ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0023026 MHC class II protein complex binding 13/362 27/18639 0.481481481481481 24.7909760589319 7.08707227883264e-16 5.01056010113468e-13 GO:0023023 MHC protein complex binding 13/362 37/18639 0.351351351351351 18.0907122592205 1.05622602522255e-13 3.73375899916172e-11 GO:0042277 peptide binding 23/362 249/18639 0.0923694779116466 4.75600745523531 6.91917665624208e-10 1.63061929865438e-07 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 12/362 68/18639 0.176470588235294 9.08628534286643 6.58215573953848e-09 1.04055626646108e-06 GO:0009055 electron transfer activity 15/362 116/18639 0.129310344827586 6.65805391503144 7.35895520835276e-09 1.04055626646108e-06 GO:0022853 active monoatomic ion transmembrane transporter activity 15/362 118/18639 0.127118644067797 6.54520554359022 9.33647879525957e-09 1.10014841804142e-06 GO:0042605 peptide antigen binding 10/362 45/18639 0.222222222222222 11.4419889502762 1.17582471934912e-08 1.18758296654261e-06 GO:0008137 NADH dehydrogenase (ubiquinone) activity 9/362 41/18639 0.219512195121951 11.3024524996631 7.20822201246798e-08 6.37026620351857e-06 GO:0003954 NADH dehydrogenase activity 9/362 44/18639 0.204545454545455 10.5318307383225 1.38556930440382e-07 1.08844166468167e-05 GO:0044183 protein folding chaperone 11/362 75/18639 0.146666666666667 7.55171270718232 2.05489879797243e-07 1.45281345016651e-05 GO:0031625 ubiquitin protein ligase binding 21/362 302/18639 0.0695364238410596 3.58035746954008 5.12716153959566e-07 3.29536655317648e-05 GO:0032395 MHC class II receptor activity 5/362 10/18639 0.5 25.7444751381215 6.25313166065529e-07 3.50014304073943e-05 GO:0051082 unfolded protein binding 13/362 121/18639 0.107438016528926 5.53187069083604 6.69216550033052e-07 3.50014304073943e-05 GO:0015078 proton transmembrane transporter activity 16/362 185/18639 0.0864864864864865 4.45309840226967 6.9309763182959e-07 3.50014304073943e-05 GO:0015399 primary active transmembrane transporter activity 15/362 166/18639 0.0903614457831325 4.65261598881715 8.86885289826173e-07 4.18018599938069e-05 GO:0044389 ubiquitin-like protein ligase binding 21/362 322/18639 0.0652173913043478 3.35797501801585 1.44861393510396e-06 6.40106282574064e-05 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 9/362 58/18639 0.155172413793103 7.98966469803772 1.6381313521136e-06 6.79434110562412e-05 GO:0033218 amide binding 18/362 247/18639 0.0728744939271255 3.75223119422014 1.72981810327064e-06 6.79434110562412e-05 GO:0008009 chemokine activity 8/362 45/18639 0.177777777777778 9.15359116022099 2.15685885254608e-06 7.87563562421296e-05 GO:0140375 immune receptor activity 14/362 156/18639 0.0897435897435897 4.62080322991925 2.22790258110692e-06 7.87563562421296e-05 GO:0016651 oxidoreductase activity, acting on NAD(P)H 10/362 88/18639 0.113636363636364 5.8510170768458 7.93352403416392e-06 0.000267095309150185 GO:0045296 cadherin binding 20/362 334/18639 0.0598802395209581 3.08317067522414 9.2724349387944e-06 0.00029798234098762 GO:0140313 molecular sequestering activity 8/362 55/18639 0.145454545454545 7.48930185836263 1.02882433238811e-05 0.000298608872506792 GO:0042379 chemokine receptor binding 9/362 72/18639 0.125 6.43611878453039 1.03106471424335e-05 0.000298608872506792 GO:0140662 ATP-dependent protein folding chaperone 7/362 40/18639 0.175 9.01056629834254 1.05590124648795e-05 0.000298608872506792 GO:0005126 cytokine receptor binding 17/362 275/18639 0.0618181818181818 3.18295328980412 2.90146929048395e-05 0.000768666674042534 GO:0071813 lipoprotein particle binding 6/362 32/18639 0.1875 9.65417817679558 3.0442244516536e-05 0.000768666674042534 GO:0071814 protein-lipid complex binding 6/362 32/18639 0.1875 9.65417817679558 3.0442244516536e-05 0.000768666674042534 GO:0001540 amyloid-beta binding 9/362 83/18639 0.108433734939759 5.58313918658058 3.30160213281368e-05 0.000804907830310094 GO:0140311 protein sequestering activity 6/362 33/18639 0.181818181818182 9.36162732295329 3.66028516282453e-05 0.000862607203372314 GO:0019864 IgG binding 4/362 11/18639 0.363636363636364 18.7232546459066 4.14550630835346e-05 0.000945442890324483 GO:0048020 CCR chemokine receptor binding 7/362 50/18639 0.14 7.20845303867403 4.78888245014267e-05 0.0010580437163284 GO:0051087 protein-folding chaperone binding 11/362 134/18639 0.082089552238806 4.22670487342294 6.22242349053179e-05 0.00133310709327454 GO:0019865 immunoglobulin binding 5/362 26/18639 0.192307692307692 9.90172120696983 0.000126345645377517 0.00262724621417366 GO:0001530 lipopolysaccharide binding 6/362 41/18639 0.146341463414634 7.53496833310875 0.000130376656858043 0.00263360846853247 GO:0001786 phosphatidylserine binding 7/362 59/18639 0.11864406779661 6.10885850735088 0.000140838751045628 0.00276591658303498 GO:0048306 calcium-dependent protein binding 8/362 80/18639 0.1 5.14889502762431 0.000160757846167942 0.00307177830380365 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 18/362 349/18639 0.0515759312320917 2.6555905586601 0.000175115042450347 0.00325806144769462 GO:0016209 antioxidant activity 8/362 86/18639 0.0930232558139535 4.78966979313889 0.000266063506523979 0.0047006227377459 GO:0030169 low-density lipoprotein particle binding 4/362 17/18639 0.235294117647059 12.1150471238219 0.000272596226658532 0.0047006227377459 GO:0036041 long-chain fatty acid binding 4/362 17/18639 0.235294117647059 12.1150471238219 0.000272596226658532 0.0047006227377459 GO:0005504 fatty acid binding 6/362 47/18639 0.127659574468085 6.57305748207359 0.000282318397971714 0.00475235969919051 GO:0072341 modified amino acid binding 8/362 91/18639 0.0879120879120879 4.52650112318621 0.000391884276588276 0.00644330659413746 GO:0005125 cytokine activity 13/362 234/18639 0.0555555555555556 2.86049723756906 0.000690683634781871 0.0110980302225178 GO:0031072 heat shock protein binding 9/362 131/18639 0.0687022900763359 3.53740879760449 0.00105305441530387 0.0160594457835739 GO:0010854 adenylate cyclase regulator activity 3/362 11/18639 0.272727272727273 14.0424409844299 0.0010676010634059 0.0160594457835739 GO:0050786 RAGE receptor binding 3/362 11/18639 0.272727272727273 14.0424409844299 0.0010676010634059 0.0160594457835739 GO:0140297 DNA-binding transcription factor binding 20/362 488/18639 0.040983606557377 2.1102028801739 0.00146054362198719 0.0215125904321864 GO:0005200 structural constituent of cytoskeleton 8/362 112/18639 0.0714285714285714 3.67778216258879 0.0015434732664628 0.0222701142732489 GO:0008035 high-density lipoprotein particle binding 3/362 13/18639 0.230769230769231 11.8820654483638 0.00179784741877489 0.0239826061334688 GO:0019855 calcium channel inhibitor activity 3/362 13/18639 0.230769230769231 11.8820654483638 0.00179784741877489 0.0239826061334688 GO:0031994 insulin-like growth factor I binding 3/362 13/18639 0.230769230769231 11.8820654483638 0.00179784741877489 0.0239826061334688 GO:0035325 Toll-like receptor binding 3/362 13/18639 0.230769230769231 11.8820654483638 0.00179784741877489 0.0239826061334688 GO:0050840 extracellular matrix binding 6/362 67/18639 0.0895522388059701 4.61095077100684 0.00189642402450058 0.0248291071355909 GO:0019955 cytokine binding 9/362 144/18639 0.0625 3.21805939226519 0.00203441379469689 0.0261514645972855 GO:0001664 G protein-coupled receptor binding 14/362 297/18639 0.0471380471380471 2.42708856521011 0.00210542890144273 0.0265810398807145 GO:0003823 antigen binding 10/362 174/18639 0.0574712643678161 2.9591350733473 0.00218208502069294 0.0266758903107365 GO:0019763 immunoglobulin receptor activity 3/362 14/18639 0.214285714285714 11.0333464877664 0.00225542430668763 0.0266758903107365 GO:0044548 S100 protein binding 3/362 14/18639 0.214285714285714 11.0333464877664 0.00225542430668763 0.0266758903107365 GO:0043236 laminin binding 4/362 29/18639 0.137931034482759 7.10192417603353 0.0022638662215618 0.0266758903107365 GO:0043021 ribonucleoprotein complex binding 10/362 177/18639 0.0564971751412429 2.90898024159565 0.00247182107179862 0.0286488114387151 GO:0060590 ATPase regulator activity 5/362 49/18639 0.102040816326531 5.25397451798399 0.00254292646773924 0.0288707786021175 GO:0001968 fibronectin binding 4/362 30/18639 0.133333333333333 6.86519337016575 0.00257264363781245 0.0288707786021175 GO:0031386 protein tag activity 3/362 15/18639 0.2 10.2977900552486 0.00277897415941513 0.0297687080410076 GO:0140776 protein-containing complex destabilizing activity 3/362 15/18639 0.2 10.2977900552486 0.00277897415941513 0.0297687080410076 GO:0141047 molecular tag activity 3/362 15/18639 0.2 10.2977900552486 0.00277897415941513 0.0297687080410076 GO:0005246 calcium channel regulator activity 5/362 53/18639 0.0943396226415094 4.85744813926822 0.00359309346067885 0.0379151802492529 GO:0140416 transcription regulator inhibitor activity 4/362 33/18639 0.121212121212121 6.24108488196886 0.00366991034923352 0.0381562737780603 GO:0022804 active transmembrane transporter activity 18/362 457/18639 0.0393873085339169 2.02801117061789 0.00377144971878399 0.0386436949446417 GO:0008429 phosphatidylethanolamine binding 3/362 17/18639 0.176470588235294 9.08628534286643 0.00403546030380996 0.0407581490684806 GO:0033293 monocarboxylic acid binding 6/362 79/18639 0.0759493670886076 3.91055318553745 0.00435231945621894 0.0433392937400957 GO:0098641 cadherin binding involved in cell-cell adhesion 3/362 18/18639 0.166666666666667 8.58149171270718 0.00477352481504415 0.046873361725503 GO:0019888 protein phosphatase regulator activity 7/362 107/18639 0.0654205607476635 3.36843599938039 0.00487984893940969 0.0470345333530948 GO:0004601 peroxidase activity 5/362 57/18639 0.087719298245614 4.51657458563536 0.00492299217557145 0.0470345333530948 GO:0019838 growth factor binding 8/362 136/18639 0.0588235294117647 3.02876178095548 0.00512629057200645 0.0483238324587808 GO:0043394 proteoglycan binding 4/362 37/18639 0.108108108108108 5.56637300283709 0.00557421410716277 0.0513065248974018 GO:0005520 insulin-like growth factor binding 3/362 19/18639 0.157894736842105 8.12983425414365 0.00558783934526158 0.0513065248974018 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 5/362 59/18639 0.0847457627118644 4.36347036239348 0.00570428589276837 0.0517042323870159 GO:0070851 growth factor receptor binding 8/362 139/18639 0.0575539568345324 2.96339282165428 0.00583494315112025 0.0522190482005319 GO:0043022 ribosome binding 7/362 112/18639 0.0625 3.21805939226519 0.00624758465951471 0.0552130294284612 GO:0010851 cyclase regulator activity 3/362 20/18639 0.15 7.72334254143646 0.00648040823099391 0.0565635632013913 GO:0003735 structural constituent of ribosome 9/362 175/18639 0.0514285714285714 2.64800315706393 0.00732573475022243 0.0631621276635032 GO:0072542 protein phosphatase activator activity 3/362 21/18639 0.142857142857143 7.35556432517758 0.00745302926049617 0.063485442014106 GO:0019208 phosphatase regulator activity 7/362 117/18639 0.0598290598290598 3.08053548661283 0.00788256615411908 0.0663449317971689 GO:0140517 protein-RNA adaptor activity 3/362 22/18639 0.136363636363636 7.02122049221497 0.00850730281277812 0.0704277549406307 GO:0038024 cargo receptor activity 5/362 65/18639 0.0769230769230769 3.96068848278793 0.0085668839107415 0.0704277549406307 GO:0042056 chemoattractant activity 4/362 42/18639 0.0952380952380952 4.90370955011839 0.00875838786848869 0.0711744853220863 GO:0030246 carbohydrate binding 12/362 280/18639 