category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Metabolism	Energy metabolism	hsa00190	Oxidative phosphorylation	8/29	138/9376	18.7426286856572	MT-CO2/MT-CO1/MT-ND4/MT-ATP6/MT-CO3/MT-ND2/MT-ND5/MT-ND1	11.6954528885211
Human Diseases	Cardiovascular disease	hsa05415	Diabetic cardiomyopathy	9/29	205/9376	14.1941126997477	MT-CO2/MT-CO1/MT-ND4/MT-ATP6/MT-CO3/MT-ND2/MT-ND5/MT-ND1/CTSD	10.63891377214
Human Diseases	Neurodegenerative disease	hsa05012	Parkinson disease	9/29	268/9376	10.8574369531652	MT-CO2/MT-CO1/MT-ND4/MT-ATP6/MT-CO3/MT-ND2/MT-ND5/MT-ND1/GNAI2	9.11944503135958
Human Diseases	Cancer: overview	hsa05208	Chemical carcinogenesis - reactive oxygen species	8/29	227/9376	11.3941971745405	MT-CO2/MT-CO1/MT-ND4/MT-ATP6/MT-CO3/MT-ND2/MT-ND5/MT-ND1	8.83009917953482
Organismal Systems	Environmental adaptation	hsa04714	Thermogenesis	8/29	235/9376	11.0063096111519	MT-CO2/MT-CO1/MT-ND4/MT-ATP6/MT-CO3/MT-ND2/MT-ND5/MT-ND1	8.65285704997598
Human Diseases	Neurodegenerative disease	hsa05020	Prion disease	8/29	275/9376	9.40539184952978	MT-CO2/MT-CO1/MT-ND4/MT-ATP6/MT-CO3/MT-ND2/MT-ND5/MT-ND1	7.88003724311825
Human Diseases	Neurodegenerative disease	hsa05016	Huntington disease	8/29	308/9376	8.39767129422302	MT-CO2/MT-CO1/MT-ND4/MT-ATP6/MT-CO3/MT-ND2/MT-ND5/MT-ND1	7.35297599981207
Organismal Systems	Nervous system	hsa04723	Retrograde endocannabinoid signaling	6/29	149/9376	13.0192085165471	MT-ND4/GNG11/MT-ND2/MT-ND5/MT-ND1/GNAI2	8.23734506978311
Human Diseases	Neurodegenerative disease	hsa05014	Amyotrophic lateral sclerosis	8/29	368/9376	7.02848575712144	MT-CO2/MT-CO1/MT-ND4/MT-ATP6/MT-CO3/MT-ND2/MT-ND5/MT-ND1	6.57152970822641
Human Diseases	Neurodegenerative disease	hsa05010	Alzheimer disease	8/29	388/9376	6.66619267685745	MT-CO2/MT-CO1/MT-ND4/MT-ATP6/MT-CO3/MT-ND2/MT-ND5/MT-ND1	6.34927569493758
Human Diseases	Neurodegenerative disease	hsa05022	Pathways of neurodegeneration - multiple diseases	8/29	480/9376	5.38850574712644	MT-CO2/MT-CO1/MT-ND4/MT-ATP6/MT-CO3/MT-ND2/MT-ND5/MT-ND1	5.49779344083722
Human Diseases	Infectious disease: parasitic	hsa05143	African trypanosomiasis	3/29	37/9376	26.2143522833178	HBB/HBA2/HBA1	8.55947260794858
Human Diseases	Infectious disease: parasitic	hsa05144	Malaria	3/29	50/9376	19.3986206896552	HBB/HBA2/HBA1	7.26559320503976
Organismal Systems	Circulatory system	hsa04260	Cardiac muscle contraction	3/29	87/9376	11.1486325802616	MT-CO2/MT-CO1/MT-CO3	5.29701484829569
Environmental Information Processing	Signal transduction	hsa04371	Apelin signaling pathway	3/29	140/9376	6.92807881773399	GNG11/CCND1/GNAI2	3.93626692276268
NA	NA	hsa03272	Virion - Hepatitis viruses	2/29	48/9376	13.4712643678161	CLDN5/CD9	4.82486705623788
Human Diseases	Endocrine and metabolic disease	hsa04932	Non-alcoholic fatty liver disease	3/29	157/9376	6.17790467823413	MT-CO2/MT-CO1/MT-CO3	3.64426949420586
Human Diseases	Cardiovascular disease	hsa05416	Viral myocarditis	2/29	70/9376	9.23743842364532	HLA-DRB5/CCND1	3.85308147899559
Organismal Systems	Immune system	hsa04062	Chemokine signaling pathway	3/29	193/9376	5.02554940146507	CCL21/GNG11/GNAI2	3.1474586904182
