ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0005201 extracellular matrix structural constituent 17/269 168/18639 0.101190476190476 7.01148433351036 3.62285718506211e-10 2.02517716644972e-07 GO:0003823 antigen binding 13/269 174/18639 0.0747126436781609 5.17683630303807 1.52071054418313e-06 0.000425038597099185 GO:0034987 immunoglobulin receptor binding 5/269 19/18639 0.263157894736842 18.2342007434944 5.94402624413511e-06 0.00110757022349051 GO:0005178 integrin binding 11/269 161/18639 0.0683229813664596 4.7340968389942 2.27456708769965e-05 0.00317870750506026 GO:0008083 growth factor activity 10/269 162/18639 0.0617283950617284 4.27715819909128 0.000125284047793174 0.0140067565432768 GO:0031720 haptoglobin binding 3/269 10/18639 0.3 20.7869888475836 0.000330924843320138 0.0308311645693262 GO:0023026 MHC class II protein complex binding 4/269 27/18639 0.148148148148148 10.2651796778191 0.000573165092992591 0.0413405735566477 GO:0005125 cytokine activity 11/269 234/18639 0.047008547008547 3.25722047469259 0.000617491696834653 0.0413405735566477 GO:0016763 pentosyltransferase activity 5/269 49/18639 0.102040816326531 7.07040436992641 0.000684751627836676 0.0413405735566477 GO:0031994 insulin-like growth factor I binding 3/269 13/18639 0.230769230769231 15.9899914212182 0.000763780865492617 0.0413405735566477 GO:0019838 growth factor binding 8/269 136/18639 0.0588235294117647 4.07588016619287 0.000813499658538684 0.0413405735566477 GO:0005344 oxygen carrier activity 3/269 14/18639 0.214285714285714 14.8478491768455 0.000961749984506231 0.0413552493337679 GO:0008191 metalloendopeptidase inhibitor activity 3/269 14/18639 0.214285714285714 14.8478491768455 0.000961749984506231 0.0413552493337679 GO:0019903 protein phosphatase binding 8/269 144/18639 0.0555555555555556 3.84944237918216 0.00117852997850177 0.0470570184273207 GO:0004601 peroxidase activity 5/269 57/18639 0.087719298245614 6.07806691449814 0.00136925395707417 0.0510275308002976 GO:0016209 antioxidant activity 6/269 86/18639 0.0697674418604651 4.83418345292643 0.00153134547121181 0.0525914681079567 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 5/269 59/18639 0.0847457627118644 5.87203074790498 0.00159938275104698 0.0525914681079567 GO:0019902 phosphatase binding 9/269 190/18639 0.0473684210526316 3.282156133829 0.00180615000601006 0.0538462595878375 GO:0023023 MHC protein complex binding 4/269 37/18639 0.108108108108108 7.49080679192203 0.00192652091548614 0.0538462595878375 GO:0043394 proteoglycan binding 4/269 37/18639 0.108108108108108 7.49080679192203 0.00192652091548614 0.0538462595878375 GO:0005520 insulin-like growth factor binding 3/269 19/18639 0.157894736842105 10.9405204460967 0.00242730434403211 0.061675596741543 GO:0030506 ankyrin binding 3/269 19/18639 0.157894736842105 10.9405204460967 0.00242730434403211 0.061675596741543 GO:0003714 transcription corepressor activity 9/269 204/18639 0.0441176470588235 3.05691012464465 0.00291870788728136 0.0709372916952295 GO:0030020 extracellular matrix structural constituent conferring tensile strength 4/269 44/18639 0.0909090909090909 6.2990875295708 0.00365990715244104 0.0848797803321905 GO:0005518 collagen binding 5/269 72/18639 0.0694444444444444 4.8118029739777 0.00384191248110586 0.0848797803321905 GO:0042605 peptide antigen binding 4/269 45/18639 0.0888888888888889 6.15910780669145 0.00397211410209518 0.0848797803321905 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 3/269 23/18639 0.130434782608696 9.03782123807984 0.00425158112576267 0.0848797803321905 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 3/269 23/18639 0.130434782608696 9.03782123807984 0.00425158112576267 0.0848797803321905 GO:0098631 cell adhesion mediator activity 5/269 76/18639 0.0657894736842105 4.55855018587361 0.00484278948412298 0.0933489421249912 GO:0005080 protein kinase C binding 4/269 52/18639 0.0769230769230769 5.32999714040606 0.00667279762810212 0.124336462470303 GO:0097718 disordered domain specific binding 3/269 28/18639 0.107142857142857 7.42392458842273 0.00745874417187072 0.134497999744378 GO:0098632 cell-cell adhesion mediator activity 4/269 55/18639 0.0727272727272727 5.03927002365664 0.00812904533753924 0.142004260740139 GO:0032395 MHC class II receptor activity 2/269 10/18639 0.2 13.8579925650558 0.00865111773248041 0.142234553307546 GO:0070513 death domain binding 2/269 10/18639 0.2 13.8579925650558 0.00865111773248041 0.142234553307546 GO:0016504 peptidase activator activity 4/269 57/18639 0.0701754385964912 4.86245353159851 0.00920716847502018 0.147051633643894 GO:0048407 platelet-derived growth factor binding 2/269 11/18639 0.181818181818182 12.5981750591416 0.0104735496854183 0.16263095205969 GO:0015026 coreceptor activity 4/269 61/18639 0.0655737704918033 4.54360411969041 0.0116333258474495 0.173340212338381 GO:0019956 chemokine binding 3/269 33/18639 0.0909090909090909 6.2990875295708 0.0117834133611064 0.173340212338381 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 2/269 12/18639 0.166666666666667 11.5483271375465 0.0124494913000137 0.173981640917691 GO:0070008 serine-type exopeptidase activity 2/269 12/18639 0.166666666666667 11.5483271375465 0.0124494913000137 0.173981640917691 GO:0019825 oxygen binding 3/269 34/18639 0.0882352941176471 6.11382024928931 0.0127883237647823 0.174357877671056 GO:0005154 epidermal growth factor receptor binding 3/269 35/18639 0.0857142857142857 5.93913967073818 0.0138407756667616 0.184214133279042 GO:0140806 NAD+-protein-aspartate ADP-ribosyltransferase activity 2/269 13/18639 0.153846153846154 10.6599942808121 0.0145741659244721 0.189464157018137 GO:0016757 glycosyltransferase activity 9/269 267/18639 0.0337078651685393 2.3356167244476 0.0158130512104049 0.200897627877645 GO:0005161 platelet-derived growth factor receptor binding 2/269 14/18639 0.142857142857143 9.89856611789697 0.0168429019144663 0.20694965411763 GO:0061134 peptidase regulator activity 8/269 226/18639 0.0353982300884956 2.45274204691252 0.0171466020117316 0.20694965411763 GO:0019955 cytokine binding 6/269 144/18639 0.0416666666666667 2.88708178438662 0.0182597256159829 0.20694965411763 GO:0008028 monocarboxylic acid transmembrane transporter activity 4/269 70/18639 0.0571428571428571 3.95942644715879 0.018495005224734 0.20694965411763 GO:0005126 cytokine receptor binding 9/269 275/18639 0.0327272727272727 2.26767151064549 0.0187785222013478 0.20694965411763 GO:0044389 ubiquitin-like protein ligase binding 10/269 322/18639 0.031055900621118 2.15186219954282 0.018945554562304 0.20694965411763 GO:0008242 omega peptidase activity 2/269 15/18639 0.133333333333333 9.23866171003717 0.0192511306155935 0.20694965411763 GO:0051371 muscle alpha-actinin binding 2/269 15/18639 0.133333333333333 9.23866171003717 0.0192511306155935 0.20694965411763 GO:0140662 ATP-dependent protein folding chaperone 3/269 40/18639 0.075 5.19674721189591 0.0198245594994411 0.209092995475238 GO:0044183 protein folding chaperone 4/269 75/18639 0.0533333333333333 3.69546468401487 0.0231975015193628 0.235823736170704 GO:0045296 cadherin binding 10/269 334/18639 0.029940119760479 2.07454978518799 0.0236860380585283 0.235823736170704 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 2/269 17/18639 0.117647058823529 8.15176033238574 0.0244682946295185 0.235823736170704 GO:0019198 transmembrane receptor protein phosphatase activity 2/269 17/18639 0.117647058823529 8.15176033238574 0.0244682946295185 0.235823736170704 GO:0038191 neuropilin binding 2/269 17/18639 0.117647058823529 8.15176033238574 0.0244682946295185 0.235823736170704 GO:0070064 proline-rich region binding 2/269 18/18639 0.111111111111111 7.69888475836431 0.0272685899258446 0.251892859829471 GO:0098641 cadherin binding involved in cell-cell adhesion 2/269 18/18639 0.111111111111111 7.69888475836431 0.0272685899258446 0.251892859829471 GO:0003779 actin binding 12/269 443/18639 0.0270880361173815 1.87692901558317 0.0278363247758524 0.251892859829471 GO:0003712 transcription coregulator activity 13/269 495/18639 0.0262626262626263 1.81973639743156 0.0281250026163921 0.251892859829471 GO:0004180 carboxypeptidase activity 3/269 46/18639 0.0652173913043478 4.51891061903992 0.0286067939800268 0.251892859829471 GO:0001664 G protein-coupled receptor binding 9/269 297/18639 0.0303030303030303 2.09969584319027 0.0289910033758214 0.251892859829471 GO:0001618 virus receptor activity 4/269 81/18639 0.0493827160493827 3.42172655927303 0.0297194011520596 0.251892859829471 GO:0015355 secondary active monocarboxylate transmembrane transporter activity 2/269 19/18639 0.105263157894737 7.29368029739777 0.0301910941119402 0.251892859829471 GO:0043395 heparan sulfate proteoglycan binding 2/269 19/18639 0.105263157894737 7.29368029739777 0.0301910941119402 0.251892859829471 GO:0140272 exogenous protein binding 4/269 82/18639 0.0487804878048781 3.37999818659897 0.0309013236300762 0.25402705748842 GO:0019887 protein kinase regulator activity 8/269 255/18639 0.0313725490196078 2.17380275530286 0.0322042667889946 0.260901233841275 GO:0005006 epidermal