ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0003823	antigen binding	29/495	174/18639	0.166666666666667	6.27575757575758	2.27858408928862e-15	1.71577381923433e-12
GO:0140375	immune receptor activity	22/495	156/18639	0.141025641025641	5.31025641025641	1.67168923347998e-10	6.29390996405212e-08
GO:0042608	T cell receptor binding	7/495	11/18639	0.636363636363636	23.9619834710744	2.68856406682635e-09	6.74829580773413e-07
GO:0023023	MHC protein complex binding	10/495	37/18639	0.27027027027027	10.1769041769042	2.916431983403e-08	5.49018320875615e-06
GO:0042605	peptide antigen binding	10/495	45/18639	0.222222222222222	8.36767676767677	2.20739092616335e-07	2.95969707901438e-05
GO:0004896	cytokine receptor activity	14/495	96/18639	0.145833333333333	5.49128787878788	2.35832436574851e-07	2.95969707901438e-05
GO:0019955	cytokine binding	17/495	144/18639	0.118055555555556	4.44532828282828	2.86658925312955e-07	3.0836310108665e-05
GO:0023026	MHC class II protein complex binding	8/495	27/18639	0.296296296296296	11.1569023569024	3.32854814554951e-07	3.13299594199848e-05
GO:0001968	fibronectin binding	8/495	30/18639	0.266666666666667	10.0412121212121	8.18073423111991e-07	6.84454764003699e-05
GO:0005125	cytokine activity	21/495	234/18639	0.0897435897435897	3.37925407925408	1.24720206851932e-06	9.39143157595045e-05
GO:0005201	extracellular matrix structural constituent	17/495	168/18639	0.101190476190476	3.81028138528139	2.53682330126236e-06	0.000173657085986414
GO:0005178	integrin binding	16/495	161/18639	0.0993788819875776	3.74206662902315	6.3023970649491e-06	0.000395475415825556
GO:0034987	immunoglobulin receptor binding	6/495	19/18639	0.315789473684211	11.8909090909091	6.88033751927776e-06	0.000398530319385858
GO:0003779	actin binding	29/495	443/18639	0.0654627539503386	2.46497024420275	8.30308263968696e-06	0.000446587230548877
GO:0098631	cell adhesion mediator activity	10/495	76/18639	0.131578947368421	4.95454545454545	3.16369136345675e-05	0.00158817306445529
GO:0048020	CCR chemokine receptor binding	8/495	50/18639	0.16	6.02472727272727	4.7081321525858e-05	0.00221576469431069
GO:0032395	MHC class II receptor activity	4/495	10/18639	0.4	15.0618181818182	9.08699210530796e-05	0.00397710309119752
GO:0140313	molecular sequestering activity	8/495	55/18639	0.145454545454545	5.47702479338843	9.50701934150802e-05	0.00397710309119752
GO:0061134	peptidase regulator activity	17/495	226/18639	0.0752212389380531	2.83242156074015	0.000119357069306972	0.0047303091151658
GO:0008009	chemokine activity	7/495	45/18639	0.155555555555556	5.85737373737374	0.000169034442292192	0.006080808227987
GO:0019887	protein kinase regulator activity	18/495	255/18639	0.0705882352941176	2.6579679144385	0.000169584293210793	0.006080808227987
GO:0015026	coreceptor activity	8/495	61/18639	0.131147540983607	4.93830104321908	0.000200084071954923	0.00670613078468963
GO:0019956	chemokine binding	6/495	33/18639	0.181818181818182	6.84628099173554	0.000204835336052937	0.00670613078468963
GO:0043495	protein-membrane adaptor activity	7/495	47/18639	0.148936170212766	5.60812379110251	0.000223793755349098	0.00702152907407796
GO:0019838	growth factor binding	12/495	136/18639	0.0882352941176471	3.32245989304813	0.000277621873251014	0.00836197082232053
GO:0016763	pentosyltransferase activity	7/495	49/18639	0.142857142857143	5.37922077922078	0.000292018095270137	0.00845729329763129
GO:0038024	cargo receptor activity	8/495	65/18639	0.123076923076923	4.63440559440559	0.000312621118635825	0.00871865564195468
GO:0004857	enzyme inhibitor activity	24/495	416/18639	0.0576923076923077	2.17237762237762	0.00033717321628551	0.00906755113796391
GO:0042277	peptide binding	17/495	249/18639	0.0682730923694779	2.57079225994889	0.000376308252893376	0.00965766631452248
GO:0004860	protein kinase inhibitor activity	9/495	84/18639	0.107142857142857	4.03441558441558	0.000384767582251892	0.00965766631452248
GO:0001637	G protein-coupled chemoattractant receptor activity	5/495	26/18639	0.192307692307692	7.24125874125874	0.000536558771883851	0.0126258986008919
GO:0004950	chemokine receptor activity	5/495	26/18639	0.192307692307692	7.24125874125874	0.000536558771883851	0.0126258986008919
GO:0098632	cell-cell adhesion mediator activity	7/495	55/18639	0.127272727272727	4.79239669421488	0.000601624099282946	0.0134235563357443
GO:0005518	collagen binding	8/495	72/18639	0.111111111111111	4.18383838383838	0.000630651748691329	0.0134235563357443
GO:0042379	chemokine receptor binding	8/495	72/18639	0.111111111111111	4.18383838383838	0.000630651748691329	0.0134235563357443
GO:0019210	kinase inhibitor activity	9/495	90/18639	0.1	3.76545454545455	0.000641763649517657	0.0134235563357443
GO:0019207	kinase regulator activity	18/495	287/18639	0.0627177700348432	2.36160912258473	0.000702402122512559	0.014294832385188
GO:0044325	transmembrane transporter binding	11/495	136/18639	0.0808823529411765	3.04558823529412	0.00102258652869868	0.0202633593713186
GO:0005126	cytokine receptor binding	17/495	275/18639	0.0618181818181818	2.32773553719008	0.00114585077580059	0.0221237342096882
GO:0051015	actin filament binding	14/495	209/18639	0.0669856459330144	2.52231404958678	0.0014435315169143	0.0271744808059117
GO:0005031	tumor necrosis factor receptor activity	3/495	10/18639	0.3	11.2963636363636	0.00194359707555723	0.0343752827626158
GO:0031720	haptoglobin binding	3/495	10/18639	0.3	11.2963636363636	0.00194359707555723	0.0343752827626158
GO:0050840	extracellular matrix binding	7/495	67/18639	0.104477611940299	3.93405698778833	0.00196299755483729	0.0343752827626158
GO:0016209	antioxidant activity	8/495	86/18639	0.0930232558139535	3.50274841437632	0.00202569593804835	0.0346670236670547
GO:0005539	glycosaminoglycan binding	15/495	242/18639	0.0619834710743802	2.33395942900075	0.00213365193039678	0.0357031089686395
GO:0001664	G protein-coupled receptor binding	17/495	297/18639	0.0572390572390572	2.15531068258341	0.00259063697544601	0.0419760732688328
GO:0001851	complement component C3b binding	3/495	11/18639	0.272727272727273	10.2694214876033	0.00262002050947562	0.0419760732688328
GO:0043394	proteoglycan binding	5/495	37/18639	0.135135135135135	5.08845208845209	0.00279782779279081	0.0430148402512259
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	4/495	23/18639	0.173913043478261	6.54861660079051	0.00291335571422646	0.0430148402512259
GO:0016493	C-C chemokine receptor activity	4/495	23/18639	0.173913043478261	6.54861660079051	0.00291335571422646	0.0430148402512259
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	4/495	23/18639	0.173913043478261	6.54861660079051	0.00291335571422646	0.0430148402512259
GO:0005540	hyaluronic acid binding	4/495	24/18639	0.166666666666667	6.27575757575758	0.00342358454897579	0.0486407389694107
GO:0019957	C-C chemokine binding	4/495	24/18639	0.166666666666667	6.27575757575758	0.00342358454897579	0.0486407389694107
GO:0061135	endopeptidase regulator activity	12/495	184/18639	0.0652173913043478	2.45573122529644	0.00382027245409495	0.0527274714786276
GO:0004601	peroxidase activity	6/495	57/18639	0.105263157894737	3.96363636363636	0.00392699742172695	0.0527274714786276
GO:0016504	peptidase activator activity	6/495	57/18639	0.105263157894737	3.96363636363636	0.00392699742172695	0.0527274714786276
GO:0001848	complement binding	4/495	25/18639	0.16	6.02472727272727	0.00399132254220687	0.0527274714786276
GO:0005035	death receptor activity	3/495	13/18639	0.230769230769231	8.68951048951049	0.00436529718372285	0.0544458874315668
GO:0031994	insulin-like growth factor I binding	3/495	13/18639	0.230769230769231	8.68951048951049	0.00436529718372285	0.0544458874315668
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	5/495	41/18639	0.121951219512195	4.5920177383592	0.00441062301902467	0.0544458874315668
GO:0042169	SH2 domain binding	5/495	41/18639	0.121951219512195	4.5920177383592	0.00441062301902467	0.0544458874315668
GO:0043548	phosphatidylinositol 3-kinase binding	4/495	26/18639	0.153846153846154	5.79300699300699	0.00461946140953833	0.0557518452019437
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	6/495	59/18639	0.101694915254237	3.82927580893683	0.00466449700892756	0.0557518452019437
GO:0005044	scavenger receptor activity	4/495	27/18639	0.148148148148148	5.57845117845118	0.00531080020359835	0.0594465205578817
GO:0019001	guanyl nucleotide binding	20/495	400/18639	0.05	1.88272727272727	0.0053317772681439	0.0594465205578817
GO:0032561	guanyl ribonucleotide binding	20/495	400/18639	0.05	1.88272727272727	0.0053317772681439	0.0594465205578817
GO:0016757	glycosyltransferase activity	15/495	267/18639	0.0561797752808989	2.11542390194076	0.00534785265820683	0.0594465205578817
GO:0005344	oxygen carrier activity	3/495	14/18639	0.214285714285714	8.06883116883117	0.00544729072841147	0.0594465205578817
GO:0008191	metalloendopeptidase inhibitor activity	3/495	14/18639	0.214285714285714	8.06883116883117	0.00544729072841147	0.0594465205578817
GO:0030414	peptidase inhibitor activity	11/495	169/18639	0.0650887573964497	2.4508875739645	0.00557785042351055	0.0600017338414777
GO:0001618	virus receptor activity	7/495	81/18639	0.0864197530864197	3.25409652076319	0.00572092728622852	0.0606740598102828
GO:0045499	chemorepellent activity	4/495	28/18639	0.142857142857143	5.37922077922078	0.00606803849465017	0.0619589554381488
GO:0097718	disordered domain specific binding	4/495	28/18639	0.142857142857143	5.37922077922078	0.00606803849465017	0.0619589554381488
GO:0140272	exogenous protein binding	7/495	82/18639	0.0853658536585366	3.21441241685144	0.00611565983465561	0.0619589554381488
GO:0005525	GTP binding	19/495	378/18639	0.0502645502645503	1.89268879268879	0.00617121070101084	0.0619589554381488
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	3/495	15/18639	0.2	7.53090909090909	0.00667627079660718	0.0644516911518616
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	3/495	15/18639	0.2	7.53090909090909	0.00667627079660718	0.0644516911518616
GO:0051371	muscle alpha-actinin binding	3/495	15/18639	0.2	7.53090909090909	0.00667627079660718	0.0644516911518616
GO:0043236	laminin binding	4/495	29/18639	0.137931034482759	5.19373040752351	0.0068937704152306	0.0657089762363119
GO:0030291	protein serine/threonine kinase inhibitor activity	5/495	46/18639	0.108695652173913	4.09288537549407	0.00724168468261132	0.068162357075079
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	3/495	16/18639	0.1875	7.06022727272727	0.00805686324534112	0.0748989879474304
GO:0038191	neuropilin binding	3/495	17/18639	0.176470588235294	6.64491978609626	0.00959299884957827	0.0880918065089322
GO:0140311	protein sequestering activity	4/495	33/18639	0.121212121212121	4.56418732782369	0.0109295590755582	0.0983616646077895
GO:0004866	endopeptidase inhibitor activity	10/495	161/18639	0.062111801242236	2.33879164313947	0.0109726159721837	0.0983616646077895
GO:0008083	growth factor activity	10/495	162/18639	0.0617283950617284	2.32435465768799	0.0114269377777862	0.101229225254977
GO:0004713	protein tyrosine kinase activity	9/495	140/18639	0.0642857142857143	2.42064935064935	0.0125244139759285	0.107584063362218
GO:1990782	protein tyrosine kinase binding	8/495	117/18639	0.0683760683760684	2.57466977466978	0.0128337021697824	0.107584063362218
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	3/495	19/18639	0.157894736842105	5.94545454545455	0.0131444008357557	0.107584063362218
GO:0005520	insulin-like growth factor binding	3/495	19/18639	0.157894736842105	5.94545454545455	0.0131444008357557	0.107584063362218
GO:0008301	DNA binding, bending	3/495	19/18639	0.157894736842105	5.94545454545455	0.0131444008357557	0.107584063362218
GO:0030506	ankyrin binding	3/495	19/18639	0.157894736842105	5.94545454545455	0.0131444008357557	0.107584063362218
GO:0043395	heparan sulfate proteoglycan binding	3/495	19/18639	0.157894736842105	5.94545454545455	0.0131444008357557	0.107584063362218
GO:0008236	serine-type peptidase activity	11/495	194/18639	0.0567010309278351	2.13505154639175	0.014826607998563	0.120047697020623
GO:0017171	serine hydrolase activity	11/495	198/18639	0.0555555555555556	2.09191919191919	0.0170111674651067	0.134682906520798
GO:0045296	cadherin binding	16/495	334/18639	0.0479041916167665	1.80381056069679	0.017254378386451	0.134682906520798
GO:0001846	opsonin binding	3/495	21/18639	0.142857142857143	5.37922077922078	0.0173495908798372	0.134682906520798
