category subcategory ID Description GeneRatio BgRatio FoldEnrichment geneName zScore Human Diseases Cardiovascular disease hsa05415 Diabetic cardiomyopathy 7/28 205/9376 11.4341463414634 MT-CYB/MT-CO3/MT-ND5/MT-CO1/MT-ND4/MT-ND1/REN 8.26667396124629 Metabolism Energy metabolism hsa00190 Oxidative phosphorylation 6/28 138/9376 14.5590062111801 MT-CYB/MT-CO3/MT-ND5/MT-CO1/MT-ND4/MT-ND1 8.78180371735216 Human Diseases Cancer: overview hsa05208 Chemical carcinogenesis - reactive oxygen species 6/28 227/9376 8.8508495909377 MT-CYB/MT-CO3/MT-ND5/MT-CO1/MT-ND4/MT-ND1 6.55311929258004 Organismal Systems Environmental adaptation hsa04714 Thermogenesis 6/28 235/9376 8.54954407294833 MT-CYB/MT-CO3/MT-ND5/MT-CO1/MT-ND4/MT-ND1 6.41450434238709 Human Diseases Neurodegenerative disease hsa05010 Alzheimer disease 7/28 388/9376 6.04123711340206 MT-CYB/MT-CO3/DKK1/MT-ND5/MT-CO1/MT-ND4/MT-ND1 5.55043163500958 Human Diseases Neurodegenerative disease hsa05012 Parkinson disease 6/28 268/9376 7.49680170575693 MT-CYB/MT-CO3/MT-ND5/MT-CO1/MT-ND4/MT-ND1 5.90555610139922 Organismal Systems Immune system hsa04610 Complement and coagulation cascades 4/28 88/9376 15.2207792207792 TFPI/SERPING1/VWF/F8 7.3351488068726 Human Diseases Neurodegenerative disease hsa05020 Prion disease 6/28 275/9376 7.30597402597403 MT-CYB/MT-CO3/MT-ND5/MT-CO1/MT-ND4/MT-ND1 5.80870430844189 Human Diseases Neurodegenerative disease hsa05016 Huntington disease 6/28 308/9376 6.52319109461967 MT-CYB/MT-CO3/MT-ND5/MT-CO1/MT-ND4/MT-ND1 5.39405007672521 Human Diseases Neurodegenerative disease hsa05022 Pathways of neurodegeneration - multiple diseases 7/28 480/9376 4.88333333333333 MT-CYB/MT-CO3/DKK1/MT-ND5/MT-CO1/MT-ND4/MT-ND1 4.78005841780556 Human Diseases Neurodegenerative disease hsa05014 Amyotrophic lateral sclerosis 6/28 368/9376 5.45962732919255 MT-CYB/MT-CO3/MT-ND5/MT-CO1/MT-ND4/MT-ND1 4.77654188964972 NA NA hsa03273 Virion - Lassa virus and SFTS virus 2/28 17/9376 39.3949579831933 CLEC4M/MYH11 8.6714003118839 Organismal Systems Circulatory system hsa04260 Cardiac muscle contraction 3/28 87/9376 11.5467980295567 MT-CYB/MT-CO3/MT-CO1 5.4088019096563 Cellular Processes Cell motility hsa04820 Cytoskeleton in muscle cells 4/28 233/9376 5.74862047823421 DCN/VCAN/LMOD1/MYH11 4.01704191854156 Organismal Systems Nervous system hsa04723 Retrograde endocannabinoid signaling 3/28 149/9376 6.74209012464046 MT-ND5/MT-ND4/MT-ND1 3.86667954145257 Human Diseases Endocrine and metabolic disease hsa04932 Non-alcoholic fatty liver disease 3/28 157/9376 6.39854413102821 MT-CYB/MT-CO3/MT-CO1 3.73327409392137 Organismal Systems Endocrine system hsa03320 PPAR signaling pathway 2/28 76/9376 8.81203007518797 FABP5/PLIN5 3.74226493652571 Environmental Information Processing Signaling molecules and interaction hsa04512 ECM-receptor interaction 2/28 89/9376 7.52487961476726 VWF/SPP1 3.38481616051684 Genetic Information Processing Information processing in viruses hsa03265 Virion - Ebolavirus, Lyssavirus and Morbillivirus 1/28 12/9376 27.9047619047619 CLEC4M 5.10380855585106 Organismal Systems Endocrine system hsa04614 Renin-angiotensin system 1/28 23/9376 14.5590062111801 REN 3.56304750353892 NA NA hsa04518 Integrin signaling 2/28 154/9376 4.34879406307978 VWF/SPP1 2.29319794829074 Cellular Processes Cell growth and death hsa04216 Ferroptosis 1/28 42/9376 7.97278911564626 FTH1 2.47857793735949 Cellular Processes Cellular community - eukaryotes hsa04510 Focal adhesion 2/28 203/9376 3.2990851513019 VWF/SPP1 1.81239427126045 Human Diseases Cancer: overview hsa05205 Proteoglycans in cancer 2/28 204/9376 3.28291316526611 TIMP3/DCN 1.80417123917315 Metabolism Metabolism of cofactors and vitamins hsa00860 Porphyrin metabolism 1/28 46/9376 7.27950310559006 FTH1 2.33651554917664 Genetic Information Processing Translation hsa03010 Ribosome 2/28 222/9376 3.01673101673102 MT-RNR2/RPL10 1.6642720239924 Cellular Processes Cell motility hsa04810 Regulation of actin cytoskeleton 2/28 232/9376 2.88669950738916 TMSB4X/MYH11 1.59251643062077 Human Diseases Infectious disease: viral hsa05171 Coronavirus