ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0031994 insulin-like growth factor I binding 6/142 13/18639 0.461538461538462 60.5817984832069 2.88740068370801e-10 1.06545085228826e-07 GO:0005520 insulin-like growth factor binding 6/142 19/18639 0.315789473684211 41.4507042253521 4.39674699116992e-09 8.1119981987085e-07 GO:0050840 extracellular matrix binding 7/142 67/18639 0.104477611940299 13.71379020391 7.62448273104711e-07 9.11603121738155e-05 GO:0019838 growth factor binding 9/142 136/18639 0.0661764705882353 8.68636081193041 9.88187665840819e-07 9.11603121738155e-05 GO:0005539 glycosaminoglycan binding 11/142 242/18639 0.0454545454545455 5.96638924455826 2.51826258840248e-06 0.000179778742850395 GO:0001968 fibronectin binding 5/142 30/18639 0.166666666666667 21.8767605633803 2.92323159106334e-06 0.000179778742850395 GO:0008201 heparin binding 9/142 172/18639 0.0523255813953488 6.86828529315428 6.8753110679642e-06 0.000362427112011256 GO:0005518 collagen binding 6/142 72/18639 0.0833333333333333 10.9383802816901 1.8175372293871e-05 0.000766984498600185 GO:0033218 amide binding 10/142 247/18639 0.0404858299595142 5.31419284940412 2.00245605896694e-05 0.000766984498600185 GO:0030021 extracellular matrix structural constituent conferring compression resistance 4/142 22/18639 0.181818181818182 23.865556978233 2.12297749543809e-05 0.000766984498600185 GO:0008009 chemokine activity 5/142 45/18639 0.111111111111111 14.5845070422535 2.28640365436369e-05 0.000766984498600185 GO:0140375 immune receptor activity 8/142 156/18639 0.0512820512820513 6.73131094257855 2.61533834697135e-05 0.00080421654169369 GO:0005178 integrin binding 8/142 161/18639 0.0496894409937888 6.52226401889598 3.27940383924541e-05 0.00093084616667812 GO:0050750 low-density lipoprotein particle receptor binding 4/142 26/18639 0.153846153846154 20.1939328277356 4.23732556302503e-05 0.00109261874672289 GO:0005201 extracellular matrix structural constituent 8/142 168/18639 0.0476190476190476 6.25050301810865 4.44153962082478e-05 0.00109261874672289 GO:1901681 sulfur compound binding 10/142 275/18639 0.0363636363636364 4.77311139564661 4.98713592006862e-05 0.00115015822156583 GO:0070325 lipoprotein particle receptor binding 4/142 31/18639 0.129032258064516 16.9368468877783 8.65845045400292e-05 0.00187939306913358 GO:0038024 cargo receptor activity 5/142 65/18639 0.0769230769230769 10.0969664138678 0.000136811685264831 0.00277013516617121 GO:0008191 metalloendopeptidase inhibitor activity 3/142 14/18639 0.214285714285714 28.1272635814889 0.000148178383107525 0.00277013516617121 GO:0003779 actin binding 12/142 443/18639 0.0270880361173815 3.55559088163291 0.000150142827434754 0.00277013516617121 GO:0005523 tropomyosin binding 3/142 15/18639 0.2 26.2521126760563 0.000184190656505073 0.00323649296430343 GO:0004222 metalloendopeptidase activity 6/142 110/18639 0.0545454545454545 7.15966709346991 0.000196662725787895 0.00329857026435151 GO:0042379 chemokine receptor binding 5/142 72/18639 0.0694444444444444 9.11531690140845 0.000222072534824984 0.00356281588480084 GO:0004175 endopeptidase activity 11/142 405/18639 0.0271604938271605 3.56510172143975 0.000278360859075413 0.00427979820828448 GO:0033293 monocarboxylic acid binding 5/142 79/18639 0.0632911392405063 8.30763059368872 0.000342795243956281 0.00488418189596475 GO:0061134 peptidase regulator activity 8/142 226/18639 0.0353982300884956 4.64639162408077 0.000344142897818655 0.00488418189596475 GO:0005125 cytokine activity 8/142 234/18639 0.0341880341880342 4.4875406283857 0.000433924678201929 0.00588574666930607 GO:0005504 fatty acid binding 4/142 47/18639 0.0851063829787234 11.1711117770453 0.000446614923416179 0.00588574666930607 GO:0072542 protein phosphatase activator activity 3/142 21/18639 0.142857142857143 18.751509054326 0.000520668884434951 0.00650318974573616 GO:0008237 metallopeptidase activity 7/142 184/18639 0.0380434782608696 4.99360838946724 0.000528714613474485 0.00650318974573616 GO:0031406 carboxylic acid binding 7/142 187/18639 0.0374331550802139 4.91349702493033 0.000582121634866793 0.00692912526664021 GO:0002020 protease binding 6/142 136/18639 0.0441176470588235 5.7909072079536 0.000614043796566923 0.00693326969605233 GO:0043177 organic acid binding 7/142 189/18639 0.037037037037037 4.86150234741784 0.000620048509403054 0.00693326969605233 GO:0042277 peptide binding 8/142 249/18639 0.0321285140562249 4.21720685559138 0.000653336294235241 0.00709062036978835 GO:0019211 phosphatase activator activity 3/142 25/18639 0.12 15.7512676056338 0.000880556057680066 0.00928357672239841 GO:0019865 immunoglobulin binding 3/142 26/18639 0.115384615384615 15.1454496208017 0.000989884249251782 0.0101463135548308 GO:0023026 MHC class II protein complex binding 3/142 27/18639 0.111111111111111 14.5845070422535 0.00110743863393026 0.0110444555654126 GO:0005126 cytokine receptor binding 8/142 275/18639 0.0290909090909091 3.81848911651729 0.00123977059214133 0.0120388249605303 GO:0004857 enzyme inhibitor activity 10/142 416/18639 0.0240384615384615 3.15530200433369 0.00133807139183052 0.0125852113742058 GO:0019888 protein phosphatase regulator activity 5/142 107/18639 0.0467289719626168 6.13367118599447 0.00136425055546947 0.0125852113742058 GO:0008083 growth factor activity 6/142 162/18639 0.037037037037037 4.86150234741784 0.00152078354804941 0.0136870519324447 GO:0019208 phosphatase regulator activity 5/142 117/18639 0.0427350427350427 5.60942578548212 0.00202390787285495 0.0177814763115113 GO:0032395 MHC class II receptor activity 2/142 10/18639 0.2 26.2521126760563 0.00249167302198258 0.0213820312816645 GO:0044183 protein folding chaperone 4/142 75/18639 0.0533333333333333 7.00056338028169 0.00258215700687687 0.0216549076258538 GO:0023023 MHC protein complex binding 3/142 37/18639 0.0810810810810811 10.642748382185 0.00278284296738836 0.0223232403253545 GO:0043394 proteoglycan binding 3/142 37/18639 