category subcategory ID Description GeneRatio BgRatio FoldEnrichment geneName zScore Genetic Information Processing Translation hsa03010 Ribosome 16/36 222/9376 18.7707707707708 MT-RNR2/RPS18/RPL12/RPS27/RPL32/RPL10/RPL3/RPS15A/RPS6/RPL7A/RPL15/RPL29/RPL36/RPS8/RPS7/RPL6 16.6356873050775 Human Diseases Infectious disease: viral hsa05171 Coronavirus disease - COVID-19 15/36 238/9376 16.4145658263305 RPS18/RPL12/RPS27/RPL32/RPL10/RPL3/RPS15A/RPS6/RPL7A/RPL15/RPL29/RPL36/RPS8/RPS7/RPL6 14.954009383824 Organismal Systems Environmental adaptation hsa04714 Thermogenesis 11/36 235/9376 12.1910165484634 MT-CYB/MT-CO1/MT-ND1/MT-CO3/MT-ND4L/MT-ND5/MT-ATP6/MT-ND3/RPS6/ACTB/COX6C 10.7862396452604 Metabolism Energy metabolism hsa00190 Oxidative phosphorylation 9/36 138/9376 16.9855072463768 MT-CYB/MT-CO1/MT-ND1/MT-CO3/MT-ND4L/MT-ND5/MT-ATP6/MT-ND3/COX6C 11.7446596661269 Human Diseases Cardiovascular disease hsa05415 Diabetic cardiomyopathy 9/36 205/9376 11.4341463414634 MT-CYB/MT-CO1/MT-ND1/MT-CO3/MT-ND4L/MT-ND5/MT-ATP6/MT-ND3/COX6C 9.37754070121164 Human Diseases Cancer: overview hsa05208 Chemical carcinogenesis - reactive oxygen species 9/36 227/9376 10.3259911894273 MT-CYB/MT-CO1/MT-ND1/MT-CO3/MT-ND4L/MT-ND5/MT-ATP6/MT-ND3/COX6C 8.83048518186849 Human Diseases Neurodegenerative disease hsa05012 Parkinson disease 9/36 268/9376 8.74626865671642 MT-CYB/MT-CO1/MT-ND1/MT-CO3/MT-ND4L/MT-ND5/MT-ATP6/MT-ND3/COX6C 7.98751876881631 Human Diseases Neurodegenerative disease hsa05020 Prion disease 9/36 275/9376 8.52363636363636 MT-CYB/MT-CO1/MT-ND1/MT-CO3/MT-ND4L/MT-ND5/MT-ATP6/MT-ND3/COX6C 7.86163790553018 Human Diseases Neurodegenerative disease hsa05014 Amyotrophic lateral sclerosis 10/36 368/9376 7.07729468599034 MT-CYB/MT-CO1/MT-ND1/MT-CO3/MT-ND4L/MT-ND5/MT-ATP6/MT-ND3/ACTB/COX6C 7.38386022017327 Human Diseases Neurodegenerative disease hsa05016 Huntington disease 9/36 308/9376 7.61038961038961 MT-CYB/MT-CO1/MT-ND1/MT-CO3/MT-ND4L/MT-ND5/MT-ATP6/MT-ND3/COX6C 7.32335538888421 Human Diseases Neurodegenerative disease hsa05010 Alzheimer disease 9/36 388/9376 6.04123711340206 MT-CYB/MT-CO1/MT-ND1/MT-CO3/MT-ND4L/MT-ND5/MT-ATP6/MT-ND3/COX6C 6.29629265779679 Human Diseases Neurodegenerative disease hsa05022 Pathways of neurodegeneration - multiple diseases 9/36 480/9376 4.88333333333333 MT-CYB/MT-CO1/MT-ND1/MT-CO3/MT-ND4L/MT-ND5/MT-ATP6/MT-ND3/COX6C 5.4223975177053 Organismal Systems Circulatory system hsa04260 Cardiac muscle contraction 4/36 87/9376 11.9744572158365 MT-CYB/MT-CO1/MT-CO3/COX6C 6.38442287640345 Organismal Systems Nervous system hsa04723 Retrograde endocannabinoid signaling 4/36 149/9376 6.99179716629381 MT-ND1/MT-ND4L/MT-ND5/MT-ND3 4.57702650748756 Human Diseases Endocrine and metabolic disease hsa04932 Non-alcoholic fatty liver disease 4/36 157/9376 6.63552724699221 MT-CYB/MT-CO1/MT-CO3/COX6C 4.42085146149139 Environmental Information Processing Signaling molecules and interaction hsa04061 Viral protein interaction with cytokine and cytokine receptor 2/36 100/9376 5.20888888888889 CXCL14/CCL21 2.62694234618023 Environmental Information Processing Signaling molecules and interaction hsa04060 Cytokine-cytokine receptor interaction 3/36 