GO:0009931	calcium-dependent protein serine/threonine kinase activity	3/495	21/18639	0.142857142857143	5.37922077922078	0.0173495908798372	0.134682906520798
GO:0004177	aminopeptidase activity	4/495	40/18639	0.1	3.76545454545455	0.0211217725377435	0.160653482029503
GO:0015036	disulfide oxidoreductase activity	4/495	40/18639	0.1	3.76545454545455	0.0211217725377435	0.160653482029503
GO:0004714	transmembrane receptor protein tyrosine kinase activity	5/495	60/18639	0.0833333333333333	3.13787878787879	0.0213698504329954	0.160914973760456
GO:0004602	glutathione peroxidase activity	3/495	23/18639	0.130434782608696	4.91146245059288	0.0222190873965306	0.16565319613453
GO:0030215	semaphorin receptor binding	3/495	24/18639	0.125	4.70681818181818	0.0249041592318955	0.183851293153111
GO:0051087	protein-folding chaperone binding	8/495	134/18639	0.0597014925373134	2.24803256445048	0.0267106177176267	0.195272768362844
GO:0008239	dipeptidyl-peptidase activity	2/495	10/18639	0.2	7.53090909090909	0.0275036217215322	0.197171698077868
GO:0070513	death domain binding	2/495	10/18639	0.2	7.53090909090909	0.0275036217215322	0.197171698077868
GO:0019211	phosphatase activator activity	3/495	25/18639	0.12	4.51854545454545	0.0277559096895804	0.197171698077868
GO:0005096	GTPase activator activity	13/495	271/18639	0.0479704797047971	1.80630660852063	0.0296177638963475	0.208431553401399
GO:0008198	ferrous iron binding	3/495	26/18639	0.115384615384615	4.34475524475524	0.030773707291325	0.212592675140988
GO:0070006	metalloaminopeptidase activity	3/495	26/18639	0.115384615384615	4.34475524475524	0.030773707291325	0.212592675140988
GO:0003924	GTPase activity	15/495	331/18639	0.0453172205438066	1.70639934084043	0.0317905821963746	0.217620985398819
GO:0008199	ferric iron binding	2/495	11/18639	0.181818181818182	6.84628099173554	0.0330333108797671	0.218193711337409
GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	2/495	11/18639	0.181818181818182	6.84628099173554	0.0330333108797671	0.218193711337409
GO:0019864	IgG binding	2/495	11/18639	0.181818181818182	6.84628099173554	0.0330333108797671	0.218193711337409
GO:0050998	nitric-oxide synthase binding	2/495	11/18639	0.181818181818182	6.84628099173554	0.0330333108797671	0.218193711337409
GO:0032934	sterol binding	5/495	68/18639	0.0735294117647059	2.76871657754011	0.0344091374268269	0.225305047673049
GO:0030246	carbohydrate binding	13/495	280/18639	0.0464285714285714	1.74824675324675	0.0370542803918746	0.24007953408567
GO:0051393	alpha-actinin binding	3/495	28/18639	0.107142857142857	4.03441558441558	0.0373031945392077	0.24007953408567
GO:0019903	protein phosphatase binding	8/495	144/18639	0.0555555555555556	2.09191919191919	0.0385304790618609	0.244442550635573
GO:0042301	phosphate ion binding	2/495	12/18639	0.166666666666667	6.27575757575758	0.0389549881490953	0.244442550635573
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	2/495	12/18639	0.166666666666667	6.27575757575758	0.0389549881490953	0.244442550635573
GO:0001222	transcription corepressor binding	4/495	49/18639	0.0816326530612245	3.07384044526902	0.040719924896339	0.251896857435269
GO:0004629	phospholipase C activity	3/495	29/18639	0.103448275862069	3.89529780564263	0.0408119742458204	0.251896857435269
GO:0051020	GTPase binding	14/495	315/18639	0.0444444444444444	1.67353535353535	0.0426042869075177	0.260821366189926
GO:0004175	endopeptidase activity	17/495	405/18639	0.0419753086419753	1.58056116722783	0.0433384300869217	0.261247392047676
GO:0005006	epidermal growth factor receptor activity	4/495	50/18639	0.08	3.01236363636364	0.0433677609640897	0.261247392047676
GO:0043539	protein serine/threonine kinase activator activity	5/495	73/18639	0.0684931506849315	2.57907845579078	0.0446073655256882	0.264098831171816
GO:0031432	titin binding	2/495	13/18639	0.153846153846154	5.79300699300699	0.0452440228700721	0.264098831171816
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	2/495	13/18639	0.153846153846154	5.79300699300699	0.0452440228700721	0.264098831171816
GO:0140806	NAD+-protein-aspartate ADP-ribosyltransferase activity	2/495	13/18639	0.153846153846154	5.79300699300699	0.0452440228700721	0.264098831171816
GO:0004252	serine-type endopeptidase activity	9/495	176/18639	0.0511363636363636	1.92551652892562	0.0457151483016255	0.264796205162492
GO:0005010	insulin-like growth factor receptor activity	4/495	51/18639	0.0784313725490196	2.95329768270945	0.0461102051431656	0.265045682998502
GO:0005164	tumor necrosis factor receptor binding	3/495	31/18639	0.0967741935483871	3.64398826979472	0.048308225094996	0.27350446237994
GO:0070325	lipoprotein particle receptor binding	3/495	31/18639	0.0967741935483871	3.64398826979472	0.048308225094996	0.27350446237994
GO:0005080	protein kinase C binding	4/495	52/18639	0.0769230769230769	2.8965034965035	0.048947083133161	0.275053385069181
GO:0019763	immunoglobulin receptor activity	2/495	14/18639	0.142857142857143	5.37922077922078	0.0518768115603489	0.281030497157861
GO:0032036	myosin heavy chain binding	2/495	14/18639	0.142857142857143	5.37922077922078	0.0518768115603489	0.281030497157861
GO:0034236	protein kinase A catalytic subunit binding	2/495	14/18639	0.142857142857143	5.37922077922078	0.0518768115603489	0.281030497157861
GO:0044548	S100 protein binding	2/495	14/18639	0.142857142857143	5.37922077922078	0.0518768115603489	0.281030497157861
GO:0071933	Arp2/3 complex binding	2/495	14/18639	0.142857142857143	5.37922077922078	0.0518768115603489	0.281030497157861
GO:0008238	exopeptidase activity	6/495	102/18639	0.0588235294117647	2.21497326203209	0.054448283982418	0.291140242795613
GO:0015485	cholesterol binding	4/495	54/18639	0.0740740740740741	2.78922558922559	0.0549029408724794	0.291140242795613
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	4/495	54/18639	0.0740740740740741	2.78922558922559	0.0549029408724794	0.291140242795613
GO:0019239	deaminase activity	3/495	33/18639	0.0909090909090909	3.42314049586777	0.0564273583497187	0.295095254405963
GO:0019199	transmembrane receptor protein kinase activity	5/495	78/18639	0.0641025641025641	2.41375291375291	0.0564325586114989	0.295095254405963
GO:0008237	metallopeptidase activity	9/495	184/18639	0.0489130434782609	1.84179841897233	0.0574701320477635	0.29844834091011
GO:0008242	omega peptidase activity	2/495	15/18639	0.133333333333333	5.02060606060606	0.0588307409086169	0.302193741779444
GO:0016835	carbon-oxygen lyase activity	5/495	79/18639	0.0632911392405063	2.38319907940161	0.0589939973991744	0.302193741779444
GO:0008376	acetylgalactosaminyltransferase activity	3/495	34/18639	0.0882352941176471	3.32245989304813	0.0607139419494532	0.304783988586255
GO:0015035	protein-disulfide reductase activity	3/495	34/18639	0.0882352941176471	3.32245989304813	0.0607139419494532	0.304783988586255
GO:0019825	oxygen binding	3/495	34/18639	0.0882352941176471	3.32245989304813	0.0607139419494532	0.304783988586255
GO:0048306	calcium-dependent protein binding	5/495	80/18639	0.0625	2.35340909090909	0.0616208154398141	0.307287907458146
GO:0099106	ion channel regulator activity	8/495	160/18639	0.05	1.88272727272727	0.0639199941373319	0.314945357332519
GO:0005521	lamin binding	2/495	16/18639	0.125	4.70681818181818	0.0660841520033706	0.314945357332519
GO:0008142	oxysterol binding	2/495	16/18639	0.125	4.70681818181818	0.0660841520033706	0.314945357332519
GO:0008296	3'-5'-DNA exonuclease activity	2/495	16/18639	0.125	4.70681818181818	0.0660841520033706	0.314945357332519
GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	2/495	16/18639	0.125	4.70681818181818	0.0660841520033706	0.314945357332519
GO:0016722	oxidoreductase activity, acting on metal ions	2/495	16/18639	0.125	4.70681818181818	0.0660841520033706	0.314945357332519
GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	2/495	16/18639	0.125	4.70681818181818	0.0660841520033706	0.314945357332519
GO:0019902	phosphatase binding	9/495	190/18639	0.0473684210526316	1.78363636363636	0.0674611470633404	0.319485809677329
GO:0005496	steroid binding	6/495	108/18639	0.0555555555555556	2.09191919191919	0.0680106219677902	0.320074989635913
GO:0001540	amyloid-beta binding	5/495	83/18639	0.0602409638554217	2.26834611171961	0.06989202261671	0.326886292114178
GO:0140789	histone phosphatase activity	7/495	136/18639	0.0514705882352941	1.93810160427807	0.0708495578978256	0.328006380089815
GO:0015459	potassium channel regulator activity	4/495	59/18639	0.0677966101694915	2.55285053929122	0.0714142919317441	0.328006380089815
GO:0051117	ATPase binding	5/495	84/18639	0.0595238095238095	2.24134199134199	0.0727786139674538	0.328006380089815
GO:0004550	nucleoside diphosphate kinase activity	2/495	17/18639	0.117647058823529	4.42994652406417	0.0736163057572095	0.328006380089815
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	2/495	17/18639	0.117647058823529	4.42994652406417	0.0736163057572095	0.328006380089815
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	2/495	17/18639	0.117647058823529	4.42994652406417	0.0736163057572095	0.328006380089815
GO:0019198	transmembrane receptor protein phosphatase activity	2/495	17/18639	0.117647058823529	4.42994652406417	0.0736163057572095	0.328006380089815
GO:0046965	nuclear retinoid X receptor binding	2/495	17/18639	0.117647058823529	4.42994652406417	0.0736163057572095	0.328006380089815
GO:0042805	actinin binding	3/495	37/18639	0.0810810810810811	3.05307125307125	0.0744459340033944	0.329751695909153
GO:0031267	small GTPase binding	12/495	283/18639	0.0424028268551237	1.59665917121748	0.0758445960991406	0.33398234422604
GO:0030295	protein kinase activator activity	7/495	139/18639	0.0503597122302158	1.89627207325049	0.0775769247515072	0.339624560103982
GO:0016247	channel regulator activity	8/495	168/18639	0.0476190476190476	1.79307359307359	0.0797794741804701	0.34724823154852
GO:0070064	proline-rich region binding	2/495	18/18639	0.111111111111111	4.18383838383838	0.0814073494886055	0.350284195228114
GO:0098641	cadherin binding involved in cell-cell adhesion	2/495	18/18639	0.111111111111111	4.18383838383838	0.0814073494886055	0.350284195228114
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	14/495	349/18639	0.0401146131805158	1.51049752539724	0.0833778974207488	0.356333483185444
GO:0141108	transporter regulator activity	8/495	170/18639	0.0470588235294118	1.77197860962567	0.0840795180531908	0.356333483185444
GO:0004197	cysteine-type endopeptidase activity	5/495	88/18639	0.0568181818181818	2.13946280991735	0.0849642082030249	0.356333483185444
GO:0001221	transcription coregulator binding	6/495	115/18639	0.0521739130434783	1.96458498023715	0.0860936330580582	0.356333483185444
GO:0035401	histone H3Y41 kinase activity	6/495	115/18639	0.0521739130434783	1.96458498023715	0.0860936330580582	0.356333483185444
GO:0140801	histone H2AXY142 kinase activity	6/495	115/18639	0.0521739130434783	1.96458498023715	0.0860936330580582	0.356333483185444
GO:0005507	copper ion binding	4/495	63/18639	0.0634920634920635	2.39076479076479	0.086240649918119	0.356333483185444
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	5/495	89/18639	0.0561797752808989	2.11542390194076	0.0881683840580849	0.356333483185444
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	5/495	89/18639	0.0561797752808989	2.11542390194076	0.0881683840580849	0.356333483185444
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	3/495	40/18639	0.075	2.82409090909091	0.0894167999819647	0.356333483185444
GO:0061791	GTPase motor activity	3/495	40/18639	0.075	2.82409090909091	0.0894167999819647	0.356333483185444
GO:1990606	membrane scission GTPase motor activity	3/495	40/18639	0.075	2.82409090909091	0.0894167999819647	0.356333483185444
GO:0050145	nucleoside monophosphate kinase activity	2/495	19/18639	0.105263157894737	3.96363636363636	0.0894382846242349	0.356333483185444
GO:0070003	threonine-type peptidase activity	2/495	19/18639	0.105263157894737	3.96363636363636	0.0894382846242349	0.356333483185444
GO:0140793	histone H2AXY142 phosphatase activity	5/495	90/18639	0.0555555555555556	2.09191919191919	0.0914347230584795	0.36237024454229
GO:0008194	UDP-glycosyltransferase activity	7/495	145/18639	0.0482758620689655	1.81780564263323	0.0921105082204085	0.36313723921449
GO:0004721	phosphoprotein phosphatase activity	8/495	175/18639	0.0457142857142857	1.72135064935065	0.0954142151294175	0.374202624960684