0.0428571428571429 2.20666929755328 0.00888989968652708 0.0714222622542574 GO:0008200 ion channel inhibitor activity 4/362 43/18639 0.0930232558139535 4.78966979313889 0.00951193484322187 0.074721532601754 GO:0048156 tau protein binding 4/362 43/18639 0.0930232558139535 4.78966979313889 0.00951193484322187 0.074721532601754 GO:0004602 glutathione peroxidase activity 3/362 23/18639 0.130434782608696 6.71595003603171 0.0096446406851163 0.0749314391689805 GO:0016248 channel inhibitor activity 4/362 44/18639 0.0909090909090909 4.68081366147664 0.0103064029522008 0.0784260066117585 GO:1990841 promoter-specific chromatin binding 5/362 68/18639 0.0735294117647059 3.78595222619435 0.0103162922417165 0.0784260066117585 GO:0019957 C-C chemokine binding 3/362 24/18639 0.125 6.43611878453039 0.0108662746183212 0.0792005789191041 GO:0042625 ATPase-coupled ion transmembrane transporter activity 3/362 24/18639 0.125 6.43611878453039 0.0108662746183212 0.0792005789191041 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 3/362 24/18639 0.125 6.43611878453039 0.0108662746183212 0.0792005789191041 GO:0046961 proton-transporting ATPase activity, rotational mechanism 3/362 24/18639 0.125 6.43611878453039 0.0108662746183212 0.0792005789191041 GO:0141110 transporter inhibitor activity 4/362 45/18639 0.0888888888888889 4.5767955801105 0.0111425882049264 0.0803858149069692 GO:0019211 phosphatase activator activity 3/362 25/18639 0.12 6.17867403314917 0.0121732645287799 0.0860649802184738 GO:0120020 cholesterol transfer activity 3/362 25/18639 0.12 6.17867403314917 0.0121732645287799 0.0860649802184738 GO:0050750 low-density lipoprotein particle receptor binding 3/362 26/18639 0.115384615384615 5.9410327241819 0.0135665064560473 0.0940345104355433 GO:0070412 R-SMAD binding 3/362 26/18639 0.115384615384615 5.9410327241819 0.0135665064560473 0.0940345104355433 GO:0001671 ATPase activator activity 3/362 27/18639 0.111111111111111 5.72099447513812 0.0150467402345193 0.102288897555819 GO:0004364 glutathione transferase activity 3/362 27/18639 0.111111111111111 5.72099447513812 0.0150467402345193 0.102288897555819 GO:0030957 Tat protein binding 2/362 10/18639 0.2 10.2977900552486 0.0152696171845342 0.102815422375864 GO:0098631 cell adhesion mediator activity 5/362 76/18639 0.0657894736842105 3.38743093922652 0.0161406987534891 0.107655415270913 GO:0004857 enzyme inhibitor activity 15/362 416/18639 0.0360576923076923 1.85657272630684 0.0164785007835733 0.108763812282614 GO:0097718 disordered domain specific binding 3/362 28/18639 0.107142857142857 5.51667324388319 0.0166145568974855 0.108763812282614 GO:0008013 beta-catenin binding 6/362 106/18639 0.0566037735849057 2.91446888356093 0.0173383713167666 0.111341144292941 GO:0005543 phospholipid binding 17/362 497/18639 0.03420523138833 1.76119145814111 0.0177708303839175 0.111341144292941 GO:0003785 actin monomer binding 3/362 29/18639 0.103448275862069 5.32644313202515 0.0182704058216306 0.111341144292941 GO:0005536 D-glucose binding 2/362 11/18639 0.181818181818182 9.36162732295329 0.0184256207670072 0.111341144292941 GO:0008199 ferric iron binding 2/362 11/18639 0.181818181818182 9.36162732295329 0.0184256207670072 0.111341144292941 GO:0008432 JUN kinase binding 2/362 11/18639 0.181818181818182 9.36162732295329 0.0184256207670072 0.111341144292941 GO:0042608 T cell receptor binding 2/362 11/18639 0.181818181818182 9.36162732295329 0.0184256207670072 0.111341144292941 GO:0050998 nitric-oxide synthase binding 2/362 11/18639 0.181818181818182 9.36162732295329 0.0184256207670072 0.111341144292941 GO:0070990 snRNP binding 2/362 11/18639 0.181818181818182 9.36162732295329 0.0184256207670072 0.111341144292941 GO:0046332 SMAD binding 5/362 79/18639 0.0632911392405063 3.25879432128121 0.0187934637333918 0.112601515758542 GO:0016860 intramolecular oxidoreductase activity 4/362 53/18639 0.0754716981132075 3.88595851141457 0.0194176918454029 0.115363933905041 GO:0001965 G-protein alpha-subunit binding 3/362 30/18639 0.1 5.14889502762431 0.0200146016198326 0.11791936121018 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 4/362 54/18639 0.0740740740740741 3.81399631675875 0.0206592748836327 0.120030577920045 GO:0001618 virus receptor activity 5/362 81/18639 0.0617283950617284 3.17833026396562 0.0207124901078437 0.120030577920045 GO:0140272 exogenous protein binding 5/362 82/18639 0.0609756097560976 3.13957013879531 0.0217182044674258 0.120291769342239 GO:0004859 phospholipase inhibitor activity 2/362 12/18639 0.166666666666667 8.58149171270718 0.0218301333711019 0.120291769342239 GO:0008179 adenylate cyclase binding 2/362 12/18639 0.166666666666667 8.58149171270718 0.0218301333711019 0.120291769342239 GO:0010853 cyclase activator activity 2/362 12/18639 0.166666666666667 8.58149171270718 0.0218301333711019 0.120291769342239 GO:0035259 nuclear glucocorticoid receptor binding 2/362 12/18639 0.166666666666667 8.58149171270718 0.0218301333711019 0.120291769342239 GO:0070325 lipoprotein particle receptor binding 3/362 31/18639 0.0967741935483871 4.98280163963643 0.0218473307898878 0.120291769342239 GO:0098632 cell-cell adhesion mediator activity 4/362 55/18639 0.0727272727272727 3.74465092918132 0.0219485689464623 0.120291769342239 GO:0120015 sterol transfer activity 3/362 32/18639 0.09375 4.82708908839779 0.023768658126581 0.129264933042252 GO:0031432 titin binding 2/362 13/18639 0.153846153846154 7.92137696557586 0.0254723671806159 0.137033253859784 GO:0019209 kinase activator activity 7/362 148/18639 0.0472972972972973 2.43528818874123 0.0256910065360203 0.137033253859784 GO:0019956 chemokine binding 3/362 33/18639 0.0909090909090909 4.68081366147664 0.0257785329043158 0.137033253859784 GO:0045309 protein phosphorylated amino acid binding 4/362 59/18639 0.0677966101694915 3.49077628991479 0.027590358130332 0.145570023866751 GO:0015035 protein-disulfide reductase activity 3/362 34/18639 0.0882352941176471 4.54314267143321 0.0278767948373165 0.14599180703691 GO:0031406 carboxylic acid binding 8/362 187/18639 0.0427807486631016 2.20273584069489 0.0300052199663909 0.155143563034489 GO:0005154 epidermal growth factor receptor binding 3/362 35/18639 0.0857142857142857 4.41333859510655 0.030063179824222 0.155143563034489 GO:0015026 coreceptor activity 4/362 61/18639 0.0655737704918033 3.37632460827824 0.030706292306006 0.157314120727147 GO:0043177 organic acid binding 8/362 189/18639 0.0423280423280423 2.17942646671928 0.0316738634136069 0.161103751319569 GO:0000774 adenyl-nucleotide exchange factor activity 2/362 15/18639 0.133333333333333 6.86519337016575 0.0334284551211715 0.165272152242435 GO:0004129 cytochrome-c oxidase activity 2/362 15/18639 0.133333333333333 6.86519337016575 0.0334284551211715 0.165272152242435 GO:0016846 carbon-sulfur lyase activity 2/362 15/18639 0.133333333333333 6.86519337016575 0.0334284551211715 0.165272152242435 GO:0017081 chloride channel regulator activity 2/362 15/18639 0.133333333333333 6.86519337016575 0.0334284551211715 0.165272152242435 GO:0051219 phosphoprotein binding 5/362 93/18639 0.0537634408602151 2.76822313313135 0.0349036698860936 0.171367323676862 GO:0042826 histone deacetylase binding 6/362 127/18639 0.047244094488189 2.43254883194849 0.0376773570672514 0.180200525444415 GO:0000062 fatty-acyl-CoA binding 2/362 16/18639 0.125 6.43611878453039 0.0377223165003866 0.180200525444415 GO:0016675 oxidoreductase activity, acting on a heme group of donors 2/362 16/18639 0.125 6.43611878453039 0.0377223165003866 0.180200525444415 GO:0055102 lipase inhibitor activity 2/362 16/18639 0.125 6.43611878453039 0.0377223165003866 0.180200525444415 GO:0008083 growth factor activity 7/362 162/18639 0.0432098765432099 2.22483118477594 0.03910945503704 0.184760197419447 GO:0004896 cytokine receptor activity 5/362 96/18639 0.0520833333333333 2.68171616022099 0.0391994761144512 0.184760197419447 GO:0051787 misfolded protein binding 2/362 17/18639 0.117647058823529 6.05752356191095 0.0422138973265968 0.192947692148108 GO:0070492 oligosaccharide binding 2/362 17/18639 0.117647058823529 6.05752356191095 0.0422138973265968 0.192947692148108 GO:1901567 fatty acid derivative binding 2/362 17/18639 0.117647058823529 6.05752356191095 0.0422138973265968 0.192947692148108 GO:1990226 histone methyltransferase binding 2/362 17/18639 0.117647058823529 6.05752356191095 0.0422138973265968 0.192947692148108 GO:0015036 disulfide oxidoreductase activity 3/362 40/18639 0.075 3.86167127071823 0.04230112062653 0.192947692148108 GO:0034185 apolipoprotein binding 2/362 18/18639 0.111111111111111 5.72099447513812 0.0468939438905409 0.209835559054509 GO:0035615 clathrin adaptor activity 2/362 18/18639 0.111111111111111 5.72099447513812 0.0468939438905409 0.209835559054509 GO:1901611 phosphatidylglycerol binding 2/362 18/18639 0.111111111111111 5.72099447513812 0.0468939438905409 0.209835559054509 GO:0044325 transmembrane transporter binding 6/362 136/18639 0.0441176470588235 2.27157133571661 0.0497210224751733 0.221086559056274 GO:0005518 collagen binding 4/362 72/18639 0.0555555555555556 2.86049723756906 0.0514224143897939 0.223108014149009 GO:0003756 protein disulfide isomerase activity 2/362 19/18639 0.105263157894737 5.41988950276243 0.0517534856017503 0.223108014149009 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 2/362 19/18639 0.105263157894737 5.41988950276243 0.0517534856017503 0.223108014149009 GO:0097001 ceramide binding 2/362 19/18639 0.105263157894737 5.41988950276243 0.0517534856017503 0.223108014149009 GO:0120227 acyl-CoA binding 2/362 19/18639 0.105263157894737 5.41988950276243 0.0517534856017503 0.223108014149009 GO:0043539 protein serine/threonine kinase activator activity 4/362 73/18639 0.0547945205479452 2.82131234390373 0.0536063340805575 0.229695019363358 GO:0030295 protein kinase activator activity 6/362 139/18639 0.0431654676258993 2.22254461624071 0.0542048561756688 0.230574004102063 GO:0019207 kinase regulator activity 10/362 287/18639 0.0348432055749129 1.79404007931161 0.0544637322277858 0.230574004102063 GO:0016408 C-acyltransferase activity 2/362 20/18639 0.1 5.14889502762431 0.0567838275318343 0.237551278491165 GO:0043024 ribosomal small subunit binding 2/362 20/18639 0.1 5.14889502762431 0.0567838275318343 0.237551278491165 GO:0001216 DNA-binding transcription activator activity 15/362 491/18639 0.0305498981670061 1.57298218766527 0.0571601521845918 0.237718985850038 GO:0019887 protein kinase regulator activity 9/362 255/18639 0.0352941176470588 1.81725706857329 0.0618281189317151 0.254025142940545 GO:0140312 cargo adaptor activity 2/362 21/18639 0.0952380952380952 4.90370955011839 0.0619765431393436 0.254025142940545 GO:0016853 isomerase activity 7/362 180/18639 0.0388888888888889 2.00234806629834 0.0621589105073753 0.254025142940545 GO:0001784 phosphotyrosine residue binding 3/362 47/18639 0.0638297872340425 3.28652874103679 0.0629581837745256 0.255812850164308 GO:0030021 extracellular matrix structural constituent conferring compression resistance 2/362 22/18639 0.0909090909090909 4.68081366147664 0.0673234671720002 0.270441427787523 GO:0061133 endopeptidase activator activity 2/362 22/18639 0.0909090909090909 4.68081366147664 0.0673234671720002 0.270441427787523 GO:0005212 structural constituent of eye lens 2/362 23/18639 0.0869565217391304 4.47730002402114 0.0728166887421796 0.289221342363601 GO:0016493 C-C chemokine receptor activity 2/362 23/18639 0.0869565217391304 4.47730002402114 