ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0031994 insulin-like growth factor I binding 6/159 13/18639 0.461538461538462 54.1044992743106 5.72527520498009e-10 2.29011008199204e-07 GO:0005520 insulin-like growth factor binding 6/159 19/18639 0.315789473684211 37.0188679245283 8.67708764248875e-09 1.73541752849775e-06 GO:0050840 extracellular matrix binding 8/159 67/18639 0.119402985074627 13.9971838918614 1.00027425707576e-07 1.33369900943435e-05 GO:0005518 collagen binding 8/159 72/18639 0.111111111111111 13.0251572327044 1.77058478222446e-07 1.77058478222446e-05 GO:0005178 integrin binding 10/159 161/18639 0.062111801242236 7.28114379467948 1.2359428772607e-06 9.88754301808559e-05 GO:0005201 extracellular matrix structural constituent 10/159 168/18639 0.0595238095238095 6.9777628032345 1.81957473529847e-06 0.000121304982353232 GO:0019838 growth factor binding 9/159 136/18639 0.0661764705882353 7.75763041065483 2.53360579783498e-06 0.000144777474161999 GO:0008191 metalloendopeptidase inhibitor activity 4/159 14/18639 0.285714285714286 33.4932614555256 4.7752664570938e-06 0.00023876332285469 GO:0005539 glycosaminoglycan binding 11/159 242/18639 0.0454545454545455 5.32847341337907 7.52057500140123e-06 0.000334247777840055 GO:0033218 amide binding 11/159 247/18639 0.0445344129554656 5.22060957910014 9.12363317775466e-06 0.000364945327110186 GO:0008201 heparin binding 9/159 172/18639 0.0523255813953488 6.13394032470382 1.71186653342242e-05 0.000622496921244516 GO:0061134 peptidase regulator activity 10/159 226/18639 0.0442477876106195 5.18700951744866 2.48702846285079e-05 0.00082900948761693 GO:0030021 extracellular matrix structural constituent conferring compression resistance 4/159 22/18639 0.181818181818182 21.3138936535163 3.30869195916007e-05 0.00101805906435694 GO:0008009 chemokine activity 5/159 45/18639 0.111111111111111 13.0251572327044 3.93394760709014e-05 0.00112398503059718 GO:0023026 MHC class II protein complex binding 4/159 27/18639 0.148148148148148 17.3668763102725 7.67875908232117e-05 0.00204766908861898 GO:0003779 actin binding 13/159 443/18639 0.0293453724604966 3.44005281315218 0.000112548287075119 0.00276570897173379 GO:0001968 fibronectin binding 4/159 30/18639 0.133333333333333 15.6301886792453 0.000117542631298686 0.00276570897173379 GO:1901681 sulfur compound binding 10/159 275/18639 0.0363636363636364 4.26277873070326 0.000128604215121265 0.00285787144713923 GO:0061135 endopeptidase regulator activity 8/159 184/18639 0.0434782608695652 5.09680065627564 0.00018472779793312 0.00379727521956016 GO:0004175 endopeptidase activity 12/159 405/18639 0.0296296296296296 3.47337526205451 0.000189863760978008 0.00379727521956016 GO:0038024 cargo receptor activity 5/159 65/18639 0.0769230769230769 9.01741654571843 0.000231882354164348 0.00441680674598758 GO:0023023 MHC protein complex binding 4/159 37/18639 0.108108108108108 12.6731259561448 0.000270427752839836 0.00491686823345157 GO:0042277 peptide binding 9/159 249/18639 0.036144578313253 4.23709934075926 0.000293067549126355 0.00509682694132791 GO:0004222 metalloendopeptidase activity 6/159 110/18639 0.0545454545454545 6.39416809605489 0.000361668957822137 0.00599080660572899 GO:0042379 chemokine receptor binding 5/159 72/18639 0.0694444444444444 8.14072327044025 0.000374425412858062 0.00599080660572899 GO:0004866 endopeptidase inhibitor activity 7/159 161/18639 0.0434782608695652 5.09680065627564 0.000468513416616146 0.00720325664896633 GO:0008083 growth factor activity 7/159 162/18639 0.0432098765432099 5.06533892382949 0.000486219823805228 0.00720325664896633 GO:0033293 monocarboxylic acid binding 5/159 79/18639 0.0632911392405063 7.41939336040124 0.000574959870762297 0.00821371243946138 GO:0030414 peptidase inhibitor activity 7/159 169/18639 0.0414201183431953 4.85553198615608 0.000625646200516238 0.00862960276574122 GO:0005504 fatty acid binding 4/159 47/18639 0.0851063829787234 9.97671617824167 0.000683582460810237 0.00911443281080316 GO:0001540 amyloid-beta binding 5/159 83/18639 0.0602409638554217 7.06183223459877 0.00072075630865268 0.00930008140197006 GO:0004857 enzyme inhibitor activity 11/159 416/18639 0.0264423076923077 3.09973693759071 0.000904641212137374 0.0109472751823902 GO:0005125 cytokine activity 8/159 234/18639 0.0341880341880342 4.00774068698597 0.000914034324550611 0.0109472751823902 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 12/159 484/18639 0.0247933884297521 2.90644004366131 0.000930518390503167 0.0109472751823902 GO:0008237 metallopeptidase activity 7/159 184/18639 0.0380434782608696 4.45970057424118 0.00103118103086484 0.0116958010655191 GO:0001216 DNA-binding transcription activator activity 12/159 491/18639 0.0244399185336049 2.86500403489221 0.00105262209589672 0.0116958010655191 GO:0002020 protease binding 6/159 136/18639 0.0441176470588235 5.17175360710322 0.00110707944199335 0.011923284708818 GO:0031406 carboxylic acid binding 7/159 187/18639 0.0374331550802139 4.38815457572394 0.00113271204733771 0.011923284708818 GO:0043177 organic acid binding 7/159 189/18639 0.037037037037037 4.34171907756813 0.00120464759715426 0.0120962561573758 GO:0120020 cholesterol transfer activity 3/159 25/18639 0.12 14.0671698113208 0.0012205419180606 0.0120962561573758 GO:0140313 molecular sequestering activity 4/159 55/18639 0.0727272727272727 8.52555746140652 0.00123986625613102 0.0120962561573758 GO:0050750 low-density lipoprotein particle receptor binding 3/159 26/18639 0.115384615384615 13.5261248185776 0.00137115423303481 0.0130586117431887 GO:0031210 phosphatidylcholine binding 3/159 30/18639 0.1 11.722641509434 0.00208834474232187 0.0194264627192732 GO:0140375 immune receptor activity 6/159 156/18639 0.0384615384615385 4.50870827285922 0.00222666008700831 0.0202423644273483 GO:0070325 lipoprotein particle receptor binding 3/159 31/18639 0.0967741935483871 11.3444917833232 0.00229773197059109 0.0204242841830319 GO:0071813 lipoprotein particle binding 3/159 32/18639 0.09375 10.9899764150943 0.00251968323963506 0.0209973603302921 GO:0071814 protein-lipid complex binding 3/159 32/18639 0.09375 10.9899764150943 0.00251968323963506 0.0209973603302921 GO:0120015 sterol transfer activity 3/159 32/18639 0.09375 10.9899764150943 0.00251968323963506 0.0209973603302921 GO:0140311 protein sequestering activity 3/159 33/18639 0.0909090909090909 10.6569468267581 0.00275444637838958 0.0224852765582823 GO:0032395 MHC class II