ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0005201 extracellular matrix structural constituent 31/366 168/18639 0.18452380952381 9.3971018735363 1.84483682026484e-21 1.12350562354129e-18 GO:0019838 growth factor binding 21/366 136/18639 0.154411764705882 7.86360896817744 2.52414432778381e-13 7.68601947810169e-11 GO:0005178 integrin binding 21/366 161/18639 0.130434782608696 6.64255167498218 7.27857869676873e-12 1.47755147544405e-09 GO:0005518 collagen binding 14/366 72/18639 0.194444444444444 9.90232240437158 1.05479117094458e-10 1.60591955776312e-08 GO:0050840 extracellular matrix binding 13/366 67/18639 0.194029850746269 9.88120871054563 5.0865330577291e-10 6.19539726431405e-08 GO:0005520 insulin-like growth factor binding 8/366 19/18639 0.421052631578947 21.4426229508197 1.28190048457335e-09 1.30112899184195e-07 GO:0031994 insulin-like growth factor I binding 7/366 13/18639 0.538461538461538 27.421815889029 1.64841870496924e-09 1.43412427332324e-07 GO:0005539 glycosaminoglycan binding 21/366 242/18639 0.0867768595041322 4.41921826310798 1.42666660291432e-08 1.08604995146852e-06 GO:0043394 proteoglycan binding 9/366 37/18639 0.243243243243243 12.3874612317235 3.01286495540015e-08 2.03870528648744e-06 GO:0033218 amide binding 20/366 247/18639 0.0809716599190283 4.12358133669609 9.98443718402904e-08 6.08052224507369e-06 GO:0061134 peptidase regulator activity 19/366 226/18639 0.084070796460177 4.28140867546787 1.16112875689956e-07 6.42843102683483e-06 GO:0003779 actin binding 27/366 443/18639 0.0609480812641084 3.10385597454021 2.19298184852693e-07 1.11293828812742e-05 GO:0002020 protease binding 14/366 136/18639 0.102941176470588 5.24240597878496 4.82215592487462e-07 2.25899458326819e-05 GO:0001540 amyloid-beta binding 11/366 83/18639 0.132530120481928 6.74925933241161 6.56957042022136e-07 2.85776313279629e-05 GO:0048407 platelet-derived growth factor binding 5/366 11/18639 0.454545454545455 23.1482861400894 1.19093019681008e-06 4.83517659904894e-05 GO:0008201 heparin binding 15/366 172/18639 0.0872093023255814 4.44124094548227 1.59516318892787e-06 5.80412579821189e-05 GO:0001216 DNA-binding transcription activator activity 27/366 491/18639 0.054989816700611 2.80042402590898 1.6201993196979e-06 5.80412579821189e-05 GO:0004866 endopeptidase inhibitor activity 14/366 161/18639 0.0869565217391304 4.42836778332145 3.67486728729546e-06 0.000118085807246878 GO:0061135 endopeptidase regulator activity 15/366 184/18639 0.0815217391304348 4.15159479686386 3.69869877915681e-06 0.000118085807246878 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 26/366 484/18639 0.0537190082644628 2.73570654382875 3.87802322649846e-06 0.000118085807246878 GO:0030414 peptidase inhibitor activity 14/366 169/18639 0.0828402366863905 4.21874090600446 6.47111311356534e-06 0.000187662280293395 GO:0004857 enzyme inhibitor activity 23/366 416/18639 0.0552884615384615 2.8156328814628 8.8919823801254e-06 0.000234996867590262 GO:1901681 sulfur compound binding 18/366 275/18639 0.0654545454545455 3.33335320417288 9.05993552200925e-06 0.000234996867590262 GO:0042277 peptide binding 17/366 249/18639 0.0682730923694779 3.47689117124235 9.26096029912361e-06 0.000234996867590262 GO:0030020 extracellular matrix structural constituent conferring tensile strength 7/366 44/18639 0.159090909090909 8.1019001490313 2.17874534754506e-05 0.000513632467638775 GO:0001968 fibronectin binding 6/366 30/18639 0.2 10.1852459016393 2.19284797349888e-05 0.000513632467638775 GO:0070325 lipoprotein particle receptor binding 6/366 31/18639 0.193548387096774 9.85668958223162 2.67444483367801e-05 0.000603235890262929 GO:0019864 IgG binding 4/366 11/18639 0.363636363636364 18.5186289120715 4.32731633081508e-05 0.00094119130195228 GO:0140375 immune receptor activity 12/366 156/18639 0.0769230769230769 3.91740226986129 6.11755996708706e-05 0.00128468759308828 GO:0051015 actin filament binding 14/366 209/18639 0.0669856459330144 3.41132637853949 6.9678188482647e-05 0.00140305346432768 GO:0004602 glutathione peroxidase activity 5/366 23/18639 0.217391304347826 11.0709194583036 7.14197986767785e-05 0.00140305346432768 GO:0050431 transforming growth factor beta binding 5/366 24/18639 0.208333333333333 10.609631147541 8.87694912889908e-05 0.00168939438109361 GO:0008191 metalloendopeptidase inhibitor activity 4/366 14/18639 0.285714285714286 14.5503512880562 0.000125266348953209 0.00225023164689896 GO:0019865 immunoglobulin binding 5/366 26/18639 0.192307692307692 9.79350567465322 0.000133018619521121 0.00225023164689896 GO:0043548 phosphatidylinositol 3-kinase binding 5/366 26/18639 0.192307692307692 9.79350567465322 0.000133018619521121 0.00225023164689896 GO:0050750 low-density lipoprotein particle receptor binding 5/366 26/18639 0.192307692307692 9.79350567465322 0.000133018619521121 0.00225023164689896 GO:0019199 transmembrane receptor protein kinase activity 8/366 78/18639 0.102564102564103 5.22320302648171 0.000145004122251304 0.00238668947164984 GO:0008009 chemokine activity 6/366 45/18639 0.133333333333333 6.79016393442623 0.000234742931833419 0.00376206435490927 GO:0008013 beta-catenin binding 9/366 106/18639 0.0849056603773585 4.32392514692236 0.000242104217372632 0.00378055047128033 GO:0005004 GPI-linked ephrin receptor activity 6/366 49/18639 0.122448979591837 6.23586483773837 0.000377314348863225 0.00468947833587151 GO:0005008 hepatocyte growth factor receptor activity 6/366 49/18639 0.122448979591837 6.23586483773837 0.000377314348863225 0.00468947833587151 GO:0005009 insulin receptor activity 6/366 49/18639 0.122448979591837 6.23586483773837 0.000377314348863225 0.00468947833587151 GO:0005011 macrophage colony-stimulating factor receptor activity 6/366 49/18639 0.122448979591837 6.23586483773837 0.000377314348863225 0.00468947833587151 GO:0005018 platelet-derived growth factor alpha-receptor activity 6/366 49/18639 0.122448979591837 6.23586483773837 0.000377314348863225 0.00468947833587151 GO:0005020 stem cell factor receptor activity 6/366 49/18639 0.122448979591837 6.23586483773837 0.000377314348863225 0.00468947833587151 GO:0008288 boss receptor activity 6/366 49/18639 0.122448979591837 6.23586483773837 0.000377314348863225 0.00468947833587151 GO:0036332 placental growth factor receptor activity 6/366 49/18639 0.122448979591837 6.23586483773837 0.000377314348863225 0.00468947833587151 GO:0038062 protein tyrosine kinase collagen receptor activity 6/366 49/18639 0.122448979591837 6.23586483773837 0.000377314348863225 0.00468947833587151 GO:0060175 brain-derived neurotrophic factor receptor activity 6/366 49/18639 0.122448979591837 6.23586483773837 0.000377314348863225 0.00468947833587151 GO:0005006 epidermal growth factor receptor activity 6/366 50/18639 0.12 6.11114754098361 0.000421766410368062 0.00484633479083301 GO:0005007 fibroblast growth factor receptor activity 6/366 50/18639 0.12 6.11114754098361 0.000421766410368062 0.00484633479083301 GO:0005017 platelet-derived growth factor receptor activity 6/366 50/18639 0.12 6.11114754098361 0.000421766410368062 0.00484633479083301 GO:0005019 platelet-derived growth factor beta-receptor activity 6/366 50/18639 0.12 6.11114754098361 0.000421766410368062 0.00484633479083301 GO:0005010 insulin-like growth factor receptor activity 6/366 51/18639 0.117647058823529 5.99132111861138 0.000470201065819714 0.00511343659078939 GO:0005021 vascular endothelial growth factor receptor activity 6/366 51/18639 0.117647058823529 5.99132111861138 0.000470201065819714 0.00511343659078939 GO:0005030 neurotrophin receptor activity 6/366 51/18639 0.117647058823529 5.99132111861138 0.000470201065819714 0.00511343659078939 GO:0004867 serine-type endopeptidase inhibitor activity 8/366 95/18639 0.0842105263157895 4.28852459016393 0.000563412041309896 0.00569703046317187 GO:0019955 cytokine binding 10/366 144/18639 0.0694444444444444 3.53654371584699 0.000563600683467987 0.00569703046317187 GO:0005003 ephrin receptor activity 6/366 53/18639 0.113207547169811 5.76523352922982 0.00057999324912423 0.00569703046317187 GO:0005005 transmembrane-ephrin receptor activity 6/366 53/18639 0.113207547169811 5.76523352922982 0.00057999324912423 0.00569703046317187 GO:0017046 peptide hormone binding 6/366 53/18639 0.113207547169811 5.76523352922982 0.00057999324912423 0.00569703046317187 GO:0038064 collagen receptor activity 6/366 53/18639 0.113207547169811 5.76523352922982 0.00057999324912423 0.00569703046317187 GO:0140313 molecular sequestering activity 6/366 55/18639 0.109090909090909 5.55558867362146 0.000708709840225073 0.00685086178884238 GO:0030021 extracellular matrix structural constituent conferring compression resistance 4/366 22/18639 0.181818181818182 9.25931445603577 0.000808467081370748 0.00761994639415938 GO:0005522 profilin binding 3/366 10/18639 0.3 15.277868852459 0.000813294771133595 0.00761994639415938 GO:0097493 structural molecule activity conferring elasticity 3/366 11/18639 0.272727272727273 13.8889716840537 0.00110205287406814 0.0101689424289014 GO:0004714 transmembrane receptor protein tyrosine kinase activity 6/366 60/18639 0.1 5.09262295081967 0.00112748887387203 0.0101696553720866 GO:0005126 cytokine receptor binding 14/366 275/18639 0.0509090909090909 2.59260804769001 0.00113552802184219 0.0101696553720866 GO:0004222 metalloendopeptidase activity 8/366 110/18639 0.0727272727272727 3.70372578241431 0.0014738960898445 0.013008735053845 GO:0023026 MHC class II protein complex binding 4/366 27/18639 0.148148148148148 7.54462659380692 0.00179535397080282 0.0156195795459845 GO:0016500 protein-hormone receptor activity 6/366 67/18639 0.0895522388059701 4.56055786640568 0.00200411233106245 0.0171902029523526 GO:0032934 sterol binding 6/366 68/18639 0.0882352941176471 4.49349083895853 0.00216241603702954 0.0182904356465415 GO:0043178 alcohol binding 7/366 92/18639 0.0760869565217391 3.87482181040627 0.00223018713035 