GO:0016004	phospholipase activator activity	2/495	20/18639	0.1	3.76545454545455	0.0976909354861144	0.375584050187667
GO:0016505	peptidase activator activity involved in apoptotic process	2/495	20/18639	0.1	3.76545454545455	0.0976909354861144	0.375584050187667
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	2/495	20/18639	0.1	3.76545454545455	0.0976909354861144	0.375584050187667
GO:0043178	alcohol binding	5/495	92/18639	0.0543478260869565	2.04644268774704	0.0981516990557238	0.375584050187667
GO:0008235	metalloexopeptidase activity	4/495	66/18639	0.0606060606060606	2.28209366391185	0.0982603690398014	0.375584050187667
GO:0019209	kinase activator activity	7/495	148/18639	0.0472972972972973	1.78095823095823	0.0999112422912219	0.37996548204692
GO:0016500	protein-hormone receptor activity	4/495	67/18639	0.0597014925373134	2.24803256445048	0.102431697517731	0.386338006239826
GO:0005319	lipid transporter activity	8/495	178/18639	0.0449438202247191	1.6923391215526	0.102613016265558	0.386338006239826
GO:0008200	ion channel inhibitor activity	3/495	43/18639	0.0697674418604651	2.62706131078224	0.105529837996982	0.391810701490426
GO:0008375	acetylglucosaminyltransferase activity	3/495	43/18639	0.0697674418604651	2.62706131078224	0.105529837996982	0.391810701490426
GO:0042578	phosphoric ester hydrolase activity	14/495	363/18639	0.0385674931129477	1.45224142248936	0.105658799778766	0.391810701490426
GO:0072542	protein phosphatase activator activity	2/495	21/18639	0.0952380952380952	3.58614718614719	0.10614791912888	0.391810701490426
GO:0016248	channel inhibitor activity	3/495	44/18639	0.0681818181818182	2.56735537190083	0.111137007836548	0.404280999521355
GO:0030020	extracellular matrix structural constituent conferring tensile strength	3/495	44/18639	0.0681818181818182	2.56735537190083	0.111137007836548	0.404280999521355
GO:0030547	signaling receptor inhibitor activity	3/495	44/18639	0.0681818181818182	2.56735537190083	0.111137007836548	0.404280999521355
GO:0008093	cytoskeletal anchor activity	2/495	22/18639	0.0909090909090909	3.42314049586777	0.114792616193624	0.411613523779993
GO:0030021	extracellular matrix structural constituent conferring compression resistance	2/495	22/18639	0.0909090909090909	3.42314049586777	0.114792616193624	0.411613523779993
GO:0061133	endopeptidase activator activity	2/495	22/18639	0.0909090909090909	3.42314049586777	0.114792616193624	0.411613523779993
GO:0097110	scaffold protein binding	4/495	70/18639	0.0571428571428571	2.15168831168831	0.11542031056021	0.411902814463687
GO:0004715	non-membrane spanning protein tyrosine kinase activity	3/495	45/18639	0.0666666666666667	2.51030303030303	0.116855762502611	0.41310980828388
GO:0141110	transporter inhibitor activity	3/495	45/18639	0.0666666666666667	2.51030303030303	0.116855762502611	0.41310980828388
GO:0004725	protein tyrosine phosphatase activity	5/495	98/18639	0.0510204081632653	1.92115027829314	0.119731437828211	0.421298003199266
GO:0004180	carboxypeptidase activity	3/495	46/18639	0.0652173913043478	2.45573122529644	0.122682148562917	0.429672827292449
GO:0043274	phospholipase binding	2/495	23/18639	0.0869565217391304	3.27430830039526	0.123609142745728	0.430915205960801
GO:0001784	phosphotyrosine residue binding	3/495	47/18639	0.0638297872340425	2.40348162475822	0.128612187051949	0.446209034453525
GO:0035591	signaling adaptor activity	6/495	129/18639	0.0465116279069767	1.75137420718816	0.129309473189696	0.446209034453525
GO:0015149	hexose transmembrane transporter activity	2/495	24/18639	0.0833333333333333	3.13787878787879	0.132582323065167	0.446209034453525
GO:0030552	cAMP binding	2/495	24/18639	0.0833333333333333	3.13787878787879	0.132582323065167	0.446209034453525
GO:0035035	histone acetyltransferase binding	2/495	24/18639	0.0833333333333333	3.13787878787879	0.132582323065167	0.446209034453525
GO:0055056	D-glucose transmembrane transporter activity	2/495	24/18639	0.0833333333333333	3.13787878787879	0.132582323065167	0.446209034453525
GO:0060229	lipase activator activity	2/495	24/18639	0.0833333333333333	3.13787878787879	0.132582323065167	0.446209034453525
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	6/495	130/18639	0.0461538461538462	1.7379020979021	0.132736817686042	0.446209034453525
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	3/495	48/18639	0.0625	2.35340909090909	0.134641881714671	0.446436571167776
GO:0044183	protein folding chaperone	4/495	75/18639	0.0533333333333333	2.00824242424242	0.138557666846426	0.446436571167776
GO:0005004	GPI-linked ephrin receptor activity	3/495	49/18639	0.0612244897959184	2.30538033395176	0.140767226724562	0.446436571167776
GO:0005008	hepatocyte growth factor receptor activity	3/495	49/18639	0.0612244897959184	2.30538033395176	0.140767226724562	0.446436571167776
GO:0005009	insulin receptor activity	3/495	49/18639	0.0612244897959184	2.30538033395176	0.140767226724562	0.446436571167776
GO:0005011	macrophage colony-stimulating factor receptor activity	3/495	49/18639	0.0612244897959184	2.30538033395176	0.140767226724562	0.446436571167776
GO:0005018	platelet-derived growth factor alpha-receptor activity	3/495	49/18639	0.0612244897959184	2.30538033395176	0.140767226724562	0.446436571167776
GO:0005020	stem cell factor receptor activity	3/495	49/18639	0.0612244897959184	2.30538033395176	0.140767226724562	0.446436571167776
GO:0008288	boss receptor activity	3/495	49/18639	0.0612244897959184	2.30538033395176	0.140767226724562	0.446436571167776
GO:0036332	placental growth factor receptor activity	3/495	49/18639	0.0612244897959184	2.30538033395176	0.140767226724562	0.446436571167776
GO:0038062	protein tyrosine kinase collagen receptor activity	3/495	49/18639	0.0612244897959184	2.30538033395176	0.140767226724562	0.446436571167776
GO:0060175	brain-derived neurotrophic factor receptor activity	3/495	49/18639	0.0612244897959184	2.30538033395176	0.140767226724562	0.446436571167776
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	2/495	25/18639	0.08	3.01236363636364	0.141697663358696	0.446436571167776
GO:0042974	nuclear retinoic acid receptor binding	2/495	25/18639	0.08	3.01236363636364	0.141697663358696	0.446436571167776
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	2/495	25/18639	0.08	3.01236363636364	0.141697663358696	0.446436571167776
GO:0017022	myosin binding	4/495	76/18639	0.0526315789473684	1.98181818181818	0.143393864484065	0.447475664379236
GO:0005007	fibroblast growth factor receptor activity	3/495	50/18639	0.06	2.25927272727273	0.146984213900762	0.447475664379236
GO:0005017	platelet-derived growth factor receptor activity	3/495	50/18639	0.06	2.25927272727273	0.146984213900762	0.447475664379236
GO:0005019	platelet-derived growth factor beta-receptor activity	3/495	50/18639	0.06	2.25927272727273	0.146984213900762	0.447475664379236
GO:0032813	tumor necrosis factor receptor superfamily binding	3/495	50/18639	0.06	2.25927272727273	0.146984213900762	0.447475664379236
GO:0004435	phosphatidylinositol phospholipase C activity	2/495	26/18639	0.0769230769230769	2.8965034965035	0.150941326364311	0.447475664379236
GO:0004529	DNA exonuclease activity	2/495	26/18639	0.0769230769230769	2.8965034965035	0.150941326364311	0.447475664379236
GO:0005160	transforming growth factor beta receptor binding	2/495	26/18639	0.0769230769230769	2.8965034965035	0.150941326364311	0.447475664379236
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	2/495	26/18639	0.0769230769230769	2.8965034965035	0.150941326364311	0.447475664379236
GO:0015145	monosaccharide transmembrane transporter activity	2/495	26/18639	0.0769230769230769	2.8965034965035	0.150941326364311	0.447475664379236
GO:0019865	immunoglobulin binding	2/495	26/18639	0.0769230769230769	2.8965034965035	0.150941326364311	0.447475664379236
GO:0030247	polysaccharide binding	2/495	26/18639	0.0769230769230769	2.8965034965035	0.150941326364311	0.447475664379236
GO:0030507	spectrin binding	2/495	26/18639	0.0769230769230769	2.8965034965035	0.150941326364311	0.447475664379236
GO:0050750	low-density lipoprotein particle receptor binding	2/495	26/18639	0.0769230769230769	2.8965034965035	0.150941326364311	0.447475664379236
GO:0070412	R-SMAD binding	2/495	26/18639	0.0769230769230769	2.8965034965035	0.150941326364311	0.447475664379236
GO:0005021	vascular endothelial growth factor receptor activity	3/495	51/18639	0.0588235294117647	2.21497326203209	0.153288839448112	0.450884750407923
GO:0005030	neurotrophin receptor activity	3/495	51/18639	0.0588235294117647	2.21497326203209	0.153288839448112	0.450884750407923
GO:0002020	protease binding	6/495	136/18639	0.0441176470588235	1.66122994652406	0.154182809386991	0.45174963217278
GO:0016758	hexosyltransferase activity	8/495	197/18639	0.0406091370558376	1.5291185971389	0.154859559271115	0.451973829965697
GO:0140297	DNA-binding transcription factor binding	17/495	488/18639	0.0348360655737705	1.31173621460507	0.155803392382231	0.452972797157606
GO:0016922	nuclear receptor binding	6/495	137/18639	0.0437956204379562	1.64910418049104	0.157898728841338	0.457299010836644
GO:0060589	nucleoside-triphosphatase regulator activity	17/495	490/18639	0.0346938775510204	1.30638218923933	0.159625507931862	0.45891932829354
GO:0030159	signaling receptor complex adaptor activity	3/495	52/18639	0.0576923076923077	2.17237762237762	0.159677110242905	0.45891932829354
GO:0004364	glutathione transferase activity	2/495	27/18639	0.0740740740740741	2.78922558922559	0.160300106819272	0.458958100512973
GO:0016829	lyase activity	8/495	200/18639	0.04	1.50618181818182	0.164099113017218	0.468055424628656
GO:0005003	ephrin receptor activity	3/495	53/18639	0.0566037735849057	2.13138936535163	0.166145049686228	0.468566376081385
GO:0005005	transmembrane-ephrin receptor activity	3/495	53/18639	0.0566037735849057	2.13138936535163	0.166145049686228	0.468566376081385
GO:0038064	collagen receptor activity	3/495	53/18639	0.0566037735849057	2.13138936535163	0.166145049686228	0.468566376081385
GO:0030971	receptor tyrosine kinase binding	4/495	81/18639	0.0493827160493827	1.85948372615039	0.168522743372989	0.473445703874856
GO:0051019	mitogen-activated protein kinase binding	2/495	28/18639	0.0714285714285714	2.68961038961039	0.169761407763893	0.473445703874856
GO:0051119	sugar transmembrane transporter activity	2/495	28/18639	0.0714285714285714	2.68961038961039	0.169761407763893	0.473445703874856
GO:0003714	transcription corepressor activity	8/495	204/18639	0.0392156862745098	1.47664884135472	0.176804151389675	0.490135696634369
GO:0020037	heme binding	6/495	142/18639	0.0422535211267606	1.5910371318822	0.177047688558497	0.490135696634369
GO:0003785	actin monomer binding	2/495	29/18639	0.0689655172413793	2.59686520376176	0.17931321765412	0.492784134648002
GO:0035250	UDP-galactosyltransferase activity	2/495	29/18639	0.0689655172413793	2.59686520376176	0.17931321765412	0.492784134648002
GO:0170055	lipid transmembrane transporter activity	3/495	56/18639	0.0535714285714286	2.01720779220779	0.185987473349886	0.509121507171062
GO:0005516	calmodulin binding	8/495	207/18639	0.0386473429951691	1.455248133509	0.186610273544772	0.509121507171062
GO:0048019	receptor antagonist activity	2/495	30/18639	0.0666666666666667	2.51030303030303	0.188944088256823	0.513627792264938
GO:0050660	flavin adenine dinucleotide binding	4/495	86/18639	0.0465116279069767	1.75137420718816	0.195064448219115	0.528358019816524
GO:0008081	phosphoric diester hydrolase activity	4/495	87/18639	0.0459770114942529	1.7312434691745	0.200521881970065	0.541193466392327
GO:0045309	protein phosphorylated amino acid binding	3/495	59/18639	0.0508474576271186	1.91463790446841	0.206406412002411	0.552553276854289
GO:0008378	galactosyltransferase activity	2/495	32/18639	0.0625	2.35340909090909	0.208399907870675	0.552553276854289
GO:0071813	lipoprotein particle binding	2/495	32/18639	0.0625	2.35340909090909	0.208399907870675	0.552553276854289
GO:0071814	protein-lipid complex binding	2/495	32/18639	0.0625	2.35340909090909	0.208399907870675	0.552553276854289
GO:0120015	sterol transfer activity	2/495	32/18639	0.0625	2.35340909090909	0.208399907870675	0.552553276854289
GO:0046906	tetrapyrrole binding	6/495	152/18639	0.0394736842105263	1.48636363636364	0.217917407740046	0.57450368926277
