ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0003823 antigen binding 14/82 174/18639 0.0804597701149425 18.2888982338099 2.85078295820546e-14 7.72562181673681e-12 GO:0034987 immunoglobulin receptor binding 5/82 19/18639 0.263157894736842 59.8170731707317 1.61350239605138e-08 2.18629574664962e-06 GO:0042605 peptide antigen binding 5/82 45/18639 0.111111111111111 25.2560975609756 1.55008578500473e-06 0.000140024415912094 GO:0031720 haptoglobin binding 3/82 10/18639 0.3 68.1914634146341 9.63155421826536e-06 0.000652537798287478 GO:0042608 T cell receptor binding 3/82 11/18639 0.272727272727273 61.9922394678492 1.32013321486741e-05 0.000715512202458138 GO:0005344 oxygen carrier activity 3/82 14/18639 0.214285714285714 48.7081881533101 2.88464702739088e-05 0.00130289890737155 GO:0001664 G protein-coupled receptor binding 8/82 297/18639 0.0269360269360269 6.12269031781227 4.85323798244261e-05 0.00187889641891707 GO:0004601 peroxidase activity 4/82 57/18639 0.0701754385964912 15.9512195121951 0.0001150972193071 0.00389891830402801 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 4/82 59/18639 0.0677966101694915 15.410500206697 0.000131731736935072 0.00396658896771161 GO:0023026 MHC class II protein complex binding 3/82 27/18639 0.111111111111111 25.2560975609756 0.000222428829995946 0.00602782129289013 GO:0019825 oxygen binding 3/82 34/18639 0.0882352941176471 20.05631276901 0.000445062634507596 0.0109647249046871 GO:0016209 antioxidant activity 4/82 86/18639 0.0465116279069767 10.5723199092456 0.000561770373836157 0.0119330258486978 GO:0023023 MHC protein complex binding 3/82 37/18639 0.0810810810810811 18.4301252471984 0.000572432974291774 0.0119330258486978 GO:0042277 peptide binding 6/82 249/18639 0.0240963855421687 5.47722597707905 0.000803015475497403 0.0155440852756997 GO:0008009 chemokine activity 3/82 45/18639 0.0666666666666667 15.1536585365854 0.00101928188449535 0.0184150260465493 GO:0048020 CCR chemokine receptor binding 3/82 50/18639 0.06 13.6382926829268 0.00138581784886568 0.0230368576995963 GO:0031994 insulin-like growth factor I binding 2/82 13/18639 0.153846153846154 34.9699812382739 0.00144511653466102 0.0230368576995963 GO:0005520 insulin-like growth factor binding 2/82 19/18639 0.105263157894737 23.9268292682927 0.00311436221554905 0.0468884533563219 GO:0020037 heme binding 4/82 142/18639 0.028169014084507 6.40295431123325 0.00356679317249456 0.0504273315876918 GO:0005125 cytokine activity 5/82 234/18639 0.0213675213675214 4.85694183864916 0.00372157428691453 0.0504273315876918 GO:0042379 chemokine receptor binding 3/82 72/18639 0.0416666666666667 9.47103658536585 0.00393431938623188 0.0507714549366114 GO:0019209 kinase activator activity 4/82 148/18639 0.027027027027027 6.14337508239947 0.00413348176802412 0.0509169799606608 GO:0046906 tetrapyrrole binding 4/82 152/18639 0.0263157894736842 5.98170731707317 0.0045433533302485 0.0512201949962562 GO:0005506 iron ion binding 4/82 154/18639 0.025974025974026 5.90402280646183 0.00475820676556288 0.0512201949962562 GO:0015149 hexose transmembrane transporter activity 2/82 24/18639 0.0833333333333333 18.9420731707317 0.00495560987748177 0.0512201949962562 GO:0055056 D-glucose transmembrane transporter activity 2/82 24/18639 0.0833333333333333 18.9420731707317 0.00495560987748177 0.0512201949962562 GO:0046332 SMAD binding 3/82 79/18639 0.0379746835443038 8.63183081197901 0.00510311905866759 0.0512201949962562 GO:0004866 endopeptidase inhibitor activity 4/82 161/18639 0.0248447204968944 5.64732616270262 0.00556389105752873 0.0524141150684253 GO:0015145 monosaccharide transmembrane transporter activity 2/82 26/18639 0.0769230769230769 17.484990619137 0.00580230056108029 0.0524141150684253 GO:0070412 R-SMAD binding 2/82 26/18639 0.0769230769230769 17.484990619137 0.00580230056108029 0.0524141150684253 GO:0030414 peptidase inhibitor activity 4/82 169/18639 0.0236686390532544 5.3799971135806 0.00659089000395917 0.0551054385871601 GO:0051119 sugar transmembrane transporter activity 2/82 28/18639 0.0714285714285714 16.23606271777 0.00671025635932208 0.0551054385871601 GO:0097718 disordered domain specific binding 2/82 28/18639 0.0714285714285714 16.23606271777 0.00671025635932208 0.0551054385871601 GO:0005126 cytokine receptor binding 5/82 275/18639 0.0181818181818182 