receptor activity 2/159 10/18639 0.2 23.4452830188679 0.00311116788826917 0.0248893431061533 GO:0008199 ferric iron binding 2/159 11/18639 0.181818181818182 21.3138936535163 0.00378129751912596 0.0294327828782836 GO:0043394 proteoglycan binding 3/159 37/18639 0.0810810810810811 9.50484446710862 0.00382626177417687 0.0294327828782836 GO:0046332 SMAD binding 4/159 79/18639 0.0506329113924051 5.93551468832099 0.00466513075173474 0.0352085339753565 GO:0050997 quaternary ammonium group binding 3/159 40/18639 0.075 8.79198113207547 0.00477548426893854 0.0353739575476929 GO:0008035 high-density lipoprotein particle binding 2/159 13/18639 0.153846153846154 18.0348330914369 0.0053028845429899 0.0385664330399266 GO:0042056 chemoattractant activity 3/159 42/18639 0.0714285714285714 8.3733153638814 0.00548040214812776 0.039145729629484 GO:0030547 signaling receptor inhibitor activity 3/159 44/18639 0.0681818181818182 7.99271012006861 0.00624459408571067 0.0438217128821801 GO:0042605 peptide antigen binding 3/159 45/18639 0.0666666666666667 7.81509433962264 0.00664930655245166 0.0458572865686322 GO:0004197 cysteine-type endopeptidase activity 4/159 88/18639 0.0454545454545455 5.32847341337907 0.00682628781256703 0.0462799173733358 GO:0005523 tropomyosin binding 2/159 15/18639 0.133333333333333 15.6301886792453 0.00705915794384551 0.0462895602875115 GO:0051371 muscle alpha-actinin binding 2/159 15/18639 0.133333333333333 15.6301886792453 0.00705915794384551 0.0462895602875115 GO:0019955 cytokine binding 5/159 144/18639 0.0347222222222222 4.07036163522013 0.00789459853282496 0.050932893760161 GO:0042562 hormone binding 4/159 94/18639 0.0425531914893617 4.98835808912084 0.00858406133707538 0.0545019767433357 GO:0048020 CCR chemokine receptor binding 3/159 50/18639 0.06 7.03358490566038 0.0089045378098099 0.0556533613113119 GO:0051015 actin filament binding 6/159 209/18639 0.0287081339712919 3.36535162950257 0.00915248367460853 0.0563229764591294 GO:0005126 cytokine receptor binding 7/159 275/18639 0.0254545454545455 2.98394511149228 0.00942008402228189 0.05709141831686 GO:0008525 phosphatidylcholine transporter activity 2/159 18/18639 0.111111111111111 13.0251572327044 0.0101154808810929 0.0603909306333907 GO:0017046 peptide hormone binding 3/159 53/18639 0.0566037735849057 6.63545745817017 0.0104472919913259 0.0614546587725052 GO:0046624 sphingolipid transporter activity 2/159 19/18639 0.105263157894737 12.3396226415094 0.0112427281941299 0.0639695153663501 GO:0097001 ceramide binding 2/159 19/18639 0.105263157894737 12.3396226415094 0.0112427281941299 0.0639695153663501 GO:0008238 exopeptidase activity 4/159 102/18639 0.0392156862745098 4.59711431742508 0.0113545889775271 0.0639695153663501 GO:0016504 peptidase activator activity 3/159 57/18639 0.0526315789473684 6.16981132075472 0.0127310077632573 0.0707278209069851 GO:0019888 protein phosphatase regulator activity 4/159 107/18639 0.0373831775700935 4.38229589137718 0.0133476461750027 0.0731377872602886 GO:0072542 protein phosphatase activator activity 2/159 21/18639 0.0952380952380952 11.1644204851752 0.0136540315066667 0.0734466253584564 GO:0005496 steroid binding 4/159 108/18639 0.037037037037037 4.34171907756813 0.0137712422547106 0.0734466253584564 GO:0004252 serine-type endopeptidase activity 5/159 176/18639 0.0284090909090909 3.33029588336192 0.0175907322178047 0.0916061067816751 GO:0050431 transforming growth factor beta binding 2/159 24/18639 0.0833333333333333 9.7688679245283 0.0176486809018538 0.0916061067816751 GO:0019208 phosphatase regulator activity 4/159 117/18639 0.0341880341880342 4.00774068698597 0.0179703487753613 0.0916061067816751 GO:0120013 lipid transfer activity 3/159 65/18639 0.0461538461538462 5.41044992743106 0.0180922060893808 0.0916061067816751 GO:0019211 phosphatase activator activity 2/159 25/18639 0.08 9.37811320754717 0.0190772147265315 0.0953860736326575 GO:0032934 sterol binding 3/159 68/18639 0.0441176470588235 5.17175360710322 0.0203791900103948 0.0978700941316963 GO:0008198 ferrous iron binding 2/159 26/18639 0.0769230769230769 9.01741654571843 0.0205527197676562 0.0978700941316963 GO:0019865 immunoglobulin binding 2/159 26/18639 0.0769230769230769 9.01741654571843 0.0205527197676562 0.0978700941316963 GO:0070412 R-SMAD binding 2/159 26/18639 0.0769230769230769 9.01741654571843 0.0205527197676562 0.0978700941316963 GO:0097110 scaffold protein binding 3/159 70/18639 0.0428571428571429 5.02398921832884 0.0219881577657524 0.103473683603541 GO:0046625 sphingolipid binding 2/159 28/18639 0.0714285714285714 8.3733153638814 0.0236410764514001 0.108694604374253 GO:0051393 alpha-actinin binding 2/159 28/18639 0.0714285714285714 8.3733153638814 0.0236410764514001 0.108694604374253 GO:0003785 actin monomer binding 2/159 29/18639 0.0689655172413793 8.08458035133377 0.0252521736306728 0.113404348797876 GO:0051861 glycolipid binding 2/159 29/18639 0.0689655172413793 8.08458035133377 0.0252521736306728 0.113404348797876 GO:0008236 serine-type peptidase activity 5/159 194/18639 0.0257731958762887 3.02129935810154 0.025515978479522 0.113404348797876 GO:0017171 serine hydrolase activity 5/159 198/18639 0.0252525252525253 2.96026300743282 0.0275427819791718 0.121067173534821 GO:0071889 14-3-3 protein binding 2/159 33/18639 0.0606060606060606 7.10463121783877 0.0321227506789227 0.13966413338662 GO:0004869 cysteine-type endopeptidase inhibitor activity 2/159 36/18639 0.0555555555555556 6.5125786163522 0.0377000340366574 0.162150684028634 GO:0042805 actinin binding 2/159 37/18639 0.0540540540540541 6.33656297807241 0.0396356781659419 0.168662460280604 GO:0043178 alcohol binding 3/159 92/18639 0.0326086956521739 3.82260049220673 0.0441086059226942 0.185720445990291 GO:0004177 aminopeptidase activity 2/159 40/18639 0.05 5.86132075471698 0.0456614329302123 0.190255970542551 GO:0004867 serine-type endopeptidase inhibitor activity 3/159 95/18639 0.0315789473684211 3.70188679245283 0.0477400897629419 0.194858976382536 GO:0042287 MHC protein binding 2/159 41/18639 0.0487804878048781 5.71836171191901 0.0477404492137213 0.194858976382536 GO:0004896 cytokine receptor activity 3/159 96/18639 0.03125 3.66332547169811 0.0489823559793996 0.197908509007675 GO:0048156 tau protein binding 2/159 43/18639 0.0465116279069767 5.45239139973673 0.0519997170446063 0.207998868178425 GO:0004180 carboxypeptidase activity 2/159 46/18639 0.0434782608695652 5.09680065627564 0.0586310079385442 