category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Organismal Systems	Immune system	hsa04610	Complement and coagulation cascades	5/61	88/9376	8.73323397913562	CFD/C3/C1R/F2R/SERPING1	5.89794216179036
Cellular Processes	Cell motility	hsa04820	Cytoskeleton in muscle cells	7/61	233/9376	4.61774431858158	VCAN/DCN/LMOD1/MYL9/NID1/COL1A2/MYH11	4.52512517111784
Environmental Information Processing	Signaling molecules and interaction	hsa04060	Cytokine-cytokine receptor interaction	7/61	298/9376	3.61051820882385	CXCL14/PRLR/CXCL3/PRL/CCL3/IL15/IL1R1	3.70594436942252
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	6/61	238/9376	3.87491389998622	CFD/C3/C1R/RPLP0/RPL12/RPS18	3.63535536314374
Human Diseases	Infectious disease: parasitic	hsa05146	Amoebiasis	4/61	103/9376	5.96912303039949	CXCL3/LAMB1/IL1R1/COL1A2	4.10343310741472
Human Diseases	Cancer: overview	hsa05205	Proteoglycans in cancer	5/61	204/9376	3.76727740276438	DCN/TIMP3/LUM/MMP2/COL1A2	3.23366393865158
Organismal Systems	Circulatory system	hsa04270	Vascular smooth muscle contraction	4/61	134/9376	4.5882065084414	RAMP1/MYL9/CALD1/MYH11	3.3853686862879
Human Diseases	Infectious disease: bacterial	hsa05133	Pertussis	3/61	78/9376	5.91172761664565	C3/C1R/SERPING1	3.52489294248804
Cellular Processes	Cell motility	hsa04810	Regulation of actin cytoskeleton	5/61	232/9376	3.31260599208592	TMSB4X/MYL9/F2R/GSN/MYH11	2.88626801362445
NA	NA	hsa04518	Integrin signaling	4/61	154/9376	3.99233553331914	FERMT2/C3/LAMB1/COL1A2	3.02982271565664
Organismal Systems	Digestive system	hsa04970	Salivary secretion	3/61	93/9376	4.95822316234796	CST3/CST2/ATP2B4	3.10425007991965
Human Diseases	Immune disease	hsa05323	Rheumatoid arthritis	3/61	95/9376	4.85383951682485	CXCL3/CCL3/IL15	3.05504187918557
Human Diseases	Infectious disease: bacterial	hsa05150	Staphylococcus aureus infection	3/61	99/9376	4.65772478887233	CFD/C3/C1R	2.96062887623582
Environmental Information Processing	Signaling molecules and interaction	hsa04061	Viral protein interaction with cytokine and cytokine receptor	3/61	100/9376	4.61114754098361	CXCL14/CXCL3/CCL3	2.93781192191109
Environmental Information Processing	Signal transduction	hsa04151	PI3K-Akt signaling pathway	6/61	362/9376	2.54759532651028	PRLR/GNG4/PRL/LAMB1/F2R/COL1A2	2.4300322874602
Organismal Systems	Immune system	hsa04062	Chemokine signaling pathway	4/61	193/9376	3.18559415611994	CXCL14/GNG4/CXCL3/CCL3	2.48264720737189
Organismal Systems	Immune system	hsa04670	Leukocyte transendothelial migration	3/61	116/9376	3.97512719050311	MMP2/THY1/MYL9	2.60908461844457
Human Diseases	Infectious disease: bacterial	hsa05134	Legionellosis	2/61	56/9376	5.48946135831382	C3/CXCL3	2.72671295327964
Organismal Systems	Endocrine system	hsa04926	Relaxin signaling pathway	3/61	130/9376	3.54703656998739	MMP2/GNG4/COL1A2	2.36640480361947
NA	NA	hsa04081	Hormone signaling	4/61	219/9376	2.80739576315592	RAMP1/PRLR/GNG4/PRL	2.19006919377499
Genetic Information Processing	Translation	hsa03010	Ribosome	4/61	222/9376	2.76945798257274	MT-RNR2/RPLP0/RPL12/RPS18	2.15908834795599
Organismal Systems	Endocrine system	hsa04917	Prolactin signaling pathway	2/61	71/9376	4.32971600092357	PRLR/PRL	2.27896316038695
Environmental Information Processing	Signaling molecules and interaction	hsa04080	Neuroactive ligand-receptor interaction	5/61	370/9376	2.07709348692955	C3/PRLR/PRL/P2RY14/F2R	1.71059585985785