0.0186052597586733 GO:0005161 platelet-derived growth factor receptor binding 3/366 14/18639 0.214285714285714 10.9127634660422 0.00232708730842211 0.0186872557568467 GO:0019763 immunoglobulin receptor activity 3/366 14/18639 0.214285714285714 10.9127634660422 0.00232708730842211 0.0186872557568467 GO:0051861 glycolipid binding 4/366 29/18639 0.137931034482759 7.02430751837196 0.00235589916849749 0.0186872557568467 GO:0005125 cytokine activity 12/366 234/18639 0.0512820512820513 2.61160151324086 0.00236275647500361 0.0186872557568467 GO:0042562 hormone binding 7/366 94/18639 0.074468085106383 3.79237879316359 0.00252059207116605 0.0196800073248734 GO:0004175 endopeptidase activity 17/366 405/18639 0.0419753086419753 2.13764420157863 0.00283924161779722 0.0218873182941583 GO:0042379 chemokine receptor binding 6/366 72/18639 0.0833333333333333 4.24385245901639 0.00289152781216118 0.022011755470077 GO:0071813 lipoprotein particle binding 4/366 32/18639 0.125 6.36577868852459 0.00340589912518439 0.0252950313077719 GO:0071814 protein-lipid complex binding 4/366 32/18639 0.125 6.36577868852459 0.00340589912518439 0.0252950313077719 GO:0008237 metallopeptidase activity 10/366 184/18639 0.0543478260869565 2.76772986457591 0.00353272211589781 0.0259208164889369 GO:0071889 14-3-3 protein binding 4/366 33/18639 0.121212121212121 6.17287630402385 0.00381653664517059 0.0273443625518693 GO:0140311 protein sequestering activity 4/366 33/18639 0.121212121212121 6.17287630402385 0.00381653664517059 0.0273443625518693 GO:0015485 cholesterol binding 5/366 54/18639 0.0925925925925926 4.71539162112933 0.00408364564955518 0.0289179093090594 GO:0030169 low-density lipoprotein particle binding 3/366 17/18639 0.176470588235294 8.98698167791707 0.00416169068380558 0.029131834786639 GO:0033293 monocarboxylic acid binding 6/366 79/18639 0.0759493670886076 3.86781489935671 0.00458968956022191 0.0307719553030682 GO:0046332 SMAD binding 6/366 79/18639 0.0759493670886076 3.86781489935671 0.00458968956022191 0.0307719553030682 GO:0005543 phospholipid binding 19/366 497/18639 0.0382293762575453 1.94687798924696 0.00459052720124911 0.0307719553030682 GO:0019207 kinase regulator activity 13/366 287/18639 0.0452961672473868 2.30676300908208 0.00459810826367685 0.0307719553030682 GO:0008083 growth factor activity 9/366 162/18639 0.0555555555555556 2.8292349726776 0.00479629384312799 0.0317493798963581 GO:0004601 peroxidase activity 5/366 57/18639 0.087719298245614 4.4672131147541 0.0051549132365051 0.0332529668362156 GO:0016504 peptidase activator activity 5/366 57/18639 0.087719298245614 4.4672131147541 0.0051549132365051 0.0332529668362156 GO:0001618 virus receptor activity 6/366 81/18639 0.0740740740740741 3.77231329690346 0.00518724441615843 0.0332529668362156 GO:0140272 exogenous protein binding 6/366 82/18639 0.0731707317073171 3.72630947620952 0.00550651790694785 0.0349319729722004 GO:0043395 heparan sulfate proteoglycan binding 3/366 19/18639 0.157894736842105 8.04098360655738 0.00576080134474173 0.0356360506096521 GO:0097001 ceramide binding 3/366 19/18639 0.157894736842105 8.04098360655738 0.00576080134474173 0.0356360506096521 GO:0023023 MHC protein complex binding 4/366 37/18639 0.108108108108108 5.50553832521046 0.00579305256216019 0.0356360506096521 GO:0001786 phosphatidylserine binding 5/366 59/18639 0.0847457627118644 4.31578216171159 0.0059709598607605 0.0360031144079519 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 5/366 59/18639 0.0847457627118644 4.31578216171159 0.0059709598607605 0.0360031144079519 GO:0016004 phospholipase activator activity 3/366 20/18639 0.15 7.63893442622951 0.00667994229718995 0.0398831848920459 GO:0016209 antioxidant activity 6/366 86/18639 0.0697674418604651 3.55299275638582 0.00692850109879101 0.0409656035841138 GO:0001530 lipopolysaccharide binding 4/366 41/18639 0.0975609756097561 4.96841263494602 0.00835521907524122 0.0489262347771337 GO:0008093 cytoskeletal anchor activity 3/366 22/18639 0.136363636363636 6.94448584202683 0.00876648318223411 0.0508456024569578 GO:0038024 cargo receptor activity 5/366 65/18639 0.0769230769230769 3.91740226986129 0.00895818368239555 0.0512839444493517 GO:0072341 modified amino acid binding 6/366 91/18639 0.0659340659340659 3.35777337416682 0.00905825612644084 0.0512839444493517 GO:0042056 chemoattractant activity 4/366 42/18639 0.0952380952380952 4.85011709601874 0.00909468965604266 0.0512839444493517 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 14/366 349/18639 0.0401146131805158 2.04288599746348 0.00943442904890848 0.0527116265209657 GO:0030547 signaling receptor inhibitor activity 4/366 44/18639 0.0909090909090909 4.62965722801788 0.010698616038956 0.0592314287974925 GO:0060229 lipase activator activity 3/366 24/18639 0.125 6.36577868852459 0.0111938107631357 0.0614146914842311 GO:0004896 cytokine receptor activity 6/366 96/18639 0.0625 3.18288934426229 0.0116194575861861 0.0631808006248872 GO:0031406 carboxylic acid binding 9/366 187/18639 0.0481283422459893 2.45099500306829 0.01180042746872 0.0635969940570837 GO:0120020 cholesterol transfer activity 3/366 25/18639 0.12 6.11114754098361 0.0125382365231611 0.066634303861957 GO:0043177 organic acid binding 9/366 189/18639 0.0476190476190476 2.42505854800937 0.0125828324205666 0.066634303861957 GO:0005504 fatty acid binding 4/366 47/18639 0.0851063829787234 4.33414719218695 0.0134290550619815 0.0705025390754028 GO:0046982 protein heterodimerization activity 14/366 369/18639 0.037940379403794 1.93216046914567 0.0147617078447466 0.076836581858553 GO:0004364 glutathione transferase activity 3/366 27/18639 0.111111111111111 5.65846994535519 0.0154930353705051 0.0791269739863203 GO:0032395 MHC class II receptor activity 2/366 10/18639 0.2 10.1852459016393 0.0155915219677478 0.0791269739863203 GO:0043208 glycosphingolipid binding 2/366 10/18639 0.2 10.1852459016393 0.0155915219677478 0.0791269739863203 GO:0048020 CCR chemokine receptor binding 4/366 50/18639 0.08 4.07409836065574 0.016566287548651 0.0832669092468544 GO:0140297 DNA-binding transcription factor binding 17/366 488/18639 0.0348360655737705 1.77406947057243 0.0166807273039675 0.0832669092468544 GO:0046625 sphingolipid binding 3/366 28/18639 0.107142857142857 5.45638173302108 0.0171046987351934 0.0846891181279089 GO:0043236 laminin binding 3/366 29/18639 0.103448275862069 5.26823063877897 0.0188064833005814 0.0888073258064838 GO:0003953 NAD+ nucleosidase activity 2/366 11/18639 0.181818181818182 9.25931445603577 0.0188114039885655 0.0888073258064838 GO:0008199 ferric iron binding 2/366 11/18639 0.181818181818182 9.25931445603577 0.0188114039885655 0.0888073258064838 GO:0016176 superoxide-generating NADPH oxidase activator activity 2/366 11/18639 0.181818181818182 9.25931445603577 0.0188114039885655 0.0888073258064838 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 2/366 11/18639 0.181818181818182 9.25931445603577 0.0188114039885655 0.0888073258064838 GO:0050998 nitric-oxide synthase binding 2/366 11/18639 0.181818181818182 9.25931445603577 0.0188114039885655 0.0888073258064838 GO:0019888 protein phosphatase regulator activity 6/366 107/18639 0.0560747663551402 2.85567642102038 0.0189719774288174 0.0888764173396137 GO:0005496 steroid binding 6/366 108/18639 0.0555555555555556 2.8292349726776 0.0197677098231776 0.0918972158955354 GO:0070851 growth factor receptor binding 7/366 139/18639 0.0503597122302158 2.56463026300271 0.0200099292409351 0.0923185371797688 GO:0001965 G-protein alpha-subunit binding 3/366 30/18639 0.1 5.09262295081967 0.0205986727367157 0.0943202383207509 GO:0005516 calmodulin binding 9/366 207/18639 0.0434782608695652 2.21418389166073 0.0214579609381663 0.0975216284428602 GO:0035014 phosphatidylinositol 3-kinase regulator activity 2/366 12/18639 0.166666666666667 8.48770491803279 0.0222840643788938 0.0997867294613702 GO:0035259 nuclear glucocorticoid receptor binding 2/366 12/18639 0.166666666666667 8.48770491803279 0.0222840643788938 0.0997867294613702 GO:0004252 serine-type endopeptidase activity 8/366 176/18639 0.0454545454545455 2.31482861400894 0.0231982982722071 0.103122362392512 GO:0120015 sterol transfer activity 3/366 32/18639 0.09375 4.77433401639344 0.024454748531199 0.107919868518117 GO:0044389 ubiquitin-like protein ligase binding 12/366 322/18639 0.0372670807453416 1.89787190713777 0.0259195102645605 0.110720419972324 GO:0035401 histone H3Y41 kinase activity 6/366 115/18639 0.0521739130434783 2.65702066999287 0.0259794665711926 0.110720419972324 GO:0140801 histone H2AXY142 kinase activity 6/366 115/18639 0.0521739130434783 2.65702066999287 0.0259794665711926 0.110720419972324 GO:0008035 high-density lipoprotein particle binding 2/366 13/18639 0.153846153846154 7.83480453972257 0.0259983908966212 0.110720419972324 GO:0043560 insulin receptor substrate binding 2/366 13/18639 0.153846153846154 7.83480453972257 0.0259983908966212 0.110720419972324 GO:0019209 kinase activator activity 7/366 148/18639 0.0472972972972973 2.40867301727957 0.0270577106868083 0.11443156811296 GO:0019208 phosphatase regulator activity 6/366 117/18639 0.0512820512820513 2.61160151324086 0.0279675494276245 0.117463707596023 GO:0004879 nuclear receptor activity 4/366 59/18639 0.0677966101694915 3.45262572936927 0.0285705808894867 0.119174546312996 GO:0032036 myosin heavy chain binding 2/366 14/18639 0.142857142857143 7.2751756440281 0.0299436081613211 0.124052090954045 GO:0098531 ligand-modulated transcription factor activity 4/366 60/18639 0.0666666666666667 3.39508196721311 0.0301533884240913 0.124077118582916 GO:0051082 unfolded protein binding 6/366 121/18639 0.0495867768595041 2.52526757891885 0.0322391017743038 0.131769214634571 GO:0045296 cadherin binding 12/366 334/18639 0.0359281437125748 1.82968489251006 0.0330113977867278 0.133157337693645 GO:0004869 cysteine-type endopeptidase inhibitor activity 3/366 36/18639 0.0833333333333333 