ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0015453 oxidoreduction-driven active transmembrane transporter activity 10/71 68/18639 0.147058823529412 38.606048053024 8.11631043387136e-14 2.41866050929367e-11 GO:0009055 electron transfer activity 11/71 116/18639 0.0948275862068965 24.8942447790189 6.25951056390807e-13 9.32667074022303e-11 GO:0015399 primary active transmembrane transporter activity 12/71 166/18639 0.072289156626506 18.9774308501612 1.35503126535585e-12 1.34599772358681e-10 GO:0015078 proton transmembrane transporter activity 12/71 185/18639 0.0648648648648649 17.028397411496 4.90882108607175e-12 3.65707170912346e-10 GO:0022853 active monoatomic ion transmembrane transporter activity 10/71 118/18639 0.0847457627118644 22.247553115302 2.34301889912255e-11 1.39643926387704e-09 GO:0008137 NADH dehydrogenase (ubiquinone) activity 7/71 41/18639 0.170731707317073 44.8206801786328 1.74246661097386e-10 8.65425083450351e-09 GO:0003954 NADH dehydrogenase activity 7/71 44/18639 0.159090909090909 41.7647247119078 2.94334315239341e-10 1.25302322773319e-08 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 7/71 58/18639 0.120689655172414 31.6835842642059 2.21413363324293e-09 8.24764778382993e-08 GO:0022804 active transmembrane transporter activity 13/71 457/18639 0.0284463894967177 7.46777822294819 1.55593836626044e-08 5.15188481272901e-07 GO:0016651 oxidoreductase activity, acting on NAD(P)H 7/71 88/18639 0.0795454545454545 20.8823623559539 4.271228815951e-08 1.2728261871534e-06 GO:0005201 extracellular matrix structural constituent 6/71 168/18639 0.0357142857142857 9.37575452716298 4.32599364710263e-05 0.00117195100621508 GO:0005539 glycosaminoglycan binding 6/71 242/18639 0.0247933884297521 6.50878826679083 0.000318679939792446 0.0079138851715124 GO:0008201 heparin binding 5/71 172/18639 0.0290697674418605 7.63142810350475 0.000502649172858778 0.0115222656547627 GO:1901681 sulfur compound binding 6/71 275/18639 0.0218181818181818 5.72773367477593 0.000626691299006937 0.0133395719360048 GO:0140333 glycerophospholipid flippase activity 2/71 13/18639 0.153846153846154 40.3878656554713 0.00108602349012981 0.021575666670579 GO:0170055 lipid transmembrane transporter activity 3/71 56/18639 0.0535714285714286 14.0636317907445 0.00127045029156566 0.0236621366804104 GO:0004129 cytochrome-c oxidase activity 2/71 15/18639 0.133333333333333 35.0028169014085 0.00145476915571851 0.0255012475531834 GO:0016675 oxidoreductase activity, acting on a heme group of donors 2/71 16/18639 0.125 32.8151408450704 0.00165850411620746 0.0260123277173591 GO:0140327 flippase activity 2/71 16/18639 0.125 32.8151408450704 0.00165850411620746 0.0260123277173591 GO:0048038 quinone binding 2/71 17/18639 0.117647058823529 30.8848384424192 0.00187501622600211 0.0279377417674315 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 2/71 18/18639 0.111111111111111 29.169014084507 0.00210420796138682 0.0298597129758702 GO:0030021 extracellular matrix structural constituent conferring compression resistance 2/71 22/18639 0.0909090909090909 23.865556978233 0.00314583950847508 0.0426118260693442 GO:0015252 proton channel activity 2/71 27/18639 0.0740740740740741 19.4460093896714 0.00472169026530025 0.0586276541274781 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 2/71 27/18639 0.0740740740740741 19.4460093896714 0.00472169026530025 0.0586276541274781 GO:0001968 fibronectin binding 2/71 30/18639 0.0666666666666667 17.5014084507042 0.00580874945949024 0.0692402935571237 GO:0140303 intramembrane lipid transporter activity 2/71 45/18639 0.0444444444444444 11.6676056338028 0.0127433497008105 0.146058392724675 GO:0140359 ABC-type transporter activity 2/71 47/18639 0.0425531914893617 11.1711117770453 0.0138469192968126 0.152828961127783 GO:0019838 growth factor binding 3/71 136/18639 0.0220588235294118 5.7909072079536 0.0151383512108493 0.161115309315467 GO:1901505 carbohydrate derivative transmembrane transporter activity 2/71 53/18639 0.0377358490566038 9.90645761360616 0.0173948644040279 0.178747227324149 GO:0016504 peptidase activator activity 2/71 57/18639 0.0350877192982456 9.2112676056338 0.0199514115768488 0.198184021663365 GO:0016887 ATP hydrolysis activity 5/71 417/18639 0.0119904076738609 3.14773533286047 0.0213458301516933 0.20519539952273 GO:0005178 integrin binding 3/71 161/18639 0.0186335403726708 4.89169801417199 0.0235690569106712 0.217273976084395 GO:0005507 copper ion binding 2/71 63/18639 0.0317460317460317 8.33400402414487 0.0240605409757887 0.217273976084395 GO:0016874 ligase activity 3/71 167/18639 0.0179640718562874 4.7159483849203 0.0259024774258756 0.227027596262086 GO:0016500 protein-hormone receptor activity 2/71 67/18639 0.0298507462686567 7.83645154509145 0.0269757090220081 0.229507885559576 GO:0005548 phospholipid transporter activity 2/71 68/18639 0.0294117647058824 