4.13281596452328 0.00730595070356254 0.0578010107667709 GO:0001968 fibronectin binding 2/82 30/18639 0.0666666666666667 15.1536585365854 0.00767836305388838 0.0578010107667709 GO:0048019 receptor antagonist activity 2/82 30/18639 0.0666666666666667 15.1536585365854 0.00767836305388838 0.0578010107667709 GO:0004867 serine-type endopeptidase inhibitor activity 3/82 95/18639 0.0315789473684211 7.17804878048781 0.0084949187981399 0.0614325551231984 GO:0019207 kinase regulator activity 5/82 287/18639 0.0174216027874564 3.96001529701708 0.00869839834774084 0.0614325551231984 GO:0061135 endopeptidase regulator activity 4/82 184/18639 0.0217391304347826 4.94141039236479 0.00884084741625365 0.0614325551231984 GO:0090482 vitamin transmembrane transporter activity 2/82 34/18639 0.0588235294117647 13.37087517934 0.00979064423206408 0.0663316146722342 GO:0005501 retinoid binding 2/82 38/18639 0.0526315789473684 11.9634146341463 0.0121305159803576 0.0782707102542119 GO:0019840 isoprenoid binding 2/82 38/18639 0.0526315789473684 11.9634146341463 0.0121305159803576 0.0782707102542119 GO:0015144 carbohydrate transmembrane transporter activity 2/82 40/18639 0.05 11.365243902439 0.013383163182741 0.0843450516865772 GO:0042056 chemoattractant activity 2/82 42/18639 0.0476190476190476 10.8240418118467 0.0146895733157494 0.0897551138775263 GO:1990782 protein tyrosine kinase binding 3/82 117/18639 0.0256410256410256 5.82833020637899 0.0149039856992202 0.0897551138775263 GO:0048156 tau protein binding 2/82 43/18639 0.0465116279069767 10.5723199092456 0.0153626212775109 0.0905058775262055 GO:0030547 signaling receptor inhibitor activity 2/82 44/18639 0.0454545454545455 10.3320399113082 0.0160487297987738 0.0919996686620956 GO:0051082 unfolded protein binding 3/82 121/18639 0.0247933884297521 5.63565813344084 0.016295144264873 0.0919996686620956 GO:0061134 peptidase regulator activity 4/82 226/18639 0.0176991150442478 4.02309518670408 0.017639020821894 0.0975545845455771 GO:0042826 histone deacetylase binding 3/82 127/18639 0.0236220472440945 5.36940656808143 0.0185145332853269 0.100348770406472 GO:0005179 hormone activity 3/82 132/18639 0.0227272727272727 5.1660199556541 0.0204861806395276 0.108857940261019 GO:0019838 growth factor binding 3/82 136/18639 0.0220588235294118 5.01407819225251 0.0221436848986648 0.113225256746003 GO:0044325 transmembrane transporter binding 3/82 136/18639 0.0220588235294118 5.01407819225251 0.0221436848986648 0.113225256746003 GO:0030295 protein kinase activator activity 3/82 139/18639 0.0215827338129496 4.90586067731181 0.0234336378968935 0.117602145741817 GO:0140104 molecular carrier activity 4/82 249/18639 0.0160642570281124 3.65148398471936 0.0241700778487092 0.119092565400003 GO:0170055 lipid transmembrane transporter activity 2/82 56/18639 0.0357142857142857 8.11803135888502 0.0252560736009266 0.121880397783319 GO:0019955 cytokine binding 3/82 144/18639 0.0208333333333333 4.73551829268293 0.0256727453613606 0.121880397783319 GO:0019887 protein kinase regulator activity 4/82 255/18639 0.0156862745098039 3.56556671449067 0.0260851035846218 0.121880397783319 GO:0140375 immune receptor activity 3/82 156/18639 0.0192307692307692 4.37124765478424 0.0315003089062724 0.14468785955254 GO:0004857 enzyme inhibitor activity 5/82 416/18639 0.0120192307692308 2.73202978424015 0.0364450822930072 0.164610288356749 GO:0008028 monocarboxylic acid transmembrane transporter activity 2/82 70/18639 0.0285714285714286 6.49442508710801 0.0380787423908284 0.169169494883844 GO:0008401 retinoic acid 4-hydroxylase activity 1/82 10/18639 0.1 22.730487804878 0.0431431740009239 0.182699666033912 GO:0032395 MHC class II receptor activity 1/82 10/18639 0.1 22.730487804878 0.0431431740009239 0.182699666033912 GO:0044183 protein folding chaperone 2/82 75/18639 0.0266666666666667 6.06146341463415 0.0431467845984146 0.182699666033912 GO:0001851 complement component C3b binding 1/82 11/18639 0.0909090909090909 20.6640798226164 0.0473550082234764 0.194022932369514 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding 1/82 11/18639 0.0909090909090909 20.6640798226164 0.0473550082234764 0.194022932369514 GO:0005165 neurotrophin receptor binding 1/82 12/18639 0.0833333333333333 18.9420731707317 0.0515485281572141 0.194022932369514 GO:0015166 polyol