ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0003735 structural constituent of ribosome 26/305 175/18639 0.148571428571429 9.07941920374707 1.03197102107244e-17 6.2640640979097e-15 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 11/305 68/18639 0.161764705882353 9.88567984570878 1.25918144048432e-08 3.82161567186991e-06 GO:0005539 glycosaminoglycan binding 18/305 242/18639 0.0743801652892562 4.54548164205392 1.04812881671445e-07 1.7667326088879e-05 GO:0005201 extracellular matrix structural constituent 15/305 168/18639 0.0892857142857143 5.45638173302108 1.1642389514912e-07 1.7667326088879e-05 GO:0008201 heparin binding 15/305 172/18639 0.0872093023255814 5.32948913457873 1.58688037612788e-07 1.92647277661925e-05 GO:0009055 electron transfer activity 12/305 116/18639 0.103448275862069 6.32187676653477 4.47967194261225e-07 4.53193478194273e-05 GO:0048027 mRNA 5'-UTR binding 6/305 24/18639 0.25 15.277868852459 1.91919062536506e-06 0.000166421244228085 GO:1901681 sulfur compound binding 17/305 275/18639 0.0618181818181818 3.77780029806259 3.10457584303325e-06 0.000235559692090148 GO:0022853 active monoatomic ion transmembrane transporter activity 11/305 118/18639 0.0932203389830508 5.69683245345929 3.80670222181096e-06 0.000248351298469701 GO:0008137 NADH dehydrogenase (ubiquinone) activity 7/305 41/18639 0.170731707317073 10.4336665333866 4.09145467001155e-06 0.000248351298469701 GO:0003954 NADH dehydrogenase activity 7/305 44/18639 0.159090909090909 9.72228017883756 6.68706284356587e-06 0.000369004286004044 GO:0015078 proton transmembrane transporter activity 13/305 185/18639 0.0702702702702703 4.29431989366416 1.17239675667723e-05 0.000593037359419234 GO:0005518 collagen binding 8/305 72/18639 0.111111111111111 6.79016393442623 2.26275339403512e-05 0.00105653177706101 GO:0043394 proteoglycan binding 6/305 37/18639 0.162162162162162 9.90996898537882 2.77174757283566e-05 0.00120175055479375 GO:0045296 cadherin binding 17/305 334/18639 0.0508982035928144 3.1104643172671 3.89284195850642e-05 0.00157530337920893 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 7/305 58/18639 0.120689655172414 7.37552289429056 4.31445494855099e-05 0.00163679634610653 GO:0019838 growth factor binding 10/305 136/18639 0.0735294117647059 4.49349083895853 8.20883880315106e-05 0.0029310383255957 GO:0015399 primary active transmembrane transporter activity 11/305 166/18639 0.0662650602409639 4.04955559944697 9.36901146875657e-05 0.00301540893446209 GO:0061134 peptidase regulator activity 13/305 226/18639 0.0575221238938053 3.51526185985783 9.43867706009552e-05 0.00301540893446209 GO:0005520 insulin-like growth factor binding 4/305 19/18639 0.210526315789474 12.8655737704918 0.000224404741527106 0.00681068390534767 GO:0004866 endopeptidase inhibitor activity 10/305 161/18639 0.062111801242236 3.79574381427553 0.000327408341241684 0.00946366014922393 GO:0030414 peptidase inhibitor activity 10/305 169/18639 0.0591715976331361 3.61606363371811 0.000480898479470274 0.0132684262290207 GO:0004857 enzyme inhibitor activity 17/305 416/18639 0.0408653846153846 2.49734394703657 0.000531367384310451 0.0140234783598454 GO:0042056 chemoattractant activity 5/305 42/18639 0.119047619047619 7.2751756440281 0.000588065742629514 0.0142464533754318 GO:0016651 oxidoreductase activity, acting on NAD(P)H 7/305 88/18639 0.0795454545454545 4.86114008941878 0.000600167710132251 0.0142464533754318 GO:0001221 transcription coregulator binding 8/305 115/18639 0.0695652173913043 4.2512330719886 0.000610226997959188 0.0142464533754318 GO:0030547 signaling receptor inhibitor activity 5/305 44/18639 0.113636363636364 6.94448584202682 0.000731017756212692 0.0164343621489298 GO:0043548 phosphatidylinositol 3-kinase binding 4/305 26/18639 0.153846153846154 9.40176544766709 0.000790895395335108 0.0171454823203004 GO:0061135 endopeptidase regulator activity 10/305 184/18639 0.0543478260869565 3.32127583749109 0.000929488571758956 0.0194551573468168 GO:0031994 insulin-like growth factor I binding 3/305 13/18639 0.230769230769231 14.1026481715006 0.00109866567360877 0.0222296687960175 GO:0005178 integrin binding 9/305 161/18639 0.0559006211180124 3.41616943284798 0.00136301999047537 0.0261234248864052 GO:0001968 fibronectin binding 4/305 30/18639 0.133333333333333 8.14819672131147 0.00137718220158973 0.0261234248864052 GO:0004129 cytochrome-c oxidase activity 3/305 15/18639 0.2 12.2222950819672 0.00170599605178696 0.0303343494222145 GO:0017046 peptide hormone binding 5/305 53/18639 0.0943396226415094 5.76523352922982 0.00171385644382994 0.0303343494222145 GO:0019199 transmembrane receptor protein kinase activity 6/305 78/18639 0.0769230769230769 4.70088272383354 0.00174909757788716 0.0303343494222145 GO:0016675 oxidoreductase activity, acting on a heme group of donors 3/305 16/18639 0.1875 11.4584016393443 0.00207441020207577 0.0349768609072221 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 17/305 484/18639 0.0351239669421488 2.14647744208102 0.00270605305605605 0.0437861986062972 GO:0004869 cysteine-type endopeptidase inhibitor activity 4/305 36/18639 0.111111111111111 6.79016393442623 0.00274114587650625 0.0437861986062972 GO:0001216 DNA-binding transcription activator activity 17/305 491/18639 0.0346232179226069 2.11587593068679 0.00313196684090912 0.0487462531392778 GO:0019843 rRNA binding 5/305 65/18639 0.0769230769230769 4.70088272383354 0.00420861872262361 0.0638657891158132 GO:0042562 hormone binding 6/305 94/18639 0.0638297872340425 3.90073247296826 0.00446453217072808 0.0660968543324865 GO:0010314 phosphatidylinositol-5-phosphate binding 3/305 21/18639 0.142857142857143 8.73021077283372 0.0046379180260872 0.0665570582626699 GO:0050840 extracellular matrix binding 5/305 67/18639 0.0746268656716418 4.56055786640568 0.00479264140865646 0.0665570582626699 GO:0008307 structural constituent of muscle 4/305 42/18639 0.0952380952380952 5.82014051522248 0.0048245643551194 0.0665570582626699 GO:0030021 extracellular matrix structural constituent conferring compression resistance 3/305 22/18639 0.136363636363636 8.33338301043219 0.00530588919778525 0.071570549845681 GO:0005158 insulin receptor binding 3/305 23/18639 0.130434782608696 7.97106200997862 0.00602873827178293 0.0795531332820052 GO:0005504 fatty acid binding 4/305 47/18639 0.0851063829787234 5.20097663062435 0.0072141572936152 0.088969269602802 GO:0005004 GPI-linked ephrin receptor activity 4/305 49/18639 0.0816326530612245 4.9886918701907 0.00835461016039492 0.088969269602802 GO:0005008 hepatocyte growth factor receptor activity 4/305 49/18639 0.0816326530612245 4.9886918701907 0.00835461016039492 0.088969269602802 GO:0005009 insulin receptor activity 4/305 49/18639 0.0816326530612245 4.9886918701907 0.00835461016039492 0.088969269602802 GO:0005011 macrophage colony-stimulating factor receptor activity 4/305 49/18639 0.0816326530612245 4.9886918701907 0.00835461016039492 0.088969269602802 GO:0005018 platelet-derived growth factor alpha-receptor activity 4/305 49/18639 0.0816326530612245 4.9886918701907 0.00835461016039492 0.088969269602802 GO:0005020 stem cell factor receptor activity 4/305 49/18639 0.0816326530612245 4.9886918701907 0.00835461016039492 0.088969269602802 GO:0008288 boss receptor activity 4/305 49/18639 0.0816326530612245 4.9886918701907 0.00835461016039492 0.088969269602802 GO:0036332 placental growth factor receptor activity 4/305 49/18639 0.0816326530612245 4.9886918701907 0.00835461016039492 0.088969269602802 GO:0038062 protein tyrosine kinase collagen receptor activity 4/305 49/18639 0.0816326530612245 4.9886918701907 0.00835461016039492 0.088969269602802 GO:0060175 brain-derived neurotrophic factor receptor activity 4/305 49/18639 0.0816326530612245 4.9886918701907 0.00835461016039492 0.088969269602802 GO:0005006 epidermal growth factor receptor activity 4/305 50/18639 0.08 4.88891803278689 0.00896659380197843 0.0892249579967362 GO:0005007 fibroblast growth factor receptor activity 4/305 50/18639 0.08 4.88891803278689 0.00896659380197843 0.0892249579967362 GO:0005017 platelet-derived growth factor receptor activity 4/305 50/18639 0.08 4.88891803278689 0.00896659380197843 0.0892249579967362 GO:0005019 platelet-derived growth factor beta-receptor activity 4/305 50/18639 0.08 4.88891803278689 0.00896659380197843 0.0892249579967362 GO:0005104 fibroblast growth factor receptor binding 3/305 27/18639 0.111111111111111 6.79016393442623 0.00948985332399365 0.0897155174418856 GO:0005010 insulin-like growth factor receptor activity 4/305 51/18639 0.0784313725490196 4.7930568948891 0.00960709824336501 0.0897155174418856 GO:0005021 vascular endothelial growth factor receptor activity 4/305 51/18639 0.0784313725490196 4.7930568948891 0.00960709824336501 0.0897155174418856 GO:0005030 neurotrophin receptor activity 4/305 51/18639 0.0784313725490196 4.7930568948891 0.00960709824336501 0.0897155174418856 GO:0005003 ephrin receptor activity 4/305 53/18639 0.0754716981132075 4.61218682338385 0.0109756147553385 0.0955490686196494 GO:0005005 transmembrane-ephrin receptor activity 4/305 53/18639 0.0754716981132075 4.61218682338385 0.0109756147553385 0.0955490686196494 GO:0038064 collagen receptor activity 4/305 53/18639 0.0754716981132075 4.61218682338385 0.0109756147553385 0.0955490686196494 GO:0030957 Tat protein binding 2/305 10/18639 0.2 12.2222950819672 0.0110123278542405 0.0955490686196494 GO:0008237 metallopeptidase activity 8/305 184/18639 0.0434782608695652 2.65702066999287 0.0110188382263187 0.0955490686196494 GO:0031625 ubiquitin protein ligase binding 11/305 302/18639 0.0364238410596026 2.22591466724568 0.0112992664390036 0.0960089922898831 GO:0004629 phospholipase C activity 3/305 29/18639 0.103448275862069 6.32187676653477 0.011574219046698 0.0960089922898831 GO:0043236 laminin binding 3/305 29/18639 0.103448275862069 6.32187676653477 0.011574219046698 0.0960089922898831 