GO:0071889	14-3-3 protein binding	2/495	33/18639	0.0606060606060606	2.28209366391185	0.21820458848493	0.57450368926277
GO:0016836	hydro-lyase activity	3/495	61/18639	0.0491803278688525	1.85186289120715	0.220288861140383	0.57797042661571
GO:1901981	phosphatidylinositol phosphate binding	7/495	185/18639	0.0378378378378378	1.42476658476658	0.222292749713543	0.580821653632959
GO:0005506	iron ion binding	6/495	154/18639	0.038961038961039	1.46706021251476	0.226453323964156	0.580821653632959
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	2/495	34/18639	0.0588235294117647	2.21497326203209	0.228047753893397	0.580821653632959
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	2/495	34/18639	0.0588235294117647	2.21497326203209	0.228047753893397	0.580821653632959
GO:0090482	vitamin transmembrane transporter activity	2/495	34/18639	0.0588235294117647	2.21497326203209	0.228047753893397	0.580821653632959
GO:0030695	GTPase regulator activity	16/495	489/18639	0.032719836400818	1.23205056701989	0.230359061521078	0.580821653632959
GO:0003680	minor groove of adenine-thymine-rich DNA binding	1/495	10/18639	0.1	3.76545454545455	0.236031110241282	0.580821653632959
GO:0004862	cAMP-dependent protein kinase inhibitor activity	1/495	10/18639	0.1	3.76545454545455	0.236031110241282	0.580821653632959
GO:0005345	purine nucleobase transmembrane transporter activity	1/495	10/18639	0.1	3.76545454545455	0.236031110241282	0.580821653632959
GO:0005522	profilin binding	1/495	10/18639	0.1	3.76545454545455	0.236031110241282	0.580821653632959
GO:0005528	FK506 binding	1/495	10/18639	0.1	3.76545454545455	0.236031110241282	0.580821653632959
GO:0008297	single-stranded DNA exodeoxyribonuclease activity	1/495	10/18639	0.1	3.76545454545455	0.236031110241282	0.580821653632959
GO:0008401	retinoic acid 4-hydroxylase activity	1/495	10/18639	0.1	3.76545454545455	0.236031110241282	0.580821653632959
GO:0008641	ubiquitin-like modifier activating enzyme activity	1/495	10/18639	0.1	3.76545454545455	0.236031110241282	0.580821653632959
GO:0015187	glycine transmembrane transporter activity	1/495	10/18639	0.1	3.76545454545455	0.236031110241282	0.580821653632959
GO:0016175	superoxide-generating NAD(P)H oxidase activity	1/495	10/18639	0.1	3.76545454545455	0.236031110241282	0.580821653632959
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	1/495	10/18639	0.1	3.76545454545455	0.236031110241282	0.580821653632959
GO:0042975	peroxisome proliferator activated receptor binding	1/495	10/18639	0.1	3.76545454545455	0.236031110241282	0.580821653632959
GO:0140135	mechanosensitive monoatomic cation channel activity	1/495	10/18639	0.1	3.76545454545455	0.236031110241282	0.580821653632959
GO:0005154	epidermal growth factor receptor binding	2/495	35/18639	0.0571428571428571	2.15168831168831	0.237920466513591	0.5835638804063
GO:0004867	serine-type endopeptidase inhibitor activity	4/495	95/18639	0.0421052631578947	1.58545454545455	0.245654844245705	0.589859905456603
GO:0004190	aspartic-type endopeptidase activity	2/495	36/18639	0.0555555555555556	2.09191919191919	0.247814234519288	0.589859905456603
GO:0042826	histone deacetylase binding	5/495	127/18639	0.0393700787401575	1.48246241947029	0.24876738572719	0.589859905456603
GO:0004016	adenylate cyclase activity	1/495	11/18639	0.0909090909090909	3.42314049586777	0.256330890177433	0.589859905456603
GO:0005114	type II transforming growth factor beta receptor binding	1/495	11/18639	0.0909090909090909	3.42314049586777	0.256330890177433	0.589859905456603
GO:0008046	axon guidance receptor activity	1/495	11/18639	0.0909090909090909	3.42314049586777	0.256330890177433	0.589859905456603
GO:0008503	benzodiazepine receptor activity	1/495	11/18639	0.0909090909090909	3.42314049586777	0.256330890177433	0.589859905456603
GO:0010854	adenylate cyclase regulator activity	1/495	11/18639	0.0909090909090909	3.42314049586777	0.256330890177433	0.589859905456603
GO:0015205	nucleobase transmembrane transporter activity	1/495	11/18639	0.0909090909090909	3.42314049586777	0.256330890177433	0.589859905456603
GO:0015217	ADP transmembrane transporter activity	1/495	11/18639	0.0909090909090909	3.42314049586777	0.256330890177433	0.589859905456603
GO:0032404	mismatch repair complex binding	1/495	11/18639	0.0909090909090909	3.42314049586777	0.256330890177433	0.589859905456603
GO:0034511	U3 snoRNA binding	1/495	11/18639	0.0909090909090909	3.42314049586777	0.256330890177433	0.589859905456603
GO:0034713	type I transforming growth factor beta receptor binding	1/495	11/18639	0.0909090909090909	3.42314049586777	0.256330890177433	0.589859905456603
GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	1/495	11/18639	0.0909090909090909	3.42314049586777	0.256330890177433	0.589859905456603
GO:0045294	alpha-catenin binding	1/495	11/18639	0.0909090909090909	3.42314049586777	0.256330890177433	0.589859905456603
GO:0048407	platelet-derived growth factor binding	1/495	11/18639	0.0909090909090909	3.42314049586777	0.256330890177433	0.589859905456603
GO:0097493	structural molecule activity conferring elasticity	1/495	11/18639	0.0909090909090909	3.42314049586777	0.256330890177433	0.589859905456603
GO:0140537	transcription regulator activator activity	1/495	11/18639	0.0909090909090909	3.42314049586777	0.256330890177433	0.589859905456603
GO:1990948	ubiquitin ligase inhibitor activity	1/495	11/18639	0.0909090909090909	3.42314049586777	0.256330890177433	0.589859905456603
GO:0030280	structural constituent of skin epidermis	2/495	37/18639	0.0540540540540541	2.03538083538084	0.257720994548768	0.589859905456603
GO:0030551	cyclic nucleotide binding	2/495	37/18639	0.0540540540540541	2.03538083538084	0.257720994548768	0.589859905456603
GO:0070001	aspartic-type peptidase activity	2/495	37/18639	0.0540540540540541	2.03538083538084	0.257720994548768	0.589859905456603
GO:0000146	microfilament motor activity	2/495	38/18639	0.0526315789473684	1.98181818181818	0.267633095014119	0.590617979743547
GO:0005501	retinoid binding	2/495	38/18639	0.0526315789473684	1.98181818181818	0.267633095014119	0.590617979743547
GO:0019840	isoprenoid binding	2/495	38/18639	0.0526315789473684	1.98181818181818	0.267633095014119	0.590617979743547
GO:0031072	heat shock protein binding	5/495	131/18639	0.0381679389312977	1.43719639139486	0.268884892331981	0.590617979743547
GO:0030145	manganese ion binding	3/495	68/18639	0.0441176470588235	1.66122994652406	0.270124430768725	0.590617979743547
GO:0005179	hormone activity	5/495	132/18639	0.0378787878787879	1.4263085399449	0.27397013474787	0.590617979743547
GO:0004126	cytidine deaminase activity	1/495	12/18639	0.0833333333333333	3.13787878787879	0.276092335816373	0.590617979743547
GO:0004875	complement receptor activity	1/495	12/18639	0.0833333333333333	3.13787878787879	0.276092335816373	0.590617979743547
GO:0005095	GTPase inhibitor activity	1/495	12/18639	0.0833333333333333	3.13787878787879	0.276092335816373	0.590617979743547
GO:0005527	macrolide binding	1/495	12/18639	0.0833333333333333	3.13787878787879	0.276092335816373	0.590617979743547
GO:0008499	N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity	1/495	12/18639	0.0833333333333333	3.13787878787879	0.276092335816373	0.590617979743547
GO:0008603	cAMP-dependent protein kinase regulator activity	1/495	12/18639	0.0833333333333333	3.13787878787879	0.276092335816373	0.590617979743547
GO:0010853	cyclase activator activity	1/495	12/18639	0.0833333333333333	3.13787878787879	0.276092335816373	0.590617979743547
GO:0015166	polyol transmembrane transporter activity	1/495	12/18639	0.0833333333333333	3.13787878787879	0.276092335816373	0.590617979743547
GO:0015269	calcium-activated potassium channel activity	1/495	12/18639	0.0833333333333333	3.13787878787879	0.276092335816373	0.590617979743547
GO:0031543	peptidyl-proline dioxygenase activity	1/495	12/18639	0.0833333333333333	3.13787878787879	0.276092335816373	0.590617979743547
GO:0035259	nuclear glucocorticoid receptor binding	1/495	12/18639	0.0833333333333333	3.13787878787879	0.276092335816373	0.590617979743547
GO:0070008	serine-type exopeptidase activity	1/495	12/18639	0.0833333333333333	3.13787878787879	0.276092335816373	0.590617979743547
GO:0097371	MDM2/MDM4 family protein binding	1/495	12/18639	0.0833333333333333	3.13787878787879	0.276092335816373	0.590617979743547
GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	1/495	12/18639	0.0833333333333333	3.13787878787879	0.276092335816373	0.590617979743547
GO:0140822	NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity	1/495	12/18639	0.0833333333333333	3.13787878787879	0.276092335816373	0.590617979743547
GO:0140844	NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity	1/495	12/18639	0.0833333333333333	3.13787878787879	0.276092335816373	0.590617979743547
GO:0140867	NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity	1/495	12/18639	0.0833333333333333	3.13787878787879	0.276092335816373	0.590617979743547
GO:0016776	phosphotransferase activity, phosphate group as acceptor	2/495	39/18639	0.0512820512820513	1.93100233100233	0.277543279991982	0.592039914543802
GO:0008028	monocarboxylic acid transmembrane transporter activity	3/495	70/18639	0.0428571428571429	1.61376623376623	0.284607647809772	0.604302338334536
GO:0015144	carbohydrate transmembrane transporter activity	2/495	40/18639	0.05	1.88272727272727	0.28744467367672	0.604302338334536
GO:0071855	neuropeptide receptor binding	2/495	40/18639	0.05	1.88272727272727	0.28744467367672	0.604302338334536
GO:0140662	ATP-dependent protein folding chaperone	2/495	40/18639	0.05	1.88272727272727	0.28744467367672	0.604302338334536
GO:0004722	protein serine/threonine phosphatase activity	4/495	103/18639	0.0388349514563107	1.46231244483672	0.292736152594578	0.604302338334536
GO:0016779	nucleotidyltransferase activity	5/495	136/18639	0.0367647058823529	1.38435828877005	0.29450047808858	0.604302338334536
GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	1/495	13/18639	0.0769230769230769	2.8965034965035	0.295329695228565	0.604302338334536
GO:0004465	lipoprotein lipase activity	1/495	13/18639	0.0769230769230769	2.8965034965035	0.295329695228565	0.604302338334536
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	1/495	13/18639	0.0769230769230769	2.8965034965035	0.295329695228565	0.604302338334536
GO:0005338	nucleotide-sugar transmembrane transporter activity	1/495	13/18639	0.0769230769230769	2.8965034965035	0.295329695228565	0.604302338334536
GO:0019855	calcium channel inhibitor activity	1/495	13/18639	0.0769230769230769	2.8965034965035	0.295329695228565	0.604302338334536
GO:0035325	Toll-like receptor binding	1/495	13/18639	0.0769230769230769	2.8965034965035	0.295329695228565	0.604302338334536
GO:0039706	co-receptor binding	1/495	13/18639	0.0769230769230769	2.8965034965035	0.295329695228565	0.604302338334536
GO:0043560	insulin receptor substrate binding	1/495	13/18639	0.0769230769230769	2.8965034965035	0.295329695228565	0.604302338334536
GO:0070700	BMP receptor binding	1/495	13/18639	0.0769230769230769	2.8965034965035	0.295329695228565	0.604302338334536
GO:0017080	sodium channel regulator activity	2/495	41/18639	0.0487804878048781	1.83680709534368	0.297330765377589	0.605108287376552
GO:0042287	MHC protein binding	2/495	41/18639	0.0487804878048781	1.83680709534368	0.297330765377589	0.605108287376552
GO:0016791	phosphatase activity	9/495	273/18639	0.032967032967033	1.24135864135864	0.301893985907185	0.612739006436955
GO:0042056	chemoattractant activity	2/495	42/18639	0.0476190476190476	1.79307359307359	0.307195395042088	0.620386394921105
GO:0008201	heparin binding	6/495	172/18639	0.0348837209302326	1.31353065539112	0.307309595359326	0.620386394921105
GO:0004065	arylsulfatase activity	1/495	14/18639	0.0714285714285714	2.68961038961039	0.31405684012612	0.625530796664345
GO:0005161	platelet-derived growth factor receptor binding	1/495	14/18639	0.0714285714285714	2.68961038961039	0.31405684012612	0.625530796664345
GO:0005347	ATP transmembrane transporter activity	1/495	14/18639	0.0714285714285714	2.68961038961039	0.31405684012612	0.625530796664345
GO:0008494	translation activator activity	1/495	14/18639	0.0714285714285714	2.68961038961039	0.31405684012612	0.625530796664345
GO:0048156	tau protein binding	2/495	43/18639	0.0465116279069767	1.75137420718816	0.31703273928819	0.625530796664345
GO:0003725	double-stranded RNA binding	3/495	75/18639	0.04	1.50618181818182	0.32103566063732	0.625530796664345