0.0728166887421796 0.289221342363601 GO:0015631 tubulin binding 12/362 385/18639 0.0311688311688312 1.60485039822056 0.0738112115500195 0.291533667965719 GO:0030544 Hsp70 protein binding 3/362 51/18639 0.0588235294117647 3.02876178095548 0.0764906169438275 0.298188822645894 GO:0019902 phosphatase binding 7/362 190/18639 0.0368421052631579 1.89696132596685 0.0779212280283644 0.298188822645894 GO:0015149 hexose transmembrane transporter activity 2/362 24/18639 0.0833333333333333 4.29074585635359 0.0784485445716213 0.298188822645894 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 2/362 24/18639 0.0833333333333333 4.29074585635359 0.0784485445716213 0.298188822645894 GO:0048027 mRNA 5'-UTR binding 2/362 24/18639 0.0833333333333333 4.29074585635359 0.0784485445716213 0.298188822645894 GO:0050431 transforming growth factor beta binding 2/362 24/18639 0.0833333333333333 4.29074585635359 0.0784485445716213 0.298188822645894 GO:0055056 D-glucose transmembrane transporter activity 2/362 24/18639 0.0833333333333333 4.29074585635359 0.0784485445716213 0.298188822645894 GO:0004864 protein phosphatase inhibitor activity 3/362 53/18639 0.0566037735849057 2.91446888356093 0.0836964170502496 0.313355841935861 GO:0017046 peptide hormone binding 3/362 53/18639 0.0566037735849057 2.91446888356093 0.0836964170502496 0.313355841935861 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 2/362 25/18639 0.08 4.11911602209945 0.0842116124014335 0.313355841935861 GO:0016895 DNA exonuclease activity, producing 5'-phosphomonoesters 2/362 25/18639 0.08 4.11911602209945 0.0842116124014335 0.313355841935861 GO:0003925 G protein activity 3/362 54/18639 0.0555555555555556 2.86049723756906 0.0874044842365212 0.318498920632146 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 3/362 54/18639 0.0555555555555556 2.86049723756906 0.0874044842365212 0.318498920632146 GO:0001637 G protein-coupled chemoattractant receptor activity 2/362 26/18639 0.0769230769230769 3.96068848278793 0.090098704563549 0.318498920632146 GO:0004529 DNA exonuclease activity 2/362 26/18639 0.0769230769230769 3.96068848278793 0.090098704563549 0.318498920632146 GO:0004950 chemokine receptor activity 2/362 26/18639 0.0769230769230769 3.96068848278793 0.090098704563549 0.318498920632146 GO:0008157 protein phosphatase 1 binding 2/362 26/18639 0.0769230769230769 3.96068848278793 0.090098704563549 0.318498920632146 GO:0008198 ferrous iron binding 2/362 26/18639 0.0769230769230769 3.96068848278793 0.090098704563549 0.318498920632146 GO:0015145 monosaccharide transmembrane transporter activity 2/362 26/18639 0.0769230769230769 3.96068848278793 0.090098704563549 0.318498920632146 GO:0030247 polysaccharide binding 2/362 26/18639 0.0769230769230769 3.96068848278793 0.090098704563549 0.318498920632146 GO:0050681 nuclear androgen receptor binding 2/362 26/18639 0.0769230769230769 3.96068848278793 0.090098704563549 0.318498920632146 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 14/362 484/18639 0.0289256198347107 1.48934980137893 0.090906820646419 0.319756826850837 GO:0004197 cysteine-type endopeptidase activity 4/362 88/18639 0.0454545454545455 2.34040683073832 0.0921741922304046 0.321110795476939 GO:0099106 ion channel regulator activity 6/362 160/18639 0.0375 1.93083563535912 0.0922440402458798 0.321110795476939 GO:0003779 actin binding 13/362 443/18639 0.0293453724604966 1.51096242345634 0.0926543172238975 0.321110795476939 GO:0019212 phosphatase inhibitor activity 3/362 56/18639 0.0535714285714286 2.75833662194159 0.0950238895729653 0.327716536234568 GO:0016504 peptidase activator activity 3/362 57/18639 0.0526315789473684 2.70994475138122 0.0989323355935717 0.339539617789588 GO:0005539 glycosaminoglycan binding 8/362 242/18639 0.0330578512396694 1.70211405871878 0.100526715929592 0.342500777789933 GO:0046625 sphingolipid binding 2/362 28/18639 0.0714285714285714 3.67778216258879 0.10221734669544 0.342500777789933 GO:0046875 ephrin receptor binding 2/362 28/18639 0.0714285714285714 3.67778216258879 0.10221734669544 0.342500777789933 GO:0051119 sugar transmembrane transporter activity 2/362 28/18639 0.0714285714285714 3.67778216258879 0.10221734669544 0.342500777789933 GO:0141052 histone H3 demethylase activity 2/362 28/18639 0.0714285714285714 3.67778216258879 0.10221734669544 0.342500777789933 GO:0046982 protein heterodimerization activity 11/362 369/18639 0.029810298102981 1.53490095674437 0.10649060297504 0.355136114638457 GO:0051213 dioxygenase activity 4/362 93/18639 0.043010752688172 2.21457850650508 0.107319412656562 0.356219834498543 GO:0051861 glycolipid binding 2/362 29/18639 0.0689655172413793 3.55096208801676 0.108435638612018 0.358242974292975 GO:0016247 channel regulator activity 6/362 168/18639 0.0357142857142857 1.8388910812944 0.109742714511955 0.360874879813732 GO:0042562 hormone binding 4/362 94/18639 0.0425531914893617 2.1910191606912 0.110475762703914 0.361603538109572 GO:0051015 actin filament binding 7/362 209/18639 0.0334928229665072 1.7245102963335 0.113693651324566 0.366843329270359 GO:0141108 transporter regulator activity 6/362 170/18639 0.0352941176470588 1.81725706857329 0.114366171788891 0.366843329270359 GO:0031210 phosphatidylcholine binding 2/362 30/18639 0.0666666666666667 3.43259668508287 0.114751426968603 0.366843329270359 GO:0032452 histone demethylase activity 2/362 30/18639 0.0666666666666667 3.43259668508287 0.114751426968603 0.366843329270359 GO:0035925 mRNA 3'-UTR AU-rich region binding 2/362 30/18639 0.0666666666666667 3.43259668508287 0.114751426968603 0.366843329270359 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 3/362 61/18639 0.0491803278688525 2.53224345620868 0.115189843137227 0.366843329270359 GO:0008201 heparin binding 6/362 172/18639 0.0348837209302326 1.79612617242708 0.119086702990225 0.377552910377081 GO:0140457 protein demethylase activity 2/362 31/18639 0.0645161290322581 3.32186775975762 0.121158606015411 0.382406850236139 GO:0002020 protease binding 5/362 136/18639 0.0367647058823529 1.89297611309717 0.125821658855791 0.395359612493529 GO:0016922 nuclear receptor binding 5/362 137/18639 0.0364963503649635 1.87915876920595 0.128648641351182 0.402453935554361 GO:0120013 lipid transfer activity 3/362 65/18639 0.0461538461538462 2.37641308967276 0.132372530052912 0.412279201530436 GO:0008238 exopeptidase activity 4/362 102/18639 0.0392156862745098 2.01917452063698 0.137155616097292 0.425302721845549 GO:0090482 vitamin transmembrane transporter activity 2/362 34/18639 0.0588235294117647 3.02876178095548 0.140870385618919 0.434914247303825 GO:0043015 gamma-tubulin binding 2/362 35/18639 0.0571428571428571 2.94222573007103 0.147585973848901 0.453666450048578 GO:0019903 protein phosphatase binding 5/362 144/18639 0.0347222222222222 1.78781077348066 0.149225522959198 0.456720539966032 GO:0061134 peptidase regulator activity 7/362 226/18639 0.0309734513274336 1.59479049528187 0.151845469423696 0.462735977942038 GO:0097110 scaffold protein binding 3/362 70/18639 0.0428571428571429 2.20666929755328 0.15500176796286 0.470327253003186 GO:0005096 GTPase activator activity 8/362 271/18639 0.029520295202952 1.51996901184481 0.158821858972951 0.479859206384088 GO:0004620 phospholipase activity 4/362 109/18639 0.036697247706422 1.88950276243094 0.162404673864457 0.488596189030515 GO:1901681 sulfur compound binding 8/362 275/18639 0.0290909090909091 1.49786037167253 0.167912655368133 0.493065596231673 GO:0048029 monosaccharide binding 3/362 74/18639 0.0405405405405405 2.08738987606391 0.173905348815991 0.493065596231673 GO:0046906 tetrapyrrole binding 5/362 152/18639 0.0328947368421053 1.69371546961326 0.174313350243012 0.493065596231673 GO:0001217 DNA-binding transcription repressor activity 8/362 278/18639 0.0287769784172662 1.48169641082714 0.174883928315095 0.493065596231673 GO:0008236 serine-type peptidase activity 6/362 194/18639 0.0309278350515464 1.59244176112092 0.176969694195366 0.493065596231673 GO:0000182 rDNA binding 1/362 10/18639 0.1 5.14889502762431 0.178131641389212 0.493065596231673 GO:0003796 lysozyme activity 1/362 10/18639 0.1 5.14889502762431 0.178131641389212 0.493065596231673 GO:0005345 purine nucleobase transmembrane transporter activity 1/362 10/18639 0.1 5.14889502762431 0.178131641389212 0.493065596231673 GO:0005381 iron ion transmembrane transporter activity 1/362 10/18639 0.1 5.14889502762431 0.178131641389212 0.493065596231673 GO:0008140 cAMP response element binding protein binding 1/362 10/18639 0.1 5.14889502762431 0.178131641389212 0.493065596231673 GO:0008239 dipeptidyl-peptidase activity 1/362 10/18639 0.1 5.14889502762431 0.178131641389212 0.493065596231673 GO:0008297 single-stranded DNA exodeoxyribonuclease activity 1/362 10/18639 0.1 5.14889502762431 0.178131641389212 0.493065596231673 GO:0015187 glycine transmembrane transporter activity 1/362 10/18639 0.1 5.14889502762431 0.178131641389212 0.493065596231673 GO:0015658 branched-chain amino acid transmembrane transporter activity 1/362 10/18639 0.1 5.14889502762431 0.178131641389212 0.493065596231673 GO:0016175 superoxide-generating NAD(P)H oxidase activity 1/362 10/18639 0.1 5.14889502762431 0.178131641389212 0.493065596231673 GO:0031419 cobalamin binding 1/362 10/18639 0.1 5.14889502762431 0.178131641389212 0.493065596231673 GO:0031996 thioesterase binding 1/362 10/18639 0.1 5.14889502762431 0.178131641389212 0.493065596231673 GO:0035374 chondroitin sulfate binding 1/362 10/18639 0.1 5.14889502762431 0.178131641389212 0.493065596231673 GO:0050815 phosphoserine residue binding 1/362 10/18639 0.1 5.14889502762431 0.178131641389212 0.493065596231673 GO:0098505 G-rich strand telomeric DNA binding 1/362 10/18639 0.1 5.14889502762431 0.178131641389212 0.493065596231673 GO:0003725 double-stranded RNA binding 3/362 75/18639 0.04 2.05955801104972 0.17872961253441 0.493065596231673 GO:0015144 carbohydrate transmembrane transporter activity 2/362 40/18639 0.05 2.57444751381215 0.182022801437718 0.493065596231673 GO:0032451 demethylase activity 2/362 40/18639 0.05 2.57444751381215 0.182022801437718 0.493065596231673 GO:0050997 quaternary ammonium group binding 2/362 40/18639 0.05 2.57444751381215 0.182022801437718 0.493065596231673 GO:0061791 GTPase motor activity 2/362 40/18639 0.05 2.57444751381215 0.182022801437718 0.493065596231673 GO:1990606 membrane scission GTPase motor activity 2/362 40/18639 0.05 2.57444751381215 0.182022801437718 0.493065596231673 GO:0017124 SH3 domain binding 4/362 115/18639 0.0347826086956522 1.79092000960846 0.185274598671691 0.495678586908916 GO:0017171 serine hydrolase activity 6/362 198/18639 0.0303030303030303 1.56027122049222 0.188555921769693 0.495678586908916 GO:0042287 MHC protein binding 2/362 41/18639 0.0487804878048781 2.51165611103625 0.189049326812849 0.495678586908916 GO:0061650 ubiquitin-like protein conjugating enzyme activity 2/362 41/18639 0.0487804878048781 2.51165611103625 0.189049326812849 0.495678586908916 GO:0001851 complement component C3b binding 1/362 11/18639 0.0909090909090909 4.68081366147664 0.194102243451433 0.495678586908916 GO:0008526 phosphatidylinositol transfer activity 1/362 11/18639 0.0909090909090909 4.68081366147664 0.194102243451433 0.495678586908916 GO:0015205 nucleobase transmembrane transporter activity 1/362 11/18639 0.0909090909090909 4.68081366147664 0.194102243451433 0.495678586908916 GO:0015217 ADP transmembrane transporter activity 1/362 11/18639 0.0909090909090909 4.68081366147664 0.194102243451433 