growth factor receptor activity 3/269 50/18639 0.06 4.15739776951673 0.0354289633608467 0.278940711531173 GO:0048020 CCR chemokine receptor binding 3/269 50/18639 0.06 4.15739776951673 0.0354289633608467 0.278940711531173 GO:0001846 opsonin binding 2/269 21/18639 0.0952380952380952 6.59904407859798 0.0363864898593705 0.282500664324835 GO:0008093 cytoskeletal anchor activity 2/269 22/18639 0.0909090909090909 6.2990875295708 0.0396514890456174 0.295535765020002 GO:0030021 extracellular matrix structural constituent conferring compression resistance 2/269 22/18639 0.0909090909090909 6.2990875295708 0.0396514890456174 0.295535765020002 GO:0061133 endopeptidase activator activity 2/269 22/18639 0.0909090909090909 6.2990875295708 0.0396514890456174 0.295535765020002 GO:0004602 glutathione peroxidase activity 2/269 23/18639 0.0869565217391304 6.0252141587199 0.0430229088475083 0.312335143451391 GO:0017134 fibroblast growth factor binding 2/269 23/18639 0.0869565217391304 6.0252141587199 0.0430229088475083 0.312335143451391 GO:0140313 molecular sequestering activity 3/269 55/18639 0.0545454545454545 3.77945251774248 0.0450241573577117 0.322673127730267 GO:0030215 semaphorin receptor binding 2/269 24/18639 0.0833333333333333 5.77416356877323 0.0464970224758941 0.32489794455031 GO:0035035 histone acetyltransferase binding 2/269 24/18639 0.0833333333333333 5.77416356877323 0.0464970224758941 0.32489794455031 GO:0170055 lipid transmembrane transporter activity 3/269 56/18639 0.0535714285714286 3.71196229421136 0.0470826678089383 0.324928534632056 GO:0001848 complement binding 2/269 25/18639 0.08 5.54319702602231 0.0500701878392334 0.339278295499025 GO:0061135 endopeptidase regulator activity 6/269 184/18639 0.0326086956521739 2.25945530951996 0.0510165451701493 0.339278295499025 GO:0030295 protein kinase activator activity 5/269 139/18639 0.0359712230215827 2.49244470594528 0.0512138403433875 0.339278295499025 GO:0140297 DNA-binding transcription factor binding 12/269 488/18639 0.0245901639344262 1.70385154488391 0.0515897229291899 0.339278295499025 GO:0005160 transforming growth factor beta receptor binding 2/269 26/18639 0.0769230769230769 5.32999714040606 0.0537388458901396 0.341363805143046 GO:0050750 low-density lipoprotein particle receptor binding 2/269 26/18639 0.0769230769230769 5.32999714040606 0.0537388458901396 0.341363805143046 GO:0070412 R-SMAD binding 2/269 26/18639 0.0769230769230769 5.32999714040606 0.0537388458901396 0.341363805143046 GO:0004714 transmembrane receptor protein tyrosine kinase activity 3/269 60/18639 0.05 3.46449814126394 0.0557696160001961 0.349372077412676 GO:0019207 kinase regulator activity 8/269 287/18639 0.0278745644599303 1.93142753519941 0.0572251964110837 0.349372077412676 GO:0004364 glutathione transferase activity 2/269 27/18639 0.0740740740740741 5.13258983890954 0.0574995190017284 0.349372077412676 GO:0008320 protein transmembrane transporter activity 2/269 27/18639 0.0740740740740741 5.13258983890954 0.0574995190017284 0.349372077412676 GO:0045499 chemorepellent activity 2/269 28/18639 0.0714285714285714 4.94928305894849 0.061348809373256 0.364829621698405 GO:0051393 alpha-actinin binding 2/269 28/18639 0.0714285714285714 4.94928305894849 0.061348809373256 0.364829621698405 GO:0005539 glycosaminoglycan binding 7/269 242/18639 0.0289256198347107 2.00425512304525 0.0620707898645349 0.365105722655418 GO:0008236 serine-type peptidase activity 6/269 194/18639 0.0309278350515464 2.142988540988 0.06270151945424 0.365105722655418 GO:0019209 kinase activator activity 5/269 148/18639 0.0337837837837838 2.34087712247564 0.0636028099624964 0.366535781124077 GO:0004629 phospholipase C activity 2/269 29/18639 0.0689655172413793 4.7786181258813 0.0652833974645449 0.368620395784653 GO:0051861 glycolipid binding 2/269 29/18639 0.0689655172413793 4.7786181258813 0.0652833974645449 0.368620395784653 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 9/269 349/18639 0.0257879656160458 1.78684717887539 0.067229856765435 0.372487717465539 GO:0017171 serine hydrolase activity 6/269 198/18639 0.0303030303030303 2.09969584319027 0.0677834391042555 0.372487717465539 GO:0001968 fibronectin binding 2/269 30/18639 0.0666666666666667 4.61933085501859 0.0693000404587049 0.372487717465539 GO:0048019 receptor antagonist activity 2/269 30/18639 0.0666666666666667 4.61933085501859 0.0693000404587049 0.372487717465539 GO:0051721 protein phosphatase 2A binding 2/269 30/18639 0.0666666666666667 4.61933085501859 0.0693000404587049 0.372487717465539 GO:0042277 peptide binding 7/269 249/18639 0.0281124497991968 1.94791060151386 0.0699799291249251 0.372559813150792 GO:0005164 tumor necrosis factor receptor binding 2/269 31/18639 0.0645161290322581 4.47032018227605 0.0733955707526607 0.379890037506827 GO:0008327 methyl-CpG binding 2/269 31/18639 0.0645161290322581 4.47032018227605 0.0733955707526607 0.379890037506827 GO:0070325 lipoprotein particle receptor binding 2/269 31/18639 0.0645161290322581 4.47032018227605 0.0733955707526607 0.379890037506827 GO:0004222 metalloendopeptidase activity 4/269 110/18639 0.0363636363636364 2.51963501182832 0.0751286364617969 0.380349947469571 GO:0032934 sterol binding 3/269 68/18639 0.0441176470588235 3.05691012464465 0.075226524002847 0.380349947469571 GO:0140375 immune receptor activity 5/269 156/18639 0.032051282051282 2.22083214183586 0.0759090047159247 0.380349947469571 GO:0022884 macromolecule transmembrane transporter activity 2/269 32/18639 0.0625 4.33062267657993 0.0775668944750108 0.380349947469571 GO:0042910 xenobiotic transmembrane transporter activity 2/269 32/18639 0.0625 4.33062267657993 0.0775668944750108 0.380349947469571 GO:0043425 bHLH transcription factor binding 2/269 32/18639 0.0625 4.33062267657993 0.0775668944750108 0.380349947469571 GO:0005516 calmodulin binding 6/269 207/18639 0.0289855072463768 2.0084047195733 0.0800688381052765 0.387230288838478 GO:0004857 enzyme inhibitor activity 10/269 416/18639 0.0240384615384615 1.66562410637689 0.0803554803314195 0.387230288838478 GO:0051015 actin filament binding 6/269 209/18639 0.0287081339712919 1.98918553565394 0.082958063941492 0.396355194387128 GO:0001221 transcription coregulator binding 4/269 115/18639 0.0347826086956522 2.41008566348796 0.0852316751518878 0.403668926955114 GO:0042379 chemokine receptor binding 3/269 72/18639 0.0416666666666667 2.88708178438662 0.0859330989403552 0.403668926955114 GO:0043539 protein serine/threonine kinase activator activity 3/269 73/18639 0.0410958904109589 2.84753271884707 0.0887057556567131 0.413220978434188 GO:0017022 myosin binding 3/269 76/18639 0.0394736842105263 2.73513011152416 0.0972449356889259 0.440047214485392 GO:0005525 GTP binding 9/269 378/18639 0.0238095238095238 1.6497610196495 0.0981790276275747 0.440047214485392 GO:0042805 actinin binding 2/269 37/18639 0.0540540540540541 3.74540339596102 0.0994571090665465 0.440047214485392 GO:0019199 transmembrane receptor protein kinase activity 3/269 78/18639 0.0384615384615385 2.66499857020303 0.10311613916065 0.440047214485392 GO:0008201 heparin binding 5/269 172/18639 0.0290697674418605 2.01424310538601 0.104072512439946 0.440047214485392 GO:1901681 sulfur compound binding 7/269 275/18639 0.0254545454545455 1.76374450827982 0.104377650529992 0.440047214485392 GO:0046332 SMAD binding 3/269 79/18639 0.0379746835443038 2.63126441108654 0.106103460532555 0.440047214485392 GO:0042826 histone deacetylase binding 4/269 127/18639 0.031496062992126 2.18236103386705 0.111985992746487 0.440047214485392 GO:0015036 disulfide oxidoreductase activity 2/269 40/18639 0.05 3.46449814126394 0.113317986013428 0.440047214485392 GO:0061791 GTPase motor activity 2/269 40/18639 0.05 3.46449814126394 0.113317986013428 0.440047214485392 GO:1990606 membrane scission GTPase motor activity 2/269 40/18639 0.05 3.46449814126394 0.113317986013428 0.440047214485392 GO:0005319 lipid transporter activity 5/269 178/18639 0.0280898876404494 1.946347270373 0.115801211329651 0.440047214485392 GO:0140318 protein transporter activity 2/269 41/18639 0.0487804878048781 3.37999818659897 0.118043692233791 0.440047214485392 GO:0042056 chemoattractant activity 2/269 42/18639 0.0476190476190476 3.29952203929899 0.122818000962881 0.440047214485392 GO:0019001 guanyl nucleotide binding 9/269 400/18639 0.0225 1.55902416356877 0.126353889906048 0.440047214485392 GO:0032561 guanyl ribonucleotide binding 9/269 400/18639 0.0225 1.55902416356877 0.126353889906048 0.440047214485392 GO:0048156 tau protein binding 2/269 43/18639 0.0465116279069767 3.22278896861762 0.127638538917701 0.440047214485392 GO:0008237 metallopeptidase activity 5/269 184/18639 0.0271739130434783 1.88287942459997 0.128130690365091 0.440047214485392 GO:0051087 protein-folding chaperone binding 4/269 134/18639 0.0298507462686567 2.06835709926205 0.12911203087205 0.440047214485392 GO:0030547 signaling receptor inhibitor activity 2/269 44/18639 0.0454545454545455 3.1495437647854 0.132502990729505 0.440047214485392 GO:0002020 protease binding 4/269 136/18639 0.0294117647058824 