category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Human Diseases	Cardiovascular disease	hsa05416	Viral myocarditis	12/123	70/9376	13.0675958188153	HLA-C/HLA-A/HLA-DRB5/CCND1/HLA-DRB1/HLA-E/HLA-B/RAC2/HLA-DQB1/CAV1/ITGB2/ITGAL	11.6838282585705
Organismal Systems	Immune system	hsa04612	Antigen processing and presentation	11/123	82/9376	10.225659329764	HLA-C/B2M/HLA-A/HLA-DRB5/HLA-DRB1/HLA-E/HLA-B/CTSS/CTSL/HLA-DQB1/KLRC1	9.67386268651202
Organismal Systems	Immune system	hsa04610	Complement and coagulation cascades	11/123	88/9376	9.52845528455285	FGG/C1QA/CLU/CD59/FGB/CFH/C1QB/F2RL3/ITGB2/FGA/ITGAX	9.26717837247453
Human Diseases	Immune disease	hsa05332	Graft-versus-host disease	8/123	45/9376	13.5515808491418	HLA-C/HLA-A/HLA-DRB5/HLA-DRB1/HLA-E/HLA-B/HLA-DQB1/KLRC1	9.73055256070361
Human Diseases	Infectious disease: viral	hsa05166	Human T-cell leukemia virus 1 infection	15/123	224/9376	5.10452961672474	HLA-C/B2M/HLA-A/HLA-DRB5/CCND1/HLA-DRB1/HLA-E/HLA-B/HLA-DQB1/IL2RG/CD3G/ITGB2/ITGAL/SLC25A4/ETS1	7.16846732495078
Human Diseases	Infectious disease: viral	hsa05169	Epstein-Barr virus infection	14/123	205/9376	5.20579020424351	HLA-C/B2M/HLA-A/HLA-DRB5/CCND1/HLA-DRB1/ISG15/HLA-E/HLA-B/HLA-DQB1/CD247/CD3G/STAT1/ITGAL	7.01961190410456
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	15/123	238/9376	4.80426316868211	FGG/ISG15/C1QA/FGB/RPS19/RPS26/C1QB/RPLP2/RPL39/RPS21/RPS27A/STAT1/FGA/IFIH1/UBA52	6.8537832709403
Human Diseases	Immune disease	hsa05330	Allograft rejection	7/123	39/9376	13.6818845111528	HLA-C/HLA-A/HLA-DRB5/HLA-DRB1/HLA-E/HLA-B/HLA-DQB1	9.14975216861499
Environmental Information Processing	Signaling molecules and interaction	hsa04514	Cell adhesion molecule (CAM) interaction	12/123	160/9376	5.71707317073171	HLA-C/HLA-A/HLA-DRB5/HLA-DRB1/PTPRC/HLA-E/HLA-B/CD2/HLA-DQB1/ITGB2/ITGAL/ITGA4	6.93838323724032
Organismal Systems	Immune system	hsa04650	Natural killer cell mediated cytotoxicity	11/123	133/9376	6.3045418424109	HLA-C/HLA-A/HLA-E/HLA-B/RAC2/HCST/CD247/CD48/ITGB2/KLRC1/ITGAL	7.10336508530585
Human Diseases	Endocrine and metabolic disease	hsa04940	Type I diabetes mellitus	7/123	44/9376	12.1271249076127	HLA-C/HLA-A/HLA-DRB5/HLA-DRB1/HLA-E/HLA-B/HLA-DQB1	8.52940721639962
Human Diseases	Infectious disease: viral	hsa05168	Herpes simplex virus 1 infection	12/123	180/9376	5.08184281842818	HLA-C/CCL5/B2M/HLA-A/HLA-DRB5/HLA-DRB1/HLA-E/HLA-B/BST2/HLA-DQB1/STAT1/IFIH1	6.37514344591471
Human Diseases	Infectious disease: viral	hsa05170	Human immunodeficiency virus 1 infection	13/123	214/9376	4.63065116632475	HLA-C/B2M/HLA-A/HLA-E/HLA-B/GNG11/RAC2/SAMHD1/BST2/CD247/CD3G/CALM1/CCR5	6.19431347121612
Human Diseases	Infectious disease: bacterial	hsa05150	Staphylococcus aureus infection	9/123	99/9376	6.92978566149298	HLA-DRB5/FGG/HLA-DRB1/C1QA/CFH/C1QB/HLA-DQB1/ITGB2/ITGAL	6.83832484408449
Organismal Systems	Immune system	hsa04640	Hematopoietic cell lineage	9/123	100/9376	6.86048780487805	HLA-DRB5/CD9/HLA-DRB1/CD59/CD2/HLA-DQB1/CD3G/CD7/ITGA4	6.79282317273912
Human Diseases	Immune disease	hsa05320	Autoimmune thyroid disease	7/123	54/9376	9.88136103583258	HLA-C/HLA-A/HLA-DRB5/HLA-DRB1/HLA-E/HLA-B/HLA-DQB1	7.54603418583521
NA	NA	hsa04518	Integrin signaling	10/123	154/9376	4.94984690106641	FGG/CCND1/FGB/RAC2/SPP1/ITGB2/FGA/ITGAL/ITGAX/ITGA4	5.69803321753911
Cellular Processes	Transport and catabolism	hsa04145	Phagosome	10/123	155/9376	4.9179124049305	HLA-C/HLA-A/HLA-DRB5/HLA-DRB1/HLA-E/HLA-B/CTSS/CTSL/HLA-DQB1/ITGB2	5.67059294072479
Environmental Information Processing	Signaling molecules and interaction	hsa04061	Viral protein interaction with cytokine and cytokine receptor	8/123	100/9376	6.09821138211382	CCL5/CCL21/CCL18/XCL1/XCL2/IL2RG/CCR5/ACKR3	5.90927744736869
Human Diseases	Infectious disease: viral	hsa05167	Kaposi sarcoma-associated herpesvirus infection	11/123	196/9376	4.27808196449311	HLA-C/HLA-A/CCND1/HLA-E/HLA-B/GNG11/CALM1/RPS27A/CCR5/STAT1/UBA52	5.34716291622936
Human Diseases	Infectious disease: viral	hsa05163	Human cytomegalovirus infection	11/123	227/9376	3.69385050678701	HLA-C/CCL5/B2M/HLA-A/CCND1/HLA-E/HLA-B/GNG11/RAC2/CALM1/CCR5	4.73692511202513
