ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0005201 extracellular matrix structural constituent 17/157 168/18639 0.101190476190476 12.0133075523203 6.2143471920737e-14 2.52923930717399e-11 GO:0008201 heparin binding 16/157 172/18639 0.0930232558139535 11.04369723004 1.30873897184059e-12 2.6632838076956e-10 GO:0005539 glycosaminoglycan binding 18/157 242/18639 0.0743801652892562 8.83039427277991 2.24087792853262e-12 3.04012438970926e-10 GO:0005518 collagen binding 10/157 72/18639 0.138888888888889 16.4888535031847 4.61644573618861e-10 4.69723353657191e-08 GO:1901681 sulfur compound binding 16/157 275/18639 0.0581818181818182 6.90733063115229 1.49836304236106e-09 1.2196675164819e-07 GO:0005178 integrin binding 11/157 161/18639 0.0683229813664596 8.11128694069708 1.19821163793208e-07 8.1278689439726e-06 GO:0061134 peptidase regulator activity 12/157 226/18639 0.0530973451327434 6.30370328617327 4.89241073853527e-07 2.84458738654837e-05 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 7/157 68/18639 0.102941176470588 12.2211502435369 1.65786169238635e-06 8.43437136001555e-05 GO:0008237 metallopeptidase activity 10/157 184/18639 0.0543478260869565 6.45216006646358 3.67929210310573e-06 0.000166385765107115 GO:0004222 metalloendopeptidase activity 8/157 110/18639 0.0727272727272727 8.63416328894036 4.19681046315002e-06 0.000170810185850206 GO:0001968 fibronectin binding 5/157 30/18639 0.166666666666667 19.7866242038217 4.78190200560265e-06 0.000176930374207298 GO:0004866 endopeptidase inhibitor activity 9/157 161/18639 0.0559006211180124 6.63650749693397 9.09645494953806e-06 0.000308521430371832 GO:0030414 peptidase inhibitor activity 9/157 169/18639 0.0532544378698225 6.32235329589568 1.34392215573072e-05 0.00042075101337108 GO:0050840 extracellular matrix binding 6/157 67/18639 0.0895522388059701 10.6316189751878 2.11958467703008e-05 0.000616193545393745 GO:0061135 endopeptidase regulator activity 9/157 184/18639 0.0489130434782609 5.80694405981723 2.64275587518996e-05 0.000717067760801544 GO:0009055 electron transfer activity 7/157 116/18639 0.0603448275862069 7.16412255655612 5.69119007936091e-05 0.00143478549396035 GO:0043548 phosphatidylinositol 3-kinase binding 4/157 26/18639 0.153846153846154 18.2645761881431 6.26843025977056e-05 0.00143478549396035 GO:0022853 active monoatomic ion transmembrane transporter activity 7/157 118/18639 0.0593220338983051 7.04269675051279 6.34548867107773e-05 0.00143478549396035 GO:0019838 growth factor binding 7/157 136/18639 0.0514705882352941 6.11057512176845 0.000154843515201902 0.00320726018792929 GO:0031994 insulin-like growth factor I binding 3/157 13/18639 0.230769230769231 27.3968642822146 0.000157604923239769 0.00320726018792929 GO:0004857 enzyme inhibitor activity 12/157 416/18639 0.0288461538461538 3.42460803527683 0.000215811860454758 0.0041826393907184 GO:0005159 insulin-like growth factor receptor binding 3/157 16/18639 0.1875 22.2599522292994 0.000302918234279524 0.00560398733417119 GO:0003779 actin binding 12/157 443/18639 0.0270880361173815 3.21588474644505 0.000381667243690577 0.00652752181011194 GO:0008137 NADH dehydrogenase (ubiquinone) activity 4/157 41/18639 0.0975609756097561 11.5824141680907 0.000384915291013972 0.00652752181011194 GO:0008083 growth factor activity 7/157 162/18639 0.0432098765432099 5.12986553432413 0.000450677134224032 0.00730316850743471 GO:0003954 NADH dehydrogenase activity 4/157 44/18639 0.0909090909090909 10.7927041111754 0.000505964177604534 0.00730316850743471 GO:0019199 transmembrane receptor protein kinase activity 5/157 78/18639 0.0641025641025641 7.61024007839294 0.000511896653106524 0.00730316850743471 GO:0005520 insulin-like growth factor binding 3/157 19/18639 0.157894736842105 18.7452229299363 0.00051452217029018 0.00730316850743471 GO:0015399 primary active transmembrane transporter activity 7/157 166/18639 0.0421686746987952 5.00625431662958 0.000521532548968548 0.00730316850743471 GO:0008009 chemokine activity 4/157 45/18639 0.0888888888888889 10.5528662420382 0.000551713967972757 0.00730316850743471 GO:0004175 endopeptidase activity 11/157 405/18639 0.0271604938271605 3.22448690728946 0.000654316975842379 0.00730316850743471 GO:0005004 GPI-linked ephrin receptor activity 4/157 49/18639 0.0816326530612245 9.6914077733004 0.000764352038134658 0.00730316850743471 GO:0005008 hepatocyte growth factor receptor activity 4/157 49/18639 0.0816326530612245 9.6914077733004 0.000764352038134658 0.00730316850743471 GO:0005009 insulin receptor activity 4/157 49/18639 0.0816326530612245 9.6914077733004 0.000764352038134658 0.00730316850743471 GO:0005011 macrophage colony-stimulating factor receptor activity 4/157 49/18639 0.0816326530612245 9.6914077733004 0.000764352038134658 0.00730316850743471 GO:0005018 platelet-derived growth factor alpha-receptor activity 4/157 49/18639 0.0816326530612245 9.6914077733004 0.000764352038134658 0.00730316850743471 GO:0005020 stem cell factor receptor activity 4/157 49/18639 0.0816326530612245 9.6914077733004 0.000764352038134658 0.00730316850743471 GO:0008288 boss receptor activity 4/157 49/18639 0.0816326530612245 9.6914077733004 0.000764352038134658 0.00730316850743471 GO:0036332 placental growth factor receptor activity 4/157 49/18639 0.0816326530612245 9.6914077733004 0.000764352038134658 0.00730316850743471 GO:0038062 protein tyrosine kinase collagen receptor activity 4/157 49/18639 0.0816326530612245 9.6914077733004 0.000764352038134658 0.00730316850743471 GO:0060175 brain-derived neurotrophic factor receptor activity 4/157 49/18639 0.0816326530612245 9.6914077733004 0.000764352038134658 0.00730316850743471 GO:0030021 extracellular matrix structural constituent conferring compression resistance 3/157 22/18639 0.136363636363636 16.1890561667632 0.000802700058138689 0.00730316850743471 GO:0005006 epidermal growth factor receptor activity 4/157 50/18639 0.08 9.4975796178344 0.000825419536466822 0.00730316850743471 GO:0005007 fibroblast growth factor receptor activity 4/157 50/18639 0.08 9.4975796178344 0.000825419536466822 0.00730316850743471 GO:0005017 platelet-derived growth factor receptor activity 4/157 50/18639 0.08 9.4975796178344 0.000825419536466822 0.00730316850743471 GO:0005019 platelet-derived growth factor beta-receptor activity 4/157 50/18639 0.08 9.4975796178344 0.000825419536466822 0.00730316850743471 GO:0005010 insulin-like growth factor receptor activity 4/157 51/18639 0.0784313725490196 9.31135256650431 0.000889850250996678 0.00739120514603363 GO:0005021 vascular endothelial growth factor receptor activity 4/157 51/18639 0.0784313725490196 9.31135256650431 