2.03794008309644 0.13419551911217 0.440047214485392 GO:0016779 nucleotidyltransferase activity 4/269 136/18639 0.0294117647058824 2.03794008309644 0.13419551911217 0.440047214485392 GO:0044325 transmembrane transporter binding 4/269 136/18639 0.0294117647058824 2.03794008309644 0.13419551911217 0.440047214485392 GO:0005031 tumor necrosis factor receptor activity 1/269 10/18639 0.1 6.92899628252788 0.135330538819347 0.440047214485392 GO:0005131 growth hormone receptor binding 1/269 10/18639 0.1 6.92899628252788 0.135330538819347 0.440047214485392 GO:0005345 purine nucleobase transmembrane transporter activity 1/269 10/18639 0.1 6.92899628252788 0.135330538819347 0.440047214485392 GO:0005522 profilin binding 1/269 10/18639 0.1 6.92899628252788 0.135330538819347 0.440047214485392 GO:0008297 single-stranded DNA exodeoxyribonuclease activity 1/269 10/18639 0.1 6.92899628252788 0.135330538819347 0.440047214485392 GO:0016783 sulfurtransferase activity 1/269 10/18639 0.1 6.92899628252788 0.135330538819347 0.440047214485392 GO:0019531 oxalate transmembrane transporter activity 1/269 10/18639 0.1 6.92899628252788 0.135330538819347 0.440047214485392 GO:0030957 Tat protein binding 1/269 10/18639 0.1 6.92899628252788 0.135330538819347 0.440047214485392 GO:0043295 glutathione binding 1/269 10/18639 0.1 6.92899628252788 0.135330538819347 0.440047214485392 GO:0070097 delta-catenin binding 1/269 10/18639 0.1 6.92899628252788 0.135330538819347 0.440047214485392 GO:0008009 chemokine activity 2/269 45/18639 0.0444444444444444 3.07955390334572 0.137409097776908 0.440047214485392 GO:0051539 4 iron, 4 sulfur cluster binding 2/269 45/18639 0.0444444444444444 3.07955390334572 0.137409097776908 0.440047214485392 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 3/269 89/18639 0.0337078651685393 2.3356167244476 0.137726044012315 0.440047214485392 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 3/269 89/18639 0.0337078651685393 2.3356167244476 0.137726044012315 0.440047214485392 GO:0140793 histone H2AXY142 phosphatase activity 3/269 90/18639 0.0333333333333333 2.30966542750929 0.141049487576224 0.440047214485392 GO:0070851 growth factor receptor binding 4/269 139/18639 0.0287769784172662 1.99395576475622 0.141971493911337 0.440047214485392 GO:0004713 protein tyrosine kinase activity 4/269 140/18639 0.0285714285714286 1.97971322357939 0.144602600132023 0.440047214485392 GO:0043495 protein-membrane adaptor activity 2/269 47/18639 0.0425531914893617 2.94850905639484 0.147337519977934 0.440047214485392 GO:0043178 alcohol binding 3/269 92/18639 0.0326086956521739 2.25945530951996 0.14777611518022 0.440047214485392 GO:0001851 complement component C3b binding 1/269 11/18639 0.0909090909090909 6.2990875295708 0.14781623773274 0.440047214485392 GO:0002162 dystroglycan binding 1/269 11/18639 0.0909090909090909 6.2990875295708 0.14781623773274 0.440047214485392 GO:0005114 type II transforming growth factor beta receptor binding 1/269 11/18639 0.0909090909090909 6.2990875295708 0.14781623773274 0.440047214485392 GO:0008271 secondary active sulfate transmembrane transporter activity 1/269 11/18639 0.0909090909090909 6.2990875295708 0.14781623773274 0.440047214485392 GO:0008503 benzodiazepine receptor activity 1/269 11/18639 0.0909090909090909 6.2990875295708 0.14781623773274 0.440047214485392 GO:0015205 nucleobase transmembrane transporter activity 1/269 11/18639 0.0909090909090909 6.2990875295708 0.14781623773274 0.440047214485392 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 1/269 11/18639 0.0909090909090909 6.2990875295708 0.14781623773274 0.440047214485392 GO:0034511 U3 snoRNA binding 1/269 11/18639 0.0909090909090909 6.2990875295708 0.14781623773274 0.440047214485392 GO:0034713 type I transforming growth factor beta receptor binding 1/269 11/18639 0.0909090909090909 6.2990875295708 0.14781623773274 0.440047214485392 GO:0042608 T cell receptor binding 1/269 11/18639 0.0909090909090909 6.2990875295708 0.14781623773274 0.440047214485392 GO:0045294 alpha-catenin binding 1/269 11/18639 0.0909090909090909 6.2990875295708 0.14781623773274 0.440047214485392 GO:0097493 structural molecule activity conferring elasticity 1/269 11/18639 0.0909090909090909 6.2990875295708 0.14781623773274 0.440047214485392 GO:0140537 transcription regulator activator activity 1/269 11/18639 0.0909090909090909 6.2990875295708 0.14781623773274 0.440047214485392 GO:1900750 oligopeptide binding 1/269 11/18639 0.0909090909090909 6.2990875295708 0.14781623773274 0.440047214485392 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 2/269 48/18639 0.0416666666666667 2.88708178438662 0.152355591421148 0.440047214485392 GO:0016758 hexosyltransferase activity 5/269 197/18639 0.0253807106598985 1.75862849810352 0.15676968038283 0.440047214485392 GO:0001222 transcription corepressor binding 2/269 49/18639 0.0408163265306122 2.82816174797056 0.157406828491959 0.440047214485392 GO:0005004 GPI-linked ephrin receptor activity 2/269 49/18639 0.0408163265306122 2.82816174797056 0.157406828491959 0.440047214485392 GO:0005008 hepatocyte growth factor receptor activity 2/269 49/18639 0.0408163265306122 2.82816174797056 0.157406828491959 0.440047214485392 GO:0005009 insulin receptor activity 2/269 49/18639 0.0408163265306122 2.82816174797056 0.157406828491959 0.440047214485392 GO:0005011 macrophage colony-stimulating factor receptor activity 2/269 49/18639 0.0408163265306122 2.82816174797056 0.157406828491959 0.440047214485392 GO:0005018 platelet-derived growth factor alpha-receptor activity 2/269 49/18639 0.0408163265306122 2.82816174797056 0.157406828491959 0.440047214485392 GO:0005020 stem cell factor receptor activity 2/269 49/18639 0.0408163265306122 2.82816174797056 0.157406828491959 0.440047214485392 GO:0008288 boss receptor activity 2/269 49/18639 0.0408163265306122 2.82816174797056 0.157406828491959 0.440047214485392 GO:0036332 placental growth factor receptor activity 2/269 49/18639 0.0408163265306122 2.82816174797056 0.157406828491959 0.440047214485392 GO:0038062 protein tyrosine kinase collagen receptor activity 2/269 49/18639 0.0408163265306122 2.82816174797056 0.157406828491959 0.440047214485392 GO:0060175 brain-derived neurotrophic factor receptor activity 2/269 49/18639 0.0408163265306122 2.82816174797056 0.157406828491959 0.440047214485392 GO:0004000 adenosine deaminase activity 1/269 12/18639 0.0833333333333333 5.77416356877323 0.16012230559026 0.440047214485392 GO:0015166 polyol transmembrane transporter activity 1/269 12/18639 0.0833333333333333 5.77416356877323 0.16012230559026 0.440047214485392 GO:0035197 siRNA binding 1/269 12/18639 0.0833333333333333 5.77416356877323 0.16012230559026 0.440047214485392 GO:0097677 STAT family protein binding 1/269 12/18639 0.0833333333333333 5.77416356877323 0.16012230559026 0.440047214485392 GO:0140807 NAD+-protein-glutamate ADP-ribosyltransferase activity 1/269 12/18639 0.0833333333333333 5.77416356877323 0.16012230559026 0.440047214485392 GO:0140822 NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity 1/269 12/18639 0.0833333333333333 5.77416356877323 0.16012230559026 0.440047214485392 GO:0140829 bicarbonate:monoatomic anion antiporter activity 1/269 12/18639 0.0833333333333333 5.77416356877323 0.16012230559026 0.440047214485392 GO:0140844 NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity 1/269 12/18639 0.0833333333333333 5.77416356877323 0.16012230559026 0.440047214485392 GO:0140867 NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity 1/269 12/18639 0.0833333333333333 5.77416356877323 0.16012230559026 0.440047214485392 GO:0140900 chloride:bicarbonate antiporter activity 1/269 12/18639 0.0833333333333333 5.77416356877323 0.16012230559026 0.440047214485392 GO:0004896 cytokine receptor activity 3/269 96/18639 0.03125 2.16531133828996 0.161530720478994 0.440047214485392 GO:0005007 fibroblast growth factor receptor activity 2/269 50/18639 0.04 2.77159851301115 0.162489239539089 0.440047214485392 GO:0005017 platelet-derived growth factor receptor activity 2/269 50/18639 0.04 2.77159851301115 0.162489239539089 0.440047214485392 GO:0005019 platelet-derived growth factor beta-receptor activity 2/269 50/18639 0.04 2.77159851301115 0.162489239539089 0.440047214485392 GO:0032813 tumor necrosis factor receptor superfamily binding 2/269 50/18639 0.04 2.77159851301115 0.162489239539089 0.440047214485392 GO:0003713 transcription coactivator activity 6/269 256/18639 0.0234375 1.62398350371747 0.166475065233264 0.440047214485392 GO:0003743 translation initiation factor activity 2/269 51/18639 0.0392156862745098 2.71725344412858 0.167600883094225 0.440047214485392 GO:0005010 insulin-like growth factor receptor activity 2/269 51/18639 0.0392156862745098 2.71725344412858 0.167600883094225 0.440047214485392 GO:0005021 vascular endothelial growth factor receptor activity 2/269 51/18639 0.0392156862745098 2.71725344412858 0.167600883094225 0.440047214485392 GO:0005030 neurotrophin receptor activity 2/269 51/18639 0.0392156862745098 2.71725344412858 0.167600883094225 0.440047214485392 GO:0004725 protein tyrosine