GO:0003735	structural constituent of ribosome	6/495	175/18639	0.0342857142857143	1.29101298701299	0.321300135247794	0.625530796664345
GO:0001046	core promoter sequence-specific DNA binding	2/495	44/18639	0.0454545454545455	1.71157024793388	0.326837297928745	0.625530796664345
GO:0019205	nucleobase-containing compound kinase activity	2/495	44/18639	0.0454545454545455	1.71157024793388	0.326837297928745	0.625530796664345
GO:0004620	phospholipase activity	4/495	109/18639	0.036697247706422	1.38181818181818	0.32877825620961	0.625530796664345
GO:0004089	carbonate dehydratase activity	1/495	15/18639	0.0666666666666667	2.51030303030303	0.332287275784513	0.625530796664345
GO:0004129	cytochrome-c oxidase activity	1/495	15/18639	0.0666666666666667	2.51030303030303	0.332287275784513	0.625530796664345
GO:0005041	low-density lipoprotein particle receptor activity	1/495	15/18639	0.0666666666666667	2.51030303030303	0.332287275784513	0.625530796664345
GO:0005402	carbohydrate:monoatomic cation symporter activity	1/495	15/18639	0.0666666666666667	2.51030303030303	0.332287275784513	0.625530796664345
GO:0015929	hexosaminidase activity	1/495	15/18639	0.0666666666666667	2.51030303030303	0.332287275784513	0.625530796664345
GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	1/495	15/18639	0.0666666666666667	2.51030303030303	0.332287275784513	0.625530796664345
GO:0016846	carbon-sulfur lyase activity	1/495	15/18639	0.0666666666666667	2.51030303030303	0.332287275784513	0.625530796664345
GO:0017081	chloride channel regulator activity	1/495	15/18639	0.0666666666666667	2.51030303030303	0.332287275784513	0.625530796664345
GO:0030553	cGMP binding	1/495	15/18639	0.0666666666666667	2.51030303030303	0.332287275784513	0.625530796664345
GO:0031005	filamin binding	1/495	15/18639	0.0666666666666667	2.51030303030303	0.332287275784513	0.625530796664345
GO:0031386	protein tag activity	1/495	15/18639	0.0666666666666667	2.51030303030303	0.332287275784513	0.625530796664345
GO:0033130	acetylcholine receptor binding	1/495	15/18639	0.0666666666666667	2.51030303030303	0.332287275784513	0.625530796664345
GO:0048531	beta-1,3-galactosyltransferase activity	1/495	15/18639	0.0666666666666667	2.51030303030303	0.332287275784513	0.625530796664345
GO:0055105	ubiquitin-protein transferase inhibitor activity	1/495	15/18639	0.0666666666666667	2.51030303030303	0.332287275784513	0.625530796664345
GO:0061578	K63-linked deubiquitinase activity	1/495	15/18639	0.0666666666666667	2.51030303030303	0.332287275784513	0.625530796664345
GO:0120283	protein serine/threonine kinase binding	1/495	15/18639	0.0666666666666667	2.51030303030303	0.332287275784513	0.625530796664345
GO:0141047	molecular tag activity	1/495	15/18639	0.0666666666666667	2.51030303030303	0.332287275784513	0.625530796664345
GO:0004222	metalloendopeptidase activity	4/495	110/18639	0.0363636363636364	1.36925619834711	0.334816894395405	0.628721001196359
GO:0140303	intramembrane lipid transporter activity	2/495	45/18639	0.0444444444444444	1.67353535353535	0.336603880971821	0.630504284506919
GO:0005159	insulin-like growth factor receptor binding	1/495	16/18639	0.0625	2.35340909090909	0.350034150703255	0.644778539236753
GO:0005324	long-chain fatty acid transmembrane transporter activity	1/495	16/18639	0.0625	2.35340909090909	0.350034150703255	0.644778539236753
GO:0016675	oxidoreductase activity, acting on a heme group of donors	1/495	16/18639	0.0625	2.35340909090909	0.350034150703255	0.644778539236753
GO:0019841	retinol binding	1/495	16/18639	0.0625	2.35340909090909	0.350034150703255	0.644778539236753
GO:0022858	alanine transmembrane transporter activity	1/495	16/18639	0.0625	2.35340909090909	0.350034150703255	0.644778539236753
GO:0140328	floppase activity	1/495	16/18639	0.0625	2.35340909090909	0.350034150703255	0.644778539236753
GO:0046332	SMAD binding	3/495	79/18639	0.0379746835443038	1.42991944764097	0.350218356637227	0.644778539236753
GO:0033192	calmodulin-dependent protein phosphatase activity	3/495	81/18639	0.037037037037037	1.39461279461279	0.364766181980797	0.650787365429
GO:0140791	histone H2AXS140 phosphatase activity	3/495	81/18639	0.037037037037037	1.39461279461279	0.364766181980797	0.650787365429
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	3/495	81/18639	0.037037037037037	1.39461279461279	0.364766181980797	0.650787365429
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	3/495	81/18639	0.037037037037037	1.39461279461279	0.364766181980797	0.650787365429
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	3/495	81/18639	0.037037037037037	1.39461279461279	0.364766181980797	0.650787365429
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	3/495	81/18639	0.037037037037037	1.39461279461279	0.364766181980797	0.650787365429
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	3/495	81/18639	0.037037037037037	1.39461279461279	0.364766181980797	0.650787365429
GO:1990439	MAP kinase serine/threonine phosphatase activity	3/495	81/18639	0.037037037037037	1.39461279461279	0.364766181980797	0.650787365429
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	1/495	17/18639	0.0588235294117647	2.21497326203209	0.367310266012384	0.650787365429
GO:0005092	GDP-dissociation inhibitor activity	1/495	17/18639	0.0588235294117647	2.21497326203209	0.367310266012384	0.650787365429
GO:0008484	sulfuric ester hydrolase activity	1/495	17/18639	0.0588235294117647	2.21497326203209	0.367310266012384	0.650787365429
GO:0030169	low-density lipoprotein particle binding	1/495	17/18639	0.0588235294117647	2.21497326203209	0.367310266012384	0.650787365429
GO:0030548	acetylcholine receptor regulator activity	1/495	17/18639	0.0588235294117647	2.21497326203209	0.367310266012384	0.650787365429
GO:0036041	long-chain fatty acid binding	1/495	17/18639	0.0588235294117647	2.21497326203209	0.367310266012384	0.650787365429
GO:0051787	misfolded protein binding	1/495	17/18639	0.0588235294117647	2.21497326203209	0.367310266012384	0.650787365429
GO:0070492	oligosaccharide binding	1/495	17/18639	0.0588235294117647	2.21497326203209	0.367310266012384	0.650787365429
GO:0003713	transcription coactivator activity	8/495	256/18639	0.03125	1.17670454545455	0.370658619544368	0.654513394299974
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	3/495	82/18639	0.0365853658536585	1.37760532150776	0.372020893440091	0.654513394299974
GO:0033549	MAP kinase phosphatase activity	3/495	82/18639	0.0365853658536585	1.37760532150776	0.372020893440091	0.654513394299974
GO:0035254	glutamate receptor binding	2/495	49/18639	0.0408163265306122	1.53692022263451	0.375196824301771	0.658562258040172
GO:0019208	phosphatase regulator activity	4/495	117/18639	0.0341880341880342	1.28733488733489	0.377137822525979	0.659871023577598
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	3/495	83/18639	0.036144578313253	1.36100766703176	0.379259820614472	0.659871023577598
GO:0003774	cytoskeletal motor activity	5/495	153/18639	0.0326797385620915	1.23054070112894	0.383703543017364	0.659871023577598
GO:0008525	phosphatidylcholine transporter activity	1/495	18/18639	0.0555555555555556	2.09191919191919	0.384128084631429	0.659871023577598
GO:0017128	phospholipid scramblase activity	1/495	18/18639	0.0555555555555556	2.09191919191919	0.384128084631429	0.659871023577598
GO:0030228	lipoprotein particle receptor activity	1/495	18/18639	0.0555555555555556	2.09191919191919	0.384128084631429	0.659871023577598
GO:0031690	adrenergic receptor binding	1/495	18/18639	0.0555555555555556	2.09191919191919	0.384128084631429	0.659871023577598
GO:0034185	apolipoprotein binding	1/495	18/18639	0.0555555555555556	2.09191919191919	0.384128084631429	0.659871023577598
GO:0099602	neurotransmitter receptor regulator activity	1/495	18/18639	0.0555555555555556	2.09191919191919	0.384128084631429	0.659871023577598
GO:0015605	organophosphate ester transmembrane transporter activity	2/495	50/18639	0.04	1.50618181818182	0.38470568306848	0.659871023577598
GO:0017018	myosin phosphatase activity	3/495	84/18639	0.0357142857142857	1.34480519480519	0.386480812247189	0.661409208232122
GO:0046982	protein heterodimerization activity	11/495	369/18639	0.029810298102981	1.12249322493225	0.391267620101209	0.665483752889681
GO:0030544	Hsp70 protein binding	2/495	51/18639	0.0392156862745098	1.47664884135472	0.394151268522373	0.665483752889681
GO:0003756	protein disulfide isomerase activity	1/495	19/18639	0.0526315789473684	1.98181818181818	0.400499740187385	0.665483752889681
GO:0005229	intracellularly calcium-gated chloride channel activity	1/495	19/18639	0.0526315789473684	1.98181818181818	0.400499740187385	0.665483752889681
GO:0005346	purine ribonucleotide transmembrane transporter activity	1/495	19/18639	0.0526315789473684	1.98181818181818	0.400499740187385	0.665483752889681
GO:0008381	mechanosensitive monoatomic ion channel activity	1/495	19/18639	0.0526315789473684	1.98181818181818	0.400499740187385	0.665483752889681
GO:0015245	fatty acid transmembrane transporter activity	1/495	19/18639	0.0526315789473684	1.98181818181818	0.400499740187385	0.665483752889681
GO:0015355	secondary active monocarboxylate transmembrane transporter activity	1/495	19/18639	0.0526315789473684	1.98181818181818	0.400499740187385	0.665483752889681
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	1/495	19/18639	0.0526315789473684	1.98181818181818	0.400499740187385	0.665483752889681
GO:0016918	retinal binding	1/495	19/18639	0.0526315789473684	1.98181818181818	0.400499740187385	0.665483752889681
GO:0042834	peptidoglycan binding	1/495	19/18639	0.0526315789473684	1.98181818181818	0.400499740187385	0.665483752889681
GO:0141147	intracellularly calcium-gated channel activity	1/495	19/18639	0.0526315789473684	1.98181818181818	0.400499740187385	0.665483752889681
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	3/495	86/18639	0.0348837209302326	1.31353065539112	0.400860725417045	0.665483752889681
GO:0003697	single-stranded DNA binding	4/495	121/18639	0.0330578512396694	1.24477836213373	0.401234560175186	0.665483752889681
GO:0000287	magnesium ion binding	7/495	230/18639	0.0304347826086957	1.14600790513834	0.411371031174981	0.677272344299303
GO:0016860	intramolecular oxidoreductase activity	2/495	53/18639	0.0377358490566038	1.42092624356775	0.41283945780129	0.677272344299303
GO:0051018	protein kinase A binding	2/495	53/18639	0.0377358490566038	1.42092624356775	0.41283945780129	0.677272344299303
GO:1901505	carbohydrate derivative transmembrane transporter activity	2/495	53/18639	0.0377358490566038	1.42092624356775	0.41283945780129	0.677272344299303
GO:0001972	retinoic acid binding	1/495	20/18639	0.05	1.88272727272727	0.416437045697978	0.677272344299303
GO:0010851	cyclase regulator activity	1/495	20/18639	0.05	1.88272727272727	0.416437045697978	0.677272344299303
GO:0031418	L-ascorbic acid binding	1/495	20/18639	0.05	1.88272727272727	0.416437045697978	0.677272344299303
GO:0042288	MHC class I protein binding	1/495	20/18639	0.05	1.88272727272727	0.416437045697978	0.677272344299303
GO:0052745	inositol phosphate phosphatase activity	1/495	20/18639	0.05	1.88272727272727	0.416437045697978	0.677272344299303
GO:0003925	G protein activity	2/495	54/18639	0.037037037037037	1.39461279461279	0.422076025288036	0.684963894486835
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	1/495	21/18639	0.0476190476190476	1.79307359307359	0.431951502026433	0.690572146551813
GO:0008373	sialyltransferase activity	1/495	21/18639	0.0476190476190476	1.79307359307359	0.431951502026433	0.690572146551813
GO:0009975	cyclase activity	1/495	21/18639	0.0476190476190476	1.79307359307359	0.431951502026433	0.690572146551813
GO:0015125	bile acid transmembrane transporter activity	1/495	21/18639	0.0476190476190476	1.79307359307359	0.431951502026433	0.690572146551813
GO:0019200	carbohydrate kinase activity	1/495	21/18639	0.0476190476190476	1.79307359307359	0.431951502026433	0.690572146551813
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	1/495	21/18639	0.0476190476190476	1.79307359307359	0.431951502026433	0.690572146551813
GO:0070182	DNA polymerase binding	1/495	21/18639	0.0476190476190476	1.79307359307359	0.431951502026433	0.690572146551813
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	4/495	128/18639	0.03125	1.17670454545455	0.44295034694468	0.705727237953087
