category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Human Diseases	Infectious disease: bacterial	hsa05133	Pertussis	8/95	78/9376	10.1225371120108	C1QC/JUN/C1QB/FOS/C1QA/IL1B/CALM2/SERPING1	8.1849913306388
Human Diseases	Immune disease	hsa05323	Rheumatoid arthritis	8/95	95/9376	8.31113573407202	JUN/FOS/CXCL3/HLA-DRA/HLA-DQA2/IL1B/CCL3/CXCL2	7.24601648338723
Human Diseases	Infectious disease: parasitic	hsa05142	Chagas disease	8/95	103/9376	7.66561062851303	C1QC/JUN/C1QB/FOS/C1QA/IL1B/NFKBIA/CCL3	6.88174344297317
Human Diseases	Infectious disease: parasitic	hsa05140	Leishmaniasis	7/95	78/9376	8.85721997300945	JUN/FOS/HLA-DRA/HLA-DQA2/IL1B/NFKBIA/FCGR2A	7.04971397456215
Organismal Systems	Immune system	hsa04620	Toll-like receptor signaling pathway	8/95	109/9376	7.24365041042974	JUN/SPP1/FOS/IL1B/CCL4/NFKBIA/CCL3/CCL4L1	6.63334064450958
Organismal Systems	Immune system	hsa04659	Th17 cell differentiation	8/95	109/9376	7.24365041042974	JUN/FOS/HLA-DRA/HLA-DQA2/IL1B/NFKBIA/IL1R1/IL6ST	6.63334064450958
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	11/95	238/9376	4.56152145068554	C1QC/JUN/C1QB/CFD/FOS/C1QA/IL1B/NFKBIA/RPL12/IL6ST/FCGR2A	5.63052019604802
Organismal Systems	Immune system	hsa04610	Complement and coagulation cascades	7/95	88/9376	7.85071770334928	C1QC/C1QB/CFD/VSIG4/PLAUR/C1QA/SERPING1	6.53230357104912
Organismal Systems	Immune system	hsa04657	IL-17 signaling pathway	7/95	94/9376	7.34960806270997	JUN/S100A8/FOS/CXCL3/IL1B/NFKBIA/CXCL2	6.259506835569
Human Diseases	Infectious disease: bacterial	hsa05150	Staphylococcus aureus infection	7/95	99/9376	6.97841573631047	C1QC/C1QB/CFD/HLA-DRA/HLA-DQA2/C1QA/FCGR2A	6.04992493173043
Environmental Information Processing	Signaling molecules and interaction	hsa04061	Viral protein interaction with cytokine and cytokine receptor	7/95	100/9376	6.90863157894737	CXCL14/CXCL3/CCL4/CCL3/CXCL2/IL6ST/CCL4L1	6.00975262425681
Environmental Information Processing	Signal transduction	hsa04064	NF-kappa B signaling pathway	7/95	105/9376	6.57964912280702	CXCL3/IL1B/CCL4/NFKBIA/IL1R1/CXCL2/CCL4L1	5.81685586506078
Organismal Systems	Immune system	hsa04612	Antigen processing and presentation	6/95	82/9376	7.22156611039795	IFI30/CD74/CTSB/HLA-DRA/HLA-DQA2/LGMN	5.72473472445732
Environmental Information Processing	Signal transduction	hsa04668	TNF signaling pathway	7/95	119/9376	5.80557275541796	JUN/FOS/CXCL3/MMP14/IL1B/NFKBIA/CXCL2	5.33744680987142
Environmental Information Processing	Signaling molecules and interaction	hsa04060	Cytokine-cytokine receptor interaction	11/95	298/9376	3.64309431296362	CXCL14/CXCL3/IL1B/CCL4/CCL3/PRLR/TNFRSF12A/IL1R1/CXCL2/IL6ST/CCL4L1	4.69111152217105
Human Diseases	Cardiovascular disease	hsa05417	Lipid and atherosclerosis	9/95	216/9376	4.11228070175439	JUN/FOS/CXCL3/IL1B/NFKBIA/CCL3/CALM2/OLR1/CXCL2	4.68174713155035
Human Diseases	Cardiovascular disease	hsa05418	Fluid shear stress and atherosclerosis	7/95	142/9376	4.86523350630096	JUN/FOS/MMP2/IL1B/CALM2/IL1R1/GSTP1	4.69542628941165
Human Diseases	Infectious disease: parasitic	hsa05146	Amoebiasis	6/95	103/9376	5.74920797138477	CXCL3/IL1B/HSPB1/IL1R1/FN1/CXCL2	4.90320131760891
Human Diseases	Endocrine and metabolic disease	hsa04936	Alcoholic liver disease	7/95	144/9376	4.79766081871345	C1QC/C1QB/CXCL3/C1QA/IL1B/NFKBIA/CXCL2	4.64621793110171
Cellular Processes	Cell growth and death	hsa04216	Ferroptosis	4/95	42/9376	9.39949874686717	FTL/FTH1/SLC40A1/SAT1	5.51942925376084