4.24385245901639 0.0332504127691969 0.133157337693645 GO:0005523 tropomyosin binding 2/366 15/18639 0.133333333333333 6.79016393442623 0.0341092687688155 0.133157337693645 GO:0031386 protein tag activity 2/366 15/18639 0.133333333333333 6.79016393442623 0.0341092687688155 0.133157337693645 GO:0051371 muscle alpha-actinin binding 2/366 15/18639 0.133333333333333 6.79016393442623 0.0341092687688155 0.133157337693645 GO:0120283 protein serine/threonine kinase binding 2/366 15/18639 0.133333333333333 6.79016393442623 0.0341092687688155 0.133157337693645 GO:0141047 molecular tag activity 2/366 15/18639 0.133333333333333 6.79016393442623 0.0341092687688155 0.133157337693645 GO:0031625 ubiquitin protein ligase binding 11/366 302/18639 0.0364238410596026 1.8549288893714 0.0369470693237075 0.143316975911706 GO:0008236 serine-type peptidase activity 8/366 194/18639 0.0412371134020619 2.10005070136894 0.0381415482397039 0.143788429298065 GO:0005024 transforming growth factor beta receptor activity 2/366 16/18639 0.125 6.36577868852459 0.0384852446232917 0.143788429298065 GO:0005159 insulin-like growth factor receptor binding 2/366 16/18639 0.125 6.36577868852459 0.0384852446232917 0.143788429298065 GO:0008142 oxysterol binding 2/366 16/18639 0.125 6.36577868852459 0.0384852446232917 0.143788429298065 GO:0016722 oxidoreductase activity, acting on metal ions 2/366 16/18639 0.125 6.36577868852459 0.0384852446232917 0.143788429298065 GO:0061809 NAD+ nucleosidase activity, cyclic ADP-ribose generating 2/366 16/18639 0.125 6.36577868852459 0.0384852446232917 0.143788429298065 GO:0017171 serine hydrolase activity 8/366 198/18639 0.0404040404040404 2.05762543467462 0.0421750845240116 0.156613576067823 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 2/366 17/18639 0.117647058823529 5.99132111861138 0.0430617184818899 0.15797943708115 GO:0008429 phosphatidylethanolamine binding 2/366 17/18639 0.117647058823529 5.99132111861138 0.0430617184818899 0.15797943708115 GO:1990841 promoter-specific chromatin binding 4/366 68/18639 0.0588235294117647 2.99566055930569 0.0446568495856885 0.162850427531044 GO:0042287 MHC protein binding 3/366 41/18639 0.0731707317073171 3.72630947620952 0.0462413729643462 0.167624976995755 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 2/366 18/18639 0.111111111111111 5.65846994535519 0.0478291757067947 0.170338994183848 GO:0034185 apolipoprotein binding 2/366 18/18639 0.111111111111111 5.65846994535519 0.0478291757067947 0.170338994183848 GO:1901611 phosphatidylglycerol binding 2/366 18/18639 0.111111111111111 5.65846994535519 0.0478291757067947 0.170338994183848 GO:0008307 structural constituent of muscle 3/366 42/18639 0.0714285714285714 3.63758782201405 0.049098810141908 0.173844042886174 GO:0008238 exopeptidase activity 5/366 102/18639 0.0490196078431373 2.49638379942141 0.0506324889972952 0.178238068204351 GO:0048156 tau protein binding 3/366 43/18639 0.0697674418604651 3.55299275638582 0.0520405553142715 0.18214194359995 GO:0042605 peptide antigen binding 3/366 45/18639 0.0666666666666667 3.39508196721311 0.0581727791967922 0.201334009146618 GO:0004713 protein tyrosine kinase activity 6/366 140/18639 0.0428571428571429 2.18255269320843 0.0581851980456564 0.201334009146618 GO:0030291 protein serine/threonine kinase inhibitor activity 3/366 46/18639 0.0652173913043478 3.32127583749109 0.0613610226820657 0.21112351871965 GO:0017022 myosin binding 4/366 76/18639 0.0526315789473684 2.68032786885246 0.0624354775040879 0.211432327904674 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 2/366 21/18639 0.0952380952380952 4.85011709601874 0.0631866727071441 0.211432327904674 GO:0010314 phosphatidylinositol-5-phosphate binding 2/366 21/18639 0.0952380952380952 4.85011709601874 0.0631866727071441 0.211432327904674 GO:0036122 BMP binding 2/366 21/18639 0.0952380952380952 4.85011709601874 0.0631866727071441 0.211432327904674 GO:0072542 protein phosphatase activator activity 2/366 21/18639 0.0952380952380952 4.85011709601874 0.0631866727071441 0.211432327904674 GO:0019903 protein phosphatase binding 6/366 144/18639 0.0416666666666667 2.1219262295082 0.0648783159341136 0.215906526797132 GO:0019887 protein kinase regulator activity 9/366 255/18639 0.0352941176470588 1.79739633558341 0.0652845498344012 0.216077667658426 GO:1902936 phosphatidylinositol bisphosphate binding 5/366 111/18639 0.045045045045045 2.29397430217102 0.0678107964614428 0.222565941131295 GO:0140693 molecular condensate scaffold activity 3/366 48/18639 0.0625 3.18288934426229 0.0679758046804939 0.222565941131295 GO:0005200 structural constituent of cytoskeleton 5/366 112/18639 0.0446428571428571 2.27349238875878 0.0698964711548647 0.227630753654078 GO:0005158 insulin receptor binding 2/366 23/18639 0.0869565217391304 4.42836778332145 0.0742183851110274 0.237889455434819 GO:0005212 structural constituent of eye lens 2/366 23/18639 0.0869565217391304 4.42836778332145 0.0742183851110274 0.237889455434819 GO:0017134 fibroblast growth factor binding 2/366 23/18639 0.0869565217391304 4.42836778332145 0.0742183851110274 0.237889455434819 GO:0001221 transcription coregulator binding 5/366 115/18639 0.0434782608695652 2.21418389166073 0.0763636255887135 0.24348402085616 GO:0030215 semaphorin receptor binding 2/366 24/18639 0.0833333333333333 4.24385245901639 0.0799478918699267 0.250970444065904 GO:0035035 histone acetyltransferase binding 2/366 24/18639 0.0833333333333333 4.24385245901639 0.0799478918699267 0.250970444065904 GO:0050699 WW domain binding 2/366 24/18639 0.0833333333333333 4.24385245901639 0.0799478918699267 0.250970444065904 GO:1990782 protein tyrosine kinase binding 5/366 117/18639 0.0427350427350427 2.17633459436738 0.0808488367272708 0.252497136240554 GO:0004860 protein kinase inhibitor activity 4/366 84/18639 0.0476190476190476 2.42505854800937 0.0833988656211208 0.259132189608482 GO:0001848 complement binding 2/366 25/18639 0.08 4.07409836065574 0.085809601030515 0.261389203646369 GO:0004709 MAP kinase kinase kinase activity 2/366 25/18639 0.08 4.07409836065574 0.085809601030515 0.261389203646369 GO:0019211 phosphatase activator activity 2/366 25/18639 0.08 4.07409836065574 0.085809601030515 0.261389203646369 GO:0004864 protein phosphatase inhibitor activity 3/366 53/18639 0.0566037735849057 2.88261676461491 0.0858421030037336 0.261389203646369 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 4/366 86/18639 0.0465116279069767 2.36866183759055 0.0891167631684825 0.270010491391074 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 3/366 54/18639 0.0555555555555556 2.8292349726776 0.0896321977974568 0.270227764646788 GO:0005160 transforming growth factor beta receptor binding 2/366 26/18639 0.0769230769230769 3.91740226986129 0.0917961452188463 0.272701719211109 GO:0008198 ferrous iron binding 2/366 26/18639 0.0769230769230769 3.91740226986129 0.0917961452188463 0.272701719211109 GO:0070412 R-SMAD binding 2/366 26/18639 0.0769230769230769 3.91740226986129 0.0917961452188463 0.272701719211109 GO:0098632 cell-cell adhesion mediator activity 3/366 55/18639 0.0545454545454545 2.77779433681073 0.0934911905706673 0.276389005133672 GO:0019212 phosphatase inhibitor activity 3/366 56/18639 0.0535714285714286 2.72819086651054 0.0974175838392091 0.286605355353035 GO:0001217 DNA-binding transcription repressor activity 9/366 278/18639 0.0323741007194245 1.64869088335889 0.09849031565793 0.288368279979228 GO:0019210 kinase inhibitor activity 4/366 90/18639 0.0444444444444444 2.26338797814208 0.101099250459236 0.294590638897964 GO:0051393 alpha-actinin binding 2/366 28/18639 0.0714285714285714 3.63758782201405 0.104115447489138 0.301934797718501 GO:0070888 E-box binding 3/366 59/18639 0.0508474576271186 2.58946929702695 0.109585908693763 0.316292978172995 GO:0004181 metallocarboxypeptidase activity 2/366 29/18639 0.0689655172413793 3.51215375918598 0.110434630021624 0.317239102279099 GO:0031210 phosphatidylcholine binding 2/366 30/18639 0.0666666666666667 3.39508196721311 0.116851484113403 0.332535298247956 GO:0048019 receptor antagonist activity 2/366 30/18639 0.0666666666666667 3.39508196721311 0.116851484113403 0.332535298247956 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 3/366 61/18639 0.0491803278688525 2.50456866433754 0.118006888130823 0.334261371496146 GO:0001664 G protein-coupled receptor binding 9/366 297/18639 0.0303030303030303 1.54321907600596 0.132095137528876 0.372434901643915 GO:0120013 lipid transfer activity 3/366 65/18639 0.0461538461538462 2.35044136191677 0.135533027421806 0.380366883409585 GO:0140416 transcription regulator inhibitor activity 2/366 33/18639 0.0606060606060606 3.08643815201192 0.136626649136807 0.381677198735393 GO:0030295 protein kinase activator activity 5/366 139/18639 0.0359712230215827 1.83187875928765 0.138860268681136 0.38614567866124 GO:0008235 metalloexopeptidase activity 3/366 66/18639 0.0454545454545455 2.31482861400894 0.140047792689496 0.38767775339956 GO:1901981 phosphatidylinositol phosphate binding 6/366 185/18639 0.0324324324324324 1.65166149756314 0.157542479954563 0.433480375140761 GO:0097110 scaffold protein binding 3/366 70/18639 0.0428571428571429 2.18255269320843 0.158591758254935 0.433480375140761 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 8/366 268/18639 0.0298507462686567 1.52018595546856 0.158729267087668 0.433480375140761 GO:0042805 actinin binding 2/366 37/18639 0.0540540540540541 2.75276916260523 0.164004966074453 0.445888501514919 GO:0005501 retinoid binding 2/366 38/18639 0.0526315789473684 2.68032786885246 0.170995003555646 0.4565698561596 GO:0019840 isoprenoid binding 2/366 38/18639 0.0526315789473684 2.68032786885246 0.170995003555646 0.4565698561596 GO:0019902 phosphatase binding 6/366 190/18639 0.0315789473684211 1.60819672131148 0.171559910724327 0.4565698561596 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 2/366 39/18639 