7.72120961060481 0.0277257848327004 0.229507885559576 GO:0008028 monocarboxylic acid transmembrane transporter activity 2/71 70/18639 0.0285714285714286 7.50060362173038 0.0292509638180734 0.235412589528488 GO:0005319 lipid transporter activity 3/71 178/18639 0.0168539325842697 4.42451337236905 0.030491959120524 0.235412589528488 GO:0042379 chemokine receptor binding 2/71 72/18639 0.0277777777777778 7.29225352112676 0.0308090301731913 0.235412589528488 GO:0004955 prostaglandin receptor activity 1/71 10/18639 0.1 26.2521126760563 0.037454693894947 0.272231677577908 GO:0043225 ATPase-coupled inorganic anion transmembrane transporter activity 1/71 10/18639 0.1 26.2521126760563 0.037454693894947 0.272231677577908 GO:0004954 prostanoid receptor activity 1/71 11/18639 0.0909090909090909 23.865556978233 0.0411232062538206 0.284993382875315 GO:0031731 CCR6 chemokine receptor binding 1/71 11/18639 0.0909090909090909 23.865556978233 0.0411232062538206 0.284993382875315 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 2/71 86/18639 0.0232558139534884 6.1051424828038 0.0425890225106919 0.288443834276959 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 1/71 13/18639 0.0769230769230769 20.1939328277356 0.0484189256061832 0.290993918802959 GO:0031994 insulin-like growth factor I binding 1/71 13/18639 0.0769230769230769 20.1939328277356 0.0484189256061832 0.290993918802959 GO:0045159 myosin II binding 1/71 13/18639 0.0769230769230769 20.1939328277356 0.0484189256061832 0.290993918802959 GO:0046974 histone H3K9 methyltransferase activity 1/71 13/18639 0.0769230769230769 20.1939328277356 0.0484189256061832 0.290993918802959 GO:0071714 icosanoid transmembrane transporter activity 1/71 13/18639 0.0769230769230769 20.1939328277356 0.0484189256061832 0.290993918802959 GO:0005161 platelet-derived growth factor receptor binding 1/71 14/18639 0.0714285714285714 18.751509054326 0.0520462345443327 0.290993918802959 GO:0005545 1-phosphatidylinositol binding 1/71 14/18639 0.0714285714285714 18.751509054326 0.0520462345443327 0.290993918802959 GO:0008559 ABC-type xenobiotic transporter activity 1/71 14/18639 0.0714285714285714 18.751509054326 0.0520462345443327 0.290993918802959 GO:0044548 S100 protein binding 1/71 14/18639 0.0714285714285714 18.751509054326 0.0520462345443327 0.290993918802959 GO:0042626 ATPase-coupled transmembrane transporter activity 2/71 98/18639 0.0204081632653061 5.3575740155217 0.0538046895784999 0.290993918802959 GO:0061134 peptidase regulator activity 3/71 226/18639 0.0132743362831858 3.48479371806058 0.0551379807093717 0.290993918802959 GO:0004953 icosanoid receptor activity 1/71 15/18639 0.0666666666666667 17.5014084507042 0.0556599106435191 0.290993918802959 GO:0045504 dynein heavy chain binding 1/71 15/18639 0.0666666666666667 17.5014084507042 0.0556599106435191 0.290993918802959 GO:0005324 long-chain fatty acid transmembrane transporter activity 1/71 16/18639 0.0625 16.4075704225352 0.0592600044120066 0.299313242623356 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 1/71 16/18639 0.0625 16.4075704225352 0.0592600044120066 0.299313242623356 GO:0070403 NAD+ binding 1/71 17/18639 0.0588235294117647 15.4424192212096 0.062846566173632 0.312137945329039 GO:1902936 phosphatidylinositol bisphosphate binding 2/71 111/18639 0.018018018018018 4.73011039208222 0.06698597529913 0.325841087936582 GO:0005520 insulin-like growth factor binding 1/71 19/18639 0.0526315789473684 13.8169014084507 0.069979294053494 0.325841087936582 GO:0015245 fatty acid transmembrane transporter activity 1/71 19/18639 0.0526315789473684 13.8169014084507 0.069979294053494 0.325841087936582 GO:0016918 retinal binding 1/71 19/18639 0.0526315789473684 13.8169014084507 0.069979294053494 0.325841087936582 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 1/71 20/18639 0.05 13.1260563380282 0.0735255599032364 0.337086413094838 GO:0015125 bile acid transmembrane transporter activity 1/71 21/18639 0.0476190476190476 12.5010060362173 0.0770584932104427 0.340841046961709 GO:0072542 protein phosphatase activator activity 1/71 21/18639 0.0476190476190476 12.5010060362173 0.0770584932104427 0.340841046961709 GO:0051082 unfolded protein binding 2/71 121/18639 0.0165289256198347 4.33919217786055 0.0777758093738127 0.340841046961709 GO:0031681 G-protein beta-subunit binding 1/71 23/18639 0.0434782608695652 11.413962033068 0.0840845596632236 0.361133572103931 GO:0005540 hyaluronic acid binding 1/71 24/18639 0.0416666666666667 10.9383802816901 0.0875777910912379 0.361133572103931 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 1/71 24/18639 0.0416666666666667 10.9383802816901 0.0875777910912379 0.361133572103931 GO:0048027 mRNA 5'-UTR binding 1/71 24/18639 0.0416666666666667 10.9383802816901 0.0875777910912379 0.361133572103931 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 1/71 25/18639 