0.0810810810810811 10.642748382185 0.00278284296738836 0.0223232403253545 GO:0061135 endopeptidase regulator activity 6/142 184/18639 0.0326086956521739 4.28023576240049 0.00288297254441359 0.0223628700284512 GO:0008199 ferric iron binding 2/142 11/18639 0.181818181818182 23.865556978233 0.00303019919084704 0.0223628700284512 GO:0010854 adenylate cyclase regulator activity 2/142 11/18639 0.181818181818182 23.865556978233 0.00303019919084704 0.0223628700284512 GO:0019864 IgG binding 2/142 11/18639 0.181818181818182 23.865556978233 0.00303019919084704 0.0223628700284512 GO:0046332 SMAD binding 4/142 79/18639 0.0506329113924051 6.64610447495097 0.00311817941718603 0.0225609451949342 GO:0035497 cAMP response element binding 2/142 12/18639 0.166666666666667 21.8767605633803 0.00361812591357425 0.0256747781174788 GO:0001540 amyloid-beta binding 4/142 83/18639 0.0481927710843374 6.32581028338707 0.00372556744006712 0.0259383846299012 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 10/142 484/18639 0.0206611570247934 2.71199511116284 0.00399562457018801 0.0268313293280836 GO:0042056 chemoattractant activity 3/142 42/18639 0.0714285714285714 9.37575452716298 0.00399924962884715 0.0268313293280836 GO:0001216 DNA-binding transcription activator activity 10/142 491/18639 0.0203665987780041 2.67333122974097 0.00441664490806812 0.029102535197806 GO:0030547 signaling receptor inhibitor activity 3/142 44/18639 0.0681818181818182 8.94958386683739 0.00456298878915057 0.0295393484771326 GO:0042605 peptide antigen binding 3/142 45/18639 0.0666666666666667 8.75070422535211 0.00486195264246726 0.030877205199874 GO:0019955 cytokine binding 5/142 144/18639 0.0347222222222222 4.55765845070423 0.00493700570946495 0.030877205199874 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 8/142 349/18639 0.0229226361031519 3.0088381290609 0.00534318373038612 0.0324355594351814 GO:0051015 actin filament binding 6/142 209/18639 0.0287081339712919 3.76824583866837 0.00536197594998933 0.0324355594351814 GO:0051371 muscle alpha-actinin binding 2/142 15/18639 0.133333333333333 17.5014084507042 0.0056706209346947 0.0337493407242314 GO:0042562 hormone binding 4/142 94/18639 0.0425531914893617 5.58555588852263 0.00579834622145614 0.0339617421542431 GO:0004896 cytokine receptor activity 4/142 96/18639 0.0416666666666667 5.46919014084507 0.00624326870580362 0.035996346131899 GO:0048020 CCR chemokine receptor binding 3/142 50/18639 0.06 7.8756338028169 0.00653262786316631 0.0370852258693595 GO:0017046 peptide hormone binding 3/142 53/18639 0.0566037735849057 7.42984321020462 0.00767967010461776 0.0429363374030902 GO:0004866 endopeptidase inhibitor activity 5/142 161/18639 0.031055900621118 4.07641501180999 0.00784620101752129 0.0432126593353038 GO:0140313 molecular sequestering activity 3/142 55/18639 0.0545454545454545 7.15966709346991 0.0085062523571065 0.0461589282319456 GO:0097001 ceramide binding 2/142 19/18639 0.105263157894737 13.8169014084507 0.00905297180632052 0.0484137187903228 GO:0016504 peptidase activator activity 3/142 57/18639 0.0526315789473684 6.90845070422535 0.00938313153516286 0.0494625076639299 GO:0030414 peptidase inhibitor activity 5/142 169/18639 0.029585798816568 3.88344862071839 0.00955939640052735 0.0496819334055576 GO:0010851 cyclase regulator activity 2/142 20/18639 0.1 13.1260563380282 0.0100089927010771 0.0512960875930199 GO:0004252 serine-type endopeptidase activity 5/142 176/18639 0.0284090909090909 3.72899327784891 0.011256301315496 0.0568982902112056 GO:0140297 DNA-binding transcription factor binding 9/142 488/18639 0.0184426229508197 2.4207890787347 0.012532352281881 0.0624924052974879 GO:0051082 unfolded protein binding 4/142 121/18639 0.0330578512396694 4.33919217786055 0.0138099316889489 0.0679448639096286 GO:0120020 cholesterol transfer activity 2/142 25/18639 0.08 10.5008450704225 0.0154165200427937 0.0748512617867219 GO:0097110 scaffold protein binding 3/142 70/18639 0.0428571428571429 5.62545271629779 0.0163444638920564 0.0766539368305285 GO:0008236 serine-type peptidase activity 5/142 194/18639 0.0257731958762887 3.383004210832 0.016537281962931 0.0766539368305285 GO:0008198 ferrous iron binding 2/142 26/18639 0.0769230769230769 10.0969664138678 0.0166187396922555 0.0766539368305285 GO:0070412 R-SMAD binding 2/142 26/18639 0.0769230769230769 10.0969664138678 0.0166187396922555 0.0766539368305285 GO:0001671 ATPase activator activity 2/142 27/18639 0.0740740740740741 9.72300469483568 0.0178596437769215 0.0805556451770733 GO:0017171 serine hydrolase activity 5/142 198/18639 0.0252525252525253 3.31466069142125 0.0179012544837941 0.0805556451770733 GO:0046625 sphingolipid binding 2/142 28/18639 0.0714285714285714 9.37575452716298 0.0191385818210342 0.084073055856686 GO:0051393 alpha-actinin binding 2/142 28/18639 0.0714285714285714 9.37575452716298 0.0191385818210342 0.084073055856686 GO:0003785 actin monomer binding 2/142 29/18639 0.0689655172413793 9.05245264691598 0.0204549108919711 0.0877658385946202 GO:0043236 laminin binding 2/142 29/18639 0.0689655172413793 9.05245264691598 0.0204549108919711 0.0877658385946202 GO:0031210 phosphatidylcholine binding 2/142 30/18639 0.0666666666666667 8.75070422535211 0.0218079955243997 0.0914900378209584 GO:0070851 growth factor receptor binding 4/142 139/18639 0.0287769784172662 3.77728239943257 0.0218187624071662 0.0914900378209584 GO:0048306 calcium-dependent protein binding 3/142 80/18639 0.0375 4.92227112676056 0.0232261739741727 0.0962972831064013 GO:0071813 lipoprotein particle binding 2/142 32/18639 0.0625 8.20378521126761 0.0246219264987129 0.0987553356307071 GO:0071814 protein-lipid complex binding 2/142 32/18639 0.0625 8.20378521126761 0.0246219264987129 0.0987553356307071 GO:0120015 sterol transfer activity 2/142 32/18639 0.0625 8.20378521126761 0.0246219264987129 0.0987553356307071 GO:0140311 protein sequestering activity 2/142 33/18639 0.0606060606060606 7.95518565941101 