ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0003823 antigen binding 23/186 174/18639 0.132183908045977 13.246106785317 1.88058903715396e-19 8.81996258425205e-17 GO:0042605 peptide antigen binding 8/186 45/18639 0.177777777777778 17.8150537634409 1.32971728390596e-08 3.11818703075948e-06 GO:0034987 immunoglobulin receptor binding 6/186 19/18639 0.315789473684211 31.6451612903226 2.21866670075914e-08 3.46851560885345e-06 GO:0042608 T cell receptor binding 4/186 11/18639 0.363636363636364 36.4398826979472 2.99979297489574e-06 0.000351725726306526 GO:0048020 CCR chemokine receptor binding 6/186 50/18639 0.12 12.0251612903226 1.00513835325034e-05 0.000942819775348818 GO:0023023 MHC protein complex binding 5/186 37/18639 0.135135135135135 13.5418482999128 3.1543862662652e-05 0.00246567859813063 GO:0042277 peptide binding 11/186 249/18639 0.0441767068273092 4.42693354061407 4.24689445873073e-05 0.00284541928734959 GO:0042379 chemokine receptor binding 6/186 72/18639 0.0833333333333333 8.3508064516129 8.24174279920389e-05 0.00431921973064933 GO:0008009 chemokine activity 5/186 45/18639 0.111111111111111 11.1344086021505 8.28848135945501e-05 0.00431921973064933 GO:0023026 MHC class II protein complex binding 4/186 27/18639 0.148148148148148 14.8458781362007 0.000140791957838935 0.00660314282264605 GO:0001968 fibronectin binding 4/186 30/18639 0.133333333333333 13.3612903225806 0.000214774335440534 0.00846604230559939 GO:0005178 integrin binding 8/186 161/18639 0.0496894409937888 4.97936285313564 0.000216615154940709 0.00846604230559939 GO:0005201 extracellular matrix structural constituent 8/186 168/18639 0.0476190476190476 4.77188940092166 0.000289182367669326 0.0104328100336088 GO:0019956 chemokine binding 4/186 33/18639 0.121212121212121 12.1466275659824 0.000313291970870978 0.0104952810241778 GO:0003735 structural constituent of ribosome 8/186 175/18639 0.0457142857142857 4.58101382488479 0.000380513871618838 0.0112360276914034 GO:0031386 protein tag activity 3/186 15/18639 0.2 20.041935483871 0.000407276057044475 0.0112360276914034 GO:0141047 molecular tag activity 3/186 15/18639 0.2 20.041935483871 0.000407276057044475 0.0112360276914034 GO:0043394 proteoglycan binding 4/186 37/18639 0.108108108108108 10.8334786399303 0.000490173054068733 0.0127717312421242 GO:0005125 cytokine activity 9/186 234/18639 0.0384615384615385 3.85421836228288 0.000586563299195244 0.0144788519643458 GO:0140375 immune receptor activity 7/186 156/18639 0.0448717948717949 4.49658808933003 0.000982647364642092 0.0230430807008571 GO:0019887 protein kinase regulator activity 9/186 255/18639 0.0352941176470588 3.53681214421252 0.00107790313562496 0.0240731700289575 GO:0004197 cysteine-type endopeptidase activity 5/186 88/18639 0.0568181818181818 5.69373167155425 0.00188191253857376 0.0390113734254187 GO:0001848 complement binding 3/186 25/18639 0.12 12.0251612903226 0.0019131377159587 0.0390113734254187 GO:0001637 G protein-coupled chemoattractant receptor activity 3/186 26/18639 0.115384615384615 11.5626550868486 0.00214691146994815 0.0395605912163334 GO:0004950 chemokine receptor activity 3/186 26/18639 0.115384615384615 11.5626550868486 0.00214691146994815 0.0395605912163334 GO:0140313 molecular sequestering activity 4/186 55/18639 0.0727272727272727 7.28797653958944 0.00220177537439474 0.0395605912163334 GO:0051087 protein-folding chaperone binding 6/186 134/18639 0.0447761194029851 4.48700048146365 0.00227747540051387 0.0395605912163334 GO:0019207 kinase regulator activity 9/186 287/18639 0.0313588850174216 3.14246375182646 0.00242167738763267 0.0405630962428473 GO:0001664 G protein-coupled receptor binding 9/186 297/18639 