0.000889850250996678 0.00739120514603363 GO:0005030 neurotrophin receptor activity 4/157 51/18639 0.0784313725490196 9.31135256650431 0.000889850250996678 0.00739120514603363 GO:0005158 insulin receptor binding 3/157 23/18639 0.130434782608696 15.4851841595126 0.000917425138494712 0.00746784062734696 GO:0015078 proton transmembrane transporter activity 7/157 185/18639 0.0378378378378378 4.49209846789465 0.000988470196370339 0.00775713545422387 GO:0005003 ephrin receptor activity 4/157 53/18639 0.0754716981132075 8.95998077154188 0.00102920224699776 0.00775713545422387 GO:0005005 transmembrane-ephrin receptor activity 4/157 53/18639 0.0754716981132075 8.95998077154188 0.00102920224699776 0.00775713545422387 GO:0038064 collagen receptor activity 4/157 53/18639 0.0754716981132075 8.95998077154188 0.00102920224699776 0.00775713545422387 GO:0004867 serine-type endopeptidase inhibitor activity 5/157 95/18639 0.0526315789473684 6.2484076433121 0.0012530287571958 0.00927241280324894 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 4/157 58/18639 0.0689655172413793 8.18756863606413 0.00144345213412446 0.0104908039033688 GO:0004714 transmembrane receptor protein tyrosine kinase activity 4/157 60/18639 0.0666666666666667 7.91464968152866 0.00163759705895746 0.0116930175964156 GO:0005126 cytokine receptor binding 8/157 275/18639 0.0290909090909091 3.45366531557614 0.00233810969519856 0.0164070801025141 GO:0016500 protein-hormone receptor activity 4/157 67/18639 0.0597014925373134 7.0877459834585 0.0024596236740388 0.0169672344971829 GO:0035374 chondroitin sulfate binding 2/157 10/18639 0.2 23.743949044586 0.00303488501791012 0.0205866367048237 GO:0042379 chemokine receptor binding 4/157 72/18639 0.0555555555555556 6.59554140127389 0.00319605173630231 0.0213244763389351 GO:0004869 cysteine-type endopeptidase inhibitor activity 3/157 36/18639 0.0833333333333333 9.89331210191083 0.00341428260677134 0.0224131132412248 GO:0048185 activin binding 2/157 11/18639 0.181818181818182 21.5854082223509 0.0036888461600819 0.0234839414779533 GO:0043394 proteoglycan binding 3/157 37/18639 0.0810810810810811 9.62592528834567 0.00369280652233173 0.0234839414779533 GO:0008307 structural constituent of muscle 3/157 42/18639 0.0714285714285714 8.47998180163785 0.00529133070751729 0.0331318707378391 GO:0008191 metalloendopeptidase inhibitor activity 2/157 14/18639 0.142857142857143 16.9599636032757 0.00600306824271887 0.0366306246313255 GO:0030020 extracellular matrix structural constituent conferring tensile strength 3/157 44/18639 0.0681818181818182 8.09452808338159 0.006030102826287 0.0366306246313255 GO:0016651 oxidoreductase activity, acting on NAD(P)H 4/157 88/18639 0.0454545454545455 5.39635205558772 0.00653226617805094 0.0390975343303931 GO:0017171 serine hydrolase activity 6/157 198/18639 0.0303030303030303 3.59756803705848 0.00669554873456257 0.0394876981066054 GO:0004129 cytochrome-c oxidase activity 2/157 15/18639 0.133333333333333 15.8292993630573 0.00688851736012036 0.0394876981066054 GO:0005523 tropomyosin binding 2/157 15/18639 0.133333333333333 15.8292993630573 0.00688851736012036 0.0394876981066054 GO:0016675 oxidoreductase activity, acting on a heme group of donors 2/157 16/18639 0.125 14.8399681528662 0.00782931723524048 0.0442573904825399 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 10/157 484/18639 0.0206611570247934 2.45288729799442 0.00800581400586803 0.0446351547998396 GO:0001216 DNA-binding transcription activator activity 10/157 491/18639 0.0203665987780041 2.41791741798228 0.00880659075466271 0.0484362491506449 GO:0008238 exopeptidase activity 4/157 102/18639 0.0392156862745098 4.65567628325215 0.0108779956497789 0.0590312563928002 GO:0016004 phospholipase activator activity 2/157 20/18639 0.1 11.871974522293 0.012126548173723 0.064669526359465 GO:0016504 peptidase activator activity 3/157 57/18639 0.0526315789473684 6.2484076433121 0.0123061563641358 0.064669526359465 GO:0008013 beta-catenin binding 4/157 106/18639 0.0377358490566038 4.47999038577094 0.0123936684423545 0.064669526359465 GO:0005125 cytokine activity 6/157 234/18639 0.0256410256410256 3.04409603135718 0.0144580217456256 0.0744862639299951 GO:0017134 fibroblast growth factor binding 2/157 23/18639 0.0869565217391304 10.3234561063417 0.0158837083861924 0.0808081724041789 GO:0035401 histone H3Y41 kinase activity 4/157 115/18639 0.0347826086956522 4.12938244253669 0.0162807620077215 0.0808081724041789 GO:0140801 histone H2AXY142 kinase activity 4/157 115/18639 0.0347826086956522 4.12938244253669 0.0162807620077215 0.0808081724041789 GO:0004252 serine-type endopeptidase activity 5/157 176/18639 0.0284090909090909 3.37272003474233 0.0167455594413383 0.0821137673810204 GO:0050431 transforming growth factor beta binding 2/157 24/18639 0.0833333333333333 9.89331210191083 0.017232951241975 0.0825154253586332 GO:0060229 lipase activator activity 2/157 24/18639 0.0833333333333333 9.89331210191083 0.017232951241975 0.0825154253586332 GO:0008235 metalloexopeptidase activity 3/157 66/18639 0.0454545454545455 5.39635205558772 0.0182216695468904 0.086235110530051 GO:0042277 peptide binding 6/157 249/18639 0.0240963855421687 2.86071675235976 0.0190402338819699 0.0890732780455371 GO:1990841 promoter-specific chromatin binding 3/157 68/18639 0.0441176470588235 5.23763581865867 0.0197157800092449 0.0911854825427576 GO:0005160 transforming growth factor beta receptor binding 2/157 26/18639 0.0769230769230769 9.13228809407154 0.0200713799807288 0.091787097215243 GO:0008236 serine-type peptidase activity 5/157 194/18639 0.0257731958762887 3.05978724801366 0.0243263202785051 0.109119842721846 GO:0004181 metallocarboxypeptidase activity 2/157 29/18639 0.0689655172413793 8.18756863606413 0.0246659103941274 0.109119842721846 GO:0043236 laminin binding 2/157 29/18639 0.0689655172413793 8.18756863606413 0.0246659103941274 0.109119842721846 GO:0005179 hormone activity 4/157 132/18639 0.0303030303030303 3.59756803705848 0.0255270933443793 0.111715343990993 GO:0046332 SMAD binding 3/157 79/18639 0.0379746835443038 4.50834475530114 0.0291088028445644 0.126034922954657 GO:0004713 protein tyrosine kinase activity 4/157 140/18639 0.0285714285714286 3.39199272065514 0.0307793464581898 0.131865200089297 GO:0071889 14-3-3 protein binding 2/157 33/18639 0.0606060606060606 7.19513607411697 0.0313856467032641 0.133062064669047 GO:0001540 amyloid-beta binding 3/157 83/18639 0.036144578313253 4.29107512853964 0.0330159151606757 0.138530695571083 GO:0022804 active transmembrane transporter activity 8/157 457/18639 0.0175054704595186 2.07824499296157 0.0399241860511578 0.165516647252596 GO:0005501 