0.495678586908916 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 1/362 11/18639 0.0909090909090909 4.68081366147664 0.194102243451433 0.495678586908916 GO:0031731 CCR6 chemokine receptor binding 1/362 11/18639 0.0909090909090909 4.68081366147664 0.194102243451433 0.495678586908916 GO:0034713 type I transforming growth factor beta receptor binding 1/362 11/18639 0.0909090909090909 4.68081366147664 0.194102243451433 0.495678586908916 GO:0098973 structural constituent of postsynaptic actin cytoskeleton 1/362 11/18639 0.0909090909090909 4.68081366147664 0.194102243451433 0.495678586908916 GO:0140537 transcription regulator activator activity 1/362 11/18639 0.0909090909090909 4.68081366147664 0.194102243451433 0.495678586908916 GO:0016829 lyase activity 6/362 200/18639 0.03 1.54466850828729 0.194457185259858 0.495678586908916 GO:0031492 nucleosomal DNA binding 2/362 42/18639 0.0476190476190476 2.4518547750592 0.196112103134843 0.495678586908916 GO:0035198 miRNA binding 2/362 42/18639 0.0476190476190476 2.4518547750592 0.196112103134843 0.495678586908916 GO:0048487 beta-tubulin binding 2/362 42/18639 0.0476190476190476 2.4518547750592 0.196112103134843 0.495678586908916 GO:0003924 GTPase activity 9/362 331/18639 0.027190332326284 1.40000166914256 0.196519588166895 0.495678586908916 GO:0003714 transcription corepressor activity 6/362 204/18639 0.0294117647058824 1.51438089047774 0.206464786217768 0.495678586908916 GO:0004540 RNA nuclease activity 4/362 121/18639 0.0330578512396694 1.70211405871878 0.2091147905158 0.495678586908916 GO:0004032 aldose reductase (NADPH) activity 1/362 12/18639 0.0833333333333333 4.29074585635359 0.209763344367826 0.495678586908916 GO:0004300 enoyl-CoA hydratase activity 1/362 12/18639 0.0833333333333333 4.29074585635359 0.209763344367826 0.495678586908916 GO:0004875 complement receptor activity 1/362 12/18639 0.0833333333333333 4.29074585635359 0.209763344367826 0.495678586908916 GO:0005165 neurotrophin receptor binding 1/362 12/18639 0.0833333333333333 4.29074585635359 0.209763344367826 0.495678586908916 GO:0017166 vinculin binding 1/362 12/18639 0.0833333333333333 4.29074585635359 0.209763344367826 0.495678586908916 GO:0034452 dynactin binding 1/362 12/18639 0.0833333333333333 4.29074585635359 0.209763344367826 0.495678586908916 GO:0035497 cAMP response element binding 1/362 12/18639 0.0833333333333333 4.29074585635359 0.209763344367826 0.495678586908916 GO:0043047 single-stranded telomeric DNA binding 1/362 12/18639 0.0833333333333333 4.29074585635359 0.209763344367826 0.495678586908916 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 1/362 12/18639 0.0833333333333333 4.29074585635359 0.209763344367826 0.495678586908916 GO:0070008 serine-type exopeptidase activity 1/362 12/18639 0.0833333333333333 4.29074585635359 0.209763344367826 0.495678586908916 GO:0097677 STAT family protein binding 1/362 12/18639 0.0833333333333333 4.29074585635359 0.209763344367826 0.495678586908916 GO:0140807 NAD+-protein-glutamate ADP-ribosyltransferase activity 1/362 12/18639 0.0833333333333333 4.29074585635359 0.209763344367826 0.495678586908916 GO:0140822 NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity 1/362 12/18639 0.0833333333333333 4.29074585635359 0.209763344367826 0.495678586908916 GO:0140844 NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity 1/362 12/18639 0.0833333333333333 4.29074585635359 0.209763344367826 0.495678586908916 GO:0140867 NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity 1/362 12/18639 0.0833333333333333 4.29074585635359 0.209763344367826 0.495678586908916 GO:1990247 N6-methyladenosine-containing RNA reader activity 1/362 12/18639 0.0833333333333333 4.29074585635359 0.209763344367826 0.495678586908916 GO:1990459 transferrin receptor binding 1/362 12/18639 0.0833333333333333 4.29074585635359 0.209763344367826 0.495678586908916 GO:0030547 signaling receptor inhibitor activity 2/362 44/18639 0.0454545454545455 2.34040683073832 0.210330376340417 0.495678586908916 GO:0043014 alpha-tubulin binding 2/362 44/18639 0.0454545454545455 2.34040683073832 0.210330376340417 0.495678586908916 GO:0046915 transition metal ion transmembrane transporter activity 2/362 45/18639 0.0444444444444444 2.28839779005525 0.217478209553184 0.50849998255804 GO:0004860 protein kinase inhibitor activity 3/362 84/18639 0.0357142857142857 1.8388910812944 0.223605328740433 0.50849998255804 GO:0004180 carboxypeptidase activity 2/362 46/18639 0.0434782608695652 2.23865001201057 0.224646958497213 0.50849998255804 GO:0030291 protein serine/threonine kinase inhibitor activity 2/362 46/18639 0.0434782608695652 2.23865001201057 0.224646958497213 0.50849998255804 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 1/362 13/18639 0.0769230769230769 3.96068848278793 0.225120925800094 0.50849998255804 GO:0005542 folic acid binding 1/362 13/18639 0.0769230769230769 3.96068848278793 0.225120925800094 0.50849998255804 GO:0017154 semaphorin receptor activity 1/362 13/18639 0.0769230769230769 3.96068848278793 0.225120925800094 0.50849998255804 GO:0043560 insulin receptor substrate binding 1/362 13/18639 0.0769230769230769 3.96068848278793 0.225120925800094 0.50849998255804 GO:0045028 G protein-coupled purinergic nucleotide receptor activity 1/362 13/18639 0.0769230769230769 3.96068848278793 0.225120925800094 0.50849998255804 GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity 1/362 13/18639 0.0769230769230769 3.96068848278793 0.225120925800094 0.50849998255804 GO:0071837 HMG box domain binding 1/362 13/18639 0.0769230769230769 3.96068848278793 0.225120925800094 0.50849998255804 GO:0140410 monoatomic cation:bicarbonate symporter activity 1/362 13/18639 0.0769230769230769 3.96068848278793 0.225120925800094 0.50849998255804 GO:0140806 NAD+-protein-aspartate ADP-ribosyltransferase activity 1/362 13/18639 0.0769230769230769 3.96068848278793 0.225120925800094 0.50849998255804 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 3/362 86/18639 0.0348837209302326 1.79612617242708 0.233870423528474 0.514569284429834 GO:0031490 chromatin DNA binding 4/362 128/18639 0.03125 1.6090296961326 0.237945249939471 0.514569284429834 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 2/362 48/18639 0.0416666666666667 2.1453729281768 0.239033343166251 0.514569284429834 GO:0038187 pattern recognition receptor activity 2/362 48/18639 0.0416666666666667 2.1453729281768 0.239033343166251 0.514569284429834 GO:0140693 molecular condensate scaffold activity 2/362 48/18639 0.0416666666666667 2.1453729281768 0.239033343166251 0.514569284429834 GO:0008081 phosphoric diester hydrolase activity 3/362 87/18639 0.0344827586206897 1.77548104400838 0.23903450230941 0.514569284429834 GO:0005347 ATP transmembrane transporter activity 1/362 14/18639 0.0714285714285714 3.67778216258879 0.240180854118593 0.514569284429834 GO:0016530 metallochaperone activity 1/362 14/18639 0.0714285714285714 3.67778216258879 0.240180854118593 0.514569284429834 GO:0019992 diacylglycerol binding 1/362 14/18639 0.0714285714285714 3.67778216258879 0.240180854118593 0.514569284429834 GO:0031404 chloride ion binding 1/362 14/18639 0.0714285714285714 3.67778216258879 0.240180854118593 0.514569284429834 GO:0034236 protein kinase A catalytic subunit binding 1/362 14/18639 0.0714285714285714 3.67778216258879 0.240180854118593 0.514569284429834 GO:0042043 neurexin family protein binding 1/362 14/18639 0.0714285714285714 3.67778216258879 0.240180854118593 0.514569284429834 GO:0043176 amine binding 1/362 14/18639 0.0714285714285714 3.67778216258879 0.240180854118593 0.514569284429834 GO:0061665 SUMO ligase activity 1/362 14/18639 0.0714285714285714 3.67778216258879 0.240180854118593 0.514569284429834 GO:0061783 peptidoglycan muralytic activity 1/362 14/18639 0.0714285714285714 3.67778216258879 0.240180854118593 0.514569284429834 GO:0098847 sequence-specific single stranded DNA binding 1/362 14/18639 0.0714285714285714 3.67778216258879 0.240180854118593 0.514569284429834 GO:1901612 cardiolipin binding 1/362 14/18639 0.0714285714285714 3.67778216258879 0.240180854118593 0.514569284429834 GO:0016763 pentosyltransferase activity 2/362 49/18639 0.0408163265306122 2.1015898071936 0.246244363151585 0.524609056239902 GO:0016298 lipase activity 4/362 130/18639 0.0307692307692308 1.58427539311517 0.246351070256927 0.524609056239902 GO:0019210 kinase inhibitor activity 3/362 90/18639 0.0333333333333333 1.71629834254144 0.254636815242769 0.530143705915338 GO:0005041 low-density lipoprotein particle receptor activity 1/362 15/18639 0.0666666666666667 3.43259668508287 0.254948882618409 0.530143705915338 GO:0005523 tropomyosin binding 1/362 15/18639 0.0666666666666667 3.43259668508287 0.254948882618409 0.530143705915338 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 1/362 15/18639 0.0666666666666667 3.43259668508287 0.254948882618409 0.530143705915338 GO:0048531 beta-1,3-galactosyltransferase activity 1/362 15/18639 0.0666666666666667 3.43259668508287 0.254948882618409 0.530143705915338 GO:0055105 ubiquitin-protein transferase inhibitor activity 1/362 15/18639 0.0666666666666667 3.43259668508287 0.254948882618409 0.530143705915338 GO:0061578 K63-linked deubiquitinase activity 1/362 15/18639 0.0666666666666667 3.43259668508287 0.254948882618409 0.530143705915338 GO:0120283 protein serine/threonine kinase binding 1/362 15/18639 0.0666666666666667 3.43259668508287 0.254948882618409 0.530143705915338 GO:0004252 serine-type endopeptidase activity 5/362 176/18639 0.0284090909090909 1.46275426921145 0.257593674242918 0.534072515219187 GO:0003743 translation initiation factor activity 2/362 51/18639 0.0392156862745098 2.01917452063698 0.260686425314913 0.537333244016454 GO:0005048 signal sequence binding 2/362 51/18639 0.0392156862745098 2.01917452063698 0.260686425314913 0.537333244016454 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 7/362 268/18639 0.0261194029850746 1.34486064154366 0.266265184209045 0.538100203844382 GO:0003688 DNA replication origin binding 1/362 16/18639 0.0625 3.21805939226519 0.269430653692944 0.538100203844382 GO:0005149 interleukin-1 receptor binding 1/362 16/18639 0.0625 3.21805939226519 0.269430653692944 0.538100203844382 GO:0005521 lamin binding 1/362 16/18639 0.0625 3.21805939226519 0.269430653692944 0.538100203844382 GO:0008142 oxysterol binding 1/362 16/18639 0.0625 3.21805939226519 0.269430653692944 0.538100203844382 GO:0008296 3'-5'-DNA exonuclease activity 1/362 16/18639 0.0625 3.21805939226519 0.269430653692944 0.538100203844382 GO:0016722 oxidoreductase activity, acting on metal ions 1/362 16/18639 0.0625 3.21805939226519 0.269430653692944 0.538100203844382 GO:0019841 retinol binding 1/362 16/18639 0.0625 3.21805939226519 0.269430653692944 0.538100203844382 GO:0022858 alanine transmembrane transporter activity 1/362 16/18639 0.0625 3.21805939226519 0.269430653692944 0.538100203844382 GO:0031435 mitogen-activated protein kinase kinase kinase binding 1/362 16/18639 0.0625 3.21805939226519 0.269430653692944 0.538100203844382 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 1/362 16/18639 0.0625 3.21805939226519 0.269430653692944 0.538100203844382 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 1/362 17/18639 0.0588235294117647 3.02876178095548 0.28363170096584 0.55241766551749 GO:0005092 GDP-dissociation inhibitor activity 1/362 17/18639 0.0588235294117647 3.02876178095548 0.28363170096584 0.55241766551749 GO:0016018 cyclosporin A binding 1/362 17/18639 