transmembrane transporter activity 1/82 12/18639 0.0833333333333333 18.9420731707317 0.0515485281572141 0.194022932369514 GO:0031543 peptidyl-proline dioxygenase activity 1/82 12/18639 0.0833333333333333 18.9420731707317 0.0515485281572141 0.194022932369514 GO:0035014 phosphatidylinositol 3-kinase regulator activity 1/82 12/18639 0.0833333333333333 18.9420731707317 0.0515485281572141 0.194022932369514 GO:0042301 phosphate ion binding 1/82 12/18639 0.0833333333333333 18.9420731707317 0.0515485281572141 0.194022932369514 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 1/82 12/18639 0.0833333333333333 18.9420731707317 0.0515485281572141 0.194022932369514 GO:0031432 titin binding 1/82 13/18639 0.0769230769230769 17.484990619137 0.0557238124590937 0.19869938390019 GO:0039706 co-receptor binding 1/82 13/18639 0.0769230769230769 17.484990619137 0.0557238124590937 0.19869938390019 GO:0043560 insulin receptor substrate binding 1/82 13/18639 0.0769230769230769 17.484990619137 0.0557238124590937 0.19869938390019 GO:0086080 protein binding involved in heterotypic cell-cell adhesion 1/82 13/18639 0.0769230769230769 17.484990619137 0.0557238124590937 0.19869938390019 GO:0004197 cysteine-type endopeptidase activity 2/82 88/18639 0.0227272727272727 5.1660199556541 0.0573982527153686 0.20201203228396 GO:0005161 platelet-derived growth factor receptor binding 1/82 14/18639 0.0714285714285714 16.23606271777 0.0598809394524553 0.205414361919182 GO:0043176 amine binding 1/82 14/18639 0.0714285714285714 16.23606271777 0.0598809394524553 0.205414361919182 GO:0003714 transcription corepressor activity 3/82 204/18639 0.0147058823529412 3.34271879483501 0.061041848818473 0.206779262872577 GO:0005402 carbohydrate:monoatomic cation symporter activity 1/82 15/18639 0.0666666666666667 15.1536585365854 0.0640199871284233 0.210450360730355 GO:0008242 omega peptidase activity 1/82 15/18639 0.0666666666666667 15.1536585365854 0.0640199871284233 0.210450360730355 GO:0042562 hormone binding 2/82 94/18639 0.0212765957446809 4.83627400103788 0.0644552765336511 0.210450360730355 GO:0004896 cytokine receptor activity 2/82 96/18639 0.0208333333333333 4.73551829268293 0.0668697292994185 0.212255402102494 GO:0005159 insulin-like growth factor receptor binding 1/82 16/18639 0.0625 14.2065548780488 0.0681410331472951 0.212255402102494 GO:0005324 long-chain fatty acid transmembrane transporter activity 1/82 16/18639 0.0625 14.2065548780488 0.0681410331472951 0.212255402102494 GO:0019841 retinol binding 1/82 16/18639 0.0625 14.2065548780488 0.0681410331472951 0.212255402102494 GO:0043130 ubiquitin binding 2/82 100/18639 0.02 4.54609756097561 0.0717875543954283 0.215144680896931 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 1/82 17/18639 0.0588235294117647 13.37087517934 0.0722441548399289 0.215144680896931 GO:0038191 neuropilin binding 1/82 17/18639 0.0588235294117647 13.37087517934 0.0722441548399289 0.215144680896931 GO:0051787 misfolded protein binding 1/82 17/18639 0.0588235294117647 13.37087517934 0.0722441548399289 0.215144680896931 GO:0031690 adrenergic receptor binding 1/82 18/18639 0.0555555555555556 12.6280487804878 0.076329429209123 0.220048722870792 GO:0070064 proline-rich region binding 1/82 18/18639 0.0555555555555556 12.6280487804878 0.076329429209123 0.220048722870792 GO:0015245 fatty acid transmembrane transporter activity 1/82 19/18639 0.0526315789473684 11.9634146341463 0.0803969329309879 0.220048722870792 GO:0015355 secondary active monocarboxylate transmembrane transporter activity 1/82 19/18639 0.0526315789473684 11.9634146341463 0.0803969329309879 0.220048722870792 GO:0016918 retinal binding 1/82 19/18639 0.0526315789473684 11.9634146341463 0.0803969329309879 0.220048722870792 GO:0030506 ankyrin binding 1/82 19/18639 0.0526315789473684 11.9634146341463 0.0803969329309879 0.220048722870792 GO:0042834 peptidoglycan binding 1/82 19/18639 0.0526315789473684 11.9634146341463 0.0803969329309879 0.220048722870792 GO:0043395 heparan sulfate proteoglycan binding 1/82 19/18639 0.0526315789473684 11.9634146341463 0.0803969329309879 0.220048722870792 GO:0001972 retinoic acid binding 1/82 20/18639 0.05 11.365243902439 0.0844467423563185 0.220048722870792 GO:0016004 phospholipase activator activity 1/82 20/18639 0.05 11.365243902439 0.0844467423563185 