retinoid binding 2/157 38/18639 0.0526315789473684 6.2484076433121 0.0406674808974438 0.165516647252596 GO:0019840 isoprenoid binding 2/157 38/18639 0.0526315789473684 6.2484076433121 0.0406674808974438 0.165516647252596 GO:0000217 DNA secondary structure binding 2/157 39/18639 0.0512820512820513 6.08819206271436 0.0426338052150456 0.171801571510134 GO:0035198 miRNA binding 2/157 42/18639 0.0476190476190476 5.6533212010919 0.0487394780290429 0.194480074096279 GO:0001223 transcription coactivator binding 2/157 44/18639 0.0454545454545455 5.39635205558772 0.0529750985960352 0.209328787656178 GO:0042605 peptide antigen binding 2/157 45/18639 0.0444444444444444 5.27643312101911 0.055140386143936 0.215789780390211 GO:0004180 carboxypeptidase activity 2/157 46/18639 0.0434782608695652 5.16172805317087 0.0573364246623589 0.222246903215048 GO:0005504 fatty acid binding 2/157 47/18639 0.0425531914893617 5.05190405203957 0.0595625499990429 0.228697715562363 GO:0019888 protein phosphatase regulator activity 3/157 107/18639 0.0280373831775701 3.32859098755878 0.0617764941340254 0.234981617874283 GO:0048020 CCR chemokine receptor binding 2/157 50/18639 0.04 4.7487898089172 0.0664149379784224 0.250285923677944 GO:0001221 transcription coregulator binding 3/157 115/18639 0.0260869565217391 3.09703683190252 0.0732784998444959 0.267148400001938 GO:0004864 protein phosphatase inhibitor activity 2/157 53/18639 0.0377358490566038 4.47999038577094 0.0735150388211722 0.267148400001938 GO:0016860 intramolecular oxidoreductase activity 2/157 53/18639 0.0377358490566038 4.47999038577094 0.0735150388211722 0.267148400001938 GO:0051018 protein kinase A binding 2/157 53/18639 0.0377358490566038 4.47999038577094 0.0735150388211722 0.267148400001938 GO:0051287 NAD binding 2/157 54/18639 0.037037037037037 4.39702760084926 0.0759339088888809 0.270012293376346 GO:0140463 chromatin-protein adaptor activity 2/157 54/18639 0.037037037037037 4.39702760084926 0.0759339088888809 0.270012293376346 GO:0019208 phosphatase regulator activity 3/157 117/18639 0.0256410256410256 3.04409603135718 0.0762933998483532 0.270012293376346 GO:0140313 molecular sequestering activity 2/157 55/18639 0.0363636363636364 4.31708164447018 0.0783778638624953 0.270650812388976 GO:0019212 phosphatase inhibitor activity 2/157 56/18639 0.0357142857142857 4.23999090081893 0.0808463159573685 0.270650812388976 GO:0003680 minor groove of adenine-thymine-rich DNA binding 1/157 10/18639 0.1 11.871974522293 0.08112874474559 0.270650812388976 GO:0004955 prostaglandin receptor activity 1/157 10/18639 0.1 11.871974522293 0.08112874474559 0.270650812388976 GO:0015279 store-operated calcium channel activity 1/157 10/18639 0.1 11.871974522293 0.08112874474559 0.270650812388976 GO:0031720 haptoglobin binding 1/157 10/18639 0.1 11.871974522293 0.08112874474559 0.270650812388976 GO:0032395 MHC class II receptor activity 1/157 10/18639 0.1 11.871974522293 0.08112874474559 0.270650812388976 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 3/157 122/18639 0.0245901639344262 2.91933799728516 0.0840654607463236 0.271963932209663 GO:0061980 regulatory RNA binding 2/157 58/18639 0.0344827586206897 4.09378431803207 0.0858544003218784 0.271963932209663 GO:0001786 phosphatidylserine binding 2/157 59/18639 0.0338983050847458 4.02439814315017 0.0883928966974498 0.271963932209663 GO:0004954 prostanoid receptor activity 1/157 11/18639 0.0909090909090909 10.7927041111754 0.0888727346041406 0.271963932209663 GO:0005114 type II transforming growth factor beta receptor binding 1/157 11/18639 0.0909090909090909 10.7927041111754 0.0888727346041406 0.271963932209663 GO:0016176 superoxide-generating NADPH oxidase activator activity 1/157 11/18639 0.0909090909090909 10.7927041111754 0.0888727346041406 0.271963932209663 GO:0034713 type I transforming growth factor beta receptor binding 1/157 11/18639 0.0909090909090909 10.7927041111754 0.0888727346041406 0.271963932209663 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding 1/157 11/18639 0.0909090909090909 10.7927041111754 0.0888727346041406 0.271963932209663 GO:0043522 leucine zipper domain binding 1/157 11/18639 0.0909090909090909 10.7927041111754 0.0888727346041406 0.271963932209663 GO:0048407 platelet-derived growth factor binding 1/157 11/18639 0.0909090909090909 10.7927041111754 0.0888727346041406 0.271963932209663 GO:0097493 structural molecule activity conferring elasticity 1/157 11/18639 0.0909090909090909 10.7927041111754 0.0888727346041406 0.271963932209663 GO:0015026 coreceptor activity 2/157 61/18639 0.0327868852459016 3.89245066304688 0.0935360162545668 0.278699376640117 GO:0005078 MAP-kinase scaffold activity 1/157 12/18639 0.0833333333333333 9.89331210191083 0.0965518724969446 0.278699376640117 GO:0008179 adenylate cyclase binding 1/157 12/18639 0.0833333333333333 9.89331210191083 0.0965518724969446 0.278699376640117 GO:0008504 monoamine transmembrane transporter activity 1/157 12/18639 0.0833333333333333 9.89331210191083 0.0965518724969446 0.278699376640117 GO:0035014 phosphatidylinositol 3-kinase regulator activity 1/157 12/18639 0.0833333333333333 9.89331210191083 0.0965518724969446 0.278699376640117 GO:0035497 cAMP response element binding 1/157 12/18639 0.0833333333333333 9.89331210191083 0.0965518724969446 0.278699376640117 GO:0045295 gamma-catenin binding 1/157 12/18639 0.0833333333333333 9.89331210191083 0.0965518724969446 0.278699376640117 GO:0070679 inositol 1,4,5 trisphosphate binding 1/157 12/18639 0.0833333333333333 9.89331210191083 0.0965518724969446 0.278699376640117 GO:0005507 copper ion binding 2/157 63/18639 0.0317460317460317 3.76888080072793 0.0987636849178375 0.283076195503943 GO:0051015 actin filament binding 4/157 209/18639 0.0191387559808612 2.27214823393167 0.100514827561011 0.284246608541052 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 3/157 132/18639 0.0227272727272727 2.69817602779386 0.100568824643517 0.284246608541052 GO:0038024 cargo receptor activity 2/157 65/18639 0.0307692307692308 3.65291523762861 0.104071663094243 0.284535879973091 GO:0043560 insulin receptor substrate binding 1/157 13/18639 0.0769230769230769 9.13228809407154 0.104166698073687 0.284535879973091 GO:0045028 G protein-coupled purinergic nucleotide receptor activity 1/157 13/18639 0.0769230769230769 9.13228809407154 0.104166698073687 0.284535879973091 GO:0045159 myosin II binding 1/157 13/18639 0.0769230769230769 9.13228809407154 0.104166698073687 0.284535879973091 GO:0070123 transforming growth factor beta receptor activity, type III 1/157 13/18639 0.0769230769230769 9.13228809407154 0.104166698073687 0.284535879973091 GO:0001664 