Human Diseases	Endocrine and metabolic disease	hsa04940	Type I diabetes mellitus	4/95	44/9376	8.97224880382775	HLA-DRA/HLA-DQA2/GZMB/IL1B	5.36253169049638
Human Diseases	Immune disease	hsa05332	Graft-versus-host disease	4/95	45/9376	8.77286549707602	HLA-DRA/HLA-DQA2/GZMB/IL1B	5.28777989621532
Human Diseases	Infectious disease: viral	hsa05166	Human T-cell leukemia virus 1 infection	8/95	224/9376	3.52481203007519	JUN/EGR1/FOS/HLA-DRA/HLA-DQA2/NFKBIA/IL1R1/TLN1	3.86941319931611
Human Diseases	Infectious disease: bacterial	hsa05134	Legionellosis	4/95	56/9376	7.04962406015038	CXCL3/IL1B/NFKBIA/CXCL2	4.59371977673662
Cellular Processes	Cell motility	hsa04820	Cytoskeleton in muscle cells	8/95	233/9376	3.3886604924328	DCN/VCAN/LMOD1/TPM1/FBN1/SYNPO2/FN1/TLN1	3.73540831924186
Organismal Systems	Immune system	hsa04658	Th1 and Th2 cell differentiation	5/95	93/9376	5.30616864742501	JUN/FOS/HLA-DRA/HLA-DQA2/NFKBIA	4.22219598231239
Organismal Systems	Endocrine system	hsa04912	GnRH signaling pathway	5/95	93/9376	5.30616864742501	JUN/EGR1/MMP14/MMP2/CALM2	4.22219598231239
Cellular Processes	Cell growth and death	hsa04210	Apoptosis	6/95	137/9376	4.32239723396081	JUN/FOS/CTSB/GZMB/NFKBIA/CTSH	3.96323122633108
Human Diseases	Infectious disease: bacterial	hsa05135	Yersinia infection	6/95	138/9376	4.29107551487414	JUN/FOS/IL1B/NFKBIA/FN1/FCGR2A	3.94038326743673
Organismal Systems	Immune system	hsa04621	NOD-like receptor signaling pathway	7/95	187/9376	3.69445538981143	JUN/CXCL3/ANTXR1/CTSB/IL1B/NFKBIA/CXCL2	3.76537062068404
Organismal Systems	Development and regeneration	hsa04380	Osteoclast differentiation	6/95	142/9376	4.17020014825797	JUN/FOS/IL1B/NFKBIA/IL1R1/FCGR2A	3.85111044250275
Human Diseases	Immune disease	hsa05322	Systemic lupus erythematosus	6/95	143/9376	4.14103790945896	C1QC/C1QB/HLA-DRA/HLA-DQA2/C1QA/FCGR2A	3.82930389446555
Organismal Systems	Immune system	hsa04062	Chemokine signaling pathway	7/95	193/9376	3.57960185437687	CXCL14/CXCL3/CCL4/NFKBIA/CCL3/CXCL2/CCL4L1	3.66344012045615
Human Diseases	Endocrine and metabolic disease	hsa04933	AGE-RAGE signaling pathway in diabetic complications	5/95	101/9376	4.88587806149036	JUN/EGR1/MMP2/IL1B/FN1	3.97230832638292
Human Diseases	Infectious disease: viral	hsa05167	Kaposi sarcoma-associated herpesvirus infection	7/95	196/9376	3.52481203007519	JUN/FOS/CXCL3/NFKBIA/CALM2/CXCL2/IL6ST	3.61398046270202
Human Diseases	Cancer: overview	hsa05202	Transcriptional misregulation in cancer	7/95	201/9376	3.43713013877979	IGFBP3/GZMB/NUPR1/NFKBIZ/KLF3/PBX1/NR4A3	3.53365191825826
Human Diseases	Immune disease	hsa05321	Inflammatory bowel disease	4/95	66/9376	5.98149920255183	JUN/HLA-DRA/HLA-DQA2/IL1B	4.1087266304171
Human Diseases	Infectious disease: bacterial	hsa05120	Epithelial cell signaling in Helicobacter pylori infection	4/95	71/9376	5.56026686434396	JUN/CXCL3/NFKBIA/CXCL2	3.9022159364107
Human Diseases	Immune disease	hsa05330	Allograft rejection	3/95	39/9376	7.5919028340081	HLA-DRA/HLA-DQA2/GZMB	4.17339484977506
Human Diseases	Infectious disease: viral	hsa05163	Human cytomegalovirus infection	7/95	227/9376	3.04345003477858	IL1B/CCL4/NFKBIA/CCL3/CALM2/IL1R1/CCL4L1	3.15311777203854
Human Diseases	Infectious disease: viral	hsa05168	Herpes simplex virus 1 infection	6/95	180/9376	3.28982456140351	CD74/HLA-DRA/HLA-DQA2/IL1B/NFKBIA/PILRA	3.1382608225871