phosphatase activity 3/269 98/18639 0.0306122448979592 2.12112131097792 0.168548675464109 0.440047214485392 GO:0005035 death receptor activity 1/269 13/18639 0.0769230769230769 5.32999714040606 0.172251317229076 0.440047214485392 GO:0005172 vascular endothelial growth factor receptor binding 1/269 13/18639 0.0769230769230769 5.32999714040606 0.172251317229076 0.440047214485392 GO:0008035 high-density lipoprotein particle binding 1/269 13/18639 0.0769230769230769 5.32999714040606 0.172251317229076 0.440047214485392 GO:0008417 fucosyltransferase activity 1/269 13/18639 0.0769230769230769 5.32999714040606 0.172251317229076 0.440047214485392 GO:0031432 titin binding 1/269 13/18639 0.0769230769230769 5.32999714040606 0.172251317229076 0.440047214485392 GO:0039706 co-receptor binding 1/269 13/18639 0.0769230769230769 5.32999714040606 0.172251317229076 0.440047214485392 GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity 1/269 13/18639 0.0769230769230769 5.32999714040606 0.172251317229076 0.440047214485392 GO:0086080 protein binding involved in heterotypic cell-cell adhesion 1/269 13/18639 0.0769230769230769 5.32999714040606 0.172251317229076 0.440047214485392 GO:0004864 protein phosphatase inhibitor activity 2/269 53/18639 0.0377358490566038 2.61471557831241 0.177904346641668 0.440047214485392 GO:0005003 ephrin receptor activity 2/269 53/18639 0.0377358490566038 2.61471557831241 0.177904346641668 0.440047214485392 GO:0005005 transmembrane-ephrin receptor activity 2/269 53/18639 0.0377358490566038 2.61471557831241 0.177904346641668 0.440047214485392 GO:0016860 intramolecular oxidoreductase activity 2/269 53/18639 0.0377358490566038 2.61471557831241 0.177904346641668 0.440047214485392 GO:0038064 collagen receptor activity 2/269 53/18639 0.0377358490566038 2.61471557831241 0.177904346641668 0.440047214485392 GO:0008238 exopeptidase activity 3/269 102/18639 0.0294117647058824 2.03794008309644 0.182841049238007 0.440047214485392 GO:0003925 G protein activity 2/269 54/18639 0.037037037037037 2.56629491945477 0.183092525485499 0.440047214485392 GO:0015485 cholesterol binding 2/269 54/18639 0.037037037037037 2.56629491945477 0.183092525485499 0.440047214485392 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 2/269 54/18639 0.037037037037037 2.56629491945477 0.183092525485499 0.440047214485392 GO:0004065 arylsulfatase activity 1/269 14/18639 0.0714285714285714 4.94928305894849 0.184205810714815 0.440047214485392 GO:0008494 translation activator activity 1/269 14/18639 0.0714285714285714 4.94928305894849 0.184205810714815 0.440047214485392 GO:0008559 ABC-type xenobiotic transporter activity 1/269 14/18639 0.0714285714285714 4.94928305894849 0.184205810714815 0.440047214485392 GO:0019992 diacylglycerol binding 1/269 14/18639 0.0714285714285714 4.94928305894849 0.184205810714815 0.440047214485392 GO:0034236 protein kinase A catalytic subunit binding 1/269 14/18639 0.0714285714285714 4.94928305894849 0.184205810714815 0.440047214485392 GO:0044548 S100 protein binding 1/269 14/18639 0.0714285714285714 4.94928305894849 0.184205810714815 0.440047214485392 GO:0070742 C2H2 zinc finger domain binding 1/269 14/18639 0.0714285714285714 4.94928305894849 0.184205810714815 0.440047214485392 GO:0019212 phosphatase inhibitor activity 2/269 56/18639 0.0357142857142857 2.47464152947424 0.193533022391169 0.452716747588433 GO:0005402 carbohydrate:monoatomic cation symporter activity 1/269 15/18639 0.0666666666666667 4.61933085501859 0.19598828786476 0.452716747588433 GO:0005523 tropomyosin binding 1/269 15/18639 0.0666666666666667 4.61933085501859 0.19598828786476 0.452716747588433 GO:0015116 sulfate transmembrane transporter activity 1/269 15/18639 0.0666666666666667 4.61933085501859 0.19598828786476 0.452716747588433 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides 1/269 15/18639 0.0666666666666667 4.61933085501859 0.19598828786476 0.452716747588433 GO:0031386 protein tag activity 1/269 15/18639 0.0666666666666667 4.61933085501859 0.19598828786476 0.452716747588433 GO:0140161 monocarboxylate:sodium symporter activity 1/269 15/18639 0.0666666666666667 4.61933085501859 0.19598828786476 0.452716747588433 GO:0141047 molecular tag activity 1/269 15/18639 0.0666666666666667 4.61933085501859 0.19598828786476 0.452716747588433 GO:0003924 GTPase activity 7/269 331/18639 0.0211480362537764 1.46534664585182 0.203195650912478 0.462346928497465 GO:0004866 endopeptidase inhibitor activity 4/269 161/18639 0.0248447204968944 1.72148975963426 0.203828455535557 0.462346928497465 GO:0005496 steroid binding 3/269 108/18639 0.0277777777777778 1.92472118959108 0.204847494321469 0.462346928497465 GO:0005521 lamin binding 1/269 16/18639 0.0625 4.33062267657993 0.20760121476362 0.462346928497465 GO:0008142 oxysterol binding 1/269 16/18639 0.0625 4.33062267657993 0.20760121476362 0.462346928497465 GO:0008296 3'-5'-DNA exonuclease activity 1/269 16/18639 0.0625 4.33062267657993 0.20760121476362 0.462346928497465 GO:0015562 efflux transmembrane transporter activity 1/269 16/18639 0.0625 4.33062267657993 0.20760121476362 0.462346928497465 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 1/269 16/18639 0.0625 4.33062267657993 0.20760121476362 0.462346928497465 GO:0019841 retinol binding 1/269 16/18639 0.0625 4.33062267657993 0.20760121476362 0.462346928497465 GO:0070888 E-box binding 2/269 59/18639 0.0338983050847458 2.34881229916199 0.209329191795679 0.464345310372161 GO:0030246 carbohydrate binding 6/269 280/18639 0.0214285714285714 1.48478491768455 0.21902627723627 0.46924394944854 GO:0005092 GDP-dissociation inhibitor activity 1/269 17/18639 0.0588235294117647 4.07588016619287 0.219047022272002 0.46924394944854 GO:0008484 sulfuric ester hydrolase activity 1/269 17/18639 0.0588235294117647 4.07588016619287 0.219047022272002 0.46924394944854 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 1/269 17/18639 0.0588235294117647 4.07588016619287 0.219047022272002 0.46924394944854 GO:0045125 bioactive lipid receptor activity 1/269 17/18639 0.0588235294117647 4.07588016619287 0.219047022272002 0.46924394944854 GO:0051787 misfolded protein binding 1/269 17/18639 0.0588235294117647 4.07588016619287 0.219047022272002 0.46924394944854 GO:0070492 oligosaccharide binding 1/269 17/18639 0.0588235294117647 4.07588016619287 0.219047022272002 0.46924394944854 GO:0043022 ribosome binding 3/269 112/18639 0.0267857142857143 1.85598114710568 0.219841310411513 0.46924394944854 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 2/269 61/18639 0.0327868852459016 2.27180205984521 0.219931868972303 0.46924394944854 GO:0016836 hydro-lyase activity 2/269 61/18639 0.0327868852459016 2.27180205984521 0.219931868972303 0.46924394944854 GO:0030414 peptidase inhibitor activity 4/269 169/18639 0.0236686390532544 1.63999912012494 0.22804666721455 0.482031348774143 GO:0031690 adrenergic receptor binding 1/269 18/18639 0.0555555555555556 3.84944237918216 0.230328106527658 0.482031348774143 GO:0035615 clathrin adaptor activity 1/269 18/18639 0.0555555555555556 3.84944237918216 0.230328106527658 0.482031348774143 GO:0070628 proteasome binding 1/269 18/18639 0.0555555555555556 3.84944237918216 0.230328106527658 0.482031348774143 GO:0035401 histone H3Y41 kinase activity 3/269 115/18639 0.0260869565217391 1.80756424761597 0.231229766346077 0.482031348774143 GO:0140801 histone H2AXY142 kinase activity 3/269 115/18639 0.0260869565217391 1.80756424761597 0.231229766346077 0.482031348774143 GO:0004175 endopeptidase activity 8/269 405/18639 0.0197530864197531 1.36869062370921 0.232099942686524 0.482031348774143 GO:0015294 solute:monoatomic cation symporter activity 3/269 116/18639 0.0258620689655172 1.79198179720549 0.23505016267816 0.482031348774143 GO:0019208 phosphatase regulator activity 3/269 117/18639 0.0256410256410256 1.77666571346869 0.238881758104254 0.482031348774143 GO:1990782 protein tyrosine kinase binding 3/269 117/18639 0.0256410256410256 1.77666571346869 0.238881758104254 0.482031348774143 GO:0019843 rRNA binding 2/269 65/18639 0.0307692307692308 2.13199885616242 0.241257082344993 0.482031348774143 GO:0003756 protein disulfide isomerase activity 1/269 19/18639 0.0526315789473684 3.64684014869888 0.241446829439642 0.482031348774143 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 1/269 19/18639 0.0526315789473684 3.64684014869888 0.241446829439642 0.482031348774143 GO:0015245 fatty acid transmembrane transporter activity 1/269 19/18639 0.0526315789473684 3.64684014869888 0.241446829439642 0.482031348774143 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 1/269 19/18639 0.0526315789473684 3.64684014869888 0.241446829439642 0.482031348774143 GO:0016918 retinal binding 1/269 19/18639 0.0526315789473684 3.64684014869888 0.241446829439642 0.482031348774143 GO:0042834 peptidoglycan binding 1/269 19/18639 0.0526315789473684 3.64684014869888 0.241446829439642 0.482031348774143 GO:0070003 threonine-type peptidase activity 1/269 19/18639 0.0526315789473684 3.64684014869888 0.241446829439642 0.482031348774143 GO:0004252 serine-type endopeptidase activity 