G protein-coupled receptor binding 5/157 297/18639 0.0168350168350168 1.99864890947694 0.106577397929896 0.289180006383118 GO:0002020 protease binding 3/157 136/18639 0.0220588235294118 2.61881790932934 0.107507893350274 0.289772931083188 GO:0004065 arylsulfatase activity 1/157 14/18639 0.0714285714285714 8.47998180163785 0.111717746522223 0.291468736118877 GO:0005161 platelet-derived growth factor receptor binding 1/157 14/18639 0.0714285714285714 8.47998180163785 0.111717746522223 0.291468736118877 GO:0005344 oxygen carrier activity 1/157 14/18639 0.0714285714285714 8.47998180163785 0.111717746522223 0.291468736118877 GO:0008494 translation activator activity 1/157 14/18639 0.0714285714285714 8.47998180163785 0.111717746522223 0.291468736118877 GO:1901612 cardiolipin binding 1/157 14/18639 0.0714285714285714 8.47998180163785 0.111717746522223 0.291468736118877 GO:0030295 protein kinase activator activity 3/157 139/18639 0.0215827338129496 2.5622966594877 0.112831790580821 0.292500246919707 GO:0004953 icosanoid receptor activity 1/157 15/18639 0.0666666666666667 7.91464968152866 0.11920554860523 0.301345703616948 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 1/157 15/18639 0.0666666666666667 7.91464968152866 0.11920554860523 0.301345703616948 GO:0051371 muscle alpha-actinin binding 1/157 15/18639 0.0666666666666667 7.91464968152866 0.11920554860523 0.301345703616948 GO:0120283 protein serine/threonine kinase binding 1/157 15/18639 0.0666666666666667 7.91464968152866 0.11920554860523 0.301345703616948 GO:0043539 protein serine/threonine kinase activator activity 2/157 73/18639 0.0273972602739726 3.25259575953233 0.126025911629782 0.306777777937506 GO:0004708 MAP kinase kinase activity 1/157 16/18639 0.0625 7.41998407643312 0.126630630696563 0.306777777937506 GO:0005024 transforming growth factor beta receptor activity 1/157 16/18639 0.0625 7.41998407643312 0.126630630696563 0.306777777937506 GO:0005324 long-chain fatty acid transmembrane transporter activity 1/157 16/18639 0.0625 7.41998407643312 0.126630630696563 0.306777777937506 GO:0015378 sodium:chloride symporter activity 1/157 16/18639 0.0625 7.41998407643312 0.126630630696563 0.306777777937506 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 1/157 16/18639 0.0625 7.41998407643312 0.126630630696563 0.306777777937506 GO:0030275 LRR domain binding 1/157 16/18639 0.0625 7.41998407643312 0.126630630696563 0.306777777937506 GO:0019209 kinase activator activity 3/157 148/18639 0.0202702702702703 2.40648132208642 0.12938359164323 0.307587929309652 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 1/157 17/18639 0.0588235294117647 6.98351442487823 0.133993514817308 0.307587929309652 GO:0008484 sulfuric ester hydrolase activity 1/157 17/18639 0.0588235294117647 6.98351442487823 0.133993514817308 0.307587929309652 GO:0030169 low-density lipoprotein particle binding 1/157 17/18639 0.0588235294117647 6.98351442487823 0.133993514817308 0.307587929309652 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 1/157 17/18639 0.0588235294117647 6.98351442487823 0.133993514817308 0.307587929309652 GO:0045125 bioactive lipid receptor activity 1/157 17/18639 0.0588235294117647 6.98351442487823 0.133993514817308 0.307587929309652 GO:0048038 quinone binding 1/157 17/18639 0.0588235294117647 6.98351442487823 0.133993514817308 0.307587929309652 GO:0070403 NAD+ binding 1/157 17/18639 0.0588235294117647 6.98351442487823 0.133993514817308 0.307587929309652 GO:0017022 myosin binding 2/157 76/18639 0.0263157894736842 3.12420382165605 0.134522485054344 0.307587929309652 GO:0051536 iron-sulfur cluster binding 2/157 76/18639 0.0263157894736842 3.12420382165605 0.134522485054344 0.307587929309652 GO:0051540 metal cluster binding 2/157 77/18639 0.025974025974026 3.08362974605013 0.137382999898637 0.312373636641035 GO:0000400 four-way junction DNA binding 1/157 18/18639 0.0555555555555556 6.59554140127389 0.141294718671549 0.312537774452829 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 1/157 18/18639 0.0555555555555556 6.59554140127389 0.141294718671549 0.312537774452829 GO:0015373 monoatomic anion:sodium symporter activity 1/157 18/18639 0.0555555555555556 6.59554140127389 0.141294718671549 0.312537774452829 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 1/157 18/18639 0.0555555555555556 6.59554140127389 0.141294718671549 0.312537774452829 GO:1901611 phosphatidylglycerol binding 1/157 18/18639 0.0555555555555556 6.59554140127389 0.141294718671549 0.312537774452829 GO:0033293 monocarboxylic acid binding 2/157 79/18639 0.0253164556962025 3.00556317020076 0.143143917300094 0.314916618060207 GO:0008301 DNA binding, bending 1/157 19/18639 0.0526315789473684 6.2484076433121 0.148534755681837 0.323281527072234 GO:0015245 fatty acid transmembrane transporter activity 1/157 19/18639 0.0526315789473684 6.2484076433121 0.148534755681837 0.323281527072234 GO:0001614 purinergic nucleotide receptor activity 1/157 20/18639 0.05 5.9359872611465 0.155714135024369 0.328371258833774 GO:0001972 retinoic acid binding 1/157 20/18639 0.05 5.9359872611465 0.155714135024369 0.328371258833774 GO:0004745 all-trans-retinol dehydrogenase (NAD+) activity 1/157 20/18639 0.05 5.9359872611465 0.155714135024369 0.328371258833774 GO:0005326 neurotransmitter transmembrane transporter activity 1/157 20/18639 0.05 5.9359872611465 0.155714135024369 0.328371258833774 GO:0016502 nucleotide receptor activity 1/157 20/18639 0.05 5.9359872611465 0.155714135024369 0.328371258833774 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 1/157 20/18639 0.05 5.9359872611465 0.155714135024369 0.328371258833774 GO:0010314 phosphatidylinositol-5-phosphate binding 1/157 21/18639 0.0476190476190476 5.6533212010919 0.162833361663887 0.338128460189805 GO:0036122 BMP binding 1/157 21/18639 0.0476190476190476 5.6533212010919 0.162833361663887 0.338128460189805 GO:0072542 protein phosphatase activator activity 1/157 21/18639 0.0476190476190476 5.6533212010919 0.162833361663887 0.338128460189805 GO:0016209 antioxidant activity 2/157 86/18639 0.0232558139534884 2.76092430751 0.163682572515926 0.338166533065897 GO:0005243 gap junction channel activity 1/157 22/18639 0.0454545454545455 5.39635205558772 0.169892936388281 0.347469472914725 GO:0015377 chloride:monoatomic cation symporter activity 1/157 22/18639 0.0454545454545455 5.39635205558772 0.169892936388281 0.347469472914725 GO:0003887 DNA-directed DNA polymerase activity 1/157 23/18639 0.0434782608695652 5.16172805317087 0.176893355842921 0.356413840733014 GO:0004022 alcohol dehydrogenase (NAD+) activity 1/157 23/18639 0.0434782608695652 5.16172805317087 0.176893355842921 