0.04 10.5008450704225 0.0910578865428905 0.361133572103931 GO:0019211 phosphatase activator activity 1/71 25/18639 0.04 10.5008450704225 0.0910578865428905 0.361133572103931 GO:0030246 carbohydrate binding 3/71 280/18639 0.0107142857142857 2.81272635814889 0.0912013485544471 0.361133572103931 GO:0035091 phosphatidylinositol binding 3/71 284/18639 0.0105633802816901 2.77311049394961 0.0941892260243444 0.361133572103931 GO:0043548 phosphatidylinositol 3-kinase binding 1/71 26/18639 0.0384615384615385 10.0969664138678 0.0945248947117671 0.361133572103931 GO:0070006 metalloaminopeptidase activity 1/71 26/18639 0.0384615384615385 10.0969664138678 0.0945248947117671 0.361133572103931 GO:0035255 ionotropic glutamate receptor binding 1/71 27/18639 0.037037037037037 9.72300469483568 0.0979788641135537 0.36959115830176 GO:0020037 heme binding 2/71 142/18639 0.0140845070422535 3.69748065859948 0.102016037573557 0.376441785280822 GO:0001664 G protein-coupled receptor binding 3/71 297/18639 0.0101010101010101 2.651728553137 0.104175175127438 0.376441785280822 GO:0004629 phospholipase C activity 1/71 29/18639 0.0344827586206897 9.05245264691598 0.10484787979298 0.376441785280822 GO:0051861 glycolipid binding 1/71 29/18639 0.0344827586206897 9.05245264691598 0.10484787979298 0.376441785280822 GO:0019842 vitamin binding 2/71 150/18639 0.0133333333333333 3.50028169014085 0.111738365587696 0.396405154108731 GO:0046906 tetrapyrrole binding 2/71 152/18639 0.0131578947368421 3.45422535211268 0.114206145323831 0.398678313457465 GO:0042910 xenobiotic transmembrane transporter activity 1/71 32/18639 0.03125 8.20378521126761 0.115054815293094 0.398678313457465 GO:0030296 protein tyrosine kinase activator activity 1/71 33/18639 0.0303030303030303 7.95518565941101 0.118431561040081 0.399791423711553 GO:0140416 transcription regulator inhibitor activity 1/71 33/18639 0.0303030303030303 7.95518565941101 0.118431561040081 0.399791423711553 GO:0090482 vitamin transmembrane transporter activity 1/71 34/18639 0.0294117647058824 7.72120961060481 0.121795602702241 0.399791423711553 GO:0015103 inorganic anion transmembrane transporter activity 2/71 165/18639 0.0121212121212121 3.1820742637644 0.130576520493836 0.399791423711553 GO:0043394 proteoglycan binding 1/71 37/18639 0.027027027027027 7.09516558812333 0.131811973473229 0.399791423711553 GO:0005501 retinoid binding 1/71 38/18639 0.0263157894736842 6.90845070422535 0.135125668230965 0.399791423711553 GO:0019840 isoprenoid binding 1/71 38/18639 0.0263157894736842 6.90845070422535 0.135125668230965 0.399791423711553 GO:0043531 ADP binding 1/71 38/18639 0.0263157894736842 6.90845070422535 0.135125668230965 0.399791423711553 GO:0004177 aminopeptidase activity 1/71 40/18639 0.025 6.56302816901408 0.141715693335522 0.399791423711553 GO:0071855 neuropeptide receptor binding 1/71 40/18639 0.025 6.56302816901408 0.141715693335522 0.399791423711553 GO:0140662 ATP-dependent protein folding chaperone 1/71 40/18639 0.025 6.56302816901408 0.141715693335522 0.399791423711553 GO:0035198 miRNA binding 1/71 42/18639 0.0238095238095238 6.25050301810865 0.148256206783852 0.399791423711553 GO:0048487 beta-tubulin binding 1/71 42/18639 0.0238095238095238 6.25050301810865 0.148256206783852 0.399791423711553 GO:0051879 Hsp90 protein binding 1/71 42/18639 0.0238095238095238 6.25050301810865 0.148256206783852 0.399791423711553 GO:0043014 alpha-tubulin binding 1/71 44/18639 0.0227272727272727 5.96638924455826 0.1547475752883 0.399791423711553 GO:0008237 metallopeptidase activity 2/71 184/18639 0.0108695652173913 2.85349050826699 0.155388914585266 0.399791423711553 GO:1901981 phosphatidylinositol phosphate binding 2/71 185/18639 0.0108108108108108 2.83806623524933 0.156719706332221 0.399791423711553 GO:0008009 chemokine activity 1/71 45/18639 0.0222222222222222 5.83380281690141 0.157974944051651 0.399791423711553 GO:0046943 carboxylic acid transmembrane transporter activity 2/71 188/18639 0.0106382978723404 2.79277794426131 0.160725317535379 0.399791423711553 GO:0030291 protein serine/threonine kinase inhibitor activity 1/71 46/18639 0.0217391304347826 5.70698101653399 0.161190162884196 0.399791423711553 GO:0005342 organic acid transmembrane transporter activity 2/71 189/18639 0.0105820105820106 2.77800134138162 0.162064815527182 0.399791423711553 GO:0140938 histone H3 methyltransferase activity 1/71 47/18639 0.0212765957446809 5.58555588852263 0.164393276875226 0.399791423711553 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 1/71 48/18639 0.0208333333333333 5.46919014084507 0.167584330949121 0.399791423711553 GO:0038187 pattern recognition receptor activity 1/71 48/18639 0.0208333333333333 5.46919014084507 0.167584330949121 0.399791423711553 GO:0005004 GPI-linked ephrin receptor activity 1/71 49/18639 0.0204081632653061 5.3575740155217 0.170763369865941 0.399791423711553 