Organismal Systems	Immune system	hsa04623	Cytosolic DNA-sensing pathway	4/95	83/9376	4.7563728598605	IL1B/CCL4/NFKBIA/CCL4L1	3.47760159354618
Human Diseases	Infectious disease: bacterial	hsa05152	Tuberculosis	6/95	181/9376	3.27164873509741	CD74/HLA-DRA/HLA-DQA2/IL1B/CALM2/FCGR2A	3.12215638432663
Organismal Systems	Digestive system	hsa04979	Cholesterol metabolism	3/95	52/9376	5.69392712550607	APOC1/APOE/PLTP	3.43389440934156
Human Diseases	Infectious disease: bacterial	hsa05130	Pathogenic Escherichia coli infection	6/95	200/9376	2.96084210526316	JUN/FOS/IL1B/NFKBIA/IL1R1/FCGR2A	2.83583510170317
Human Diseases	Immune disease	hsa05320	Autoimmune thyroid disease	3/95	54/9376	5.48304093567251	HLA-DRA/HLA-DQA2/GZMB	3.34245131078387
Human Diseases	Cancer: overview	hsa05205	Proteoglycans in cancer	6/95	204/9376	2.90278637770898	TIMP3/DCN/LUM/PLAUR/MMP2/FN1	2.77986143609438
Organismal Systems	Immune system	hsa04640	Hematopoietic cell lineage	4/95	100/9376	3.94778947368421	HLA-DRA/HLA-DQA2/IL1B/IL1R1	2.99823830417031
NA	NA	hsa04518	Integrin signaling	5/95	154/9376	3.20437457279562	SPP1/FBN1/FERMT2/FN1/TLN1	2.79050785166536
Organismal Systems	Immune system	hsa04625	C-type lectin receptor signaling pathway	4/95	105/9376	3.75979949874687	JUN/IL1B/NFKBIA/CALM2	2.87712641912532
Organismal Systems	Digestive system	hsa04978	Mineral absorption	3/95	61/9376	4.85383951682485	FTL/FTH1/SLC40A1	3.05504187918557
Human Diseases	Infectious disease: viral	hsa05164	Influenza A	5/95	173/9376	2.85244904167934	HLA-DRA/HLA-DQA2/IL1B/NFKBIA/DNAJB1	2.48802457115841
Human Diseases	Substance dependence	hsa05031	Amphetamine addiction	3/95	69/9376	4.29107551487414	JUN/FOS/CALM2	2.77592411923228
Human Diseases	Drug resistance: antineoplastic	hsa01523	Antifolate resistance	2/95	30/9376	6.57964912280702	IL1B/FOLR2	3.09673956356544
Human Diseases	Immune disease	hsa05310	Asthma	2/95	32/9376	6.16842105263158	HLA-DRA/HLA-DQA2	2.96289673647989
Organismal Systems	Endocrine system	hsa04926	Relaxin signaling pathway	4/95	130/9376	3.03676113360324	JUN/FOS/MMP2/NFKBIA	2.36583735697973
Human Diseases	Infectious disease: viral	hsa05162	Measles	4/95	136/9376	2.90278637770898	JUN/FOS/IL1B/NFKBIA	2.26138005098227
Organismal Systems	Endocrine system	hsa04915	Estrogen signaling pathway	4/95	139/9376	2.84013631200303	JUN/FOS/MMP2/CALM2	2.21127104055585
Human Diseases	Cancer: overview	hsa05235	PD-L1 expression and PD-1 checkpoint pathway in cancer	3/95	90/9376	3.28982456140351	JUN/FOS/NFKBIA	2.20830562661648
Organismal Systems	Immune system	hsa04662	B cell receptor signaling pathway	3/95	91/9376	3.25367264314633	JUN/FOS/NFKBIA	2.18559973602557
Organismal Systems	Digestive system	hsa04970	Salivary secretion	3/95	93/9376	3.18370118845501	CST3/CALM2/LYZ	2.14111781013938
Organismal Systems	Endocrine system	hsa04921	Oxytocin signaling pathway	4/95	154/9376	2.5634996582365	JUN/FOS/CALM2/RGS2	1.97922718136414
Cellular Processes	Transport and catabolism	hsa04145	Phagosome	4/95	155/9376	2.54696095076401	HLA-DRA/HLA-DQA2/OLR1/FCGR2A	1.96474523295121
Cellular Processes	Transport and catabolism	hsa04148	Efferocytosis	4/95	157/9376	2.51451558833389	C1QC/C1QB/C1QA/PBX1	1.93611754684187
Metabolism	Metabolism of cofactors and vitamins	hsa00860	Porphyrin metabolism	2/95	46/9376	4.29107551487414	FTL/FTH1	2.26373713877419
Human Diseases	Drug resistance: antineoplastic	hsa01522	Endocrine resistance	3/95	99/9376	2.99074960127592	JUN/FOS/MMP2	2.01456141172015