0.0588235294117647 3.02876178095548 0.28363170096584 0.55241766551749 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 1/362 17/18639 0.0588235294117647 3.02876178095548 0.28363170096584 0.55241766551749 GO:0031489 myosin V binding 1/362 17/18639 0.0588235294117647 3.02876178095548 0.28363170096584 0.55241766551749 GO:0032977 membrane insertase activity 1/362 17/18639 0.0588235294117647 3.02876178095548 0.28363170096584 0.55241766551749 GO:0045125 bioactive lipid receptor activity 1/362 17/18639 0.0588235294117647 3.02876178095548 0.28363170096584 0.55241766551749 GO:0046965 nuclear retinoid X receptor binding 1/362 17/18639 0.0588235294117647 3.02876178095548 0.28363170096584 0.55241766551749 GO:0070403 NAD+ binding 1/362 17/18639 0.0588235294117647 3.02876178095548 0.28363170096584 0.55241766551749 GO:0061135 endopeptidase regulator activity 5/362 184/18639 0.0271739130434783 1.39915625750661 0.287281798601663 0.557989647284 GO:0042626 ATPase-coupled transmembrane transporter activity 3/362 98/18639 0.0306122448979592 1.5761923553952 0.296825782647121 0.562919579861851 GO:0004706 JUN kinase kinase kinase activity 1/362 18/18639 0.0555555555555556 2.86049723756906 0.297557451382034 0.562919579861851 GO:0008409 5'-3' exonuclease activity 1/362 18/18639 0.0555555555555556 2.86049723756906 0.297557451382034 0.562919579861851 GO:0008525 phosphatidylcholine transporter activity 1/362 18/18639 0.0555555555555556 2.86049723756906 0.297557451382034 0.562919579861851 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 1/362 18/18639 0.0555555555555556 2.86049723756906 0.297557451382034 0.562919579861851 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 1/362 18/18639 0.0555555555555556 2.86049723756906 0.297557451382034 0.562919579861851 GO:0030228 lipoprotein particle receptor activity 1/362 18/18639 0.0555555555555556 2.86049723756906 0.297557451382034 0.562919579861851 GO:0070064 proline-rich region binding 1/362 18/18639 0.0555555555555556 2.86049723756906 0.297557451382034 0.562919579861851 GO:1990381 ubiquitin-specific protease binding 1/362 18/18639 0.0555555555555556 2.86049723756906 0.297557451382034 0.562919579861851 GO:0020037 heme binding 4/362 142/18639 0.028169014084507 1.45039296552797 0.29794309752497 0.562919579861851 GO:0008234 cysteine-type peptidase activity 5/362 187/18639 0.0267379679144385 1.37670990043431 0.298578277861661 0.562919579861851 GO:0043130 ubiquitin binding 3/362 100/18639 0.03 1.54466850828729 0.307453049405875 0.575988878722284 GO:0061980 regulatory RNA binding 2/362 58/18639 0.0344827586206897 1.77548104400838 0.311150911566708 0.575988878722284 GO:0005346 purine ribonucleotide transmembrane transporter activity 1/362 19/18639 0.0526315789473684 2.70994475138122 0.311213227258717 0.575988878722284 GO:0016918 retinal binding 1/362 19/18639 0.0526315789473684 2.70994475138122 0.311213227258717 0.575988878722284 GO:0042834 peptidoglycan binding 1/362 19/18639 0.0526315789473684 2.70994475138122 0.311213227258717 0.575988878722284 GO:0043395 heparan sulfate proteoglycan binding 1/362 19/18639 0.0526315789473684 2.70994475138122 0.311213227258717 0.575988878722284 GO:0046624 sphingolipid transporter activity 1/362 19/18639 0.0526315789473684 2.70994475138122 0.311213227258717 0.575988878722284 GO:0035091 phosphatidylinositol binding 7/362 284/18639 0.0246478873239437 1.26909384483698 0.315064392802724 0.579604407820084 GO:0004879 nuclear receptor activity 2/362 59/18639 0.0338983050847458 1.74538814495739 0.31831622968972 0.579604407820084 GO:0015459 potassium channel regulator activity 2/362 59/18639 0.0338983050847458 1.74538814495739 0.31831622968972 0.579604407820084 GO:0036002 pre-mRNA binding 2/362 59/18639 0.0338983050847458 1.74538814495739 0.31831622968972 0.579604407820084 GO:0070063 RNA polymerase binding 2/362 59/18639 0.0338983050847458 1.74538814495739 0.31831622968972 0.579604407820084 GO:0070888 E-box binding 2/362 59/18639 0.0338983050847458 1.74538814495739 0.31831622968972 0.579604407820084 GO:0001614 purinergic nucleotide receptor activity 1/362 20/18639 0.05 2.57444751381215 0.324604248296974 0.579604407820084 GO:0016004 phospholipase activator activity 1/362 20/18639 0.05 2.57444751381215 0.324604248296974 0.579604407820084 GO:0016502 nucleotide receptor activity 1/362 20/18639 0.05 2.57444751381215 0.324604248296974 0.579604407820084 GO:0016505 peptidase activator activity involved in apoptotic process 1/362 20/18639 0.05 2.57444751381215 0.324604248296974 0.579604407820084 GO:0030742 GTP-dependent protein binding 1/362 20/18639 0.05 2.57444751381215 0.324604248296974 0.579604407820084 GO:0042288 MHC class I protein binding 1/362 20/18639 0.05 2.57444751381215 0.324604248296974 0.579604407820084 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 2/362 60/18639 0.0333333333333333 1.71629834254144 0.325463861251165 0.579604407820084 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 2/362 60/18639 0.0333333333333333 1.71629834254144 0.325463861251165 0.579604407820084 GO:0098531 ligand-modulated transcription factor activity 2/362 60/18639 0.0333333333333333 1.71629834254144 0.325463861251165 0.579604407820084 GO:0016836 hydro-lyase activity 2/362 61/18639 0.0327868852459016 1.68816230413912 0.332591794068586 0.590810046247463 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 1/362 21/18639 0.0476190476190476 2.4518547750592 0.337735633554855 0.592503952663232 GO:0001846 opsonin binding 1/362 21/18639 0.0476190476190476 2.4518547750592 0.337735633554855 0.592503952663232 GO:0036122 BMP binding 1/362 21/18639 0.0476190476190476 2.4518547750592 0.337735633554855 0.592503952663232 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 1/362 21/18639 0.0476190476190476 2.4518547750592 0.337735633554855 0.592503952663232 GO:0070182 DNA polymerase binding 1/362 21/18639 0.0476190476190476 2.4518547750592 0.337735633554855 0.592503952663232 GO:0008093 cytoskeletal anchor activity 1/362 22/18639 0.0454545454545455 2.34040683073832 0.35061240338261 0.612056714053099 GO:0070034 telomerase RNA binding 1/362 22/18639 0.0454545454545455 2.34040683073832 0.35061240338261 0.612056714053099 GO:0030695 GTPase regulator activity 11/362 489/18639 0.0224948875255624 1.15823814527336 0.35282960285099 0.612912442228673 GO:0004536 DNA nuclease activity 2/362 64/18639 0.03125 1.6090296961326 0.353838529112911 0.612912442228673 GO:0060589 nucleoside-triphosphatase regulator activity 11/362 490/18639 0.0224489795918367 1.15587439395648 0.355281840587314 0.612912442228673 GO:0019843 rRNA binding 2/362 65/18639 0.0307692307692308 1.58427539311517 0.360869195749736 0.612912442228673 GO:0000295 adenine nucleotide transmembrane transporter activity 1/362 23/18639 0.0434782608695652 2.23865001201057 0.363239481320812 0.612912442228673 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 1/362 23/18639 0.0434782608695652 2.23865001201057 0.363239481320812 0.612912442228673 GO:0005158 insulin receptor binding 1/362 23/18639 0.0434782608695652 2.23865001201057 0.363239481320812 0.612912442228673 GO:0008171 O-methyltransferase activity 1/362 23/18639 0.0434782608695652 2.23865001201057 0.363239481320812 0.612912442228673 GO:0016849 phosphorus-oxygen lyase activity 1/362 23/18639 0.0434782608695652 2.23865001201057 0.363239481320812 0.612912442228673 GO:0017134 fibroblast growth factor binding 1/362 23/18639 0.0434782608695652 2.23865001201057 0.363239481320812 0.612912442228673 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 1/362 23/18639 0.0434782608695652 2.23865001201057 0.363239481320812 0.612912442228673 GO:0099186 structural constituent of postsynapse 1/362 23/18639 0.0434782608695652 2.23865001201057 0.363239481320812 0.612912442228673 GO:0140103 catalytic activity, acting on a glycoprotein 1/362 23/18639 0.0434782608695652 2.23865001201057 0.363239481320812 0.612912442228673 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 1/362 23/18639 0.0434782608695652 2.23865001201057 0.363239481320812 0.612912442228673 GO:1902936 phosphatidylinositol bisphosphate binding 3/362 111/18639 0.027027027027027 1.39159325070927 0.365928018703536 0.615978831484286 GO:0003712 transcription coregulator activity 11/362 495/18639 0.0222222222222222 1.14419889502762 0.367581063097824 0.617291714038388 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 2/362 67/18639 0.0298507462686567 1.53698359033561 0.374843358140983 0.617591951267886 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 1/362 24/18639 0.0416666666666667 2.1453729281768 0.375621695962081 0.617591951267886 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 1/362 24/18639 0.0416666666666667 2.1453729281768 0.375621695962081 0.617591951267886 GO:0030215 semaphorin receptor binding 1/362 24/18639 0.0416666666666667 2.1453729281768 0.375621695962081 0.617591951267886 GO:0030552 cAMP binding 1/362 24/18639 0.0416666666666667 2.1453729281768 0.375621695962081 0.617591951267886 GO:0035035 histone acetyltransferase binding 1/362 24/18639 0.0416666666666667 2.1453729281768 0.375621695962081 0.617591951267886 GO:0050699 WW domain binding 1/362 24/18639 0.0416666666666667 2.1453729281768 0.375621695962081 0.617591951267886 GO:0060229 lipase activator activity 1/362 24/18639 0.0416666666666667 2.1453729281768 0.375621695962081 0.617591951267886 GO:0070300 phosphatidic acid binding 1/362 24/18639 0.0416666666666667 2.1453729281768 0.375621695962081 0.617591951267886 GO:0032934 sterol binding 2/362 68/18639 0.0294117647058824 1.51438089047774 0.381783839967112 0.623909777603886 GO:0004518 nuclease activity 5/362 209/18639 0.0239234449760766 1.23179306880964 0.382862035609114 0.623909777603886 GO:0001221 transcription coregulator binding 3/362 115/18639 0.0260869565217391 1.34319000720634 0.387037318784797 0.623909777603886 GO:0001848 complement binding 1/362 25/18639 0.04 2.05955801104972 0.387763782777108 0.623909777603886 GO:0004709 MAP kinase kinase kinase activity 1/362 25/18639 0.04 2.05955801104972 0.387763782777108 0.623909777603886 GO:0005537 D-mannose binding 1/362 25/18639 0.04 2.05955801104972 0.387763782777108 0.623909777603886 GO:0008139 nuclear localization sequence binding 1/362 25/18639 0.04 2.05955801104972 0.387763782777108 0.623909777603886 GO:0042974 nuclear retinoic acid receptor binding 1/362 25/18639 0.04 2.05955801104972 0.387763782777108 0.623909777603886 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 1/362 25/18639 0.04 2.05955801104972 0.387763782777108 0.623909777603886 GO:0004175 endopeptidase activity 9/362 405/18639 0.0222222222222222 1.14419889502762 0.388288970503126 0.623909777603886 GO:1990782 protein tyrosine kinase binding 3/362 117/18639 0.0256410256410256 1.32022949426264 0.397531323892504 0.632140856454798 GO:0004112 cyclic-nucleotide phosphodiesterase activity 1/362 26/18639 0.0384615384615385 1.98034424139397 0.39967038590565 0.632140856454798 GO:0005160 transforming growth factor beta receptor binding 1/362 26/18639 0.0384615384615385 1.98034424139397 0.39967038590565 0.632140856454798 GO:0015216 purine nucleotide transmembrane transporter activity 1/362 26/18639 0.0384615384615385 1.98034424139397 0.39967038590565 0.632140856454798 GO:0034237 protein kinase A regulatory subunit binding 1/362 26/18639 0.0384615384615385 1.98034424139397 0.39967038590565 0.632140856454798 GO:0097602 cullin family protein binding 1/362 26/18639 0.0384615384615385 1.98034424139397 0.39967038590565 0.632140856454798 GO:0120014 