GO:0005008 hepatocyte growth factor receptor activity 1/71 49/18639 0.0204081632653061 5.3575740155217 0.170763369865941 0.399791423711553 GO:0005009 insulin receptor activity 1/71 49/18639 0.0204081632653061 5.3575740155217 0.170763369865941 0.399791423711553 GO:0005011 macrophage colony-stimulating factor receptor activity 1/71 49/18639 0.0204081632653061 5.3575740155217 0.170763369865941 0.399791423711553 GO:0005018 platelet-derived growth factor alpha-receptor activity 1/71 49/18639 0.0204081632653061 5.3575740155217 0.170763369865941 0.399791423711553 GO:0005020 stem cell factor receptor activity 1/71 49/18639 0.0204081632653061 5.3575740155217 0.170763369865941 0.399791423711553 GO:0008288 boss receptor activity 1/71 49/18639 0.0204081632653061 5.3575740155217 0.170763369865941 0.399791423711553 GO:0035254 glutamate receptor binding 1/71 49/18639 0.0204081632653061 5.3575740155217 0.170763369865941 0.399791423711553 GO:0036332 placental growth factor receptor activity 1/71 49/18639 0.0204081632653061 5.3575740155217 0.170763369865941 0.399791423711553 GO:0038062 protein tyrosine kinase collagen receptor activity 1/71 49/18639 0.0204081632653061 5.3575740155217 0.170763369865941 0.399791423711553 GO:0060175 brain-derived neurotrophic factor receptor activity 1/71 49/18639 0.0204081632653061 5.3575740155217 0.170763369865941 0.399791423711553 GO:0005006 epidermal growth factor receptor activity 1/71 50/18639 0.02 5.25042253521127 0.173930438222022 0.399791423711553 GO:0005007 fibroblast growth factor receptor activity 1/71 50/18639 0.02 5.25042253521127 0.173930438222022 0.399791423711553 GO:0005017 platelet-derived growth factor receptor activity 1/71 50/18639 0.02 5.25042253521127 0.173930438222022 0.399791423711553 GO:0005019 platelet-derived growth factor beta-receptor activity 1/71 50/18639 0.02 5.25042253521127 0.173930438222022 0.399791423711553 GO:0015605 organophosphate ester transmembrane transporter activity 1/71 50/18639 0.02 5.25042253521127 0.173930438222022 0.399791423711553 GO:0048020 CCR chemokine receptor binding 1/71 50/18639 0.02 5.25042253521127 0.173930438222022 0.399791423711553 GO:0005010 insulin-like growth factor receptor activity 1/71 51/18639 0.0196078431372549 5.14747307373654 0.177085580450556 0.399791423711553 GO:0005021 vascular endothelial growth factor receptor activity 1/71 51/18639 0.0196078431372549 5.14747307373654 0.177085580450556 0.399791423711553 GO:0005030 neurotrophin receptor activity 1/71 51/18639 0.0196078431372549 5.14747307373654 0.177085580450556 0.399791423711553 GO:0030544 Hsp70 protein binding 1/71 51/18639 0.0196078431372549 5.14747307373654 0.177085580450556 0.399791423711553 GO:0030159 signaling receptor complex adaptor activity 1/71 52/18639 0.0192307692307692 5.04848320693391 0.180228840822195 0.399791423711553 GO:0015631 tubulin binding 3/71 385/18639 0.00779220779220779 2.04561916956283 0.181139772432757 0.399791423711553 GO:0005003 ephrin receptor activity 1/71 53/18639 0.0188679245283019 4.95322880680308 0.183360263445621 0.399791423711553 GO:0005005 transmembrane-ephrin receptor activity 1/71 53/18639 0.0188679245283019 4.95322880680308 0.183360263445621 0.399791423711553 GO:0038064 collagen receptor activity 1/71 53/18639 0.0188679245283019 4.95322880680308 0.183360263445621 0.399791423711553 GO:0017069 snRNA binding 1/71 54/18639 0.0185185185185185 4.86150234741784 0.186479892268141 0.399791423711553 GO:0051287 NAD binding 1/71 54/18639 0.0185185185185185 4.86150234741784 0.186479892268141 0.399791423711553 GO:0140463 chromatin-protein adaptor activity 1/71 54/18639 0.0185185185185185 4.86150234741784 0.186479892268141 0.399791423711553 GO:0051015 actin filament binding 2/71 209/18639 0.00956937799043062 2.51216389244558 0.189248702834708 0.402829381748164 GO:0061980 regulatory RNA binding 1/71 58/18639 0.0172413793103448 4.52622632345799 0.198841342879535 0.420246242397882 GO:0001786 phosphatidylserine binding 1/71 59/18639 0.0169491525423729 4.4495106230604 0.201902656299455 0.423711208290406 GO:0004714 transmembrane receptor protein tyrosine kinase activity 1/71 60/18639 0.0166666666666667 4.37535211267606 0.204952436245782 0.42710367833037 GO:1901682 sulfur compound transmembrane transporter activity 1/71 63/18639 0.0158730158730159 4.16700201207243 0.214033002798118 0.442929408568327 GO:0008235 metalloexopeptidase activity 1/71 66/18639 0.0151515151515152 3.97759282970551 0.223011300729427 0.458326673223237 GO:0042054 histone methyltransferase activity 1/71 67/18639 0.0149253731343284 3.91822577254572 0.225981536967419 0.460974947683302 GO:0003777 microtubule motor activity 1/71 68/18639 0.0147058823529412 3.8606048053024 0.228940578044056 0.460974947683302 GO:1990841 promoter-specific chromatin binding 1/71 68/18639 0.0147058823529412 3.8606048053024 0.228940578044056 0.460974947683302 