Organismal Systems	Sensory system	hsa04750	Inflammatory mediator regulation of TRP channels	3/95	99/9376	2.99074960127592	IL1B/CALM2/IL1R1	2.01456141172015
Environmental Information Processing	Signaling molecules and interaction	hsa04514	Cell adhesion molecule (CAM) interaction	4/95	160/9376	2.46736842105263	VCAN/HLA-DRA/HLA-DQA2/NLGN4X	1.89399130662236
Environmental Information Processing	Signal transduction	hsa04010	MAPK signaling pathway	6/95	300/9376	1.97389473684211	JUN/FOS/FGF7/IL1B/HSPB1/IL1R1	1.73450460447077
Metabolism	Amino acid metabolism	hsa00330	Arginine and proline metabolism	2/95	50/9376	3.94778947368421	SAT1/AOC1	2.11438376179245
Organismal Systems	Immune system	hsa04672	Intestinal immune network for IgA production	2/95	50/9376	3.94778947368421	HLA-DRA/HLA-DQA2	2.11438376179245
Human Diseases	Cancer: specific types	hsa05215	Prostate cancer	3/95	106/9376	2.79324726911619	NFKBIA/FOLR2/GSTP1	1.87846582442393
Human Diseases	Infectious disease: parasitic	hsa05145	Toxoplasmosis	3/95	112/9376	2.64360902255639	HLA-DRA/HLA-DQA2/NFKBIA	1.77034663285591
Human Diseases	Infectious disease: bacterial	hsa05132	Salmonella infection	5/95	248/9376	1.98981324278438	JUN/FOS/IL1B/NFKBIA/RHOB	1.59823758367171
Cellular Processes	Transport and catabolism	hsa04142	Lysosome biogenesis	5/95	250/9376	1.97389473684211	CTSB/LITAF/LGMN/CTSH/PSAP	1.57903532357017
Organismal Systems	Endocrine system	hsa04928	Parathyroid hormone synthesis, secretion and action	3/95	115/9376	2.57464530892448	EGR1/FOS/MMP14	1.7189085677059
Human Diseases	Infectious disease: bacterial	hsa05131	Shigellosis	5/95	253/9376	1.95048887039734	JUN/IL1B/NFKBIA/IL1R1/TLN1	1.55055977637532
Organismal Systems	Nervous system	hsa04722	Neurotrophin signaling pathway	3/95	120/9376	2.46736842105263	JUN/NFKBIA/CALM2	1.63669657287217
Organismal Systems	Immune system	hsa04660	T cell receptor signaling pathway	3/95	122/9376	2.42691975841242	JUN/FOS/NFKBIA	1.60496207256694
Human Diseases	Neurodegenerative disease	hsa05020	Prion disease	5/95	275/9376	1.79444976076555	C1QC/C1QB/EGR1/C1QA/IL1B	1.35281460366884
Cellular Processes	Cellular community - eukaryotes	hsa04510	Focal adhesion	4/95	203/9376	1.94472387866217	JUN/SPP1/FN1/TLN1	1.3767252234739
Human Diseases	Infectious disease: viral	hsa05169	Epstein-Barr virus infection	4/95	205/9376	1.92575096277279	JUN/HLA-DRA/HLA-DQA2/NFKBIA	1.35585363786496
Organismal Systems	Circulatory system	hsa04270	Vascular smooth muscle contraction	3/95	134/9376	2.20958366064415	CALD1/CALM2/RAMP1	1.42677464594101
Organismal Systems	Endocrine system	hsa04924	Renin secretion	2/95	69/9376	2.86071700991609	CTSB/CALM2	1.56945934651074
Human Diseases	Cardiovascular disease	hsa05416	Viral myocarditis	2/95	70/9376	2.81984962406015	HLA-DRA/HLA-DQA2	1.5461550872105
Organismal Systems	Endocrine system	hsa04917	Prolactin signaling pathway	2/95	71/9376	2.78013343217198	FOS/PRLR	1.52325845276125
Environmental Information Processing	Signal transduction	hsa04371	Apelin signaling pathway	3/95	140/9376	2.11488721804511	SPP1/EGR1/CALM2	1.34463077420876
Human Diseases	Infectious disease: viral	hsa05170	Human immunodeficiency virus 1 infection	4/95	214/9376	1.84476143630103	JUN/FOS/NFKBIA/CALM2	1.26472434180854
Organismal Systems	Endocrine system	hsa03320	PPAR signaling pathway	2/95	76/9376	2.59722991689751	OLR1/PLTP	1.41443440776997