4/269 176/18639 0.0227272727272727 1.5747718823927 0.249800992165459 0.48653339730716 GO:0016500 protein-hormone receptor activity 2/269 67/18639 0.0298507462686567 2.06835709926205 0.251957896594426 0.48653339730716 GO:0050840 extracellular matrix binding 2/269 67/18639 0.0298507462686567 2.06835709926205 0.251957896594426 0.48653339730716 GO:0000339 RNA cap binding 1/269 20/18639 0.05 3.46449814126394 0.25240551917545 0.48653339730716 GO:0004745 all-trans-retinol dehydrogenase (NAD+) activity 1/269 20/18639 0.05 3.46449814126394 0.25240551917545 0.48653339730716 GO:0016004 phospholipase activator activity 1/269 20/18639 0.05 3.46449814126394 0.25240551917545 0.48653339730716 GO:0016505 peptidase activator activity involved in apoptotic process 1/269 20/18639 0.05 3.46449814126394 0.25240551917545 0.48653339730716 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 1/269 20/18639 0.05 3.46449814126394 0.25240551917545 0.48653339730716 GO:0043024 ribosomal small subunit binding 1/269 20/18639 0.05 3.46449814126394 0.25240551917545 0.48653339730716 GO:0052745 inositol phosphate phosphatase activity 1/269 20/18639 0.05 3.46449814126394 0.25240551917545 0.48653339730716 GO:0003697 single-stranded DNA binding 3/269 121/18639 0.0247933884297521 1.71793296261022 0.25430928174768 0.48684550855121 GO:0051082 unfolded protein binding 3/269 121/18639 0.0247933884297521 1.71793296261022 0.25430928174768 0.48684550855121 GO:0030145 manganese ion binding 2/269 68/18639 0.0294117647058824 2.03794008309644 0.257313392733565 0.48924553244239 GO:1990841 promoter-specific chromatin binding 2/269 68/18639 0.0294117647058824 2.03794008309644 0.257313392733565 0.48924553244239 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 1/269 21/18639 0.0476190476190476 3.29952203929899 0.263206470641254 0.493732943249869 GO:0015125 bile acid transmembrane transporter activity 1/269 21/18639 0.0476190476190476 3.29952203929899 0.263206470641254 0.493732943249869 GO:0070182 DNA polymerase binding 1/269 21/18639 0.0476190476190476 3.29952203929899 0.263206470641254 0.493732943249869 GO:0140312 cargo adaptor activity 1/269 21/18639 0.0476190476190476 3.29952203929899 0.263206470641254 0.493732943249869 GO:0097110 scaffold protein binding 2/269 70/18639 0.0285714285714286 1.97971322357939 0.268028581124787 0.501096912537646 GO:0031625 ubiquitin protein ligase binding 6/269 302/18639 0.0198675496688742 1.37662177798567 0.271406323595767 0.504179951906752 GO:0042578 phosphoric ester hydrolase activity 7/269 363/18639 0.0192837465564738 1.33617008203017 0.271481512565174 0.504179951906752 GO:0140035 ubiquitin-like protein reader activity 1/269 22/18639 0.0454545454545455 3.1495437647854 0.273851945955332 0.506898138374273 GO:0004022 alcohol dehydrogenase (NAD+) activity 1/269 23/18639 0.0434782608695652 3.01260707935995 0.284344174914778 0.516573901995472 GO:0005212 structural constituent of eye lens 1/269 23/18639 0.0434782608695652 3.01260707935995 0.284344174914778 0.516573901995472 GO:0016493 C-C chemokine receptor activity 1/269 23/18639 0.0434782608695652 3.01260707935995 0.284344174914778 0.516573901995472 GO:0140103 catalytic activity, acting on a glycoprotein 1/269 23/18639 0.0434782608695652 3.01260707935995 0.284344174914778 0.516573901995472 GO:0046943 carboxylic acid transmembrane transporter activity 4/269 188/18639 0.0212765957446809 1.47425452819742 0.288019702050574 0.516573901995472 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 3/269 130/18639 0.0230769230769231 1.59899914212182 0.289470276679297 0.516573901995472 GO:0005342 organic acid transmembrane transporter activity 4/269 189/18639 0.0211640211640212 1.46645423968844 0.291245116910659 0.516573901995472 GO:0015149 hexose transmembrane transporter activity 1/269 24/18639 0.0416666666666667 2.88708178438662 0.294685355455599 0.516573901995472 GO:0015295 solute:proton symporter activity 1/269 24/18639 0.0416666666666667 2.88708178438662 0.294685355455599 0.516573901995472 GO:0019957 C-C chemokine binding 1/269 24/18639 0.0416666666666667 2.88708178438662 0.294685355455599 0.516573901995472 GO:0042625 ATPase-coupled ion transmembrane transporter activity 1/269 24/18639 0.0416666666666667 2.88708178438662 0.294685355455599 0.516573901995472 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 1/269 24/18639 0.0416666666666667 2.88708178438662 0.294685355455599 0.516573901995472 GO:0046961 proton-transporting ATPase activity, rotational mechanism 1/269 24/18639 0.0416666666666667 2.88708178438662 0.294685355455599 0.516573901995472 GO:0050431 transforming growth factor beta binding 1/269 24/18639 0.0416666666666667 2.88708178438662 0.294685355455599 0.516573901995472 GO:0055056 D-glucose transmembrane transporter activity 1/269 24/18639 0.0416666666666667 2.88708178438662 0.294685355455599 0.516573901995472 GO:0060229 lipase activator activity 1/269 24/18639 0.0416666666666667 2.88708178438662 0.294685355455599 0.516573901995472 GO:0003725 double-stranded RNA binding 2/269 75/18639 0.0266666666666667 1.84773234200743 0.294789042462533 0.516573901995472 GO:0051536 iron-sulfur cluster binding 2/269 76/18639 0.0263157894736842 1.82342007434944 0.300128072375333 0.519708440160161 GO:0015271 outward rectifier potassium channel activity 1/269 25/18639 0.04 2.77159851301115 0.304877654106281 0.519708440160161 GO:0016895 DNA exonuclease activity, producing 5'-phosphomonoesters 1/269 25/18639 0.04 2.77159851301115 0.304877654106281 0.519708440160161 GO:0017025 TBP-class protein binding 1/269 25/18639 0.04 2.77159851301115 0.304877654106281 0.519708440160161 GO:0019211 phosphatase activator activity 1/269 25/18639 0.04 2.77159851301115 0.304877654106281 0.519708440160161 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 1/269 25/18639 0.04 2.77159851301115 0.304877654106281 0.519708440160161 GO:0120020 cholesterol transfer activity 1/269 25/18639 0.04 2.77159851301115 0.304877654106281 0.519708440160161 GO:0051540 metal cluster binding 2/269 77/18639 0.025974025974026 1.79973929416309 0.305460471763096 0.519708440160161 GO:0140789 histone phosphatase activity 3/269 136/18639 0.0220588235294118 1.52845506232233 0.313115471482777 0.519708440160161 GO:0001637 G protein-coupled chemoattractant receptor activity 1/269 26/18639 0.0384615384615385 2.66499857020303 0.314923206434927 0.519708440160161 GO:0004435 phosphatidylinositol phospholipase C activity 1/269 26/18639 0.0384615384615385 2.66499857020303 0.314923206434927 0.519708440160161 GO:0004529 DNA exonuclease activity 1/269 26/18639 0.0384615384615385 2.66499857020303 0.314923206434927 0.519708440160161 GO:0004950 chemokine receptor activity 1/269 26/18639 0.0384615384615385 2.66499857020303 0.314923206434927 0.519708440160161 GO:0005112 Notch binding 1/269 26/18639 0.0384615384615385 2.66499857020303 0.314923206434927 0.519708440160161 GO:0015145 monosaccharide transmembrane transporter activity 1/269 26/18639 0.0384615384615385 2.66499857020303 0.314923206434927 0.519708440160161 GO:0030247 polysaccharide binding 1/269 26/18639 0.0384615384615385 2.66499857020303 0.314923206434927 0.519708440160161 GO:0030507 spectrin binding 1/269 26/18639 0.0384615384615385 2.66499857020303 0.314923206434927 0.519708440160161 GO:0034237 protein kinase A regulatory subunit binding 1/269 26/18639 0.0384615384615385 2.66499857020303 0.314923206434927 0.519708440160161 GO:0070006 metalloaminopeptidase activity 1/269 26/18639 0.0384615384615385 2.66499857020303 0.314923206434927 0.519708440160161 GO:0015370 solute:sodium symporter activity 2/269 79/18639 0.0253164556962025 1.75417627405769 0.316101734623354 0.519708440160161 GO:0016835 carbon-oxygen lyase activity 2/269 79/18639 0.0253164556962025 1.75417627405769 0.316101734623354 0.519708440160161 GO:0048306 calcium-dependent protein binding 2/269 80/18639 0.025 1.73224907063197 0.32140884452049 0.526884293510129 GO:0051119 sugar transmembrane transporter activity 1/269 28/18639 0.0357142857142857 2.47464152947424 0.334582462235116 0.544889487572921 GO:0020037 heme binding 3/269 142/18639 0.0211267605633803 1.46387245405519 0.33680885743357 0.544889487572921 GO:0001540 amyloid-beta binding 2/269 83/18639 0.0240963855421687 1.66963765844045 0.337266122898445 0.544889487572921 GO:0008135 translation factor activity, RNA binding 2/269 83/18639 0.0240963855421687 1.66963765844045 0.337266122898445 0.544889487572921 GO:0030165 PDZ domain binding 2/269 83/18639 0.0240963855421687 1.66963765844045 0.337266122898445 0.544889487572921 GO:0004860 protein kinase inhibitor activity 2/269 84/18639 0.0238095238095238 1.6497610196495 0.342527912956922 0.545065042099432 GO:0051117 ATPase binding 2/269 84/18639 0.0238095238095238 1.6497610196495 0.342527912956922 0.545065042099432 GO:0180051 translation factor activity 2/269 84/18639 0.0238095238095238 1.6497610196495 0.342527912956922 0.545065042099432 GO:0003785 actin monomer binding 1/269 29/18639 0.0344827586206897 2.38930906294065 0.344200285976922 0.545065042099432 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 1/269 29/18639 