0.0512820512820513 2.61160151324086 0.178033477097016 0.4565698561596 GO:0003680 minor groove of adenine-thymine-rich DNA binding 1/366 10/18639 0.1 5.09262295081967 0.179929007353537 0.4565698561596 GO:0004862 cAMP-dependent protein kinase inhibitor activity 1/366 10/18639 0.1 5.09262295081967 0.179929007353537 0.4565698561596 GO:0005381 iron ion transmembrane transporter activity 1/366 10/18639 0.1 5.09262295081967 0.179929007353537 0.4565698561596 GO:0008140 cAMP response element binding protein binding 1/366 10/18639 0.1 5.09262295081967 0.179929007353537 0.4565698561596 GO:0008239 dipeptidyl-peptidase activity 1/366 10/18639 0.1 5.09262295081967 0.179929007353537 0.4565698561596 GO:0008297 single-stranded DNA exodeoxyribonuclease activity 1/366 10/18639 0.1 5.09262295081967 0.179929007353537 0.4565698561596 GO:0015187 glycine transmembrane transporter activity 1/366 10/18639 0.1 5.09262295081967 0.179929007353537 0.4565698561596 GO:0015279 store-operated calcium channel activity 1/366 10/18639 0.1 5.09262295081967 0.179929007353537 0.4565698561596 GO:0015658 branched-chain amino acid transmembrane transporter activity 1/366 10/18639 0.1 5.09262295081967 0.179929007353537 0.4565698561596 GO:0016175 superoxide-generating NAD(P)H oxidase activity 1/366 10/18639 0.1 5.09262295081967 0.179929007353537 0.4565698561596 GO:0030957 Tat protein binding 1/366 10/18639 0.1 5.09262295081967 0.179929007353537 0.4565698561596 GO:0035374 chondroitin sulfate binding 1/366 10/18639 0.1 5.09262295081967 0.179929007353537 0.4565698561596 GO:0019003 GDP binding 3/366 75/18639 0.04 2.03704918032787 0.182743425986679 0.459187798166273 GO:0044183 protein folding chaperone 3/366 75/18639 0.04 2.03704918032787 0.182743425986679 0.459187798166273 GO:0050997 quaternary ammonium group binding 2/366 40/18639 0.05 2.54631147540984 0.18511580666198 0.459187798166273 GO:0098631 cell adhesion mediator activity 3/366 76/18639 0.0394736842105263 2.01024590163934 0.187687588253087 0.459187798166273 GO:0042169 SH2 domain binding 2/366 41/18639 0.0487804878048781 2.48420631747301 0.192237572492628 0.459187798166273 GO:0001851 complement component C3b binding 1/366 11/18639 0.0909090909090909 4.62965722801788 0.196040767690034 0.459187798166273 GO:0002162 dystroglycan binding 1/366 11/18639 0.0909090909090909 4.62965722801788 0.196040767690034 0.459187798166273 GO:0005114 type II transforming growth factor beta receptor binding 1/366 11/18639 0.0909090909090909 4.62965722801788 0.196040767690034 0.459187798166273 GO:0005225 volume-sensitive anion channel activity 1/366 11/18639 0.0909090909090909 4.62965722801788 0.196040767690034 0.459187798166273 GO:0008432 JUN kinase binding 1/366 11/18639 0.0909090909090909 4.62965722801788 0.196040767690034 0.459187798166273 GO:0008526 phosphatidylinositol transfer activity 1/366 11/18639 0.0909090909090909 4.62965722801788 0.196040767690034 0.459187798166273 GO:0010854 adenylate cyclase regulator activity 1/366 11/18639 0.0909090909090909 4.62965722801788 0.196040767690034 0.459187798166273 GO:0032050 clathrin heavy chain binding 1/366 11/18639 0.0909090909090909 4.62965722801788 0.196040767690034 0.459187798166273 GO:0034713 type I transforming growth factor beta receptor binding 1/366 11/18639 0.0909090909090909 4.62965722801788 0.196040767690034 0.459187798166273 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding 1/366 11/18639 0.0909090909090909 4.62965722801788 0.196040767690034 0.459187798166273 GO:0042608 T cell receptor binding 1/366 11/18639 0.0909090909090909 4.62965722801788 0.196040767690034 0.459187798166273 GO:0045294 alpha-catenin binding 1/366 11/18639 0.0909090909090909 4.62965722801788 0.196040767690034 0.459187798166273 GO:0048185 activin binding 1/366 11/18639 0.0909090909090909 4.62965722801788 0.196040767690034 0.459187798166273 GO:0050786 RAGE receptor binding 1/366 11/18639 0.0909090909090909 4.62965722801788 0.196040767690034 0.459187798166273 GO:0140031 phosphorylation-dependent protein binding 1/366 11/18639 0.0909090909090909 4.62965722801788 0.196040767690034 0.459187798166273 GO:0035198 miRNA binding 2/366 42/18639 0.0476190476190476 2.42505854800937 0.199394510610164 0.460745108789618 GO:0048487 beta-tubulin binding 2/366 42/18639 0.0476190476190476 2.42505854800937 0.199394510610164 0.460745108789618 GO:0003924 GTPase activity 9/366 331/18639 0.027190332326284 1.38470110445248 0.204966948852934 0.460745108789618 GO:0005525 GTP binding 10/366 378/18639 0.0264550264550265 1.34725474889409 0.211158303644957 0.460745108789618 GO:0004859 phospholipase inhibitor activity 1/366 12/18639 0.0833333333333333 4.24385245901639 0.211836831627411 0.460745108789618 GO:0004875 complement receptor activity 1/366 12/18639 0.0833333333333333 4.24385245901639 0.211836831627411 0.460745108789618 GO:0005165 neurotrophin receptor binding 1/366 12/18639 0.0833333333333333 4.24385245901639 0.211836831627411 0.460745108789618 GO:0008179 adenylate cyclase binding 1/366 12/18639 0.0833333333333333 4.24385245901639 0.211836831627411 0.460745108789618 GO:0008499 N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity 1/366 12/18639 0.0833333333333333 4.24385245901639 0.211836831627411 0.460745108789618 GO:0008603 cAMP-dependent protein kinase regulator activity 1/366 12/18639 0.0833333333333333 4.24385245901639 0.211836831627411 0.460745108789618 GO:0015368 calcium:monoatomic cation antiporter activity 1/366 12/18639 0.0833333333333333 4.24385245901639 0.211836831627411 0.460745108789618 GO:0031543 peptidyl-proline dioxygenase activity 1/366 12/18639 0.0833333333333333 4.24385245901639 0.211836831627411 0.460745108789618 GO:0035497 cAMP response element binding 1/366 12/18639 0.0833333333333333 4.24385245901639 0.211836831627411 0.460745108789618 GO:0070679 inositol 1,4,5 trisphosphate binding 1/366 12/18639 0.0833333333333333 4.24385245901639 0.211836831627411 0.460745108789618 GO:0097677 STAT family protein binding 1/366 12/18639 0.0833333333333333 4.24385245901639 0.211836831627411 0.460745108789618 GO:0140807 NAD+-protein-glutamate ADP-ribosyltransferase activity 1/366 12/18639 0.0833333333333333 4.24385245901639 0.211836831627411 0.460745108789618 GO:0140822 NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity 1/366 12/18639 0.0833333333333333 4.24385245901639 0.211836831627411 0.460745108789618 GO:0140844 NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity 1/366 12/18639 0.0833333333333333 4.24385245901639 0.211836831627411 0.460745108789618 GO:0140867 NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity 1/366 12/18639 0.0833333333333333 4.24385245901639 0.211836831627411 0.460745108789618 GO:1990459 transferrin receptor binding 1/366 12/18639 0.0833333333333333 4.24385245901639 0.211836831627411 0.460745108789618 GO:0001046 core promoter sequence-specific DNA binding 2/366 44/18639 0.0454545454545455 2.31482861400894 0.213797600485105 0.463354941976616 GO:0046915 transition metal ion transmembrane transporter activity 2/366 45/18639 0.0444444444444444 2.26338797814208 0.221035964265957 0.469815250544119 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 1/366 13/18639 0.0769230769230769 3.91740226986129 0.227323368354977 0.469815250544119 GO:0005542 folic acid binding 1/366 13/18639 0.0769230769230769 3.91740226986129 0.227323368354977 0.469815250544119 GO:0017154 semaphorin receptor activity 1/366 13/18639 0.0769230769230769 3.91740226986129 0.227323368354977 0.469815250544119 GO:0035325 Toll-like receptor binding 1/366 13/18639 0.0769230769230769 3.91740226986129 0.227323368354977 0.469815250544119 GO:0035673 oligopeptide transmembrane transporter activity 1/366 13/18639 0.0769230769230769 3.91740226986129 0.227323368354977 0.469815250544119 GO:0039706 co-receptor binding 1/366 13/18639 0.0769230769230769 3.91740226986129 0.227323368354977 0.469815250544119 GO:0045028 G protein-coupled purinergic nucleotide receptor activity 1/366 13/18639 0.0769230769230769 3.91740226986129 0.227323368354977 0.469815250544119 GO:0045159 myosin II binding 1/366 13/18639 0.0769230769230769 3.91740226986129 0.227323368354977 0.469815250544119 GO:0070123 transforming growth factor beta receptor activity, type III 1/366 13/18639 0.0769230769230769 3.91740226986129 0.227323368354977 0.469815250544119 GO:0097157 pre-mRNA intronic binding 1/366 13/18639 0.0769230769230769 3.91740226986129 0.227323368354977 0.469815250544119 GO:0140410 monoatomic cation:bicarbonate symporter activity 1/366 13/18639 0.0769230769230769 3.91740226986129 0.227323368354977 0.469815250544119 GO:0140806 NAD+-protein-aspartate ADP-ribosyltransferase activity 1/366 13/18639 0.0769230769230769 3.91740226986129 0.227323368354977 0.469815250544119 GO:0004180 carboxypeptidase activity 2/366 46/18639 0.0434782608695652 2.21418389166073 0.228293916156134 0.469815250544119 GO:0051117 ATPase binding 3/366 84/18639 0.0357142857142857 1.81879391100703 0.228350269558389 0.469815250544119 GO:0042826 histone deacetylase binding 4/366 127/18639 0.031496062992126 1.60397573254163 0.239626893493713 0.486507904843819 GO:0004065 arylsulfatase activity 1/366 14/18639 0.0714285714285714 3.63758782201405 0.242506426831412 0.486507904843819 GO:0019992 diacylglycerol binding 1/366 14/18639 0.0714285714285714 3.63758782201405 0.242506426831412 0.486507904843819 GO:0042043 neurexin family protein binding 1/366 14/18639 0.0714285714285714 3.63758782201405 0.242506426831412 0.486507904843819 GO:0043176 amine binding 1/366 14/18639 0.0714285714285714 3.63758782201405 0.242506426831412 0.486507904843819 GO:0070742 C2H2 zinc finger domain binding 1/366 14/18639 0.0714285714285714 3.63758782201405 0.242506426831412 0.486507904843819 GO:1901612 cardiolipin binding 1/366 14/18639 0.0714285714285714 3.63758782201405 0.242506426831412 0.486507904843819 GO:0032266 phosphatidylinositol-3-phosphate binding 2/366 48/18639 0.0416666666666667 2.1219262295082 