GO:0003712	transcription coregulator activity	14/495	495/18639	0.0282828282828283	1.06497704315886	0.443366988619405	0.705727237953087
GO:0008970	phospholipase A1 activity	1/495	22/18639	0.0454545454545455	1.71157024793388	0.447054306113709	0.705727237953087
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	1/495	22/18639	0.0454545454545455	1.71157024793388	0.447054306113709	0.705727237953087
GO:0031683	G-protein beta/gamma-subunit complex binding	1/495	22/18639	0.0454545454545455	1.71157024793388	0.447054306113709	0.705727237953087
GO:0033691	sialic acid binding	1/495	22/18639	0.0454545454545455	1.71157024793388	0.447054306113709	0.705727237953087
GO:0015932	nucleobase-containing compound transmembrane transporter activity	2/495	57/18639	0.0350877192982456	1.32121212121212	0.449323669685752	0.707825780906634
GO:0051219	phosphoprotein binding	3/495	93/18639	0.032258064516129	1.21466275659824	0.450341023790859	0.707947371429055
GO:0016298	lipase activity	4/495	130/18639	0.0307692307692308	1.1586013986014	0.45471757003329	0.711048135628908
GO:0042562	hormone binding	3/495	94/18639	0.0319148936170213	1.20174081237911	0.457279054322487	0.711048135628908
GO:0008408	3'-5' exonuclease activity	2/495	58/18639	0.0344827586206897	1.29843260188088	0.458244429106775	0.711048135628908
GO:0000295	adenine nucleotide transmembrane transporter activity	1/495	23/18639	0.0434782608695652	1.63715415019763	0.461756358994072	0.711048135628908
GO:0005283	amino acid:sodium symporter activity	1/495	23/18639	0.0434782608695652	1.63715415019763	0.461756358994072	0.711048135628908
GO:0016849	phosphorus-oxygen lyase activity	1/495	23/18639	0.0434782608695652	1.63715415019763	0.461756358994072	0.711048135628908
GO:0017134	fibroblast growth factor binding	1/495	23/18639	0.0434782608695652	1.63715415019763	0.461756358994072	0.711048135628908
GO:0031681	G-protein beta-subunit binding	1/495	23/18639	0.0434782608695652	1.63715415019763	0.461756358994072	0.711048135628908
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	1/495	23/18639	0.0434782608695652	1.63715415019763	0.461756358994072	0.711048135628908
GO:0140103	catalytic activity, acting on a glycoprotein	1/495	23/18639	0.0434782608695652	1.63715415019763	0.461756358994072	0.711048135628908
GO:0001786	phosphatidylserine binding	2/495	59/18639	0.0338983050847458	1.27642526964561	0.46708085075956	0.712297853121365
GO:0004879	nuclear receptor activity	2/495	59/18639	0.0338983050847458	1.27642526964561	0.46708085075956	0.712297853121365
GO:0031593	polyubiquitin modification-dependent protein binding	2/495	59/18639	0.0338983050847458	1.27642526964561	0.46708085075956	0.712297853121365
GO:0070888	E-box binding	2/495	59/18639	0.0338983050847458	1.27642526964561	0.46708085075956	0.712297853121365
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	2/495	60/18639	0.0333333333333333	1.25515151515152	0.475831117219231	0.712297853121365
GO:0098531	ligand-modulated transcription factor activity	2/495	60/18639	0.0333333333333333	1.25515151515152	0.475831117219231	0.712297853121365
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	1/495	24/18639	0.0416666666666667	1.56893939393939	0.476068273599677	0.712297853121365
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	1/495	24/18639	0.0416666666666667	1.56893939393939	0.476068273599677	0.712297853121365
GO:0004806	triacylglycerol lipase activity	1/495	24/18639	0.0416666666666667	1.56893939393939	0.476068273599677	0.712297853121365
GO:0015295	solute:proton symporter activity	1/495	24/18639	0.0416666666666667	1.56893939393939	0.476068273599677	0.712297853121365
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	1/495	24/18639	0.0416666666666667	1.56893939393939	0.476068273599677	0.712297853121365
GO:0050431	transforming growth factor beta binding	1/495	24/18639	0.0416666666666667	1.56893939393939	0.476068273599677	0.712297853121365
GO:0050699	WW domain binding	1/495	24/18639	0.0416666666666667	1.56893939393939	0.476068273599677	0.712297853121365
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	1/495	24/18639	0.0416666666666667	1.56893939393939	0.476068273599677	0.712297853121365
GO:0140996	histone H3 kinase activity	10/495	357/18639	0.0280112044817927	1.05474917239623	0.477112166319312	0.712297853121365
GO:0035091	phosphatidylinositol binding	8/495	284/18639	0.028169014084507	1.0606914212548	0.483191818897704	0.712297853121365
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	2/495	61/18639	0.0327868852459016	1.23457526080477	0.484493566577836	0.712297853121365
GO:0033218	amide binding	7/495	247/18639	0.0283400809716599	1.06713286713287	0.484589166354528	0.712297853121365
GO:0044389	ubiquitin-like protein ligase binding	9/495	322/18639	0.0279503105590062	1.05245623941276	0.485606293019527	0.712297853121365
GO:0035173	histone kinase activity	10/495	360/18639	0.0277777777777778	1.0459595959596	0.487698939971246	0.712297853121365
GO:0003707	nuclear steroid receptor activity	1/495	25/18639	0.04	1.50618181818182	0.490000382359717	0.712297853121365
GO:0005251	delayed rectifier potassium channel activity	1/495	25/18639	0.04	1.50618181818182	0.490000382359717	0.712297853121365
GO:0015271	outward rectifier potassium channel activity	1/495	25/18639	0.04	1.50618181818182	0.490000382359717	0.712297853121365
GO:0015662	P-type ion transporter activity	1/495	25/18639	0.04	1.50618181818182	0.490000382359717	0.712297853121365
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	1/495	25/18639	0.04	1.50618181818182	0.490000382359717	0.712297853121365
GO:0019706	protein-cysteine S-palmitoyltransferase activity	1/495	25/18639	0.04	1.50618181818182	0.490000382359717	0.712297853121365
GO:0019707	protein-cysteine S-acyltransferase activity	1/495	25/18639	0.04	1.50618181818182	0.490000382359717	0.712297853121365
GO:0120020	cholesterol transfer activity	1/495	25/18639	0.04	1.50618181818182	0.490000382359717	0.712297853121365
GO:0140358	P-type transmembrane transporter activity	1/495	25/18639	0.04	1.50618181818182	0.490000382359717	0.712297853121365
GO:0043130	ubiquitin binding	3/495	100/18639	0.03	1.12963636363636	0.498078877939523	0.722252850825617
GO:0004112	cyclic-nucleotide phosphodiesterase activity	1/495	26/18639	0.0384615384615385	1.44825174825175	0.503562744599534	0.722252850825617
GO:0005112	Notch binding	1/495	26/18639	0.0384615384615385	1.44825174825175	0.503562744599534	0.722252850825617
GO:0005227	calcium-activated cation channel activity	1/495	26/18639	0.0384615384615385	1.44825174825175	0.503562744599534	0.722252850825617
GO:0015216	purine nucleotide transmembrane transporter activity	1/495	26/18639	0.0384615384615385	1.44825174825175	0.503562744599534	0.722252850825617
GO:0034237	protein kinase A regulatory subunit binding	1/495	26/18639	0.0384615384615385	1.44825174825175	0.503562744599534	0.722252850825617
GO:0050681	nuclear androgen receptor binding	1/495	26/18639	0.0384615384615385	1.44825174825175	0.503562744599534	0.722252850825617
GO:0070851	growth factor receptor binding	4/495	139/18639	0.0287769784172662	1.08358404185742	0.506534985094786	0.725134683985502
GO:0004536	DNA nuclease activity	2/495	64/18639	0.03125	1.17670454545455	0.509939581604072	0.728623349047185
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	1/495	27/18639	0.037037037037037	1.39461279461279	0.516765153744928	0.736977577215778
GO:0120013	lipid transfer activity	2/495	65/18639	0.0307692307692308	1.1586013986014	0.518237015984354	0.737679533149752
GO:0005242	inward rectifier potassium channel activity	1/495	28/18639	0.0357142857142857	1.34480519480519	0.529617144336818	0.751039001291194
GO:0019789	SUMO transferase activity	1/495	28/18639	0.0357142857142857	1.34480519480519	0.529617144336818	0.751039001291194
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	2/495	67/18639	0.0298507462686567	1.12401628222524	0.53454893407549	0.755173814699593
GO:0004181	metallocarboxypeptidase activity	1/495	29/18639	0.0344827586206897	1.29843260188088	0.5421279988612	0.755173814699593
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	1/495	29/18639	0.0344827586206897	1.29843260188088	0.5421279988612	0.755173814699593
GO:0005416	amino acid:monoatomic cation symporter activity	1/495	29/18639	0.0344827586206897	1.29843260188088	0.5421279988612	0.755173814699593
GO:0016417	S-acyltransferase activity	1/495	29/18639	0.0344827586206897	1.29843260188088	0.5421279988612	0.755173814699593
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	1/495	29/18639	0.0344827586206897	1.29843260188088	0.5421279988612	0.755173814699593
GO:0051861	glycolipid binding	1/495	29/18639	0.0344827586206897	1.29843260188088	0.5421279988612	0.755173814699593
GO:0097472	cyclin-dependent protein kinase activity	1/495	29/18639	0.0344827586206897	1.29843260188088	0.5421279988612	0.755173814699593
GO:0005548	phospholipid transporter activity	2/495	68/18639	0.0294117647058824	1.10748663101604	0.542561797812058	0.755173814699593
GO:1990841	promoter-specific chromatin binding	2/495	68/18639	0.0294117647058824	1.10748663101604	0.542561797812058	0.755173814699593
GO:0019888	protein phosphatase regulator activity	3/495	107/18639	0.0280373831775701	1.05573491928632	0.543638307196484	0.755276098374451
GO:0002039	p53 binding	2/495	69/18639	0.0289855072463768	1.09143610013175	0.550478366047414	0.75614671388163
GO:0031625	ubiquitin protein ligase binding	8/495	302/18639	0.0264900662251656	0.997471402769416	0.552928128818218	0.75614671388163
GO:0001965	G-protein alpha-subunit binding	1/495	30/18639	0.0333333333333333	1.25515151515152	0.554306754399283	0.75614671388163
GO:0015215	nucleotide transmembrane transporter activity	1/495	30/18639	0.0333333333333333	1.25515151515152	0.554306754399283	0.75614671388163
GO:0016769	transferase activity, transferring nitrogenous groups	1/495	30/18639	0.0333333333333333	1.25515151515152	0.554306754399283	0.75614671388163
GO:0022839	monoatomic ion-gated channel activity	1/495	30/18639	0.0333333333333333	1.25515151515152	0.554306754399283	0.75614671388163
GO:0031210	phosphatidylcholine binding	1/495	30/18639	0.0333333333333333	1.25515151515152	0.554306754399283	0.75614671388163
GO:0033612	receptor serine/threonine kinase binding	1/495	30/18639	0.0333333333333333	1.25515151515152	0.554306754399283	0.75614671388163
GO:0051721	protein phosphatase 2A binding	1/495	30/18639	0.0333333333333333	1.25515151515152	0.554306754399283	0.75614671388163
GO:0070566	adenylyltransferase activity	1/495	30/18639	0.0333333333333333	1.25515151515152	0.554306754399283	0.75614671388163
GO:0008234	cysteine-type peptidase activity	5/495	187/18639	0.0267379679144385	1.0068060281964	0.556704569017386	0.756676065830491
GO:0031406	carboxylic acid binding	5/495	187/18639	0.0267379679144385	1.0068060281964	0.556704569017386	0.756676065830491
GO:0005543	phospholipid binding	13/495	497/18639	0.0261569416498994	0.98492774830803	0.562078724277594	0.762604106992843
GO:0008327	methyl-CpG binding	1/495	31/18639	0.032258064516129	1.21466275659824	0.56616220910251	0.764047907223371
GO:0017147	Wnt-protein binding	1/495	31/18639	0.032258064516129	1.21466275659824	0.56616220910251	0.764047907223371
GO:0043177	organic acid binding	5/495	189/18639	0.0264550264550265	0.996151996151996	0.566186895392618	0.764047907223371
GO:1902936	phosphatidylinositol bisphosphate binding	3/495	111/18639	0.027027027027027	1.01769041769042	0.568570671518027	0.765892156803353
GO:0030515	snoRNA binding	1/495	32/18639	0.03125	1.17670454545455	0.577702928497085	0.772664840423277
GO:0042910	xenobiotic transmembrane transporter activity	1/495	32/18639	0.03125	1.17670454545455	0.577702928497085	0.772664840423277
GO:0043425	bHLH transcription factor binding	1/495	32/18639	0.03125	1.17670454545455	0.577702928497085	0.772664840423277
GO:0051059	NF-kappaB binding	1/495	32/18639	0.03125	1.17670454545455	0.577702928497085	0.772664840423277
GO:0030296	protein tyrosine kinase activator activity	1/495	33/18639	0.0303030303030303	1.14104683195592	0.588937251622465	0.786293883815099
GO:0017124	SH3 domain binding	3/495	115/18639	0.0260869565217391	0.982292490118577	0.59264786242633	0.789847505145179
GO:0019003	GDP binding	2/495	75/18639	0.0266666666666667	1.00412121212121	0.59593151524198	0.792820549429701
GO:1901681	sulfur compound binding	7/495	275/18639	0.0254545454545455	0.958479338842975	0.59828591873192	0.793473415641458