298/9376 2.62192393736018 CXCL14/CCL21/TNFRSF18 1.7664728900937 Organismal Systems Immune system hsa04062 Chemokine signaling pathway 2/36 193/9376 2.69890616004606 CXCL14/CCL21 1.48053679062144 Human Diseases Infectious disease: bacterial hsa05110 Vibrio cholerae infection 1/36 51/9376 5.10675381263617 ACTB 1.82567213606213 Human Diseases Cancer: overview hsa05205 Proteoglycans in cancer 2/36 204/9376 2.55337690631808 RPS6/ACTB 1.39259026686932 Cellular Processes Cell motility hsa04810 Regulation of actin cytoskeleton 2/36 232/9376 2.24521072796935 TMSB4X/ACTB 1.19229078630943 Human Diseases Cardiovascular disease hsa05416 Viral myocarditis 1/36 70/9376 3.72063492063492 ACTB 1.41840813859346 Organismal Systems Digestive system hsa04971 Gastric acid secretion 1/36 76/9376 3.42690058479532 ACTB 1.31880552726197 Genetic Information Processing Folding, sorting and degradation hsa03018 RNA degradation 1/36 78/9376 3.33903133903134 PABPC1 1.28781067734868 Human Diseases Infectious disease: bacterial hsa05100 Bacterial invasion of epithelial cells 1/36 78/9376 3.33903133903134 ACTB 1.28781067734868 Human Diseases Drug resistance: antineoplastic hsa01521 EGFR tyrosine kinase inhibitor resistance 1/36 80/9376 3.25555555555556 RPS6 1.25780673228091 Human Diseases Cardiovascular disease hsa05412 Arrhythmogenic right ventricular cardiomyopathy 1/36 86/9376 3.02842377260982 ACTB 1.17317692090779 Organismal Systems Nervous system hsa04727 GABAergic synapse 1/36 89/9376 2.92634207240949 PLCL1 1.13358513170293 Cellular Processes Cellular community - eukaryotes hsa04520 Adherens junction 1/36 93/9376 2.80047789725209 ACTB 1.08329950285231 Organismal Systems Digestive system hsa04970 Salivary secretion 1/36 93/9376 2.80047789725209 CST3 1.08329950285231 Human Diseases Cardiovascular disease hsa05410 Hypertrophic cardiomyopathy 1/36 99/9376 2.6307519640853 ACTB 1.01266355360306 Genetic Information Processing Translation hsa03015 mRNA surveillance pathway 1/36 103/9376 2.52858683926645 PABPC1 0.968416207078219 Environmental Information Processing Signal transduction hsa04064 NF-kappa B signaling pathway 1/36 105/9376 2.48042328042328 CCL21 0.947067024666948 Human Diseases Cardiovascular disease hsa05414 Dilated cardiomyopathy 1/36 105/9376 2.48042328042328 ACTB 0.947067024666948 Environmental Information Processing Signal transduction hsa04066 HIF-1 signaling pathway 1/36 110/9376 2.36767676767677 RPS6 0.895771240351504 Organismal Systems Immune system hsa04670 Leukocyte transendothelial migration 1/36 116/9376 2.24521072796935 ACTB 0.837779646939483 Genetic Information Processing Chromosome hsa03082 ATP-dependent chromatin remodeling 1/36 117/9376 2.22602089268756 ACTB 0.828461270219553 Organismal Systems Endocrine system hsa04919 Thyroid hormone signaling pathway 1/36 122/9376 2.13479052823315 ACTB 0.783239029169927 Organismal Systems Immune system hsa04611 Platelet activation 1/36 126/9376 2.06701940035273 ACTB 0.748600602678128 Organismal Systems Immune system hsa04650 Natural killer cell mediated cytotoxicity 1/36 133/9376 1.95822890559733 HCST 0.690958656150376 Cellular Processes Cell growth and death hsa04210 Apoptosis 1/36 137/9376 