0.242854520644534 0.486507904843819 GO:0060590 ATPase regulator activity 2/366 49/18639 0.0408163265306122 2.07862161257946 0.250150465389878 0.499480765319462 GO:0000774 adenyl-nucleotide exchange factor activity 1/366 15/18639 0.0666666666666667 3.39508196721311 0.257391938121597 0.502409263833502 GO:0004865 protein serine/threonine phosphatase inhibitor activity 1/366 15/18639 0.0666666666666667 3.39508196721311 0.257391938121597 0.502409263833502 GO:0005041 low-density lipoprotein particle receptor activity 1/366 15/18639 0.0666666666666667 3.39508196721311 0.257391938121597 0.502409263833502 GO:0008242 omega peptidase activity 1/366 15/18639 0.0666666666666667 3.39508196721311 0.257391938121597 0.502409263833502 GO:0031005 filamin binding 1/366 15/18639 0.0666666666666667 3.39508196721311 0.257391938121597 0.502409263833502 GO:0048531 beta-1,3-galactosyltransferase activity 1/366 15/18639 0.0666666666666667 3.39508196721311 0.257391938121597 0.502409263833502 GO:0050700 CARD domain binding 1/366 15/18639 0.0666666666666667 3.39508196721311 0.257391938121597 0.502409263833502 GO:0019001 guanyl nucleotide binding 10/366 400/18639 0.025 1.27315573770492 0.26254142994216 0.509196595015209 GO:0032561 guanyl ribonucleotide binding 10/366 400/18639 0.025 1.27315573770492 0.26254142994216 0.509196595015209 GO:0005048 signal sequence binding 2/366 51/18639 0.0392156862745098 1.99710703953713 0.264757803357841 0.509804618842056 GO:0005149 interleukin-1 receptor binding 1/366 16/18639 0.0625 3.18288934426229 0.271985717688151 0.509804618842056 GO:0005521 lamin binding 1/366 16/18639 0.0625 3.18288934426229 0.271985717688151 0.509804618842056 GO:0015562 efflux transmembrane transporter activity 1/366 16/18639 0.0625 3.18288934426229 0.271985717688151 0.509804618842056 GO:0019841 retinol binding 1/366 16/18639 0.0625 3.18288934426229 0.271985717688151 0.509804618842056 GO:0022858 alanine transmembrane transporter activity 1/366 16/18639 0.0625 3.18288934426229 0.271985717688151 0.509804618842056 GO:0031435 mitogen-activated protein kinase kinase kinase binding 1/366 16/18639 0.0625 3.18288934426229 0.271985717688151 0.509804618842056 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 1/366 16/18639 0.0625 3.18288934426229 0.271985717688151 0.509804618842056 GO:0055102 lipase inhibitor activity 1/366 16/18639 0.0625 3.18288934426229 0.271985717688151 0.509804618842056 GO:0005080 protein kinase C binding 2/366 52/18639 0.0384615384615385 1.95870113493064 0.272063220235908 0.509804618842056 GO:0030159 signaling receptor complex adaptor activity 2/366 52/18639 0.0384615384615385 1.95870113493064 0.272063220235908 0.509804618842056 GO:0140296 general transcription initiation factor binding 2/366 53/18639 0.0377358490566038 1.92174450974327 0.279366009146974 0.519577527466236 GO:0016410 N-acyltransferase activity 3/366 94/18639 0.0319148936170213 1.62530519707011 0.281131095637483 0.519577527466236 GO:0005096 GTPase activator activity 7/366 271/18639 0.025830258302583 1.31543766257335 0.284315462934404 0.519577527466236 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 1/366 17/18639 0.0588235294117647 2.99566055930569 0.286293467638542 0.519577527466236 GO:0008484 sulfuric ester hydrolase activity 1/366 17/18639 0.0588235294117647 2.99566055930569 0.286293467638542 0.519577527466236 GO:0019198 transmembrane receptor protein phosphatase activity 1/366 17/18639 0.0588235294117647 2.99566055930569 0.286293467638542 0.519577527466236 GO:0036041 long-chain fatty acid binding 1/366 17/18639 0.0588235294117647 2.99566055930569 0.286293467638542 0.519577527466236 GO:0045125 bioactive lipid receptor activity 1/366 17/18639 0.0588235294117647 2.99566055930569 0.286293467638542 0.519577527466236 GO:0046965 nuclear retinoid X receptor binding 1/366 17/18639 0.0588235294117647 2.99566055930569 0.286293467638542 0.519577527466236 GO:0070492 oligosaccharide binding 1/366 17/18639 0.0588235294117647 2.99566055930569 0.286293467638542 0.519577527466236 GO:0140463 chromatin-protein adaptor activity 2/366 54/18639 0.037037037037037 1.88615664845173 0.286663463429648 0.519577527466236 GO:0008017 microtubule binding 7/366 276/18639 0.0253623188405797 1.29160727013542 0.299765086106249 0.530131461934911 GO:0004706 JUN kinase kinase kinase activity 1/366 18/18639 0.0555555555555556 2.8292349726776 0.300320778928644 0.530131461934911 GO:0008409 5'-3' exonuclease activity 1/366 18/18639 0.0555555555555556 2.8292349726776 0.300320778928644 0.530131461934911 GO:0008525 phosphatidylcholine transporter activity 1/366 18/18639 0.0555555555555556 2.8292349726776 0.300320778928644 0.530131461934911 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 1/366 18/18639 0.0555555555555556 2.8292349726776 0.300320778928644 0.530131461934911 GO:0030228 lipoprotein particle receptor activity 1/366 18/18639 0.0555555555555556 2.8292349726776 0.300320778928644 0.530131461934911 GO:0035615 clathrin adaptor activity 1/366 18/18639 0.0555555555555556 2.8292349726776 0.300320778928644 0.530131461934911 GO:0070064 proline-rich region binding 1/366 18/18639 0.0555555555555556 2.8292349726776 0.300320778928644 0.530131461934911 GO:0098641 cadherin binding involved in cell-cell adhesion 1/366 18/18639 0.0555555555555556 2.8292349726776 0.300320778928644 0.530131461934911 GO:0030246 carbohydrate binding 7/366 280/18639 0.025 1.27315573770492 0.312251267496638 0.540312255129533 GO:0003756 protein disulfide isomerase activity 1/366 19/18639 0.0526315789473684 2.68032786885246 0.314073133523571 0.540312255129533 GO:0005346 purine ribonucleotide transmembrane transporter activity 1/366 19/18639 0.0526315789473684 2.68032786885246 0.314073133523571 0.540312255129533 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 1/366 19/18639 0.0526315789473684 2.68032786885246 0.314073133523571 0.540312255129533 GO:0016918 retinal binding 1/366 19/18639 0.0526315789473684 2.68032786885246 0.314073133523571 0.540312255129533 GO:0030506 ankyrin binding 1/366 19/18639 0.0526315789473684 2.68032786885246 0.314073133523571 0.540312255129533 GO:0042834 peptidoglycan binding 1/366 19/18639 0.0526315789473684 2.68032786885246 0.314073133523571 0.540312255129533 GO:0046624 sphingolipid transporter activity 1/366 19/18639 0.0526315789473684 2.68032786885246 0.314073133523571 0.540312255129533 GO:0070003 threonine-type peptidase activity 1/366 19/18639 0.0526315789473684 2.68032786885246 0.314073133523571 0.540312255129533 GO:0061980 regulatory RNA binding 2/366 58/18639 0.0344827586206897 1.75607687959299 0.315749471733041 0.541665995170202 GO:0035091 phosphatidylinositol binding 7/366 284/18639 0.0246478873239437 1.25522396675133 0.324833402575344 0.54802622821048 GO:0001614 purinergic nucleotide receptor activity 1/366 20/18639 0.05 2.54631147540984 0.327555906516609 0.54802622821048 GO:0001972 retinoic acid binding 1/366 20/18639 0.05 2.54631147540984 0.327555906516609 0.54802622821048 GO:0003899 DNA-directed 5'-3' RNA polymerase activity 1/366 20/18639 0.05 2.54631147540984 0.327555906516609 0.54802622821048 GO:0010851 cyclase regulator activity 1/366 20/18639 0.05 2.54631147540984 0.327555906516609 0.54802622821048 GO:0016408 C-acyltransferase activity 1/366 20/18639 0.05 2.54631147540984 0.327555906516609 0.54802622821048 GO:0016502 nucleotide receptor activity 1/366 20/18639 0.05 2.54631147540984 0.327555906516609 0.54802622821048 GO:0030742 GTP-dependent protein binding 1/366 20/18639 0.05 2.54631147540984 0.327555906516609 0.54802622821048 GO:0042288 MHC class I protein binding 1/366 20/18639 0.05 2.54631147540984 0.327555906516609 0.54802622821048 GO:0005253 monoatomic anion channel activity 3/366 103/18639 0.029126213592233 1.48328823810282 0.32947598706706 0.549728427736546 GO:0015026 coreceptor activity 2/366 61/18639 0.0327868852459016 1.6697124428917 0.337390557581995 0.559384340264455 GO:0001846 opsonin binding 1/366 21/18639 0.0476190476190476 2.42505854800937 0.340774368207082 0.559384340264455 GO:0009975 cyclase activity 1/366 21/18639 0.0476190476190476 2.42505854800937 0.340774368207082 0.559384340264455 GO:0051010 microtubule plus-end binding 1/366 21/18639 0.0476190476190476 2.42505854800937 0.340774368207082 0.559384340264455 GO:0061891 calcium ion sensor activity 1/366 21/18639 0.0476190476190476 2.42505854800937 0.340774368207082 0.559384340264455 GO:0140312 cargo adaptor activity 1/366 21/18639 0.0476190476190476 2.42505854800937 0.340774368207082 0.559384340264455 GO:0015631 tubulin binding 9/366 385/18639 0.0233766233766234 1.1904832872046 0.344997085651537 0.564793616026306 GO:0005243 gap junction channel activity 1/366 22/18639 0.0454545454545455 2.31482861400894 0.353733686137913 0.571415954530475 GO:0034062 5'-3' RNA polymerase activity 1/366 22/18639 0.0454545454545455 2.31482861400894 0.353733686137913 0.571415954530475 GO:0061133 endopeptidase activator activity 1/366 22/18639 0.0454545454545455 2.31482861400894 0.353733686137913 0.571415954530475 GO:0097747 RNA polymerase activity 1/366 22/18639 0.0454545454545455 2.31482861400894 0.353733686137913 0.571415954530475 GO:0140784 metal ion sensor activity 1/366 22/18639 0.0454545454545455 2.31482861400894 0.353733686137913 0.571415954530475 GO:0000295 adenine nucleotide transmembrane transporter activity 1/366 23/18639 0.0434782608695652 2.21418389166073 0.36643892709368 0.584191902094375 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 1/366 23/18639 0.0434782608695652 2.21418389166073 0.36643892709368 0.584191902094375 GO:0016849 phosphorus-oxygen lyase activity 1/366 23/18639 0.0434782608695652 2.21418389166073 0.36643892709368 0.584191902094375 GO:0031681 G-protein beta-subunit binding 1/366 23/18639 0.0434782608695652 2.21418389166073 0.36643892709368 0.584191902094375 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 1/366 23/18639 0.0434782608695652 2.21418389166073 0.36643892709368 