0.356413840733014 GO:0031681 G-protein beta-subunit binding 1/157 23/18639 0.0434782608695652 5.16172805317087 0.176893355842921 0.356413840733014 GO:0072341 modified amino acid binding 2/157 91/18639 0.021978021978022 2.60922516973472 0.178655846213529 0.357740435929034 GO:0141003 histone H2AX kinase activity 5/157 354/18639 0.0141242937853107 1.6768325596459 0.17930970252954 0.357740435929034 GO:0043178 alcohol binding 2/157 92/18639 0.0217391304347826 2.58086402658543 0.181675971557055 0.357994692889155 GO:0140996 histone H3 kinase activity 5/157 357/18639 0.0140056022408964 1.66274152973291 0.183572242588372 0.357994692889155 GO:0004806 triacylglycerol lipase activity 1/157 24/18639 0.0416666666666667 4.94665605095541 0.183835112564701 0.357994692889155 GO:0005540 hyaluronic acid binding 1/157 24/18639 0.0416666666666667 4.94665605095541 0.183835112564701 0.357994692889155 GO:0035035 histone acetyltransferase binding 1/157 24/18639 0.0416666666666667 4.94665605095541 0.183835112564701 0.357994692889155 GO:0035173 histone kinase activity 5/157 360/18639 0.0138888888888889 1.64888535031847 0.187872271521253 0.364114354805476 GO:0015296 monoatomic anion:monoatomic cation symporter activity 1/157 25/18639 0.04 4.7487898089172 0.190718695015808 0.366143909770914 GO:0019211 phosphatase activator activity 1/157 25/18639 0.04 4.7487898089172 0.190718695015808 0.366143909770914 GO:0008143 poly(A) binding 1/157 26/18639 0.0384615384615385 4.56614404703577 0.197544587617211 0.373956498419557 GO:0070006 metalloaminopeptidase activity 1/157 26/18639 0.0384615384615385 4.56614404703577 0.197544587617211 0.373956498419557 GO:0070412 R-SMAD binding 1/157 26/18639 0.0384615384615385 4.56614404703577 0.197544587617211 0.373956498419557 GO:0008266 poly(U) RNA binding 1/157 27/18639 0.037037037037037 4.39702760084926 0.204313270781886 0.382471284403286 GO:0023026 MHC class II protein complex binding 1/157 27/18639 0.037037037037037 4.39702760084926 0.204313270781886 0.382471284403286 GO:1901981 phosphatidylinositol phosphate binding 3/157 185/18639 0.0162162162162162 1.92518505766913 0.204861769041563 0.382471284403286 GO:0031406 carboxylic acid binding 3/157 187/18639 0.0160427807486631 1.90459484314861 0.209206240581694 0.385144685765643 GO:0051393 alpha-actinin binding 1/157 28/18639 0.0357142857142857 4.23999090081893 0.21102522094776 0.385144685765643 GO:0051537 2 iron, 2 sulfur cluster binding 1/157 28/18639 0.0357142857142857 4.23999090081893 0.21102522094776 0.385144685765643 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 1/157 28/18639 0.0357142857142857 4.23999090081893 0.21102522094776 0.385144685765643 GO:0097718 disordered domain specific binding 1/157 28/18639 0.0357142857142857 4.23999090081893 0.21102522094776 0.385144685765643 GO:0043177 organic acid binding 3/157 189/18639 0.0158730158730159 1.88444040036397 0.213571370484183 0.388051552620816 GO:0003785 actin monomer binding 1/157 29/18639 0.0344827586206897 4.09378431803207 0.21768091061039 0.392018277072693 GO:0004629 phospholipase C activity 1/157 29/18639 0.0344827586206897 4.09378431803207 0.21768091061039 0.392018277072693 GO:0019207 kinase regulator activity 4/157 287/18639 0.0139372822299652 1.65463059544153 0.223440532562563 0.395161424245183 GO:0001965 G-protein alpha-subunit binding 1/157 30/18639 0.0333333333333333 3.95732484076433 0.224280808355374 0.395161424245183 GO:0008187 poly-pyrimidine tract binding 1/157 30/18639 0.0333333333333333 3.95732484076433 0.224280808355374 0.395161424245183 GO:0035925 mRNA 3'-UTR AU-rich region binding 1/157 30/18639 0.0333333333333333 3.95732484076433 0.224280808355374 0.395161424245183 GO:0051721 protein phosphatase 2A binding 1/157 30/18639 0.0333333333333333 3.95732484076433 0.224280808355374 0.395161424245183 GO:0017147 Wnt-protein binding 1/157 31/18639 0.032258064516129 3.82966920073968 0.230825378890503 0.404939350036356 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/157 32/18639 0.03125 3.70999203821656 0.237315083077637 0.409267961070331 GO:0070717 poly-purine tract binding 1/157 32/18639 0.03125 3.70999203821656 0.237315083077637 0.409267961070331 GO:0071813 lipoprotein particle binding 1/157 32/18639 0.03125 3.70999203821656 0.237315083077637 0.409267961070331 GO:0071814 protein-lipid complex binding 1/157 32/18639 0.03125 3.70999203821656 0.237315083077637 0.409267961070331 GO:1902936 phosphatidylinositol bisphosphate binding 2/157 111/18639 0.018018018018018 2.13909450852126 0.240151575913386 0.412412199986279 GO:0005200 structural constituent of cytoskeleton 2/157 112/18639 0.0178571428571429 2.11999545040946 0.243265978556216 0.41336001596452 GO:0030296 protein tyrosine kinase activator activity 1/157 33/18639 0.0303030303030303 3.59756803705848 0.243750377964336 0.41336001596452 GO:0140311 protein sequestering activity 1/157 33/18639 0.0303030303030303 3.59756803705848 0.243750377964336 0.41336001596452 GO:0003714 transcription corepressor activity 3/157 204/18639 0.0147058823529412 1.74587860621956 0.246877512949656 0.416925924358963 GO:0019825 oxygen binding 1/157 34/18639 0.0294117647058824 3.49175721243912 0.250131716815223 0.41969582905818 GO:0031625 ubiquitin protein ligase binding 4/157 302/18639 0.0132450331125828 1.5724469565951 0.250580065015081 0.41969582905818 GO:0005516 calmodulin binding 3/157 207/18639 0.0144927536231884 1.72057601772362 0.253639241980888 0.423078571664842 GO:0016229 steroid dehydrogenase activity 1/157 35/18639 0.0285714285714286 3.39199272065514 0.256459549143092 0.424305026427799 GO:0034061 DNA polymerase activity 1/157 35/18639 0.0285714285714286 3.39199272065514 0.256459549143092 0.424305026427799 GO:0019213 deacetylase activity 1/157 37/18639 0.027027027027027 3.20864176278189 0.2689564737067 0.436116672504489 GO:0022829 wide pore channel activity 1/157 37/18639 0.027027027027027 3.20864176278189 0.2689564737067 0.436116672504489 GO:0023023 MHC protein complex binding 1/157 37/18639 0.027027027027027 3.20864176278189 0.2689564737067 0.436116672504489 GO:0030280 structural constituent of skin epidermis 1/157 37/18639 0.027027027027027 3.20864176278189 0.2689564737067 0.436116672504489 GO:0042805 actinin binding 1/157 37/18639 0.027027027027027 3.20864176278189 0.2689564737067 0.436116672504489 GO:0004177 aminopeptidase activity 1/157 40/18639 0.025 2.96799363057325 0.287311587123722 0.459293510330826 GO:0071855 neuropeptide receptor binding 1/157 40/18639 0.025 2.96799363057325 0.287311587123722 0.459293510330826 GO:0071949 FAD binding 1/157 40/18639 0.025 2.96799363057325 0.287311587123722 0.459293510330826 GO:0044389 ubiquitin-like protein