Environmental Information Processing	Signal transduction	hsa04022	cGMP-PKG signaling pathway	3/61	166/9376	2.7777997234841	RGS2/MYL9/ATP2B4	1.87010585240548
Environmental Information Processing	Signal transduction	hsa04630	JAK-STAT signaling pathway	3/61	168/9376	2.74473067915691	PRLR/PRL/IL15	1.84654335693714
NA	NA	hsa03273	Virion - Lassa virus and SFTS virus	1/61	17/9376	9.04146576663452	MYH11	2.68536967700656
Environmental Information Processing	Signal transduction	hsa04310	Wnt signaling pathway	3/61	178/9376	2.59053232639528	DKK1/MCC/SERPINF1	1.73366397538829
Environmental Information Processing	Signaling molecules and interaction	hsa04512	ECM-receptor interaction	2/61	89/9376	3.45404310186038	LAMB1/COL1A2	1.88234226125841
Organismal Systems	Nervous system	hsa04727	GABAergic synapse	2/61	89/9376	3.45404310186038	GNG4/PLCL1	1.88234226125841
Organismal Systems	Development and regeneration	hsa04360	Axon guidance	3/61	184/9376	2.50605844618674	MYL9/TRPC4/ABLIM1	1.66957085865698
Human Diseases	Infectious disease: viral	hsa05167	Kaposi sarcoma-associated herpesvirus infection	3/61	196/9376	2.35262629642021	C3/GNG4/CXCL3	1.54861566290216
Human Diseases	Endocrine and metabolic disease	hsa04933	AGE-RAGE signaling pathway in diabetic complications	2/61	101/9376	3.0436617432235	MMP2/COL1A2	1.67098237445982
Human Diseases	Infectious disease: bacterial	hsa05130	Pathogenic Escherichia coli infection	3/61	200/9376	2.3055737704918	F2R/IL1R1/MYH11	1.5102499771099
Human Diseases	Infectious disease: parasitic	hsa05142	Chagas disease	2/61	103/9376	2.98456151519974	C3/CCL3	1.63882346549932
Cellular Processes	Cellular community - eukaryotes	hsa04510	Focal adhesion	3/61	203/9376	2.27150125171606	LAMB1/MYL9/COL1A2	1.48206837542614
Environmental Information Processing	Signal transduction	hsa04064	NF-kappa B signaling pathway	2/61	105/9376	2.92771272443404	CXCL3/IL1R1	1.60743270080214
Environmental Information Processing	Signal transduction	hsa04668	TNF signaling pathway	2/61	119/9376	2.58327593332415	CXCL3/IL15	1.4065464703271
Environmental Information Processing	Signal transduction	hsa04024	cAMP signaling pathway	3/61	226/9376	2.04033077034673	MYL9/F2R/ATP2B4	1.28107407541815
Human Diseases	Infectious disease: viral	hsa05163	Human cytomegalovirus infection	3/61	227/9376	2.03134252906767	GNG4/CCL3/IL1R1	1.27288206661121
Metabolism	Carbohydrate metabolism	hsa00030	Pentose phosphate pathway	1/61	31/9376	4.95822316234796	PRPS2	1.78628436102701
Organismal Systems	Immune system	hsa04611	Platelet activation	2/61	126/9376	2.43976060369503	F2R/COL1A2	1.31663021696484
Organismal Systems	Environmental adaptation	hsa04710	Circadian rhythm	1/61	34/9376	4.52073288331726	RORB	1.66422380439958
Human Diseases	Infectious disease: bacterial	hsa05131	Shigellosis	3/61	253/9376	1.82258796086309	C3/MYL9/IL1R1	1.07332908565607
Human Diseases	Cancer: specific types	hsa05219	Bladder cancer	1/61	41/9376	3.74890043982407	MMP2	1.42742370282281
Human Diseases	Cardiovascular disease	hsa05418	Fluid shear stress and atherosclerosis	2/61	142/9376	2.16485800046179	MMP2/IL1R1	1.13183038822168
Human Diseases	Immune disease	hsa05322	Systemic lupus erythematosus	2/61	143/9376	2.14971913332569	C3/C1R	1.12110808843981
Human Diseases	Endocrine and metabolic disease	hsa04936	Alcoholic liver disease	2/61	144/9376	2.13479052823315	C3/CXCL3	1.11047344196355
Organismal Systems	Endocrine system	hsa04921	Oxytocin signaling pathway	2/61	154/9376	1.99616776665957	RGS2/MYL9	1.00864749103931