GO:0140463 chromatin-protein adaptor activity 4/305 54/18639 0.0740740740740741 4.52677595628415 0.0117045558969544 0.0960089922898831 GO:0140313 molecular sequestering activity 4/305 55/18639 0.0727272727272727 4.44447093889717 0.0124638756424783 0.100874300199791 GO:0048019 receptor antagonist activity 3/305 30/18639 0.1 6.11114754098361 0.0127072231405989 0.10149058482031 GO:0016176 superoxide-generating NADPH oxidase activator activity 2/305 11/18639 0.181818181818182 11.1111773472429 0.0133151936799585 0.102307880553605 GO:0048185 activin binding 2/305 11/18639 0.181818181818182 11.1111773472429 0.0133151936799585 0.102307880553605 GO:1990948 ubiquitin ligase inhibitor activity 2/305 11/18639 0.181818181818182 11.1111773472429 0.0133151936799585 0.102307880553605 GO:0003779 actin binding 14/305 443/18639 0.0316027088036117 1.93128816193613 0.0147805280900388 0.112147256883169 GO:0070888 E-box binding 4/305 59/18639 0.0677966101694915 4.14315087524312 0.0158130771800785 0.118500467263057 GO:0140311 protein sequestering activity 3/305 33/18639 0.0909090909090909 5.55558867362146 0.0164751875694401 0.121956571398172 GO:0004714 transmembrane receptor protein tyrosine kinase activity 4/305 60/18639 0.0666666666666667 4.07409836065574 0.0167302349416419 0.122352441079237 GO:0008083 growth factor activity 7/305 162/18639 0.0432098765432099 2.64061930783242 0.017437184474644 0.124534359238968 GO:0044389 ubiquitin-like protein ligase binding 11/305 322/18639 0.0341614906832298 2.08765909785154 0.017438913567236 0.124534359238968 GO:0015026 coreceptor activity 4/305 61/18639 0.0655737704918033 4.00730986294007 0.0176800231612706 0.124788070452224 GO:0045028 G protein-coupled purinergic nucleotide receptor activity 2/305 13/18639 0.153846153846154 9.40176544766709 0.0184814107133071 0.127479730715652 GO:0070123 transforming growth factor beta receptor activity, type III 2/305 13/18639 0.153846153846154 9.40176544766709 0.0184814107133071 0.127479730715652 GO:0004867 serine-type endopeptidase inhibitor activity 5/305 95/18639 0.0526315789473684 3.21639344262295 0.0199197384638612 0.135857092669255 GO:0008191 metalloendopeptidase inhibitor activity 2/305 14/18639 0.142857142857143 8.73021077283372 0.021331405678789 0.143868480522499 GO:0008235 metalloexopeptidase activity 4/305 66/18639 0.0606060606060606 3.70372578241431 0.0229287159099838 0.152942094036925 GO:0016500 protein-hormone receptor activity 4/305 67/18639 0.0597014925373134 3.64844629312454 0.0240802127037189 0.158877055556058 GO:0055105 ubiquitin-protein transferase inhibitor activity 2/305 15/18639 0.133333333333333 8.14819672131147 0.0243506994675585 0.158934135234495 GO:0008238 exopeptidase activity 5/305 102/18639 0.0490196078431373 2.99566055930569 0.02614414739515 0.168824441158043 GO:0005024 transforming growth factor beta receptor activity 2/305 16/18639 0.125 7.63893442622951 0.0275330265054847 0.174089032175304 GO:0005159 insulin-like growth factor receptor binding 2/305 16/18639 0.125 7.63893442622951 0.0275330265054847 0.174089032175304 GO:0008013 beta-catenin binding 5/305 106/18639 0.0471698113207547 2.88261676461491 0.0302016121200335 0.187199707369043 GO:0048038 quinone binding 2/305 17/18639 0.117647058823529 7.18958534233365 0.0308722797634879 0.187199707369043 GO:1990226 histone methyltransferase binding 2/305 17/18639 0.117647058823529 7.18958534233365 0.0308722797634879 0.187199707369043 GO:0031492 nucleosomal DNA binding 3/305 42/18639 0.0714285714285714 4.36510538641686 0.0311485509790334 0.187199707369043 GO:0035198 miRNA binding 3/305 42/18639 0.0714285714285714 4.36510538641686 0.0311485509790334 0.187199707369043 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 2/305 18/18639 0.111111111111111 6.79016393442623 0.0343625072745203 0.202147856235173 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 2/305 18/18639 0.111111111111111 6.79016393442623 0.0343625072745203 0.202147856235173 GO:0004222 metalloendopeptidase activity 5/305 110/18639 0.0454545454545455 2.77779433681073 0.0346348880534727 0.202147856235173 GO:1902936 phosphatidylinositol bisphosphate binding 5/305 111/18639 0.045045045045045 2.75276916260523 0.0358028129923116 0.206974357012697 GO:0005200 structural constituent of cytoskeleton 5/305 112/18639 0.0446428571428571 2.72819086651054 0.0369947810326771 0.210804401035665 GO:0008009 chemokine activity 3/305 45/18639 0.0666666666666667 4.07409836065574 0.0371599191281979 0.210804401035665 GO:0043395 heparan sulfate proteoglycan binding 2/305 19/18639 0.105263157894737 6.4327868852459 0.0379979087214876 0.213562320314287 GO:0033293 monocarboxylic acid binding 4/305 79/18639 0.0506329113924051 3.09425191948537 0.0406258754724107 0.222422009486884 GO:0046332 SMAD binding 4/305 79/18639 0.0506329113924051 3.09425191948537 0.0406258754724107 0.222422009486884 GO:0001614 purinergic nucleotide receptor activity 2/305 20/18639 0.1 6.11114754098361 0.041772832094736 0.222422009486884 GO:0016004 phospholipase activator activity 2/305 20/18639 0.1 6.11114754098361 0.041772832094736 0.222422009486884 GO:0016502 nucleotide receptor activity 2/305 20/18639 0.1 6.11114754098361 0.041772832094736 0.222422009486884 GO:0042288 MHC class I protein binding 2/305 20/18639 0.1 6.11114754098361 0.041772832094736 0.222422009486884 GO:0032266 phosphatidylinositol-3-phosphate binding 3/305 48/18639 0.0625 3.81946721311475 0.0437196386280067 0.23076365780174 GO:0017171 serine hydrolase activity 7/305 198/18639 0.0353535353535354 2.16050670640835 0.0447492313338629 0.234161926031507 GO:0008528 G protein-coupled peptide receptor activity 5/305 122/18639 0.040983606557377 2.50456866433754 0.0502527005486494 0.260712728487437 GO:0004022 alcohol dehydrogenase (NAD+) activity 2/305 23/18639 0.0869565217391304 5.31404133998574 0.0538803699938402 0.274835164590429 GO:0017134 fibroblast growth factor binding 2/305 23/18639 0.0869565217391304 5.31404133998574 0.0538803699938402 0.274835164590429 GO:0004864 protein phosphatase inhibitor activity 3/305 53/18639 0.0566037735849057 3.45914011753789 0.0558368732257844 0.281621789267844 GO:0001664 G protein-coupled receptor binding 9/305 297/18639 0.0303030303030303 1.85186289120715 0.0562967016531396 0.281621789267844 GO:0051015 actin filament binding 7/305 209/18639 0.0334928229665072 2.0467958271237 0.056701014483926 0.281621789267844 GO:0050431 transforming growth factor beta binding 2/305 24/18639 0.0833333333333333 5.09262295081967 0.0581597139195251 0.281621789267844 GO:0060229 lipase activator activity 2/305 24/18639 0.0833333333333333 5.09262295081967 0.0581597139195251 0.281621789267844 GO:0051287 NAD binding 3/305 54/18639 0.0555555555555556 3.39508196721311 0.0584328918921861 0.281621789267844 GO:0140297 DNA-binding transcription factor binding 13/305 488/18639 0.0266393442622951 1.6279696318194 0.0590085113116271 0.281621789267844 GO:0001653 peptide receptor activity 5/305 128/18639 0.0390625 2.38716700819672 0.0593864728604351 0.281621789267844 GO:0031490 chromatin DNA binding 5/305 128/18639 0.0390625 2.38716700819672 0.0593864728604351 0.281621789267844 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 10/305 349/18639 0.0286532951289398 1.75104514068298 0.0620455437257827 0.291950736756202 GO:0016298 lipase activity 5/305 130/18639 0.0384615384615385 2.35044136191677 0.0626279733094482 0.292424459991039 GO:0019212 phosphatase inhibitor activity 3/305 56/18639 0.0535714285714286 3.27382903981265 0.0637923631398924 0.294939082033629 GO:0005543 phospholipid binding 13/305 497/18639 0.0261569416498994 1.59848929643434 0.0661046421212696 0.294939082033629 GO:0016504 peptidase activator activity 3/305 57/18639 0.0526315789473684 3.21639344262295 0.0665544214167864 0.294939082033629 GO:0004435 phosphatidylinositol phospholipase C activity 2/305 26/18639 0.0769230769230769 4.70088272383354 0.0670536957506439 0.294939082033629 GO:0005160 transforming growth factor beta receptor binding 2/305 26/18639 0.0769230769230769 4.70088272383354 0.0670536957506439 0.294939082033629 GO:0050750 low-density lipoprotein particle receptor binding 2/305 26/18639 0.0769230769230769 4.70088272383354 0.0670536957506439 0.294939082033629 GO:0070006 metalloaminopeptidase activity 2/305 26/18639 0.0769230769230769 4.70088272383354 0.0670536957506439 0.294939082033629 GO:0070412 R-SMAD binding 2/305 26/18639 0.0769230769230769 4.70088272383354 0.0670536957506439 0.294939082033629 GO:0061980 regulatory RNA binding 3/305 58/18639 0.0517241379310345 3.16093838326738 0.0693703960571447 0.302429371122103 GO:0004252 serine-type endopeptidase activity 6/305 176/18639 0.0340909090909091 2.08334575260805 0.0697530674746202 0.302429371122103 GO:0015252 proton channel activity 2/305 27/18639 0.0740740740740741 4.52677595628415 0.0716588031447759 0.304174080481671 GO:0023026 MHC class II protein complex binding 2/305 27/18639 0.0740740740740741 4.52677595628415 0.0716588031447759 0.304174080481671 GO:0035255 ionotropic glutamate receptor binding 2/305 27/18639 0.0740740740740741 4.52677595628415 0.0716588031447759 0.304174080481671 GO:0001786 phosphatidylserine binding 3/305 59/18639 0.0508474576271186 3.10736315643234 0.0722395381398446 0.304509719797817 GO:0022804 active transmembrane transporter activity 12/305 457/18639 0.0262582056892779 1.60467769128672 0.0737721283239164 0.308825392362878 GO:0045499 chemorepellent activity 2/305 28/18639 0.0714285714285714 4.36510538641686 0.0763631762633128 0.315322775454632 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 2/305 28/18639 0.0714285714285714 4.36510538641686 0.0763631762633128 0.315322775454632 GO:0070851 growth factor receptor binding 5/305 139/18639 0.0359712230215827 2.19825451114518 0.0784231206401579 0.321640771814702 GO:0004713 protein tyrosine kinase activity 5/305 140/18639 0.0357142857142857 2.18255269320843 0.0802989297808929 0.326261930301791 GO:0003785 