0.0260815385736117 0.102383912060242 GO:0140416 transcription regulator inhibitor activity 2/142 33/18639 0.0606060606060606 7.95518565941101 0.0260815385736117 0.102383912060242 GO:0001664 G protein-coupled receptor binding 6/142 297/18639 0.0202020202020202 2.651728553137 0.0263632849711371 0.102400548993154 GO:0004197 cysteine-type endopeptidase activity 3/142 88/18639 0.0340909090909091 4.47479193341869 0.0296984078747337 0.114153255268507 GO:0042805 actinin binding 2/142 37/18639 0.0540540540540541 7.09516558812333 0.0322568983223331 0.122709231762278 GO:0004177 aminopeptidase activity 2/142 40/18639 0.05 6.56302816901408 0.0372257861172503 0.138750657346115 GO:0050997 quaternary ammonium group binding 2/142 40/18639 0.05 6.56302816901408 0.0372257861172503 0.138750657346115 GO:0042287 MHC protein binding 2/142 41/18639 0.0487804878048781 6.40295431123325 0.0389433030245974 0.143700788160765 GO:0048156 tau protein binding 2/142 43/18639 0.0465116279069767 6.1051424828038 0.0424668491465852 0.155151161733564 GO:0008238 exopeptidase activity 3/142 102/18639 0.0294117647058824 3.8606048053024 0.0430689216232053 0.15580815763689 GO:0060590 ATPase regulator activity 2/142 49/18639 0.0408163265306122 5.3575740155217 0.0537071552239264 0.192407187161445 GO:0030544 Hsp70 protein binding 2/142 51/18639 0.0392156862745098 5.14747307373654 0.0576633744828785 0.202904753090758 GO:0001221 transcription coregulator binding 3/142 115/18639 0.0260869565217391 3.42418860992039 0.0577371248632237 0.202904753090758 GO:0004864 protein phosphatase inhibitor activity 2/142 53/18639 0.0377358490566038 4.95322880680308 0.0617176781861547 0.214847389157463 GO:0030246 carbohydrate binding 5/142 280/18639 0.0178571428571429 2.34393863179074 0.0632931758797591 0.218272728033936 GO:0019212 phosphatase inhibitor activity 2/142 56/18639 0.0357142857142857 4.68787726358149 0.0679746639695136 0.229073047537685 GO:0019207 kinase regulator activity 5/142 287/18639 0.0174216027874564 2.28676939686902 0.068795310032306 0.229073047537685 GO:0003680 minor groove of adenine-thymine-rich DNA binding 1/142 10/18639 0.1 13.1260563380282 0.0736420559991168 0.229073047537685 GO:0003796 lysozyme activity 1/142 10/18639 0.1 13.1260563380282 0.0736420559991168 0.229073047537685 GO:0005381 iron ion transmembrane transporter activity 1/142 10/18639 0.1 13.1260563380282 0.0736420559991168 0.229073047537685 GO:0015187 glycine transmembrane transporter activity 1/142 10/18639 0.1 13.1260563380282 0.0736420559991168 0.229073047537685 GO:0015658 branched-chain amino acid transmembrane transporter activity 1/142 10/18639 0.1 13.1260563380282 0.0736420559991168 0.229073047537685 GO:0030957 Tat protein binding 1/142 10/18639 0.1 13.1260563380282 0.0736420559991168 0.229073047537685 GO:0035374 chondroitin sulfate binding 1/142 10/18639 0.1 13.1260563380282 0.0736420559991168 0.229073047537685 GO:0043208 glycosphingolipid binding 1/142 10/18639 0.1 13.1260563380282 0.0736420559991168 0.229073047537685 GO:0004879 nuclear receptor activity 2/142 59/18639 0.0338983050847458 4.4495106230604 0.0744311410335801 0.229073047537685 GO:0098531 ligand-modulated transcription factor activity 2/142 60/18639 0.0333333333333333 4.37535211267606 0.0766255233825 0.229073047537685 GO:0015026 coreceptor activity 2/142 61/18639 0.0327868852459016 4.30362502886169 0.0788402828639121 0.229073047537685 GO:0001851 complement component C3b binding 1/142 11/18639 0.0909090909090909 11.9327784891165 0.0807032416799434 0.229073047537685 GO:0003953 NAD+ nucleosidase activity 1/142 11/18639 0.0909090909090909 11.9327784891165 0.0807032416799434 0.229073047537685 GO:0008432 JUN kinase binding 1/142 11/18639 0.0909090909090909 11.9327784891165 0.0807032416799434 0.229073047537685 GO:0008526 phosphatidylinositol transfer activity 1/142 11/18639 0.0909090909090909 11.9327784891165 0.0807032416799434 0.229073047537685 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water 1/142 11/18639 0.0909090909090909 11.9327784891165 0.0807032416799434 0.229073047537685 GO:0034713 type I transforming growth factor beta receptor binding 1/142 11/18639 0.0909090909090909 11.9327784891165 0.0807032416799434 0.229073047537685 GO:0042608 T cell receptor binding 1/142 11/18639 0.0909090909090909 11.9327784891165 0.0807032416799434 0.229073047537685 GO:0050786 RAGE receptor binding 1/142 11/18639 0.0909090909090909 11.9327784891165 0.0807032416799434 0.229073047537685 GO:0050998 nitric-oxide synthase binding 1/142 11/18639 0.0909090909090909 11.9327784891165 0.0807032416799434 0.229073047537685 GO:0097493 structural molecule activity conferring elasticity 1/142 11/18639 0.0909090909090909 11.9327784891165 0.0807032416799434 0.229073047537685 GO:0051087 protein-folding chaperone binding 3/142 134/18639 0.0223880597014925 2.93866932940929 0.0828068857503914 0.233249930090797 GO:0004859 phospholipase inhibitor activity 1/142 12/18639 0.0833333333333333 10.9383802816901 0.0877109794768862 0.236737793063157 GO:0008179 adenylate cyclase binding 1/142 12/18639 0.0833333333333333 10.9383802816901 0.0877109794768862 0.236737793063157 GO:0010853 cyclase activator activity 1/142 12/18639 0.0833333333333333 10.9383802816901 0.0877109794768862 0.236737793063157 GO:0017166 vinculin binding 1/142 12/18639 0.0833333333333333 10.9383802816901 0.0877109794768862 0.236737793063157 GO:0035259 nuclear glucocorticoid receptor binding 1/142 12/18639 0.0833333333333333 10.9383802816901 0.0877109794768862 0.236737793063157 GO:0120013 lipid transfer activity 2/142 65/18639 0.0307692307692308 4.03878656554713 0.087894519375752 0.236737793063157 GO:0030295 protein kinase activator activity 3/142 139/18639 0.0215827338129496 2.83296179957442 0.0900674280255688 0.238164356302466 GO:0008235 metalloexopeptidase activity 2/142 66/18639 0.0303030303030303 3.97759282970551 0.0902047809836588 0.238164356302466 GO:0005542 folic acid binding 1/142 13/18639 