0.232202011637799 GO:0008013 beta-catenin binding 3/159 106/18639 0.0283018867924528 3.31772872908508 0.0622578178207803 0.244148305179531 GO:0005543 phospholipid binding 8/159 497/18639 0.0160965794768612 1.88694430735356 0.0632537983806463 0.245645818953966 GO:0005319 lipid transporter activity 4/159 178/18639 0.0224719101123595 2.63430146279415 0.0662545691984403 0.254825266147848 GO:0004864 protein phosphatase inhibitor activity 2/159 53/18639 0.0377358490566038 4.42363830544678 0.0751396057108282 0.275756473244303 GO:0001221 transcription coregulator binding 3/159 115/18639 0.0260869565217391 3.05808039376538 0.075478820815904 0.275756473244303 GO:0008234 cysteine-type peptidase activity 4/159 187/18639 0.0213903743315508 2.50751690041368 0.0763508194544705 0.275756473244303 GO:0015485 cholesterol binding 2/159 54/18639 0.037037037037037 4.34171907756813 0.0776067535423984 0.275756473244303 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 6/159 349/18639 0.0171919770773639 2.01535384116343 0.0788698160649264 0.275756473244303 GO:0003680 minor groove of adenine-thymine-rich DNA binding 1/159 10/18639 0.1 11.722641509434 0.0821228444277067 0.275756473244303 GO:0003796 lysozyme activity 1/159 10/18639 0.1 11.722641509434 0.0821228444277067 0.275756473244303 GO:0005381 iron ion transmembrane transporter activity 1/159 10/18639 0.1 11.722641509434 0.0821228444277067 0.275756473244303 GO:0015187 glycine transmembrane transporter activity 1/159 10/18639 0.1 11.722641509434 0.0821228444277067 0.275756473244303 GO:0015658 branched-chain amino acid transmembrane transporter activity 1/159 10/18639 0.1 11.722641509434 0.0821228444277067 0.275756473244303 GO:0035374 chondroitin sulfate binding 1/159 10/18639 0.1 11.722641509434 0.0821228444277067 0.275756473244303 GO:0043208 glycosphingolipid binding 1/159 10/18639 0.1 11.722641509434 0.0821228444277067 0.275756473244303 GO:0050815 phosphoserine residue binding 1/159 10/18639 0.1 11.722641509434 0.0821228444277067 0.275756473244303 GO:0019212 phosphatase inhibitor activity 2/159 56/18639 0.0357142857142857 4.1866576819407 0.0826163894688148 0.275756473244303 GO:0001851 complement component C3b binding 1/159 11/18639 0.0909090909090909 10.6569468267581 0.0899569991185648 0.275756473244303 GO:0003953 NAD+ nucleosidase activity 1/159 11/18639 0.0909090909090909 10.6569468267581 0.0899569991185648 0.275756473244303 GO:0008432 JUN kinase binding 1/159 11/18639 0.0909090909090909 10.6569468267581 0.0899569991185648 0.275756473244303 GO:0008526 phosphatidylinositol transfer activity 1/159 11/18639 0.0909090909090909 10.6569468267581 0.0899569991185648 0.275756473244303 GO:0010854 adenylate cyclase regulator activity 1/159 11/18639 0.0909090909090909 10.6569468267581 0.0899569991185648 0.275756473244303 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water 1/159 11/18639 0.0909090909090909 10.6569468267581 0.0899569991185648 0.275756473244303 GO:0019864 IgG binding 1/159 11/18639 0.0909090909090909 10.6569468267581 0.0899569991185648 0.275756473244303 GO:0034713 type I transforming growth factor beta receptor binding 1/159 11/18639 0.0909090909090909 10.6569468267581 0.0899569991185648 0.275756473244303 GO:0042608 T cell receptor binding 1/159 11/18639 0.0909090909090909 10.6569468267581 0.0899569991185648 0.275756473244303 GO:0050786 RAGE receptor binding 1/159 11/18639 0.0909090909090909 10.6569468267581 0.0899569991185648 0.275756473244303 GO:0050998 nitric-oxide synthase binding 1/159 11/18639 0.0909090909090909 10.6569468267581 0.0899569991185648 0.275756473244303 GO:0097493 structural molecule activity conferring elasticity 1/159 11/18639 0.0909090909090909 10.6569468267581 0.0899569991185648 0.275756473244303 GO:0004879 nuclear receptor activity 2/159 59/18639 0.0338983050847458 3.97377678285897 0.0903102449875092 0.275756473244303 GO:0030246 carbohydrate binding 5/159 280/18639 0.0178571428571429 2.09332884097035 0.0920511589249329 0.27894290583313 GO:0098531 ligand-modulated transcription factor activity 2/159 60/18639 0.0333333333333333 3.90754716981132 0.0929203751012066 0.279459774740471 GO:0004859 phospholipase inhibitor activity 1/159 12/18639 0.0833333333333333 9.7688679245283 0.097724705643159 0.283260016356983 GO:0017166 vinculin binding 1/159 12/18639 0.0833333333333333 9.7688679245283 0.097724705643159 0.283260016356983 GO:0035014 phosphatidylinositol 3-kinase regulator activity 1/159 12/18639 0.0833333333333333 9.7688679245283 0.097724705643159 0.283260016356983 GO:0035259 nuclear glucocorticoid receptor binding 1/159 12/18639 0.0833333333333333 9.7688679245283 0.097724705643159 0.283260016356983 GO:0035497 cAMP response element binding 1/159 12/18639 0.0833333333333333 9.7688679245283 0.097724705643159 0.283260016356983 GO:0005542 folic acid binding 1/159 13/18639 0.0769230769230769 9.01741654571843 0.105426524068173 0.294899368022862 GO:0019855 calcium channel inhibitor activity 1/159 13/18639 0.0769230769230769 9.01741654571843 0.105426524068173 0.294899368022862 GO:0035325 Toll-like receptor binding 1/159 13/18639 0.0769230769230769 9.01741654571843 0.105426524068173 0.294899368022862 GO:0039706 co-receptor binding 1/159 13/18639 0.0769230769230769 9.01741654571843 0.105426524068173 0.294899368022862 GO:0045028 G protein-coupled purinergic nucleotide receptor activity 1/159 13/18639 0.0769230769230769 9.01741654571843 0.105426524068173 0.294899368022862 GO:0008235 metalloexopeptidase activity 2/159 66/18639 0.0303030303030303 3.55231560891938 0.109019948975019 0.297991109332823 GO:0001664 G protein-coupled receptor binding 5/159 297/18639 0.0168350168350168 1.97350867162188 0.110874629325451 0.297991109332823 GO:0005161 platelet-derived growth factor receptor binding 1/159 14/18639 0.0714285714285714 8.3733153638814 0.113063009769513 0.297991109332823 GO:0019992 diacylglycerol binding 1/159 14/18639 0.0714285714285714 8.3733153638814 0.113063009769513 0.297991109332823 GO:0031404 chloride ion binding 1/159 14/18639 0.0714285714285714 8.3733153638814 0.113063009769513 0.297991109332823 GO:0042043 neurexin family protein binding 1/159 14/18639 0.0714285714285714 8.3733153638814 0.113063009769513 0.297991109332823 GO:0043176 amine binding 1/159 14/18639 0.0714285714285714 8.3733153638814 0.113063009769513 0.297991109332823 GO:0061783 peptidoglycan muralytic activity 1/159 14/18639 0.0714285714285714 8.3733153638814 0.113063009769513 0.297991109332823 