0.0344827586206897 2.38930906294065 0.344200285976922 0.545065042099432 GO:0043236 laminin binding 1/269 29/18639 0.0344827586206897 2.38930906294065 0.344200285976922 0.545065042099432 GO:0097472 cyclin-dependent protein kinase activity 1/269 29/18639 0.0344827586206897 2.38930906294065 0.344200285976922 0.545065042099432 GO:0015293 symporter activity 3/269 146/18639 0.0205479452054795 1.42376635942354 0.352586325794045 0.552253908034731 GO:0001965 G-protein alpha-subunit binding 1/269 30/18639 0.0333333333333333 2.30966542750929 0.353679604787895 0.552253908034731 GO:0008106 alcohol dehydrogenase (NADP+) activity 1/269 30/18639 0.0333333333333333 2.30966542750929 0.353679604787895 0.552253908034731 GO:0031210 phosphatidylcholine binding 1/269 30/18639 0.0333333333333333 2.30966542750929 0.353679604787895 0.552253908034731 GO:0070566 adenylyltransferase activity 1/269 30/18639 0.0333333333333333 2.30966542750929 0.353679604787895 0.552253908034731 GO:0008081 phosphoric diester hydrolase activity 2/269 87/18639 0.0229885057471264 1.5928727086271 0.358231060034983 0.557802681224388 GO:0005310 dicarboxylic acid transmembrane transporter activity 1/269 31/18639 0.032258064516129 2.23516009113803 0.363022405922403 0.561217060964158 GO:0005452 solute:inorganic anion antiporter activity 1/269 31/18639 0.032258064516129 2.23516009113803 0.363022405922403 0.561217060964158 GO:0004197 cysteine-type endopeptidase activity 2/269 88/18639 0.0227272727272727 1.5747718823927 0.363435735364982 0.561217060964158 GO:0015106 bicarbonate transmembrane transporter activity 1/269 32/18639 0.03125 2.16531133828996 0.372230648227158 0.56626642805465 GO:0030515 snoRNA binding 1/269 32/18639 0.03125 2.16531133828996 0.372230648227158 0.56626642805465 GO:0071813 lipoprotein particle binding 1/269 32/18639 0.03125 2.16531133828996 0.372230648227158 0.56626642805465 GO:0071814 protein-lipid complex binding 1/269 32/18639 0.03125 2.16531133828996 0.372230648227158 0.56626642805465 GO:0120015 sterol transfer activity 1/269 32/18639 0.03125 2.16531133828996 0.372230648227158 0.56626642805465 GO:0001217 DNA-binding transcription repressor activity 5/269 278/18639 0.0179856115107914 1.24622235297264 0.373538736439963 0.56626642805465 GO:0019210 kinase inhibitor activity 2/269 90/18639 0.0222222222222222 1.53977695167286 0.37379662245468 0.56626642805465 GO:0046906 tetrapyrrole binding 3/269 152/18639 0.0197368421052632 1.36756505576208 0.376163269781128 0.568311534615272 GO:0072341 modified amino acid binding 2/269 91/18639 0.021978021978022 1.5228563258303 0.378951608997881 0.569920322895988 GO:0019239 deaminase activity 1/269 33/18639 0.0303030303030303 2.09969584319027 0.381306262545795 0.569920322895988 GO:0030296 protein tyrosine kinase activator activity 1/269 33/18639 0.0303030303030303 2.09969584319027 0.381306262545795 0.569920322895988 GO:0140311 protein sequestering activity 1/269 33/18639 0.0303030303030303 2.09969584319027 0.381306262545795 0.569920322895988 GO:0008376 acetylgalactosaminyltransferase activity 1/269 34/18639 0.0294117647058824 2.03794008309644 0.390251152117718 0.574079984299485 GO:0015035 protein-disulfide reductase activity 1/269 34/18639 0.0294117647058824 2.03794008309644 0.390251152117718 0.574079984299485 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 1/269 34/18639 0.0294117647058824 2.03794008309644 0.390251152117718 0.574079984299485 GO:0030332 cyclin binding 1/269 34/18639 0.0294117647058824 2.03794008309644 0.390251152117718 0.574079984299485 GO:0051427 hormone receptor binding 1/269 34/18639 0.0294117647058824 2.03794008309644 0.390251152117718 0.574079984299485 GO:0090482 vitamin transmembrane transporter activity 1/269 34/18639 0.0294117647058824 2.03794008309644 0.390251152117718 0.574079984299485 GO:0042562 hormone binding 2/269 94/18639 0.0212765957446809 1.47425452819742 0.394307823836057 0.578525127360515 GO:0000175 3'-5'-RNA exonuclease activity 1/269 35/18639 0.0285714285714286 1.97971322357939 0.399067192971269 0.582450550576866 GO:0005343 organic acid:sodium symporter activity 1/269 35/18639 0.0285714285714286 1.97971322357939 0.399067192971269 0.582450550576866 GO:0004033 aldo-keto reductase (NADPH) activity 1/269 36/18639 0.0277777777777778 1.92472118959108 0.407756234311343 0.592040870078028 GO:0004190 aspartic-type endopeptidase activity 1/269 36/18639 0.0277777777777778 1.92472118959108 0.407756234311343 0.592040870078028 GO:0042626 ATPase-coupled transmembrane transporter activity 2/269 98/18639 0.0204081632653061 1.41408087398528 0.41450935686993 0.599801379602901 GO:0030280 structural constituent of skin epidermis 1/269 37/18639 0.027027027027027 1.87270169798051 0.416320098901477 0.599801379602901 GO:0070001 aspartic-type peptidase activity 1/269 37/18639 0.027027027027027 1.87270169798051 0.416320098901477 0.599801379602901 GO:0043130 ubiquitin binding 2/269 100/18639 0.02 1.38579925650558 0.424484291583348 0.602797399446048 GO:0005109 frizzled binding 1/269 38/18639 0.0263157894736842 1.82342007434944 0.424760583440532 0.602797399446048 GO:0005501 retinoid binding 1/269 38/18639 0.0263157894736842 1.82342007434944 0.424760583440532 0.602797399446048 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 1/269 38/18639 0.0263157894736842 1.82342007434944 0.424760583440532 0.602797399446048 GO:0019840 isoprenoid binding 1/269 38/18639 0.0263157894736842 1.82342007434944 0.424760583440532 0.602797399446048 GO:0000287 magnesium ion binding 4/269 230/18639 0.0173913043478261 1.20504283174398 0.424869723402045 0.602797399446048 GO:0015399 primary active transmembrane transporter activity 3/269 166/18639 0.0180722891566265 1.25222824383034 0.430374651954099 0.609061849221117 GO:0004177 aminopeptidase activity 1/269 40/18639 0.025 1.73224907063197 0.441278471060196 0.615148791328303 GO:0004532 RNA exonuclease activity 1/269 40/18639 0.025 1.73224907063197 0.441278471060196 0.615148791328303 GO:0015144 carbohydrate transmembrane transporter activity 1/269 40/18639 0.025 1.73224907063197 0.441278471060196 0.615148791328303 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 1/269 40/18639 0.025 1.73224907063197 0.441278471060196 0.615148791328303 GO:0050997 quaternary ammonium group binding 1/269 40/18639 0.025 1.73224907063197 0.441278471060196 0.615148791328303 GO:0071855 neuropeptide receptor binding 1/269 40/18639 0.025 1.73224907063197 0.441278471060196 0.615148791328303 GO:0001530 lipopolysaccharide binding 1/269 41/18639 0.024390243902439 1.68999909329948 0.449359340530856 0.618699190533863 GO:0001727 lipid kinase activity 1/269 41/18639 0.024390243902439 1.68999909329948 0.449359340530856 0.618699190533863 GO:0008137 NADH dehydrogenase (ubiquinone) activity 1/269 41/18639 0.024390243902439 1.68999909329948 0.449359340530856 0.618699190533863 GO:0017080 sodium channel regulator activity 1/269 41/18639 0.024390243902439 1.68999909329948 0.449359340530856 0.618699190533863 GO:0042169 SH2 domain binding 1/269 41/18639 0.024390243902439 1.68999909329948 0.449359340530856 0.618699190533863 GO:0008307 structural constituent of muscle 1/269 42/18639 0.0238095238095238 1.6497610196495 0.457323763447148 0.625046415078131 GO:0019894 kinesin binding 1/269 42/18639 0.0238095238095238 1.6497610196495 0.457323763447148 0.625046415078131 GO:0031492 nucleosomal DNA binding 1/269 42/18639 0.0238095238095238 1.6497610196495 0.457323763447148 0.625046415078131 GO:0019888 protein phosphatase regulator activity 2/269 107/18639 0.0186915887850467 1.29513949206129 0.458679733665001 0.625370661265209 GO:0003735 structural constituent of ribosome 3/269 175/18639 0.0171428571428571 1.18782793414764 0.464335546978534 0.628096466455262 GO:0004721 phosphoprotein phosphatase activity 3/269 175/18639 0.0171428571428571 1.18782793414764 0.464335546978534 0.628096466455262 GO:0005245 voltage-gated calcium channel activity 1/269 43/18639 0.0232558139534884 1.61139448430881 0.46517341165023 0.628096466455262 GO:0008375 acetylglucosaminyltransferase activity 1/269 43/18639 0.0232558139534884 1.61139448430881 0.46517341165023 0.628096466455262 GO:0004620 phospholipase activity 2/269 109/18639 0.018348623853211 1.27137546468401 0.468233418082509 0.630704772790656 GO:0043021 ribonucleoprotein complex binding 3/269 177/18639 0.0169491525423729 1.174406149581 0.471764598824646 0.630922798530902 GO:0001046 core promoter sequence-specific DNA binding 1/269 44/18639 0.0227272727272727 1.5747718823927 0.472909933066991 0.630922798530902 GO:0001223 transcription coactivator binding 1/269 44/18639 0.0227272727272727 1.5747718823927 0.472909933066991 0.630922798530902 GO:0003954 NADH dehydrogenase activity 1/269 44/18639 0.0227272727272727 1.5747718823927 0.472909933066991 0.630922798530902 GO:0033218 amide binding 4/269 247/18639 0.0161943319838057 1.12210466113812 0.478935244434291 0.63744000390183 GO:0004715 non-membrane spanning protein tyrosine kinase activity 1/269 45/18639 0.0222222222222222 1.53977695167286 0.480534952050856 0.638049971963013 GO:0005200 structural constituent of cytoskeleton 2/269 