0.220048722870792 GO:0031418 L-ascorbic acid binding 1/82 20/18639 0.05 11.365243902439 0.0844467423563185 0.220048722870792 GO:0042288 MHC class I protein binding 1/82 20/18639 0.05 11.365243902439 0.0844467423563185 0.220048722870792 GO:0052745 inositol phosphate phosphatase activity 1/82 20/18639 0.05 11.365243902439 0.0844467423563185 0.220048722870792 GO:0001846 opsonin binding 1/82 21/18639 0.0476190476190476 10.8240418118467 0.0884789335119542 0.222016583164256 GO:0019200 carbohydrate kinase activity 1/82 21/18639 0.0476190476190476 10.8240418118467 0.0884789335119542 0.222016583164256 GO:0070182 DNA polymerase binding 1/82 21/18639 0.0476190476190476 10.8240418118467 0.0884789335119542 0.222016583164256 GO:0072542 protein phosphatase activator activity 1/82 21/18639 0.0476190476190476 10.8240418118467 0.0884789335119542 0.222016583164256 GO:0015294 solute:monoatomic cation symporter activity 2/82 116/18639 0.0172413793103448 3.9190496215307 0.0925455459585135 0.230090302337222 GO:0004602 glutathione peroxidase activity 1/82 23/18639 0.0434782608695652 9.88282078472959 0.0964907635098626 0.233099259894303 GO:0005158 insulin receptor binding 1/82 23/18639 0.0434782608695652 9.88282078472959 0.0964907635098626 0.233099259894303 GO:0032182 ubiquitin-like protein binding 2/82 120/18639 0.0166666666666667 3.78841463414634 0.0979809454511722 0.233099259894303 GO:0015295 solute:proton symporter activity 1/82 24/18639 0.0416666666666667 9.47103658536585 0.100470552798227 0.233099259894303 GO:0030215 semaphorin receptor binding 1/82 24/18639 0.0416666666666667 9.47103658536585 0.100470552798227 0.233099259894303 GO:0035035 histone acetyltransferase binding 1/82 24/18639 0.0416666666666667 9.47103658536585 0.100470552798227 0.233099259894303 GO:0060229 lipase activator activity 1/82 24/18639 0.0416666666666667 9.47103658536585 0.100470552798227 0.233099259894303 GO:0001848 complement binding 1/82 25/18639 0.04 9.09219512195122 0.104433024711767 0.233099259894303 GO:0019211 phosphatase activator activity 1/82 25/18639 0.04 9.09219512195122 0.104433024711767 0.233099259894303 GO:0019706 protein-cysteine S-palmitoyltransferase activity 1/82 25/18639 0.04 9.09219512195122 0.104433024711767 0.233099259894303 GO:0019707 protein-cysteine S-acyltransferase activity 1/82 25/18639 0.04 9.09219512195122 0.104433024711767 0.233099259894303 GO:0004435 phosphatidylinositol phospholipase C activity 1/82 26/18639 0.0384615384615385 8.74249530956848 0.108378253677794 0.233099259894303 GO:0008198 ferrous iron binding 1/82 26/18639 0.0384615384615385 8.74249530956848 0.108378253677794 0.233099259894303 GO:0030247 polysaccharide binding 1/82 26/18639 0.0384615384615385 8.74249530956848 0.108378253677794 0.233099259894303 GO:0043548 phosphatidylinositol 3-kinase binding 1/82 26/18639 0.0384615384615385 8.74249530956848 0.108378253677794 0.233099259894303 GO:0050750 low-density lipoprotein particle receptor binding 1/82 26/18639 0.0384615384615385 8.74249530956848 0.108378253677794 0.233099259894303 GO:0052742 phosphatidylinositol kinase activity 1/82 26/18639 0.0384615384615385 8.74249530956848 0.108378253677794 0.233099259894303 GO:0004364 glutathione transferase activity 1/82 27/18639 0.037037037037037 8.41869918699187 0.112306313807726 0.239645756235384 GO:0045499 chemorepellent activity 1/82 28/18639 0.0357142857142857 8.11803135888502 0.116217278898408 0.242017229159501 GO:0051087 protein-folding chaperone binding 2/82 134/18639 0.0149253731343284 3.39261012013105 0.117671912373892 0.242017229159501 GO:0003785 actin monomer binding 1/82 29/18639 0.0344827586206897 7.8380992430614 0.120111222433431 0.242017229159501 GO:0004629 phospholipase C activity 1/82 29/18639 0.0344827586206897 7.8380992430614 0.120111222433431 0.242017229159501 GO:0016417 S-acyltransferase activity 1/82 29/18639 0.0344827586206897 7.8380992430614 0.120111222433431 0.242017229159501 GO:0043236 laminin binding 1/82 29/18639 0.0344827586206897 7.8380992430614 0.120111222433431 0.242017229159501 GO:0051861 glycolipid binding 1/82 29/18639 0.0344827586206897 7.8380992430614 0.120111222433431 0.242017229159501 GO:0002020 protease binding 2/82 136/18639 0.0147058823529412 3.34271879483501 0.120562088326688 0.242017229159501 GO:0016769 transferase activity, transferring