actin monomer binding 2/305 29/18639 0.0689655172413793 4.21458451102318 0.0811623582793582 0.326261930301791 GO:0004181 metallocarboxypeptidase activity 2/305 29/18639 0.0689655172413793 4.21458451102318 0.0811623582793582 0.326261930301791 GO:1901981 phosphatidylinositol phosphate binding 6/305 185/18639 0.0324324324324324 1.98199379707576 0.0840055796469811 0.334176061681194 GO:0005507 copper ion binding 3/305 63/18639 0.0476190476190476 2.91007025761124 0.0842321868817507 0.334176061681194 GO:0038024 cargo receptor activity 3/305 65/18639 0.0461538461538462 2.82052963430013 0.0905268117785676 0.351935936745054 GO:0017147 Wnt-protein binding 2/305 31/18639 0.0645161290322581 3.94267583289265 0.0910279111515214 0.351935936745054 GO:0070273 phosphatidylinositol-4-phosphate binding 2/305 31/18639 0.0645161290322581 3.94267583289265 0.0910279111515214 0.351935936745054 GO:0070325 lipoprotein particle receptor binding 2/305 31/18639 0.0645161290322581 3.94267583289265 0.0910279111515214 0.351935936745054 GO:0019888 protein phosphatase regulator activity 4/305 107/18639 0.0373831775700935 2.2845411368163 0.0987773036954727 0.379479894576911 GO:0008236 serine-type peptidase activity 6/305 194/18639 0.0309278350515464 1.89004563123204 0.099750314265989 0.380599084801879 GO:1990841 promoter-specific chromatin binding 3/305 68/18639 0.0441176470588235 2.69609450337512 0.100322658267382 0.380599084801879 GO:0071889 14-3-3 protein binding 2/305 33/18639 0.0606060606060606 3.70372578241431 0.10122212809411 0.3816262841809 GO:0004620 phospholipase activity 4/305 109/18639 0.036697247706422 2.24262295081967 0.103915800355648 0.389363523554804 GO:0090482 vitamin transmembrane transporter activity 2/305 34/18639 0.0588235294117647 3.59479267116683 0.106432555014267 0.396322852489234 GO:0097110 scaffold protein binding 3/305 70/18639 0.0428571428571429 2.61906323185012 0.107078991446844 0.396322852489234 GO:0033218 amide binding 7/305 247/18639 0.0283400809716599 1.73190416141236 0.111952166247948 0.411848272196997 GO:0042379 chemokine receptor binding 3/305 72/18639 0.0416666666666667 2.54631147540984 0.114007635192939 0.416883340735625 GO:0055106 ubiquitin-protein transferase regulator activity 2/305 36/18639 0.0555555555555556 3.39508196721311 0.117061117745526 0.424662683965477 GO:0043539 protein serine/threonine kinase activator activity 3/305 73/18639 0.0410958904109589 2.51143049629463 0.117534317802636 0.424662683965477 GO:0003714 transcription corepressor activity 6/305 204/18639 0.0294117647058824 1.79739633558341 0.118938782229178 0.426105873140506 GO:0035401 histone H3Y41 kinase activity 4/305 115/18639 0.0347826086956522 2.1256165359943 0.120039710555233 0.426105873140506 GO:0140801 histone H2AXY142 kinase activity 4/305 115/18639 0.0347826086956522 2.1256165359943 0.120039710555233 0.426105873140506 GO:0031491 nucleosome binding 3/305 74/18639 0.0405405405405405 2.47749224634471 0.121101361585832 0.427375153968605 GO:0023023 MHC protein complex binding 2/305 37/18639 0.0540540540540541 3.30332299512627 0.122471990742693 0.429713863472917 GO:0019208 phosphatase regulator activity 4/305 117/18639 0.0341880341880342 2.08928121059269 0.125641136683287 0.438299827395145 GO:0005501 retinoid binding 2/305 38/18639 0.0526315789473684 3.21639344262295 0.127942582172648 0.441256519197713 GO:0019840 isoprenoid binding 2/305 38/18639 0.0526315789473684 3.21639344262295 0.127942582172648 0.441256519197713 GO:0000217 DNA secondary structure binding 2/305 39/18639 0.0512820512820513 3.13392181588903 0.133469506059975 0.450654017828939 GO:0016776 phosphotransferase activity, phosphate group as acceptor 2/305 39/18639 0.0512820512820513 3.13392181588903 0.133469506059975 0.450654017828939 GO:0004177 aminopeptidase activity 2/305 40/18639 0.05 3.0555737704918 0.139049470587833 0.450654017828939 GO:0071949 FAD binding 2/305 40/18639 0.05 3.0555737704918 0.139049470587833 0.450654017828939 GO:0003730 mRNA 3'-UTR binding 7/305 262/18639 0.0267175572519084 1.63274934301089 0.139558860501 0.450654017828939 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 4/305 122/18639 0.0327868852459016 2.00365493147003 0.140112618468697 0.450654017828939 GO:0042287 MHC protein binding 2/305 41/18639 0.0487804878048781 2.98104758096761 0.144679275940021 0.450654017828939 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 7/305 268/18639 0.0261194029850746 1.59619525324199 0.151450624168609 0.450654017828939 GO:0003680 minor groove of adenine-thymine-rich DNA binding 1/305 10/18639 0.1 6.11114754098361 0.152131036628255 0.450654017828939 GO:0004935 adrenergic receptor activity 1/305 10/18639 0.1 6.11114754098361 0.152131036628255 0.450654017828939 GO:0004955 prostaglandin receptor activity 1/305 10/18639 0.1 6.11114754098361 0.152131036628255 0.450654017828939 GO:0005522 profilin binding 1/305 10/18639 0.1 6.11114754098361 0.152131036628255 0.450654017828939 GO:0015279 store-operated calcium channel activity 1/305 10/18639 0.1 6.11114754098361 0.152131036628255 0.450654017828939 GO:0032395 MHC class II receptor activity 1/305 10/18639 0.1 6.11114754098361 0.152131036628255 0.450654017828939 GO:0034596 phosphatidylinositol phosphate 4-phosphatase activity 1/305 10/18639 0.1 6.11114754098361 0.152131036628255 0.450654017828939 GO:0035374 chondroitin sulfate binding 1/305 10/18639 0.1 6.11114754098361 0.152131036628255 0.450654017828939 GO:0050815 phosphoserine residue binding 1/305 10/18639 0.1 6.11114754098361 0.152131036628255 0.450654017828939 GO:0098505 G-rich strand telomeric DNA binding 1/305 10/18639 0.1 6.11114754098361 0.152131036628255 0.450654017828939 GO:0001540 amyloid-beta binding 3/305 83/18639 0.036144578313253 2.20884850878926 0.154869532944442 0.450654017828939 GO:0048156 tau protein binding 2/305 43/18639 0.0465116279069767 2.84239420510865 0.156076057222499 0.450654017828939 GO:0035591 signaling adaptor activity 4/305 129/18639 0.0310077519379845 1.89492947007244 0.161418392697151 0.450654017828939 GO:0001046 core promoter sequence-specific DNA binding 2/305 44/18639 0.0454545454545455 2.77779433681073 0.161837074727334 0.450654017828939 GO:0001223 transcription coactivator binding 2/305 44/18639 0.0454545454545455 2.77779433681073 0.161837074727334 0.450654017828939 GO:0005126 cytokine receptor binding 7/305 275/18639 0.0254545454545455 1.55556482861401 0.165900807204081 0.450654017828939 GO:0001851 complement component C3b binding 1/305 11/18639 0.0909090909090909 5.55558867362146 0.166012620923085 0.450654017828939 GO:0002162 dystroglycan binding 1/305 11/18639 0.0909090909090909 5.55558867362146 0.166012620923085 0.450654017828939 GO:0004954 prostanoid receptor activity 1/305 11/18639 0.0909090909090909 5.55558867362146 0.166012620923085 0.450654017828939 GO:0005114 type II transforming growth factor beta receptor binding 1/305 11/18639 0.0909090909090909 5.55558867362146 0.166012620923085 0.450654017828939 GO:0005536 D-glucose binding 1/305 11/18639 0.0909090909090909 5.55558867362146 0.166012620923085 0.450654017828939 GO:0008503 benzodiazepine receptor activity 1/305 11/18639 0.0909090909090909 5.55558867362146 0.166012620923085 0.450654017828939 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 1/305 11/18639 0.0909090909090909 5.55558867362146 0.166012620923085 0.450654017828939 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives 1/305 11/18639 0.0909090909090909 5.55558867362146 0.166012620923085 0.450654017828939 GO:0032794 GTPase activating protein binding 1/305 11/18639 0.0909090909090909 5.55558867362146 0.166012620923085 0.450654017828939 GO:0034056 estrogen response element binding 1/305 11/18639 0.0909090909090909 5.55558867362146 0.166012620923085 0.450654017828939 GO:0034713 type I transforming growth factor beta receptor binding 1/305 11/18639 0.0909090909090909 5.55558867362146 0.166012620923085 0.450654017828939 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding 1/305 11/18639 0.0909090909090909 5.55558867362146 0.166012620923085 0.450654017828939 GO:0043522 leucine zipper domain binding 1/305 11/18639 0.0909090909090909 5.55558867362146 0.166012620923085 0.450654017828939 GO:0045294 alpha-catenin binding 1/305 11/18639 0.0909090909090909 5.55558867362146 0.166012620923085 0.450654017828939 GO:0048407 platelet-derived growth factor binding 1/305 11/18639 0.0909090909090909 5.55558867362146 0.166012620923085 0.450654017828939 GO:0050786 RAGE receptor binding 1/305 11/18639 0.0909090909090909 5.55558867362146 0.166012620923085 0.450654017828939 GO:0050998 nitric-oxide synthase binding 1/305 11/18639 0.0909090909090909 5.55558867362146 0.166012620923085 0.450654017828939 GO:0097493 structural molecule activity conferring elasticity 1/305 11/18639 0.0909090909090909 5.55558867362146 0.166012620923085 0.450654017828939 GO:0098973 structural constituent of postsynaptic actin cytoskeleton 1/305 11/18639 0.0909090909090909 5.55558867362146 0.166012620923085 0.450654017828939 GO:0140031 phosphorylation-dependent protein binding 1/305 11/18639 0.0909090909090909 5.55558867362146 0.166012620923085 0.450654017828939 GO:0140537 transcription regulator activator activity 1/305 11/18639 0.0909090909090909 5.55558867362146 0.166012620923085 0.450654017828939 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 3/305 86/18639 0.0348837209302326 2.13179565383149 0.166719737040371 0.450654017828939 GO:0008081 phosphoric diester hydrolase activity 3/305 87/18639 0.0344827586206897 2.10729225551159 0.170727882055474 0.450654017828939 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 4/305 132/18639 0.0303030303030303 1.85186289120715 0.170892210620047 0.450654017828939 GO:0001217 DNA-binding transcription repressor activity 7/305 278/18639 0.0251798561151079 1.53877815780163 0.172275906374792 0.450654017828939 GO:0004180 carboxypeptidase activity 2/305 46/18639 0.0434782608695652 2.65702066999287 