Human Diseases	Cancer: specific types	hsa05224	Breast cancer	3/95	148/9376	2.00056899004267	JUN/FOS/FGF7	1.24129257685774
Environmental Information Processing	Signal transduction	hsa04024	cAMP signaling pathway	4/95	226/9376	1.74680950163018	JUN/FOS/NFKBIA/CALM2	1.14975038024011
Metabolism	Amino acid metabolism	hsa00340	Histidine metabolism	1/95	22/9376	4.48612440191388	AOC1	1.65617259086261
Human Diseases	Endocrine and metabolic disease	hsa04932	Non-alcoholic fatty liver disease	3/95	157/9376	1.88588669125042	JUN/FOS/IL1B	1.13249462775783
Human Diseases	Cancer: specific types	hsa05210	Colorectal cancer	2/95	87/9376	2.26884452510587	JUN/FOS	1.2029113134682
Environmental Information Processing	Signaling molecules and interaction	hsa04512	ECM-receptor interaction	2/95	89/9376	2.21785925487877	SPP1/FN1	1.1678967122746
Human Diseases	Infectious disease: viral	hsa05161	Hepatitis B	3/95	163/9376	1.8164675492412	JUN/FOS/NFKBIA	1.06385453534882
Metabolism	Lipid metabolism	hsa01040	Biosynthesis of unsaturated fatty acids	1/95	27/9376	3.65536062378168	FADS1	1.39788957970067
Cellular Processes	Cell growth and death	hsa04217	Necroptosis	3/95	168/9376	1.76240601503759	FTL/FTH1/IL1B	1.00880762019065
Human Diseases	Cancer: specific types	hsa05222	Small cell lung cancer	2/95	93/9376	2.12246745897001	NFKBIA/FN1	1.10057872405288
Organismal Systems	Sensory system	hsa04744	Phototransduction	1/95	29/9376	3.4032667876588	CALM2	1.31133881650534
Organismal Systems	Environmental adaptation	hsa04713	Circadian entrainment	2/95	97/9376	2.03494302767227	FOS/CALM2	1.03657749897378
Human Diseases	Cancer: overview	hsa05231	Choline metabolism in cancer	2/95	99/9376	1.99383306751728	JUN/FOS	1.00572053171758
NA	NA	hsa04981	Folate transport and metabolism	1/95	31/9376	3.18370118845501	FOLR2	1.23206737888443
Organismal Systems	Digestive system	hsa04974	Protein digestion and absorption	2/95	103/9376	1.91640265712826	COL15A1/SLC7A8	0.946117066880401
Organismal Systems	Environmental adaptation	hsa04710	Circadian rhythm	1/95	34/9376	2.90278637770898	RORB	1.12450040229605
Environmental Information Processing	Signal transduction	hsa04350	TGF-beta signaling pathway	2/95	110/9376	1.79444976076555	DCN/FBN1	0.847943055523603
Human Diseases	Infectious disease: parasitic	hsa05143	African trypanosomiasis	1/95	37/9376	2.6674253200569	IL1B	1.02812784374545
Human Diseases	Cancer: specific types	hsa05219	Bladder cancer	1/95	41/9376	2.40718870346598	MMP2	0.913560180796653
Human Diseases	Cancer: overview	hsa05203	Viral carcinogenesis	3/95	205/9376	1.44431322207959	JUN/NFKBIA/IL6ST	0.650740558458345
Metabolism	Amino acid metabolism	hsa00380	Tryptophan metabolism	1/95	42/9376	2.34987468671679	AOC1	0.887021721094345
Organismal Systems	Endocrine system	hsa04935	Growth hormone synthesis, secretion and action	2/95	122/9376	1.61794650560828	IGFBP3/FOS	0.695050088506736
Environmental Information Processing	Signal transduction	hsa04015	Rap1 signaling pathway	3/95	212/9376	1.39662363455809	FGF7/CALM2/TLN1	0.590954487252989
Organismal Systems	Immune system	hsa04611	Platelet activation	2/95	126/9376	1.56658312447786	FCGR2A/TLN1	0.647780836106975
Human Diseases	Cancer: overview	hsa05207	Chemical carcinogenesis - receptor activation	3/95	217/9376	1.36444336648072	JUN/FOS/FGF7	0.549523085176207
NA	NA	hsa04081	Hormone signaling	3/95	219/9376	1.3519826964672	SLC40A1/PRLR/RAMP1	0.533232754734416