GO:0016279 protein-lysine N-methyltransferase activity 1/71 69/18639 0.0144927536231884 3.80465401102266 0.23188846555463 0.463429945700336 GO:0016278 lysine N-methyltransferase activity 1/71 70/18639 0.0142857142857143 3.75030181086519 0.234825240942117 0.463429945700336 GO:0097110 scaffold protein binding 1/71 70/18639 0.0142857142857143 3.75030181086519 0.234825240942117 0.463429945700336 GO:0003779 actin binding 3/71 443/18639 0.00677200902934537 1.77779544081646 0.238294234072493 0.465279829126536 GO:0005518 collagen binding 1/71 72/18639 0.0138888888888889 3.64612676056338 0.240665620361452 0.465279829126536 GO:0033218 amide binding 2/71 247/18639 0.00809716599190283 2.12567713976165 0.242301267038601 0.465279829126536 GO:0005216 monoatomic ion channel activity 3/71 448/18639 0.00669642857142857 1.75795397384306 0.243374664248859 0.465279829126536 GO:0004521 RNA endonuclease activity 1/71 73/18639 0.0136986301369863 3.59617981863785 0.243569306522616 0.465279829126536 GO:0044183 protein folding chaperone 1/71 75/18639 0.0133333333333333 3.50028169014085 0.24934387594445 0.470953668559815 GO:0017022 myosin binding 1/71 76/18639 0.0131578947368421 3.45422535211268 0.25221484043529 0.470953668559815 GO:0019887 protein kinase regulator activity 2/71 255/18639 0.00784313725490196 2.05898922949461 0.253593795019311 0.470953668559815 GO:0003713 transcription coactivator activity 2/71 256/18639 0.0078125 2.0509463028169 0.255006670154774 0.470953668559815 GO:0003724 RNA helicase activity 1/71 77/18639 0.012987012987013 3.40936528260472 0.255074978684985 0.470953668559815 GO:0019199 transmembrane receptor protein kinase activity 1/71 78/18639 0.0128205128205128 3.36565547128927 0.257924330937617 0.470953668559815 GO:0008186 ATP-dependent activity, acting on RNA 1/71 79/18639 0.0126582278481013 3.32305223747549 0.260762937289831 0.470953668559815 GO:0015370 solute:sodium symporter activity 1/71 79/18639 0.0126582278481013 3.32305223747549 0.260762937289831 0.470953668559815 GO:0033293 monocarboxylic acid binding 1/71 79/18639 0.0126582278481013 3.32305223747549 0.260762937289831 0.470953668559815 GO:0048306 calcium-dependent protein binding 1/71 80/18639 0.0125 3.28151408450704 0.263590837691362 0.473193190554373 GO:0001540 amyloid-beta binding 1/71 83/18639 0.0120481927710843 3.16290514169353 0.272010700496778 0.478884559968786 GO:0005254 chloride channel activity 1/71 83/18639 0.0120481927710843 3.16290514169353 0.272010700496778 0.478884559968786 GO:0008514 organic anion transmembrane transporter activity 2/71 269/18639 0.00743494423791822 1.95182993874025 0.273385981154418 0.478884559968786 GO:0004860 protein kinase inhibitor activity 1/71 84/18639 0.0119047619047619 3.12525150905433 0.274796173673364 0.478884559968786 GO:0051117 ATPase binding 1/71 84/18639 0.0119047619047619 3.12525150905433 0.274796173673364 0.478884559968786 GO:0016209 antioxidant activity 1/71 86/18639 0.0116279069767442 3.0525712414019 0.280335633944655 0.482061316104874 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 3/71 484/18639 0.00619834710743802 1.62719706669771 0.280428060429203 0.482061316104874 GO:0005126 cytokine receptor binding 2/71 275/18639 0.00727272727272727 1.90924455825864 0.281868349992839 0.482061316104874 GO:0008081 phosphoric diester hydrolase activity 1/71 87/18639 0.0114942528735632 3.01748421563866 0.283089699054876 0.482061316104874 GO:0001216 DNA-binding transcription activator activity 3/71 491/18639 0.00610997963340122 1.60399873784458 0.287706957765329 0.487140189852659 GO:0019210 kinase inhibitor activity 1/71 90/18639 0.0111111111111111 2.9169014084507 0.291289699379896 0.489456558640012 GO:0005543 phospholipid binding 3/71 497/18639 0.00603621730382294 1.58463456797121 0.293959433231458 0.489456558640012 GO:0072341 modified amino acid binding 1/71 91/18639 0.010989010989011 2.88484754681938 0.294002429518665 0.489456558640012 GO:0052689 carboxylic ester hydrolase activity 1/71 92/18639 0.0108695652173913 2.85349050826699 0.296704921836121 0.490221812621443 GO:0019207 kinase regulator activity 2/71 287/18639 0.00696864111498258 1.82941551749522 0.29881057876431 0.490221812621443 GO:0051213 dioxygenase activity 1/71 93/18639 0.010752688172043 2.82280781462971 0.299397214419808 0.490221812621443 GO:0004867 serine-type endopeptidase inhibitor activity 1/71 95/18639 0.0105263157894737 2.76338028169014 0.3047513520383 0.493564689714204 GO:0008276 protein methyltransferase activity 1/71 95/18639 0.0105263157894737 2.76338028169014 0.3047513520383 0.493564689714204 GO:0008170 N-methyltransferase activity 1/71 98/18639 0.0102040816326531 2.67878700776085 0.312707004648412 0.503711823703928 GO:0008238 exopeptidase activity 1/71 102/18639 0.00980392156862745 2.57373653686827 0.323175075369129 0.51777512075269 GO:0005253 monoatomic anion channel activity 1/71 103/18639 