0.0769230769230769 10.0969664138678 0.0946656711027133 0.238164356302466 GO:0008035 high-density lipoprotein particle binding 1/142 13/18639 0.0769230769230769 10.0969664138678 0.0946656711027133 0.238164356302466 GO:0019855 calcium channel inhibitor activity 1/142 13/18639 0.0769230769230769 10.0969664138678 0.0946656711027133 0.238164356302466 GO:0031432 titin binding 1/142 13/18639 0.0769230769230769 10.0969664138678 0.0946656711027133 0.238164356302466 GO:0035325 Toll-like receptor binding 1/142 13/18639 0.0769230769230769 10.0969664138678 0.0946656711027133 0.238164356302466 GO:0039706 co-receptor binding 1/142 13/18639 0.0769230769230769 10.0969664138678 0.0946656711027133 0.238164356302466 GO:0045028 G protein-coupled purinergic nucleotide receptor activity 1/142 13/18639 0.0769230769230769 10.0969664138678 0.0946656711027133 0.238164356302466 GO:1990841 promoter-specific chromatin binding 2/142 68/18639 0.0294117647058824 3.8606048053024 0.0948784834050476 0.238164356302466 GO:0005161 platelet-derived growth factor receptor binding 1/142 14/18639 0.0714285714285714 9.37575452716298 0.101567715272337 0.241796689906403 GO:0019763 immunoglobulin receptor activity 1/142 14/18639 0.0714285714285714 9.37575452716298 0.101567715272337 0.241796689906403 GO:0019992 diacylglycerol binding 1/142 14/18639 0.0714285714285714 9.37575452716298 0.101567715272337 0.241796689906403 GO:0031404 chloride ion binding 1/142 14/18639 0.0714285714285714 9.37575452716298 0.101567715272337 0.241796689906403 GO:0042043 neurexin family protein binding 1/142 14/18639 0.0714285714285714 9.37575452716298 0.101567715272337 0.241796689906403 GO:0043176 amine binding 1/142 14/18639 0.0714285714285714 9.37575452716298 0.101567715272337 0.241796689906403 GO:0044548 S100 protein binding 1/142 14/18639 0.0714285714285714 9.37575452716298 0.101567715272337 0.241796689906403 GO:0061783 peptidoglycan muralytic activity 1/142 14/18639 0.0714285714285714 9.37575452716298 0.101567715272337 0.241796689906403 GO:0019209 kinase activator activity 3/142 148/18639 0.0202702702702703 2.66068709554625 0.103776464293524 0.245471252078913 GO:0043539 protein serine/threonine kinase activator activity 2/142 73/18639 0.0273972602739726 3.59617981863785 0.106854563017723 0.250037877190841 GO:0005041 low-density lipoprotein particle receptor activity 1/142 15/18639 0.0666666666666667 8.75070422535211 0.108417507725026 0.250037877190841 GO:0031005 filamin binding 1/142 15/18639 0.0666666666666667 8.75070422535211 0.108417507725026 0.250037877190841 GO:0120283 protein serine/threonine kinase binding 1/142 15/18639 0.0666666666666667 8.75070422535211 0.108417507725026 0.250037877190841 GO:0019003 GDP binding 2/142 75/18639 0.0266666666666667 3.50028169014085 0.111753705610942 0.250085281293771 GO:0045296 cadherin binding 5/142 334/18639 0.0149700598802395 1.96497849371679 0.112269543237853 0.250085281293771 GO:0005149 interleukin-1 receptor binding 1/142 16/18639 0.0625 8.20378521126761 0.115215441246453 0.250085281293771 GO:0005521 lamin binding 1/142 16/18639 0.0625 8.20378521126761 0.115215441246453 0.250085281293771 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 1/142 16/18639 0.0625 8.20378521126761 0.115215441246453 0.250085281293771 GO:0016722 oxidoreductase activity, acting on metal ions 1/142 16/18639 0.0625 8.20378521126761 0.115215441246453 0.250085281293771 GO:0019841 retinol binding 1/142 16/18639 0.0625 8.20378521126761 0.115215441246453 0.250085281293771 GO:0022858 alanine transmembrane transporter activity 1/142 16/18639 0.0625 8.20378521126761 0.115215441246453 0.250085281293771 GO:0055102 lipase inhibitor activity 1/142 16/18639 0.0625 8.20378521126761 0.115215441246453 0.250085281293771 GO:0061809 NAD+ nucleosidase activity, cyclic ADP-ribose generating 1/142 16/18639 0.0625 8.20378521126761 0.115215441246453 0.250085281293771 GO:0008429 phosphatidylethanolamine binding 1/142 17/18639 0.0588235294117647 7.72120961060481 0.121961905690581 0.255704222726274 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 1/142 17/18639 0.0588235294117647 7.72120961060481 0.121961905690581 0.255704222726274 GO:0030169 low-density lipoprotein particle binding 1/142 17/18639 0.0588235294117647 7.72120961060481 0.121961905690581 0.255704222726274 GO:0036041 long-chain fatty acid binding 1/142 17/18639 0.0588235294117647 7.72120961060481 0.121961905690581 0.255704222726274 GO:0048038 quinone binding 1/142 17/18639 0.0588235294117647 7.72120961060481 0.121961905690581 0.255704222726274 GO:0070492 oligosaccharide binding 1/142 17/18639 0.0588235294117647 7.72120961060481 0.121961905690581 0.255704222726274 GO:0008525 phosphatidylcholine transporter activity 1/142 18/18639 0.0555555555555556 7.29225352112676 0.128657288001393 0.260849116881944 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 1/142 18/18639 0.0555555555555556 7.29225352112676 0.128657288001393 0.260849116881944 GO:0030228 lipoprotein particle receptor activity 1/142 18/18639 0.0555555555555556 7.29225352112676 0.128657288001393 0.260849116881944 GO:0032393 MHC class I receptor activity 1/142 18/18639 0.0555555555555556 7.29225352112676 0.128657288001393 0.260849116881944 GO:0035615 clathrin adaptor activity 1/142 18/18639 0.0555555555555556 7.29225352112676 0.128657288001393 0.260849116881944 GO:1901611 phosphatidylglycerol binding 1/142 18/18639 0.0555555555555556 7.29225352112676 0.128657288001393 0.260849116881944 GO:0019887 protein kinase regulator activity 4/142 255/18639 0.0156862745098039 2.05898922949461 0.13068707683646 0.2635165647686 GO:0016918 retinal binding 1/142 19/18639 0.0526315789473684 6.90845070422535 0.135301972234452 0.268421654594155 GO:0043395 heparan sulfate proteoglycan binding 1/142 19/18639 0.0526315789473684 6.90845070422535 0.135301972234452 0.268421654594155 GO:0046624 sphingolipid transporter activity 1/142 19/18639 0.0526315789473684 6.90845070422535 0.135301972234452 