GO:0015294	solute:monoatomic cation symporter activity	3/495	116/18639	0.0258620689655172	0.973824451410658	0.598529747787979	0.793473415641458
GO:0141003	histone H2AX kinase activity	9/495	354/18639	0.0254237288135593	0.957318952234206	0.599956833244003	0.793967478792152
GO:0000175	3'-5'-RNA exonuclease activity	1/495	35/18639	0.0285714285714286	1.07584415584416	0.61051896849333	0.805115207137438
GO:0005343	organic acid:sodium symporter activity	1/495	35/18639	0.0285714285714286	1.07584415584416	0.61051896849333	0.805115207137438
GO:0004869	cysteine-type endopeptidase inhibitor activity	1/495	36/18639	0.0277777777777778	1.0459595959596	0.620881960892588	0.808267072545341
GO:0005484	SNAP receptor activity	1/495	36/18639	0.0277777777777778	1.0459595959596	0.620881960892588	0.808267072545341
GO:0016409	palmitoyltransferase activity	1/495	36/18639	0.0277777777777778	1.0459595959596	0.620881960892588	0.808267072545341
GO:0055106	ubiquitin-protein transferase regulator activity	1/495	36/18639	0.0277777777777778	1.0459595959596	0.620881960892588	0.808267072545341
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	1/495	36/18639	0.0277777777777778	1.0459595959596	0.620881960892588	0.808267072545341
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	1/495	36/18639	0.0277777777777778	1.0459595959596	0.620881960892588	0.808267072545341
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	1/495	36/18639	0.0277777777777778	1.0459595959596	0.620881960892588	0.808267072545341
GO:0032182	ubiquitin-like protein binding	3/495	120/18639	0.025	0.941363636363636	0.621496195224107	0.808267072545341
GO:0015370	solute:sodium symporter activity	2/495	79/18639	0.0253164556962025	0.953279631760644	0.624271997656599	0.809082296446504
GO:0033293	monocarboxylic acid binding	2/495	79/18639	0.0253164556962025	0.953279631760644	0.624271997656599	0.809082296446504
GO:0051082	unfolded protein binding	3/495	121/18639	0.0247933884297521	0.933583771600301	0.627096067301622	0.811345942745913
GO:0022829	wide pore channel activity	1/495	37/18639	0.027027027027027	1.01769041769042	0.63096976551325	0.814957518750389
GO:0008528	G protein-coupled peptide receptor activity	3/495	122/18639	0.0245901639344262	0.925931445603577	0.632638772778456	0.815714034079071
GO:0005109	frizzled binding	1/495	38/18639	0.0263157894736842	0.990909090909091	0.64078967552674	0.822001065880128
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	1/495	38/18639	0.0263157894736842	0.990909090909091	0.64078967552674	0.822001065880128
GO:0043531	ADP binding	1/495	38/18639	0.0263157894736842	0.990909090909091	0.64078967552674	0.822001065880128
GO:0000217	DNA secondary structure binding	1/495	39/18639	0.0256410256410256	0.965501165501165	0.650348791198707	0.830387306613841
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	1/495	39/18639	0.0256410256410256	0.965501165501165	0.650348791198707	0.830387306613841
GO:0030165	PDZ domain binding	2/495	83/18639	0.0240963855421687	0.907338444687842	0.65105032920821	0.830387306613841
GO:0140104	molecular carrier activity	6/495	249/18639	0.0240963855421687	0.907338444687842	0.651738244633174	0.830387306613841
GO:0004527	exonuclease activity	2/495	84/18639	0.0238095238095238	0.896536796536797	0.65750324425604	0.833421947669355
GO:0004532	RNA exonuclease activity	1/495	40/18639	0.025	0.941363636363636	0.659654024981322	0.833421947669355
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	1/495	40/18639	0.025	0.941363636363636	0.659654024981322	0.833421947669355
GO:0050997	quaternary ammonium group binding	1/495	40/18639	0.025	0.941363636363636	0.659654024981322	0.833421947669355
GO:0071949	FAD binding	1/495	40/18639	0.025	0.941363636363636	0.659654024981322	0.833421947669355
GO:0001653	peptide receptor activity	3/495	128/18639	0.0234375	0.882528409090909	0.664686466497275	0.83837338236591
GO:0001530	lipopolysaccharide binding	1/495	41/18639	0.024390243902439	0.91840354767184	0.668712106471415	0.839233693621626
GO:0015175	neutral L-amino acid transmembrane transporter activity	1/495	41/18639	0.024390243902439	0.91840354767184	0.668712106471415	0.839233693621626
GO:0016877	ligase activity, forming carbon-sulfur bonds	1/495	41/18639	0.024390243902439	0.91840354767184	0.668712106471415	0.839233693621626
GO:0008307	structural constituent of muscle	1/495	42/18639	0.0238095238095238	0.896536796536797	0.677529587237984	0.846069285555891
GO:0016859	cis-trans isomerase activity	1/495	42/18639	0.0238095238095238	0.896536796536797	0.677529587237984	0.846069285555891
GO:0051879	Hsp90 protein binding	1/495	42/18639	0.0238095238095238	0.896536796536797	0.677529587237984	0.846069285555891
GO:0016651	oxidoreductase activity, acting on NAD(P)H	2/495	88/18639	0.0227272727272727	0.855785123966942	0.682362631681091	0.850693810688512
GO:0001223	transcription coactivator binding	1/495	44/18639	0.0227272727272727	0.855785123966942	0.694468090815381	0.862928172250795
GO:0043014	alpha-tubulin binding	1/495	44/18639	0.0227272727272727	0.855785123966942	0.694468090815381	0.862928172250795
GO:0072341	modified amino acid binding	2/495	91/18639	0.021978021978022	0.827572427572428	0.700024067277351	0.868398884118361
GO:0051539	4 iron, 4 sulfur cluster binding	1/495	45/18639	0.0222222222222222	0.836767676767677	0.702601368311826	0.87016254989935
GO:0016853	isomerase activity	4/495	180/18639	0.0222222222222222	0.836767676767677	0.707743975725485	0.875092304961068
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	1/495	46/18639	0.0217391304347826	0.818577075098814	0.710518563250282	0.87666015458064
GO:0051213	dioxygenase activity	2/495	93/18639	0.021505376344086	0.809775171065494	0.711340444155075	0.87666015458064
GO:0005504	fatty acid binding	1/495	47/18639	0.0212765957446809	0.801160541586074	0.718225405136535	0.880820407276565
GO:0099095	ligand-gated monoatomic anion channel activity	1/495	47/18639	0.0212765957446809	0.801160541586074	0.718225405136535	0.880820407276565
GO:0140359	ABC-type transporter activity	1/495	47/18639	0.0212765957446809	0.801160541586074	0.718225405136535	0.880820407276565
GO:0016879	ligase activity, forming carbon-nitrogen bonds	1/495	48/18639	0.0208333333333333	0.784469696969697	0.725727471856491	0.885693332751925
GO:0038187	pattern recognition receptor activity	1/495	48/18639	0.0208333333333333	0.784469696969697	0.725727471856491	0.885693332751925
GO:0140693	molecular condensate scaffold activity	1/495	48/18639	0.0208333333333333	0.784469696969697	0.725727471856491	0.885693332751925
GO:0005249	voltage-gated potassium channel activity	2/495	98/18639	0.0204081632653061	0.768460111317254	0.738073962445766	0.897699922268485
GO:0042626	ATPase-coupled transmembrane transporter activity	2/495	98/18639	0.0204081632653061	0.768460111317254	0.738073962445766	0.897699922268485
GO:0046943	carboxylic acid transmembrane transporter activity	4/495	188/18639	0.0212765957446809	0.801160541586074	0.739142034271528	0.897699922268485
GO:0005342	organic acid transmembrane transporter activity	4/495	189/18639	0.0211640211640212	0.796921596921597	0.742881604841883	0.900788805871075
GO:0015293	symporter activity	3/495	146/18639	0.0205479452054795	0.773723536737235	0.748435888586226	0.906064668979788
GO:0004864	protein phosphatase inhibitor activity	1/495	53/18639	0.0188679245283019	0.710463121783876	0.760351286361381	0.914607857236613
GO:0005246	calcium channel regulator activity	1/495	53/18639	0.0188679245283019	0.710463121783876	0.760351286361381	0.914607857236613
GO:0005544	calcium-dependent phospholipid binding	1/495	53/18639	0.0188679245283019	0.710463121783876	0.760351286361381	0.914607857236613
GO:0017046	peptide hormone binding	1/495	53/18639	0.0188679245283019	0.710463121783876	0.760351286361381	0.914607857236613
GO:0017069	snRNA binding	1/495	54/18639	0.0185185185185185	0.697306397306397	0.766733838457105	0.916429492632063
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	1/495	54/18639	0.0185185185185185	0.697306397306397	0.766733838457105	0.916429492632063
GO:0050661	NADP binding	1/495	54/18639	0.0185185185185185	0.697306397306397	0.766733838457105	0.916429492632063
GO:0051287	NAD binding	1/495	54/18639	0.0185185185185185	0.697306397306397	0.766733838457105	0.916429492632063
GO:0000149	SNARE binding	2/495	106/18639	0.0188679245283019	0.710463121783876	0.776443939581237	0.925098554596
GO:0004497	monooxygenase activity	2/495	106/18639	0.0188679245283019	0.710463121783876	0.776443939581237	0.925098554596
GO:0019212	phosphatase inhibitor activity	1/495	56/18639	0.0178571428571429	0.672402597402597	0.778994487479652	0.926671167570581
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	1/495	60/18639	0.0166666666666667	0.627575757575758	0.801619875586686	0.95092749175861
GO:0043022	ribosome binding	2/495	112/18639	0.0178571428571429	0.672402597402597	0.801910965825654	0.95092749175861
GO:0015631	tubulin binding	8/495	385/18639	0.0207792207792208	0.782432113341204	0.805781477670488	0.953845685235221
GO:0019905	syntaxin binding	1/495	61/18639	0.0163934426229508	0.617287630402385	0.806905314070167	0.953845685235221
GO:0015179	L-amino acid transmembrane transporter activity	1/495	62/18639	0.0161290322580645	0.60733137829912	0.812050209620564	0.958422896307656
GO:0101005	deubiquitinase activity	2/495	115/18639	0.0173913043478261	0.654861660079051	0.813654037759373	0.958812974073251
GO:0004674	protein serine/threonine kinase activity	9/495	433/18639	0.0207852193995381	0.782657988662607	0.816108365475167	0.960202498754377
GO:0009055	electron transfer activity	2/495	116/18639	0.0172413793103448	0.649216300940439	0.817428148109748	0.960254907217847
GO:0015399	primary active transmembrane transporter activity	3/495	166/18639	0.0180722891566265	0.680503833515882	0.820945859804749	0.962885097247626
GO:0022853	active monoatomic ion transmembrane transporter activity	2/495	118/18639	0.0169491525423729	0.638212634822804	0.824771820958761	0.965868088929933
GO:0019843	rRNA binding	1/495	65/18639	0.0153846153846154	0.579300699300699	0.826678444910897	0.966597622698611
GO:0004540	RNA nuclease activity	2/495	121/18639	0.0165289256198347	0.622389181066867	0.835290428397014	0.975153011756514
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	1/495	68/18639	0.0147058823529412	0.553743315508021	0.840170276959402	0.979331607663204
GO:0005267	potassium channel activity	2/495	124/18639	0.0161290322580645	0.60733137829912	0.845235692845333	0.982250637463302
GO:0008514	organic anion transmembrane transporter activity	5/495	269/18639	0.0185873605947955	0.699898614396756	0.845283417099894	0.982250637463302
GO:0140299	molecular sensor activity	1/495	71/18639	0.0140845070422535	0.530345710627401	0.852613823162615	0.987785668196126
GO:0043021	ribonucleoprotein complex binding	3/495	177/18639	0.0169491525423729	0.638212634822804	0.8526702315106	0.987785668196126
GO:0019783	ubiquitin-like protein peptidase activity	2/495	127/18639	0.015748031496063	0.592984967788117	0.854633053316727	0.988538693006906
GO:0031490	chromatin DNA binding	2/495	128/18639	0.015625	0.588352272727273	0.857648078504337	0.990350162722974
GO:0008017	microtubule binding	5/495	276/18639	0.0181159420289855	0.682147562582345	0.860476628012538	0.990350162722974
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	3/495	181/18639	0.0165745856353591	0.624108488196886	0.862930929624318	0.990350162722974
GO:0005085	guanyl-nucleotide exchange factor activity	4/495	230/18639	0.0173913043478261	0.654861660079051	0.863314306109246	0.990350162722974
GO:0016798	hydrolase activity, acting on glycosyl bonds	2/495	130/18639	0.0153846153846154	0.579300699300699	0.863507460746323	0.990350162722974
GO:0048029	monosaccharide binding	1/495	74/18639	0.0135135135135135	0.508845208845209	0.86409038102124	0.990350162722974
GO:0051536	iron-sulfur cluster binding	1/495	76/18639	0.0131578947368421	0.495454545454545	0.871241487120926	0.99400612849742
GO:0015078	proton transmembrane transporter activity	3/495	185/18639	0.0162162162162162	0.610614250614251	0.872559233161369	0.99400612849742
GO:0003724	RNA helicase activity	1/495	77/18639	0.012987012987013	0.489020070838253	0.874674954980385	0.99400612849742
GO:0051540	metal cluster binding	1/495	77/18639	0.012987012987013	0.489020070838253	0.874674954980385	0.99400612849742
GO:0015276	ligand-gated monoatomic ion channel activity	3/495	186/18639	0.0161290322580645	0.60733137829912	0.87487102394495	0.99400612849742