phospholipid transfer activity 1/362 26/18639 0.0384615384615385 1.98034424139397 0.39967038590565 0.632140856454798 GO:0005044 scavenger receptor activity 1/362 27/18639 0.037037037037037 1.90699815837937 0.41134605991318 0.6405758369889 GO:0005104 fibroblast growth factor receptor binding 1/362 27/18639 0.037037037037037 1.90699815837937 0.41134605991318 0.6405758369889 GO:0005385 zinc ion transmembrane transporter activity 1/362 27/18639 0.037037037037037 1.90699815837937 0.41134605991318 0.6405758369889 GO:0008266 poly(U) RNA binding 1/362 27/18639 0.037037037037037 1.90699815837937 0.41134605991318 0.6405758369889 GO:0008320 protein transmembrane transporter activity 1/362 27/18639 0.037037037037037 1.90699815837937 0.41134605991318 0.6405758369889 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors 1/362 27/18639 0.037037037037037 1.90699815837937 0.41134605991318 0.6405758369889 GO:0035255 ionotropic glutamate receptor binding 1/362 27/18639 0.037037037037037 1.90699815837937 0.41134605991318 0.6405758369889 GO:0005201 extracellular matrix structural constituent 4/362 168/18639 0.0238095238095238 1.2259273875296 0.412251776279985 0.6405758369889 GO:0032182 ubiquitin-like protein binding 3/362 120/18639 0.025 1.28722375690608 0.413178995480683 0.640608661852726 GO:0004521 RNA endonuclease activity 2/362 73/18639 0.0273972602739726 1.41065617195187 0.415966040525326 0.643115044388396 GO:0030414 peptidase inhibitor activity 4/362 169/18639 0.0236686390532544 1.21867337931936 0.416614837807476 0.643115044388396 GO:0003697 single-stranded DNA binding 3/362 121/18639 0.0247933884297521 1.27658554403908 0.418367068488265 0.643963069307658 GO:0031491 nucleosome binding 2/362 74/18639 0.027027027027027 1.39159325070927 0.422689948628363 0.643963069307658 GO:0019789 SUMO transferase activity 1/362 28/18639 0.0357142857142857 1.8388910812944 0.422795271513837 0.643963069307658 GO:0051019 mitogen-activated protein kinase binding 1/362 28/18639 0.0357142857142857 1.8388910812944 0.422795271513837 0.643963069307658 GO:0051537 2 iron, 2 sulfur cluster binding 1/362 28/18639 0.0357142857142857 1.8388910812944 0.422795271513837 0.643963069307658 GO:0051959 dynein light intermediate chain binding 1/362 28/18639 0.0357142857142857 1.8388910812944 0.422795271513837 0.643963069307658 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 3/362 122/18639 0.0245901639344262 1.26612172810434 0.423540066800652 0.643963069307658 GO:0019003 GDP binding 2/362 75/18639 0.0266666666666667 1.37303867403315 0.429373793452855 0.65143191410122 GO:0004181 metallocarboxypeptidase activity 1/362 29/18639 0.0344827586206897 1.77548104400838 0.43402240126033 0.654272575034229 GO:0004629 phospholipase C activity 1/362 29/18639 0.0344827586206897 1.77548104400838 0.43402240126033 0.654272575034229 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 1/362 29/18639 0.0344827586206897 1.77548104400838 0.43402240126033 0.654272575034229 GO:0017022 myosin binding 2/362 76/18639 0.0263157894736842 1.35497237569061 0.436016593334986 0.655880279761351 GO:0008106 alcohol dehydrogenase (NADP+) activity 1/362 30/18639 0.0333333333333333 1.71629834254144 0.445031745201424 0.662394618647173 GO:0008187 poly-pyrimidine tract binding 1/362 30/18639 0.0333333333333333 1.71629834254144 0.445031745201424 0.662394618647173 GO:0015215 nucleotide transmembrane transporter activity 1/362 30/18639 0.0333333333333333 1.71629834254144 0.445031745201424 0.662394618647173 GO:0016769 transferase activity, transferring nitrogenous groups 1/362 30/18639 0.0333333333333333 1.71629834254144 0.445031745201424 0.662394618647173 GO:0098918 structural constituent of synapse 1/362 30/18639 0.0333333333333333 1.71629834254144 0.445031745201424 0.662394618647173 GO:0008017 microtubule binding 6/362 276/18639 0.0217391304347826 1.11932500600528 0.448063932004008 0.665506722535364 GO:0004519 endonuclease activity 3/362 127/18639 0.0236220472440945 1.21627441597425 0.449156038952573 0.665730229642493 GO:0016835 carbon-oxygen lyase activity 2/362 79/18639 0.0253164556962025 1.30351772851248 0.455689691593427 0.671395946189356 GO:0005164 tumor necrosis factor receptor binding 1/362 31/18639 0.032258064516129 1.66093387987881 0.455827516507625 0.671395946189356 GO:0047499 calcium-independent phospholipase A2 activity 1/362 31/18639 0.032258064516129 1.66093387987881 0.455827516507625 0.671395946189356 GO:0000287 magnesium ion binding 5/362 230/18639 0.0217391304347826 1.11932500600528 0.463022214811645 0.67711414758816 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 3/362 130/18639 0.0230769230769231 1.18820654483638 0.464304442129967 0.67711414758816 GO:0008378 galactosyltransferase activity 1/362 32/18639 0.03125 1.6090296961326 0.466413847065677 0.67711414758816 GO:0015106 bicarbonate transmembrane transporter activity 1/362 32/18639 0.03125 1.6090296961326 0.466413847065677 0.67711414758816 GO:0022884 macromolecule transmembrane transporter activity 1/362 32/18639 0.03125 1.6090296961326 0.466413847065677 0.67711414758816 GO:0043425 bHLH transcription factor binding 1/362 32/18639 0.03125 1.6090296961326 0.466413847065677 0.67711414758816 GO:0051059 NF-kappaB binding 1/362 32/18639 0.03125 1.6090296961326 0.466413847065677 0.67711414758816 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 4/362 181/18639 0.0220994475138122 1.13787735417112 0.468281936001031 0.677482644914431 GO:0030971 receptor tyrosine kinase binding 2/362 81/18639 0.0246913580246914 1.27133210558625 0.468584177317054 0.677482644914431 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 1/362 33/18639 0.0303030303030303 1.56027122049222 0.476794789042472 0.683760478403708 GO:0019239 deaminase activity 1/362 33/18639 0.0303030303030303 1.56027122049222 0.476794789042472 0.683760478403708 GO:0030296 protein tyrosine kinase activator activity 1/362 33/18639 0.0303030303030303 1.56027122049222 0.476794789042472 0.683760478403708 GO:0071889 14-3-3 protein binding 1/362 33/18639 0.0303030303030303 1.56027122049222 0.476794789042472 0.683760478403708 GO:0008135 translation factor activity, RNA binding 2/362 83/18639 0.0240963855421687 1.24069759701791 0.481295189779841 0.688817204806371 GO:0030332 cyclin binding 1/362 34/18639 0.0294117647058824 1.51438089047774 0.486974316418944 0.692207385537423 GO:0004527 exonuclease activity 2/362 84/18639 0.0238095238095238 1.2259273875296 0.487580308341777 0.692207385537423 GO:0051117 ATPase binding 2/362 84/18639 0.0238095238095238 1.2259273875296 0.487580308341777 0.692207385537423 GO:0180051 translation factor activity 2/362 84/18639 0.0238095238095238 1.2259273875296 0.487580308341777 0.692207385537423 GO:0000175 3'-5'-RNA exonuclease activity 1/362 35/18639 0.0285714285714286 1.47111286503552 0.496956326494533 0.699743088756816 GO:0004623 phospholipase A2 activity 1/362 35/18639 0.0285714285714286 1.47111286503552 0.496956326494533 0.699743088756816 GO:0061631 ubiquitin conjugating enzyme activity 1/362 35/18639 0.0285714285714286 1.47111286503552 0.496956326494533 0.699743088756816 GO:0140597 protein carrier chaperone 4/362 188/18639 0.0212765957446809 1.0955095803456 0.497655887596219 0.699743088756816 GO:0004033 aldo-keto reductase (NADPH) activity 1/362 36/18639 0.0277777777777778 1.43024861878453 0.506744641362786 0.699743088756816 GO:0004869 cysteine-type endopeptidase inhibitor activity 1/362 36/18639 0.0277777777777778 1.43024861878453 0.506744641362786 0.699743088756816 GO:0005484 SNAP receptor activity 1/362 36/18639 0.0277777777777778 1.43024861878453 0.506744641362786 0.699743088756816 GO:0016409 palmitoyltransferase activity 1/362 36/18639 0.0277777777777778 1.43024861878453 0.506744641362786 0.699743088756816 GO:0044390 ubiquitin-like protein conjugating enzyme binding 1/362 36/18639 0.0277777777777778 1.43024861878453 0.506744641362786 0.699743088756816 GO:0045505 dynein intermediate chain binding 1/362 36/18639 0.0277777777777778 1.43024861878453 0.506744641362786 0.699743088756816 GO:0055106 ubiquitin-protein transferase regulator activity 1/362 36/18639 0.0277777777777778 1.43024861878453 0.506744641362786 0.699743088756816 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 1/362 36/18639 0.0277777777777778 1.43024861878453 0.506744641362786 0.699743088756816 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 1/362 36/18639 0.0277777777777778 1.43024861878453 0.506744641362786 0.699743088756816 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 1/362 36/18639 0.0277777777777778 1.43024861878453 0.506744641362786 0.699743088756816 GO:0140767 enzyme-substrate adaptor activity 3/362 139/18639 0.0215827338129496 1.11127230812035 0.508590922145577 0.700923551572949 GO:0019213 deacetylase activity 1/362 37/18639 0.027027027027027 1.39159325070927 0.516343009358629 0.707469976001068 GO:0030280 structural constituent of skin epidermis 1/362 37/18639 0.027027027027027 1.39159325070927 0.516343009358629 0.707469976001068 GO:0030551 cyclic nucleotide binding 1/362 37/18639 0.027027027027027 1.39159325070927 0.516343009358629 0.707469976001068 GO:0003727 single-stranded RNA binding 2/362 89/18639 0.0224719101123595 1.15705506238749 0.518280713729242 0.708751382217745 GO:0005109 frizzled binding 1/362 38/18639 0.0263157894736842 1.35497237569061 0.525755106477873 0.712085939233442 GO:0005501 retinoid binding 1/362 38/18639 0.0263157894736842 1.35497237569061 0.525755106477873 0.712085939233442 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 1/362 38/18639 0.0263157894736842 1.35497237569061 0.525755106477873 0.712085939233442 GO:0019840 isoprenoid binding 1/362 38/18639 0.0263157894736842 1.35497237569061 0.525755106477873 0.712085939233442 GO:0042162 telomeric DNA binding 1/362 38/18639 0.0263157894736842 1.35497237569061 0.525755106477873 0.712085939233442 GO:0140104 molecular carrier activity 5/362 249/18639 0.0200803212851406 1.03391466418159 0.532760663836056 0.72019462587398 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 1/362 39/18639 0.0256410256410256 1.32022949426264 0.534984537769471 0.72058260296379 GO:0043178 alcohol binding 2/362 92/18639 0.0217391304347826 1.11932500600528 0.53610530291224 0.72058260296379 GO:0052689 carboxylic ester hydrolase activity 2/362 92/18639 0.0217391304347826 1.11932500600528 0.53610530291224 0.72058260296379 GO:0004532 RNA exonuclease activity 1/362 40/18639 0.025 1.28722375690608 0.544034838701055 0.727093820343375 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 1/362 40/18639 0.025 1.28722375690608 0.544034838701055 0.727093820343375 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 1/362 40/18639 0.025 1.28722375690608 0.544034838701055 0.727093820343375 GO:0015175 neutral L-amino acid transmembrane transporter activity 1/362 41/18639 0.024390243902439 1.25582805551812 0.55290947649826 0.734787593767424 GO:0017080 sodium channel regulator activity 1/362 41/18639 0.024390243902439 1.25582805551812 0.55290947649826 0.734787593767424 GO:0140318 protein transporter activity 1/362 41/18639 0.024390243902439 1.25582805551812 0.55290947649826 0.734787593767424 GO:0016407 acetyltransferase activity 2/362 96/18639 0.0208333333333333 1.0726864640884 0.559158471919267 0.740782796606434 GO:0019842 vitamin binding 3/362 150/18639 0.02 1.02977900552486 0.560000690512299 0.740782796606434 GO:0016859 cis-trans isomerase activity 1/362 42/18639 0.0238095238095238 1.2259273875296 0.561611851458343 0.740782796606434 GO:0019894 