0.268421654594155 GO:0016209 antioxidant activity 2/142 86/18639 0.0232558139534884 3.0525712414019 0.139655599129839 0.271294037846621 GO:0001614 purinergic nucleotide receptor activity 1/142 20/18639 0.05 6.56302816901408 0.141896339578314 0.271294037846621 GO:0016004 phospholipase activator activity 1/142 20/18639 0.05 6.56302816901408 0.141896339578314 0.271294037846621 GO:0016502 nucleotide receptor activity 1/142 20/18639 0.05 6.56302816901408 0.141896339578314 0.271294037846621 GO:0016505 peptidase activator activity involved in apoptotic process 1/142 20/18639 0.05 6.56302816901408 0.141896339578314 0.271294037846621 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 1/142 20/18639 0.05 6.56302816901408 0.141896339578314 0.271294037846621 GO:0042288 MHC class I protein binding 1/142 20/18639 0.05 6.56302816901408 0.141896339578314 0.271294037846621 GO:0003823 antigen binding 3/142 174/18639 0.0172413793103448 2.26311316172899 0.147469361666072 0.276639613791212 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 1/142 21/18639 0.0476190476190476 6.25050301810865 0.148440768375772 0.276639613791212 GO:0001846 opsonin binding 1/142 21/18639 0.0476190476190476 6.25050301810865 0.148440768375772 0.276639613791212 GO:0036122 BMP binding 1/142 21/18639 0.0476190476190476 6.25050301810865 0.148440768375772 0.276639613791212 GO:0140312 cargo adaptor activity 1/142 21/18639 0.0476190476190476 6.25050301810865 0.148440768375772 0.276639613791212 GO:0072341 modified amino acid binding 2/142 91/18639 0.021978021978022 2.88484754681938 0.152793520556906 0.283320648670845 GO:0005319 lipid transporter activity 3/142 178/18639 0.0168539325842697 2.21225668618452 0.154660051120621 0.283965460406981 GO:0061133 endopeptidase activator activity 1/142 22/18639 0.0454545454545455 5.96638924455826 0.154935634144955 0.283965460406981 GO:0043178 alcohol binding 2/142 92/18639 0.0217391304347826 2.85349050826699 0.155449926835258 0.283965460406981 GO:0016410 N-acyltransferase activity 2/142 94/18639 0.0212765957446809 2.79277794426131 0.160789210300315 0.290486357280469 GO:0004602 glutathione peroxidase activity 1/142 23/18639 0.0434782608695652 5.70698101653399 0.16138130960026 0.290486357280469 GO:0005212 structural constituent of eye lens 1/142 23/18639 0.0434782608695652 5.70698101653399 0.16138130960026 0.290486357280469 GO:0005540 hyaluronic acid binding 1/142 24/18639 0.0416666666666667 5.46919014084507 0.167778164673142 0.293412998883362 GO:0035035 histone acetyltransferase binding 1/142 24/18639 0.0416666666666667 5.46919014084507 0.167778164673142 0.293412998883362 GO:0050431 transforming growth factor beta binding 1/142 24/18639 0.0416666666666667 5.46919014084507 0.167778164673142 0.293412998883362 GO:0050699 WW domain binding 1/142 24/18639 0.0416666666666667 5.46919014084507 0.167778164673142 0.293412998883362 GO:0060229 lipase activator activity 1/142 24/18639 0.0416666666666667 5.46919014084507 0.167778164673142 0.293412998883362 GO:0070300 phosphatidic acid binding 1/142 24/18639 0.0416666666666667 5.46919014084507 0.167778164673142 0.293412998883362 GO:0008234 cysteine-type peptidase activity 3/142 187/18639 0.0160427807486631 2.10578443925586 0.171226765694131 0.298031493118558 GO:0001848 complement binding 1/142 25/18639 0.04 5.25042253521127 0.17412656653274 0.298849781630609 GO:0003707 nuclear steroid receptor activity 1/142 25/18639 0.04 5.25042253521127 0.17412656653274 0.298849781630609 GO:0008139 nuclear localization sequence binding 1/142 25/18639 0.04 5.25042253521127 0.17412656653274 0.298849781630609 GO:0005543 phospholipid binding 6/142 497/18639 0.0120724346076459 1.58463456797121 0.179296104383526 0.302625084430666 GO:0005160 transforming growth factor beta receptor binding 1/142 26/18639 0.0384615384615385 5.04848320693391 0.180426879606359 0.302625084430666 GO:0030247 polysaccharide binding 1/142 26/18639 0.0384615384615385 5.04848320693391 0.180426879606359 0.302625084430666 GO:0070006 metalloaminopeptidase activity 1/142 26/18639 0.0384615384615385 5.04848320693391 0.180426879606359 0.302625084430666 GO:0120014 phospholipid transfer activity 1/142 26/18639 0.0384615384615385 5.04848320693391 0.180426879606359 0.302625084430666 GO:0004364 glutathione transferase activity 1/142 27/18639 0.037037037037037 4.86150234741784 0.186679465599799 0.308900102270519 GO:0005044 scavenger receptor activity 1/142 27/18639 0.037037037037037 4.86150234741784 0.186679465599799 0.308900102270519 GO:0005104 fibroblast growth factor receptor binding 1/142 27/18639 0.037037037037037 4.86150234741784 0.186679465599799 0.308900102270519 GO:0004181 metallocarboxypeptidase activity 1/142 29/18639 0.0344827586206897 4.52622632345799 0.19904288968273 0.326430339079677 GO:0051861 glycolipid binding 1/142 29/18639 0.0344827586206897 4.52622632345799 0.19904288968273 0.326430339079677 GO:0001965 G-protein alpha-subunit binding 1/142 30/18639 0.0333333333333333 4.37535211267606 0.205154437757155 0.333488931860749 GO:0048019 receptor antagonist activity 1/142 30/18639 0.0333333333333333 4.37535211267606 0.205154437757155 0.333488931860749 GO:0005200 structural constituent of cytoskeleton 2/142 112/18639 0.0178571428571429 2.34393863179074 0.210091195396609 0.340016013602407 GO:0051059 NF-kappaB binding 1/142 32/18639 0.03125 4.1018926056338 0.217238961091927 0.350048806300965 GO:0030296 protein tyrosine kinase activator activity 1/142 33/18639 0.0303030303030303 3.97759282970551 0.223212630545624 0.356560435806646 GO:0071889 14-3-3 protein binding 1/142 33/18639 0.0303030303030303 3.97759282970551 0.223212630545624 0.356560435806646 GO:0004869 cysteine-type endopeptidase inhibitor activity 1/142 36/18639 0.0277777777777778 3.64612676056338 0.24086338096101 0.3830973602354 GO:0005501 retinoid binding 1/142 38/18639 0.0263157894736842 3.45422535211268 0.252408707727005 0.398029116031047 GO:0019840 isoprenoid binding 1/142 38/18639 