0.0303030303030303 3.0366568914956 0.0030422672389201 0.0492008046570182 GO:0015026 coreceptor activity 4/186 61/18639 0.0655737704918033 6.57112638815442 0.00321653684348197 0.0502851926531014 GO:0032395 MHC class II receptor activity 2/186 10/18639 0.2 20.041935483871 0.00422858972303455 0.0639744703259098 GO:0001851 complement component C3b binding 2/186 11/18639 0.181818181818182 18.2199413489736 0.00513447495185596 0.0729717803763771 GO:0008199 ferric iron binding 2/186 11/18639 0.181818181818182 18.2199413489736 0.00513447495185596 0.0729717803763771 GO:0042301 phosphate ion binding 2/186 12/18639 0.166666666666667 16.7016129032258 0.00612110593083492 0.0844352553400464 GO:0005126 cytokine receptor binding 8/186 275/18639 0.0290909090909091 2.91519061583578 0.00649605708011809 0.0870471648735824 GO:0031432 titin binding 2/186 13/18639 0.153846153846154 15.4168734491315 0.00718679855563523 0.0910975276376466 GO:0031994 insulin-like growth factor I binding 2/186 13/18639 0.153846153846154 15.4168734491315 0.00718679855563523 0.0910975276376466 GO:0016835 carbon-oxygen lyase activity 4/186 79/18639 0.0506329113924051 5.07390771743569 0.00806420847187052 0.0995293098238757 GO:0030547 signaling receptor inhibitor activity 3/186 44/18639 0.0681818181818182 6.8324780058651 0.00959237012509455 0.11535439970947 GO:0016209 antioxidant activity 4/186 86/18639 0.0465116279069767 4.6609152288072 0.0108028907379314 0.124019410037848 GO:0016722 oxidoreductase activity, acting on metal ions 2/186 16/18639 0.125 12.5262096774194 0.0108417821141829 0.124019410037848 GO:0008234 cysteine-type peptidase activity 6/186 187/18639 0.0320855614973262 3.21528376746593 0.011301314593167 0.126198012957031 GO:0044325 transmembrane transporter binding 5/186 136/18639 0.0367647058823529 3.68417931688805 0.011809011076364 0.127228031744148 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 2/186 17/18639 0.117647058823529 11.7893738140417 0.0122073804445345 0.127228031744148 GO:0019198 transmembrane receptor protein phosphatase activity 2/186 17/18639 0.117647058823529 11.7893738140417 0.0122073804445345 0.127228031744148 GO:0001222 transcription corepressor binding 3/186 49/18639 0.0612244897959184 6.13528637261356 0.0128696119413722 0.128422297883054 GO:0016763 pentosyltransferase activity 3/186 49/18639 0.0612244897959184 6.13528637261356 0.0128696119413722 0.128422297883054 GO:0019955 cytokine binding 5/186 144/18639 0.0347222222222222 3.47950268817204 0.0148162539368626 0.139321322064901 GO:0005080 protein kinase C binding 3/186 52/18639 0.0576923076923077 5.78132754342432 0.0151062862193384 0.139321322064901 GO:0005520 insulin-like growth factor binding 2/186 19/18639 0.105263157894737 10.5483870967742 0.0151500797981023 0.139321322064901 GO:0043395 heparan sulfate proteoglycan binding 2/186 19/18639 0.105263157894737 10.5483870967742 0.0151500797981023 0.139321322064901 GO:0004896 cytokine receptor activity 4/186 96/18639 0.0416666666666667 4.17540322580645 0.0156576021608194 0.139530778294895 GO:0044389 ubiquitin-like protein ligase binding 8/186 322/18639 0.0248447204968944 2.48968142656782 0.0157678704682931 0.139530778294895 GO:0001846 opsonin binding 2/186 21/18639 0.0952380952380952 9.54377880184332 0.0183646492786465 0.156600372939731 GO:0072542 protein phosphatase activator activity 2/186 21/18639 0.0952380952380952 9.54377880184332 0.0183646492786465 0.156600372939731 GO:0004601 peroxidase activity 3/186 57/18639 0.0526315789473684 5.2741935483871 0.0192920452611976 0.16157087906253 GO:0030021 extracellular matrix structural constituent conferring compression resistance 2/186 22/18639 0.0909090909090909 9.1099706744868 