112/18639 0.0178571428571429 1.23732076473712 0.482374523284446 0.638974783213283 GO:0030291 protein serine/threonine kinase inhibitor activity 1/269 46/18639 0.0217391304347826 1.50630353967997 0.488050069717755 0.644964512936703 GO:0022804 active transmembrane transporter activity 7/269 457/18639 0.0153172866520788 1.06133422270668 0.490263827957672 0.646361980727214 GO:0001784 phosphotyrosine residue binding 1/269 47/18639 0.0212765957446809 1.47425452819742 0.495456864277317 0.650141753828686 GO:0140359 ABC-type transporter activity 1/269 47/18639 0.0212765957446809 1.47425452819742 0.495456864277317 0.650141753828686 GO:0009055 electron transfer activity 2/269 116/18639 0.0172413793103448 1.19465453147032 0.500865301545358 0.654341853745969 GO:0015078 proton transmembrane transporter activity 3/269 185/18639 0.0162162162162162 1.12362101878831 0.5009987717411 0.654341853745969 GO:0022853 active monoatomic ion transmembrane transporter activity 2/269 118/18639 0.0169491525423729 1.174406149581 0.50995080485568 0.664481351781644 GO:0032182 ubiquitin-like protein binding 2/269 120/18639 0.0166666666666667 1.15483271375465 0.518927756261713 0.674606083140226 GO:0004540 RNA nuclease activity 2/269 121/18639 0.0165289256198347 1.14528864174015 0.523375125581276 0.676521154656705 GO:0005048 signal sequence binding 1/269 51/18639 0.0196078431372549 1.35862672206429 0.52403159206861 0.676521154656705 GO:0030544 Hsp70 protein binding 1/269 51/18639 0.0196078431372549 1.35862672206429 0.52403159206861 0.676521154656705 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 2/269 122/18639 0.0163934426229508 1.1359010299226 0.527794897979129 0.67980955753533 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 1/269 52/18639 0.0192307692307692 1.33249928510152 0.530919665112162 0.68226228229356 GO:0005544 calcium-dependent phospholipid binding 1/269 53/18639 0.0188679245283019 1.3073577891562 0.537708421236595 0.68313410788922 GO:0016251 RNA polymerase II general transcription initiation factor activity 1/269 53/18639 0.0188679245283019 1.3073577891562 0.537708421236595 0.68313410788922 GO:0017046 peptide hormone binding 1/269 53/18639 0.0188679245283019 1.3073577891562 0.537708421236595 0.68313410788922 GO:0051018 protein kinase A binding 1/269 53/18639 0.0188679245283019 1.3073577891562 0.537708421236595 0.68313410788922 GO:0140296 general transcription initiation factor binding 1/269 53/18639 0.0188679245283019 1.3073577891562 0.537708421236595 0.68313410788922 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 4/269 268/18639 0.0149253731343284 1.03417854963103 0.542814369886613 0.685403607075534 GO:0017069 snRNA binding 1/269 54/18639 0.0185185185185185 1.28314745972739 0.544399287194163 0.685403607075534 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 1/269 54/18639 0.0185185185185185 1.28314745972739 0.544399287194163 0.685403607075534 GO:0050661 NADP binding 1/269 54/18639 0.0185185185185185 1.28314745972739 0.544399287194163 0.685403607075534 GO:0008514 organic anion transmembrane transporter activity 4/269 269/18639 0.0148698884758364 1.03033401970675 0.545757900612844 0.685570036949618 GO:0016829 lyase activity 3/269 200/18639 0.015 1.03934944237918 0.55348739054582 0.692468746790815 GO:0031490 chromatin DNA binding 2/269 128/18639 0.015625 1.08265566914498 0.553727244750437 0.692468746790815 GO:0016791 phosphatase activity 4/269 273/18639 0.0146520146520147 1.01523755055354 0.557433675023374 0.695547822183183 GO:0016298 lipase activity 2/269 130/18639 0.0153846153846154 1.06599942808121 0.562145658177377 0.699301916605247 GO:0005262 calcium channel activity 2/269 131/18639 0.0152671755725191 1.05786202786685 0.566312199666548 0.699301916605247 GO:0031072 heat shock protein binding 2/269 131/18639 0.0152671755725191 1.05786202786685 0.566312199666548 0.699301916605247 GO:0008408 3'-5' exonuclease activity 1/269 58/18639 0.0172413793103448 1.19465453147032 0.570211675767356 0.699301916605247 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 1/269 58/18639 0.0172413793103448 1.19465453147032 0.570211675767356 0.699301916605247 GO:0061980 regulatory RNA binding 1/269 58/18639 0.0172413793103448 1.19465453147032 0.570211675767356 0.699301916605247 GO:0005179 hormone activity 2/269 132/18639 0.0151515151515152 1.04984792159513 0.570450221774585 0.699301916605247 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 2/269 132/18639 0.0151515151515152 1.04984792159513 0.570450221774585 0.699301916605247 GO:0001786 phosphatidylserine binding 1/269 59/18639 0.0169491525423729 1.174406149581 0.576433787559971 0.700492363578312 GO:0015459 potassium channel regulator activity 1/269 59/18639 0.0169491525423729 1.174406149581 0.576433787559971 0.700492363578312 GO:0031593 polyubiquitin modification-dependent protein binding 1/269 59/18639 0.0169491525423729 1.174406149581 0.576433787559971 0.700492363578312 GO:0045309 protein phosphorylated amino acid binding 1/269 59/18639 0.0169491525423729 1.174406149581 0.576433787559971 0.700492363578312 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 1/269 60/18639 0.0166666666666667 1.15483271375465 0.582566150915534 0.706408846771765 GO:0016922 nuclear receptor binding 2/269 137/18639 0.0145985401459854 1.01153230401867 0.590711129124161 0.714734894329883 GO:0015291 secondary active transmembrane transporter activity 4/269 287/18639 0.0139372822299652 0.965713767599705 0.5969936974361 0.720776407919612 GO:0005507 copper ion binding 1/269 63/18639 0.0158730158730159 1.09984067976633 0.600437556093311 0.721816330873464 GO:1901682 sulfur compound transmembrane transporter activity 1/269 63/18639 0.0158730158730159 1.09984067976633 0.600437556093311 0.721816330873464 GO:0004536 DNA nuclease activity 1/269 64/18639 0.015625 1.08265566914498 0.606223640148592 0.727208186358504 GO:0120013 lipid transfer activity 1/269 65/18639 0.0153846153846154 1.06599942808121 0.611926242614273 0.732477022743851 GO:0022843 voltage-gated monoatomic cation channel activity 2/269 143/18639 0.013986013986014 0.969090389164739 0.614077552175384 0.733481520653931 GO:0008235 metalloexopeptidase activity 1/269 66/18639 0.0151515151515152 1.04984792159513 0.617546563532587 0.735467097470298 GO:0046982 protein heterodimerization activity 5/269 369/18639 0.013550135501355 0.93888838516638 0.618371262631556 0.735467097470298 GO:0008194 UDP-glycosyltransferase activity 2/269 145/18639 0.0137931034482759 0.95572362517626 0.621636985733662 0.736374110442363 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 1/269 67/18639 0.0149253731343284 1.03417854963103 0.623085785758922 0.736374110442363 GO:0042054 histone methyltransferase activity 1/269 67/18639 0.0149253731343284 1.03417854963103 0.623085785758922 0.736374110442363 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 1/269 68/18639 0.0147058823529412 1.01897004154822 0.628545075207062 0.738774943135816 GO:0140223 general transcription initiation factor activity 1/269 68/18639 0.0147058823529412 1.01897004154822 0.628545075207062 0.738774943135816 GO:0015085 calcium ion transmembrane transporter activity 2/269 147/18639 0.0136054421768707 0.942720582656854 0.629082062491321 0.738774943135816 GO:0002039 p53 binding 1/269 69/18639 0.0144927536231884 1.00420235978665 0.633925581090929 0.742902305722913 GO:0016782 transferase activity, transferring sulphur-containing groups 1/269 70/18639 0.0142857142857143 0.989856611789697 0.639228436162903 0.747549572834859 GO:0003774 cytoskeletal motor activity 2/269 153/18639 0.0130718954248366 0.90575114804286 0.65073473621026 0.759416946850805 GO:0005506 iron ion binding 2/269 154/18639 0.012987012987013 0.899869647081543 0.654244576286117 0.76192232946654 GO:0031491 nucleosome binding 1/269 74/18639 0.0135135135135135 0.936350848990254 0.659685440287929 0.766661457631918 GO:0051020 GTPase binding 4/269 315/18639 0.0126984126984127 0.879872543813064 0.669473608049299 0.776422711409872 GO:0099106 ion channel regulator activity 2/269 160/18639 0.0125 0.866124535315985 0.674716570764765 0.780883153328165 GO:0015081 sodium ion transmembrane transporter activity 2/269 164/18639 0.0121951219512195 0.844999546649742 0.687811898297188 0.793231474847234 GO:0000049 tRNA binding 1/269 80/18639 0.0125 0.866124535315985 0.688224088194828 0.793231474847234 GO:0030971 receptor tyrosine kinase binding 1/269 81/18639 0.0123456790123457 0.855431639818257 0.69274306660291 0.796797066318984 GO:0042393 histone binding 3/269 247/18639 0.0121457489878543 0.841578495853589 0.694873528692151 0.797606370716453 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 2/269 167/18639 0.0119760479041916 0.829819914075195 0.697347723836568 0.79875086914764 GO:0140104 molecular carrier activity 3/269 249/18639 0.0120481927710843 0.834818829220227 0.700068518812343 0.79875086914764 GO:0016247 channel regulator activity 2/269 168/18639 0.0119047619047619 0.824880509824748 0.70047249644531 0.79875086914764 GO:0005254 chloride channel activity 1/269 83/18639 0.0120481927710843 0.834818829220227 0.701586183813043 