Organismal Systems	Immune system	hsa04658	Th1 and Th2 cell differentiation	7/123	93/9376	5.73756447241892	HLA-DRB5/HLA-DRB1/HLA-DQB1/IL2RG/CD247/CD3G/STAT1	5.29357834610635
Cellular Processes	Cell growth and death	hsa04218	Cellular senescence	9/123	157/9376	4.36973745533634	HLA-C/HLA-A/CCND1/HLA-E/HLA-B/IGFBP3/CALM1/SLC25A4/ETS1	4.90908889828337
Human Diseases	Immune disease	hsa05323	Rheumatoid arthritis	7/123	95/9376	5.61677364142062	CCL5/HLA-DRB5/HLA-DRB1/CTSL/HLA-DQB1/ITGB2/ITGAL	5.21434678474388
Human Diseases	Infectious disease: parasitic	hsa05140	Leishmaniasis	6/123	78/9376	5.86366479049406	HLA-DRB5/HLA-DRB1/HLA-DQB1/ITGB2/STAT1/ITGA4	4.9729383865474
NA	NA	hsa04517	IgSF CAM signaling	12/123	299/9376	3.05930336895342	FGG/FGB/CD2/MYL12A/CD96/CD48/ITGB2/FGA/PMP22/ITGAL/ITGAX/ITGA4	4.17235900132855
Organismal Systems	Immune system	hsa04659	Th17 cell differentiation	7/123	109/9376	4.89535317371522	HLA-DRB5/HLA-DRB1/HLA-DQB1/IL2RG/CD247/CD3G/STAT1	4.71614793593189
Human Diseases	Infectious disease: bacterial	hsa05152	Tuberculosis	9/123	181/9376	3.79032475407627	HLA-DRB5/HLA-DRB1/CTSD/CTSS/HLA-DQB1/CALM1/ITGB2/STAT1/ITGAX	4.37033859353717
Organismal Systems	Immune system	hsa04062	Chemokine signaling pathway	9/123	193/9376	3.5546568937192	CCL5/CCL21/CCL18/GNG11/RAC2/XCL1/XCL2/CCR5/STAT1	4.13443201661273
Human Diseases	Immune disease	hsa05321	Inflammatory bowel disease	5/123	66/9376	5.77482138457748	HLA-DRB5/HLA-DRB1/HLA-DQB1/IL2RG/STAT1	4.48798266064599
Human Diseases	Infectious disease: viral	hsa05164	Influenza A	8/123	173/9376	3.52497767752244	CCL5/HLA-DRB5/HLA-DRB1/TPSAB1/HLA-DQB1/STAT1/IFIH1/SLC25A4	3.86467338602971
Metabolism	Global and overview maps	hsa01230	Biosynthesis of amino acids	5/123	75/9376	5.08184281842818	GAPDH/GLUL/ENO1/ENO2/TPI1	4.09184335373064
Organismal Systems	Immune system	hsa04672	Intestinal immune network for IgA production	4/123	50/9376	6.09821138211382	HLA-DRB5/HLA-DRB1/HLA-DQB1/ITGA4	4.16727391590717
Organismal Systems	Immune system	hsa04670	Leukocyte transendothelial migration	6/123	116/9376	3.94280908326325	THY1/RAC2/MYL12A/ITGB2/ITGAL/ITGA4	3.67690578570019
Cellular Processes	Transport and catabolism	hsa04144	Endocytosis	9/123	250/9376	2.74419512195122	HLA-C/HLA-A/HLA-E/HLA-B/WIPF1/IL2RG/ACAP1/CAV1/CCR5	3.22271390188491
Environmental Information Processing	Signaling molecules and interaction	hsa04060	Cytokine-cytokine receptor interaction	10/123	298/9376	2.55797457303432	CCL5/CCL21/CCL18/PRL/IL32/XCL1/XCL2/IL2RG/CCR5/ACKR3	3.15115902869777
Human Diseases	Immune disease	hsa05310	Asthma	3/123	32/9376	7.14634146341463	HLA-DRB5/HLA-DRB1/HLA-DQB1	4.01533857615972
Genetic Information Processing	Translation	hsa03010	Ribosome	8/123	222/9376	2.74694206401523	MRPS6/RPS19/RPS26/RPLP2/RPL39/RPS21/RPS27A/UBA52	3.03701158229173
Human Diseases	Infectious disease: parasitic	hsa05142	Chagas disease	5/123	103/9376	3.70037098429237	CCL5/C1QA/C1QB/CD247/CD3G	3.17708495592563
Metabolism	Carbohydrate metabolism	hsa00010	Glycolysis / Gluconeogenesis	4/123	67/9376	4.55090401650285	GAPDH/ENO1/ENO2/TPI1	3.36296023600535
Human Diseases	Infectious disease: viral	hsa05165	Human papillomavirus infection	10/123	333/9376	2.28911838667936	HLA-C/HLA-A/CCND1/ISG15/HLA-E/HLA-B/WNT5A/SPP1/STAT1/ITGA4	2.76156688930515
Organismal Systems	Immune system	hsa04613	Neutrophil extracellular trap formation	7/123	195/9376	2.73637690223056	FGG/FGB/RAC2/ITGB2/FGA/ITGAL/SLC25A4	2.82496599806878
Human Diseases	Infectious disease: parasitic	hsa05145	Toxoplasmosis	5/123	112/9376	3.40301974448316	HLA-DRB5/HLA-DRB1/HLA-DQB1/CCR5/STAT1	2.94960587886003
Cellular Processes	Cell growth and death	hsa04216	Ferroptosis	3/123	42/9376	5.44483159117305	FTL/FTH1/CP	3.32845715185341
Human Diseases	Infectious disease: bacterial	hsa05133	Pertussis	4/123	78/9376	3.90910986032937	C1QA/C1QB/CALM1/ITGB2	2.9744698120213
Metabolism	Energy metabolism	hsa00910	Nitrogen metabolism	2/123	17/9376	8.96795791487327	GLUL/CA12	3.79099910114156
Metabolism	Metabolism of cofactors and vitamins	hsa00860	Porphyrin metabolism	3/123	46/9376	4.97136797454931	FTL/FTH1/CP	3.1129714388642