Cellular Processes	Transport and catabolism	hsa04145	Phagosome	2/61	155/9376	1.98328926493919	C3/C1R	0.998889072079295
Organismal Systems	Immune system	hsa04672	Intestinal immune network for IgA production	1/61	50/9376	3.07409836065574	IL15	1.18994193793544
Organismal Systems	Excretory system	hsa04961	Endocrine and other factor-regulated calcium reabsorption	1/61	53/9376	2.90009279307145	ATP2B4	1.12251984981452
Genetic Information Processing	Replication and repair	hsa03460	Fanconi anemia pathway	1/61	54/9376	2.84638737097753	REV3L	1.10109369970686
Cellular Processes	Cellular community - eukaryotes	hsa04530	Tight junction	2/61	170/9376	1.8082931533269	MYL9/MYH11	0.86063103221519
Environmental Information Processing	Signal transduction	hsa04340	Hedgehog signaling pathway	1/61	56/9376	2.74473067915691	GAS1	1.05967717798296
Organismal Systems	Digestive system	hsa04978	Mineral absorption	1/61	61/9376	2.51975275463585	ATP2B4	0.963619440827985
Organismal Systems	Aging	hsa04213	Longevity regulating pathway - multiple species	1/61	62/9376	2.47911158117398	CRYAB	0.945557168706802
Organismal Systems	Immune system	hsa04621	NOD-like receptor signaling pathway	2/61	187/9376	1.64390286666082	TXNIP/CXCL3	0.719724293677264
Organismal Systems	Endocrine system	hsa04929	GnRH secretion	1/61	65/9376	2.36469104665826	TRPC4	0.893412415335129
Cellular Processes	Cell motility	hsa04814	Motor proteins	2/61	194/9376	1.58458678384316	MYL9/MYH11	0.665794709052825
Human Diseases	Infectious disease: bacterial	hsa05120	Epithelial cell signaling in Helicobacter pylori infection	1/61	71/9376	2.16485800046179	CXCL3	0.797265733593521
NA	NA	hsa04082	Neuroactive ligand signaling	2/61	199/9376	1.54477304555565	GNG4/P2RY14	0.628566034728111
Human Diseases	Cancer: overview	hsa05202	Transcriptional misregulation in cancer	2/61	201/9376	1.52940216948047	ZEB1/NFKBIZ	0.613959657345508
Human Diseases	Cancer: overview	hsa05203	Viral carcinogenesis	2/61	205/9376	1.49956017592963	C3/GSN	0.585215095016623
Human Diseases	Cardiovascular disease	hsa05415	Diabetic cardiomyopathy	2/61	205/9376	1.49956017592963	MMP2/COL1A2	0.585215095016623
Metabolism	Global and overview maps	hsa01230	Biosynthesis of amino acids	1/61	75/9376	2.04939890710382	PRPS2	0.738355549104093
Human Diseases	Drug resistance: antineoplastic	hsa01524	Platinum drug resistance	1/61	75/9376	2.04939890710382	REV3L	0.738355549104093
Human Diseases	Infectious disease: parasitic	hsa05140	Leishmaniasis	1/61	78/9376	1.97057587221522	C3	0.696532118459982
Human Diseases	Cardiovascular disease	hsa05417	Lipid and atherosclerosis	2/61	216/9376	1.42319368548877	CXCL3/CCL3	0.509187160112504
Human Diseases	Infectious disease: viral	hsa05166	Human T-cell leukemia virus 1 infection	2/61	224/9376	1.37236533957845	IL15/IL1R1	0.456451226970517
Human Diseases	Substance dependence	hsa05032	Morphine addiction	1/61	91/9376	1.68906503332733	GNG4	0.534501687120191
Cellular Processes	Cellular community - eukaryotes	hsa04520	Adherens junction	1/61	93/9376	1.65274105411599	MYL9	0.511914408636939
Organismal Systems	Endocrine system	hsa04912	GnRH signaling pathway	1/61	93/9376	1.65274105411599	MMP2	0.511914408636939
Human Diseases	Cancer: specific types	hsa05222	Small cell lung cancer	1/61	93/9376	1.65274105411599	LAMB1	0.511914408636939
Organismal Systems	Immune system	hsa04657	IL-17 signaling pathway	1/61	94/9376	1.63515870247646	CXCL3	0.500823297889641