Human Diseases	Infectious disease: viral	hsa05169	Epstein-Barr virus infection	3/29	205/9376	4.7313708999159	HLA-DRB5/CCND1/ISG15	3.00874595809969
Organismal Systems	Nervous system	hsa04727	GABAergic synapse	2/29	89/9376	7.26540100736149	GNG11/GNAI2	3.30791749453765
Human Diseases	Substance dependence	hsa05032	Morphine addiction	2/29	91/9376	7.10572186434255	GNG11/GNAI2	3.25998254560869
Human Diseases	Infectious disease: viral	hsa05163	Human cytomegalovirus infection	3/29	227/9376	4.27282394045268	GNG11/CCND1/GNAI2	2.7803359418791
Organismal Systems	Environmental adaptation	hsa04713	Circadian entrainment	2/29	97/9376	6.66619267685745	GNG11/GNAI2	3.12446118657273
Human Diseases	Infectious disease: bacterial	hsa05150	Staphylococcus aureus infection	2/29	99/9376	6.53152211772901	HLA-DRB5/DEFB1	3.08181800450103
Organismal Systems	Immune system	hsa04640	Hematopoietic cell lineage	2/29	100/9376	6.46620689655172	HLA-DRB5/CD9	3.06093573497984
Human Diseases	Infectious disease: parasitic	hsa05145	Toxoplasmosis	2/29	112/9376	5.77339901477832	HLA-DRB5/GNAI2	2.83064882287532
Organismal Systems	Nervous system	hsa04725	Cholinergic synapse	2/29	115/9376	5.62278860569715	GNG11/GNAI2	2.77825770866744
Organismal Systems	Nervous system	hsa04726	Serotonergic synapse	2/29	115/9376	5.62278860569715	GNG11/GNAI2	2.77825770866744
Organismal Systems	Immune system	hsa04670	Leukocyte transendothelial migration	2/29	116/9376	5.5743162901308	CLDN5/GNAI2	2.76120217993094
Organismal Systems	Nervous system	hsa04724	Glutamatergic synapse	2/29	116/9376	5.5743162901308	GNG11/GNAI2	2.76120217993094
Environmental Information Processing	Signal transduction	hsa04071	Sphingolipid signaling pathway	2/29	125/9376	5.17296551724138	GNAI2/CTSD	2.6160978134544
Organismal Systems	Endocrine system	hsa04926	Relaxin signaling pathway	2/29	130/9376	4.97400530503979	GNG11/GNAI2	2.54139218406957
Organismal Systems	Nervous system	hsa04728	Dopaminergic synapse	2/29	133/9376	4.86180969665543	GNG11/GNAI2	2.49838134514685
Organismal Systems	Endocrine system	hsa04915	Estrogen signaling pathway	2/29	139/9376	4.65194740759117	GNAI2/CTSD	2.41610029666488
NA	NA	hsa04518	Integrin signaling	2/29	154/9376	4.19883564711151	CCND1/TNXB	2.22940127072753
Organismal Systems	Endocrine system	hsa04921	Oxytocin signaling pathway	2/29	154/9376	4.19883564711151	CCND1/GNAI2	2.22940127072753
Human Diseases	Infectious disease: viral	hsa05165	Human papillomavirus infection	3/29	333/9376	2.91270580925753	CCND1/ISG15/TNXB	1.97953207902656
Human Diseases	Endocrine and metabolic disease	hsa04934	Cushing syndrome	2/29	155/9376	4.17174638487208	CCND1/GNAI2	2.2178072937409
Human Diseases	Infectious disease: viral	hsa05160	Hepatitis C	2/29	156/9376	4.14500442086649	CCND1/CLDN5	2.20631041303436
Environmental Information Processing	Signaling molecules and interaction	hsa04514	Cell adhesion molecule (CAM) interaction	2/29	160/9376	4.04137931034483	HLA-DRB5/CLDN5	2.16126420806365
Human Diseases	Immune disease	hsa05310	Asthma	1/29	32/9376	10.1034482758621	HLA-DRB5	2.87318121975862