Organismal Systems	Immune system	hsa04611	Platelet activation	5/123	126/9376	3.02490643954059	FGG/FGB/F2RL3/MYL12A/FGA	2.63825202731006
Human Diseases	Infectious disease: parasitic	hsa05144	Malaria	3/123	50/9376	4.57365853658537	HBB/ITGB2/ITGAL	2.9211056364039
Cellular Processes	Cell motility	hsa04810	Regulation of actin cytoskeleton	7/123	232/9376	2.29997196523689	RAC2/MYL12A/RGCC/ITGB2/ITGAL/ITGAX/ITGA4	2.31156858244402
Human Diseases	Infectious disease: viral	hsa05162	Measles	5/123	136/9376	2.8024868483979	CCND1/IL2RG/CD3G/STAT1/IFIH1	2.44119508020934
Cellular Processes	Cell motility	hsa04820	Cytoskeleton in muscle cells	7/123	233/9376	2.29010084092257	ANKRD1/TTN/SYNE2/ENO1/ENO2/DCN/ITGA4	2.29908046750428
Human Diseases	Cardiovascular disease	hsa05418	Fluid shear stress and atherosclerosis	5/123	142/9376	2.68407191114165	RAC2/CTSL/GSTT1/CAV1/CALM1	2.33134626471957
Human Diseases	Immune disease	hsa05322	Systemic lupus erythematosus	5/123	143/9376	2.6653021774973	HLA-DRB5/HLA-DRB1/C1QA/C1QB/HLA-DQB1	2.31359088025596
Human Diseases	Infectious disease: bacterial	hsa05132	Salmonella infection	7/123	248/9376	2.15158667715709	S100A10/GAPDH/PTPRC/MYL12A/ACTR1A/PKN1/PODXL	2.11900298929771
Cellular Processes	Transport and catabolism	hsa04137	Mitophagy - animal	4/123	105/9376	2.90391018195896	OPTN/CITED2/RPS27A/UBA52	2.26190691491045
Cellular Processes	Cellular community - eukaryotes	hsa04510	Focal adhesion	6/123	203/9376	2.25303376186471	CCND1/RAC2/MYL12A/CAV1/SPP1/ITGA4	2.08090382196255
Human Diseases	Cancer: overview	hsa05205	Proteoglycans in cancer	6/123	204/9376	2.24198947871832	CCND1/LUM/WNT5A/CTSL/CAV1/DCN	2.06774933740708
Human Diseases	Cancer: overview	hsa05203	Viral carcinogenesis	6/123	205/9376	2.23105294467579	HLA-C/HLA-A/CCND1/HLA-E/HLA-B/CCR5	2.054670700481
Metabolism	Global and overview maps	hsa01200	Carbon metabolism	4/123	116/9376	2.62853938884216	GAPDH/ENO1/ENO2/TPI1	2.03478572059945
Organismal Systems	Endocrine system	hsa04917	Prolactin signaling pathway	3/123	71/9376	3.22088629336998	CCND1/PRL/STAT1	2.16567968278157
Human Diseases	Neurodegenerative disease	hsa05020	Prion disease	7/123	275/9376	1.94033998521803	CCL5/C1QA/RAC2/C1QB/SOD1/CAV1/SLC25A4	1.82475098256851
Cellular Processes	Cell growth and death	hsa04217	Necroptosis	5/123	168/9376	2.26867982965544	FTL/GLUL/FTH1/STAT1/SLC25A4	1.9130262687821
Genetic Information Processing	Information processing in viruses	hsa03250	Viral life cycle - HIV-1	3/123	73/9376	3.13264283327765	SAMHD1/BST2/CCR5	2.1089435735691
Cellular Processes	Transport and catabolism	hsa04140	Autophagy - animal	5/123	169/9376	2.25525568865156	CTSD/OPTN/CTSL/RPS27A/UBA52	1.89851219774719
Human Diseases	Cancer: specific types	hsa05212	Pancreatic cancer	3/123	77/9376	2.96990814063985	CCND1/RAC2/STAT1	2.0011061490881
Human Diseases	Immune disease	hsa05340	Primary immunodeficiency	2/123	38/9376	4.0119811724433	PTPRC/IL2RG	2.14493447289836
Human Diseases	Cancer: specific types	hsa05219	Bladder cancer	2/123	41/9376	3.71842157445965	CCND1/TYMP	2.01116863930237
Metabolism	Global and overview maps	hsa01232	Nucleotide metabolism	3/123	85/9376	2.69038737446198	TYMP/PNP/CMPK2	1.80493424946571
Cellular Processes	Cell growth and death	hsa04210	Apoptosis	4/123	137/9376	2.22562459201234	CTSD/CTSS/CTSL/CTSW	1.66610427720726
Human Diseases	Infectious disease: bacterial	hsa05135	Yersinia infection	4/123	138/9376	2.20949687757747	RAC2/WIPF1/PKN1/ITGA4	1.65025945094435
Environmental Information Processing	Signal transduction	hsa04371	Apelin signaling pathway	4/123	140/9376	2.17793263646922	CCND1/GNG11/CALM1/SPP1	1.61897231903792
Human Diseases	Cancer: overview	hsa05235	PD-L1 expression and PD-1 checkpoint pathway in cancer	3/123	90/9376	2.54092140921409	CD247/CD3G/STAT1	1.69349655331929
Human Diseases	Neurodegenerative disease	hsa05012	Parkinson disease	6/123	268/9376	1.70658900618857	UCHL1/SOD1/CALM1/RPS27A/UBA52/SLC25A4	1.35306816116153
Environmental Information Processing	Signal transduction	hsa04015	Rap1 signaling pathway	5/123	212/9376	1.79782175180242	RAC2/F2RL3/CALM1/ITGB2/ITGAL	1.35465335140292