GO:0015297	antiporter activity	2/495	135/18639	0.0148148148148148	0.557845117845118	0.8772019714216	0.99400612849742
GO:0022834	ligand-gated channel activity	3/495	188/18639	0.0159574468085106	0.600870406189555	0.879383531413025	0.99400612849742
GO:0140597	protein carrier chaperone	3/495	188/18639	0.0159574468085106	0.600870406189555	0.879383531413025	0.99400612849742
GO:0008186	ATP-dependent activity, acting on RNA	1/495	79/18639	0.0126582278481013	0.476639815880322	0.881270187851605	0.99400612849742
GO:0015291	secondary active transmembrane transporter activity	5/495	287/18639	0.0174216027874564	0.656002534051314	0.881818782912324	0.99400612849742
GO:0140097	catalytic activity, acting on DNA	6/495	336/18639	0.0178571428571429	0.672402597402597	0.88507003328427	0.99400612849742
GO:0015101	organic cation transmembrane transporter activity	1/495	81/18639	0.0123456790123457	0.464870931537598	0.887519010678703	0.99400612849742
GO:0005254	chloride channel activity	1/495	83/18639	0.0120481927710843	0.453669222343921	0.893439583514949	0.99400612849742
GO:0022843	voltage-gated monoatomic cation channel activity	2/495	143/18639	0.013986013986014	0.526636999364272	0.896501888283949	0.99400612849742
GO:0035402	histone H3T11 kinase activity	4/495	247/18639	0.0161943319838057	0.60979020979021	0.896910177869868	0.99400612849742
GO:0015085	calcium ion transmembrane transporter activity	2/495	147/18639	0.0136054421768707	0.512306740878169	0.905057692529275	0.99400612849742
GO:0003727	single-stranded RNA binding	1/495	89/18639	0.0112359550561798	0.423084780388151	0.909399444970124	0.99400612849742
GO:0019842	vitamin binding	2/495	150/18639	0.0133333333333333	0.502060606060606	0.911036281006698	0.99400612849742
GO:0000510	H3-H4 histone complex chaperone activity	2/495	151/18639	0.0132450331125828	0.498735701384708	0.912949567822731	0.99400612849742
GO:0140584	chromatin extrusion motor activity	2/495	151/18639	0.0132450331125828	0.498735701384708	0.912949567822731	0.99400612849742
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	2/495	151/18639	0.0132450331125828	0.498735701384708	0.912949567822731	0.99400612849742
GO:0140849	ATP-dependent H2AZ histone chaperone activity	2/495	151/18639	0.0132450331125828	0.498735701384708	0.912949567822731	0.99400612849742
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	1/495	91/18639	0.010989010989011	0.413786213786214	0.914170343596971	0.99400612849742
GO:0015616	DNA translocase activity	2/495	152/18639	0.0131578947368421	0.495454545454545	0.914824250151603	0.99400612849742
GO:0140674	ATP-dependent histone chaperone activity	2/495	152/18639	0.0131578947368421	0.495454545454545	0.914824250151603	0.99400612849742
GO:0061775	cohesin loader activity	2/495	153/18639	0.0130718954248366	0.492216280451575	0.916661023635713	0.99400612849742
GO:0004518	nuclease activity	3/495	209/18639	0.0143540669856459	0.540495867768595	0.918696670898499	0.99400612849742
GO:0008094	ATP-dependent activity, acting on DNA	3/495	210/18639	0.0142857142857143	0.537922077922078	0.920239490885525	0.99400612849742
GO:0106310	protein serine kinase activity	6/495	361/18639	0.0166204986149584	0.625837320574163	0.920453393460107	0.99400612849742
GO:0022804	active transmembrane transporter activity	8/495	457/18639	0.0175054704595186	0.659160533121146	0.921687803978318	0.99400612849742
GO:0140658	ATP-dependent chromatin remodeler activity	2/495	158/18639	0.0126582278481013	0.476639815880322	0.925299933081642	0.99400612849742
GO:0030594	neurotransmitter receptor activity	1/495	97/18639	0.0103092783505155	0.388191190253046	0.927030476308569	0.99400612849742
GO:0022836	gated channel activity	5/495	318/18639	0.0157232704402516	0.592052601486564	0.927571981265468	0.99400612849742
GO:0003689	DNA clamp loader activity	2/495	160/18639	0.0125	0.470681818181818	0.928513408324281	0.99400612849742
GO:0015079	potassium ion transmembrane transporter activity	2/495	160/18639	0.0125	0.470681818181818	0.928513408324281	0.99400612849742
GO:0008170	N-methyltransferase activity	1/495	98/18639	0.0102040816326531	0.384230055658627	0.928978481606123	0.99400612849742
GO:0030527	structural constituent of chromatin	1/495	98/18639	0.0102040816326531	0.384230055658627	0.928978481606123	0.99400612849742
GO:0016887	ATP hydrolysis activity	7/495	417/18639	0.0167865707434053	0.632090691083497	0.92929613473557	0.99400612849742
GO:0015081	sodium ion transmembrane transporter activity	2/495	164/18639	0.0121951219512195	0.45920177383592	0.934552918728435	0.99400612849742
GO:0140713	histone chaperone activity	2/495	164/18639	0.0121951219512195	0.45920177383592	0.934552918728435	0.99400612849742
GO:0015171	amino acid transmembrane transporter activity	1/495	102/18639	0.00980392156862745	0.369162210338681	0.936265102164565	0.99400612849742
GO:0005253	monoatomic anion channel activity	1/495	103/18639	0.00970873786407767	0.365578111209179	0.937967037452289	0.99400612849742
GO:0016874	ligase activity	2/495	167/18639	0.0119760479041916	0.450952640174197	0.938762253091579	0.99400612849742
GO:0004843	cysteine-type deubiquitinase activity	1/495	108/18639	0.00925925925925926	0.348653198653199	0.945819997393889	0.99400612849742
GO:0005244	voltage-gated monoatomic ion channel activity	2/495	173/18639	0.0115606936416185	0.435312664214398	0.946422829643069	0.99400612849742
GO:0140030	modification-dependent protein binding	2/495	173/18639	0.0115606936416185	0.435312664214398	0.946422829643069	0.99400612849742
GO:0022832	voltage-gated channel activity	2/495	175/18639	0.0114285714285714	0.430337662337662	0.948767197921564	0.99400612849742
GO:0005200	structural constituent of cytoskeleton	1/495	112/18639	0.00892857142857143	0.336201298701299	0.951381602040668	0.99400612849742
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	3/495	243/18639	0.0123456790123457	0.464870931537598	0.958322505714239	0.99400612849742
GO:0004676	3-phosphoinositide-dependent protein kinase activity	3/495	245/18639	0.0122448979591837	0.461076066790353	0.959968950166563	0.99400612849742
GO:0004711	ribosomal protein S6 kinase activity	3/495	245/18639	0.0122448979591837	0.461076066790353	0.959968950166563	0.99400612849742
GO:0035175	histone H3S10 kinase activity	3/495	245/18639	0.0122448979591837	0.461076066790353	0.959968950166563	0.99400612849742
GO:0035979	histone H2AXS139 kinase activity	3/495	245/18639	0.0122448979591837	0.461076066790353	0.959968950166563	0.99400612849742
GO:0044022	histone H3S28 kinase activity	3/495	245/18639	0.0122448979591837	0.461076066790353	0.959968950166563	0.99400612849742
GO:0044023	histone H4S1 kinase activity	3/495	245/18639	0.0122448979591837	0.461076066790353	0.959968950166563	0.99400612849742
GO:0044024	histone H2AS1 kinase activity	3/495	245/18639	0.0122448979591837	0.461076066790353	0.959968950166563	0.99400612849742
GO:0044025	histone H2BS14 kinase activity	3/495	245/18639	0.0122448979591837	0.461076066790353	0.959968950166563	0.99400612849742
GO:0072354	histone H3T3 kinase activity	3/495	245/18639	0.0122448979591837	0.461076066790353	0.959968950166563	0.99400612849742
GO:0072371	histone H2AS121 kinase activity	3/495	245/18639	0.0122448979591837	0.461076066790353	0.959968950166563	0.99400612849742
GO:0072518	Rho-dependent protein serine/threonine kinase activity	3/495	245/18639	0.0122448979591837	0.461076066790353	0.959968950166563	0.99400612849742
GO:0140823	histone H2BS36 kinase activity	3/495	245/18639	0.0122448979591837	0.461076066790353	0.959968950166563	0.99400612849742
GO:0140855	histone H3S57 kinase activity	3/495	245/18639	0.0122448979591837	0.461076066790353	0.959968950166563	0.99400612849742
GO:0140995	histone H2A kinase activity	3/495	245/18639	0.0122448979591837	0.461076066790353	0.959968950166563	0.99400612849742
GO:0140997	histone H4 kinase activity	3/495	245/18639	0.0122448979591837	0.461076066790353	0.959968950166563	0.99400612849742
GO:0140998	histone H2B kinase activity	3/495	245/18639	0.0122448979591837	0.461076066790353	0.959968950166563	0.99400612849742
GO:1990244	histone H2AT120 kinase activity	3/495	245/18639	0.0122448979591837	0.461076066790353	0.959968950166563	0.99400612849742
GO:0004677	DNA-dependent protein kinase activity	3/495	246/18639	0.0121951219512195	0.45920177383592	0.960769121812469	0.99400612849742
GO:0140857	histone H3T45 kinase activity	3/495	246/18639	0.0121951219512195	0.45920177383592	0.960769121812469	0.99400612849742
GO:0035403	histone H3T6 kinase activity	3/495	247/18639	0.0121457489878543	0.457342657342657	0.961554272762583	0.99400612849742
GO:0042393	histone binding	3/495	247/18639	0.0121457489878543	0.457342657342657	0.961554272762583	0.99400612849742
GO:0015108	chloride transmembrane transporter activity	1/495	121/18639	0.00826446280991736	0.311194590533434	0.961899853455868	0.99400612849742
GO:0004679	AMP-activated protein kinase activity	3/495	248/18639	0.0120967741935484	0.45549853372434	0.962324658266427	0.99400612849742
GO:0005262	calcium channel activity	1/495	131/18639	0.00763358778625954	0.287439278278973	0.970944545052957	0.999315317078002
GO:0099094	ligand-gated monoatomic cation channel activity	1/495	136/18639	0.00735294117647059	0.276871657754011	0.974628039793608	0.999315317078002
GO:0140101	catalytic activity, acting on a tRNA	1/495	139/18639	0.00719424460431655	0.270896010464356	0.976610438204743	0.999315317078002
GO:0005216	monoatomic ion channel activity	6/495	448/18639	0.0133928571428571	0.504301948051948	0.980615016227302	0.999315317078002
GO:0046873	metal ion transmembrane transporter activity	6/495	450/18639	0.0133333333333333	0.502060606060606	0.9812730277	0.999315317078002
GO:0005261	monoatomic cation channel activity	4/495	341/18639	0.0117302052785924	0.441695547853906	0.981515392751426	0.999315317078002
GO:0008509	monoatomic anion transmembrane transporter activity	1/495	149/18639	0.00671140939597315	0.252715070164735	0.982167714627501	0.999315317078002
GO:0004386	helicase activity	1/495	155/18639	0.00645161290322581	0.242932551319648	0.98484740724741	0.999315317078002
GO:0015103	inorganic anion transmembrane transporter activity	1/495	165/18639	0.00606060606060606	0.228209366391185	0.988450359489964	0.999315317078002
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	1/495	167/18639	0.00598802395209581	0.225476320087099	0.98906101553094	0.999315317078002
GO:0016755	aminoacyltransferase activity	6/495	496/18639	0.0120967741935484	0.45549853372434	0.991721136912948	0.999315317078002
GO:0140098	catalytic activity, acting on RNA	4/495	387/18639	0.0103359173126615	0.389194268264036	0.992605355430187	0.999315317078002
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	2/495	268/18639	0.00746268656716418	0.281004070556309	0.994117290006322	0.999315317078002
GO:0001217	DNA-binding transcription repressor activity	2/495	278/18639	0.00719424460431655	0.270896010464356	0.995374173313965	0.999315317078002
GO:0061630	ubiquitin protein ligase activity	3/495	353/18639	0.0084985835694051	0.320010301313418	0.995991051787218	0.999315317078002
GO:0008168	methyltransferase activity	1/495	204/18639	0.00490196078431373	0.18458110516934	0.99599993250057	0.999315317078002
GO:0019787	ubiquitin-like protein transferase activity	5/495	479/18639	0.0104384133611691	0.393053710381477	0.99613748771658	0.999315317078002
GO:0016741	transferase activity, transferring one-carbon groups	1/495	215/18639	0.00465116279069767	0.175137420718816	0.997035142534052	0.999315317078002
GO:0061659	ubiquitin-like protein ligase activity	3/495	372/18639	0.00806451612903226	0.30366568914956	0.997379197243313	0.999315317078002
GO:0004842	ubiquitin-protein transferase activity	4/495	449/18639	0.0089086859688196	0.335452520753189	0.99796942888038	0.999315317078002
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	1/495	229/18639	0.00436681222707424	0.164430329495832	0.997975328549552	0.999315317078002
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	4/495	484/18639	0.00826446280991736	0.311194590533434	0.999044572267095	0.999315317078002
GO:0001216	DNA-binding transcription activator activity	4/495	491/18639	0.00814663951120163	0.306758007776338	0.999179827418287	0.999315317078002
GO:0045182	translation regulator activity	2/495	356/18639	0.00561797752808989	0.211542390194076	0.999315317078002	0.999315317078002