Cellular Processes	Cellular community - eukaryotes	hsa04530	Tight junction	2/29	170/9376	3.80365111561866	CCND1/CLDN5	2.05476169305236
Environmental Information Processing	Signal transduction	hsa04151	PI3K-Akt signaling pathway	3/29	362/9376	2.67936749857116	GNG11/CCND1/TNXB	1.81505490997422
Human Diseases	Infectious disease: bacterial	hsa05152	Tuberculosis	2/29	181/9376	3.57248999809488	HLA-DRB5/CTSD	1.94655030322285
Human Diseases	Cancer: specific types	hsa05216	Thyroid cancer	1/29	37/9376	8.7381174277726	CCND1	2.62684535441867
Human Diseases	Immune disease	hsa05330	Allograft rejection	1/29	39/9376	8.29000884173298	HLA-DRB5	2.54100310048858
Human Diseases	Substance dependence	hsa05034	Alcoholism	2/29	191/9376	3.38544863693808	GNG11/GNAI2	1.85522115949644
Human Diseases	Cancer: specific types	hsa05219	Bladder cancer	1/29	41/9376	7.88561816652649	CCND1	2.46108276349821
Cellular Processes	Cell growth and death	hsa04216	Ferroptosis	1/29	42/9376	7.69786535303777	CP	2.42312420248344
Human Diseases	Infectious disease: viral	hsa05167	Kaposi sarcoma-associated herpesvirus infection	2/29	196/9376	3.2990851513019	GNG11/CCND1	1.81180005051328
NA	NA	hsa04082	Neuroactive ligand signaling	2/29	199/9376	3.24935019927222	GNG11/GNAI2	1.78641256095893
Human Diseases	Endocrine and metabolic disease	hsa04940	Type I diabetes mellitus	1/29	44/9376	7.34796238244514	HLA-DRB5	2.3508332974587
Cellular Processes	Cellular community - eukaryotes	hsa04510	Focal adhesion	2/29	203/9376	3.18532359436046	CCND1/TNXB	1.75330145310225
Environmental Information Processing	Membrane transport	hsa02010	ABC transporters	1/29	45/9376	7.18467432950192	DEFB1	2.31636777050054
Human Diseases	Immune disease	hsa05332	Graft-versus-host disease	1/29	45/9376	7.18467432950192	HLA-DRB5	2.31636777050054
Metabolism	Metabolism of cofactors and vitamins	hsa00860	Porphyrin metabolism	1/29	46/9376	7.02848575712144	CP	2.28294184720373
Human Diseases	Infectious disease: viral	hsa05170	Human immunodeficiency virus 1 infection	2/29	214/9376	3.02159200773445	GNG11/GNAI2	1.66630221150609
Human Diseases	Substance dependence	hsa05030	Cocaine addiction	1/29	49/9376	6.5981703026038	GNAI2	2.18837464092481
Organismal Systems	Immune system	hsa04672	Intestinal immune network for IgA production	1/29	50/9376	6.46620689655172	HLA-DRB5	2.15859853599015
Human Diseases	Cancer: overview	hsa05207	Chemical carcinogenesis - receptor activation	2/29	217/9376	2.9798188463372	CCND1/GNAI2	1.64353821763697
NA	NA	hsa04081	Hormone signaling	2/29	219/9376	2.9526058888364	GNG11/GNAI2	1.62857798933398
Genetic Information Processing	Translation	hsa03010	Ribosome	2/29	222/9376	2.91270580925753	MT-RNR2/MT-RNR1	1.60645189759465
Human Diseases	Infectious disease: viral	hsa05166	Human T-cell leukemia virus 1 infection	2/29	224/9376	2.88669950738916	HLA-DRB5/CCND1	1.59190539766271
Human Diseases	Immune disease	hsa05320	Autoimmune thyroid disease	1/29	54/9376	5.98722860791826	HLA-DRB5	2.04715215351658
Environmental Information Processing	Signal transduction	hsa04340	Hedgehog signaling pathway	1/29	56/9376	5.77339901477832	CCND1	1.99554861434722