0.0263157894736842 3.45422535211268 0.252408707727005 0.398029116031047 GO:0000217 DNA secondary structure binding 1/142 39/18639 0.0256410256410256 3.36565547128927 0.258115818285726 0.403579393845055 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 1/142 39/18639 0.0256410256410256 3.36565547128927 0.258115818285726 0.403579393845055 GO:0016798 hydrolase activity, acting on glycosyl bonds 2/142 130/18639 0.0153846153846154 2.01939328277356 0.260669097818754 0.405851886477301 GO:0031072 heat shock protein binding 2/142 131/18639 0.0152671755725191 2.00397806687453 0.263492212876509 0.407258144278516 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 1/142 40/18639 0.025 3.28151408450704 0.263779665264405 0.407258144278516 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 1/142 41/18639 0.024390243902439 3.20147715561663 0.2694005743204 0.412484696781027 GO:0015175 neutral L-amino acid transmembrane transporter activity 1/142 41/18639 0.024390243902439 3.20147715561663 0.2694005743204 0.412484696781027 GO:0008307 structural constituent of muscle 1/142 42/18639 0.0238095238095238 3.12525150905433 0.274978868677132 0.417560504287497 GO:0048487 beta-tubulin binding 1/142 42/18639 0.0238095238095238 3.12525150905433 0.274978868677132 0.417560504287497 GO:0008200 ion channel inhibitor activity 1/142 43/18639 0.0232558139534884 3.0525712414019 0.280514869142145 0.424221257022343 GO:0001046 core promoter sequence-specific DNA binding 1/142 44/18639 0.0227272727272727 2.98319462227913 0.286008894125034 0.425553556177975 GO:0001223 transcription coactivator binding 1/142 44/18639 0.0227272727272727 2.98319462227913 0.286008894125034 0.425553556177975 GO:0016248 channel inhibitor activity 1/142 44/18639 0.0227272727272727 2.98319462227913 0.286008894125034 0.425553556177975 GO:0030020 extracellular matrix structural constituent conferring tensile strength 1/142 44/18639 0.0227272727272727 2.98319462227913 0.286008894125034 0.425553556177975 GO:0046915 transition metal ion transmembrane transporter activity 1/142 45/18639 0.0222222222222222 2.9169014084507 0.291461259655244 0.43019681925114 GO:0141110 transporter inhibitor activity 1/142 45/18639 0.0222222222222222 2.9169014084507 0.291461259655244 0.43019681925114 GO:0004180 carboxypeptidase activity 1/142 46/18639 0.0217391304347826 2.85349050826699 0.296872279399729 0.434705837692461 GO:0030291 protein serine/threonine kinase inhibitor activity 1/142 46/18639 0.0217391304347826 2.85349050826699 0.296872279399729 0.434705837692461 GO:0140693 molecular condensate scaffold activity 1/142 48/18639 0.0208333333333333 2.73459507042254 0.307571524491991 0.436365260236617 GO:0001222 transcription corepressor binding 1/142 49/18639 0.0204081632653061 2.67878700776085 0.312860365518409 0.436365260236617 GO:0005004 GPI-linked ephrin receptor activity 1/142 49/18639 0.0204081632653061 2.67878700776085 0.312860365518409 0.436365260236617 GO:0005008 hepatocyte growth factor receptor activity 1/142 49/18639 0.0204081632653061 2.67878700776085 0.312860365518409 0.436365260236617 GO:0005009 insulin receptor activity 1/142 49/18639 0.0204081632653061 2.67878700776085 0.312860365518409 0.436365260236617 GO:0005011 macrophage colony-stimulating factor receptor activity 1/142 49/18639 0.0204081632653061 2.67878700776085 0.312860365518409 0.436365260236617 GO:0005018 platelet-derived growth factor alpha-receptor activity 1/142 49/18639 0.0204081632653061 2.67878700776085 0.312860365518409 0.436365260236617 GO:0005020 stem cell factor receptor activity 1/142 49/18639 0.0204081632653061 2.67878700776085 0.312860365518409 0.436365260236617 GO:0008288 boss receptor activity 1/142 49/18639 0.0204081632653061 2.67878700776085 0.312860365518409 0.436365260236617 GO:0036332 placental growth factor receptor activity 1/142 49/18639 0.0204081632653061 2.67878700776085 0.312860365518409 0.436365260236617 GO:0038062 protein tyrosine kinase collagen receptor activity 1/142 49/18639 0.0204081632653061 2.67878700776085 0.312860365518409 0.436365260236617 GO:0060175 brain-derived neurotrophic factor receptor activity 1/142 49/18639 0.0204081632653061 2.67878700776085 0.312860365518409 0.436365260236617 GO:0019842 vitamin binding 2/142 150/18639 0.0133333333333333 1.75014084507042 0.31699156303344 0.436365260236617 GO:0005006 epidermal growth factor receptor activity 1/142 50/18639 0.02 2.62521126760563 0.318109092150813 0.436365260236617 GO:0005007 fibroblast growth factor receptor activity 1/142 50/18639 0.02 2.62521126760563 0.318109092150813 0.436365260236617 GO:0005017 platelet-derived growth factor receptor activity 1/142 50/18639 0.02 2.62521126760563 0.318109092150813 0.436365260236617 GO:0005019 platelet-derived growth factor beta-receptor activity 1/142 50/18639 0.02 2.62521126760563 0.318109092150813 0.436365260236617 GO:0005010 insulin-like growth factor receptor activity 1/142 51/18639 0.0196078431372549 2.57373653686827 0.323318006504171 0.437012250549594 GO:0005021 vascular endothelial growth factor receptor activity 1/142 51/18639 0.0196078431372549 2.57373653686827 0.323318006504171 0.437012250549594 GO:0005030 neurotrophin receptor activity 1/142 51/18639 0.0196078431372549 2.57373653686827 0.323318006504171 0.437012250549594 GO:0005048 signal sequence binding 1/142 51/18639 0.0196078431372549 2.57373653686827 0.323318006504171 0.437012250549594 GO:0005506 iron ion binding 2/142 154/18639 0.012987012987013 1.70468264130236 0.328168116682351 0.439660331284207 GO:0005080 protein kinase C binding 1/142 52/18639 0.0192307692307692 2.52424160346696 0.328487408434256 0.439660331284207 GO:0005003 ephrin receptor activity 1/142 53/18639 0.0188679245283019 2.47661440340154 0.333617595554412 0.439660331284207 GO:0005005 transmembrane-ephrin receptor activity 1/142 53/18639 0.0188679245283019 2.47661440340154 0.333617595554412 0.439660331284207 GO:0005246 calcium channel regulator activity 1/142 53/18639 