1.90105433901054 ACTB 0.659572033478088 Organismal Systems Endocrine system hsa04910 Insulin signaling pathway 1/36 138/9376 1.88727858293076 RPS6 0.65188954125475 Human Diseases Infectious disease: bacterial hsa05135 Yersinia infection 1/36 138/9376 1.88727858293076 ACTB 0.65188954125475 Environmental Information Processing Signal transduction hsa04371 Apelin signaling pathway 1/36 140/9376 1.86031746031746 RPS6 0.636713771407471 Human Diseases Cardiovascular disease hsa05418 Fluid shear stress and atherosclerosis 1/36 142/9376 1.83411580594679 ACTB 0.621783278436553 NA NA hsa04518 Integrin signaling 1/36 154/9376 1.69119769119769 ACTB 0.536924882473679 Organismal Systems Endocrine system hsa04921 Oxytocin signaling pathway 1/36 154/9376 1.69119769119769 ACTB 0.536924882473679 Cellular Processes Transport and catabolism hsa04145 Phagosome 1/36 155/9376 1.68028673835125 ACTB 0.530190929260985 Environmental Information Processing Signal transduction hsa04390 Hippo signaling pathway 1/36 157/9376 1.65888181174805 ACTB 0.516867099164697 Environmental Information Processing Signal transduction hsa04150 mTOR signaling pathway 1/36 158/9376 1.64838255977496 RPS6 0.510275793480595 Cellular Processes Cellular community - eukaryotes hsa04530 Tight junction 1/36 170/9376 1.53202614379085 ACTB 0.434595674946782 Human Diseases Cancer: specific types hsa05225 Hepatocellular carcinoma 1/36 170/9376 1.53202614379085 ACTB 0.434595674946782 Human Diseases Infectious disease: viral hsa05164 Influenza A 1/36 173/9376 1.50545921644188 ACTB 0.416589107970435 Organismal Systems Development and regeneration hsa04360 Axon guidance 1/36 184/9376 1.41545893719807 SEMA5A 0.353342160278552 Organismal Systems Immune system hsa04621 NOD-like receptor signaling pathway 1/36 187/9376 1.39275103980986 TXNIP 0.336796423872414 Cellular Processes Cell motility hsa04814 Motor proteins 1/36 194/9376 1.34249713631157 ACTB 0.299262717873989 Organismal Systems Immune system hsa04613 Neutrophil extracellular trap formation 1/36 195/9376 1.33561253561254 ACTB 0.294018011768177 Human Diseases Infectious disease: bacterial hsa05130 Pathogenic Escherichia coli infection 1/36 200/9376 1.30222222222222 ACTB 0.268211960380584 Cellular Processes Cellular community - eukaryotes hsa04510 Focal adhesion 1/36 203/9376 1.28297755883963 ACTB 0.253050831335005 Environmental Information Processing Signal transduction hsa04015 Rap1 signaling pathway 1/36 212/9376 1.22851153039832 ACTB 0.208928150408146 Cellular Processes Cell motility hsa04820 Cytoskeleton in muscle cells 1/36 233/9376 1.11778731521221 ACTB 0.113030480518917 Human Diseases Infectious disease: bacterial hsa05132 Salmonella infection 1/36 248/9376 1.05017921146953 ACTB 0.0497193345758868 Human Diseases Infectious disease: bacterial hsa05131 Shigellosis 1/36 253/9376 1.02942468159859 ACTB 0.0294555167207152 NA NA hsa04517 IgSF CAM signaling 1/36 299/9376 0.871051653660349 ACTB -0.140683658580692 Environmental Information Processing Signal transduction hsa04151 PI3K-Akt signaling pathway 1/36 362/9376 0.719459791282996 RPS6 -0.337951263614796 NA NA hsa04519 Cadherin signaling 1/36 404/9376 0.644664466446645 ACTB -0.453260777773512