Cellular Processes	Cell motility	hsa04820	Cytoskeleton in muscle cells	2/29	233/9376	2.77519609294065	SYNE2/SYNE1	1.52836980775411
Organismal Systems	Endocrine system	hsa04923	Regulation of lipolysis in adipocytes	1/29	59/9376	5.47983635300994	GNAI2	1.92264287794388
Human Diseases	Cancer: specific types	hsa05213	Endometrial cancer	1/29	59/9376	5.47983635300994	CCND1	1.92264287794388
Organismal Systems	Nervous system	hsa04730	Long-term depression	1/29	60/9376	5.38850574712644	GNAI2	1.89944215620828
Organismal Systems	Digestive system	hsa04978	Mineral absorption	1/29	61/9376	5.30016958733748	MT2A	1.87675502360968
Human Diseases	Immune disease	hsa05321	Inflammatory bowel disease	1/29	66/9376	4.89864158829676	HLA-DRB5	1.7703492623243
Human Diseases	Cancer: specific types	hsa05221	Acute myeloid leukemia	1/29	68/9376	4.75456389452333	CCND1	1.73074977699811
Organismal Systems	Endocrine system	hsa04924	Renin secretion	1/29	69/9376	4.68565717141429	GNAI2	1.71152457845156
Organismal Systems	Endocrine system	hsa04917	Prolactin signaling pathway	1/29	71/9376	4.55366682855755	CCND1	1.67415710321969
Organismal Systems	Immune system	hsa04622	RIG-I-like receptor signaling pathway	1/29	72/9376	4.4904214559387	ISG15	1.65599027799074
Human Diseases	Cancer: specific types	hsa05218	Melanoma	1/29	73/9376	4.4289088332546	CCND1	1.63815266909146
Human Diseases	Cancer: specific types	hsa05223	Non-small cell lung cancer	1/29	73/9376	4.4289088332546	CCND1	1.63815266909146
Cellular Processes	Cell growth and death	hsa04115	p53 signaling pathway	1/29	75/9376	4.31080459770115	CCND1	1.60342213599979
Organismal Systems	Digestive system	hsa04971	Gastric acid secretion	1/29	76/9376	4.2540834845735	GNAI2	1.58650895709468
Human Diseases	Cancer: specific types	hsa05214	Glioma	1/29	76/9376	4.2540834845735	CCND1	1.58650895709468
Human Diseases	Cancer: specific types	hsa05212	Pancreatic cancer	1/29	77/9376	4.19883564711151	CCND1	1.56988442786184
Human Diseases	Cancer: specific types	hsa05220	Chronic myeloid leukemia	1/29	77/9376	4.19883564711151	CCND1	1.56988442786184
Human Diseases	Infectious disease: bacterial	hsa05133	Pertussis	1/29	78/9376	4.14500442086649	GNAI2	1.55353952313067
Human Diseases	Infectious disease: parasitic	hsa05140	Leishmaniasis	1/29	78/9376	4.14500442086649	HLA-DRB5	1.55353952313067
Organismal Systems	Immune system	hsa04612	Antigen processing and presentation	1/29	82/9376	3.94280908326325	HLA-DRB5	1.49078905560756
Human Diseases	Cancer: specific types	hsa05210	Colorectal cancer	1/29	87/9376	3.7162108600872	CCND1	1.41770914881353
Environmental Information Processing	Signaling molecules and interaction	hsa04512	ECM-receptor interaction	1/29	89/9376	3.63270050368074	TNXB	1.38997584412735
Cellular Processes	Cellular community - eukaryotes	hsa04540	Gap junction	1/29	89/9376	3.63270050368074	GNAI2	1.38997584412735
Organismal Systems	Immune system	hsa04658	Th1 and Th2 cell differentiation	1/29	93/9376	3.47645532072673	HLA-DRB5	1.33683039648362
Human Diseases	Cancer: specific types	hsa05222	Small cell lung cancer	1/29	93/9376	3.47645532072673	CCND1	1.33683039648362