0.02007017158198 0.165138780209625 GO:0004175 endopeptidase activity 9/186 405/18639 0.0222222222222222 2.22688172043011 0.0207041385465903 0.167417947902601 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 3/186 59/18639 0.0508474576271186 5.09540732640787 0.0211277980252922 0.167911611570357 GO:0004602 glutathione peroxidase activity 2/186 23/18639 0.0869565217391304 8.71388499298738 0.021839250118959 0.167911611570357 GO:0016493 C-C chemokine receptor activity 2/186 23/18639 0.0869565217391304 8.71388499298738 0.021839250118959 0.167911611570357 GO:0004866 endopeptidase inhibitor activity 5/186 161/18639 0.031055900621118 3.11210178320978 0.0228169731741976 0.17079148013671 GO:0016836 hydro-lyase activity 3/186 61/18639 0.0491803278688525 4.92834479111581 0.0230560881432104 0.17079148013671 GO:0019957 C-C chemokine binding 2/186 24/18639 0.0833333333333333 8.3508064516129 0.0236704609997572 0.17079148013671 GO:0035035 histone acetyltransferase binding 2/186 24/18639 0.0833333333333333 8.3508064516129 0.0236704609997572 0.17079148013671 GO:0004857 enzyme inhibitor activity 9/186 416/18639 0.0216346153846154 2.16799782878412 0.0240985563120098 0.171245801671706 GO:0005507 copper ion binding 3/186 63/18639 0.0476190476190476 4.77188940092166 0.0250769232660493 0.174377324841033 GO:0019211 phosphatase activator activity 2/186 25/18639 0.08 8.01677419354839 0.0255624021548701 0.174377324841033 GO:0061134 peptidase regulator activity 6/186 226/18639 0.0265486725663717 2.66043391378818 0.0260967168334072 0.174377324841033 GO:0038024 cargo receptor activity 3/186 65/18639 0.0461538461538462 4.62506203473945 0.0271901892551006 0.174377324841033 GO:0030414 peptidase inhibitor activity 5/186 169/18639 0.029585798816568 2.96478335560221 0.0273929836714455 0.174377324841033 GO:0004435 phosphatidylinositol phospholipase C activity 2/186 26/18639 0.0769230769230769 7.70843672456576 0.0275136930452803 0.174377324841033 GO:0008198 ferrous iron binding 2/186 26/18639 0.0769230769230769 7.70843672456576 0.0275136930452803 0.174377324841033 GO:0070412 R-SMAD binding 2/186 26/18639 0.0769230769230769 7.70843672456576 0.0275136930452803 0.174377324841033 GO:0050840 extracellular matrix binding 3/186 67/18639 0.0447761194029851 4.48700048146365 0.0293956566006916 0.183820839276325 GO:0031625 ubiquitin protein ligase binding 7/186 302/18639 0.0231788079470199 2.32274086733604 0.0322143869234204 0.198796677198476 GO:0004629 phospholipase C activity 2/186 29/18639 0.0689655172413793 6.91101223581757 0.0337101757083245 0.205325615677976 GO:0005518 collagen binding 3/186 72/18639 0.0416666666666667 4.17540322580645 0.0353102305674757 0.21231407866854 GO:0048019 receptor antagonist activity 2/186 30/18639 0.0666666666666667 6.68064516129032 0.0358854808136266 0.213041651918872 GO:0061135 endopeptidase regulator activity 5/186 184/18639 0.0271739130434783 2.72308906030856 0.0374581115027552 0.219598178684902 GO:0140311 protein sequestering activity 2/186 33/18639 0.0606060606060606 6.0733137829912 0.0427229473467673 0.247371139575727 GO:0046332 SMAD binding 3/186 79/18639 0.0379746835443038 3.80543078807677 0.0445388110682754 0.254740273061234 GO:0019838 growth factor binding 4/186 136/18639 0.0294117647058824 2.94734345351044 0.0474857553025665 0.268323123336189 GO:0003924 GTPase activity 7/186 331/18639 0.0211480362537764 2.11923789104376 0.0486853476381788 0.271826524313165 GO:0001540 amyloid-beta binding 3/186 83/18639 0.036144578313253 3.62203653322969 0.0502977227455346 0.276559125381803 GO:0030295 protein kinase activator activity 4/186 139/18639 0.0287769784172662 2.88373172429798 0.0507123342917591 0.276559125381803 