Environmental Information Processing	Signal transduction	hsa04390	Hippo signaling pathway	4/123	157/9376	1.94210553570504	CCND1/WNT5A/ITGB2/ID2	1.37247482560308
Organismal Systems	Immune system	hsa04620	Toll-like receptor signaling pathway	3/123	109/9376	2.09800850302081	CCL5/SPP1/STAT1	1.32937125447302
Environmental Information Processing	Signal transduction	hsa04066	HIF-1 signaling pathway	3/123	110/9376	2.07893569844789	GAPDH/ENO1/ENO2	1.31232883130566
Environmental Information Processing	Signal transduction	hsa04350	TGF-beta signaling pathway	3/123	110/9376	2.07893569844789	LEFTY2/DCN/ID2	1.31232883130566
Human Diseases	Neurodegenerative disease	hsa05022	Pathways of neurodegeneration - multiple diseases	9/123	480/9376	1.42926829268293	UCHL1/OPTN/WNT5A/SOD1/CALM1/RPS27A/ACTR1A/UBA52/SLC25A4	1.11313786330764
Environmental Information Processing	Signal transduction	hsa04630	JAK-STAT signaling pathway	4/123	168/9376	1.81494386372435	CCND1/PRL/IL2RG/STAT1	1.22884354464031
Metabolism	Nucleotide metabolism	hsa00240	Pyrimidine metabolism	2/123	59/9376	2.58398787377704	TYMP/CMPK2	1.40713810382106
Environmental Information Processing	Signal transduction	hsa04370	VEGF signaling pathway	2/123	60/9376	2.54092140921409	RAC2/HSPB1	1.38050596429504
Organismal Systems	Digestive system	hsa04978	Mineral absorption	2/123	61/9376	2.49926695988271	FTL/FTH1	1.35440756564552
Environmental Information Processing	Signal transduction	hsa04151	PI3K-Akt signaling pathway	7/123	362/9376	1.47401518214077	CCND1/PRL/GNG11/IL2RG/SPP1/PKN1/ITGA4	1.0604365132426
Organismal Systems	Immune system	hsa04660	T cell receptor signaling pathway	3/123	122/9376	1.87445021991204	PTPRC/CD247/CD3G	1.12084916314628
Organismal Systems	Development and regeneration	hsa04360	Axon guidance	4/123	184/9376	1.6571226581831	RAC2/WNT5A/SEMA3A/MYL12A	1.03788027640491
Organismal Systems	Immune system	hsa04621	NOD-like receptor signaling pathway	4/123	187/9376	1.63053780270423	CCL5/STAT1/PKN1/GBP5	1.00414104451867
Cellular Processes	Transport and catabolism	hsa04142	Lysosome biogenesis	5/123	250/9376	1.52455284552846	CTSD/CTSS/LAPTM5/CTSL/CTSW	0.969205638911951
Human Diseases	Infectious disease: bacterial	hsa05131	Shigellosis	5/123	253/9376	1.50647514380282	CCL5/MYL12A/RPS27A/TNIP1/UBA52	0.941556687663313
Organismal Systems	Immune system	hsa04622	RIG-I-like receptor signaling pathway	2/123	72/9376	2.11743450767841	ISG15/IFIH1	1.09736319209936
Cellular Processes	Cell growth and death	hsa04115	p53 signaling pathway	2/123	75/9376	2.03273712737127	CCND1/IGFBP3	1.03526733849401
Metabolism	Amino acid metabolism	hsa00220	Arginine biosynthesis	1/123	23/9376	3.31424531636621	GLUL	1.28113459015104
Human Diseases	Cancer: specific types	hsa05214	Glioma	2/123	76/9376	2.00599058622165	CCND1/CALM1	1.01521061817107
Genetic Information Processing	Folding, sorting and degradation	hsa03018	RNA degradation	2/123	78/9376	1.95455493016469	ENO1/ENO2	0.9760012374952
Human Diseases	Cardiovascular disease	hsa05415	Diabetic cardiomyopathy	4/123	205/9376	1.48736862978386	GAPDH/CTSD/RAC2/SLC25A4	0.813435399575111
Metabolism	Xenobiotics biodegradation and metabolism	hsa00983	Drug metabolism - other enzymes	2/123	82/9376	1.85921078722982	TYMP/GSTT1	0.900953186902882
Cellular Processes	Cellular community - eukaryotes	hsa04550	Signaling pathways regulating pluripotency of stem cells	3/123	144/9376	1.58807588075881	LEFTY2/WNT5A/ID2	0.819905177090415
Human Diseases	Endocrine and metabolic disease	hsa04936	Alcoholic liver disease	3/123	144/9376	1.58807588075881	CCND1/C1QA/C1QB	0.819905177090415
Organismal Systems	Immune system	hsa04623	Cytosolic DNA-sensing pathway	2/123	83/9376	1.8368106572632	CCL5/SAMHD1	0.882846486543468
Human Diseases	Cancer: specific types	hsa05210	Colorectal cancer	2/123	87/9376	1.75235959256144	CCND1/RAC2	0.812825875123978
Organismal Systems	Sensory system	hsa04744	Phototransduction	1/123	29/9376	2.62853938884216	CALM1	1.0126469467056
Environmental Information Processing	Signaling molecules and interaction	hsa04512	ECM-receptor interaction	2/123	89/9376	1.71298072531287	SPP1/ITGA4	0.779169569294991