GO:0005548 phospholipid transporter activity 2/159 68/18639 0.0294117647058824 3.44783573806881 0.114540790494242 0.297991109332823 GO:1990841 promoter-specific chromatin binding 2/159 68/18639 0.0294117647058824 3.44783573806881 0.114540790494242 0.297991109332823 GO:0070851 growth factor receptor binding 3/159 139/18639 0.0215827338129496 2.53006651282747 0.116019639722296 0.297991109332823 GO:0005041 low-density lipoprotein particle receptor activity 1/159 15/18639 0.0666666666666667 7.81509433962264 0.120634713471347 0.297991109332823 GO:0031005 filamin binding 1/159 15/18639 0.0666666666666667 7.81509433962264 0.120634713471347 0.297991109332823 GO:0120283 protein serine/threonine kinase binding 1/159 15/18639 0.0666666666666667 7.81509433962264 0.120634713471347 0.297991109332823 GO:0140297 DNA-binding transcription factor binding 7/159 488/18639 0.014344262295082 1.68152644602536 0.124673915462037 0.297991109332823 GO:0019903 protein phosphatase binding 3/159 144/18639 0.0208333333333333 2.44221698113208 0.125323538544113 0.297991109332823 GO:0005024 transforming growth factor beta receptor activity 1/159 16/18639 0.0625 7.32665094339623 0.128142181284817 0.297991109332823 GO:0005149 interleukin-1 receptor binding 1/159 16/18639 0.0625 7.32665094339623 0.128142181284817 0.297991109332823 GO:0005521 lamin binding 1/159 16/18639 0.0625 7.32665094339623 0.128142181284817 0.297991109332823 GO:0008142 oxysterol binding 1/159 16/18639 0.0625 7.32665094339623 0.128142181284817 0.297991109332823 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 1/159 16/18639 0.0625 7.32665094339623 0.128142181284817 0.297991109332823 GO:0016722 oxidoreductase activity, acting on metal ions 1/159 16/18639 0.0625 7.32665094339623 0.128142181284817 0.297991109332823 GO:0019841 retinol binding 1/159 16/18639 0.0625 7.32665094339623 0.128142181284817 0.297991109332823 GO:0022858 alanine transmembrane transporter activity 1/159 16/18639 0.0625 7.32665094339623 0.128142181284817 0.297991109332823 GO:0055102 lipase inhibitor activity 1/159 16/18639 0.0625 7.32665094339623 0.128142181284817 0.297991109332823 GO:0061809 NAD+ nucleosidase activity, cyclic ADP-ribose generating 1/159 16/18639 0.0625 7.32665094339623 0.128142181284817 0.297991109332823 GO:0140328 floppase activity 1/159 16/18639 0.0625 7.32665094339623 0.128142181284817 0.297991109332823 GO:0043539 protein serine/threonine kinase activator activity 2/159 73/18639 0.0273972602739726 3.21168260532437 0.128641853270362 0.297991109332823 GO:0019003 GDP binding 2/159 75/18639 0.0266666666666667 3.12603773584906 0.134391732782841 0.297991109332823 GO:0044183 protein folding chaperone 2/159 75/18639 0.0266666666666667 3.12603773584906 0.134391732782841 0.297991109332823 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 1/159 17/18639 0.0588235294117647 6.89567147613763 0.135585954746435 0.297991109332823 GO:0008429 phosphatidylethanolamine binding 1/159 17/18639 0.0588235294117647 6.89567147613763 0.135585954746435 0.297991109332823 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 1/159 17/18639 0.0588235294117647 6.89567147613763 0.135585954746435 0.297991109332823 GO:0030169 low-density lipoprotein particle binding 1/159 17/18639 0.0588235294117647 6.89567147613763 0.135585954746435 0.297991109332823 GO:0036041 long-chain fatty acid binding 1/159 17/18639 0.0588235294117647 6.89567147613763 0.135585954746435 0.297991109332823 GO:0038191 neuropilin binding 1/159 17/18639 0.0588235294117647 6.89567147613763 0.135585954746435 0.297991109332823 GO:0046965 nuclear retinoid X receptor binding 1/159 17/18639 0.0588235294117647 6.89567147613763 0.135585954746435 0.297991109332823 GO:0048038 quinone binding 1/159 17/18639 0.0588235294117647 6.89567147613763 0.135585954746435 0.297991109332823 GO:0070492 oligosaccharide binding 1/159 17/18639 0.0588235294117647 6.89567147613763 0.135585954746435 0.297991109332823 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 1/159 18/18639 0.0555555555555556 6.5125786163522 0.14296657085616 0.301310061937563 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 1/159 18/18639 0.0555555555555556 6.5125786163522 0.14296657085616 0.301310061937563 GO:0030228 lipoprotein particle receptor activity 1/159 18/18639 0.0555555555555556 6.5125786163522 0.14296657085616 0.301310061937563 GO:0032393 MHC class I receptor activity 1/159 18/18639 0.0555555555555556 6.5125786163522 0.14296657085616 0.301310061937563 GO:0034185 apolipoprotein binding 1/159 18/18639 0.0555555555555556 6.5125786163522 0.14296657085616 0.301310061937563 GO:0035615 clathrin adaptor activity 1/159 18/18639 0.0555555555555556 6.5125786163522 0.14296657085616 0.301310061937563 GO:1901611 phosphatidylglycerol binding 1/159 18/18639 0.0555555555555556 6.5125786163522 0.14296657085616 0.301310061937563 GO:0019199 transmembrane receptor protein kinase activity 2/159 78/18639 0.0256410256410256 3.00580551523948 0.143122279420342 0.301310061937563 GO:0016918 retinal binding 1/159 19/18639 0.0526315789473684 6.16981132075472 0.150284562115162 0.313092837739921 GO:0043395 heparan sulfate proteoglycan binding 1/159 19/18639 0.0526315789473684 6.16981132075472 0.150284562115162 0.313092837739921 GO:0001614 purinergic nucleotide receptor activity 1/159 20/18639 0.05 5.86132075471698 0.157540456563265 0.315199963894158 GO:0010851 cyclase regulator activity 1/159 20/18639 0.05 5.86132075471698 0.157540456563265 0.315199963894158 GO:0016004 phospholipase activator activity 1/159 20/18639 0.05 5.86132075471698 0.157540456563265 0.315199963894158 GO:0016502 nucleotide receptor activity 1/159 20/18639 0.05 5.86132075471698 0.157540456563265 0.315199963894158 GO:0016505 peptidase activator activity involved in apoptotic process 1/159 20/18639 0.05 5.86132075471698 0.157540456563265 0.315199963894158 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 1/159 20/18639 0.05 5.86132075471698 0.157540456563265 0.315199963894158 GO:0042288 MHC class I protein binding 1/159 20/18639 0.05 5.86132075471698 0.157540456563265 0.315199963894158 GO:0045296 cadherin binding 5/159 334/18639 0.0149700598802395 1.75488645350808 0.157599981947079 0.315199963894158 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 1/159 21/18639 0.0476190476190476 5.5822102425876 0.164734777816095 0.323009368266854 GO:0001846 opsonin binding 1/159 21/18639 0.0476190476190476 5.5822102425876 0.164734777816095 0.323009368266854 