0.173470098995155 0.450654017828939 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 2/305 46/18639 0.0434782608695652 2.65702066999287 0.173470098995155 0.450654017828939 GO:0051087 protein-folding chaperone binding 4/305 134/18639 0.0298507462686567 1.82422314656227 0.177313934014571 0.450654017828939 GO:0004859 phospholipase inhibitor activity 1/305 12/18639 0.0833333333333333 5.09262295081967 0.179667664439215 0.450654017828939 GO:0005025 transforming growth factor beta receptor activity, type I 1/305 12/18639 0.0833333333333333 5.09262295081967 0.179667664439215 0.450654017828939 GO:0005026 transforming growth factor beta receptor activity, type II 1/305 12/18639 0.0833333333333333 5.09262295081967 0.179667664439215 0.450654017828939 GO:0005078 MAP-kinase scaffold activity 1/305 12/18639 0.0833333333333333 5.09262295081967 0.179667664439215 0.450654017828939 GO:0008179 adenylate cyclase binding 1/305 12/18639 0.0833333333333333 5.09262295081967 0.179667664439215 0.450654017828939 GO:0016361 activin receptor activity, type I 1/305 12/18639 0.0833333333333333 5.09262295081967 0.179667664439215 0.450654017828939 GO:0016362 activin receptor activity, type II 1/305 12/18639 0.0833333333333333 5.09262295081967 0.179667664439215 0.450654017828939 GO:0017002 activin receptor activity 1/305 12/18639 0.0833333333333333 5.09262295081967 0.179667664439215 0.450654017828939 GO:0035014 phosphatidylinositol 3-kinase regulator activity 1/305 12/18639 0.0833333333333333 5.09262295081967 0.179667664439215 0.450654017828939 GO:0035497 cAMP response element binding 1/305 12/18639 0.0833333333333333 5.09262295081967 0.179667664439215 0.450654017828939 GO:0043047 single-stranded telomeric DNA binding 1/305 12/18639 0.0833333333333333 5.09262295081967 0.179667664439215 0.450654017828939 GO:0045295 gamma-catenin binding 1/305 12/18639 0.0833333333333333 5.09262295081967 0.179667664439215 0.450654017828939 GO:0070679 inositol 1,4,5 trisphosphate binding 1/305 12/18639 0.0833333333333333 5.09262295081967 0.179667664439215 0.450654017828939 GO:1990459 transferrin receptor binding 1/305 12/18639 0.0833333333333333 5.09262295081967 0.179667664439215 0.450654017828939 GO:0002020 protease binding 4/305 136/18639 0.0294117647058824 1.79739633558341 0.183816344804848 0.455752811670222 GO:0140693 molecular condensate scaffold activity 2/305 48/18639 0.0416666666666667 2.54631147540984 0.185233036010997 0.455752811670222 GO:0035091 phosphatidylinositol binding 7/305 284/18639 0.0246478873239437 1.50626876010159 0.185338751178471 0.455752811670222 GO:0072341 modified amino acid binding 3/305 91/18639 0.032967032967033 2.01466402450009 0.187026749961506 0.455752811670222 GO:0001222 transcription corepressor binding 2/305 49/18639 0.0408163265306122 2.49434593509535 0.191156737393249 0.455752811670222 GO:0035254 glutamate receptor binding 2/305 49/18639 0.0408163265306122 2.49434593509535 0.191156737393249 0.455752811670222 GO:0060590 ATPase regulator activity 2/305 49/18639 0.0408163265306122 2.49434593509535 0.191156737393249 0.455752811670222 GO:0031406 carboxylic acid binding 5/305 187/18639 0.0267379679144385 1.63399666871219 0.192744351928337 0.455752811670222 GO:0015651 quaternary ammonium group transmembrane transporter activity 1/305 13/18639 0.0769230769230769 4.70088272383354 0.193099852249707 0.455752811670222 GO:0017154 semaphorin receptor activity 1/305 13/18639 0.0769230769230769 4.70088272383354 0.193099852249707 0.455752811670222 GO:0019855 calcium channel inhibitor activity 1/305 13/18639 0.0769230769230769 4.70088272383354 0.193099852249707 0.455752811670222 GO:0039706 co-receptor binding 1/305 13/18639 0.0769230769230769 4.70088272383354 0.193099852249707 0.455752811670222 GO:0043560 insulin receptor substrate binding 1/305 13/18639 0.0769230769230769 4.70088272383354 0.193099852249707 0.455752811670222 GO:0045159 myosin II binding 1/305 13/18639 0.0769230769230769 4.70088272383354 0.193099852249707 0.455752811670222 GO:1901338 catecholamine binding 1/305 13/18639 0.0769230769230769 4.70088272383354 0.193099852249707 0.455752811670222 GO:0030295 protein kinase activator activity 4/305 139/18639 0.0287769784172662 1.75860360891615 0.193713715668727 0.455752811670222 GO:0048020 CCR chemokine receptor binding 2/305 50/18639 0.04 2.44445901639344 0.197105286828076 0.460411306892247 GO:0043177 organic acid binding 5/305 189/18639 0.0264550264550265 1.61670569867291 0.198423052049716 0.460411306892247 GO:0030544 Hsp70 protein binding 2/305 51/18639 0.0392156862745098 2.39652844744455 0.203076295300568 0.460411306892247 GO:0004065 arylsulfatase activity 1/305 14/18639 0.0714285714285714 4.36510538641686 0.206312809678239 0.460411306892247 GO:0005161 platelet-derived growth factor receptor binding 1/305 14/18639 0.0714285714285714 4.36510538641686 0.206312809678239 0.460411306892247 GO:0005545 1-phosphatidylinositol binding 1/305 14/18639 0.0714285714285714 4.36510538641686 0.206312809678239 0.460411306892247 GO:0008494 translation activator activity 1/305 14/18639 0.0714285714285714 4.36510538641686 0.206312809678239 0.460411306892247 GO:0032036 myosin heavy chain binding 1/305 14/18639 0.0714285714285714 4.36510538641686 0.206312809678239 0.460411306892247 GO:0042043 neurexin family protein binding 1/305 14/18639 0.0714285714285714 4.36510538641686 0.206312809678239 0.460411306892247 GO:0046030 inositol trisphosphate phosphatase activity 1/305 14/18639 0.0714285714285714 4.36510538641686 0.206312809678239 0.460411306892247 GO:0098821 BMP receptor activity 1/305 14/18639 0.0714285714285714 4.36510538641686 0.206312809678239 0.460411306892247 GO:0098847 sequence-specific single stranded DNA binding 1/305 14/18639 0.0714285714285714 4.36510538641686 0.206312809678239 0.460411306892247 GO:1901474 azole transmembrane transporter activity 1/305 14/18639 0.0714285714285714 4.36510538641686 0.206312809678239 0.460411306892247 GO:1901612 cardiolipin binding 1/305 14/18639 0.0714285714285714 4.36510538641686 0.206312809678239 0.460411306892247 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 2/305 52/18639 0.0384615384615385 2.35044136191677 0.209067444844247 0.463153062118461 GO:0030159 signaling receptor complex adaptor activity 2/305 52/18639 0.0384615384615385 2.35044136191677 0.209067444844247 0.463153062118461 GO:0019903 protein phosphatase binding 4/305 144/18639 0.0277777777777778 1.69754098360656 0.21056382713577 0.464771792986955 GO:0005246 calcium channel regulator activity 2/305 53/18639 0.0377358490566038 2.30609341169193 0.215076486868501 0.467092044497132 GO:0051018 protein kinase A binding 2/305 53/18639 0.0377358490566038 2.30609341169193 0.215076486868501 0.467092044497132 GO:0000774 adenyl-nucleotide exchange factor activity 1/305 15/18639 0.0666666666666667 4.07409836065574 0.219310103264716 0.467092044497132 GO:0004865 protein serine/threonine phosphatase inhibitor activity 1/305 15/18639 0.0666666666666667 4.07409836065574 0.219310103264716 0.467092044497132 GO:0004953 icosanoid receptor activity 1/305 15/18639 0.0666666666666667 4.07409836065574 0.219310103264716 0.467092044497132 GO:0005523 tropomyosin binding 1/305 15/18639 0.0666666666666667 4.07409836065574 0.219310103264716 0.467092044497132 GO:0042809 nuclear vitamin D receptor binding 1/305 15/18639 0.0666666666666667 4.07409836065574 0.219310103264716 0.467092044497132 GO:0045504 dynein heavy chain binding 1/305 15/18639 0.0666666666666667 4.07409836065574 0.219310103264716 0.467092044497132 GO:0051371 muscle alpha-actinin binding 1/305 15/18639 0.0666666666666667 4.07409836065574 0.219310103264716 0.467092044497132 GO:0120283 protein serine/threonine kinase binding 1/305 15/18639 0.0666666666666667 4.07409836065574 0.219310103264716 0.467092044497132 GO:0004175 endopeptidase activity 9/305 405/18639 0.0222222222222222 1.35803278688525 0.220483625323502 0.467949512487292 GO:0019209 kinase activator activity 4/305 148/18639 0.027027027027027 1.65166149756314 0.224331741173824 0.472757757453712 GO:0042277 peptide binding 6/305 249/18639 0.0240963855421687 1.47256567252617 0.224381121739893 0.472757757453712 GO:0141003 histone H2AX kinase activity 8/305 354/18639 0.0225988700564972 1.38105029174771 0.225107183844015 0.472757757453712 GO:0098632 cell-cell adhesion mediator activity 2/305 55/18639 0.0363636363636364 2.22223546944858 0.227139591087453 0.472757757453712 GO:0140996 histone H3 kinase activity 8/305 357/18639 0.0224089635854342 1.36944482711117 0.231716300999309 0.472757757453712 GO:0004708 MAP kinase kinase activity 1/305 16/18639 0.0625 3.81946721311475 0.232095241715331 0.472757757453712 GO:0005324 long-chain fatty acid transmembrane transporter activity 1/305 16/18639 0.0625 3.81946721311475 0.232095241715331 0.472757757453712 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 1/305 16/18639 0.0625 3.81946721311475 0.232095241715331 0.472757757453712 GO:0030275 LRR domain binding 1/305 16/18639 0.0625 3.81946721311475 0.232095241715331 0.472757757453712 GO:0031435 mitogen-activated protein kinase kinase kinase binding 1/305 16/18639 0.0625 3.81946721311475 0.232095241715331 0.472757757453712 GO:0055102 lipase inhibitor activity 1/305 16/18639 0.0625 3.81946721311475 0.232095241715331 0.472757757453712 GO:0099507 ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential 1/305 16/18639 0.0625 3.81946721311475 0.232095241715331 0.472757757453712 GO:0035173 histone kinase activity 8/305 360/18639 0.0222222222222222 1.35803278688525 0.238393653204772 0.483963035101325 GO:0004029 aldehyde dehydrogenase (NAD+) activity 1/305 17/18639 0.0588235294117647 3.59479267116683 0.244671676837322 0.485345450458347 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 1/305 17/18639 0.0588235294117647 3.59479267116683 0.244671676837322 0.485345450458347 GO:0008484 sulfuric ester hydrolase activity 1/305 17/18639 0.0588235294117647 3.59479267116683 