Organismal Systems	Nervous system	hsa04728	Dopaminergic synapse	2/95	133/9376	1.48413138108429	FOS/CALM2	0.568895675833802
Human Diseases	Substance dependence	hsa05030	Cocaine addiction	1/95	49/9376	2.01417830290011	JUN	0.720097695810566
Human Diseases	Infectious disease: parasitic	hsa05144	Malaria	1/95	50/9376	1.97389473684211	IL1B	0.698553012573337
Human Diseases	Cancer: overview	hsa05208	Chemical carcinogenesis - reactive oxygen species	3/95	227/9376	1.30433572919082	JUN/FOS/NFKBIA	0.469601105995165
Cellular Processes	Cell motility	hsa04810	Regulation of actin cytoskeleton	3/95	232/9376	1.27622504537205	TMSB4X/FGF7/FN1	0.431011632920589
Metabolism	Lipid metabolism	hsa00600	Sphingolipid metabolism	1/95	55/9376	1.79444976076555	PSAP	0.597814691629555
Metabolism	Global and overview maps	hsa01212	Fatty acid metabolism	1/95	57/9376	1.731486611265	FADS1	0.560414299154051
Metabolism	Metabolism of other amino acids	hsa00480	Glutathione metabolism	1/95	59/9376	1.67279214986619	GSTP1	0.524467918914527
Environmental Information Processing	Signal transduction	hsa04370	VEGF signaling pathway	1/95	60/9376	1.64491228070175	HSPB1	0.507004234773061
Organismal Systems	Circulatory system	hsa04261	Adrenergic signaling in cardiomyocytes	2/95	154/9376	1.28174982911825	TPM1/CALM2	0.356665840761693
Cellular Processes	Transport and catabolism	hsa04144	Endocytosis	3/95	250/9376	1.18433684210526	RAB31/FOLR2/DAB2	0.298876638417216
Cellular Processes	Cell growth and death	hsa04218	Cellular senescence	2/95	157/9376	1.25725779416695	IGFBP3/CALM2	0.32887170867379
Organismal Systems	Endocrine system	hsa04927	Cortisol synthesis and secretion	1/95	65/9376	1.51838056680162	PBX1	0.424284612688612
Organismal Systems	Endocrine system	hsa04929	GnRH secretion	1/95	65/9376	1.51838056680162	SPP1	0.424284612688612
Organismal Systems	Nervous system	hsa04720	Long-term potentiation	1/95	67/9376	1.47305577376276	CALM2	0.393140954938939
Environmental Information Processing	Signal transduction	hsa04151	PI3K-Akt signaling pathway	4/95	362/9376	1.0905495783658	SPP1/FGF7/PRLR/FN1	0.177759162444478
Environmental Information Processing	Signal transduction	hsa04022	cGMP-PKG signaling pathway	2/95	166/9376	1.18909321496512	CALM2/RGS2	0.248685365683025
Environmental Information Processing	Signal transduction	hsa04630	JAK-STAT signaling pathway	2/95	168/9376	1.1749373433584	PRLR/IL6ST	0.231475252759065
Organismal Systems	Endocrine system	hsa04920	Adipocytokine signaling pathway	1/95	70/9376	1.40992481203008	NFKBIA	0.348274563521387
Human Diseases	Cancer: overview	hsa05204	Chemical carcinogenesis - DNA adducts	1/95	70/9376	1.40992481203008	GSTP1	0.348274563521387
Human Diseases	Cancer: specific types	hsa05211	Renal cell carcinoma	1/95	70/9376	1.40992481203008	JUN	0.348274563521387
Organismal Systems	Immune system	hsa04622	RIG-I-like receptor signaling pathway	1/95	72/9376	1.37076023391813	NFKBIA	0.319502749129041
Metabolism	Xenobiotics biodegradation and metabolism	hsa00982	Drug metabolism - cytochrome P450	1/95	73/9376	1.3519826964672	GSTP1	0.305436748688079
Human Diseases	Cancer: specific types	hsa05218	Melanoma	1/95	73/9376	1.3519826964672	FGF7	0.305436748688079
Genetic Information Processing	Folding, sorting and degradation	hsa04141	Protein processing in endoplasmic reticulum	2/95	174/9376	1.13442226255293	DNAJB1/DNAJA1	0.181073445379419