GO:0036122 BMP binding 1/159 21/18639 0.0476190476190476 5.5822102425876 0.164734777816095 0.323009368266854 GO:0140312 cargo adaptor activity 1/159 21/18639 0.0476190476190476 5.5822102425876 0.164734777816095 0.323009368266854 GO:0016209 antioxidant activity 2/159 86/18639 0.0232558139534884 2.72619569986836 0.16694155330175 0.325739616198536 GO:0061133 endopeptidase activator activity 1/159 22/18639 0.0454545454545455 5.32847341337907 0.171868045101907 0.333724359421179 GO:0004602 glutathione peroxidase activity 1/159 23/18639 0.0434782608695652 5.09680065627564 0.178940773298115 0.342470379517923 GO:0005158 insulin receptor binding 1/159 23/18639 0.0434782608695652 5.09680065627564 0.178940773298115 0.342470379517923 GO:0005212 structural constituent of eye lens 1/159 23/18639 0.0434782608695652 5.09680065627564 0.178940773298115 0.342470379517923 GO:0072341 modified amino acid binding 2/159 91/18639 0.021978021978022 2.57640472734812 0.182155713564747 0.342950806619597 GO:0005540 hyaluronic acid binding 1/159 24/18639 0.0416666666666667 4.88443396226415 0.185953472967518 0.342950806619597 GO:0030215 semaphorin receptor binding 1/159 24/18639 0.0416666666666667 4.88443396226415 0.185953472967518 0.342950806619597 GO:0035035 histone acetyltransferase binding 1/159 24/18639 0.0416666666666667 4.88443396226415 0.185953472967518 0.342950806619597 GO:0050699 WW domain binding 1/159 24/18639 0.0416666666666667 4.88443396226415 0.185953472967518 0.342950806619597 GO:0060229 lipase activator activity 1/159 24/18639 0.0416666666666667 4.88443396226415 0.185953472967518 0.342950806619597 GO:0070300 phosphatidic acid binding 1/159 24/18639 0.0416666666666667 4.88443396226415 0.185953472967518 0.342950806619597 GO:0003823 antigen binding 3/159 174/18639 0.0172413793103448 2.02114508783344 0.186050812591131 0.342950806619597 GO:0016410 N-acyltransferase activity 2/159 94/18639 0.0212765957446809 2.49417904456042 0.191380879489602 0.349152308405838 GO:0001848 complement binding 1/159 25/18639 0.04 4.68905660377359 0.192906650394225 0.349152308405838 GO:0008139 nuclear localization sequence binding 1/159 25/18639 0.04 4.68905660377359 0.192906650394225 0.349152308405838 GO:0042974 nuclear retinoic acid receptor binding 1/159 25/18639 0.04 4.68905660377359 0.192906650394225 0.349152308405838 GO:0005160 transforming growth factor beta receptor binding 1/159 26/18639 0.0384615384615385 4.50870827285922 0.199800807619288 0.35362974799874 GO:0030247 polysaccharide binding 1/159 26/18639 0.0384615384615385 4.50870827285922 0.199800807619288 0.35362974799874 GO:0043548 phosphatidylinositol 3-kinase binding 1/159 26/18639 0.0384615384615385 4.50870827285922 0.199800807619288 0.35362974799874 GO:0070006 metalloaminopeptidase activity 1/159 26/18639 0.0384615384615385 4.50870827285922 0.199800807619288 0.35362974799874 GO:0120014 phospholipid transfer activity 1/159 26/18639 0.0384615384615385 4.50870827285922 0.199800807619288 0.35362974799874 GO:0004364 glutathione transferase activity 1/159 27/18639 0.037037037037037 4.34171907756813 0.20663644247603 0.359367726045269 GO:0005104 fibroblast growth factor receptor binding 1/159 27/18639 0.037037037037037 4.34171907756813 0.20663644247603 0.359367726045269 GO:0008320 protein transmembrane transporter activity 1/159 27/18639 0.037037037037037 4.34171907756813 0.20663644247603 0.359367726045269 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 1/159 27/18639 0.037037037037037 4.34171907756813 0.20663644247603 0.359367726045269 GO:0046982 protein heterodimerization activity 5/159 369/18639 0.013550135501355 1.58843380886639 0.207972278965137 0.360125158381189 GO:0045499 chemorepellent activity 1/159 28/18639 0.0357142857142857 4.1866576819407 0.21341404862509 0.366376049141785 GO:0141052 histone H3 demethylase activity 1/159 28/18639 0.0357142857142857 4.1866576819407 0.21341404862509 0.366376049141785 GO:0004181 metallocarboxypeptidase activity 1/159 29/18639 0.0344827586206897 4.04229017566688 0.220134115589176 0.3746963669603 GO:0043236 laminin binding 1/159 29/18639 0.0344827586206897 4.04229017566688 0.220134115589176 0.3746963669603 GO:0019902 phosphatase binding 3/159 190/18639 0.0157894736842105 1.85094339622642 0.221083004414504 0.374716956634753 GO:0001965 G-protein alpha-subunit binding 1/159 30/18639 0.0333333333333333 3.90754716981132 0.226797128787528 0.379576784581636 GO:0032452 histone demethylase activity 1/159 30/18639 0.0333333333333333 3.90754716981132 0.226797128787528 0.379576784581636 GO:0048019 receptor antagonist activity 1/159 30/18639 0.0333333333333333 3.90754716981132 0.226797128787528 0.379576784581636 GO:0000149 SNARE binding 2/159 106/18639 0.0188679245283019 2.21181915272339 0.228803422508041 0.381339037513402 GO:0019207 kinase regulator activity 4/159 287/18639 0.0139372822299652 1.63381763197686 0.229989409262223 0.3817251606012 GO:0140457 protein demethylase activity 1/159 31/18639 0.032258064516129 3.78149726110773 0.233403569570094 0.3857910240828 GO:0022884 macromolecule transmembrane transporter activity 1/159 32/18639 0.03125 3.66332547169811 0.239953915251433 0.391761494288055 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/159 32/18639 0.03125 3.66332547169811 0.239953915251433 0.391761494288055 GO:0051059 NF-kappaB binding 1/159 32/18639 0.03125 3.66332547169811 0.239953915251433 0.391761494288055 GO:0140416 transcription regulator inhibitor activity 1/159 33/18639 0.0303030303030303 3.55231560891938 0.246448639144324 0.400729494543616 GO:0005200 structural constituent of cytoskeleton 2/159 112/18639 0.0178571428571429 2.09332884097035 0.247712168788181 0.401153309778431 GO:0016229 steroid dehydrogenase activity 1/159 35/18639 0.0285714285714286 3.34932614555256 0.259273095006743 0.417037810983965 GO:0005516 calmodulin binding 3/159 207/18639 0.0144927536231884 1.69893355209188 0.259606037337518 0.417037810983965 GO:0051082 unfolded protein binding 2/159 121/18639 0.0165289256198347 1.93762669577421 0.276157240949886 0.441435272670398 GO:0005501 retinoid binding 1/159 38/18639 0.0263157894736842 3.08490566037736 0.278104221782351 0.441435272670398 GO:0019840 isoprenoid binding 1/159 38/18639 0.0263157894736842 3.08490566037736 0.278104221782351 0.441435272670398 GO:0000217 DNA secondary structure binding 1/159 39/18639 0.0256410256410256 3.00580551523948 0.28427493457933 0.447677062329653 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 