0.584191902094375 GO:0001091 RNA polymerase II general transcription initiation factor binding 1/366 24/18639 0.0416666666666667 2.1219262295082 0.378895059059931 0.597790391107507 GO:0005540 hyaluronic acid binding 1/366 24/18639 0.0416666666666667 2.1219262295082 0.378895059059931 0.597790391107507 GO:0019957 C-C chemokine binding 1/366 24/18639 0.0416666666666667 2.1219262295082 0.378895059059931 0.597790391107507 GO:0070300 phosphatidic acid binding 1/366 24/18639 0.0416666666666667 2.1219262295082 0.378895059059931 0.597790391107507 GO:0005537 D-mannose binding 1/366 25/18639 0.04 2.03704918032787 0.391106953144489 0.610728549910241 GO:0008139 nuclear localization sequence binding 1/366 25/18639 0.04 2.03704918032787 0.391106953144489 0.610728549910241 GO:0016895 DNA exonuclease activity, producing 5'-phosphomonoesters 1/366 25/18639 0.04 2.03704918032787 0.391106953144489 0.610728549910241 GO:0042974 nuclear retinoic acid receptor binding 1/366 25/18639 0.04 2.03704918032787 0.391106953144489 0.610728549910241 GO:0004529 DNA exonuclease activity 1/366 26/18639 0.0384615384615385 1.95870113493064 0.403079385461515 0.61677222549262 GO:0008157 protein phosphatase 1 binding 1/366 26/18639 0.0384615384615385 1.95870113493064 0.403079385461515 0.61677222549262 GO:0015216 purine nucleotide transmembrane transporter activity 1/366 26/18639 0.0384615384615385 1.95870113493064 0.403079385461515 0.61677222549262 GO:0030247 polysaccharide binding 1/366 26/18639 0.0384615384615385 1.95870113493064 0.403079385461515 0.61677222549262 GO:0030507 spectrin binding 1/366 26/18639 0.0384615384615385 1.95870113493064 0.403079385461515 0.61677222549262 GO:0052742 phosphatidylinositol kinase activity 1/366 26/18639 0.0384615384615385 1.95870113493064 0.403079385461515 0.61677222549262 GO:0070006 metalloaminopeptidase activity 1/366 26/18639 0.0384615384615385 1.95870113493064 0.403079385461515 0.61677222549262 GO:0120014 phospholipid transfer activity 1/366 26/18639 0.0384615384615385 1.95870113493064 0.403079385461515 0.61677222549262 GO:0001671 ATPase activator activity 1/366 27/18639 0.037037037037037 1.88615664845173 0.414817038979008 0.626857510516664 GO:0005044 scavenger receptor activity 1/366 27/18639 0.037037037037037 1.88615664845173 0.414817038979008 0.626857510516664 GO:0005104 fibroblast growth factor receptor binding 1/366 27/18639 0.037037037037037 1.88615664845173 0.414817038979008 0.626857510516664 GO:0005385 zinc ion transmembrane transporter activity 1/366 27/18639 0.037037037037037 1.88615664845173 0.414817038979008 0.626857510516664 GO:0035255 ionotropic glutamate receptor binding 1/366 27/18639 0.037037037037037 1.88615664845173 0.414817038979008 0.626857510516664 GO:0043539 protein serine/threonine kinase activator activity 2/366 73/18639 0.0273972602739726 1.39523916460813 0.421405789282624 0.635237934834451 GO:0045499 chemorepellent activity 1/366 28/18639 0.0357142857142857 1.81879391100703 0.426324505330484 0.63791553746011 GO:0046875 ephrin receptor binding 1/366 28/18639 0.0357142857142857 1.81879391100703 0.426324505330484 0.63791553746011 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 1/366 28/18639 0.0357142857142857 1.81879391100703 0.426324505330484 0.63791553746011 GO:0008528 G protein-coupled peptide receptor activity 3/366 122/18639 0.0245901639344262 1.25228433216877 0.430496071014004 0.642578694234139 GO:0003785 actin monomer binding 1/366 29/18639 0.0344827586206897 1.75607687959299 0.437606286591515 0.648423913708595 GO:0035250 UDP-galactosyltransferase activity 1/366 29/18639 0.0344827586206897 1.75607687959299 0.437606286591515 0.648423913708595 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 1/366 29/18639 0.0344827586206897 1.75607687959299 0.437606286591515 0.648423913708595 GO:0003823 antigen binding 4/366 174/18639 0.0229885057471264 1.17071791972866 0.446601164393238 0.658405010569332 GO:0015215 nucleotide transmembrane transporter activity 1/366 30/18639 0.0333333333333333 1.69754098360656 0.448666797021794 0.658405010569332 GO:0035925 mRNA 3'-UTR AU-rich region binding 1/366 30/18639 0.0333333333333333 1.69754098360656 0.448666797021794 0.658405010569332 GO:0051721 protein phosphatase 2A binding 1/366 30/18639 0.0333333333333333 1.69754098360656 0.448666797021794 0.658405010569332 GO:0070273 phosphatidylinositol-4-phosphate binding 1/366 31/18639 0.032258064516129 1.6427815970386 0.459510364773421 0.670584084627387 GO:0072349 modified amino acid transmembrane transporter activity 1/366 31/18639 0.032258064516129 1.6427815970386 0.459510364773421 0.670584084627387 GO:0001653 peptide receptor activity 3/366 128/18639 0.0234375 1.19358350409836 0.461370659209976 0.670584084627387 GO:0031490 chromatin DNA binding 3/366 128/18639 0.0234375 1.19358350409836 0.461370659209976 0.670584084627387 GO:0005319 lipid transporter activity 4/366 178/18639 0.0224719101123595 1.14440965186959 0.463899078001493 0.672653663102165 GO:0035591 signaling adaptor activity 3/366 129/18639 0.0232558139534884 1.18433091879527 0.466447575673519 0.673684732333445 GO:0048306 calcium-dependent protein binding 2/366 80/18639 0.025 1.27315573770492 0.467857063939783 0.673684732333445 GO:0008378 galactosyltransferase activity 1/366 32/18639 0.03125 1.59144467213115 0.470141233566033 0.673684732333445 GO:0015106 bicarbonate transmembrane transporter activity 1/366 32/18639 0.03125 1.59144467213115 0.470141233566033 0.673684732333445 GO:0051059 NF-kappaB binding 1/366 32/18639 0.03125 1.59144467213115 0.470141233566033 0.673684732333445 GO:0030971 receptor tyrosine kinase binding 2/366 81/18639 0.0246913580246914 1.25743776563449 0.474311849831626 0.678065531801549 GO:0019956 chemokine binding 1/366 33/18639 0.0303030303030303 1.54321907600596 0.480563564329447 0.683792548309891 GO:0030296 protein tyrosine kinase activator activity 1/366 33/18639 0.0303030303030303 1.54321907600596 0.480563564329447 0.683792548309891 GO:0005254 chloride channel activity 2/366 83/18639 0.0240963855421687 1.22713806043848 0.487078285691316 0.689838781362818 GO:0030165 PDZ domain binding 2/366 83/18639 0.0240963855421687 1.22713806043848 0.487078285691316 0.689838781362818 GO:0015035 protein-disulfide reductase activity 1/366 34/18639 0.0294117647058824 1.49783027965284 0.490781436814421 0.692884353657876 GO:0051087 protein-folding chaperone binding 3/366 134/18639 0.0223880597014925 1.14013946660142 0.491504172052878 0.692884353657876 GO:0030695 GTPase regulator activity 10/366 489/18639 0.0204498977505112 1.04143618626169 0.49319414004822 0.693661042238721 GO:0060589 nucleoside-triphosphatase regulator activity 10/366 490/18639 0.0204081632653061 1.03931080628973 0.495789748751044 0.695704970021626 GO:0044325 transmembrane transporter binding 3/366 136/18639 0.0220588235294118 1.12337270973963 0.50136461456127 0.701910460385779 GO:0050660 flavin adenine dinucleotide binding 2/366 86/18639 0.0232558139534884 1.18433091879527 0.505861332603737 0.706581540265312 GO:0004190 aspartic-type endopeptidase activity 1/366 36/18639 0.0277777777777778 1.4146174863388 0.510619729503227 0.708354021110399 GO:0016409 palmitoyltransferase activity 1/366 36/18639 0.0277777777777778 1.4146174863388 0.510619729503227 0.708354021110399 GO:0045505 dynein intermediate chain binding 1/366 36/18639 0.0277777777777778 1.4146174863388 0.510619729503227 0.708354021110399 GO:0004197 cysteine-type endopeptidase activity 2/366 88/18639 0.0227272727272727 1.15741430700447 0.518133085489969 0.716812175751437 GO:0022829 wide pore channel activity 1/366 37/18639 0.027027027027027 1.37638458130261 0.520247917376249 0.716812175751437 GO:0070001 aspartic-type peptidase activity 1/366 37/18639 0.027027027027027 1.37638458130261 0.520247917376249 0.716812175751437 GO:0005109 frizzled binding 1/366 38/18639 0.0263157894736842 1.34016393442623 0.529687185317346 0.72653039607717 GO:0042887 amide transmembrane transporter activity 1/366 38/18639 0.0263157894736842 1.34016393442623 0.529687185317346 0.72653039607717 GO:0000217 DNA secondary structure binding 1/366 39/18639 0.0256410256410256 1.30580075662043 0.538941230270512 0.737562267943241 GO:0141003 histone H2AX kinase activity 7/366 354/18639 0.019774011299435 1.0070158377327 0.545768764760764 0.741645176246868 GO:0051219 phosphoprotein binding 2/366 93/18639 0.021505376344086 1.09518773135907 0.547913608206997 0.741645176246868 GO:0004177 aminopeptidase activity 1/366 40/18639 0.025 1.27315573770492 0.548013677029705 0.741645176246868 GO:0015036 disulfide oxidoreductase activity 1/366 40/18639 0.025 1.27315573770492 0.548013677029705 0.741645176246868 GO:0071949 FAD binding 1/366 40/18639 0.025 1.27315573770492 0.548013677029705 0.741645176246868 GO:0015085 calcium ion transmembrane transporter activity 3/366 147/18639 0.0204081632653061 1.03931080628973 0.553762549146551 0.743765395839184 GO:0140996 histone H3 kinase activity 7/366 357/18639 0.0196078431372549 0.998553519768563 0.55473182404757 0.743765395839184 GO:0001727 lipid kinase activity 1/366 41/18639 0.024390243902439 1.24210315873651 0.556908079643132 0.743765395839184 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 1/366 41/18639 0.024390243902439 1.24210315873651 0.556908079643132 0.743765395839184 GO:0015175 neutral L-amino acid transmembrane transporter activity 1/366 41/18639 0.024390243902439 1.24210315873651 0.556908079643132 0.743765395839184 GO:0140828 metal cation:monoatomic cation antiporter activity 1/366 41/18639 0.024390243902439 1.24210315873651 0.556908079643132 0.743765395839184 GO:0008509 monoatomic anion transmembrane transporter activity 3/366 149/18639 0.0201342281879195 1.02536032566839 0.562933776716451 0.74943927461223 GO:0035173 histone kinase activity 7/366 360/18639 0.0194444444444444 0.990232240437159 0.563617713911989 0.74943927461223 GO:0019894 kinesin binding 1/366 42/18639 0.0238095238095238 1.21252927400468 