ligase binding 4/157 322/18639 0.0124223602484472 1.4747794437631 0.287763747258872 0.459293510330826 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 1/157 41/18639 0.024390243902439 2.89560354202268 0.293327613835995 0.464530501288911 GO:0042169 SH2 domain binding 1/157 41/18639 0.024390243902439 2.89560354202268 0.293327613835995 0.464530501288911 GO:0035591 signaling adaptor activity 2/157 129/18639 0.0155038759689922 1.84061620500667 0.296289938253236 0.466882316490088 GO:0042056 chemoattractant activity 1/157 42/18639 0.0238095238095238 2.82666060054595 0.29929317812397 0.466882316490088 GO:0048487 beta-tubulin binding 1/157 42/18639 0.0238095238095238 2.82666060054595 0.29929317812397 0.466882316490088 GO:0016298 lipase activity 2/157 130/18639 0.0153846153846154 1.82645761881431 0.299401190673005 0.466882316490088 GO:0004712 protein serine/threonine/tyrosine kinase activity 1/157 43/18639 0.0232558139534884 2.76092430751 0.305208700575684 0.474121912726349 GO:0045296 cadherin binding 4/157 334/18639 0.0119760479041916 1.42179335596323 0.310453689051601 0.477763628326527 GO:0030547 signaling receptor inhibitor activity 1/157 44/18639 0.0227272727272727 2.69817602779386 0.311074598296142 0.477763628326527 GO:0043014 alpha-tubulin binding 1/157 44/18639 0.0227272727272727 2.69817602779386 0.311074598296142 0.477763628326527 GO:0051539 4 iron, 4 sulfur cluster binding 1/157 45/18639 0.0222222222222222 2.63821656050955 0.316891284935964 0.484867492364427 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 1/157 46/18639 0.0217391304347826 2.58086402658543 0.322659170719822 0.491843754617856 GO:0032266 phosphatidylinositol-3-phosphate binding 1/157 48/18639 0.0208333333333333 2.47332802547771 0.334050163657468 0.507307524658916 GO:0020037 heme binding 2/157 142/18639 0.0140845070422535 1.6721090876469 0.336519108918149 0.509157164794374 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 4/157 349/18639 0.0114613180515759 1.36068475900206 0.339048290047568 0.510137816509385 GO:0001222 transcription corepressor binding 1/157 49/18639 0.0204081632653061 2.4228519433251 0.339674074383399 0.510137816509385 GO:0019903 protein phosphatase binding 2/157 144/18639 0.0138888888888889 1.64888535031847 0.342654835508843 0.510844388469227 GO:0019955 cytokine binding 2/157 144/18639 0.0138888888888889 1.64888535031847 0.342654835508843 0.510844388469227 GO:0033218 amide binding 3/157 247/18639 0.0121457489878543 1.44194022537972 0.345327020612025 0.512949260544139 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 1/157 52/18639 0.0192307692307692 2.28307202351788 0.356264215415092 0.525360636499792 GO:0030159 signaling receptor complex adaptor activity 1/157 52/18639 0.0192307692307692 2.28307202351788 0.356264215415092 0.525360636499792 GO:0017046 peptide hormone binding 1/157 53/18639 0.0188679245283019 2.23999519288547 0.36170169958036 0.529541696867649 GO:0140296 general transcription initiation factor binding 1/157 53/18639 0.0188679245283019 2.23999519288547 0.36170169958036 0.529541696867649 GO:0019887 protein kinase regulator activity 3/157 255/18639 0.0117647058823529 1.39670288497565 0.363713814252972 0.530578933336773 GO:0046906 tetrapyrrole binding 2/157 152/18639 0.0131578947368421 1.56210191082803 0.367009343141114 0.531697767572643 GO:0015485 cholesterol binding 1/157 54/18639 0.0185185185185185 2.19851380042463 0.367093544687746 0.531697767572643 GO:0098632 cell-cell adhesion mediator activity 1/157 55/18639 0.0181818181818182 2.15854082223509 0.372440131369695 0.537528842083213 GO:0170055 lipid transmembrane transporter activity 1/157 56/18639 0.0178571428571429 2.11999545040946 0.377741837104465 0.543228596528506 GO:0140375 immune receptor activity 2/157 156/18639 0.0128205128205128 1.52204801567859 0.379058774973208 0.543228596528506 GO:0004601 peroxidase activity 1/157 57/18639 0.0175438596491228 2.0828025477707 0.382999036242096 0.546949500879064 GO:0140297 DNA-binding transcription factor binding 5/157 488/18639 0.0102459016393443 1.21639083220215 0.393090698303937 0.554000790422897 GO:0004879 nuclear receptor activity 1/157 59/18639 0.0169491525423729 2.01219907157508 0.393381396639355 0.554000790422897 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 1/157 59/18639 0.0169491525423729 2.01219907157508 0.393381396639355 0.554000790422897 GO:0070888 E-box binding 1/157 59/18639 0.0169491525423729 2.01219907157508 0.393381396639355 0.554000790422897 GO:0098531 ligand-modulated transcription factor activity 1/157 60/18639 0.0166666666666667 1.97866242038217 0.398507291188743 0.559284370737304 GO:0005543 phospholipid binding 5/157 497/18639 0.0100603621730382 1.1943636340335 0.408128538188938 0.570818952037449 GO:0030246 carbohydrate binding 3/157 280/18639 0.0107142857142857 1.27199727024568 0.420507408581545 0.586118203057154 GO:0019843 rRNA binding 1/157 65/18639 0.0153846153846154 1.82645761881431 0.423498301745791 0.586271458539241 GO:0160215 deacylase activity 1/157 65/18639 0.0153846153846154 1.82645761881431 0.423498301745791 0.586271458539241 GO:0035091 phosphatidylinositol binding 3/157 284/18639 0.0105633802816901 1.25408181573518 0.429455170706046 0.592502557550375 GO:0003823 antigen binding 2/157 174/18639 0.0114942528735632 1.36459477267736 0.432003366257027 0.593649016066497 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 1/157 67/18639 0.0149253731343284 1.77193649586463 0.433203336048525 0.593649016066497 GO:0032934 sterol binding 1/157 68/18639 0.0147058823529412 1.74587860621956 0.437994800416411 0.598200952246575 GO:0005319 lipid transporter activity 2/157 178/18639 0.0112359550561798 1.33392972160595 0.443448929316416 0.60362446231365 GO:0008028 monocarboxylic acid transmembrane transporter activity 1/157 70/18639 0.0142857142857143 1.69599636032757 0.447457317415732 0.60503364846579 GO:0097110 scaffold protein binding 1/157 70/18639 0.0142857142857143 1.69599636032757 0.447457317415732 0.60503364846579 GO:0016853 isomerase activity 2/157 180/18639 0.0111111111111111 1.31910828025478 0.449124230174015 0.605276694307365 GO:0004521 RNA endonuclease activity 1/157 73/18639 0.0136986301369863 1.62629787976616 0.461355061199969 0.619707953493028 GO:0098631 cell adhesion mediator activity 1/157 76/18639 0.0131578947368421 1.56210191082803 0.474905414891569 0.635810867963384 GO:0019902 phosphatase binding 2/157 190/18639 0.0105263157894737 1.24968152866242 0.477005065578794 0.63652807111662 GO:0015370 solute:sodium symporter activity 1/157 79/18639 0.0126582278481013 1.50278158510038 0.488117007627842 0.649227523217424 GO:0048306 calcium-dependent protein binding 1/157 