1/159 39/18639 0.0256410256410256 3.00580551523948 0.28427493457933 0.447677062329653 GO:0032451 demethylase activity 1/159 40/18639 0.025 2.93066037735849 0.290393229493409 0.453739421083452 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 1/159 40/18639 0.025 2.93066037735849 0.290393229493409 0.453739421083452 GO:0001530 lipopolysaccharide binding 1/159 41/18639 0.024390243902439 2.8591808559595 0.296459549000401 0.456091613846771 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 1/159 41/18639 0.024390243902439 2.8591808559595 0.296459549000401 0.456091613846771 GO:0015175 neutral L-amino acid transmembrane transporter activity 1/159 41/18639 0.024390243902439 2.8591808559595 0.296459549000401 0.456091613846771 GO:0140318 protein transporter activity 1/159 41/18639 0.024390243902439 2.8591808559595 0.296459549000401 0.456091613846771 GO:0035591 signaling adaptor activity 2/159 129/18639 0.0155038759689922 1.81746379991224 0.301401921605672 0.460037006638222 GO:0008307 structural constituent of muscle 1/159 42/18639 0.0238095238095238 2.7911051212938 0.302474331864631 0.460037006638222 GO:0048487 beta-tubulin binding 1/159 42/18639 0.0238095238095238 2.7911051212938 0.302474331864631 0.460037006638222 GO:0016798 hydrolase activity, acting on glycosyl bonds 2/159 130/18639 0.0153846153846154 1.80348330914369 0.304549152218471 0.461438109421925 GO:0008200 ion channel inhibitor activity 1/159 43/18639 0.0232558139534884 2.72619569986836 0.308438013169869 0.465566812331878 GO:0001046 core promoter sequence-specific DNA binding 1/159 44/18639 0.0227272727272727 2.66423670668954 0.314351024350015 0.467436467434967 GO:0001223 transcription coactivator binding 1/159 44/18639 0.0227272727272727 2.66423670668954 0.314351024350015 0.467436467434967 GO:0016248 channel inhibitor activity 1/159 44/18639 0.0227272727272727 2.66423670668954 0.314351024350015 0.467436467434967 GO:0030020 extracellular matrix structural constituent conferring tensile strength 1/159 44/18639 0.0227272727272727 2.66423670668954 0.314351024350015 0.467436467434967 GO:0046915 transition metal ion transmembrane transporter activity 1/159 45/18639 0.0222222222222222 2.60503144654088 0.320213793219515 0.470902637087522 GO:0140303 intramembrane lipid transporter activity 1/159 45/18639 0.0222222222222222 2.60503144654088 0.320213793219515 0.470902637087522 GO:0141110 transporter inhibitor activity 1/159 45/18639 0.0222222222222222 2.60503144654088 0.320213793219515 0.470902637087522 GO:0140359 ABC-type transporter activity 1/159 47/18639 0.0212765957446809 2.49417904456042 0.331790297367891 0.478286936420702 GO:0030295 protein kinase activator activity 2/159 139/18639 0.0143884892086331 1.68671100855165 0.33273990580163 0.478286936420702 GO:0038187 pattern recognition receptor activity 1/159 48/18639 0.0208333333333333 2.44221698113208 0.337504870448705 0.478286936420702 GO:0140693 molecular condensate scaffold activity 1/159 48/18639 0.0208333333333333 2.44221698113208 0.337504870448705 0.478286936420702 GO:0001222 transcription corepressor binding 1/159 49/18639 0.0204081632653061 2.39237581825183 0.343170876881854 0.478286936420702 GO:0005004 GPI-linked ephrin receptor activity 1/159 49/18639 0.0204081632653061 2.39237581825183 0.343170876881854 0.478286936420702 GO:0005008 hepatocyte growth factor receptor activity 1/159 49/18639 0.0204081632653061 2.39237581825183 0.343170876881854 0.478286936420702 GO:0005009 insulin receptor activity 1/159 49/18639 0.0204081632653061 2.39237581825183 0.343170876881854 0.478286936420702 GO:0005011 macrophage colony-stimulating factor receptor activity 1/159 49/18639 0.0204081632653061 2.39237581825183 0.343170876881854 0.478286936420702 GO:0005018 platelet-derived growth factor alpha-receptor activity 1/159 49/18639 0.0204081632653061 2.39237581825183 0.343170876881854 0.478286936420702 GO:0005020 stem cell factor receptor activity 1/159 49/18639 0.0204081632653061 2.39237581825183 0.343170876881854 0.478286936420702 GO:0008288 boss receptor activity 1/159 49/18639 0.0204081632653061 2.39237581825183 0.343170876881854 0.478286936420702 GO:0036332 placental growth factor receptor activity 1/159 49/18639 0.0204081632653061 2.39237581825183 0.343170876881854 0.478286936420702 GO:0038062 protein tyrosine kinase collagen receptor activity 1/159 49/18639 0.0204081632653061 2.39237581825183 0.343170876881854 0.478286936420702 GO:0060175 brain-derived neurotrophic factor receptor activity 1/159 49/18639 0.0204081632653061 2.39237581825183 0.343170876881854 0.478286936420702 GO:0005006 epidermal growth factor receptor activity 1/159 50/18639 0.02 2.34452830188679 0.348788726832138 0.479434676057921 GO:0005007 fibroblast growth factor receptor activity 1/159 50/18639 0.02 2.34452830188679 0.348788726832138 0.479434676057921 GO:0005017 platelet-derived growth factor receptor activity 1/159 50/18639 0.02 2.34452830188679 0.348788726832138 0.479434676057921 GO:0005019 platelet-derived growth factor beta-receptor activity 1/159 50/18639 0.02 2.34452830188679 0.348788726832138 0.479434676057921 GO:0005010 insulin-like growth factor receptor activity 1/159 51/18639 0.0196078431372549 2.29855715871254 0.354358827022234 0.480486545114893 GO:0005021 vascular endothelial growth factor receptor activity 1/159 51/18639 0.0196078431372549 2.29855715871254 0.354358827022234 0.480486545114893 GO:0005030 neurotrophin receptor activity 1/159 51/18639 0.0196078431372549 2.29855715871254 0.354358827022234 0.480486545114893 GO:0005048 signal sequence binding 1/159 51/18639 0.0196078431372549 2.29855715871254 0.354358827022234 0.480486545114893 GO:0030159 signaling receptor complex adaptor activity 1/159 52/18639 0.0192307692307692 2.25435413642961 0.359881580761391 0.483917070164109 GO:0019209 kinase activator activity 2/159 148/18639 0.0135135135135135 1.5841407445181 0.360603508629862 0.483917070164109 GO:0005003 ephrin receptor activity 1/159 53/18639 0.0188679245283019 2.21181915272339 0.365357387973902 0.483917070164109 GO:0005005 transmembrane-ephrin receptor activity 1/159 53/18639 0.0188679245283019 2.21181915272339 0.365357387973902 0.483917070164109 GO:0005246 calcium channel regulator activity 1/159 53/18639 0.0188679245283019 2.21181915272339 0.365357387973902 0.483917070164109 GO:0038064 collagen receptor activity 1/159 53/18639 0.0188679245283019 2.21181915272339 0.365357387973902 0.483917070164109 GO:0140296 general