0.565627922790278 0.75047364919233 GO:0003714 transcription corepressor activity 4/366 204/18639 0.0196078431372549 0.998553519768563 0.570677969295417 0.755528007175889 GO:0008200 ion channel inhibitor activity 1/366 43/18639 0.0232558139534884 1.18433091879527 0.574176623132202 0.756869185037903 GO:0008375 acetylglucosaminyltransferase activity 1/366 43/18639 0.0232558139534884 1.18433091879527 0.574176623132202 0.756869185037903 GO:0001223 transcription coactivator binding 1/366 44/18639 0.0227272727272727 1.15741430700447 0.582557530635623 0.76296244334859 GO:0016248 channel inhibitor activity 1/366 44/18639 0.0227272727272727 1.15741430700447 0.582557530635623 0.76296244334859 GO:0043014 alpha-tubulin binding 1/366 44/18639 0.0227272727272727 1.15741430700447 0.582557530635623 0.76296244334859 GO:0141110 transporter inhibitor activity 1/366 45/18639 0.0222222222222222 1.13169398907104 0.590773929871297 0.772062925518498 GO:0030276 clathrin binding 1/366 46/18639 0.0217391304347826 1.10709194583036 0.59882904128719 0.78091410309186 GO:0001784 phosphotyrosine residue binding 1/366 47/18639 0.0212765957446809 1.08353679804674 0.606726022456925 0.789521683068947 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 1/366 48/18639 0.0208333333333333 1.0609631147541 0.614467969303997 0.796193602779009 GO:0038187 pattern recognition receptor activity 1/366 48/18639 0.0208333333333333 1.0609631147541 0.614467969303997 0.796193602779009 GO:0001222 transcription corepressor binding 1/366 49/18639 0.0204081632653061 1.03931080628973 0.622057917302208 0.800916007689312 GO:0016763 pentosyltransferase activity 1/366 49/18639 0.0204081632653061 1.03931080628973 0.622057917302208 0.800916007689312 GO:0035254 glutamate receptor binding 1/366 49/18639 0.0204081632653061 1.03931080628973 0.622057917302208 0.800916007689312 GO:0015605 organophosphate ester transmembrane transporter activity 1/366 50/18639 0.02 1.01852459016393 0.629498842652794 0.808786487712134 GO:0030544 Hsp70 protein binding 1/366 51/18639 0.0196078431372549 0.998553519768563 0.636793663438693 0.816436507440345 GO:0005246 calcium channel regulator activity 1/366 53/18639 0.0188679245283019 0.960872254871636 0.650956379825806 0.827625125916317 GO:0016860 intramolecular oxidoreductase activity 1/366 53/18639 0.0188679245283019 0.960872254871636 0.650956379825806 0.827625125916317 GO:0051018 protein kinase A binding 1/366 53/18639 0.0188679245283019 0.960872254871636 0.650956379825806 0.827625125916317 GO:1901505 carbohydrate derivative transmembrane transporter activity 1/366 53/18639 0.0188679245283019 0.960872254871636 0.650956379825806 0.827625125916317 GO:0003925 G protein activity 1/366 54/18639 0.0185185185185185 0.943078324225865 0.657829831078564 0.834621598180928 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 4/366 229/18639 0.0174672489082969 0.889541126780729 0.661210226463734 0.837166378204603 GO:0015932 nucleobase-containing compound transmembrane transporter activity 1/366 57/18639 0.0175438596491228 0.89344262295082 0.677650762695045 0.856201897264072 GO:0015459 potassium channel regulator activity 1/366 59/18639 0.0169491525423729 0.863156432342317 0.690224332757209 0.863211481123109 GO:0036002 pre-mRNA binding 1/366 59/18639 0.0169491525423729 0.863156432342317 0.690224332757209 0.863211481123109 GO:0045309 protein phosphorylated amino acid binding 1/366 59/18639 0.0169491525423729 0.863156432342317 0.690224332757209 0.863211481123109 GO:0070063 RNA polymerase binding 1/366 59/18639 0.0169491525423729 0.863156432342317 0.690224332757209 0.863211481123109 GO:0015108 chloride transmembrane transporter activity 2/366 121/18639 0.0165289256198347 0.841755859639615 0.690285700011419 0.863211481123109 GO:0001098 basal transcription machinery binding 1/366 60/18639 0.0166666666666667 0.848770491803279 0.696326479916028 0.863671743928434 GO:0001099 basal RNA polymerase II transcription machinery binding 1/366 60/18639 0.0166666666666667 0.848770491803279 0.696326479916028 0.863671743928434 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 1/366 60/18639 0.0166666666666667 0.848770491803279 0.696326479916028 0.863671743928434 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 1/366 60/18639 0.0166666666666667 0.848770491803279 0.696326479916028 0.863671743928434 GO:0015179 L-amino acid transmembrane transporter activity 1/366 62/18639 0.0161290322580645 0.821390798519302 0.708173477725796 0.876580585233759 GO:1901682 sulfur compound transmembrane transporter activity 1/366 63/18639 0.0158730158730159 0.808352849336456 0.713922980183263 0.881904857873442 GO:0004536 DNA nuclease activity 1/366 64/18639 0.015625 0.795722336065574 0.719559510612468 0.887068303568812 GO:0019843 rRNA binding 1/366 65/18639 0.0153846153846154 0.783480453972257 0.725085282839431 0.892074620705482 GO:0016798 hydrolase activity, acting on glycosyl bonds 2/366 130/18639 0.0153846153846154 0.783480453972257 0.727478183173928 0.893214140227665 GO:0005262 calcium channel activity 2/366 131/18639 0.0152671755725191 0.777499687148042 0.731368738855869 0.894384662576756 GO:0031072 heat shock protein binding 2/366 131/18639 0.0152671755725191 0.777499687148042 0.731368738855869 0.894384662576756 GO:0005179 hormone activity 2/366 132/18639 0.0151515151515152 0.771609538002981 0.735212117079175 0.896220468471106 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 1/366 67/18639 0.0149253731343284 0.76009297773428 0.735813192505014 0.896220468471106 GO:0005548 phospholipid transporter activity 1/366 68/18639 0.0147058823529412 0.748915139826422 0.741019544623426 0.898965941584993 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 1/366 68/18639 0.0147058823529412 0.748915139826422 0.741019544623426 0.898965941584993 GO:0002039 p53 binding 1/366 69/18639 0.0144927536231884 0.738061297220242 0.746123569536884 0.900189644012183 GO:0008080 N-acetyltransferase activity 1/366 69/18639 0.0144927536231884 0.738061297220242 0.746123569536884 0.900189644012183 GO:0015297 antiporter activity 2/366 135/18639 0.0148148148148148 0.754462659380692 0.746462676890234 0.900189644012183 GO:0016779 nucleotidyltransferase activity 2/366 136/18639 0.0147058823529412 0.748915139826422 0.750120856924995 0.902813442425537 GO:0016922 nuclear receptor binding 2/366 137/18639 0.0145985401459854 0.743448605959076 0.753733636018063 0.905372355690336 GO:0140299 molecular sensor activity 1/366 71/18639 0.0140845070422535 0.717270838143616 0.756032621608795 0.906346194015268 GO:0003712 transcription coregulator activity 8/366 495/18639 0.0161616161616162 0.823050173869846 0.759689238642652 0.908940562541011 GO:0004521 RNA endonuclease activity 1/366 73/18639 0.0136986301369863 0.697619582304065 0.765555928910551 0.914163844522599 GO:0048029 monosaccharide binding 1/366 74/18639 0.0135135135135135 0.688192290651307 0.770177631486159 0.917882930675285 GO:0008514 organic anion transmembrane transporter activity 4/366 269/18639 0.0148698884758364 0.757267353281736 0.777250825037579 0.924503422749776 GO:0051540 metal cluster binding 1/366 77/18639 0.012987012987013 0.661379604002555 0.783504636983185 0.930125387763663 GO:0019842 vitamin binding 2/366 150/18639 0.0133333333333333 0.679016393442623 0.796738654936464 0.943995799331336 GO:0015101 organic cation transmembrane transporter activity 1/366 81/18639 0.0123456790123457 0.628718882817243 0.800082683249791 0.946117192425481 GO:0005506 iron ion binding 2/366 154/18639 0.012987012987013 0.661379604002555 0.808569182611535 0.95369285539173 GO:0031267 small GTPase binding 4/366 283/18639 0.0141342756183746 0.719805364073452 0.809621028304638 0.95369285539173 GO:0004527 exonuclease activity 1/366 84/18639 0.0119047619047619 0.606264637002342 0.811679832217603 0.95427223517475 GO:0008081 phosphoric diester hydrolase activity 1/366 87/18639 0.0114942528735632 0.58535895986433 0.822605965035717 0.965254398278904 GO:0099106 ion channel regulator activity 2/366 160/18639 0.0125 0.636577868852459 0.825167441494008 0.965639813557719 GO:0016651 oxidoreductase activity, acting on NAD(P)H 1/366 88/18639 0.0113636363636364 0.578707153502235 0.826105653306357 0.965639813557719 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 1/366 89/18639 0.0112359550561798 0.572204825934795 0.829536483498254 0.965942100287642 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 1/366 89/18639 0.0112359550561798 0.572204825934795 0.829536483498254 0.965942100287642 GO:0005085 guanyl-nucleotide exchange factor activity 3/366 230/18639 0.0130434782608696 0.664255167498218 0.832748858520979 0.966163775875008 GO:0140793 histone H2AXY142 phosphatase activity 1/366 90/18639 0.0111111111111111 0.565846994535519 0.8328998067888 0.966163775875008 GO:0015103 inorganic anion transmembrane transporter activity 2/366 165/18639 0.0121212121212121 0.617287630402385 0.838000725310914 0.970232778924614 GO:0051213 dioxygenase activity 1/366 93/18639 0.010752688172043 0.547593865679535 0.842597853478837 0.973704160851256 GO:0016247 channel regulator activity 2/366 168/18639 0.0119047619047619 0.606264637002342 0.845286417276073 0.974961038108198 GO:0141108 transporter regulator activity 2/366 170/18639 0.0117647058823529 0.599132111861138 0.84997722948992 0.978518209374974 GO:0016407 acetyltransferase activity 1/366 96/18639 0.0104166666666667 0.530481557377049 0.851734500001878 0.97869115188895 GO:0004725 protein tyrosine phosphatase activity 1/366 98/18639 0.0102040816326531 0.519655403144864 0.857529793855715 0.983494622331696 GO:0043130 ubiquitin binding 1/366 100/18639 0.01 0.509262295081967 0.863099160211182 0.988021407083853 GO:0043021 ribonucleoprotein complex binding 2/366 177/18639 0.0112994350282486 0.575437621561545 0.865393969987953 0.988789733063158 GO:0015171 amino acid transmembrane transporter activity 1/366 102/18639 0.00980392156862745 0.499276759884282 0.868451383582416 