nitrogenous groups 1/82 30/18639 0.0333333333333333 7.57682926829268 0.12398821758445 0.245261364710847 GO:0031210 phosphatidylcholine binding 1/82 30/18639 0.0333333333333333 7.57682926829268 0.12398821758445 0.245261364710847 GO:0070325 lipoprotein particle receptor binding 1/82 31/18639 0.032258064516129 7.3324154209284 0.127848337212483 0.25106448829408 GO:0042910 xenobiotic transmembrane transporter activity 1/82 32/18639 0.03125 7.10327743902439 0.131691653869222 0.255037798509338 GO:0019903 protein phosphatase binding 2/82 144/18639 0.0138888888888889 3.15701219512195 0.132294282606691 0.255037798509338 GO:0015293 symporter activity 2/82 146/18639 0.0136986301369863 3.11376545272302 0.135267646353195 0.255037798509338 GO:0019956 chemokine binding 1/82 33/18639 0.0303030303030303 6.8880266075388 0.13551823979832 0.255037798509338 GO:0030296 protein tyrosine kinase activator activity 1/82 33/18639 0.0303030303030303 6.8880266075388 0.13551823979832 0.255037798509338 GO:0140311 protein sequestering activity 1/82 33/18639 0.0303030303030303 6.8880266075388 0.13551823979832 0.255037798509338 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 1/82 34/18639 0.0294117647058824 6.68543758967001 0.139328166936691 0.260399539585126 GO:0019842 vitamin binding 2/82 150/18639 0.0133333333333333 3.03073170731707 0.141259275695942 0.262200436394523 GO:0004190 aspartic-type endopeptidase activity 1/82 36/18639 0.0277777777777778 6.3140243902439 0.146898331062906 0.2689573290404 GO:0016409 palmitoyltransferase activity 1/82 36/18639 0.0277777777777778 6.3140243902439 0.146898331062906 0.2689573290404 GO:0031625 ubiquitin protein ligase binding 3/82 302/18639 0.00993377483443709 2.25799547730577 0.147876907848781 0.2689573290404 GO:0043394 proteoglycan binding 1/82 37/18639 0.027027027027027 6.14337508239947 0.150658710402413 0.270387486881152 GO:0070001 aspartic-type peptidase activity 1/82 37/18639 0.027027027027027 6.14337508239947 0.150658710402413 0.270387486881152 GO:0005109 frizzled binding 1/82 38/18639 0.0263157894736842 5.98170731707317 0.154402715657063 0.275218272348673 GO:0099106 ion channel regulator activity 2/82 160/18639 0.0125 2.84131097560976 0.15647810937324 0.275218272348673 GO:0005178 integrin binding 2/82 161/18639 0.0124223602484472 2.82366308135131 0.158017249266602 0.275218272348673 GO:0008083 growth factor activity 2/82 162/18639 0.0123456790123457 2.80623306233062 0.159559303471958 0.275218272348673 GO:0015036 disulfide oxidoreductase activity 1/82 40/18639 0.025 5.68262195121951 0.16184188530223 0.275218272348673 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 1/82 40/18639 0.025 5.68262195121951 0.16184188530223 0.275218272348673 GO:0050997 quaternary ammonium group binding 1/82 40/18639 0.025 5.68262195121951 0.16184188530223 0.275218272348673 GO:0140662 ATP-dependent protein folding chaperone 1/82 40/18639 0.025 5.68262195121951 0.16184188530223 0.275218272348673 GO:0001530 lipopolysaccharide binding 1/82 41/18639 0.024390243902439 5.54402141582391 0.165537189641453 0.275218272348673 GO:0001727 lipid kinase activity 1/82 41/18639 0.024390243902439 5.54402141582391 0.165537189641453 0.275218272348673 GO:0017080 sodium channel regulator activity 1/82 41/18639 0.024390243902439 5.54402141582391 0.165537189641453 0.275218272348673 GO:0042287 MHC protein binding 1/82 41/18639 0.024390243902439 5.54402141582391 0.165537189641453 0.275218272348673 GO:0016247 channel regulator activity 2/82 168/18639 0.0119047619047619 2.70601045296167 0.168869808812274 0.277492917188638 GO:0044389 ubiquitin-like protein ligase binding 3/82 322/18639 0.0093167701863354 2.11774731101348 0.168953252162824 0.277492917188638 GO:0141108 transporter regulator activity 2/82 170/18639 0.0117647058823529 2.67417503586801 0.17199420434048 0.280785719134158 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 1/82 46/18639 0.0217391304347826 4.94141039236479 0.183773678828457 0.295991853695469 GO:0030291 protein serine/threonine kinase inhibitor activity 1/82 46/18639 0.0217391304347826 4.94141039236479 0.183773678828457 0.295991853695469 GO:0005319 lipid transporter activity 2/82 178/18639 0.0112359550561798 2.55398739380652 0.184585325736289 0.295991853695469 GO:0001784 phosphotyrosine residue binding 1/82 47/18639 0.0212765957446809 