GO:0004860 protein kinase inhibitor activity 3/186 84/18639 0.0357142857142857 3.57891705069124 0.0517914532009702 0.279197604037414 GO:0003714 transcription corepressor activity 5/186 204/18639 0.0245098039215686 2.45611954459203 0.0540081488898525 0.287049434804232 GO:0005501 retinoid binding 2/186 38/18639 0.0526315789473684 5.2741935483871 0.0550841132886585 0.287049434804232 GO:0019840 isoprenoid binding 2/186 38/18639 0.0526315789473684 5.2741935483871 0.0550841132886585 0.287049434804232 GO:0008081 phosphoric diester hydrolase activity 3/186 87/18639 0.0344827586206897 3.45550611790879 0.05640014056711 0.290677647538182 GO:0019209 kinase activator activity 4/186 148/18639 0.027027027027027 2.70836965998256 0.0610952292483808 0.308617568786586 GO:0019210 kinase inhibitor activity 3/186 90/18639 0.0333333333333333 3.34032258064516 0.0611970872007516 0.308617568786586 GO:0042056 chemoattractant activity 2/186 42/18639 0.0476190476190476 4.77188940092166 0.0657585385882525 0.328093134020111 GO:0008200 ion channel inhibitor activity 2/186 43/18639 0.0465116279069767 4.6609152288072 0.0685270815868606 0.338307381728817 GO:0016248 channel inhibitor activity 2/186 44/18639 0.0454545454545455 4.5549853372434 0.0713334964183732 0.348493852293928 GO:0141110 transporter inhibitor activity 2/186 45/18639 0.0444444444444444 4.45376344086022 0.074176761052366 0.358648463232574 GO:0099106 ion channel regulator activity 4/186 160/18639 0.025 2.50524193548387 0.0765492916835097 0.366343038771082 GO:0016247 channel regulator activity 4/186 168/18639 0.0238095238095238 2.38594470046083 0.0878410595869852 0.416135928750465 GO:0005006 epidermal growth factor receptor activity 2/186 50/18639 0.04 4.00838709677419 0.0889111978179993 0.416993517766417 GO:0141108 transporter regulator activity 4/186 170/18639 0.0235294117647059 2.35787476280835 0.0907836578416338 0.418368968801057 GO:0005539 glycosaminoglycan binding 5/186 242/18639 0.0206611570247934 2.07044788056518 0.0954232857338802 0.418368968801057 GO:0005345 purine nucleobase transmembrane transporter activity 1/186 10/18639 0.1 10.0209677419355 0.0954487839268936 0.418368968801057 GO:0005522 profilin binding 1/186 10/18639 0.1 10.0209677419355 0.0954487839268936 0.418368968801057 GO:0008297 single-stranded DNA exodeoxyribonuclease activity 1/186 10/18639 0.1 10.0209677419355 0.0954487839268936 0.418368968801057 GO:0008401 retinoic acid 4-hydroxylase activity 1/186 10/18639 0.1 10.0209677419355 0.0954487839268936 0.418368968801057 GO:0031720 haptoglobin binding 1/186 10/18639 0.1 10.0209677419355 0.0954487839268936 0.418368968801057 GO:0004252 serine-type endopeptidase activity 4/186 176/18639 0.0227272727272727 2.2774926686217 0.0998905492433797 0.426097571762107 GO:0140104 molecular carrier activity 5/186 249/18639 0.0200803212851406 2.01224251846094 0.104432625224877 0.426097571762107 GO:0010854 adenylate cyclase regulator activity 1/186 11/18639 0.0909090909090909 9.1099706744868 0.104480214824397 0.426097571762107 GO:0015205 nucleobase transmembrane transporter activity 1/186 11/18639 0.0909090909090909 9.1099706744868 0.104480214824397 0.426097571762107 GO:0015217 ADP transmembrane transporter activity 1/186 11/18639 0.0909090909090909 9.1099706744868 0.104480214824397 0.426097571762107 GO:0034511 U3 snoRNA binding 1/186 11/18639 0.0909090909090909 9.1099706744868 0.104480214824397 0.426097571762107 GO:0050998 nitric-oxide synthase binding 1/186 11/18639 0.0909090909090909 9.1099706744868 0.104480214824397 0.426097571762107 GO:0097493 structural molecule activity conferring elasticity 1/186 11/18639 0.0909090909090909 9.1099706744868 0.104480214824397 