kinesin binding 1/362 42/18639 0.0238095238095238 1.2259273875296 0.561611851458343 0.740782796606434 GO:0016887 ATP hydrolysis activity 8/362 417/18639 0.0191846522781775 0.987797607218093 0.563935424125783 0.742462467145118 GO:0004712 protein serine/threonine/tyrosine kinase activity 1/362 43/18639 0.0232558139534884 1.19741744828472 0.570145298238581 0.749242984859994 GO:0005506 iron ion binding 3/362 154/18639 0.0194805194805195 1.00303149888785 0.577875159548344 0.753238955053025 GO:0003730 mRNA 3'-UTR binding 5/362 262/18639 0.0190839694656489 0.982613554890135 0.578048862954995 0.753238955053025 GO:0001046 core promoter sequence-specific DNA binding 1/362 44/18639 0.0227272727272727 1.17020341536916 0.578513087119933 0.753238955053025 GO:0016790 thiolester hydrolase activity 1/362 44/18639 0.0227272727272727 1.17020341536916 0.578513087119933 0.753238955053025 GO:0030020 extracellular matrix structural constituent conferring tensile strength 1/362 44/18639 0.0227272727272727 1.17020341536916 0.578513087119933 0.753238955053025 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 1/362 46/18639 0.0217391304347826 1.11932500600528 0.594764457840878 0.771556828795414 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 1/362 46/18639 0.0217391304347826 1.11932500600528 0.594764457840878 0.771556828795414 GO:0008514 organic anion transmembrane transporter activity 5/362 269/18639 0.0185873605947955 0.957043685432028 0.601452020584214 0.778803257423149 GO:0004866 endopeptidase inhibitor activity 3/362 161/18639 0.0186335403726708 0.959421433718815 0.608038544312674 0.784458486914344 GO:0005178 integrin binding 3/362 161/18639 0.0186335403726708 0.959421433718815 0.608038544312674 0.784458486914344 GO:0001222 transcription corepressor binding 1/362 49/18639 0.0204081632653061 1.0507949035968 0.617977270717331 0.794381691631188 GO:0035254 glutamate receptor binding 1/362 49/18639 0.0204081632653061 1.0507949035968 0.617977270717331 0.794381691631188 GO:0005496 steroid binding 2/362 108/18639 0.0185185185185185 0.953499079189687 0.623336279020144 0.799582910884569 GO:0015605 organophosphate ester transmembrane transporter activity 1/362 50/18639 0.02 1.02977900552486 0.625416336236445 0.799582910884569 GO:0032813 tumor necrosis factor receptor superfamily binding 1/362 50/18639 0.02 1.02977900552486 0.625416336236445 0.799582910884569 GO:0004222 metalloendopeptidase activity 2/362 110/18639 0.0181818181818182 0.936162732295329 0.63330351201939 0.808205023461568 GO:0005080 protein kinase C binding 1/362 52/18639 0.0192307692307692 0.990172120696983 0.639863863319053 0.812179086834059 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 1/362 52/18639 0.0192307692307692 0.990172120696983 0.639863863319053 0.812179086834059 GO:0030159 signaling receptor complex adaptor activity 1/362 52/18639 0.0192307692307692 0.990172120696983 0.639863863319053 0.812179086834059 GO:0005544 calcium-dependent phospholipid binding 1/362 53/18639 0.0188679245283019 0.971489627853643 0.646877866734263 0.815227543281861 GO:0051018 protein kinase A binding 1/362 53/18639 0.0188679245283019 0.971489627853643 0.646877866734263 0.815227543281861 GO:0140296 general transcription initiation factor binding 1/362 53/18639 0.0188679245283019 0.971489627853643 0.646877866734263 0.815227543281861 GO:1901505 carbohydrate derivative transmembrane transporter activity 1/362 53/18639 0.0188679245283019 0.971489627853643 0.646877866734263 0.815227543281861 GO:0015485 cholesterol binding 1/362 54/18639 0.0185185185185185 0.953499079189687 0.653755635605575 0.819512826902733 GO:0017069 snRNA binding 1/362 54/18639 0.0185185185185185 0.953499079189687 0.653755635605575 0.819512826902733 GO:0051287 NAD binding 1/362 54/18639 0.0185185185185185 0.953499079189687 0.653755635605575 0.819512826902733 GO:0015932 nucleobase-containing compound transmembrane transporter activity 1/362 57/18639 0.0175438596491228 0.903314917127072 0.673597670306318 0.84289124408242 GO:0005319 lipid transporter activity 3/362 178/18639 0.0168539325842697 0.867791296790614 0.6751368134363 0.843324606182799 GO:0008408 3'-5' exonuclease activity 1/362 58/18639 0.0172413793103448 0.887740522004191 0.679956385371925 0.847846850895858 GO:0031593 polyubiquitin modification-dependent protein binding 1/362 59/18639 0.0169491525423729 0.872694072478697 0.686191560469894 0.854115199387703 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 2/362 122/18639 0.0163934426229508 0.844081152069559 0.688809025353251 0.855866398813267 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 1/362 60/18639 0.0166666666666667 0.858149171270718 0.692305589270212 0.858701844936912 GO:0008237 metallopeptidase activity 3/362 184/18639 0.016304347826087 0.839493754503963 0.696702365971143 0.862641983785635 GO:0019905 syntaxin binding 1/362 61/18639 0.0163934426229508 0.844081152069559 0.698300819190239 0.863109578964159 GO:1901981 phosphatidylinositol phosphate binding 3/362 185/18639 0.0162162162162162 0.834955950425564 0.700189528783386 0.863933676875835 GO:0015179 L-amino acid transmembrane transporter activity 1/362 62/18639 0.0161290322580645 0.830466939939405 0.704179552286004 0.867343107083981 GO:0005507 copper ion binding 1/362 63/18639 0.0158730158730159 0.817284925019732 0.70994404612637 0.872922505411032 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 2/362 128/18639 0.015625 0.804514848066298 0.713875349210171 0.876232416478456 GO:0035591 signaling adaptor activity 2/362 129/18639 0.0155038759689922 0.798278298856482 0.717884807482254 0.879626618526783 GO:0160215 deacylase activity 1/362 65/18639 0.0153846153846154 0.792137696557586 0.721139129008216 0.882085405205551 GO:0008235 metalloexopeptidase activity 1/362 66/18639 0.0151515151515152 0.780135610246108 0.726574018385788 0.887198326422715 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 2/362 132/18639 0.0151515151515152 0.780135610246108 0.729630868192689 0.889394868641778 GO:0051020 GTPase binding 5/362 315/18639 0.0158730158730159 0.817284925019732 0.735387168332234 0.893911074288538 GO:0005548 phospholipid transporter activity 1/362 68/18639 0.0147058823529412 0.757190445238869 0.737128933960704 0.893911074288538 GO:0030145 manganese ion binding 1/362 68/18639 0.0147058823529412 0.757190445238869 0.737128933960704 0.893911074288538 GO:0015297 antiporter activity 2/362 135/18639 0.0148148148148148 0.76279926335175 0.740960295849915 0.895516863906748 GO:0002039 p53 binding 1/362 69/18639 0.0144927536231884 0.74621667067019 0.742253015911392 0.895516863906748 GO:0008080 N-acetyltransferase activity 1/362 69/18639 0.0144927536231884 0.74621667067019 0.742253015911392 0.895516863906748 GO:0140299 molecular sensor activity 1/362 71/18639 0.0140845070422535 0.725196482763987 0.752204275207181 0.905976869798087 GO:0016757 glycosyltransferase activity 4/362 267/18639 0.0149812734082397 0.771370041591657 0.764889570819188 0.919305883858557 GO:0140098 catalytic activity, acting on RNA 6/362 387/18639 0.0155038759689922 0.798278298856482 0.765871521347511 0.919305883858557 GO:0005516 calmodulin binding 3/362 207/18639 0.0144927536231884 0.74621667067019 0.769348421982054 0.921690496176637 GO:0051536 iron-sulfur cluster binding 1/362 76/18639 0.0131578947368421 0.677486187845304 0.775438028435127 0.921690496176637 GO:0003724 RNA helicase activity 1/362 77/18639 0.012987012987013 0.668687665925235 0.779817246972351 0.921690496176637 GO:0051540 metal cluster binding 1/362 77/18639 0.012987012987013 0.668687665925235 0.779817246972351 0.921690496176637 GO:0008186 ATP-dependent activity, acting on RNA 1/362 79/18639 0.0126582278481013 0.651758864256242 0.788321830401709 0.921690496176637 GO:0000049 tRNA binding 1/362 80/18639 0.0125 0.643611878453039 0.792450467114779 0.921690496176637 GO:0000510 H3-H4 histone complex chaperone activity 2/362 151/18639 0.0132450331125828 0.681972851340968 0.794736065589525 0.921690496176637 GO:0140584 chromatin extrusion motor activity 2/362 151/18639 0.0132450331125828 0.681972851340968 0.794736065589525 0.921690496176637 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 2/362 151/18639 0.0132450331125828 0.681972851340968 0.794736065589525 0.921690496176637 GO:0140849 ATP-dependent H2AZ histone chaperone activity 2/362 151/18639 0.0132450331125828 0.681972851340968 0.794736065589525 0.921690496176637 GO:0015101 organic cation transmembrane transporter activity 1/362 81/18639 0.0123456790123457 0.635666052793124 0.796498795737251 0.921690496176637 GO:0033192 calmodulin-dependent protein phosphatase activity 1/362 81/18639 0.0123456790123457 0.635666052793124 0.796498795737251 0.921690496176637 GO:0140791 histone H2AXS140 phosphatase activity 1/362 81/18639 0.0123456790123457 0.635666052793124 0.796498795737251 0.921690496176637 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 1/362 81/18639 0.0123456790123457 0.635666052793124 0.796498795737251 0.921690496176637 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 1/362 81/18639 0.0123456790123457 0.635666052793124 0.796498795737251 0.921690496176637 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 1/362 81/18639 0.0123456790123457 0.635666052793124 0.796498795737251 0.921690496176637 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 1/362 81/18639 0.0123456790123457 0.635666052793124 0.796498795737251 0.921690496176637 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 1/362 81/18639 0.0123456790123457 0.635666052793124 0.796498795737251 0.921690496176637 GO:1990439 MAP kinase serine/threonine phosphatase activity 1/362 81/18639 0.0123456790123457 0.635666052793124 0.796498795737251 0.921690496176637 GO:0015616 DNA translocase activity 2/362 152/18639 0.0131578947368421 0.677486187845304 0.797745949069747 0.921690496176637 GO:0140674 ATP-dependent histone chaperone activity 2/362 152/18639 0.0131578947368421 0.677486187845304 0.797745949069747 0.921690496176637 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 1/362 82/18639 0.0121951219512195 0.627914027759062 0.800468374137031 0.921690496176637 GO:0033549 MAP kinase phosphatase activity 1/362 82/18639 0.0121951219512195 0.627914027759062 0.800468374137031 0.921690496176637 GO:0003774 cytoskeletal motor activity 2/362 153/18639 0.0130718954248366 0.673058173545661 0.800716765502626 0.921690496176637 GO:0061775 cohesin loader activity 2/362 153/18639 0.0130718954248366 0.673058173545661 0.800716765502626 0.921690496176637 GO:0031267 small GTPase binding 4/362 283/18639 0.0141342756183746 0.727759014505203 0.802810686160039 0.921690496176637 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 1/362 83/18639 0.0120481927710843 0.620348798508953 0.804360730043826 0.921690496176637 GO:0005254 chloride channel activity 1/362 83/18639 0.0120481927710843 0.620348798508953 0.804360730043826 0.921690496176637 GO:0017018 myosin phosphatase activity 1/362 84/18639 0.0119047619047619 0.612963693764799 0.808177361630597 0.924565363548272 GO:0140658 ATP-dependent chromatin remodeler activity 2/362 158/18639 0.0126582278481013 0.651758864256242 0.814998038821983 0.930862057265173 GO:0003689 DNA clamp loader activity 2/362 160/18639 0.0125 0.643611878453039 0.820450270481504 0.935577969726489 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 3/362 229/18639 0.0131004366812227 0.674527732876547 0.824944400902574 0.936066972113947 GO:0019787 ubiquitin-like protein transferase activity 7/362 479/18639 0.0146137787056367 