Organismal Systems	Environmental adaptation	hsa04713	Circadian entrainment	1/61	97/9376	1.58458678384316	GNG4	0.468320747843128
Organismal Systems	Immune system	hsa04666	Fc gamma R-mediated phagocytosis	1/61	98/9376	1.5684175309468	GSN	0.457733231772508
Organismal Systems	Endocrine system	hsa04925	Aldosterone synthesis and secretion	1/61	98/9376	1.5684175309468	ATP2B4	0.457733231772508
Human Diseases	Drug resistance: antineoplastic	hsa01522	Endocrine resistance	1/61	99/9376	1.55257492962411	MMP2	0.44726418398293
Organismal Systems	Sensory system	hsa04750	Inflammatory mediator regulation of TRP channels	1/61	99/9376	1.55257492962411	IL1R1	0.44726418398293
Organismal Systems	Immune system	hsa04640	Hematopoietic cell lineage	1/61	100/9376	1.53704918032787	IL1R1	0.436910834219208
Organismal Systems	Digestive system	hsa04972	Pancreatic secretion	1/61	102/9376	1.50691096110575	ATP2B4	0.41654060972804
Organismal Systems	Digestive system	hsa04974	Protein digestion and absorption	1/61	103/9376	1.49228075759987	COL1A2	0.406518644541614
Environmental Information Processing	Signal transduction	hsa04020	Calcium signaling pathway	2/61	254/9376	1.21027494514005	F2R/ATP2B4	0.274927687299669
Human Diseases	Cancer: specific types	hsa05215	Prostate cancer	1/61	106/9376	1.45004639653573	ZEB1	0.377076511309139
Organismal Systems	Immune system	hsa04620	Toll-like receptor signaling pathway	1/61	109/9376	1.41013686268612	CCL3	0.348523124276768
Organismal Systems	Immune system	hsa04659	Th17 cell differentiation	1/61	109/9376	1.41013686268612	IL1R1	0.348523124276768
Environmental Information Processing	Signal transduction	hsa04350	TGF-beta signaling pathway	1/61	110/9376	1.3973174366617	DCN	0.339193050451143
Human Diseases	Infectious disease: parasitic	hsa05145	Toxoplasmosis	1/61	112/9376	1.37236533957845	LAMB1	0.320802772914364
Organismal Systems	Nervous system	hsa04725	Cholinergic synapse	1/61	115/9376	1.33656450463293	GNG4	0.293864696998185
Organismal Systems	Nervous system	hsa04726	Serotonergic synapse	1/61	115/9376	1.33656450463293	GNG4	0.293864696998185
Metabolism	Global and overview maps	hsa01200	Carbon metabolism	1/61	116/9376	1.32504239683437	PRPS2	0.285051046096453
Organismal Systems	Nervous system	hsa04724	Glutamatergic synapse	1/61	116/9376	1.32504239683437	GNG4	0.285051046096453
Environmental Information Processing	Signal transduction	hsa04152	AMPK signaling pathway	1/61	122/9376	1.25987637731793	CAB39L	0.233798164834343
Metabolism	Nucleotide metabolism	hsa00230	Purine metabolism	1/61	128/9376	1.20081967213115	PRPS2	0.185117064176699
Organismal Systems	Nervous system	hsa04728	Dopaminergic synapse	1/61	133/9376	1.15567607543449	GNG4	0.146318872070518
NA	NA	hsa04517	IgSF CAM signaling	2/61	299/9376	1.02812654202533	MYL9/MYH11	0.0399981490386319
Cellular Processes	Cell growth and death	hsa04210	Apoptosis	1/61	137/9376	1.12193370826852	PTPN13	0.116340441602769
Organismal Systems	Endocrine system	hsa04915	Estrogen signaling pathway	1/61	139/9376	1.10579077721429	MMP2	0.101683119703416
Environmental Information Processing	Signal transduction	hsa04371	Apelin signaling pathway	1/61	140/9376	1.09789227166276	GNG4	0.0944342615393179
Organismal Systems	Development and regeneration	hsa04380	Osteoclast differentiation	1/61	142/9376	1.08242900023089	IL1R1	0.0800918629524556