Human Diseases	Drug resistance: antineoplastic	hsa01524	Platinum drug resistance	1/95	75/9376	1.3159298245614	GSTP1	0.277911482112658
Cellular Processes	Cell growth and death	hsa04115	p53 signaling pathway	1/95	75/9376	1.3159298245614	IGFBP3	0.277911482112658
Organismal Systems	Digestive system	hsa04971	Gastric acid secretion	1/95	76/9376	1.29861495844875	CALM2	0.26443987020049
Human Diseases	Cancer: specific types	hsa05214	Glioma	1/95	76/9376	1.29861495844875	CALM2	0.26443987020049
Environmental Information Processing	Signal transduction	hsa04310	Wnt signaling pathway	2/95	178/9376	1.10892962743938	JUN/DKK1	0.14844287987235
Human Diseases	Cancer: specific types	hsa05220	Chronic myeloid leukemia	1/95	77/9376	1.28174982911825	NFKBIA	0.251154494578409
Human Diseases	Infectious disease: bacterial	hsa05100	Bacterial invasion of epithelial cells	1/95	78/9376	1.26531713900135	FN1	0.23804983810225
Metabolism	Xenobiotics biodegradation and metabolism	hsa00980	Metabolism of xenobiotics by cytochrome P450	1/95	79/9376	1.24930046635576	GSTP1	0.225120619699944
Human Diseases	Neurodegenerative disease	hsa05010	Alzheimer disease	4/95	388/9376	1.01747151383614	APOE/DKK1/IL1B/CALM2	0.0355602595284196
Metabolism	Xenobiotics biodegradation and metabolism	hsa00983	Drug metabolism - other enzymes	1/95	82/9376	1.20359435173299	GSTP1	0.187336055647037
Environmental Information Processing	Signal transduction	hsa04012	ErbB signaling pathway	1/95	86/9376	1.14761321909425	JUN	0.139128683099896
Organismal Systems	Circulatory system	hsa04260	Cardiac muscle contraction	1/95	87/9376	1.13442226255293	TPM1	0.127437252718907
Environmental Information Processing	Signal transduction	hsa04070	Phosphatidylinositol signaling system	1/95	98/9376	1.00708915145005	CALM2	0.00713723773278916
Organismal Systems	Immune system	hsa04666	Fc gamma R-mediated phagocytosis	1/95	98/9376	1.00708915145005	FCGR2A	0.00713723773278916
Organismal Systems	Endocrine system	hsa04925	Aldosterone synthesis and secretion	1/95	98/9376	1.00708915145005	CALM2	0.00713723773278916
Human Diseases	Cardiovascular disease	hsa05410	Hypertrophic cardiomyopathy	1/95	99/9376	0.996916533758639	TPM1	-0.00312034828499086
Organismal Systems	Endocrine system	hsa04916	Melanogenesis	1/95	101/9376	0.977175612298072	CALM2	-0.0233320510521082
NA	NA	hsa04382	Cornified envelope formation	2/95	217/9376	0.909628910987145	S100A8/S100A6	-0.136265341099863
Cellular Processes	Transport and catabolism	hsa04137	Mitophagy - animal	1/95	105/9376	0.939949874686717	JUN	-0.06260302681013
Human Diseases	Cardiovascular disease	hsa05414	Dilated cardiomyopathy	1/95	105/9376	0.939949874686717	TPM1	-0.06260302681013
Genetic Information Processing	Translation	hsa03010	Ribosome	2/95	222/9376	0.8891417733523	MT-RNR2/RPL12	-0.169117680986756
Organismal Systems	Endocrine system	hsa04922	Glucagon signaling pathway	1/95	107/9376	0.922380718150516	CALM2	-0.0816949332958714
Human Diseases	Endocrine and metabolic disease	hsa04931	Insulin resistance	1/95	109/9376	0.905456301303718	NFKBIA	-0.100444534530105
Environmental Information Processing	Signal transduction	hsa04066	HIF-1 signaling pathway	1/95	110/9376	0.897224880382775	TIMP1	-0.109695355532685
Organismal Systems	Nervous system	hsa04725	Cholinergic synapse	1/95	115/9376	0.858215102974828	FOS	-0.154774712048854
Organismal Systems	Immune system	hsa04670	Leukocyte transendothelial migration	1/95	116/9376	0.850816696914701	MMP2	-0.163566279197084