0.244671676837322 0.485345450458347 GO:0030169 low-density lipoprotein particle binding 1/305 17/18639 0.0588235294117647 3.59479267116683 0.244671676837322 0.485345450458347 GO:0045125 bioactive lipid receptor activity 1/305 17/18639 0.0588235294117647 3.59479267116683 0.244671676837322 0.485345450458347 GO:0070403 NAD+ binding 1/305 17/18639 0.0588235294117647 3.59479267116683 0.244671676837322 0.485345450458347 GO:0070492 oligosaccharide binding 1/305 17/18639 0.0588235294117647 3.59479267116683 0.244671676837322 0.485345450458347 GO:0004497 monooxygenase activity 3/305 106/18639 0.0283018867924528 1.72957005876895 0.25111321917355 0.488380282440763 GO:0004879 nuclear receptor activity 2/305 59/18639 0.0338983050847458 2.07157543762156 0.251388896038509 0.488380282440763 GO:0036002 pre-mRNA binding 2/305 59/18639 0.0338983050847458 2.07157543762156 0.251388896038509 0.488380282440763 GO:0045309 protein phosphorylated amino acid binding 2/305 59/18639 0.0338983050847458 2.07157543762156 0.251388896038509 0.488380282440763 GO:0000400 four-way junction DNA binding 1/305 18/18639 0.0555555555555556 3.39508196721311 0.257042804458663 0.488380282440763 GO:0003746 translation elongation factor activity 1/305 18/18639 0.0555555555555556 3.39508196721311 0.257042804458663 0.488380282440763 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity 1/305 18/18639 0.0555555555555556 3.39508196721311 0.257042804458663 0.488380282440763 GO:0016854 racemase and epimerase activity 1/305 18/18639 0.0555555555555556 3.39508196721311 0.257042804458663 0.488380282440763 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 1/305 18/18639 0.0555555555555556 3.39508196721311 0.257042804458663 0.488380282440763 GO:0022851 GABA-gated chloride ion channel activity 1/305 18/18639 0.0555555555555556 3.39508196721311 0.257042804458663 0.488380282440763 GO:0031690 adrenergic receptor binding 1/305 18/18639 0.0555555555555556 3.39508196721311 0.257042804458663 0.488380282440763 GO:0070064 proline-rich region binding 1/305 18/18639 0.0555555555555556 3.39508196721311 0.257042804458663 0.488380282440763 GO:1901611 phosphatidylglycerol binding 1/305 18/18639 0.0555555555555556 3.39508196721311 0.257042804458663 0.488380282440763 GO:0098531 ligand-modulated transcription factor activity 2/305 60/18639 0.0333333333333333 2.03704918032787 0.257465717266959 0.488380282440763 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 1/305 19/18639 0.0526315789473684 3.21639344262295 0.26921196533295 0.50280511679108 GO:0004890 GABA-A receptor activity 1/305 19/18639 0.0526315789473684 3.21639344262295 0.26921196533295 0.50280511679108 GO:0008301 DNA binding, bending 1/305 19/18639 0.0526315789473684 3.21639344262295 0.26921196533295 0.50280511679108 GO:0015245 fatty acid transmembrane transporter activity 1/305 19/18639 0.0526315789473684 3.21639344262295 0.26921196533295 0.50280511679108 GO:0050145 nucleoside monophosphate kinase activity 1/305 19/18639 0.0526315789473684 3.21639344262295 0.26921196533295 0.50280511679108 GO:0005525 GTP binding 8/305 378/18639 0.0211640211640212 1.29336455893833 0.279735898884469 0.512545780000081 GO:0001972 retinoic acid binding 1/305 20/18639 0.05 3.0555737704918 0.281182446029698 0.512545780000081 GO:0004745 all-trans-retinol dehydrogenase (NAD+) activity 1/305 20/18639 0.05 3.0555737704918 0.281182446029698 0.512545780000081 GO:0016408 C-acyltransferase activity 1/305 20/18639 0.05 3.0555737704918 0.281182446029698 0.512545780000081 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 1/305 20/18639 0.05 3.0555737704918 0.281182446029698 0.512545780000081 GO:0030742 GTP-dependent protein binding 1/305 20/18639 0.05 3.0555737704918 0.281182446029698 0.512545780000081 GO:0043024 ribosomal small subunit binding 1/305 20/18639 0.05 3.0555737704918 0.281182446029698 0.512545780000081 GO:0052745 inositol phosphate phosphatase activity 1/305 20/18639 0.05 3.0555737704918 0.281182446029698 0.512545780000081 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 1/305 21/18639 0.0476190476190476 2.91007025761124 0.292957479810296 0.520630080566352 GO:0001846 opsonin binding 1/305 21/18639 0.0476190476190476 2.91007025761124 0.292957479810296 0.520630080566352 GO:0008373 sialyltransferase activity 1/305 21/18639 0.0476190476190476 2.91007025761124 0.292957479810296 0.520630080566352 GO:0009975 cyclase activity 1/305 21/18639 0.0476190476190476 2.91007025761124 0.292957479810296 0.520630080566352 GO:0036122 BMP binding 1/305 21/18639 0.0476190476190476 2.91007025761124 0.292957479810296 0.520630080566352 GO:0051428 peptide hormone receptor binding 1/305 21/18639 0.0476190476190476 2.91007025761124 0.292957479810296 0.520630080566352 GO:0070182 DNA polymerase binding 1/305 21/18639 0.0476190476190476 2.91007025761124 0.292957479810296 0.520630080566352 GO:0072542 protein phosphatase activator activity 1/305 21/18639 0.0476190476190476 2.91007025761124 0.292957479810296 0.520630080566352 GO:0003712 transcription coregulator activity 10/305 495/18639 0.0202020202020202 1.23457526080477 0.293336882296034 0.520630080566352 GO:0005243 gap junction channel activity 1/305 22/18639 0.0454545454545455 2.77779433681073 0.304540247489846 0.537371890192838 GO:0008093 cytoskeletal anchor activity 1/305 22/18639 0.0454545454545455 2.77779433681073 0.304540247489846 0.537371890192838 GO:0030246 carbohydrate binding 6/305 280/18639 0.0214285714285714 1.30953161592506 0.309924334933434 0.545287163201724 GO:0003887 DNA-directed DNA polymerase activity 1/305 23/18639 0.0434782608695652 2.65702066999287 0.315933878285119 0.546358587233809 GO:0005212 structural constituent of eye lens 1/305 23/18639 0.0434782608695652 2.65702066999287 0.315933878285119 0.546358587233809 GO:0016849 phosphorus-oxygen lyase activity 1/305 23/18639 0.0434782608695652 2.65702066999287 0.315933878285119 0.546358587233809 GO:0016917 GABA receptor activity 1/305 23/18639 0.0434782608695652 2.65702066999287 0.315933878285119 0.546358587233809 GO:0031681 G-protein beta-subunit binding 1/305 23/18639 0.0434782608695652 2.65702066999287 0.315933878285119 0.546358587233809 GO:0099186 structural constituent of postsynapse 1/305 23/18639 0.0434782608695652 2.65702066999287 0.315933878285119 0.546358587233809 GO:0003697 single-stranded DNA binding 3/305 121/18639 0.0247933884297521 1.51516054735131 0.317822776413718 0.546511119782229 GO:0051082 unfolded protein binding 3/305 121/18639 0.0247933884297521 1.51516054735131 0.317822776413718 0.546511119782229 GO:0004806 triacylglycerol lipase activity 1/305 24/18639 0.0416666666666667 2.54631147540984 0.32714145064884 0.553133316278122 GO:0005540 hyaluronic acid binding 1/305 24/18639 0.0416666666666667 2.54631147540984 0.32714145064884 0.553133316278122 GO:0015149 hexose transmembrane transporter activity 1/305 24/18639 0.0416666666666667 2.54631147540984 0.32714145064884 0.553133316278122 GO:0030215 semaphorin receptor binding 1/305 24/18639 0.0416666666666667 2.54631147540984 0.32714145064884 0.553133316278122 GO:0050699 WW domain binding 1/305 24/18639 0.0416666666666667 2.54631147540984 0.32714145064884 0.553133316278122 GO:0055056 D-glucose transmembrane transporter activity 1/305 24/18639 0.0416666666666667 2.54631147540984 0.32714145064884 0.553133316278122 GO:0019207 kinase regulator activity 6/305 287/18639 0.0209059233449477 1.27759182041469 0.330043168027181 0.556489452756942 GO:0019001 guanyl nucleotide binding 8/305 400/18639 0.02 1.22222950819672 0.332573602377963 0.557657946528794 GO:0032561 guanyl ribonucleotide binding 8/305 400/18639 0.02 1.22222950819672 0.332573602377963 0.557657946528794 GO:0005125 cytokine activity 5/305 234/18639 0.0213675213675214 1.30580075662043 0.337294478417984 0.557790102733568 GO:0001848 complement binding 1/305 25/18639 0.04 2.44445901639344 0.338165993090532 0.557790102733568 GO:0003707 nuclear steroid receptor activity 1/305 25/18639 0.04 2.44445901639344 0.338165993090532 0.557790102733568 GO:0005537 D-mannose binding 1/305 25/18639 0.04 2.44445901639344 0.338165993090532 0.557790102733568 GO:0008483 transaminase activity 1/305 25/18639 0.04 2.44445901639344 0.338165993090532 0.557790102733568 GO:0019211 phosphatase activator activity 1/305 25/18639 0.04 2.44445901639344 0.338165993090532 0.557790102733568 GO:0003684 damaged DNA binding 2/305 74/18639 0.027027027027027 1.65166149756314 0.342073314525226 0.559672511905154 GO:0035064 methylated histone binding 2/305 74/18639 0.027027027027027 1.65166149756314 0.342073314525226 0.559672511905154 GO:0048029 monosaccharide binding 2/305 74/18639 0.027027027027027 1.65166149756314 0.342073314525226 0.559672511905154 GO:0008143 poly(A) binding 1/305 26/18639 0.0384615384615385 2.35044136191677 0.349010484984128 0.56644215076301 GO:0015145 monosaccharide transmembrane transporter activity 1/305 26/18639 0.0384615384615385 2.35044136191677 0.349010484984128 0.56644215076301 GO:0019865 immunoglobulin binding 1/305 26/18639 0.0384615384615385 2.35044136191677 0.349010484984128 0.56644215076301 GO:0017022 myosin binding 2/305 76/18639 0.0263157894736842 1.60819672131148 0.353965712651878 0.568405258147328 GO:0051536 iron-sulfur cluster binding 2/305 76/18639 0.0263157894736842 1.60819672131148 0.353965712651878 0.568405258147328 GO:0098631 cell adhesion mediator activity 2/305 76/18639 0.0263157894736842 1.60819672131148 0.353965712651878 0.568405258147328 GO:0140034 methylation-dependent protein binding 2/305 76/18639 0.0263157894736842 1.60819672131148 0.353965712651878 0.568405258147328 GO:0001671 ATPase activator activity 1/305 27/18639 0.037037037037037 2.26338797814208 0.359677857362565 0.570364224223716 GO:0005044 scavenger receptor activity 1/305 27/18639 0.037037037037037 2.26338797814208 0.359677857362565 0.570364224223716 GO:0008266 poly(U) RNA binding 1/305 27/18639 0.037037037037037 2.26338797814208 0.359677857362565 