0.75244812512255 0.825596813018102 0.936066972113947 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 1/362 89/18639 0.0112359550561798 0.578527531193743 0.826175092785153 0.936066972113947 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 1/362 89/18639 0.0112359550561798 0.578527531193743 0.826175092785153 0.936066972113947 GO:0140793 histone H2AXY142 phosphatase activity 1/362 90/18639 0.0111111111111111 0.572099447513812 0.829567255394952 0.938406479302769 GO:0140713 histone chaperone activity 2/362 164/18639 0.0121951219512195 0.627914027759062 0.830925060079723 0.938440922486205 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 1/362 91/18639 0.010989010989011 0.565812640398276 0.832893399852714 0.939163690105054 GO:0016410 N-acyltransferase activity 1/362 94/18639 0.0106382978723404 0.547754790172799 0.842488414311345 0.948470237130765 GO:0004867 serine-type endopeptidase inhibitor activity 1/362 95/18639 0.0105263157894737 0.541988950276243 0.845563054053555 0.948909649548989 GO:0008276 protein methyltransferase activity 1/362 95/18639 0.0105263157894737 0.541988950276243 0.845563054053555 0.948909649548989 GO:0016755 aminoacyltransferase activity 7/362 496/18639 0.0141129032258065 0.726658572446979 0.851089581865068 0.952903717153525 GO:0061659 ubiquitin-like protein ligase activity 5/362 372/18639 0.0134408602150538 0.692055783282837 0.851817749987309 0.952903717153525 GO:0004725 protein tyrosine phosphatase activity 1/362 98/18639 0.0102040816326531 0.525397451798399 0.854432470932815 0.95431873135782 GO:0005525 GTP binding 5/362 378/18639 0.0132275132275132 0.681070770849776 0.861154480319505 0.960309491460395 GO:0015171 amino acid transmembrane transporter activity 1/362 102/18639 0.00980392156862745 0.504793630159246 0.865473124908623 0.963495864562314 GO:0004722 protein serine/threonine phosphatase activity 1/362 103/18639 0.00970873786407767 0.499892721128574 0.868100234407629 0.963495864562314 GO:0005253 monoatomic anion channel activity 1/362 103/18639 0.00970873786407767 0.499892721128574 0.868100234407629 0.963495864562314 GO:0000149 SNARE binding 1/362 106/18639 0.00943396226415094 0.485744813926822 0.875678531235955 0.968864979004414 GO:0004497 monooxygenase activity 1/362 106/18639 0.00943396226415094 0.485744813926822 0.875678531235955 0.968864979004414 GO:0004843 cysteine-type deubiquitinase activity 1/362 108/18639 0.00925925925925926 0.476749539594843 0.880487901892851 0.972663979122259 GO:0019001 guanyl nucleotide binding 5/362 400/18639 0.0125 0.643611878453039 0.891277947793229 0.98028990657456 GO:0032561 guanyl ribonucleotide binding 5/362 400/18639 0.0125 0.643611878453039 0.891277947793229 0.98028990657456 GO:0140097 catalytic activity, acting on DNA 4/362 336/18639 0.0119047619047619 0.612963693764799 0.894382524588312 0.98028990657456 GO:0101005 deubiquitinase activity 1/362 115/18639 0.00869565217391304 0.447730002402114 0.895905629138459 0.98028990657456 GO:0015294 solute:monoatomic cation symporter activity 1/362 116/18639 0.00862068965517241 0.443870261002096 0.89793986376661 0.98028990657456 GO:0016758 hexosyltransferase activity 2/362 197/18639 0.0101522842639594 0.52273045965729 0.898344416963569 0.98028990657456 GO:0015108 chloride transmembrane transporter activity 1/362 121/18639 0.00826446280991736 0.425528514679695 0.907531539337155 0.98028990657456 GO:0008168 methyltransferase activity 2/362 204/18639 0.00980392156862745 0.504793630159246 0.908981726072727 0.98028990657456 GO:0008528 G protein-coupled peptide receptor activity 1/362 122/18639 0.00819672131147541 0.422040576034779 0.909339163419667 0.98028990657456 GO:0008094 ATP-dependent activity, acting on DNA 2/362 210/18639 0.00952380952380952 0.490370955011839 0.917262360983815 0.98028990657456 GO:0019783 ubiquitin-like protein peptidase activity 1/362 127/18639 0.0078740157480315 0.405424805324749 0.917862178838487 0.98028990657456 GO:0001653 peptide receptor activity 1/362 128/18639 0.0078125 0.402257424033149 0.919468374347371 0.98028990657456 GO:0015291 secondary active transmembrane transporter activity 3/362 287/18639 0.0104529616724739 0.538212023793482 0.919748040657713 0.98028990657456 GO:0016798 hydrolase activity, acting on glycosyl bonds 1/362 130/18639 0.00769230769230769 0.396068848278793 0.922587402903603 0.98028990657456 GO:0016741 transferase activity, transferring one-carbon groups 2/362 215/18639 0.00930232558139535 0.478966979313889 0.923617715660774 0.98028990657456 GO:0005262 calcium channel activity 1/362 131/18639 0.00763358778625954 0.393045421956054 0.924101442568031 0.98028990657456 GO:0042578 phosphoric ester hydrolase activity 4/362 363/18639 0.0110192837465565 0.56737135290626 0.92478013751276 0.98028990657456 GO:0016779 nucleotidyltransferase activity 1/362 136/18639 0.00735294117647059 0.378595222619435 0.931239992055192 0.98028990657456 GO:0140789 histone phosphatase activity 1/362 136/18639 0.00735294117647059 0.378595222619435 0.931239992055192 0.98028990657456 GO:0004842 ubiquitin-protein transferase activity 5/362 449/18639 0.0111358574610245 0.573373611094021 0.938846310175357 0.98028990657456 GO:0005085 guanyl-nucleotide exchange factor activity 2/362 230/18639 0.00869565217391304 0.447730002402114 0.940036173231395 0.98028990657456 GO:0015293 symporter activity 1/362 146/18639 0.00684931506849315 0.352664042987966 0.943570580940432 0.98028990657456 GO:0015085 calcium ion transmembrane transporter activity 1/362 147/18639 0.00680272108843537 0.350264967865599 0.944675185369111 0.98028990657456 GO:0008509 monoatomic anion transmembrane transporter activity 1/362 149/18639 0.00671140939597315 0.345563424672772 0.946820121939935 0.98028990657456 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 2/362 243/18639 0.00823045267489712 0.42377736852875 0.951504187766356 0.98028990657456 GO:0004386 helicase activity 1/362 155/18639 0.00645161290322581 0.332186775975762 0.952769973594328 0.98028990657456 GO:0004676 3-phosphoinositide-dependent protein kinase activity 2/362 245/18639 0.00816326530612245 0.420317961438719 0.953071430188882 0.98028990657456 GO:0004711 ribosomal protein S6 kinase activity 2/362 245/18639 0.00816326530612245 0.420317961438719 0.953071430188882 0.98028990657456 GO:0035175 histone H3S10 kinase activity 2/362 245/18639 0.00816326530612245 0.420317961438719 0.953071430188882 0.98028990657456 GO:0035979 histone H2AXS139 kinase activity 2/362 245/18639 0.00816326530612245 0.420317961438719 0.953071430188882 0.98028990657456 GO:0044022 histone H3S28 kinase activity 2/362 245/18639 0.00816326530612245 0.420317961438719 0.953071430188882 0.98028990657456 GO:0044023 histone H4S1 kinase activity 2/362 245/18639 0.00816326530612245 0.420317961438719 0.953071430188882 0.98028990657456 GO:0044024 histone H2AS1 kinase activity 2/362 245/18639 0.00816326530612245 0.420317961438719 0.953071430188882 0.98028990657456 GO:0044025 histone H2BS14 kinase activity 2/362 245/18639 0.00816326530612245 0.420317961438719 0.953071430188882 0.98028990657456 GO:0072354 histone H3T3 kinase activity 2/362 245/18639 0.00816326530612245 0.420317961438719 0.953071430188882 0.98028990657456 GO:0072371 histone H2AS121 kinase activity 2/362 245/18639 0.00816326530612245 0.420317961438719 0.953071430188882 0.98028990657456 GO:0072518 Rho-dependent protein serine/threonine kinase activity 2/362 245/18639 0.00816326530612245 0.420317961438719 0.953071430188882 0.98028990657456 GO:0140823 histone H2BS36 kinase activity 2/362 245/18639 0.00816326530612245 0.420317961438719 0.953071430188882 0.98028990657456 GO:0140855 histone H3S57 kinase activity 2/362 245/18639 0.00816326530612245 0.420317961438719 0.953071430188882 0.98028990657456 GO:0140995 histone H2A kinase activity 2/362 245/18639 0.00816326530612245 0.420317961438719 0.953071430188882 0.98028990657456 GO:0140997 histone H4 kinase activity 2/362 245/18639 0.00816326530612245 0.420317961438719 0.953071430188882 0.98028990657456 GO:0140998 histone H2B kinase activity 2/362 245/18639 0.00816326530612245 0.420317961438719 0.953071430188882 0.98028990657456 GO:1990244 histone H2AT120 kinase activity 2/362 245/18639 0.00816326530612245 0.420317961438719 0.953071430188882 0.98028990657456 GO:0004677 DNA-dependent protein kinase activity 2/362 246/18639 0.00813008130081301 0.418609351839375 0.953836824039633 0.98028990657456 GO:0140857 histone H3T45 kinase activity 2/362 246/18639 0.00813008130081301 0.418609351839375 0.953836824039633 0.98028990657456 GO:0035402 histone H3T11 kinase activity 2/362 247/18639 0.00809716599190283 0.416914577135572 0.954590300004516 0.98028990657456 GO:0035403 histone H3T6 kinase activity 2/362 247/18639 0.00809716599190283 0.416914577135572 0.954590300004516 0.98028990657456 GO:0042393 histone binding 2/362 247/18639 0.00809716599190283 0.416914577135572 0.954590300004516 0.98028990657456 GO:0004679 AMP-activated protein kinase activity 2/362 248/18639 0.00806451612903226 0.415233469969702 0.955332030593878 0.98028990657456 GO:0003713 transcription coactivator activity 2/362 256/18639 0.0078125 0.402257424033149 0.960863032191042 0.983505131286027 GO:0015103 inorganic anion transmembrane transporter activity 1/362 165/18639 0.00606060606060606 0.312054244098443 0.961247589418168 0.983505131286027 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 1/362 167/18639 0.00598802395209581 0.308317067522414 0.962751465261074 0.983620355404016 GO:0140030 modification-dependent protein binding 1/362 173/18639 0.00578034682080925 0.297623990036087 0.966922755382965 0.985980591309108 GO:0004721 phosphoprotein phosphatase activity 1/362 175/18639 0.00571428571428571 0.294222573007103 0.968206944061429 0.985980591309108 GO:0061630 ubiquitin protein ligase activity 3/362 353/18639 0.0084985835694051 0.437583146823596 0.969245418613621 0.985980591309108 GO:0106310 protein serine kinase activity 3/362 361/18639 0.00831024930747922 0.427886013375981 0.972734376316189 0.988108051803944 GO:0046943 carboxylic acid transmembrane transporter activity 1/362 188/18639 0.00531914893617021 0.273877395086399 0.975424318690519 0.988489803478594 GO:0005342 organic acid transmembrane transporter activity 1/362 189/18639 0.00529100529100529 0.272428308339911 0.975906482076462 0.988489803478594 GO:0004674 protein serine/threonine kinase activity 3/362 433/18639 0.0069284064665127 0.356736376047874 0.991073015202941 0.999028758786326 GO:0141003 histone H2AX kinase activity 2/362 354/18639 0.00564971751412429 0.290898024159566 0.9926437011878 0.999028758786326 GO:0140996 histone H3 kinase activity 2/362 357/18639 0.00560224089635854 0.288453502948141 0.993019510376854 0.999028758786326 GO:0046873 metal ion transmembrane transporter activity 3/362 450/18639 0.00666666666666667 0.343259668508287 0.993193847572064 0.999028758786326 GO:0035173 histone kinase activity 2/362 360/18639 0.00555555555555556 0.286049723756906 0.993376545158115 0.999028758786326 GO:0016791 phosphatase activity 1/362 273/18639 0.00366300366300366 0.188604213466092 0.995456777672843 0.999132722015698 GO:0005216 monoatomic ion channel activity 2/362 448/18639 0.00446428571428571 0.2298613851618 0.998615673830067 0.999132722015698 GO:0005261 monoatomic cation channel activity 1/362 341/18639 0.00293255131964809 0.150993989079892 0.998829479383761 0.999132722015698 GO:0045182 translation regulator activity 1/362 356/18639 0.00280898876404494 0.144631882798436 0.999132722015698 0.999132722015698