0.0188679245283019 2.47661440340154 0.333617595554412 0.439660331284207 GO:0038064 collagen receptor activity 1/142 53/18639 0.0188679245283019 2.47661440340154 0.333617595554412 0.439660331284207 GO:0140296 general transcription initiation factor binding 1/142 53/18639 0.0188679245283019 2.47661440340154 0.333617595554412 0.439660331284207 GO:0015485 cholesterol binding 1/142 54/18639 0.0185185185185185 2.43075117370892 0.338708863252209 0.44163805844546 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 1/142 54/18639 0.0185185185185185 2.43075117370892 0.338708863252209 0.44163805844546 GO:0140463 chromatin-protein adaptor activity 1/142 54/18639 0.0185185185185185 2.43075117370892 0.338708863252209 0.44163805844546 GO:0098632 cell-cell adhesion mediator activity 1/142 55/18639 0.0181818181818182 2.3865556978233 0.343761504705973 0.44664787055107 GO:0004601 peroxidase activity 1/142 57/18639 0.0175438596491228 2.30281690140845 0.353752070646757 0.45801583883738 GO:0001786 phosphatidylserine binding 1/142 59/18639 0.0169491525423729 2.2247553115302 0.363591595238773 0.465851731399678 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 1/142 59/18639 0.0169491525423729 2.2247553115302 0.363591595238773 0.465851731399678 GO:0070888 E-box binding 1/142 59/18639 0.0169491525423729 2.2247553115302 0.363591595238773 0.465851731399678 GO:0004714 transmembrane receptor protein tyrosine kinase activity 1/142 60/18639 0.0166666666666667 2.18767605633803 0.368455426965151 0.470450008824016 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 1/142 61/18639 0.0163934426229508 2.15181251443085 0.373282346033505 0.474969605815046 GO:0015179 L-amino acid transmembrane transporter activity 1/142 62/18639 0.0161290322580645 2.11710586097229 0.37807263061006 0.479411686237498 GO:0005507 copper ion binding 1/142 63/18639 0.0158730158730159 2.08350100603622 0.382826556779698 0.483777395382564 GO:0019843 rRNA binding 1/142 65/18639 0.0153846153846154 2.01939328277356 0.392226427923697 0.493964340968752 GO:0016500 protein-hormone receptor activity 1/142 67/18639 0.0149253731343284 1.95911288627286 0.401484127102419 0.502195399663704 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 1/142 67/18639 0.0149253731343284 1.95911288627286 0.401484127102419 0.502195399663704 GO:0031625 ubiquitin protein ligase binding 3/142 302/18639 0.00993377483443709 1.30391288126108 0.405103835908407 0.502806248466265 GO:0005548 phospholipid transporter activity 1/142 68/18639 0.0147058823529412 1.9303024026512 0.406060330739693 0.502806248466265 GO:0032934 sterol binding 1/142 68/18639 0.0147058823529412 1.9303024026512 0.406060330739693 0.502806248466265 GO:0008080 N-acetyltransferase activity 1/142 69/18639 0.0144927536231884 1.90232700551133 0.410601789629089 0.506729298906802 GO:0004521 RNA endonuclease activity 1/142 73/18639 0.0136986301369863 1.79808990931893 0.428425387225228 0.526963226287031 GO:0017022 myosin binding 1/142 76/18639 0.0131578947368421 1.72711267605634 0.441440906817585 0.53937647223738 GO:0098631 cell adhesion mediator activity 1/142 76/18639 0.0131578947368421 1.72711267605634 0.441440906817585 0.53937647223738 GO:0044389 ubiquitin-like protein ligase binding 3/142 322/18639 0.0093167701863354 1.222924503543 0.445566142489808 0.541014296002589 GO:0051540 metal cluster binding 1/142 77/18639 0.012987012987013 1.70468264130236 0.44571367475552 0.541014296002589 GO:0019199 transmembrane receptor protein kinase activity 1/142 78/18639 0.0128205128205128 1.68282773564464 0.449953986046584 0.544370560167834 GO:0015101 organic cation transmembrane transporter activity 1/142 81/18639 0.0123456790123457 1.62050078247261 0.462482618991508 0.557022930026684 GO:0003924 GTPase activity 3/142 331/18639 0.00906344410876133 1.18967277988171 0.463431001404315 0.557022930026684 GO:0005516 calmodulin binding 2/142 207/18639 0.00966183574879227 1.26821800367422 0.469371588523166 0.562331545990417 GO:0004860 protein kinase inhibitor activity 1/142 84/18639 0.0119047619047619 1.56262575452716 0.474727846025009 0.565079274784607 GO:0051117 ATPase binding 1/142 84/18639 0.0119047619047619 1.56262575452716 0.474727846025009 0.565079274784607 GO:0019210 kinase inhibitor activity 1/142 90/18639 0.0111111111111111 1.45845070422535 0.498393405879857 0.591341372249733 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 1/142 91/18639 0.010989010989011 1.44242377340969 0.502233404605668 0.593987584293241 GO:0004867 serine-type endopeptidase inhibitor activity 1/142 95/18639 0.0105263157894737 1.38169014084507 0.517303681957644 0.609856417387766 GO:0016407 acetyltransferase activity 1/142 96/18639 0.0104166666666667 1.36729753521127 0.5209999113128 0.612257857561857 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 2/142 229/18639 0.00873362445414847 1.14638046620333 0.522746613716437 0.612360318924969 GO:0043130 ubiquitin binding 1/142 100/18639 0.01 1.31260563380282 0.53550588356575 0.623769612470846 GO:0046982 protein heterodimerization activity 3/142 369/18639 0.00813008130081301 1.06715905187221 0.535867119656526 0.623769612470846 GO:0015171 amino acid transmembrane transporter activity 1/142 102/18639 0.00980392156862745 1.28686826843413 0.542594434801928 0.629614296987143 GO:0005525 GTP binding 3/142 378/18639 0.00793650793650794 1.04175050301811 0.552213987342145 0.638767903853453 GO:0000149 SNARE binding 1/142 106/18639 0.00943396226415094 1.23830720170077 0.556450873846992 0.639658481151215 GO:0008013 beta-catenin binding 1/142 106/18639 0.00943396226415094 1.23830720170077 0.556450873846992 0.639658481151215 GO:0005496 steroid binding 1/142 108/18639 0.00925925925925926 1.21537558685446 0.563221970846968 0.64543138895196 GO:0035401 histone H3Y41 kinase activity 1/142 115/18639 0.00869565217391304 1.1413962033068 0.586122535174743 0.667528442837902 GO:0140801 histone H2AXY142 kinase activity 1/142 115/18639 0.00869565217391304 1.1413962033068 