transcription initiation factor binding 1/159 53/18639 0.0188679245283019 2.21181915272339 0.365357387973902 0.483917070164109 GO:0019842 vitamin binding 2/159 150/18639 0.0133333333333333 1.56301886792453 0.36673993378695 0.484145127111485 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 1/159 54/18639 0.0185185185185185 2.17085953878407 0.370786645227327 0.48468842513376 GO:0050661 NADP binding 1/159 54/18639 0.0185185185185185 2.17085953878407 0.370786645227327 0.48468842513376 GO:0140463 chromatin-protein adaptor activity 1/159 54/18639 0.0185185185185185 2.17085953878407 0.370786645227327 0.48468842513376 GO:0098632 cell-cell adhesion mediator activity 1/159 55/18639 0.0181818181818182 2.13138936535163 0.376169745760491 0.490123447244939 GO:0005506 iron ion binding 2/159 154/18639 0.012987012987013 1.52242097525116 0.378944208139992 0.492135335246743 GO:0004601 peroxidase activity 1/159 57/18639 0.0175438596491228 2.05660377358491 0.386799033144016 0.500710722516525 GO:0001786 phosphatidylserine binding 1/159 59/18639 0.0169491525423729 1.98688839142949 0.397248330509653 0.506048828674717 GO:0015459 potassium channel regulator activity 1/159 59/18639 0.0169491525423729 1.98688839142949 0.397248330509653 0.506048828674717 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 1/159 59/18639 0.0169491525423729 1.98688839142949 0.397248330509653 0.506048828674717 GO:0045309 protein phosphorylated amino acid binding 1/159 59/18639 0.0169491525423729 1.98688839142949 0.397248330509653 0.506048828674717 GO:0070888 E-box binding 1/159 59/18639 0.0169491525423729 1.98688839142949 0.397248330509653 0.506048828674717 GO:0004714 transmembrane receptor protein tyrosine kinase activity 1/159 60/18639 0.0166666666666667 1.95377358490566 0.402406431448779 0.509375229681999 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 1/159 60/18639 0.0166666666666667 1.95377358490566 0.402406431448779 0.509375229681999 GO:0015026 coreceptor activity 1/159 61/18639 0.0163934426229508 1.92174450974327 0.407520666735913 0.510025443107785 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 1/159 61/18639 0.0163934426229508 1.92174450974327 0.407520666735913 0.510025443107785 GO:0019905 syntaxin binding 1/159 61/18639 0.0163934426229508 1.92174450974327 0.407520666735913 0.510025443107785 GO:0005096 GTPase activator activity 3/159 271/18639 0.011070110701107 1.29770939218826 0.408020354486228 0.510025443107785 GO:0015179 L-amino acid transmembrane transporter activity 1/159 62/18639 0.0161290322580645 1.89074863055386 0.412591407073354 0.51413259448393 GO:0005507 copper ion binding 1/159 63/18639 0.0158730158730159 1.8607367475292 0.417619020050441 0.518781391367007 GO:0019843 rRNA binding 1/159 65/18639 0.0153846153846154 1.80348330914369 0.427546318871701 0.52946912553771 GO:0016500 protein-hormone receptor activity 1/159 67/18639 0.0149253731343284 1.74964798648268 0.437305442636751 0.536811692974133 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 1/159 67/18639 0.0149253731343284 1.74964798648268 0.437305442636751 0.536811692974133 GO:0035091 phosphatidylinositol binding 3/159 284/18639 0.0105633802816901 1.23830720170077 0.437501529773918 0.536811692974133 GO:0008080 N-acetyltransferase activity 1/159 69/18639 0.0144927536231884 1.69893355209188 0.446899222615356 0.546665715737439 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 2/159 181/18639 0.0110497237569061 1.29531950380486 0.458431999648108 0.559063414205009 GO:0004521 RNA endonuclease activity 1/159 73/18639 0.0136986301369863 1.60584130266219 0.46560184024657 0.566081264737472 GO:0031625 ubiquitin protein ligase binding 3/159 302/18639 0.00993377483443709 1.16450081219543 0.47738030818327 0.577367644111819 GO:0017022 myosin binding 1/159 76/18639 0.0131578947368421 1.54245283018868 0.47921514461281 0.577367644111819 GO:0098631 cell adhesion mediator activity 1/159 76/18639 0.0131578947368421 1.54245283018868 0.47921514461281 0.577367644111819 GO:0051540 metal cluster binding 1/159 77/18639 0.012987012987013 1.52242097525116 0.483675888673929 0.580992058467182 GO:0048306 calcium-dependent protein binding 1/159 80/18639 0.0125 1.46533018867925 0.496831583356646 0.595007884259457 GO:0015101 organic cation transmembrane transporter activity 1/159 81/18639 0.0123456790123457 1.44723969252271 0.501142364015426 0.596598052399317 GO:0030971 receptor tyrosine kinase binding 1/159 81/18639 0.0123456790123457 1.44723969252271 0.501142364015426 0.596598052399317 GO:0051117 ATPase binding 1/159 84/18639 0.0119047619047619 1.3955525606469 0.513855737415964 0.609917789217761 GO:0044389 ubiquitin-like protein ligase binding 3/159 322/18639 0.0093167701863354 1.09217156920192 0.520112541128764 0.615157204726597 GO:0003714 transcription corepressor activity 2/159 204/18639 0.00980392156862745 1.14927857935627 0.521345731005791 0.615157204726597 GO:0003924 GTPase activity 3/159 331/18639 0.00906344410876133 1.062475061278 0.538724701981508 0.633793767037069 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 1/159 91/18639 0.010989010989011 1.28820236367406 0.542281979745448 0.636107894129558 GO:0051213 dioxygenase activity 1/159 93/18639 0.010752688172043 1.26049908703591 0.550095994690372 0.641511364070404 GO:0051219 phosphoprotein binding 1/159 93/18639 0.010752688172043 1.26049908703591 0.550095994690372 0.641511364070404 GO:0016407 acetyltransferase activity 1/159 96/18639 0.0104166666666667 1.22110849056604 0.561569141564628 0.652987373912358 GO:0042626 ATPase-coupled transmembrane transporter activity 1/159 98/18639 0.0102040816326531 1.19618790912591 0.569055901859855 0.659774958678093 GO:0015171 amino acid transmembrane transporter activity 1/159 102/18639 0.00980392156862745 1.14927857935627 0.583650398813305 0.673214456870464 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 2/159 229/18639 0.00873362445414847 1.02381148554008 0.584013541335128 0.673214456870464 GO:0003712 transcription coregulator activity 4/159 495/18639 0.00808080808080808 0.947284162378502 0.612752468311332 0.704313181967048 GO:0035401 histone H3Y41 kinase activity 1/159 115/18639 0.00869565217391304 1.01936013125513 0.627774004626245 0.716653815630693 GO:0140801 histone H2AXY142 kinase activity 1/159 115/18639 0.00869565217391304 1.01936013125513 0.627774004626245 0.716653815630693 GO:0005525 GTP binding 3/159 378/18639 0.00793650793650794 0.9303683737646 0.628863723215933 0.716653815630693 