4.83627400103788 0.187373450696153 0.298695324345044 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 2/82 181/18639 0.0110497237569061 2.51165611103625 0.189342049866167 0.299130018354761 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 1/82 48/18639 0.0208333333333333 4.73551829268293 0.190957539392523 0.299130018354761 GO:0016879 ligase activity, forming carbon-nitrogen bonds 1/82 48/18639 0.0208333333333333 4.73551829268293 0.190957539392523 0.299130018354761 GO:0016763 pentosyltransferase activity 1/82 49/18639 0.0204081632653061 4.63887506222001 0.194526012404723 0.302968674492414 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 3/82 349/18639 0.00859598853868195 1.95391012649382 0.198683604070593 0.303784199696559 GO:0008234 cysteine-type peptidase activity 2/82 187/18639 0.0106951871657754 2.43106821442546 0.198905575368133 0.303784199696559 GO:0031406 carboxylic acid binding 2/82 187/18639 0.0106951871657754 2.43106821442546 0.198905575368133 0.303784199696559 GO:0046943 carboxylic acid transmembrane transporter activity 2/82 188/18639 0.0106382978723404 2.41813700051894 0.200505451685131 0.303784199696559 GO:0005342 organic acid transmembrane transporter activity 2/82 189/18639 0.0105820105820106 2.40534262485482 0.202106909638393 0.303784199696559 GO:0043177 organic acid binding 2/82 189/18639 0.0105820105820106 2.40534262485482 0.202106909638393 0.303784199696559 GO:0019902 phosphatase binding 2/82 190/18639 0.0105263157894737 2.39268292682927 0.203709905057775 0.303784199696559 GO:0005080 protein kinase C binding 1/82 52/18639 0.0192307692307692 4.37124765478424 0.205138407913175 0.303784199696559 GO:0030159 signaling receptor complex adaptor activity 1/82 52/18639 0.0192307692307692 4.37124765478424 0.205138407913175 0.303784199696559 GO:0017046 peptide hormone binding 1/82 53/18639 0.0188679245283019 4.28877128393925 0.208645087342405 0.307297927553216 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 1/82 54/18639 0.0185185185185185 4.20934959349593 0.212136484245339 0.307427739200465 GO:0050661 NADP binding 1/82 54/18639 0.0185185185185185 4.20934959349593 0.212136484245339 0.307427739200465 GO:0051287 NAD binding 1/82 54/18639 0.0185185185185185 4.20934959349593 0.212136484245339 0.307427739200465 GO:0098632 cell-cell adhesion mediator activity 1/82 55/18639 0.0181818181818182 4.13281596452328 0.215612664406323 0.309158899757214 GO:0140313 molecular sequestering activity 1/82 55/18639 0.0181818181818182 4.13281596452328 0.215612664406323 0.309158899757214 GO:0015459 potassium channel regulator activity 1/82 59/18639 0.0169491525423729 3.85262505167425 0.229366523554679 0.325436271640409 GO:0045309 protein phosphorylated amino acid binding 1/82 59/18639 0.0169491525423729 3.85262505167425 0.229366523554679 0.325436271640409 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 1/82 60/18639 0.0166666666666667 3.78841463414634 0.232767597024459 0.328541764550148 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 1/82 61/18639 0.0163934426229508 3.72630947620952 0.236153842626698 0.33159425570899 GO:0019843 rRNA binding 1/82 65/18639 0.0153846153846154 3.49699812382739 0.249551819320041 0.348600737297583 GO:0050840 extracellular matrix binding 1/82 67/18639 0.0149253731343284 3.39261012013105 0.256163487750883 0.35600156502815 GO:0002039 p53 binding 1/82 69/18639 0.0144927536231884 3.29427359490986 0.262717609633386 0.36140341223679 GO:0008080 N-acetyltransferase activity 1/82 69/18639 0.0144927536231884 3.29427359490986 0.262717609633386 0.36140341223679 GO:0097110 scaffold protein binding 1/82 70/18639 0.0142857142857143 3.24721254355401 0.265973245390525 0.363592639189307 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 2/82 229/18639 0.00873362445414847 1.98519544147407 0.266992380806908 0.363592639189307 GO:0005518 collagen binding 1/82 72/18639 0.0138888888888889 3.15701219512195 0.272441973778474 0.369158874469832 GO:0043539 protein serine/threonine kinase activator activity 1/82 73/18639 0.0136986301369863 3.11376545272302 0.275655188522383 0.371654507908288 GO:0048029 monosaccharide binding 1/82 74/18639 0.0135135135135135 3.07168754119974 0.27885438460884 0.374106624896019 GO:0098631 cell adhesion mediator activity 1/82 76/18639 0.0131578947368421 2.99085365853659 0.28521096218822 