0.570364224223716 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity 1/305 27/18639 0.037037037037037 2.26338797814208 0.359677857362565 0.570364224223716 GO:0051540 metal cluster binding 2/305 77/18639 0.025974025974026 1.58731104960613 0.359883851528308 0.570364224223716 GO:0031072 heat shock protein binding 3/305 131/18639 0.0229007633587786 1.39949943686647 0.362569658733818 0.573124434508925 GO:0005179 hormone activity 3/305 132/18639 0.0227272727272727 1.38889716840537 0.36702727380623 0.576137931219594 GO:0046875 ephrin receptor binding 1/305 28/18639 0.0357142857142857 2.18255269320843 0.370170993699574 0.576137931219594 GO:0051119 sugar transmembrane transporter activity 1/305 28/18639 0.0357142857142857 2.18255269320843 0.370170993699574 0.576137931219594 GO:0051393 alpha-actinin binding 1/305 28/18639 0.0357142857142857 2.18255269320843 0.370170993699574 0.576137931219594 GO:0051537 2 iron, 2 sulfur cluster binding 1/305 28/18639 0.0357142857142857 2.18255269320843 0.370170993699574 0.576137931219594 GO:0097718 disordered domain specific binding 1/305 28/18639 0.0357142857142857 2.18255269320843 0.370170993699574 0.576137931219594 GO:0019902 phosphatase binding 4/305 190/18639 0.0210526315789474 1.28655737704918 0.377491691979842 0.582609426002973 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 1/305 29/18639 0.0344827586206897 2.10729225551159 0.380492730678867 0.582609426002973 GO:0106222 lncRNA binding 1/305 29/18639 0.0344827586206897 2.10729225551159 0.380492730678867 0.582609426002973 GO:0001618 virus receptor activity 2/305 81/18639 0.0246913580246914 1.50892531876138 0.383347226972097 0.582609426002973 GO:0030971 receptor tyrosine kinase binding 2/305 81/18639 0.0246913580246914 1.50892531876138 0.383347226972097 0.582609426002973 GO:0042578 phosphoric ester hydrolase activity 7/305 363/18639 0.0192837465564738 1.17845820349546 0.383844252656432 0.582609426002973 GO:0140789 histone phosphatase activity 3/305 136/18639 0.0220588235294118 1.34804725168756 0.384799857799693 0.582609426002973 GO:0140272 exogenous protein binding 2/305 82/18639 0.024390243902439 1.49052379048381 0.389156393107478 0.582609426002973 GO:0016922 nuclear receptor binding 3/305 137/18639 0.0218978102189781 1.33820749072634 0.389226047163119 0.582609426002973 GO:0001965 G-protein alpha-subunit binding 1/305 30/18639 0.0333333333333333 2.03704918032787 0.390645858950923 0.582609426002973 GO:0008187 poly-pyrimidine tract binding 1/305 30/18639 0.0333333333333333 2.03704918032787 0.390645858950923 0.582609426002973 GO:0015215 nucleotide transmembrane transporter activity 1/305 30/18639 0.0333333333333333 2.03704918032787 0.390645858950923 0.582609426002973 GO:0016769 transferase activity, transferring nitrogenous groups 1/305 30/18639 0.0333333333333333 2.03704918032787 0.390645858950923 0.582609426002973 GO:0031210 phosphatidylcholine binding 1/305 30/18639 0.0333333333333333 2.03704918032787 0.390645858950923 0.582609426002973 GO:0035925 mRNA 3'-UTR AU-rich region binding 1/305 30/18639 0.0333333333333333 2.03704918032787 0.390645858950923 0.582609426002973 GO:0051721 protein phosphatase 2A binding 1/305 30/18639 0.0333333333333333 2.03704918032787 0.390645858950923 0.582609426002973 GO:0098918 structural constituent of synapse 1/305 30/18639 0.0333333333333333 2.03704918032787 0.390645858950923 0.582609426002973 GO:0008135 translation factor activity, RNA binding 2/305 83/18639 0.0240963855421687 1.47256567252617 0.394941253852245 0.586135308284383 GO:0030165 PDZ domain binding 2/305 83/18639 0.0240963855421687 1.47256567252617 0.394941253852245 0.586135308284383 GO:0046982 protein heterodimerization activity 7/305 369/18639 0.018970189701897 1.15929628148741 0.399901457566077 0.590353244546048 GO:0047499 calcium-independent phospholipase A2 activity 1/305 31/18639 0.032258064516129 1.97133791644632 0.400633123877569 0.590353244546048 GO:0180051 translation factor activity 2/305 84/18639 0.0238095238095238 1.45503512880562 0.400701049016428 0.590353244546048 GO:0019887 protein kinase regulator activity 5/305 255/18639 0.0196078431372549 1.19826422372228 0.405345844682892 0.595750430320861 GO:0003713 transcription coactivator activity 5/305 256/18639 0.01953125 1.19358350409836 0.408579201988762 0.596046737661711 GO:0031369 translation initiation factor binding 1/305 32/18639 0.03125 1.90973360655738 0.410457226264572 0.596046737661711 GO:0070717 poly-purine tract binding 1/305 32/18639 0.03125 1.90973360655738 0.410457226264572 0.596046737661711 GO:0071813 lipoprotein particle binding 1/305 32/18639 0.03125 1.90973360655738 0.410457226264572 0.596046737661711 GO:0071814 protein-lipid complex binding 1/305 32/18639 0.03125 1.90973360655738 0.410457226264572 0.596046737661711 GO:0050660 flavin adenine dinucleotide binding 2/305 86/18639 0.0232558139534884 1.42119710255433 0.412142557057546 0.597065709150193 GO:0019955 cytokine binding 3/305 144/18639 0.0208333333333333 1.27315573770492 0.419967228062588 0.605732398125929 GO:0019956 chemokine binding 1/305 33/18639 0.0303030303030303 1.85186289120715 0.420120823082399 0.605732398125929 GO:0003727 single-stranded RNA binding 2/305 89/18639 0.0224719101123595 1.37329158224351 0.429099573890039 0.609306781781427 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 2/305 89/18639 0.0224719101123595 1.37329158224351 0.429099573890039 0.609306781781427 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 2/305 89/18639 0.0224719101123595 1.37329158224351 0.429099573890039 0.609306781781427 GO:0008376 acetylgalactosaminyltransferase activity 1/305 34/18639 0.0294117647058824 1.79739633558341 0.429626528175372 0.609306781781427 GO:0019825 oxygen binding 1/305 34/18639 0.0294117647058824 1.79739633558341 0.429626528175372 0.609306781781427 GO:0051427 hormone receptor binding 1/305 34/18639 0.0294117647058824 1.79739633558341 0.429626528175372 0.609306781781427 GO:0052866 phosphatidylinositol phosphate phosphatase activity 1/305 34/18639 0.0294117647058824 1.79739633558341 0.429626528175372 0.609306781781427 GO:0140793 histone H2AXY142 phosphatase activity 2/305 90/18639 0.0222222222222222 1.35803278688525 0.434694703252449 0.615057540499386 GO:0004623 phospholipase A2 activity 1/305 35/18639 0.0285714285714286 1.74604215456674 0.438976912959383 0.618234306650453 GO:0034061 DNA polymerase activity 1/305 35/18639 0.0285714285714286 1.74604215456674 0.438976912959383 0.618234306650453 GO:0005516 calmodulin binding 4/305 207/18639 0.0193236714975845 1.18089807555239 0.440008405536167 0.618252551297345 GO:0043178 alcohol binding 2/305 92/18639 0.0217391304347826 1.32851033499644 0.445795757551041 0.623497753072539 GO:0052689 carboxylic ester hydrolase activity 2/305 92/18639 0.0217391304347826 1.32851033499644 0.445795757551041 0.623497753072539 GO:0016409 palmitoyltransferase activity 1/305 36/18639 0.0277777777777778 1.69754098360656 0.44817450710835 0.625383737505215 GO:0051219 phosphoprotein binding 2/305 93/18639 0.021505376344086 1.31422527763088 0.451300643101592 0.628301583400611 GO:0016410 N-acyltransferase activity 2/305 94/18639 0.0212765957446809 1.30024415765609 0.456774449313279 0.629327964018998 GO:0019213 deacetylase activity 1/305 37/18639 0.027027027027027 1.65166149756314 0.457221799229618 0.629327964018998 GO:0022829 wide pore channel activity 1/305 37/18639 0.027027027027027 1.65166149756314 0.457221799229618 0.629327964018998 GO:0030280 structural constituent of skin epidermis 1/305 37/18639 0.027027027027027 1.65166149756314 0.457221799229618 0.629327964018998 GO:0042805 actinin binding 1/305 37/18639 0.027027027027027 1.65166149756314 0.457221799229618 0.629327964018998 GO:0005506 iron ion binding 3/305 154/18639 0.0194805194805195 1.1904832872046 0.462936406769262 0.635752033730638 GO:0005109 frizzled binding 1/305 38/18639 0.0263157894736842 1.60819672131148 0.466121237528455 0.635810317257915 GO:0042162 telomeric DNA binding 1/305 38/18639 0.0263157894736842 1.60819672131148 0.466121237528455 0.635810317257915 GO:0043531 ADP binding 1/305 38/18639 0.0263157894736842 1.60819672131148 0.466121237528455 0.635810317257915 GO:0004725 protein tyrosine phosphatase activity 2/305 98/18639 0.0204081632653061 1.24717296754767 0.478350050807257 0.651027983946199 GO:0015144 carbohydrate transmembrane transporter activity 1/305 40/18639 0.025 1.5277868852459 0.483486147381683 0.653621584544947 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 1/305 40/18639 0.025 1.5277868852459 0.483486147381683 0.653621584544947 GO:0050997 quaternary ammonium group binding 1/305 40/18639 0.025 1.5277868852459 0.483486147381683 0.653621584544947 GO:0001530 lipopolysaccharide binding 1/305 41/18639 0.024390243902439 1.49052379048381 0.491956319167724 0.659199747758959 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 1/305 41/18639 0.024390243902439 1.49052379048381 0.491956319167724 0.659199747758959 GO:0008227 G protein-coupled amine receptor activity 1/305 41/18639 0.024390243902439 1.49052379048381 0.491956319167724 0.659199747758959 GO:0042169 SH2 domain binding 1/305 41/18639 0.024390243902439 1.49052379048381 0.491956319167724 0.659199747758959 GO:0019894 kinesin binding 1/305 42/18639 0.0238095238095238 1.45503512880562 0.500288038850155 0.668887311854723 GO:0004712 protein serine/threonine/tyrosine kinase activity 1/305 43/18639 0.0232558139534884 1.42119710255433 0.508483562222242 0.6768629874318 GO:0008200 ion channel inhibitor activity 1/305 43/18639 0.0232558139534884 1.42119710255433 0.508483562222242 0.6768629874318 GO:0016248 channel inhibitor activity 1/305 44/18639 0.0227272727272727 1.38889716840537 0.516545108443053 0.683099958224256 GO:0019205 nucleobase-containing compound kinase activity 1/305 44/18639 0.0227272727272727 1.38889716840537 0.516545108443053 0.683099958224256 GO:0030020 extracellular matrix structural constituent conferring