0.79875086914764 GO:0004527 exonuclease activity 1/269 84/18639 0.0119047619047619 0.824880509824748 0.70591218707637 0.801243131462423 GO:0141108 transporter regulator activity 2/269 170/18639 0.0117647058823529 0.815176033238574 0.706641974617128 0.801243131462423 GO:0050660 flavin adenine dinucleotide binding 1/269 86/18639 0.0116279069767442 0.805697242154405 0.714377644273491 0.808232484075199 GO:0005244 voltage-gated monoatomic ion channel activity 2/269 173/18639 0.0115606936416185 0.801040032662183 0.715697816846553 0.808232484075199 GO:0022832 voltage-gated channel activity 2/269 175/18639 0.0114285714285714 0.791885289431758 0.721604236987536 0.81274359599475 GO:0016651 oxidoreductase activity, acting on NAD(P)H 1/269 88/18639 0.0113636363636364 0.78738594119635 0.722600299122345 0.81274359599475 GO:0016853 isomerase activity 2/269 180/18639 0.0111111111111111 0.769888475836431 0.735919990485629 0.826062800565194 GO:0052689 carboxylic ester hydrolase activity 1/269 92/18639 0.0108695652173913 0.753151769839987 0.738344759022498 0.827123687963078 GO:0051219 phosphoprotein binding 1/269 93/18639 0.010752688172043 0.745053363712675 0.742139726393121 0.829712214107509 GO:0004867 serine-type endopeptidase inhibitor activity 1/269 95/18639 0.0105263157894737 0.729368029739777 0.749565932521171 0.834676008524571 GO:0008276 protein methyltransferase activity 1/269 95/18639 0.0105263157894737 0.729368029739777 0.749565932521171 0.834676008524571 GO:0016407 acetyltransferase activity 1/269 96/18639 0.0104166666666667 0.721770446096654 0.753198739043594 0.837053867048447 GO:0008234 cysteine-type peptidase activity 2/269 187/18639 0.0106951871657754 0.741069121125977 0.754907927724281 0.837288753170383 GO:0030594 neurotransmitter receptor activity 1/269 97/18639 0.0103092783505155 0.714329513662668 0.756779041001059 0.837701948355627 GO:0005249 voltage-gated potassium channel activity 1/269 98/18639 0.0102040816326531 0.707040436992641 0.760307594445709 0.838287860542705 GO:0008170 N-methyltransferase activity 1/269 98/18639 0.0102040816326531 0.707040436992641 0.760307594445709 0.838287860542705 GO:0008017 microtubule binding 3/269 276/18639 0.0108695652173913 0.753151769839987 0.76373645132567 0.840410780100491 GO:0005253 monoatomic anion channel activity 1/269 103/18639 0.00970873786407767 0.672718085682319 0.777199845148745 0.852603493838109 GO:0005216 monoatomic ion channel activity 5/269 448/18639 0.0111607142857143 0.773325477960701 0.777867230514196 0.852603493838109 GO:0046873 metal ion transmembrane transporter activity 5/269 450/18639 0.0111111111111111 0.769888475836431 0.781137621193695 0.85451258365416 GO:0008013 beta-catenin binding 1/269 106/18639 0.00943396226415094 0.653678894578102 0.786760292983899 0.858982429253905 GO:0004843 cysteine-type deubiquitinase activity 1/269 108/18639 0.00925925925925926 0.641573729863693 0.792905732519744 0.86400449216089 GO:0008168 methyltransferase activity 2/269 204/18639 0.00980392156862745 0.679313361032145 0.796185947822214 0.86589094325412 GO:0004518 nuclease activity 2/269 209/18639 0.00956937799043062 0.663061845217979 0.807102718528203 0.876059067295661 GO:0015631 tubulin binding 4/269 385/18639 0.0103896103896104 0.719895717665234 0.809583166764536 0.87704843066158 GO:0017124 SH3 domain binding 1/269 115/18639 0.00869565217391304 0.60252141587199 0.813057862994121 0.877411863733037 GO:0101005 deubiquitinase activity 1/269 115/18639 0.00869565217391304 0.60252141587199 0.813057862994121 0.877411863733037 GO:0016741 transferase activity, transferring one-carbon groups 2/269 215/18639 0.00930232558139535 0.644557793723524 0.819515722040906 0.882676856687604 GO:0015108 chloride transmembrane transporter activity 1/269 121/18639 0.00826446280991736 0.572644320870073 0.828768204922504 0.890925820291692 GO:0008528 G protein-coupled peptide receptor activity 1/269 122/18639 0.00819672131147541 0.567950514961302 0.831255587624516 0.891884594015555 GO:0005267 potassium channel activity 1/269 124/18639 0.00806451612903226 0.558790022784507 0.836122871088772 0.895388285323034 GO:0022836 gated channel activity 3/269 318/18639 0.00943396226415094 0.653678894578102 0.84060384009154 0.898465672296693 GO:0019783 ubiquitin-like protein peptidase activity 1/269 127/18639 0.0078740157480315 0.545590258466762 0.843162767058758 0.899480890812683 GO:0001653 peptide receptor activity 1/269 128/18639 0.0078125 0.541327834572491 0.845441786919454 0.899621552474843 GO:0016755 aminoacyltransferase activity 5/269 496/18639 0.0100806451612903 0.698487528480633 0.846513303402089 0.899621552474843 GO:0016798 hydrolase activity, acting on glycosyl bonds 1/269 130/18639 0.00769230769230769 0.532999714040606 0.849901316472412 0.901508227529561 GO:0016887 ATP hydrolysis activity 4/269 417/18639 0.00959232613908873 0.664651921585408 0.855336933164869 0.905555578862049 GO:0015297 antiporter activity 1/269 135/18639 0.00740740740740741 0.513258983890954 0.860497235173363 0.909296700306068 GO:0140101 catalytic activity, acting on a tRNA 1/269 139/18639 0.00719424460431655 0.498488941189056 0.868434709516284 0.915952835131326 GO:0005261 monoatomic cation channel activity 3/269 341/18639 0.00879765395894428 0.609589115764916 0.872787862456145 0.918810574600725 GO:0008509 monoatomic anion transmembrane transporter activity 1/269 149/18639 0.00671140939597315 0.465033307552207 0.886364673777526 0.928176417567327 GO:0061630 ubiquitin protein ligase activity 3/269 353/18639 0.0084985835694051 0.588866539591605 0.8871938403899 0.928176417567327 GO:0019842 vitamin binding 1/269 150/18639 0.00666666666666667 0.461933085501859 0.888017886473786 0.928176417567327 GO:0141003 histone H2AX kinase activity 3/269 354/18639 0.00847457627118644 0.587203074790498 0.888326267260321 0.928176417567327 GO:0004842 ubiquitin-protein transferase activity 4/269 449/18639 0.0089086859688196 0.617282519601593 0.891431064820171 0.928192992702076 GO:0140996 histone H3 kinase activity 3/269 357/18639 0.00840336134453781 0.58226859517041 0.891663035923104 0.928192992702076 GO:0035173 histone kinase activity 3/269 360/18639 0.00833333333333333 0.577416356877323 0.894910541460113 0.929841993821939 GO:0015079 potassium ion transmembrane transporter activity 1/269 160/18639 0.00625 0.433062267657993 0.903287513186677 0.936804675085997 GO:0005096 GTPase activator activity 2/269 271/18639 0.00738007380073801 0.511365039300951 0.904981786712614 0.936823738467317 GO:0061659 ubiquitin-like protein ligase activity 3/269 372/18639 0.00806451612903226 0.558790022784507 0.907046037819318 0.937225018744914 GO:0015103 inorganic anion transmembrane transporter activity 1/269 165/18639 0.00606060606060606 0.419939168638053 0.910125501509757 0.938671873328328 GO:0031267 small GTPase binding 2/269 283/18639 0.00706713780918728 0.489681716079709 0.917535386740375 0.942346341161223 GO:0019787 ubiquitin-like protein transferase activity 4/269 479/18639 0.00835073068893528 0.578621819000241 0.917872975382448 0.942346341161223 GO:0140030 modification-dependent protein binding 1/269 173/18639 0.00578034682080925 0.400520016331091 0.920078301861027 0.942346341161223 GO:0140098 catalytic activity, acting on RNA 3/269 387/18639 0.00775193798449612 0.537131494769603 0.920431309971427 0.942346341161223 GO:0015276 ligand-gated monoatomic ion channel activity 1/269 186/18639 0.00537634408602151 0.372526681856338 0.933962883325246 0.954452014220864 GO:0022834 ligand-gated channel activity 1/269 188/18639 0.00531914893617021 0.368563632049355 0.935874223574926 0.954660020033547 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 1/269 229/18639 0.00436681222707424 0.302576256878947 0.964905570403779 0.981216111950667 GO:0005085 guanyl-nucleotide exchange factor activity 1/269 230/18639 0.00434782608695652 0.301260707935995 0.965418357017651 0.981216111950667 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 3/269 484/18639 0.00619834710743802 0.429483240652555 0.972269243692979 0.983090667327598 GO:0030695 GTPase regulator activity 3/269 489/18639 0.00613496932515337 0.425091796474103 0.973788195409532 0.983090667327598 GO:0060589 nucleoside-triphosphatase regulator activity 3/269 490/18639 0.00612244897959184 0.424224262195585 0.974082396754169 0.983090667327598 GO:0001216 DNA-binding transcription activator activity 3/269 491/18639 0.00610997963340122 0.423360261661581 0.974373474221362 0.983090667327598 GO:0005543 phospholipid binding 3/269 497/18639 0.00603621730382294 0.418249272587196 0.976056029278743 0.983090667327598 GO:0003730 mRNA 3'-UTR binding 1/269 262/18639 0.00381679389312977 0.264465506966713 0.978417655390073 0.983696887343616 GO:0140097 catalytic activity, acting on DNA 1/269 336/18639 0.00297619047619048 0.206220127456187 0.992768269236172 0.996332966791777 GO:0045182 translation regulator activity 1/269 356/18639 0.00280898876404494 0.1946347270373 0.994622620762735 0.996405098577722 GO:0004674 protein serine/threonine kinase activity 1/269 433/18639 0.0023094688221709 0.160023008834362 0.998286604272986 0.998286604272986