation	hsa03015	mRNA surveillance pathway	1/202	103/9376	0.45063923868115	PABPC1	-0.831855847335817
Human Diseases	Infectious disease: bacterial	hsa05152	Tuberculosis	2/202	181/9376	0.512882227449264	HLA-DQA2/EEA1	-0.981927336553722
Cellular Processes	Transport and catabolism	hsa04144	Endocytosis	3/202	250/9376	0.556990099009901	PDGFRA/PSD3/EEA1	-1.05347724585169
Organismal Systems	Nervous system	hsa04726	Serotonergic synapse	1/202	115/9376	0.403616013775291	GNG4	-0.954834069278617
Organismal Systems	Nervous system	hsa04724	Glutamatergic synapse	1/202	116/9376	0.400136565380676	GNG4	-0.964623518181016
Organismal Systems	Immune system	hsa04613	Neutrophil extracellular trap formation	2/202	195/9376	0.476059913683676	ACTB/HMGB1	-1.09707392840934
Organismal Systems	Immune system	hsa04650	Natural killer cell mediated cytotoxicity	1/202	133/9376	0.348991290106454	PTPN11	-1.12198770553808
Cellular Processes	Transport and catabolism	hsa04142	Lysosome biogenesis	2/202	250/9376	0.371326732673267	MITF/LITAF	-1.49498460581529
Cellular Processes	Cell growth and death	hsa04217	Necroptosis	1/202	168/9376	0.276284771334276	HMGB1	-1.40449970356145
Human Diseases	Substance dependence	hsa05034	Alcoholism	1/202	191/9376	0.243014877403971	GNG4	-1.56836232976892
Genetic Information Processing	Transcription	hsa03040	Spliceosome	1/202	243/9376	0.191011693761969	HNRNPA1	-1.89592261523294