disease - COVID-19 2/28 238/9376 2.81392557022809 VWF/RPL10 1.55127097462544 Organismal Systems Digestive system hsa04978 Mineral absorption 1/28 61/9376 5.48946135831382 FTH1 1.92518747587651 Organismal Systems Endocrine system hsa04929 GnRH secretion 1/28 65/9376 5.15164835164835 SPP1 1.83816451626235 Organismal Systems Endocrine system hsa04924 Renin secretion 1/28 69/9376 4.85300207039337 REN 1.75802170547438 Human Diseases Infectious disease: bacterial hsa05133 Pertussis 1/28 78/9376 4.29304029304029 SERPING1 1.59828740511199 NA NA hsa04517 IgSF CAM signaling 2/28 299/9376 2.23984710941233 CLEC4M/MYH11 1.192443641973 Human Diseases Cancer: overview hsa05206 MicroRNAs in cancer 2/28 323/9376 2.0734188412207 TIMP3/STMN1 1.0744334409764 Environmental Information Processing Signaling molecules and interaction hsa04061 Viral protein interaction with cytokine and cytokine receptor 1/28 100/9376 3.34857142857143 CXCL14 1.29219693091837 Human Diseases Infectious disease: viral hsa05165 Human papillomavirus infection 2/28 333/9376 2.01115401115401 VWF/SPP1 1.02822571823441 Organismal Systems Immune system hsa04625 C-type lectin receptor signaling pathway 1/28 105/9376 3.1891156462585 CLEC4M 1.23454056871824 Organismal Systems Immune system hsa04620 Toll-like receptor signaling pathway 1/28 109/9376 3.07208387942333 SPP1 1.19084791728458 Environmental Information Processing Signal transduction hsa04350 TGF-beta signaling pathway 1/28 110/9376 3.04415584415584 DCN 1.18023774466725 Environmental Information Processing Signal transduction hsa04151 PI3K-Akt signaling pathway 2/28 362/9376 1.85003946329913 VWF/SPP1 0.902692634429901 Organismal Systems Immune system hsa04611 Platelet activation 1/28 126/9376 2.65759637188209 VWF 1.02517615381285 Organismal Systems Circulatory system hsa04270 Vascular smooth muscle contraction 1/28 134/9376 2.49893390191898 MYH11 0.956438834167306 Human Diseases Infectious disease: viral hsa05162 Measles 1/28 136/9376 2.46218487394958 CLEC4M 0.940028579300301 Environmental Information Processing Signal transduction hsa04371 Apelin signaling pathway 1/28 140/9376 2.39183673469388 SPP1 0.908062314423247 Cellular Processes Transport and catabolism hsa04145 Phagosome 1/28 155/9376 2.16036866359447 CLEC4M 0.797219902012292 Environmental Information Processing Signaling molecules and interaction hsa04514 Cell adhesion molecule (CAM) interaction 1/28 160/9376 2.09285714285714 VCAN 0.763057834011308 Cellular Processes Cell growth and death hsa04217 Necroptosis 1/28 168/9376 1.99319727891156 FTH1 0.710907029523862 Cellular Processes Cellular community - eukaryotes hsa04530 Tight junction 1/28 170/9376 1.96974789915966 MYH11 0.698317820219578 Environmental Information Processing Signal transduction hsa04310 Wnt signaling pathway 1/28 178/9376 1.88121990369181 DKK1 0.649610294052663 Human Diseases Infectious disease: bacterial hsa05152 Tuberculosis 1/28 181/9376 1.85003946329913 CLEC4M 0.63198651418772 Organismal Systems Immune system hsa04062 Chemokine signaling pathway 1/28 193/9376 1.73501110288675 CXCL14 0.564658101780911 Cellular Processes Cell motility hsa04814 Motor proteins 1/28 194/9376 1.7260677466863 MYH11 0.559261171074678 Organismal Systems Immune system hsa04613 Neutrophil extracellular trap formation 1/28 195/9376 1.71721611721612 VWF 0.55389526735576 NA NA hsa04082 Neuroactive ligand signaling 1/28 199/9376 1.6826992103374 P2RY14 0.532734564005087 Human Diseases Infectious disease: bacterial hsa05130 Pathogenic Escherichia coli infection 1/28 200/9376 1.67428571428571 MYH11 0.527518331323847 Environmental Information Processing Signaling molecules and interaction hsa04060 Cytokine-cytokine receptor interaction 1/28 298/9376 1.12368168744008 CXCL14 0.118747300825402 Environmental Information Processing Signal transduction hsa04010 MAPK signaling pathway 1/28 300/9376 1.11619047619048 STMN1 0.111941009049213 Environmental Information Processing Signaling molecules and interaction hsa04080 Neuroactive ligand-receptor interaction 1/28 370/9376 0.905019305019305 P2RY14 -0.102017701800131