Environmental Information Processing	Signal transduction	hsa04014	Ras signaling pathway	2/95	238/9376	0.829367536488279	FGF7/CALM2	-0.269758176444294
Environmental Information Processing	Signal transduction	hsa04020	Calcium signaling pathway	2/95	254/9376	0.777123912142561	FGF7/CALM2	-0.364321964299153
Organismal Systems	Immune system	hsa04650	Natural killer cell mediated cytotoxicity	1/95	133/9376	0.742065690542145	GZMB	-0.303094818954121
Cellular Processes	Cell growth and death	hsa04114	Oocyte meiosis	1/95	138/9376	0.715179252479024	CALM2	-0.34101402495269
Organismal Systems	Endocrine system	hsa04910	Insulin signaling pathway	1/95	138/9376	0.715179252479024	CALM2	-0.34101402495269
Cellular Processes	Cellular community - eukaryotes	hsa04550	Signaling pathways regulating pluripotency of stem cells	1/95	144/9376	0.685380116959064	IL6ST	-0.384919194168882
NA	NA	hsa04519	Cadherin signaling	3/95	404/9376	0.732881709223554	CDH11/NFKBIA/LIMA1	-0.555264274113089
Human Diseases	Cancer: specific types	hsa05226	Gastric cancer	1/95	150/9376	0.657964912280702	FGF7	-0.427227912765316
Human Diseases	Endocrine and metabolic disease	hsa04934	Cushing syndrome	1/95	155/9376	0.636740237691002	PBX1	-0.461364513413935
Human Diseases	Infectious disease: viral	hsa05160	Hepatitis C	1/95	156/9376	0.632658569500675	NFKBIA	-0.468076465866467
Cellular Processes	Transport and catabolism	hsa04140	Autophagy - animal	1/95	169/9376	0.583992525692931	CTSB	-0.552122529249997
Cellular Processes	Cellular community - eukaryotes	hsa04530	Tight junction	1/95	170/9376	0.580557275541796	JUN	-0.55835665338049
Human Diseases	Cancer: specific types	hsa05225	Hepatocellular carcinoma	1/95	170/9376	0.580557275541796	GSTP1	-0.55835665338049
Human Diseases	Cancer: overview	hsa05206	MicroRNAs in cancer	2/95	323/9376	0.611112921622943	TIMP3/TPM1	-0.719579145752836
Human Diseases	Infectious disease: viral	hsa05165	Human papillomavirus infection	2/95	333/9376	0.592761182234867	SPP1/FN1	-0.765535039755395
Human Diseases	Substance dependence	hsa05034	Alcoholism	1/95	191/9376	0.516726370901075	CALM2	-0.682684834541389
Cellular Processes	Cell motility	hsa04814	Motor proteins	1/95	194/9376	0.508735756918068	TPM1	-0.699515641874574
Organismal Systems	Immune system	hsa04613	Neutrophil extracellular trap formation	1/95	195/9376	0.50612685560054	FCGR2A	-0.705078996021463
NA	NA	hsa04082	Neuroactive ligand signaling	1/95	199/9376	0.495953451467866	P2RY14	-0.727104566365137
Human Diseases	Neurodegenerative disease	hsa05022	Pathways of neurodegeneration - multiple diseases	3/95	480/9376	0.616842105263158	DKK1/IL1B/CALM2	-0.871868655076779
Human Diseases	Cardiovascular disease	hsa05415	Diabetic cardiomyopathy	1/95	205/9376	0.481437740693196	MMP2	-0.759485600354885
Environmental Information Processing	Signaling molecules and interaction	hsa04080	Neuroactive ligand-receptor interaction	2/95	370/9376	0.53348506401138	P2RY14/PRLR	-0.926297512841268
Human Diseases	Neurodegenerative disease	hsa05012	Parkinson disease	1/95	268/9376	0.368263943440691	CALM2	-1.06155281341217
Organismal Systems	Sensory system	hsa04740	Olfactory transduction	2/95	449/9376	0.439620208650803	CALM2/RGS2	-1.23112718944401
NA	NA	hsa04517	IgSF CAM signaling	1/95	299/9376	0.330082731913396	NLGN4X	-1.1910655226325
Human Diseases	Neurodegenerative disease	hsa05016	Huntington disease	1/95	308/9376	0.320437457279563	TGM2	-1.22687153308535