tensile strength 1/305 44/18639 0.0227272727272727 1.38889716840537 0.516545108443053 0.683099958224256 GO:0042605 peptide antigen binding 1/305 45/18639 0.0222222222222222 1.35803278688525 0.524474860630463 0.689082771434396 GO:0051539 4 iron, 4 sulfur cluster binding 1/305 45/18639 0.0222222222222222 1.35803278688525 0.524474860630463 0.689082771434396 GO:0141110 transporter inhibitor activity 1/305 45/18639 0.0222222222222222 1.35803278688525 0.524474860630463 0.689082771434396 GO:0005496 steroid binding 2/305 108/18639 0.0185185185185185 1.13169398907104 0.529927117406777 0.694742462777351 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 1/305 46/18639 0.0217391304347826 1.32851033499644 0.53227496644458 0.696316604810044 GO:0001784 phosphotyrosine residue binding 1/305 47/18639 0.0212765957446809 1.30024415765609 0.53994753866178 0.702407899399499 GO:0099095 ligand-gated monoatomic anion channel activity 1/305 47/18639 0.0212765957446809 1.30024415765609 0.53994753866178 0.702407899399499 GO:0140030 modification-dependent protein binding 3/305 173/18639 0.0173410404624277 1.05973656780063 0.540402782569302 0.702407899399499 GO:0004721 phosphoprotein phosphatase activity 3/305 175/18639 0.0171428571428571 1.04762529274005 0.548182848676293 0.704046178878681 GO:0043022 ribosome binding 2/305 112/18639 0.0178571428571429 1.09127634660422 0.549568643879116 0.704046178878681 GO:0043021 ribonucleoprotein complex binding 3/305 177/18639 0.0169491525423729 1.03578771881078 0.555885552081803 0.704046178878681 GO:0015605 organophosphate ester transmembrane transporter activity 1/305 50/18639 0.02 1.22222950819672 0.562220670035824 0.704046178878681 GO:0017124 SH3 domain binding 2/305 115/18639 0.0173913043478261 1.06280826799715 0.56391829917728 0.704046178878681 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 4/305 243/18639 0.0164609053497942 1.00595021250759 0.564726569301163 0.704046178878681 GO:0003743 translation initiation factor activity 1/305 51/18639 0.0196078431372549 1.19826422372228 0.56940355753053 0.704046178878681 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 3/305 181/18639 0.0165745856353591 1.01289738248347 0.571053968122577 0.704046178878681 GO:0004676 3-phosphoinositide-dependent protein kinase activity 4/305 245/18639 0.0163265306122449 0.99773837403814 0.571214474815491 0.704046178878681 GO:0004711 ribosomal protein S6 kinase activity 4/305 245/18639 0.0163265306122449 0.99773837403814 0.571214474815491 0.704046178878681 GO:0035175 histone H3S10 kinase activity 4/305 245/18639 0.0163265306122449 0.99773837403814 0.571214474815491 0.704046178878681 GO:0035979 histone H2AXS139 kinase activity 4/305 245/18639 0.0163265306122449 0.99773837403814 0.571214474815491 0.704046178878681 GO:0044022 histone H3S28 kinase activity 4/305 245/18639 0.0163265306122449 0.99773837403814 0.571214474815491 0.704046178878681 GO:0044023 histone H4S1 kinase activity 4/305 245/18639 0.0163265306122449 0.99773837403814 0.571214474815491 0.704046178878681 GO:0044024 histone H2AS1 kinase activity 4/305 245/18639 0.0163265306122449 0.99773837403814 0.571214474815491 0.704046178878681 GO:0044025 histone H2BS14 kinase activity 4/305 245/18639 0.0163265306122449 0.99773837403814 0.571214474815491 0.704046178878681 GO:0072354 histone H3T3 kinase activity 4/305 245/18639 0.0163265306122449 0.99773837403814 0.571214474815491 0.704046178878681 GO:0072371 histone H2AS121 kinase activity 4/305 245/18639 0.0163265306122449 0.99773837403814 0.571214474815491 0.704046178878681 GO:0072518 Rho-dependent protein serine/threonine kinase activity 4/305 245/18639 0.0163265306122449 0.99773837403814 0.571214474815491 0.704046178878681 GO:0140823 histone H2BS36 kinase activity 4/305 245/18639 0.0163265306122449 0.99773837403814 0.571214474815491 0.704046178878681 GO:0140855 histone H3S57 kinase activity 4/305 245/18639 0.0163265306122449 0.99773837403814 0.571214474815491 0.704046178878681 GO:0140995 histone H2A kinase activity 4/305 245/18639 0.0163265306122449 0.99773837403814 0.571214474815491 0.704046178878681 GO:0140997 histone H4 kinase activity 4/305 245/18639 0.0163265306122449 0.99773837403814 0.571214474815491 0.704046178878681 GO:0140998 histone H2B kinase activity 4/305 245/18639 0.0163265306122449 0.99773837403814 0.571214474815491 0.704046178878681 GO:1990244 histone H2AT120 kinase activity 4/305 245/18639 0.0163265306122449 0.99773837403814 0.571214474815491 0.704046178878681 GO:1990782 protein tyrosine kinase binding 2/305 117/18639 0.0170940170940171 1.04464060529634 0.573301474110823 0.704046178878681 GO:0004677 DNA-dependent protein kinase activity 4/305 246/18639 0.016260162601626 0.993682526989204 0.574438233345653 0.704046178878681 GO:0140857 histone H3T45 kinase activity 4/305 246/18639 0.016260162601626 0.993682526989204 0.574438233345653 0.704046178878681 GO:0035402 histone H3T11 kinase activity 4/305 247/18639 0.0161943319838057 0.989659520807062 0.577648383493267 0.704046178878681 GO:0035403 histone H3T6 kinase activity 4/305 247/18639 0.0161943319838057 0.989659520807062 0.577648383493267 0.704046178878681 GO:0042393 histone binding 4/305 247/18639 0.0161943319838057 0.989659520807062 0.577648383493267 0.704046178878681 GO:0004679 AMP-activated protein kinase activity 4/305 248/18639 0.0161290322580645 0.985668958223162 0.580844820045591 0.704046178878681 GO:0008146 sulfotransferase activity 1/305 53/18639 0.0188679245283019 1.15304670584596 0.583418826978545 0.704046178878681 GO:0016860 intramolecular oxidoreductase activity 1/305 53/18639 0.0188679245283019 1.15304670584596 0.583418826978545 0.704046178878681 GO:0140296 general transcription initiation factor binding 1/305 53/18639 0.0188679245283019 1.15304670584596 0.583418826978545 0.704046178878681 GO:1904315 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential 1/305 53/18639 0.0188679245283019 1.15304670584596 0.583418826978545 0.704046178878681 GO:0015485 cholesterol binding 1/305 54/18639 0.0185185185185185 1.13169398907104 0.590255007855094 0.709474831223846 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 1/305 54/18639 0.0185185185185185 1.13169398907104 0.590255007855094 0.709474831223846 GO:0030170 pyridoxal phosphate binding 1/305 56/18639 0.0178571428571429 1.09127634660422 0.603593728861338 0.721223215391402 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential 1/305 56/18639 0.0178571428571429 1.09127634660422 0.603593728861338 0.721223215391402 GO:0170055 lipid transmembrane transporter activity 1/305 56/18639 0.0178571428571429 1.09127634660422 0.603593728861338 0.721223215391402 GO:0015932 nucleobase-containing compound transmembrane transporter activity 1/305 57/18639 0.0175438596491228 1.07213114754098 0.610099885708849 0.726138491422101 GO:0070279 vitamin B6 binding 1/305 57/18639 0.0175438596491228 1.07213114754098 0.610099885708849 0.726138491422101 GO:0042826 histone deacetylase binding 2/305 127/18639 0.015748031496063 0.962385439524977 0.618003735984594 0.734106199104988 GO:0015459 potassium channel regulator activity 1/305 59/18639 0.0169491525423729 1.03578771881078 0.622794614540536 0.738352209035362 GO:0003924 GTPase activity 5/305 331/18639 0.0151057401812689 0.923134069634986 0.633175308459948 0.749195735351245 GO:0016829 lyase activity 3/305 200/18639 0.015 0.916672131147541 0.63858067387871 0.754121535105792 GO:0022824 transmitter-gated monoatomic ion channel activity 1/305 63/18639 0.0158730158730159 0.970023419203747 0.646961354970495 0.759585188524353 GO:0022835 transmitter-gated channel activity 1/305 63/18639 0.0158730158730159 0.970023419203747 0.646961354970495 0.759585188524353 GO:1901682 sulfur compound transmembrane transporter activity 1/305 63/18639 0.0158730158730159 0.970023419203747 0.646961354970495 0.759585188524353 GO:0016779 nucleotidyltransferase activity 2/305 136/18639 0.0147058823529412 0.898698167791707 0.655089566682445 0.76581473648654 GO:0044325 transmembrane transporter binding 2/305 136/18639 0.0147058823529412 0.898698167791707 0.655089566682445 0.76581473648654 GO:0016791 phosphatase activity 4/305 273/18639 0.0146520146520147 0.895406233111151 0.65605216305272 0.76581473648654 GO:0160215 deacylase activity 1/305 65/18639 0.0153846153846154 0.940176544766709 0.658459596044524 0.767149663721739 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 1/305 67/18639 0.0149253731343284 0.912111573281135 0.669584534712007 0.778616499176606 GO:0032934 sterol binding 1/305 68/18639 0.0147058823529412 0.898698167791707 0.675010806352801 0.783425543893213 GO:0020037 heme binding 2/305 142/18639 0.0140845070422535 0.860725005772339 0.678184120829135 0.785116709115959 GO:0008080 N-acetyltransferase activity 1/305 69/18639 0.0144927536231884 0.885673556664291 0.680348252051062 0.785116709115959 GO:0098960 postsynaptic neurotransmitter receptor activity 1/305 69/18639 0.0144927536231884 0.885673556664291 0.680348252051062 0.785116709115959 GO:0008028 monocarboxylic acid transmembrane transporter activity 1/305 70/18639 0.0142857142857143 0.873021077283372 0.685598321147692 0.788178372986078 GO:0016782 transferase activity, transferring sulphur-containing groups 1/305 70/18639 0.0142857142857143 0.873021077283372 0.685598321147692 0.788178372986078 GO:0004521 RNA endonuclease activity 1/305 73/18639 0.0136986301369863 0.837143498764878 0.70083841094941 0.802658331030739 GO:0005230 extracellular ligand-gated monoatomic ion channel activity 1/305 73/18639 0.0136986301369863 0.837143498764878 0.70083841094941 0.802658331030739 GO:0044183 protein folding chaperone 1/305 75/18639 0.0133333333333333 0.814819672131148 0.710587115752539 0.812290733073053 GO:0046906 tetrapyrrole binding 2/305 152/18639 0.0131578947368421 0.804098360655738 0.71386374715122 0.814502433309757 GO:0004674 protein serine/threonine kinase activity 6/305 433/18639 0.0138568129330254 0.84681028281528 