Human Diseases	Immune disease	hsa05323	Rheumatoid arthritis	1/29	95/9376	3.4032667876588	HLA-DRB5	1.31133881650534
Human Diseases	Cancer: overview	hsa05206	MicroRNAs in cancer	2/29	323/9376	2.0019216397993	CCND1/TNXB	1.02067452066458
Human Diseases	Drug resistance: antineoplastic	hsa01522	Endocrine resistance	1/29	99/9376	3.26576105886451	CCND1	1.26234028834955
Environmental Information Processing	Signaling molecules and interaction	hsa04061	Viral protein interaction with cytokine and cytokine receptor	1/29	100/9376	3.23310344827586	CCL21	1.25048068506999
Organismal Systems	Endocrine system	hsa04916	Melanogenesis	1/29	101/9376	3.20109252304541	GNAI2	1.2387696087314
Human Diseases	Endocrine and metabolic disease	hsa04933	AGE-RAGE signaling pathway in diabetic complications	1/29	101/9376	3.20109252304541	CCND1	1.2387696087314
Organismal Systems	Digestive system	hsa04974	Protein digestion and absorption	1/29	103/9376	3.13893538667559	COL18A1	1.21577907333166
Human Diseases	Infectious disease: parasitic	hsa05142	Chagas disease	1/29	103/9376	3.13893538667559	GNAI2	1.21577907333166
Environmental Information Processing	Signal transduction	hsa04064	NF-kappa B signaling pathway	1/29	105/9376	3.07914614121511	CCL21	1.19334190478168
Human Diseases	Cancer: specific types	hsa05215	Prostate cancer	1/29	106/9376	3.05009759271308	CCND1	1.18232294267025
Organismal Systems	Immune system	hsa04659	Th17 cell differentiation	1/29	109/9376	2.96614995254666	HLA-DRB5	1.15002907523853
Organismal Systems	Endocrine system	hsa04914	Progesterone-mediated oocyte maturation	1/29	110/9376	2.93918495297806	GNAI2	1.13950948123972
Organismal Systems	Endocrine system	hsa04928	Parathyroid hormone synthesis, secretion and action	1/29	115/9376	2.81139430284858	GNAI2	1.08863299072842
Environmental Information Processing	Signal transduction	hsa04152	AMPK signaling pathway	1/29	122/9376	2.65008479366874	CCND1	1.02180952243785
Organismal Systems	Endocrine system	hsa04919	Thyroid hormone signaling pathway	1/29	122/9376	2.65008479366874	CCND1	1.02180952243785
Organismal Systems	Endocrine system	hsa04935	Growth hormone synthesis, secretion and action	1/29	122/9376	2.65008479366874	GNAI2	1.02180952243785
Organismal Systems	Immune system	hsa04611	Platelet activation	1/29	126/9376	2.56595511767926	GNAI2	0.98569427115447
Environmental Information Processing	Signal transduction	hsa04068	FoxO signaling pathway	1/29	133/9376	2.43090484832772	CCND1	0.925717800863743
Human Diseases	Infectious disease: viral	hsa05162	Measles	1/29	136/9376	2.37728194726166	CCND1	0.901166086059234
Cellular Processes	Cell growth and death	hsa04210	Apoptosis	1/29	137/9376	2.35992952428895	CTSD	0.893125971030511
Human Diseases	Immune disease	hsa05322	Systemic lupus erythematosus	1/29	143/9376	2.26091150229081	HLA-DRB5	0.846310488525546
Human Diseases	Endocrine and metabolic disease	hsa04936	Alcoholic liver disease	1/29	144/9376	2.24521072796935	CCND1	0.838734905939318
Human Diseases	Cancer: specific types	hsa05224	Breast cancer	1/29	148/9376	2.18452935694315	CCND1	0.809042635859416
Human Diseases	Cancer: specific types	hsa05226	Gastric cancer	1/29	150/9376	2.15540229885057	CCND1	0.794548930659412