GO:1990782 protein tyrosine kinase binding 1/159 117/18639 0.00854700854700855 1.00193517174649 0.634136724955566 0.720609914722234 GO:0019887 protein kinase regulator activity 2/159 255/18639 0.00784313725490196 0.919422863485017 0.642598934658644 0.728157433040957 GO:0004540 RNA nuclease activity 1/159 121/18639 0.00826446280991736 0.968813347887104 0.646539720307453 0.729859118253878 GO:0008528 G protein-coupled peptide receptor activity 1/159 122/18639 0.00819672131147541 0.960872254871636 0.649574615245951 0.729859118253878 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/159 122/18639 0.00819672131147541 0.960872254871636 0.649574615245951 0.729859118253878 GO:0004519 endonuclease activity 1/159 127/18639 0.0078740157480315 0.923042638538107 0.664365016071448 0.737290378763382 GO:0042826 histone deacetylase binding 1/159 127/18639 0.0078740157480315 0.923042638538107 0.664365016071448 0.737290378763382 GO:0019001 guanyl nucleotide binding 3/159 400/18639 0.0075 0.879198113207547 0.666701268608842 0.737290378763382 GO:0032561 guanyl ribonucleotide binding 3/159 400/18639 0.0075 0.879198113207547 0.666701268608842 0.737290378763382 GO:0001653 peptide receptor activity 1/159 128/18639 0.0078125 0.915831367924528 0.667247792780861 0.737290378763382 GO:0031490 chromatin DNA binding 1/159 128/18639 0.0078125 0.915831367924528 0.667247792780861 0.737290378763382 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 2/159 268/18639 0.00746268656716418 0.874823993241341 0.66938198910023 0.737611007272981 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 1/159 130/18639 0.00769230769230769 0.901741654571843 0.67293973738144 0.739494216902681 GO:0005179 hormone activity 1/159 132/18639 0.00757575757575758 0.888078902229846 0.678534919472761 0.741568218003018 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 1/159 132/18639 0.00757575757575758 0.888078902229846 0.678534919472761 0.741568218003018 GO:0051087 protein-folding chaperone binding 1/159 134/18639 0.00746268656716418 0.874823993241341 0.684034973773129 0.745342170331518 GO:0015297 antiporter activity 1/159 135/18639 0.00740740740740741 0.868343815513627 0.686749831334332 0.745342170331518 GO:0001217 DNA-binding transcription repressor activity 2/159 278/18639 0.00719424460431655 0.843355504275825 0.688870313781486 0.745342170331518 GO:0044325 transmembrane transporter binding 1/159 136/18639 0.00735294117647059 0.861958934517203 0.689441507556654 0.745342170331518 GO:0016922 nuclear receptor binding 1/159 137/18639 0.0072992700729927 0.855667263462333 0.692110199136317 0.746210457289829 GO:0004713 protein tyrosine kinase activity 1/159 140/18639 0.00714285714285714 0.83733153638814 0.699980308188098 0.752666998051718 GO:0099106 ion channel regulator activity 1/159 160/18639 0.00625 0.732665094339623 0.747574839563229 0.801688835992739 GO:0015399 primary active transmembrane transporter activity 1/159 166/18639 0.00602409638554217 0.706183223459877 0.76033114342594 0.813188388690845 GO:0016247 channel regulator activity 1/159 168/18639 0.00595238095238095 0.69777628032345 0.764439233379258 0.815401848937875 GO:0141108 transporter regulator activity 1/159 170/18639 0.00588235294117647 0.689567147613762 0.768477343142261 0.817529088449214 GO:0003735 structural constituent of ribosome 1/159 175/18639 0.00571428571428571 0.669865229110512 0.778274179692873 0.825755097817372 GO:0030695 GTPase regulator activity 3/159 489/18639 0.00613496932515337 0.71918046070147 0.791054906705709 0.836097801994686 GO:0060589 nucleoside-triphosphatase regulator activity 3/159 490/18639 0.00612244897959184 0.717712745475549 0.792202667389965 0.836097801994686 GO:1901981 phosphatidylinositol phosphate binding 1/159 185/18639 0.00540540540540541 0.633656297807241 0.796648916535988 0.838577806879988 GO:0046943 carboxylic acid transmembrane transporter activity 1/159 188/18639 0.00531914893617021 0.623544761140104 0.801860268709918 0.841432169441678 GO:0005342 organic acid transmembrane transporter activity 1/159 189/18639 0.00529100529100529 0.620245582509733 0.803567721816802 0.841432169441678 GO:0016829 lyase activity 1/159 200/18639 0.005 0.586132075471698 0.821411509330807 0.85787102802173 GO:0004518 nuclease activity 1/159 209/18639 0.00478468899521531 0.560891938250429 0.834805519251554 0.869589082553702 GO:0015631 tubulin binding 2/159 385/18639 0.00519480519480519 0.608968390100466 0.843585513290136 0.876452481340401 GO:0003713 transcription coactivator activity 1/159 256/18639 0.00390625 0.457915683962264 0.890121770240247 0.922405979523572 GO:0008514 organic anion transmembrane transporter activity 1/159 269/18639 0.00371747211895911 0.435785929718735 0.90185894479654 0.932153948110119 GO:0022804 active transmembrane transporter activity 2/159 457/18639 0.00437636761487965 0.513025886627307 0.904473644965041 0.932447056664991 GO:0008017 microtubule binding 1/159 276/18639 0.0036231884057971 0.42473338802297 0.907653837262657 0.93332014114412 GO:0031267 small GTPase binding 1/159 283/18639 0.00353356890459364 0.414227615174345 0.913108586292332 0.936521626966495 GO:0015291 secondary active transmembrane transporter activity 1/159 287/18639 0.00348432055749129 0.408454407994215 0.916080554250846 0.937166807417745 GO:0051020 GTPase binding 1/159 315/18639 0.00317460317460317 0.37214734950584 0.934238746782352 0.953304843655461 GO:0141003 histone H2AX kinase activity 1/159 354/18639 0.00282485875706215 0.331148065238248 0.953204317654256 0.967689808729182 GO:0140996 histone H3 kinase activity 1/159 357/18639 0.00280112044817927 0.328365308387506 0.954414555688946 0.967689808729182 GO:0035173 histone kinase activity 1/159 360/18639 0.00277777777777778 0.32562893081761 0.955593686120067 0.967689808729182 GO:0140098 catalytic activity, acting on RNA 1/159 387/18639 0.00258397932816537 0.302910633318707 0.964930707118286 0.974677481937663 GO:0016887 ATP hydrolysis activity 1/159 417/18639 0.00239808153477218 0.281118501425275 0.973032564827504 0.980385455745596 GO:0004674 protein serine/threonine kinase activity 1/159 433/18639 0.0023094688221709 0.270730750795242 0.976562251613405 0.981469599611462 GO:0046873 metal ion transmembrane transporter activity 1/159 450/18639 0.00222222222222222 0.260503144654088 0.979810505435818 0.982266170862975 GO:0016755 aminoacyltransferase activity 1/159 496/18639 0.00201612903225806 0.236343578819233 0.98652574617695 0.98652574617695