Organismal Systems	Nervous system	hsa04727	GABAergic synapse	2/123	89/9376	1.71298072531287	GLUL/GNG11	0.779169569294991
Human Diseases	Substance dependence	hsa05032	Morphine addiction	2/123	91/9376	1.67533279728402	GNG11/PDE2A	0.746353367278931
Metabolism	Carbohydrate metabolism	hsa00630	Glyoxylate and dicarboxylate metabolism	1/123	31/9376	2.45895620246525	GLUL	0.938059447138791
Genetic Information Processing	Folding, sorting and degradation	hsa03060	Protein export	1/123	31/9376	2.45895620246525	SEC11C	0.938059447138791
Cellular Processes	Cellular community - eukaryotes	hsa04520	Adherens junction	2/123	93/9376	1.63930413497683	RAC2/MYL12A	0.71433466398014
Environmental Information Processing	Signaling molecules and interaction	hsa04080	Neuroactive ligand-receptor interaction	6/123	370/9376	1.23612392880686	PRL/GZMA/ADM/F2RL3/PGRMC2/RXFP1	0.534283551649158
Organismal Systems	Environmental adaptation	hsa04713	Circadian entrainment	2/123	97/9376	1.57170396446232	GNG11/CALM1	0.652534377294062
Organismal Systems	Immune system	hsa04666	Fc gamma R-mediated phagocytosis	2/123	98/9376	1.55566616890659	PTPRC/RAC2	0.637524270036714
Organismal Systems	Endocrine system	hsa04925	Aldosterone synthesis and secretion	2/123	98/9376	1.55566616890659	CALM1/PDE2A	0.637524270036714
Metabolism	Carbohydrate metabolism	hsa00051	Fructose and mannose metabolism	1/123	35/9376	2.17793263646922	TPI1	0.804923679383404
Environmental Information Processing	Signal transduction	hsa04022	cGMP-PKG signaling pathway	3/123	166/9376	1.3776079929474	CALM1/PDE2A/SLC25A4	0.565929483703426
Human Diseases	Cardiovascular disease	hsa05410	Hypertrophic cardiomyopathy	2/123	99/9376	1.53995236922066	TTN/ITGA4	0.622681815472953
Metabolism	Glycan biosynthesis and metabolism	hsa00512	Mucin type O-glycan biosynthesis	1/123	36/9376	2.11743450767841	GALNT18	0.77445609825228
Environmental Information Processing	Signal transduction	hsa04014	Ras signaling pathway	4/123	238/9376	1.28113684498189	GNG11/RAC2/CALM1/ETS1	0.506497820877455
Organismal Systems	Endocrine system	hsa04916	Melanogenesis	2/123	101/9376	1.50945826289946	WNT5A/CALM1	0.593484322404756
Human Diseases	Endocrine and metabolic disease	hsa04933	AGE-RAGE signaling pathway in diabetic complications	2/123	101/9376	1.50945826289946	CCND1/STAT1	0.593484322404756
Cellular Processes	Cellular community - eukaryotes	hsa04530	Tight junction	3/123	170/9376	1.34519368723099	CCND1/MYL12A/SYNPO	0.523659194254405
Human Diseases	Cancer: specific types	hsa05225	Hepatocellular carcinoma	3/123	170/9376	1.34519368723099	CCND1/WNT5A/GSTT1	0.523659194254405
Metabolism	Amino acid metabolism	hsa00250	Alanine, aspartate and glutamate metabolism	1/123	37/9376	2.06020654801143	GLUL	0.74496877405934
Human Diseases	Infectious disease: parasitic	hsa05143	African trypanosomiasis	1/123	37/9376	2.06020654801143	HBB	0.74496877405934
Human Diseases	Cancer: specific types	hsa05216	Thyroid cancer	1/123	37/9376	2.06020654801143	CCND1	0.74496877405934
Human Diseases	Infectious disease: parasitic	hsa05146	Amoebiasis	2/123	103/9376	1.48014839371695	ITGB2/HSPB1	0.564912098064821
Metabolism	Metabolism of cofactors and vitamins	hsa00760	Nicotinate and nicotinamide metabolism	1/123	38/9376	2.00599058622165	PNP	0.716400191189664
Organismal Systems	Immune system	hsa04625	C-type lectin receptor signaling pathway	2/123	105/9376	1.45195509097948	CALM1/STAT1	0.536937275299211
Human Diseases	Cardiovascular disease	hsa05414	Dilated cardiomyopathy	2/123	105/9376	1.45195509097948	TTN/ITGA4	0.536937275299211
Environmental Information Processing	Signal transduction	hsa04310	Wnt signaling pathway	3/123	178/9376	1.28473554398465	CCND1/RAC2/WNT5A	0.44218285106421
Organismal Systems	Excretory system	hsa04962	Vasopressin-regulated water reabsorption	1/123	44/9376	1.73244641537324	ARHGDIB	0.561450850312323
Organismal Systems	Nervous system	hsa04724	Glutamatergic synapse	2/123	116/9376	1.31426969442108	GLUL/GNG11	0.392665655498705
Genetic Information Processing	Folding, sorting and degradation	hsa03050	Proteasome	1/123	46/9376	1.6571226581831	PSMB9	0.515088020013222