0.586122535174743 0.667528442837902 GO:0019001 guanyl nucleotide binding 3/142 400/18639 0.0075 0.984454225352113 0.59072005811208 0.668637120991895 GO:0032561 guanyl ribonucleotide binding 3/142 400/18639 0.0075 0.984454225352113 0.59072005811208 0.668637120991895 GO:0032182 ubiquitin-like protein binding 1/142 120/18639 0.00833333333333333 1.09383802816901 0.601746211344856 0.679034715554286 GO:0004540 RNA nuclease activity 1/142 121/18639 0.00826446280991736 1.08479804446514 0.604799941999266 0.680102577288982 GO:0008528 G protein-coupled peptide receptor activity 1/142 122/18639 0.00819672131147541 1.07590625721542 0.607830420897425 0.680102577288982 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 2/142 268/18639 0.00746268656716418 0.979556443136431 0.608221817087708 0.680102577288982 GO:0005096 GTPase activator activity 2/142 271/18639 0.00738007380073801 0.968712644872928 0.614297089362203 0.684820622279918 GO:0004519 endonuclease activity 1/142 127/18639 0.0078740157480315 1.03354774315182 0.622640145979646 0.692030764658101 GO:0001653 peptide receptor activity 1/142 128/18639 0.0078125 1.02547315140845 0.625534760244496 0.693160139730387 GO:0001217 DNA-binding transcription repressor activity 2/142 278/18639 0.00719424460431655 0.944320599858142 0.628194294169091 0.694023037570043 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 1/142 130/18639 0.00769230769230769 1.00969664138678 0.631258009903738 0.695325987028297 GO:0005179 hormone activity 1/142 132/18639 0.00757575757575758 0.994398207426377 0.636894393241247 0.69944652114887 GO:0035091 phosphatidylinositol binding 2/142 284/18639 0.00704225352112676 0.924370164649871 0.639796932816653 0.700549163825949 GO:0015297 antiporter activity 1/142 135/18639 0.00740740740740741 0.972300469483568 0.645188952468906 0.7043630871628 GO:0044325 transmembrane transporter binding 1/142 136/18639 0.00735294117647059 0.965151201325601 0.647911778276808 0.70524910378803 GO:0016922 nuclear receptor binding 1/142 137/18639 0.0072992700729927 0.958106302045852 0.65061385510136 0.706107389801182 GO:0004713 protein tyrosine kinase activity 1/142 140/18639 0.00714285714285714 0.937575452716298 0.658597155809444 0.712675514644237 GO:0019903 protein phosphatase binding 1/142 144/18639 0.00694444444444444 0.911531690140845 0.668960462014395 0.721773130068163 GO:0099106 ion channel regulator activity 1/142 160/18639 0.00625 0.820378521126761 0.707381542635641 0.761002300969538 GO:0016247 channel regulator activity 1/142 168/18639 0.00595238095238095 0.781312877263581 0.724897095709783 0.777578570688691 GO:0141108 transporter regulator activity 1/142 170/18639 0.00588235294117647 0.772120961060481 0.729110782327995 0.779831532402986 GO:0003712 transcription coregulator activity 3/142 495/18639 0.00606060606060606 0.795518565941101 0.731406452264854 0.780025956317143 GO:0003735 structural constituent of ribosome 1/142 175/18639 0.00571428571428571 0.750060362173038 0.739366708034866 0.786242983472235 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 1/142 181/18639 0.00552486187845304 0.725196482763987 0.751166024291929 0.796495008516442 GO:1901981 phosphatidylinositol phosphate binding 1/142 185/18639 0.00540540540540541 0.709516558812334 0.758735981765615 0.802216553786567 GO:0046943 carboxylic acid transmembrane transporter activity 1/142 188/18639 0.00531914893617021 0.698194486065328 0.764262974512355 0.804962599873707 GO:0005342 organic acid transmembrane transporter activity 1/142 189/18639 0.00529100529100529 0.694500335345406 0.766077220765634 0.804962599873707 GO:0019902 phosphatase binding 1/142 190/18639 0.00526315789473684 0.690845070422535 0.767877602047547 0.804962599873707 GO:0016829 lyase activity 1/142 200/18639 0.005 0.656302816901408 0.785141600798327 0.820728755508733 GO:0003714 transcription corepressor activity 1/142 204/18639 0.00490196078431373 0.643434134217067 0.791684620668074 0.825230579170959 GO:0015631 tubulin binding 2/142 385/18639 0.00519480519480519 0.681873056520944 0.794918399648863 0.826267294282903 GO:0004518 nuclease activity 1/142 209/18639 0.00478468899521531 0.628040973111396 0.799585810354706 0.828784168597996 GO:0003713 transcription coactivator activity 1/142 256/18639 0.00390625 0.512736575704225 0.860731916441068 0.889664081699592 GO:0008514 organic anion transmembrane transporter activity 1/142 269/18639 0.00371747211895911 0.487957484685062 0.874091057105355 0.900948603552726 GO:0008017 microtubule binding 1/142 276/18639 0.0036231884057971 0.475581751377832 0.880749075561237 0.905282475994697 GO:0030695 GTPase regulator activity 2/142 489/18639 0.00408997955010225 0.536853019960252 0.890248775884457 0.908153646971198 GO:0015291 secondary active transmembrane transporter activity 1/142 287/18639 0.00348432055749129 0.457353879373804 0.890512150360758 0.908153646971198 GO:0060589 nucleoside-triphosphatase regulator activity 2/142 490/18639 0.00408163265306122 0.53575740155217 0.890925800009684 0.908153646971198 GO:0141003 histone H2AX kinase activity 1/142 354/18639 0.00282485875706215 0.3707925519217 0.934996692114273 0.948246855849527 GO:0140996 histone H3 kinase activity 1/142 357/18639 0.00280112044817927 0.367676648124038 0.936499476226059 0.948246855849527 GO:0035173 histone kinase activity 1/142 360/18639 0.00277777777777778 0.364612676056338 0.937967757141131 0.948246855849527 GO:0140098 catalytic activity, acting on RNA 1/142 387/18639 0.00258397932816537 0.339174582377989 0.949753747963489 0.957538614750075 GO:0046873 metal ion transmembrane transporter activity 1/142 450/18639 0.00222222222222222 0.29169014084507 0.969306822860706 0.973584082332877 GO:0022804 active transmembrane transporter activity 1/142 457/18639 0.00218818380743982 0.287222239344161 0.970945643085362 0.973584082332877 GO:0016755 aminoacyltransferase activity 1/142 496/18639 0.00201612903225806 0.264638232621536 0.978606981779305 0.978606981779305