0.380749609620727 GO:0005539 glycosaminoglycan binding 2/82 242/18639 0.00826446280991736 1.87855271114695 0.288200545600789 0.382854646361832 GO:0015370 solute:sodium symporter activity 1/82 79/18639 0.0126582278481013 2.87727693732634 0.29464219051851 0.38761181374037 GO:0033293 monocarboxylic acid binding 1/82 79/18639 0.0126582278481013 2.87727693732634 0.29464219051851 0.38761181374037 GO:0033218 amide binding 2/82 247/18639 0.00809716599190283 1.84052532833021 0.296345112118012 0.387945013424413 GO:0048306 calcium-dependent protein binding 1/82 80/18639 0.0125 2.84131097560976 0.297758534288848 0.387945013424413 GO:0030971 receptor tyrosine kinase binding 1/82 81/18639 0.0123456790123457 2.80623306233062 0.300861276903661 0.390111990626278 GO:0001540 amyloid-beta binding 1/82 83/18639 0.0120481927710843 2.73861298853952 0.307026192945059 0.396209991848148 GO:0004860 protein kinase inhibitor activity 1/82 84/18639 0.0119047619047619 2.70601045296167 0.310088482887854 0.397516254460547 GO:0003713 transcription coactivator activity 2/82 256/18639 0.0078125 1.7758193597561 0.310972125260649 0.397516254460547 GO:0008081 phosphoric diester hydrolase activity 1/82 87/18639 0.0114942528735632 2.61269974768713 0.319195374304116 0.40611242458411 GO:0019210 kinase inhibitor activity 1/82 90/18639 0.0111111111111111 2.52560975609756 0.328183500829384 0.415596863199828 GO:0008514 organic anion transmembrane transporter activity 2/82 269/18639 0.00743494423791822 1.68999909329948 0.33199183684813 0.41846412923648 GO:0043178 alcohol binding 1/82 92/18639 0.0108695652173913 2.4707051961824 0.334110361025674 0.41899880893418 GO:0051213 dioxygenase activity 1/82 93/18639 0.010752688172043 2.4441384736428 0.337054392426757 0.41899880893418 GO:0051219 phosphoprotein binding 1/82 93/18639 0.010752688172043 2.4441384736428 0.337054392426757 0.41899880893418 GO:0016410 N-acyltransferase activity 1/82 94/18639 0.0106382978723404 2.41813700051894 0.33998556571593 0.420712732004644 GO:0016407 acetyltransferase activity 1/82 96/18639 0.0104166666666667 2.36775914634146 0.345809559593144 0.425974502953373 GO:0030246 carbohydrate binding 2/82 280/18639 0.00714285714285714 1.623606271777 0.349643935571172 0.42874889837008 GO:0015291 secondary active transmembrane transporter activity 2/82 287/18639 0.00696864111498258 1.58400611880683 0.360799385426947 0.440435285813976 GO:0140297 DNA-binding transcription factor binding 3/82 488/18639 0.00614754098360656 1.39736605357857 0.36360097725929 0.44186486474111 GO:0003712 transcription coregulator activity 3/82 495/18639 0.00606060606060606 1.37760532150776 0.372020893440092 0.448976646956135 GO:0004497 monooxygenase activity 1/82 106/18639 0.00943396226415094 2.14438564196963 0.374176668149915 0.448976646956135 GO:0005543 phospholipid binding 3/82 497/18639 0.00603621730382294 1.37206163812141 0.374423329195891 0.448976646956135 GO:0019888 protein phosphatase regulator activity 1/82 107/18639 0.00934579439252336 2.1243446546615 0.376945648520697 0.45001000330004 GO:0004843 cysteine-type deubiquitinase activity 1/82 108/18639 0.00925925925925926 2.10467479674797 0.37970252618211 0.45131309033049 GO:0004620 phospholipase activity 1/82 109/18639 0.00917431192660551 2.08536585365854 0.382447353382643 0.45259053609911 GO:0005200 structural constituent of cytoskeleton 1/82 112/18639 0.00892857142857143 2.02950783972125 0.390610051368161 0.458248155501176 GO:0043022 ribosome binding 1/82 112/18639 0.00892857142857143 2.02950783972125 0.390610051368161 0.458248155501176 GO:0101005 deubiquitinase activity 1/82 115/18639 0.00869565217391304 1.97656415694592 0.39866615487356 0.465683310218685 GO:0019208 phosphatase regulator activity 1/82 117/18639 0.00854700854700855 1.94277673545966 0.403978351136512 0.469863232437745 GO:0003697 single-stranded DNA binding 1/82 121/18639 0.00826446280991736 1.87855271114695 0.414464061027757 0.479998976660351 GO:0008528 G protein-coupled peptide receptor activity 1/82 122/18639 0.00819672131147541 1.86315473810476 0.417056886764646 0.480946452396677 GO:0019783 ubiquitin-like protein peptidase activity 1/82 127/18639 0.0078740157480315 1.78980218936048 0.429851863148581 0.493601080140955 GO:0001653 peptide receptor activity 1/82 128/18639 0.0078125 1.7758193597561 0.432377368076293 