Organismal Systems	Nervous system	hsa04722	Neurotrophin signaling pathway	2/123	120/9376	1.27046070460705	CALM1/ARHGDIB	0.343779549405884
NA	NA	hsa03272	Virion - Hepatitis viruses	1/123	48/9376	1.58807588075881	CD9	0.470930296030476
Metabolism	Glycan biosynthesis and metabolism	hsa00514	Other types of O-glycan biosynthesis	1/123	49/9376	1.55566616890659	GALNT18	0.449612027584336
Organismal Systems	Endocrine system	hsa04919	Thyroid hormone signaling pathway	2/123	122/9376	1.24963347994136	CCND1/STAT1	0.319974162867396
Organismal Systems	Endocrine system	hsa04935	Growth hormone synthesis, secretion and action	2/123	122/9376	1.24963347994136	IGFBP3/STAT1	0.319974162867396
Environmental Information Processing	Signal transduction	hsa04071	Sphingolipid signaling pathway	2/123	125/9376	1.21964227642276	CTSD/RAC2	0.285018805111566
Human Diseases	Cancer: overview	hsa05202	Transcriptional misregulation in cancer	3/123	201/9376	1.13772600412571	IGFBP3/ID2/BMP2K	0.227566249748367
Metabolism	Nucleotide metabolism	hsa00230	Purine metabolism	2/123	128/9376	1.19105691056911	PNP/PDE2A	0.250923154088243
Organismal Systems	Endocrine system	hsa04926	Relaxin signaling pathway	2/123	130/9376	1.17273295809881	GNG11/RXFP1	0.228647709385259
Organismal Systems	Nervous system	hsa04728	Dopaminergic synapse	2/123	133/9376	1.1462803349838	GNG11/CALM1	0.195885460999308
Environmental Information Processing	Signal transduction	hsa04340	Hedgehog signaling pathway	1/123	56/9376	1.36120789779326	CCND1	0.31256490082156
Human Diseases	Infectious disease: bacterial	hsa05134	Legionellosis	1/123	56/9376	1.36120789779326	ITGB2	0.31256490082156
Organismal Systems	Circulatory system	hsa04270	Vascular smooth muscle contraction	2/123	134/9376	1.13772600412571	ADM/CALM1	0.185132334388222
Metabolism	Metabolism of other amino acids	hsa00480	Glutathione metabolism	1/123	59/9376	1.29199393688852	GSTT1	0.259393270291155
Human Diseases	Cancer: specific types	hsa05213	Endometrial cancer	1/123	59/9376	1.29199393688852	CCND1	0.259393270291155
Organismal Systems	Endocrine system	hsa04915	Estrogen signaling pathway	2/123	139/9376	1.09680060829385	CTSD/CALM1	0.132561352837633
Genetic Information Processing	Folding, sorting and degradation	hsa04120	Ubiquitin mediated proteolysis	2/123	142/9376	1.07362876445666	RPS27A/UBA52	0.101928037547745
Organismal Systems	Aging	hsa04213	Longevity regulating pathway - multiple species	1/123	62/9376	1.22947810123263	SOD1	0.209009433689099
Human Diseases	Cancer: specific types	hsa05217	Basal cell carcinoma	1/123	63/9376	1.20996257581623	WNT5A	0.192781021928976
Human Diseases	Cancer: overview	hsa05208	Chemical carcinogenesis - reactive oxygen species	3/123	227/9376	1.00741377457827	SOD1/GSTT1/SLC25A4	0.0130365418891073
Organismal Systems	Endocrine system	hsa04929	GnRH secretion	1/123	65/9376	1.17273295809881	SPP1	0.161113019971621
Human Diseases	Cancer: specific types	hsa05224	Breast cancer	2/123	148/9376	1.03010327400571	CCND1/WNT5A	0.0425586368665884
Organismal Systems	Nervous system	hsa04720	Long-term potentiation	1/123	67/9376	1.13772600412571	CALM1	0.130436382731301
Human Diseases	Cancer: specific types	hsa05226	Gastric cancer	2/123	150/9376	1.01636856368564	CCND1/WNT5A	0.0232994886471966
Metabolism	Metabolism of cofactors and vitamins	hsa00830	Retinol metabolism	1/123	68/9376	1.12099473935916	CYP26B1	0.115448865690675
Human Diseases	Cancer: specific types	hsa05221	Acute myeloid leukemia	1/123	68/9376	1.12099473935916	CCND1	0.115448865690675
Organismal Systems	Immune system	hsa04664	Fc epsilon RI signaling pathway	1/123	69/9376	1.10474843878874	RAC2	0.100684857569365
Organismal Systems	Endocrine system	hsa04924	Renin secretion	1/123	69/9376	1.10474843878874	CALM1	0.100684857569365
Human Diseases	Substance dependence	hsa05031	Amphetamine addiction	1/123	69/9376	1.10474843878874	CALM1	0.100684857569365
Organismal Systems	Endocrine system	hsa04921	Oxytocin signaling pathway	2/123	154/9376	0.989969380213283	CCND1/CALM1	-0.0144701316706198
Human Diseases	Cancer: overview	hsa05204	Chemical carcinogenesis - DNA adducts	1/123	70/9376	1.08896631823461	GSTT1	0.0861370565154187