80/18639 0.0125 1.48399681528662 0.492447052337025 0.652853258309997 GO:0015101 organic cation transmembrane transporter activity 1/157 81/18639 0.0123456790123457 1.46567586694975 0.496740700312836 0.654283058340855 GO:0030971 receptor tyrosine kinase binding 1/157 81/18639 0.0123456790123457 1.46567586694975 0.496740700312836 0.654283058340855 GO:0030165 PDZ domain binding 1/157 83/18639 0.0120481927710843 1.43035837617988 0.505220019511772 0.663304993359003 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 1/157 86/18639 0.0116279069767442 1.380462153755 0.517673541069484 0.675298497484872 GO:0050660 flavin adenine dinucleotide binding 1/157 86/18639 0.0116279069767442 1.380462153755 0.517673541069484 0.675298497484872 GO:0008081 phosphoric diester hydrolase activity 1/157 87/18639 0.0114942528735632 1.36459477267736 0.521755104916414 0.678448331313037 GO:0003727 single-stranded RNA binding 1/157 89/18639 0.0112359550561798 1.33392972160595 0.529815556250196 0.682389023398195 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 1/157 89/18639 0.0112359550561798 1.33392972160595 0.529815556250196 0.682389023398195 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 1/157 89/18639 0.0112359550561798 1.33392972160595 0.529815556250196 0.682389023398195 GO:0140793 histone H2AXY142 phosphatase activity 1/157 90/18639 0.0111111111111111 1.31910828025478 0.533795014884628 0.685345650025374 GO:0052689 carboxylic ester hydrolase activity 1/157 92/18639 0.0108695652173913 1.29043201329272 0.541653808220064 0.693248741967189 GO:0016410 N-acyltransferase activity 1/157 94/18639 0.0106382978723404 1.26297601300989 0.549380955924362 0.698743903316298 GO:0042562 hormone binding 1/157 94/18639 0.0106382978723404 1.26297601300989 0.549380955924362 0.698743903316298 GO:0004896 cytokine receptor activity 1/157 96/18639 0.0104166666666667 1.23666401273885 0.556978649342841 0.706200343559303 GO:0004725 protein tyrosine phosphatase activity 1/157 98/18639 0.0102040816326531 1.21142597166255 0.564449043575585 0.713449567500817 GO:0000287 magnesium ion binding 2/157 230/18639 0.00869565217391304 1.03234561063417 0.57949076650151 0.73019424757311 GO:0005496 steroid binding 1/157 108/18639 0.00925925925925926 1.09925690021231 0.599964492533392 0.751763213230862 GO:0003712 transcription coregulator activity 4/157 495/18639 0.00808080808080808 0.959351476548929 0.602779232866845 0.751763213230862 GO:0004620 phospholipase activity 1/157 109/18639 0.00917431192660551 1.08917197452229 0.603353709233638 0.751763213230862 GO:0046982 protein heterodimerization activity 3/157 369/18639 0.00813008130081301 0.965201180674227 0.603996488271479 0.751763213230862 GO:0005525 GTP binding 3/157 378/18639 0.00793650793650794 0.942220200181983 0.620331560905339 0.769740686855101 GO:0017124 SH3 domain binding 1/157 115/18639 0.00869565217391304 1.03234561063417 0.623098099885829 0.770823485269096 GO:0015294 solute:monoatomic cation symporter activity 1/157 116/18639 0.00862068965517241 1.02344607950802 0.626292528644085 0.772427451994371 GO:1990782 protein tyrosine kinase binding 1/157 117/18639 0.00854700854700855 1.01469867711906 0.629460054045093 0.773988646514661 GO:0004540 RNA nuclease activity 1/157 121/18639 0.00826446280991736 0.981154919197768 0.641865596864754 0.784502396168033 GO:0015108 chloride transmembrane transporter activity 1/157 121/18639 0.00826446280991736 0.981154919197768 0.641865596864754 0.784502396168033 GO:0008528 G protein-coupled peptide receptor activity 1/157 122/18639 0.00819672131147541 0.973112665761721 0.644901945352292 0.785853568138871 GO:0003730 mRNA 3'-UTR binding 2/157 262/18639 0.00763358778625954 0.906257597121602 0.650409916932822 0.790199511019877 GO:0019001 guanyl nucleotide binding 3/157 400/18639 0.0075 0.890398089171974 0.65832213315342 0.790852834091799 GO:0032561 guanyl ribonucleotide binding 3/157 400/18639 0.0075 0.890398089171974 0.65832213315342 0.790852834091799 GO:0004519 endonuclease activity 1/157 127/18639 0.0078740157480315 0.934801143487637 0.659704239427308 0.790852834091799 GO:0001653 peptide receptor activity 1/157 128/18639 0.0078125 0.92749800955414 0.662590282772701 0.790852834091799 GO:0031490 chromatin DNA binding 1/157 128/18639 0.0078125 0.92749800955414 0.662590282772701 0.790852834091799 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 2/157 268/18639 0.00746268656716418 0.885968247932313 0.662606428563399 0.790852834091799 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 1/157 130/18639 0.00769230769230769 0.913228809407153 0.668289607420005 0.795303714093398 GO:0005262 calcium channel activity 1/157 131/18639 0.00763358778625954 0.906257597121602 0.671103294363387 0.796323734127984 GO:0001217 DNA-binding transcription repressor activity 2/157 278/18639 0.00719424460431655 0.854098886495899 0.682176715174617 0.805554088155379 GO:0016779 nucleotidyltransferase activity 1/157 136/18639 0.00735294117647059 0.872939303109779 0.684819937350764 0.805554088155379 GO:0140789 histone phosphatase activity 1/157 136/18639 0.00735294117647059 0.872939303109779 0.684819937350764 0.805554088155379 GO:0016922 nuclear receptor binding 1/157 137/18639 0.0072992700729927 0.866567483379051 0.687494275016869 0.806369365797883 GO:0031267 small GTPase binding 2/157 283/18639 0.00706713780918728 0.839008800162049 0.691611575407986 0.807907236890899 GO:0070851 growth factor receptor binding 1/157 139/18639 0.00719424460431655 0.854098886495899 0.692775493058781 0.807907236890899 GO:0015293 symporter activity 1/157 146/18639 0.00684931506849315 0.813148939883082 0.710570963394108 0.82629252028972 GO:0015085 calcium ion transmembrane transporter activity 1/157 147/18639 0.00680272108843537 0.8076173144417 0.7130281287403 0.826787602271516 GO:0008509 monoatomic anion transmembrane transporter activity 1/157 149/18639 0.00671140939597315 0.796776813576711 0.717880446657573 0.830049266447819 GO:0005506 iron ion binding 1/157 154/18639 0.00649350649350649 0.770907436512532 0.729657508362399 0.841276503975911 GO:0051020 GTPase binding 2/157 315/18639 0.00634920634920635 0.753776160145587 0.746668438297089 0.858457780753997 GO:0015081 sodium ion transmembrane transporter activity 1/157 164/18639 0.00609756097560976 0.72390088550567 0.751765885808469 0.861874371830972 GO:0015103 inorganic anion transmembrane transporter activity 1/157 165/18639 0.00606060606060606 0.719513607411697 0.753875371920949 0.861874371830972 GO:0003735 structural constituent of ribosome 1/157 175/18639 0.00571428571428571 0.678398544131028 0.774014765661216 0.879955334145572 GO:0004721 phosphoprotein phosphatase activity 