0.494406188812977 GO:0035591 signaling adaptor activity 1/82 129/18639 0.00775193798449612 1.7620533182076 0.434891821958728 0.495191948532837 GO:0016298 lipase activity 1/82 130/18639 0.00769230769230769 1.7484990619137 0.437395272558371 0.495958656331876 GO:0070851 growth factor receptor binding 1/82 139/18639 0.00719424460431655 1.63528689243727 0.459438960806441 0.51663053269106 GO:0140767 enzyme-substrate adaptor activity 1/82 139/18639 0.00719424460431655 1.63528689243727 0.459438960806441 0.51663053269106 GO:0042578 phosphoric ester hydrolase activity 2/82 363/18639 0.00550964187327824 1.25236847409796 0.476405520161193 0.53349543786646 GO:0046982 protein heterodimerization activity 2/82 369/18639 0.00542005420054201 1.23200475907198 0.485011424359281 0.54089751440891 GO:0015081 sodium ion transmembrane transporter activity 1/82 164/18639 0.00609756097560976 1.38600535395598 0.516293566270853 0.573424411718858 GO:0016874 ligase activity 1/82 167/18639 0.00598802395209581 1.36110705418431 0.522706059453471 0.57816069705977 GO:0005201 extracellular matrix structural constituent 1/82 168/18639 0.00595238095238095 1.35300522648084 0.52482483939743 0.57816069705977 GO:0008201 heparin binding 1/82 172/18639 0.00581395348837209 1.3215399886557 0.533207446903829 0.584393089071918 GO:0004175 endopeptidase activity 2/82 405/18639 0.00493827160493827 1.12249322493225 0.53479515162301 0.584393089071918 GO:0003735 structural constituent of ribosome 1/82 175/18639 0.00571428571428571 1.2988850174216 0.539398381887617 0.587056070247166 GO:0043021 ribonucleoprotein complex binding 1/82 177/18639 0.00564971751412429 1.28420835055808 0.543480539900029 0.589132905251632 GO:0015078 proton transmembrane transporter activity 1/82 185/18639 0.00540540540540541 1.22867501647989 0.559454835218884 0.604032909738317 GO:0140597 protein carrier chaperone 1/82 188/18639 0.00531914893617021 1.20906850025947 0.565301756569462 0.607923714406049 GO:0003779 actin binding 2/82 443/18639 0.00451467268623025 1.02620712437373 0.583734419688738 0.625264931761454 GO:0022804 active transmembrane transporter activity 2/82 457/18639 0.00437636761487965 0.994769706996851 0.600802414552116 0.641013599778045 GO:0000287 magnesium ion binding 1/82 230/18639 0.00434782608695652 0.988282078472959 0.639543631026335 0.679671858855438 GO:0016757 glycosyltransferase activity 1/82 267/18639 0.00374531835205993 0.851329131268841 0.694475494551941 0.735167418060844 GO:0005096 GTPase activator activity 1/82 271/18639 0.003690036900369 0.838763387633876 0.699894131016016 0.736425922186681 GO:0016791 phosphatase activity 1/82 273/18639 0.00366300366300366 0.832618600911284 0.702567739257474 0.736425922186681 GO:1901681 sulfur compound binding 1/82 275/18639 0.00363636363636364 0.826563192904656 0.70521781655043 0.736425922186681 GO:0008017 microtubule binding 1/82 276/18639 0.0036231884057971 0.823568398727466 0.706534095086853 0.736425922186681 GO:0035091 phosphatidylinositol binding 1/82 284/18639 0.00352112676056338 0.800369288904157 0.716857412773392 0.744323214029078 GO:0051020 GTPase binding 1/82 315/18639 0.00317460317460317 0.721602787456446 0.753580430023633 0.7794667806733 GO:0045296 cadherin binding 1/82 334/18639 0.0029940119760479 0.680553527092157 0.77371896189828 0.797254139446517 GO:0005525 GTP binding 1/82 378/18639 0.00264550264550265 0.601335656213705 0.814325076832836 0.835917029627646 GO:0015631 tubulin binding 1/82 385/18639 0.0025974025974026 0.590402280646183 0.820084312901922 0.838652259609135 GO:0019001 guanyl nucleotide binding 1/82 400/18639 0.0025 0.568262195121951 0.831837954154391 0.844299945976929 GO:0032561 guanyl ribonucleotide binding 1/82 400/18639 0.0025 0.568262195121951 0.831837954154391 0.844299945976929 GO:0016887 ATP hydrolysis activity 1/82 417/18639 0.00239808153477218 0.545095630812423 0.844243728429611 0.853694217926958 GO:0046873 metal ion transmembrane transporter activity 1/82 450/18639 0.00222222222222222 0.505121951219512 0.865800924620043 0.872238106215731 GO:0030695 GTPase regulator activity 1/82 489/18639 0.00204498977505112 0.464836151428999 0.887503566738809 0.888011815087427 GO:0060589 nucleoside-triphosphatase regulator activity 1/82 490/18639 0.00204081632653061 0.463887506222001 0.888011815087427 0.888011815087427