Human Diseases	Cancer: specific types	hsa05211	Renal cell carcinoma	1/123	70/9376	1.08896631823461	ETS1	0.0861370565154187
Human Diseases	Endocrine and metabolic disease	hsa04934	Cushing syndrome	2/123	155/9376	0.9835824809861	CCND1/WNT5A	-0.0237619062915437
Human Diseases	Infectious disease: bacterial	hsa05120	Epithelial cell signaling in Helicobacter pylori infection	1/123	71/9376	1.07362876445666	CCL5	0.071798506626891
Human Diseases	Infectious disease: viral	hsa05160	Hepatitis C	2/123	156/9376	0.977277465082343	CCND1/STAT1	-0.0329951822056333
Cellular Processes	Transport and catabolism	hsa04148	Efferocytosis	2/123	157/9376	0.971052767852519	C1QA/C1QB	-0.0421708034690332
Metabolism	Xenobiotics biodegradation and metabolism	hsa00982	Drug metabolism - cytochrome P450	1/123	73/9376	1.04421427775922	GSTT1	0.043722941078225
Human Diseases	Cancer: specific types	hsa05218	Melanoma	1/123	73/9376	1.04421427775922	CCND1	0.043722941078225
Human Diseases	Cancer: specific types	hsa05223	Non-small cell lung cancer	1/123	73/9376	1.04421427775922	CCND1	0.043722941078225
Human Diseases	Drug resistance: antineoplastic	hsa01524	Platinum drug resistance	1/123	75/9376	1.01636856368564	GSTT1	0.0164086667484617
Human Diseases	Infectious disease: viral	hsa05161	Hepatitis B	2/123	163/9376	0.935308494189236	STAT1/IFIH1	-0.0960588625326704
Organismal Systems	Digestive system	hsa04971	Gastric acid secretion	1/123	76/9376	1.00299529311083	CALM1	0.00302274535397597
Human Diseases	Cancer: specific types	hsa05220	Chronic myeloid leukemia	1/123	77/9376	0.989969380213283	CCND1	-0.0101894776310966
Metabolism	Carbohydrate metabolism	hsa00562	Inositol phosphate metabolism	1/123	78/9376	0.977277465082343	TPI1	-0.0232330497678482
Human Diseases	Infectious disease: bacterial	hsa05100	Bacterial invasion of epithelial cells	1/123	78/9376	0.977277465082343	CAV1	-0.0232330497678482
Metabolism	Xenobiotics biodegradation and metabolism	hsa00980	Metabolism of xenobiotics by cytochrome P450	1/123	79/9376	0.964906864258516	GSTT1	-0.0361128047048537
Environmental Information Processing	Signal transduction	hsa04020	Calcium signaling pathway	3/123	254/9376	0.900326483579796	SLN/CALM1/SLC25A4	-0.185672898595012
Cellular Processes	Transport and catabolism	hsa04146	Peroxisome	1/123	83/9376	0.9184053286316	SOD1	-0.0860834745745883
Human Diseases	Cardiovascular disease	hsa05412	Arrhythmogenic right ventricular cardiomyopathy	1/123	86/9376	0.886367933446776	ITGA4	-0.122050394199705
Organismal Systems	Immune system	hsa04662	B cell receptor signaling pathway	1/123	91/9376	0.837666398642008	RAC2	-0.179405221371321
Organismal Systems	Endocrine system	hsa04912	GnRH signaling pathway	1/123	93/9376	0.819652067488417	CALM1	-0.201514072445102
Organismal Systems	Digestive system	hsa04970	Salivary secretion	1/123	93/9376	0.819652067488417	CALM1	-0.201514072445102
Human Diseases	Cancer: specific types	hsa05222	Small cell lung cancer	1/123	93/9376	0.819652067488417	CCND1	-0.201514072445102
Human Diseases	Substance dependence	hsa05034	Alcoholism	2/123	191/9376	0.798195207082961	GNG11/CALM1	-0.32486692133092
Cellular Processes	Cell motility	hsa04814	Motor proteins	2/123	194/9376	0.785851982231162	MYL12A/ACTR1A	-0.347490705141273
Environmental Information Processing	Signal transduction	hsa04070	Phosphatidylinositol signaling system	1/123	98/9376	0.777833084453293	CALM1	-0.254895490468546
Human Diseases	Drug resistance: antineoplastic	hsa01522	Endocrine resistance	1/123	99/9376	0.769976184610331	CCND1	-0.265267188614409
Organismal Systems	Sensory system	hsa04750	Inflammatory mediator regulation of TRP channels	1/123	99/9376	0.769976184610331	CALM1	-0.265267188614409
Human Diseases	Cancer: overview	hsa05231	Choline metabolism in cancer	1/123	99/9376	0.769976184610331	RAC2	-0.265267188614409
Human Diseases	Infectious disease: bacterial	hsa05130	Pathogenic Escherichia coli infection	2/123	200/9376	0.762276422764228	GAPDH/WIPF1	-0.391793715120501
Environmental Information Processing	Signal transduction	hsa04064	NF-kappa B signaling pathway	1/123	105/9376	0.725977545489741	CCL21	-0.325547544506409