Organismal Systems	Circulatory system	hsa04261	Adrenergic signaling in cardiomyocytes	1/29	154/9376	2.09941782355575	GNAI2	0.766229892151208
Cellular Processes	Transport and catabolism	hsa04145	Phagosome	1/29	155/9376	2.08587319243604	HLA-DRB5	0.759284379655561
Cellular Processes	Cell growth and death	hsa04218	Cellular senescence	1/29	157/9376	2.05930155941138	CCND1	0.745548749546336
Environmental Information Processing	Signal transduction	hsa04390	Hippo signaling pathway	1/29	157/9376	2.05930155941138	CCND1	0.745548749546336
Cellular Processes	Cell growth and death	hsa04110	Cell cycle	1/29	158/9376	2.04626800523789	CCND1	0.73875707351874
Environmental Information Processing	Signal transduction	hsa04022	cGMP-PKG signaling pathway	1/29	166/9376	1.94765267968425	GNAI2	0.686154537622838
Environmental Information Processing	Signal transduction	hsa04630	JAK-STAT signaling pathway	1/29	168/9376	1.92446633825944	CCND1	0.673459686091649
Cellular Processes	Transport and catabolism	hsa04140	Autophagy - animal	1/29	169/9376	1.91307896347684	CTSD	0.667177103674059
Human Diseases	Cancer: specific types	hsa05225	Hepatocellular carcinoma	1/29	170/9376	1.90182555780933	CCND1	0.660936947425175
Human Diseases	Infectious disease: viral	hsa05164	Influenza A	1/29	173/9376	1.86884592385888	HLA-DRB5	0.642465223455525
Environmental Information Processing	Signal transduction	hsa04310	Wnt signaling pathway	1/29	178/9376	1.81635025184037	CCND1	0.612474970433216
Human Diseases	Infectious disease: viral	hsa05168	Herpes simplex virus 1 infection	1/29	180/9376	1.79616858237548	HLA-DRB5	0.600745218669489
Organismal Systems	Development and regeneration	hsa04360	Axon guidance	1/29	184/9376	1.75712143928036	GNAI2	0.577720746397596
Human Diseases	Infectious disease: bacterial	hsa05130	Pathogenic Escherichia coli infection	1/29	200/9376	1.61655172413793	CLDN5	0.490915028823147
Human Diseases	Cancer: overview	hsa05205	Proteoglycans in cancer	1/29	204/9376	1.58485463150778	CCND1	0.470413211074693
Human Diseases	Cancer: overview	hsa05203	Viral carcinogenesis	1/29	205/9376	1.5771236333053	CCND1	0.46535668675292
Environmental Information Processing	Signal transduction	hsa04015	Rap1 signaling pathway	1/29	212/9376	1.52504879635654	GNAI2	0.430698712219257
NA	NA	hsa04382	Cornified envelope formation	1/29	217/9376	1.4899094231686	CLDN5	0.406696229631174
Environmental Information Processing	Signal transduction	hsa04024	cAMP signaling pathway	1/29	226/9376	1.43057674702472	GNAI2	0.364957893063779
Environmental Information Processing	Signal transduction	hsa04014	Ras signaling pathway	1/29	238/9376	1.35844682700666	GNG11	0.311986755588627
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	1/29	238/9376	1.35844682700666	ISG15	0.311986755588627
Cellular Processes	Transport and catabolism	hsa04142	Lysosome biogenesis	1/29	250/9376	1.29324137931034	CTSD	0.261760156435578
Environmental Information Processing	Signaling molecules and interaction	hsa04060	Cytokine-cytokine receptor interaction	1/29	298/9376	1.08493404304559	CCL21	0.08299336174901