Cellular Processes	Cellular community - eukaryotes	hsa04550	Signaling pathways regulating pluripotency of stem cells	1/61	144/9376	1.06739526411658	TBX3	0.0659510711920567
Environmental Information Processing	Signal transduction	hsa04072	Phospholipase D signaling pathway	1/61	149/9376	1.03157663109253	F2R	0.0314403804965252
Organismal Systems	Nervous system	hsa04723	Retrograde endocannabinoid signaling	1/61	149/9376	1.03157663109253	GNG4	0.0314403804965252
Human Diseases	Cancer: overview	hsa05206	MicroRNAs in cancer	2/61	323/9376	0.951733238593108	TIMP3/ZEB1	-0.0714352035669069
Organismal Systems	Circulatory system	hsa04261	Adrenergic signaling in cardiomyocytes	1/61	154/9376	0.998083883329785	ATP2B4	-0.00194012126936396
Human Diseases	Infectious disease: viral	hsa05165	Human papillomavirus infection	2/61	333/9376	0.923152660857579	LAMB1/COL1A2	-0.115545706384076
Cellular Processes	Transport and catabolism	hsa04148	Efferocytosis	1/61	157/9376	0.979012216769343	MFGE8	-0.0214601925738913
Environmental Information Processing	Signal transduction	hsa04150	mTOR signaling pathway	1/61	158/9376	0.972815936916373	CAB39L	-0.0278858371638453
Environmental Information Processing	Signaling molecules and interaction	hsa04514	Cell adhesion molecule (CAM) interaction	1/61	160/9376	0.960655737704918	VCAN	-0.0406190059655217
Genetic Information Processing	Folding, sorting and degradation	hsa04141	Protein processing in endoplasmic reticulum	1/61	174/9376	0.88336159788958	CRYAB	-0.125670747166855
Human Diseases	Infectious disease: viral	hsa05168	Herpes simplex virus 1 infection	1/61	180/9376	0.85391621129326	C3	-0.160139298298848
Human Diseases	Infectious disease: bacterial	hsa05152	Tuberculosis	1/61	181/9376	0.849198442170093	C3	-0.165778564499951
Human Diseases	Substance dependence	hsa05034	Alcoholism	1/61	191/9376	0.804737790747575	GNG4	-0.220624850338311
Organismal Systems	Immune system	hsa04613	Neutrophil extracellular trap formation	1/61	195/9376	0.788230348886087	C3	-0.241821638348075
Environmental Information Processing	Signal transduction	hsa04015	Rap1 signaling pathway	1/61	212/9376	0.725023198267863	F2R	-0.327703117294918
Human Diseases	Infectious disease: viral	hsa05170	Human immunodeficiency virus 1 infection	1/61	214/9376	0.718247280527042	GNG4	-0.337395266687427
Environmental Information Processing	Signal transduction	hsa04014	Ras signaling pathway	1/61	238/9376	0.645818983331037	GNG4	-0.447865189450503
Human Diseases	Infectious disease: bacterial	hsa05132	Salmonella infection	1/61	248/9376	0.619777895293495	MYL9	-0.491059946682158
Cellular Processes	Transport and catabolism	hsa04144	Endocytosis	1/61	250/9376	0.614819672131148	RAB31	-0.499520132649374
Environmental Information Processing	Signal transduction	hsa04010	MAPK signaling pathway	1/61	300/9376	0.512349726775956	IL1R1	-0.694673899480743
Human Diseases	Neurodegenerative disease	hsa05016	Huntington disease	1/61	308/9376	0.499041941664892	TGM2	-0.723402650416368
Human Diseases	Neurodegenerative disease	hsa05010	Alzheimer disease	1/61	388/9376	0.396146695960791	DKK1	-0.9830484073841
NA	NA	hsa04519	Cadherin signaling	1/61	404/9376	0.380457717902938	CDH11	-1.03009226806936
Organismal Systems	Sensory system	hsa04740	Olfactory transduction	1/61	449/9376	0.342327211654314	RGS2	-1.1556848023887
Human Diseases	Neurodegenerative disease	hsa05022	Pathways of neurodegeneration - multiple diseases	1/61	480/9376	0.320218579234973	DKK1	-1.23723343618858