0.989567264021069 GO:0051020 GTPase binding 4/366 315/18639 0.0126984126984127 0.646682279469165 0.869324279558739 0.989567264021069 GO:0000149 SNARE binding 1/366 106/18639 0.00943396226415094 0.480436127435818 0.878537849315985 0.998189459390737 GO:0003713 transcription coactivator activity 3/366 256/18639 0.01171875 0.59679175204918 0.881780096210894 0.999953254923288 GO:0008234 cysteine-type peptidase activity 2/366 187/18639 0.0106951871657754 0.544665556237398 0.884909695825724 0.999953254923288 GO:0004620 phospholipase activity 1/366 109/18639 0.00917431192660551 0.467213114754098 0.885593151724343 0.999953254923288 GO:0043022 ribosome binding 1/366 112/18639 0.00892857142857143 0.454698477751756 0.892239691387433 0.999953254923288 GO:0017124 SH3 domain binding 1/366 115/18639 0.00869565217391304 0.442836778332145 0.898501089656593 0.999953254923288 GO:0009055 electron transfer activity 1/366 116/18639 0.00862068965517241 0.439019219898248 0.900506520513087 0.999953254923288 GO:0015294 solute:monoatomic cation symporter activity 1/366 116/18639 0.00862068965517241 0.439019219898248 0.900506520513087 0.999953254923288 GO:0016829 lyase activity 2/366 200/18639 0.01 0.509262295081967 0.906375981794141 0.999953254923288 GO:0032182 ubiquitin-like protein binding 1/366 120/18639 0.00833333333333333 0.424385245901639 0.908140759437394 0.999953254923288 GO:0004540 RNA nuclease activity 1/366 121/18639 0.00826446280991736 0.420877929819808 0.909956218265944 0.999953254923288 GO:0004518 nuclease activity 2/366 209/18639 0.00956937799043062 0.487332339791356 0.918982626873594 0.999953254923288 GO:0004519 endonuclease activity 1/366 127/18639 0.0078740157480315 0.400993933135407 0.920121656365705 0.999953254923288 GO:0015291 secondary active transmembrane transporter activity 3/366 287/18639 0.0104529616724739 0.532329925172788 0.923247485225678 0.999953254923288 GO:0016298 lipase activity 1/366 130/18639 0.00769230769230769 0.391740226986129 0.924766662946682 0.999953254923288 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 1/366 130/18639 0.00769230769230769 0.391740226986129 0.924766662946682 0.999953254923288 GO:0004674 protein serine/threonine kinase activity 5/366 433/18639 0.0115473441108545 0.5880626963995 0.929989639914689 0.999953254923288 GO:0140789 histone phosphatase activity 1/366 136/18639 0.00735294117647059 0.374457569913211 0.933264011881284 0.999953254923288 GO:0140767 enzyme-substrate adaptor activity 1/366 139/18639 0.00719424460431655 0.36637575185753 0.937146627326131 0.999953254923288 GO:0020037 heme binding 1/366 142/18639 0.00704225352112676 0.358635419071808 0.940803938316622 0.999953254923288 GO:0005216 monoatomic ion channel activity 5/366 448/18639 0.0111607142857143 0.568373097189696 0.941712525479724 0.999953254923288 GO:0000287 magnesium ion binding 2/366 230/18639 0.00869565217391304 0.442836778332145 0.942470136633543 0.999953254923288 GO:0046873 metal ion transmembrane transporter activity 5/366 450/18639 0.0111111111111111 0.565846994535519 0.943134709624217 0.999953254923288 GO:0008194 UDP-glycosyltransferase activity 1/366 145/18639 0.00689655172413793 0.351215375918598 0.944248985316829 0.999953254923288 GO:0015293 symporter activity 1/366 146/18639 0.00684931506849315 0.348809791152032 0.945352309171811 0.999953254923288 GO:0046906 tetrapyrrole binding 1/366 152/18639 0.00657894736842105 0.335040983606557 0.951529657129123 0.999953254923288 GO:0015081 sodium ion transmembrane transporter activity 1/366 164/18639 0.00609756097560976 0.310525789684126 0.961872933414682 0.999953254923288 GO:0015399 primary active transmembrane transporter activity 1/366 166/18639 0.00602409638554217 0.306784515109619 0.963368646898979 0.999953254923288 GO:0003730 mRNA 3'-UTR binding 2/366 262/18639 0.00763358778625954 0.388749843574021 0.966245915125643 0.999953254923288 GO:0005244 voltage-gated monoatomic ion channel activity 1/366 173/18639 0.00578034682080925 0.294371268833507 0.968157549754313 0.999953254923288 GO:0140030 modification-dependent protein binding 1/366 173/18639 0.00578034682080925 0.294371268833507 0.968157549754313 0.999953254923288 GO:0016757 glycosyltransferase activity 2/366 267/18639 0.00749063670411985 0.38146988395653 0.96897860040626 0.999953254923288 GO:0004721 phosphoprotein phosphatase activity 1/366 175/18639 0.00571428571428571 0.291007025761124 0.969407322353925 0.999953254923288 GO:0022832 voltage-gated channel activity 1/366 175/18639 0.00571428571428571 0.291007025761124 0.969407322353925 0.999953254923288 GO:0016853 isomerase activity 1/366 180/18639 0.00555555555555556 0.28292349726776 0.972321873169779 0.999953254923288 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 1/366 181/18639 0.00552486187845304 0.281360384023186 0.972870667493408 0.999953254923288 GO:0046943 carboxylic acid transmembrane transporter activity 1/366 188/18639 0.00531914893617021 0.270884199511685 0.97642006126725 0.999953254923288 GO:0140597 protein carrier chaperone 1/366 188/18639 0.00531914893617021 0.270884199511685 0.97642006126725 0.999953254923288 GO:0005342 organic acid transmembrane transporter activity 1/366 189/18639 0.00529100529100529 0.269450949778819 0.976887800553803 0.999953254923288 GO:0016758 hexosyltransferase activity 1/366 197/18639 0.0050761421319797 0.258508779229425 0.980311485193292 0.999953254923288 GO:0022804 active transmembrane transporter activity 4/366 457/18639 0.0087527352297593 0.445743803135201 0.980345697304972 0.999953254923288 GO:0005261 monoatomic cation channel activity 2/366 341/18639 0.00586510263929619 0.298687563097928 0.99135930269708 0.999953254923288 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 1/366 243/18639 0.00411522633744856 0.209572960939081 0.992179093128531 0.999953254923288 GO:0004676 3-phosphoinositide-dependent protein kinase activity 1/366 245/18639 0.00408163265306122 0.207862161257946 0.992487209352795 0.999953254923288 GO:0004711 ribosomal protein S6 kinase activity 1/366 245/18639 0.00408163265306122 0.207862161257946 0.992487209352795 0.999953254923288 GO:0035175 histone H3S10 kinase activity 1/366 245/18639 0.00408163265306122 0.207862161257946 0.992487209352795 0.999953254923288 GO:0035979 histone H2AXS139 kinase activity 1/366 245/18639 0.00408163265306122 0.207862161257946 0.992487209352795 0.999953254923288 GO:0044022 histone H3S28 kinase activity 1/366 245/18639 0.00408163265306122 0.207862161257946 0.992487209352795 0.999953254923288 GO:0044023 histone H4S1 kinase activity 1/366 245/18639 0.00408163265306122 0.207862161257946 0.992487209352795 0.999953254923288 GO:0044024 histone H2AS1 kinase activity 1/366 245/18639 0.00408163265306122 0.207862161257946 0.992487209352795 0.999953254923288 GO:0044025 histone H2BS14 kinase activity 1/366 245/18639 0.00408163265306122 0.207862161257946 0.992487209352795 0.999953254923288 GO:0072354 histone H3T3 kinase activity 1/366 245/18639 0.00408163265306122 0.207862161257946 0.992487209352795 0.999953254923288 GO:0072371 histone H2AS121 kinase activity 1/366 245/18639 0.00408163265306122 0.207862161257946 0.992487209352795 0.999953254923288 GO:0072518 Rho-dependent protein serine/threonine kinase activity 1/366 245/18639 0.00408163265306122 0.207862161257946 0.992487209352795 0.999953254923288 GO:0140823 histone H2BS36 kinase activity 1/366 245/18639 0.00408163265306122 0.207862161257946 0.992487209352795 0.999953254923288 GO:0140855 histone H3S57 kinase activity 1/366 245/18639 0.00408163265306122 0.207862161257946 0.992487209352795 0.999953254923288 GO:0140995 histone H2A kinase activity 1/366 245/18639 0.00408163265306122 0.207862161257946 0.992487209352795 0.999953254923288 GO:0140997 histone H4 kinase activity 1/366 245/18639 0.00408163265306122 0.207862161257946 0.992487209352795 0.999953254923288 GO:0140998 histone H2B kinase activity 1/366 245/18639 0.00408163265306122 0.207862161257946 0.992487209352795 0.999953254923288 GO:1990244 histone H2AT120 kinase activity 1/366 245/18639 0.00408163265306122 0.207862161257946 0.992487209352795 0.999953254923288 GO:0004677 DNA-dependent protein kinase activity 1/366 246/18639 0.0040650406504065 0.207017193122751 0.992636697304131 0.999953254923288 GO:0140857 histone H3T45 kinase activity 1/366 246/18639 0.0040650406504065 0.207017193122751 0.992636697304131 0.999953254923288 GO:0035402 histone H3T11 kinase activity 1/366 247/18639 0.00404858299595142 0.206179066834805 0.992783218740911 0.999953254923288 GO:0035403 histone H3T6 kinase activity 1/366 247/18639 0.00404858299595142 0.206179066834805 0.992783218740911 0.999953254923288 GO:0004679 AMP-activated protein kinase activity 1/366 248/18639 0.00403225806451613 0.205347699629825 0.992926832374057 0.999953254923288 GO:0140104 molecular carrier activity 1/366 249/18639 0.00401606425702811 0.204523010073079 0.993067595755662 0.999953254923288 GO:0106310 protein serine kinase activity 2/366 361/18639 0.00554016620498615 0.28213977566868 0.993931170233174 0.999953254923288 GO:0042578 phosphoric ester hydrolase activity 2/366 363/18639 0.00550964187327824 0.280585286546538 0.994142778194242 0.999953254923288 GO:0016791 phosphatase activity 1/366 273/18639 0.00366300366300366 0.18654296523149 0.995722222443864 0.999953254923288 GO:0140098 catalytic activity, acting on RNA 2/366 387/18639 0.00516795865633075 0.263184648621172 0.996182193471447 0.999953254923288 GO:0016887 ATP hydrolysis activity 2/366 417/18639 0.00479616306954436 0.244250501238354 0.997775434860698 0.999953254923288 GO:0022836 gated channel activity 1/366 318/18639 0.00314465408805031 0.160145375811939 0.998272778470554 0.999953254923288 GO:0140097 catalytic activity, acting on DNA 1/366 336/18639 0.00297619047619048 0.151566159250585 0.998799046228578 0.999953254923288 GO:0016755 aminoacyltransferase activity 1/366 496/18639 0.00201612903225806 0.102673849814913 0.999953254923288 0.999953254923288