0.715258660276603 0.814562864517632 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 3/305 229/18639 0.0131004366812227 0.800587014102656 0.726641346733966 0.818921664334989 GO:0140375 immune receptor activity 2/305 156/18639 0.0128205128205128 0.783480453972257 0.727182031257608 0.818921664334989 GO:0000287 magnesium ion binding 3/305 230/18639 0.0130434782608696 0.797106200997862 0.729355022284232 0.818921664334989 GO:0005085 guanyl-nucleotide exchange factor activity 3/305 230/18639 0.0130434782608696 0.797106200997862 0.729355022284232 0.818921664334989 GO:0048306 calcium-dependent protein binding 1/305 80/18639 0.0125 0.763893442622951 0.733595781684284 0.818921664334989 GO:0015101 organic cation transmembrane transporter activity 1/305 81/18639 0.0123456790123457 0.754462659380692 0.737973888618186 0.818921664334989 GO:0033192 calmodulin-dependent protein phosphatase activity 1/305 81/18639 0.0123456790123457 0.754462659380692 0.737973888618186 0.818921664334989 GO:0140791 histone H2AXS140 phosphatase activity 1/305 81/18639 0.0123456790123457 0.754462659380692 0.737973888618186 0.818921664334989 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 1/305 81/18639 0.0123456790123457 0.754462659380692 0.737973888618186 0.818921664334989 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 1/305 81/18639 0.0123456790123457 0.754462659380692 0.737973888618186 0.818921664334989 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 1/305 81/18639 0.0123456790123457 0.754462659380692 0.737973888618186 0.818921664334989 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 1/305 81/18639 0.0123456790123457 0.754462659380692 0.737973888618186 0.818921664334989 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 1/305 81/18639 0.0123456790123457 0.754462659380692 0.737973888618186 0.818921664334989 GO:1990439 MAP kinase serine/threonine phosphatase activity 1/305 81/18639 0.0123456790123457 0.754462659380692 0.737973888618186 0.818921664334989 GO:0099106 ion channel regulator activity 2/305 160/18639 0.0125 0.763893442622951 0.739973123154977 0.819207506205732 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 1/305 82/18639 0.0121951219512195 0.745261895241903 0.742280277451652 0.819207506205732 GO:0033549 MAP kinase phosphatase activity 1/305 82/18639 0.0121951219512195 0.745261895241903 0.742280277451652 0.819207506205732 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 1/305 83/18639 0.0120481927710843 0.736282836263085 0.746516119202864 0.820897254268367 GO:0005254 chloride channel activity 1/305 83/18639 0.0120481927710843 0.736282836263085 0.746516119202864 0.820897254268367 GO:0017018 myosin phosphatase activity 1/305 84/18639 0.0119047619047619 0.72751756440281 0.750682565831616 0.822498767977962 GO:0051117 ATPase binding 1/305 84/18639 0.0119047619047619 0.72751756440281 0.750682565831616 0.822498767977962 GO:0016874 ligase activity 2/305 167/18639 0.0119760479041916 0.731873957004025 0.761127672697245 0.832440535724735 GO:0016247 channel regulator activity 2/305 168/18639 0.0119047619047619 0.72751756440281 0.764025315932391 0.834106774767916 GO:0141108 transporter regulator activity 2/305 170/18639 0.0117647058823529 0.718958534233365 0.769729419613258 0.838825417783209 GO:0005319 lipid transporter activity 2/305 178/18639 0.0112359550561798 0.686645791121754 0.791362238728554 0.860854621699341 GO:0004896 cytokine receptor activity 1/305 96/18639 0.0104166666666667 0.636577868852459 0.795661715797756 0.861792218083005 GO:0016407 acetyltransferase activity 1/305 96/18639 0.0104166666666667 0.636577868852459 0.795661715797756 0.861792218083005 GO:0016853 isomerase activity 2/305 180/18639 0.0111111111111111 0.679016393442623 0.796483417371608 0.861792218083005 GO:0030594 neurotransmitter receptor activity 1/305 97/18639 0.0103092783505155 0.630015210410681 0.79902272408561 0.863001411957234 GO:0004722 protein serine/threonine phosphatase activity 1/305 103/18639 0.00970873786407767 0.593315295241127 0.818062590544784 0.880391518337385 GO:0005253 monoatomic anion channel activity 1/305 103/18639 0.00970873786407767 0.593315295241127 0.818062590544784 0.880391518337385 GO:0008514 organic anion transmembrane transporter activity 3/305 269/18639 0.0111524163568773 0.681540617953562 0.819474807019148 0.880391518337385 GO:0031267 small GTPase binding 3/305 283/18639 0.0106007067137809 0.647824827666107 0.844962464313936 0.904817735280151 GO:0106310 protein serine kinase activity 4/305 361/18639 0.0110803324099723 0.677135461604832 0.845192184355594 0.904817735280151 GO:0004540 RNA nuclease activity 1/305 121/18639 0.00826446280991736 0.505053515783769 0.865053240069345 0.922824809704907 GO:0015108 chloride transmembrane transporter activity 1/305 121/18639 0.00826446280991736 0.505053515783769 0.865053240069345 0.922824809704907 GO:0004519 endonuclease activity 1/305 127/18639 0.0078740157480315 0.481192719762489 0.877853503061087 0.934836976066807 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 1/305 128/18639 0.0078125 0.477433401639344 0.87986596425201 0.935339124870351 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 1/305 130/18639 0.00769230769230769 0.470088272383354 0.883792277702907 0.9378704765134 GO:0005262 calcium channel activity 1/305 131/18639 0.00763358778625954 0.466499812288825 0.885707203160826 0.93826225535536 GO:0051020 GTPase binding 3/305 315/18639 0.00952380952380952 0.582014051522248 0.891793763215845 0.942758070066987 GO:0015297 antiporter activity 1/305 135/18639 0.00740740740740741 0.452677595628415 0.893057479882236 0.942758070066987 GO:0030695 GTPase regulator activity 5/305 489/18639 0.0102249488752556 0.624861711757015 0.905339682035653 0.953376557617831 GO:0060589 nucleoside-triphosphatase regulator activity 5/305 490/18639 0.0102040816326531 0.623586483773837 0.906257452628482 0.953376557617831 GO:0008194 UDP-glycosyltransferase activity 1/305 145/18639 0.00689655172413793 0.421458451102318 0.909436799951 0.955065981955462 GO:0015085 calcium ion transmembrane transporter activity 1/305 147/18639 0.00680272108843537 0.415724322515892 0.912399354685161 0.956522294117258 GO:0008509 monoatomic anion transmembrane transporter activity 1/305 149/18639 0.00671140939597315 0.410144130267356 0.915265304013772 0.957684102302933 GO:0019842 vitamin binding 1/305 150/18639 0.00666666666666667 0.407409836065574 0.916663036965411 0.957684102302933 GO:0005261 monoatomic cation channel activity 3/305 341/18639 0.00879765395894428 0.53763761357627 0.920073398900967 0.959595452118362 GO:0045182 translation regulator activity 3/305 356/18639 0.00842696629213483 0.514984343341315 0.933152054474853 0.970236440316506 GO:0016757 glycosyltransferase activity 2/305 267/18639 0.00749063670411985 0.457763860747836 0.934856539895989 0.970236440316506 GO:0015103 inorganic anion transmembrane transporter activity 1/305 165/18639 0.00606060606060606 0.370372578241431 0.935071363402234 0.970236440316506 GO:0005216 monoatomic ion channel activity 4/305 448/18639 0.00892857142857143 0.545638173302108 0.937672784931062 0.970287978316913 GO:0005096 GTPase activator activity 2/305 271/18639 0.00738007380073801 0.451007198596576 0.938318028454741 0.970287978316913 GO:0003823 antigen binding 1/305 174/18639 0.00574712643678161 0.351215375918598 0.944107589123559 0.974614467003402 GO:0015276 ligand-gated monoatomic ion channel activity 1/305 186/18639 0.00537634408602151 0.328556319407721 0.954235876690284 0.980702758474889 GO:0022834 ligand-gated channel activity 1/305 188/18639 0.00531914893617021 0.325061039414022 0.955736237267075 0.980702758474889 GO:0046943 carboxylic acid transmembrane transporter activity 1/305 188/18639 0.00531914893617021 0.325061039414022 0.955736237267075 0.980702758474889 GO:0005342 organic acid transmembrane transporter activity 1/305 189/18639 0.00529100529100529 0.323341139734582 0.95646792918803 0.980702758474889 GO:0016758 hexosyltransferase activity 1/305 197/18639 0.0050761421319797 0.31021053507531 0.961903676885285 0.984613038565544 GO:0004518 nuclease activity 1/305 209/18639 0.00478468899521531 0.292399403874814 0.968814972064779 0.990017993338924 GO:0008017 microtubule binding 1/305 276/18639 0.0036231884057971 0.221418389166073 0.989825880623505 0.999666860252109 GO:0015291 secondary active transmembrane transporter activity 1/305 287/18639 0.00348432055749129 0.212931970069115 0.99153823403289 0.999666860252109 GO:0022836 gated channel activity 1/305 318/18639 0.00314465408805031 0.192174450974327 0.994969108163746 0.999666860252109 GO:0140097 catalytic activity, acting on DNA 1/305 336/18639 0.00297619047619048 0.181879391100703 0.996281659876965 0.999666860252109 GO:0061630 ubiquitin protein ligase activity 1/305 353/18639 0.0028328611898017 0.173120326940046 0.997205990710223 0.999666860252109 GO:0016755 aminoacyltransferase activity 2/305 496/18639 0.00403225806451613 0.246417239555791 0.997632222261777 0.999666860252109 GO:0061659 ubiquitin-like protein ligase activity 1/305 372/18639 0.00268817204301075 0.16427815970386 0.997970606352131 0.999666860252109 GO:0015631 tubulin binding 1/305 385/18639 0.0025974025974026 0.158731104960613 0.998369683905422 0.999666860252109 GO:0140098 catalytic activity, acting on RNA 1/305 387/18639 0.00258397932816537 0.157910789172703 0.998423711038103 0.999666860252109 GO:0016887 ATP hydrolysis activity 1/305 417/18639 0.00239808153477218 0.146550300743012 0.99904961007833 0.999666860252109 GO:0004842 ubiquitin-protein transferase activity 1/305 449/18639 0.0022271714922049 0.136105735879368 0.999446501565333 0.999666860252109 GO:0046873 metal ion transmembrane transporter activity 1/305 450/18639 0.00222222222222222 0.135803278688525 0.999455782325232 0.999666860252109 GO:0019787 ubiquitin-like protein transferase activity 1/305 479/18639 0.00208768267223382 0.127581368287758 0.999666860252109 0.999666860252109