1/157 175/18639 0.00571428571428571 0.678398544131028 0.774014765661216 0.879955334145572 GO:0046943 carboxylic acid transmembrane transporter activity 1/157 188/18639 0.00531914893617021 0.631488006504947 0.797766828124021 0.903865187366575 GO:0005342 organic acid transmembrane transporter activity 1/157 189/18639 0.00529100529100529 0.628146800121322 0.799487635017118 0.903865187366575 GO:0042578 phosphoric ester hydrolase activity 2/157 363/18639 0.00550964187327824 0.654103279465179 0.813432202879517 0.91708284368965 GO:0016829 lyase activity 1/157 200/18639 0.005 0.59359872611465 0.817482611335513 0.919103377937994 GO:0004518 nuclease activity 1/157 209/18639 0.00478468899521531 0.568037058482918 0.831004933905611 0.920744252323114 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 1/157 229/18639 0.00436681222707424 0.518426835034628 0.857594779745283 0.920744252323114 GO:0005085 guanyl-nucleotide exchange factor activity 1/157 230/18639 0.00434782608695652 0.516172805317087 0.858809207750714 0.920744252323114 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 1/157 243/18639 0.00411522633744856 0.488558622316584 0.873691100740525 0.920744252323114 GO:0004676 3-phosphoinositide-dependent protein kinase activity 1/157 245/18639 0.00408163265306122 0.48457038866502 0.875837916381956 0.920744252323114 GO:0004711 ribosomal protein S6 kinase activity 1/157 245/18639 0.00408163265306122 0.48457038866502 0.875837916381956 0.920744252323114 GO:0035175 histone H3S10 kinase activity 1/157 245/18639 0.00408163265306122 0.48457038866502 0.875837916381956 0.920744252323114 GO:0035979 histone H2AXS139 kinase activity 1/157 245/18639 0.00408163265306122 0.48457038866502 0.875837916381956 0.920744252323114 GO:0044022 histone H3S28 kinase activity 1/157 245/18639 0.00408163265306122 0.48457038866502 0.875837916381956 0.920744252323114 GO:0044023 histone H4S1 kinase activity 1/157 245/18639 0.00408163265306122 0.48457038866502 0.875837916381956 0.920744252323114 GO:0044024 histone H2AS1 kinase activity 1/157 245/18639 0.00408163265306122 0.48457038866502 0.875837916381956 0.920744252323114 GO:0044025 histone H2BS14 kinase activity 1/157 245/18639 0.00408163265306122 0.48457038866502 0.875837916381956 0.920744252323114 GO:0072354 histone H3T3 kinase activity 1/157 245/18639 0.00408163265306122 0.48457038866502 0.875837916381956 0.920744252323114 GO:0072371 histone H2AS121 kinase activity 1/157 245/18639 0.00408163265306122 0.48457038866502 0.875837916381956 0.920744252323114 GO:0072518 Rho-dependent protein serine/threonine kinase activity 1/157 245/18639 0.00408163265306122 0.48457038866502 0.875837916381956 0.920744252323114 GO:0140823 histone H2BS36 kinase activity 1/157 245/18639 0.00408163265306122 0.48457038866502 0.875837916381956 0.920744252323114 GO:0140855 histone H3S57 kinase activity 1/157 245/18639 0.00408163265306122 0.48457038866502 0.875837916381956 0.920744252323114 GO:0140995 histone H2A kinase activity 1/157 245/18639 0.00408163265306122 0.48457038866502 0.875837916381956 0.920744252323114 GO:0140997 histone H4 kinase activity 1/157 245/18639 0.00408163265306122 0.48457038866502 0.875837916381956 0.920744252323114 GO:0140998 histone H2B kinase activity 1/157 245/18639 0.00408163265306122 0.48457038866502 0.875837916381956 0.920744252323114 GO:1990244 histone H2AT120 kinase activity 1/157 245/18639 0.00408163265306122 0.48457038866502 0.875837916381956 0.920744252323114 GO:0004677 DNA-dependent protein kinase activity 1/157 246/18639 0.0040650406504065 0.482600590337114 0.876897688434149 0.920744252323114 GO:0140857 histone H3T45 kinase activity 1/157 246/18639 0.0040650406504065 0.482600590337114 0.876897688434149 0.920744252323114 GO:0035402 histone H3T11 kinase activity 1/157 247/18639 0.00404858299595142 0.480646741793239 0.877948472042904 0.920744252323114 GO:0035403 histone H3T6 kinase activity 1/157 247/18639 0.00404858299595142 0.480646741793239 0.877948472042904 0.920744252323114 GO:0004679 AMP-activated protein kinase activity 1/157 248/18639 0.00403225806451613 0.478708650092459 0.878990342959024 0.920744252323114 GO:0140104 molecular carrier activity 1/157 249/18639 0.00401606425702811 0.476786125393293 0.880023376298996 0.920744252323114 GO:0004674 protein serine/threonine kinase activity 2/157 433/18639 0.0046189376443418 0.548359100336859 0.88286522217789 0.921349090836926 GO:0003713 transcription coactivator activity 1/157 256/18639 0.00390625 0.46374900477707 0.887013336544473 0.923310557477239 GO:0046873 metal ion transmembrane transporter activity 2/157 450/18639 0.00444444444444444 0.527643312101911 0.89569417534317 0.929762728659665 GO:0008514 organic anion transmembrane transporter activity 1/157 269/18639 0.00371747211895911 0.441337342836171 0.898938433230124 0.929762728659665 GO:0005096 GTPase activator activity 1/157 271/18639 0.003690036900369 0.438080240675018 0.900658552076616 0.929762728659665 GO:0016791 phosphatase activity 1/157 273/18639 0.00366300366300366 0.434870861622454 0.902349576954712 0.929762728659665 GO:0015291 secondary active transmembrane transporter activity 1/157 287/18639 0.00348432055749129 0.413657648860383 0.913412183218306 0.938784743863259 GO:0030695 GTPase regulator activity 2/157 489/18639 0.00408997955010225 0.485561330155133 0.920369530964659 0.941748916301489 GO:0060589 nucleoside-triphosphatase regulator activity 2/157 490/18639 0.00408163265306122 0.48457038866502 0.920924001690399 0.941748916301489 GO:0003924 GTPase activity 1/157 331/18639 0.00302114803625378 0.358669925144803 0.940695953931586 0.959557025689613 GO:0140097 catalytic activity, acting on DNA 1/157 336/18639 0.00297619047619048 0.353332575068244 0.943195788280392 0.959701714575299 GO:0005261 monoatomic cation channel activity 1/157 341/18639 0.00293255131964809 0.348151745521789 0.945590890459978 0.959739382586561 GO:0045182 translation regulator activity 1/157 356/18639 0.00280898876404494 0.333482430401489 0.952190517819721 0.963679584686733 GO:0106310 protein serine kinase activity 1/157 361/18639 0.00277008310249307 0.328863560174321 0.954208532257379 0.963679584686733 GO:0015631 tubulin binding 1/157 385/18639 0.0025974025974026 0.308362974605013 0.962776998087628 0.968172163942135 GO:0140098 catalytic activity, acting on RNA 1/157 387/18639 0.00258397932816537 0.306769367501111 0.96341456117092 0.968172163942135 GO:0005216 monoatomic ion channel activity 1/157 448/18639 0.00223214285714286 0.264999431301183 0.978419306711979 0.980829206482205 GO:0016755 aminoacyltransferase activity 1/157 496/18639 0.00201612903225806 0.23935432504623 0.985772318783414 0.985772318783414