0.00970873786407767 2.54874880350062 0.325767434955296 0.519137409714857 GO:0008013 beta-catenin binding 1/71 106/18639 0.00943396226415094 2.47661440340154 0.333485920093131 0.528610660573155 GO:0019888 protein phosphatase regulator activity 1/71 107/18639 0.00934579439252336 2.45346847439779 0.336039338302455 0.529839803249373 GO:0004843 cysteine-type deubiquitinase activity 1/71 108/18639 0.00925925925925926 2.43075117370892 0.338583111612433 0.531040880318448 GO:0004620 phospholipase activity 1/71 109/18639 0.00917431192660551 2.40845070422535 0.341117275935758 0.532214388632753 GO:0004222 metalloendopeptidase activity 1/71 110/18639 0.00909090909090909 2.3865556978233 0.343641867053327 0.533360814489018 GO:0035401 histone H3Y41 kinase activity 1/71 115/18639 0.00869565217391304 2.28279240661359 0.356122467720984 0.544228181440272 GO:0101005 deubiquitinase activity 1/71 115/18639 0.00869565217391304 2.28279240661359 0.356122467720984 0.544228181440272 GO:0140801 histone H2AXY142 kinase activity 1/71 115/18639 0.00869565217391304 2.28279240661359 0.356122467720984 0.544228181440272 GO:0015294 solute:monoatomic cation symporter activity 1/71 116/18639 0.00862068965517241 2.26311316172899 0.358590363682536 0.545203716211203 GO:0019208 phosphatase regulator activity 1/71 117/18639 0.00854700854700855 2.24377031419285 0.361048933254341 0.546155239136009 GO:0004540 RNA nuclease activity 1/71 121/18639 0.00826446280991736 2.16959608893028 0.370790640605351 0.554440436969283 GO:0015108 chloride transmembrane transporter activity 1/71 121/18639 0.00826446280991736 2.16959608893028 0.370790640605351 0.554440436969283 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/71 122/18639 0.00819672131147541 2.15181251443085 0.373203096838045 0.554440436969283 GO:0005261 monoatomic cation channel activity 2/71 341/18639 0.00586510263929619 1.53971335343439 0.373968214197402 0.554440436969283 GO:0004519 endonuclease activity 1/71 127/18639 0.0078740157480315 2.06709548630365 0.385129258348527 0.565362162501779 GO:0019783 ubiquitin-like protein peptidase activity 1/71 127/18639 0.0078740157480315 2.06709548630365 0.385129258348527 0.565362162501779 GO:0035591 signaling adaptor activity 1/71 129/18639 0.00775193798449612 2.03504749426793 0.389836829614729 0.565817355091109 GO:0141003 histone H2AX kinase activity 2/71 354/18639 0.00564971751412429 1.4831702076868 0.391636192068028 0.565817355091109 GO:0016298 lipase activity 1/71 130/18639 0.00769230769230769 2.01939328277356 0.392177271813398 0.565817355091109 GO:0031072 heat shock protein binding 1/71 131/18639 0.00763358778625954 2.00397806687453 0.394508862590925 0.565817355091109 GO:0140996 histone H3 kinase activity 2/71 357/18639 0.00560224089635854 1.47070659249615 0.395683369427542 0.565817355091109 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 1/71 132/18639 0.00757575757575758 1.98879641485275 0.396831634946449 0.565817355091109 GO:0035173 histone kinase activity 2/71 360/18639 0.00555555555555556 1.45845070422535 0.399718710850166 0.566977985891507 GO:0051087 protein-folding chaperone binding 1/71 134/18639 0.00746268656716418 1.95911288627286 0.401450855782242 0.566977985891507 GO:0002020 protease binding 1/71 136/18639 0.00735294117647059 1.9303024026512 0.406035195896811 0.57074758668514 GO:0046982 protein heterodimerization activity 2/71 369/18639 0.00542005420054201 1.42287873582961 0.411751200823148 0.572224967042166 GO:0030295 protein kinase activator activity 1/71 139/18639 0.00719424460431655 1.88864119971628 0.412846872194851 0.572224967042166 GO:0070851 growth factor receptor binding 1/71 139/18639 0.00719424460431655 1.88864119971628 0.412846872194851 0.572224967042166 GO:0004713 protein tyrosine kinase activity 1/71 140/18639 0.00714285714285714 1.8751509054326 0.415100270685347 0.572684632704784 GO:0015293 symporter activity 1/71 146/18639 0.00684931506849315 1.79808990931893 0.428442707257415 0.579832154385909 GO:0019209 kinase activator activity 1/71 148/18639 0.00675675675675676 1.77379139703083 0.432823149643573 0.579832154385909 GO:0008509 monoatomic anion transmembrane transporter activity 1/71 149/18639 0.00671140939597315 1.7618867567823 0.435000941887114 0.579832154385909 GO:0140098 catalytic activity, acting on RNA 2/71 387/18639 0.00516795865633075 1.35669832951196 0.435464326684941 0.579832154385909 GO:0000510 H3-H4 histone complex chaperone activity 1/71 151/18639 0.00662251655629139 1.7385505083481 0.43933182288839 0.579832154385909 GO:0140584 chromatin extrusion motor activity 1/71 151/18639 0.00662251655629139 1.7385505083481 0.43933182288839 0.579832154385909 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 1/71 151/18639 0.00662251655629139 1.7385505083481 0.43933182288839 0.579832154385909 GO:0140849 ATP-dependent H2AZ histone chaperone activity 1/71 151/18639 0.00662251655629139 