Human Diseases	Neurodegenerative disease	hsa05010	Alzheimer disease	4/123	388/9376	0.785851982231162	GAPDH/WNT5A/CALM1/SLC25A4	-0.496701306705607
Human Diseases	Cancer: specific types	hsa05215	Prostate cancer	1/123	106/9376	0.719128700720969	CCND1	-0.335287483825612
Organismal Systems	Endocrine system	hsa04922	Glucagon signaling pathway	1/123	107/9376	0.712407871742269	CALM1	-0.344944603748336
Human Diseases	Neurodegenerative disease	hsa05016	Huntington disease	3/123	308/9376	0.742477035159962	SOD1/ACTR1A/SLC25A4	-0.529825039357201
Human Diseases	Cardiovascular disease	hsa05417	Lipid and atherosclerosis	2/123	216/9376	0.70581150255947	CCL5/CALM1	-0.504314830447791
Human Diseases	Cancer: overview	hsa05207	Chemical carcinogenesis - receptor activation	2/123	217/9376	0.702558914990072	CCND1/GSTT1	-0.511097441475517
Organismal Systems	Nervous system	hsa04725	Cholinergic synapse	1/123	115/9376	0.662849063273241	GNG11	-0.41941239540521
Organismal Systems	Nervous system	hsa04726	Serotonergic synapse	1/123	115/9376	0.662849063273241	GNG11	-0.41941239540521
NA	NA	hsa04081	Hormone signaling	2/123	219/9376	0.696142851839477	PRL/GNG11	-0.524580110955492
Environmental Information Processing	Signal transduction	hsa04668	TNF signaling pathway	1/123	119/9376	0.640568422490947	CCL5	-0.454937242211412
Environmental Information Processing	Signal transduction	hsa04024	cAMP signaling pathway	2/123	226/9376	0.674580905101086	RAC2/CALM1	-0.57093099151246
Environmental Information Processing	Signal transduction	hsa04152	AMPK signaling pathway	1/123	122/9376	0.624816739970678	CCND1	-0.48090083741149
Environmental Information Processing	Signal transduction	hsa04068	FoxO signaling pathway	1/123	133/9376	0.5731401674919	CCND1	-0.571612275034753
Metabolism	Energy metabolism	hsa00190	Oxidative phosphorylation	1/123	138/9376	0.552374219394368	COX17	-0.61074872422188
Cellular Processes	Cell growth and death	hsa04114	Oocyte meiosis	1/123	138/9376	0.552374219394368	CALM1	-0.61074872422188
Organismal Systems	Endocrine system	hsa04910	Insulin signaling pathway	1/123	138/9376	0.552374219394368	CALM1	-0.61074872422188
Organismal Systems	Development and regeneration	hsa04380	Osteoclast differentiation	1/123	142/9376	0.536814382228329	STAT1	-0.64121137150953
Human Diseases	Neurodegenerative disease	hsa05017	Spinocerebellar ataxia	1/123	144/9376	0.529358626919603	SLC25A4	-0.656176032663757
Organismal Systems	Nervous system	hsa04723	Retrograde endocannabinoid signaling	1/123	149/9376	0.511594914606864	GNG11	-0.692851184881854
Human Diseases	Neurodegenerative disease	hsa05014	Amyotrophic lateral sclerosis	3/123	368/9376	0.621420996818664	OPTN/SOD1/ACTR1A	-0.854207060501865
Metabolism	Global and overview maps	hsa01240	Biosynthesis of cofactors	1/123	154/9376	0.494984690106641	CMPK2	-0.728533050321836
Organismal Systems	Circulatory system	hsa04261	Adrenergic signaling in cardiomyocytes	1/123	154/9376	0.494984690106641	CALM1	-0.728533050321836
Cellular Processes	Cell growth and death	hsa04110	Cell cycle	1/123	158/9376	0.482453432129258	CCND1	-0.756408738274198
Environmental Information Processing	Signal transduction	hsa04150	mTOR signaling pathway	1/123	158/9376	0.482453432129258	WNT5A	-0.756408738274198
Environmental Information Processing	Signal transduction	hsa04010	MAPK signaling pathway	2/123	300/9376	0.508184281842818	RAC2/HSPB1	-0.998188819285405
NA	NA	hsa04082	Neuroactive ligand signaling	1/123	199/9376	0.383053478775994	GNG11	-1.01419299112518
NA	NA	hsa04382	Cornified envelope formation	1/123	217/9376	0.351279457495036	S100A10	-1.11470615935868
Organismal Systems	Environmental adaptation	hsa04714	Thermogenesis	1/123	235/9376	0.324372945857118	COX17	-1.20931940359581
NA	NA	hsa04519	Cadherin signaling	2/123	404/9376	0.377364565724865	RAC2/WNT5A	-1.47494829351758
Organismal Systems	Sensory system	hsa04740	Olfactory transduction	2/123	449/9376	0.339544063592084	CALM1/PDE2A	-1.65352651755591
Human Diseases	Cancer: overview	hsa05206	MicroRNAs in cancer	1/123	323/9376	0.235998892496665	CCND1	-1.61100134108524