1.7385505083481 0.43933182288839 0.579832154385909 GO:0015616 DNA translocase activity 1/71 152/18639 0.00657894736842105 1.72711267605634 0.441484973070937 0.579832154385909 GO:0140674 ATP-dependent histone chaperone activity 1/71 152/18639 0.00657894736842105 1.72711267605634 0.441484973070937 0.579832154385909 GO:0003774 cytoskeletal motor activity 1/71 153/18639 0.0065359477124183 1.71582435791218 0.443629970469756 0.579832154385909 GO:0061775 cohesin loader activity 1/71 153/18639 0.0065359477124183 1.71582435791218 0.443629970469756 0.579832154385909 GO:0004386 helicase activity 1/71 155/18639 0.00645161290322581 1.69368468877783 0.4478956285271 0.582851079917361 GO:0140658 ATP-dependent chromatin remodeler activity 1/71 158/18639 0.00632911392405063 1.66152611873774 0.454233726873193 0.588528915687877 GO:0003689 DNA clamp loader activity 1/71 160/18639 0.00625 1.64075704225352 0.458419216442658 0.588965764643726 GO:0004175 endopeptidase activity 2/71 405/18639 0.00493827160493827 1.29640062597809 0.458671120311146 0.588965764643726 GO:0004866 endopeptidase inhibitor activity 1/71 161/18639 0.0062111801242236 1.630566004724 0.460500077724793 0.588965764643726 GO:0015081 sodium ion transmembrane transporter activity 1/71 164/18639 0.00609756097560976 1.60073857780831 0.466695481793009 0.591809589677943 GO:0140713 histone chaperone activity 1/71 164/18639 0.00609756097560976 1.60073857780831 0.466695481793009 0.591809589677943 GO:0004857 enzyme inhibitor activity 2/71 416/18639 0.00480769230769231 1.26212080173348 0.472587297106655 0.594517206043614 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 1/71 167/18639 0.00598802395209581 1.57198279497343 0.472820730980995 0.594517206043614 GO:0030414 peptidase inhibitor activity 1/71 169/18639 0.00591715976331361 1.55337944828736 0.476865642622701 0.597083871855315 GO:0004252 serine-type endopeptidase activity 1/71 176/18639 0.00568181818181818 1.49159731113956 0.490783338173737 0.61193905763922 GO:0061135 endopeptidase regulator activity 1/71 184/18639 0.00543478260869565 1.4267452541335 0.506242653014408 0.62858462749289 GO:0008234 cysteine-type peptidase activity 1/71 187/18639 0.0053475935828877 1.40385629283724 0.511919807090133 0.629488625711978 GO:0031406 carboxylic acid binding 1/71 187/18639 0.0053475935828877 1.40385629283724 0.511919807090133 0.629488625711978 GO:0140597 protein carrier chaperone 1/71 188/18639 0.00531914893617021 1.39638897213066 0.513797852488821 0.629488625711978 GO:0043177 organic acid binding 1/71 189/18639 0.00529100529100529 1.38900067069081 0.515668772898192 0.629488625711978 GO:0019902 phosphatase binding 1/71 190/18639 0.00526315789473684 1.38169014084507 0.517532594964546 0.629488625711978 GO:0008236 serine-type peptidase activity 1/71 194/18639 0.00515463917525773 1.3532016843328 0.52491742929582 0.635875585081929 GO:0017171 serine hydrolase activity 1/71 198/18639 0.00505050505050505 1.3258642765685 0.532190796456575 0.642076345522507 GO:0008168 methyltransferase activity 1/71 204/18639 0.00490196078431373 1.28686826843413 0.54289546824802 0.652350199749637 GO:0004518 nuclease activity 1/71 209/18639 0.00478468899521531 1.25608194622279 0.551631259497131 0.657779430881764 GO:0008094 ATP-dependent activity, acting on DNA 1/71 210/18639 0.00476190476190476 1.25010060362173 0.553358561753002 0.657779430881764 GO:0016741 transferase activity, transferring one-carbon groups 1/71 215/18639 0.00465116279069767 1.22102849656076 0.56189714922563 0.657779430881764 GO:0003712 transcription coregulator activity 2/71 495/18639 0.00404040404040404 1.0606914212548 0.566020529760495 0.657779430881764 GO:0000287 magnesium ion binding 1/71 230/18639 0.00434782608695652 1.1413962033068 0.586558951024852 0.657779430881764 GO:0005125 cytokine activity 1/71 234/18639 0.00427350427350427 1.12188515709642 0.592900912954928 0.657779430881764 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 1/71 243/18639 0.00411522633744856 1.08033385498174 0.606821750455427 0.657779430881764 GO:0004676 3-phosphoinositide-dependent protein kinase activity 1/71 245/18639 0.00408163265306122 1.07151480310434 0.609850946025356 0.657779430881764 GO:0004711 ribosomal protein S6 kinase activity 1/71 245/18639 0.00408163265306122 1.07151480310434 0.609850946025356 0.657779430881764 GO:0035175 histone H3S10 kinase activity 1/71 245/18639 0.00408163265306122 1.07151480310434 0.609850946025356 0.657779430881764 GO:0035979 histone H2AXS139 kinase activity 1/71 245/18639 0.00408163265306122 1.07151480310434 0.609850946025356 0.657779430881764 GO:0044022 histone H3S28 kinase activity 1/71 245/18639 0.00408163265306122 1.07151480310434 0.609850946025356 0.657779430881764 GO:0044023 histone H4S1 kinase activity 1/71 245/18639 0.00408163265306122 1.07151480310434 0.609850946025356 0.657779430881764 GO:0044024 histone H2AS1 kinase activity 1/71 245/18639 0.00408163265306122 1.07151480310434 0.609850946025356 0.657779430881764 GO:0044025 histone H2BS14 kinase activity 1/71 245/18639 0.00408163265306122 1.07151480310434 0.609850946025356 0.657779430881764 GO:0072354 histone H3T3 kinase activity 1/71 245/18639 0.00408163265306122 1.07151480310434 0.609850946025356 0.657779430881764 GO:0072371 histone H2AS121 kinase activity 1/71 245/18639 0.00408163265306122 1.07151480310434 0.609850946025356 0.657779430881764 GO:0072518 Rho-dependent protein serine/threonine kinase activity 1/71 245/18639 0.00408163265306122 1.07151480310434 0.609850946025356 0.657779430881764 GO:0140823 histone H2BS36 kinase activity 1/71 245/18639 0.00408163265306122 1.07151480310434 0.609850946025356 0.657779430881764 GO:0140855 histone H3S57 kinase activity 1/71 245/18639 0.00408163265306122 1.07151480310434 0.609850946025356 0.657779430881764 GO:0140995 histone H2A kinase activity 1/71 245/18639 0.00408163265306122 1.07151480310434 0.609850946025356 0.657779430881764 GO:0140997 histone H4 kinase activity 1/71 245/18639 0.00408163265306122 1.07151480310434 0.609850946025356 0.657779430881764 GO:0140998 histone H2B kinase activity 1/71 245/18639 0.00408163265306122 1.07151480310434 0.609850946025356 0.657779430881764 GO:1990244 histone H2AT120 kinase activity 1/71 245/18639 0.00408163265306122 1.07151480310434 0.609850946025356 0.657779430881764 GO:0004677 DNA-dependent protein kinase activity 1/71 246/18639 0.0040650406504065 1.06715905187221 0.611356903556736 0.657779430881764 GO:0140857 histone H3T45 kinase activity 1/71 246/18639 0.0040650406504065 1.06715905187221 0.611356903556736 0.657779430881764 GO:0035402 histone H3T11 kinase activity 1/71 247/18639 0.00404858299595142 1.06283856988082 0.612857129721444 0.657779430881764 GO:0035403 histone H3T6 kinase activity 1/71 247/18639 0.00404858299595142 1.06283856988082 0.612857129721444 0.657779430881764 GO:0004679 AMP-activated protein kinase activity 1/71 248/18639 0.00403225806451613 1.05855293048614 0.614351646021453 0.657779430881764 GO:0042277 peptide binding 1/71 249/18639 0.00401606425702811 1.05430171389784 0.615840473879236 0.657779430881764 GO:0140104 molecular carrier activity 1/71 249/18639 0.00401606425702811 1.05430171389784 0.615840473879236 0.657779430881764 GO:0003730 mRNA 3'-UTR binding 1/71 262/18639 0.00381679389312977 1.00198903343726 0.634687192096682 0.675488511588612 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 1/71 268/18639 0.00373134328358209 0.979556443136431 0.643075319120506 0.681980231665163 GO:0008017 microtubule binding 1/71 276/18639 0.0036231884057971 0.951163502755664 0.653964742273954 0.69106912481432 GO:0001217 DNA-binding transcription repressor activity 1/71 278/18639 0.00359712230215827 0.944320599858142 0.656635512084745 0.691439514492064 GO:0015291 secondary active transmembrane transporter activity 1/71 287/18639 0.00348432055749129 0.914707758747608 0.668404640600355 0.701354165136992 GO:0031625 ubiquitin protein ligase binding 1/71 302/18639 0.0033112582781457 0.869275254174051 0.687142183518766 0.718485511188043 GO:0044389 ubiquitin-like protein ligase binding 1/71 322/18639 0.0031055900621118 0.815283002361998 0.710510462381049 0.740322090173261 GO:0003924 GTPase activity 1/71 331/18639 0.00302114803625378 0.793115186587805 0.720456449955745 0.748069763368683 GO:0045296 cadherin binding 1/71 334/18639 0.0029940119760479 0.785991397486717 0.723696311767283 0.748439500992455 GO:0140097 catalytic activity, acting on DNA 1/71 336/18639 0.00297619047619048 0.781312877263581 0.725835623445703 0.748439500992455 GO:0061630 ubiquitin protein ligase activity 1/71 353/18639 0.0028328611898017 0.743685911503012 0.743372613166531 0.763879443874573 GO:0106310 protein serine kinase activity 1/71 361/18639 0.00277008310249307 0.727205337286879 0.751237971232869 0.768642910030973 GO:0042578 phosphoric ester hydrolase activity 1/71 363/18639 0.00275482093663912 0.723198696310092 0.753166878285383 0.768642910030973 GO:0061659 ubiquitin-like protein ligase activity 1/71 372/18639 0.00268817204301075 0.705701953657428 0.761666054061345 0.774663768294474 GO:0004674 protein serine/threonine kinase activity 1/71 433/18639 0.0023094688221709 0.606284357414696 0.812134763604141 0.823184216170184 GO:0004842 ubiquitin-protein transferase activity 1/71 449/18639 0.0022271714922049 0.584679569622636 0.823524852228439 0.829782689044893 GO:0046873 metal ion transmembrane transporter activity 1/71 450/18639 0.00222222222222222 0.583380281690141 0.824213677709021 0.829782689044893 GO:0019787 ubiquitin-like protein transferase activity 1/71 479/18639 0.00208768267223382 0.548060807433326 0.843076281500391 0.845914922178844 GO:0016755 aminoacyltransferase activity 1/71 496/18639 0.00201612903225806 0.529276465243071 0.853190565807867 0.853190565807867