0.426097571762107 GO:0001221 transcription coregulator binding 3/186 115/18639 0.0260869565217391 2.61416549789621 0.107895409931886 0.436023733494894 GO:0019208 phosphatase regulator activity 3/186 117/18639 0.0256410256410256 2.56947890818859 0.112100507740735 0.436023733494894 GO:1990782 protein tyrosine kinase binding 3/186 117/18639 0.0256410256410256 2.56947890818859 0.112100507740735 0.436023733494894 GO:0004875 complement receptor activity 1/186 12/18639 0.0833333333333333 8.3508064516129 0.11342195199654 0.436023733494894 GO:0010853 cyclase activator activity 1/186 12/18639 0.0833333333333333 8.3508064516129 0.11342195199654 0.436023733494894 GO:0015166 polyol transmembrane transporter activity 1/186 12/18639 0.0833333333333333 8.3508064516129 0.11342195199654 0.436023733494894 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 1/186 12/18639 0.0833333333333333 8.3508064516129 0.11342195199654 0.436023733494894 GO:0015459 potassium channel regulator activity 2/186 59/18639 0.0338983050847458 3.39693821760525 0.117317112387308 0.447331103330467 GO:0004714 transmembrane receptor protein tyrosine kinase activity 2/186 60/18639 0.0333333333333333 3.34032258064516 0.120601137900473 0.451550546456896 GO:0003697 single-stranded DNA binding 3/186 121/18639 0.0247933884297521 2.48453745667822 0.12069494128057 0.451550546456896 GO:0019855 calcium channel inhibitor activity 1/186 13/18639 0.0769230769230769 7.70843672456576 0.122274881449948 0.451550546456896 GO:0039706 co-receptor binding 1/186 13/18639 0.0769230769230769 7.70843672456576 0.122274881449948 0.451550546456896 GO:0008236 serine-type peptidase activity 4/186 194/18639 0.0206185567010309 2.06617891586299 0.129588044259625 0.453547017317894 GO:0005344 oxygen carrier activity 1/186 14/18639 0.0714285714285714 7.15783410138249 0.131039880486258 0.453547017317894 GO:0005347 ATP transmembrane transporter activity 1/186 14/18639 0.0714285714285714 7.15783410138249 0.131039880486258 0.453547017317894 GO:0008191 metalloendopeptidase inhibitor activity 1/186 14/18639 0.0714285714285714 7.15783410138249 0.131039880486258 0.453547017317894 GO:0016530 metallochaperone activity 1/186 14/18639 0.0714285714285714 7.15783410138249 0.131039880486258 0.453547017317894 GO:0032036 myosin heavy chain binding 1/186 14/18639 0.0714285714285714 7.15783410138249 0.131039880486258 0.453547017317894 GO:0042826 histone deacetylase binding 3/186 127/18639 0.0236220472440945 2.36715773431547 0.134022665064458 0.453547017317894 GO:0017171 serine hydrolase activity 4/186 198/18639 0.0202020202020202 2.02443792766373 0.136639267445506 0.453547017317894 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 6/186 349/18639 0.0171919770773639 1.72280247712358 0.137205059569672 0.453547017317894 GO:0004089 carbonate dehydratase activity 1/186 15/18639 0.0666666666666667 6.68064516129032 0.139717817787174 0.453547017317894 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 1/186 15/18639 0.0666666666666667 6.68064516129032 0.139717817787174 0.453547017317894 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 1/186 15/18639 0.0666666666666667 6.68064516129032 0.139717817787174 0.453547017317894 GO:0005402 carbohydrate:monoatomic cation symporter activity 1/186 15/18639 0.0666666666666667 6.68064516129032 0.139717817787174 0.453547017317894 GO:0008242 omega peptidase activity 1/186 15/18639 0.0666666666666667 6.68064516129032 0.139717817787174 0.453547017317894 GO:0030553 cGMP binding 1/186 15/18639 0.0666666666666667 6.68064516129032 0.139717817787174 0.453547017317894 GO:0033130 acetylcholine receptor binding 1/186 15/18639 0.0666666666666667 6.68064516129032 0.139717817787174 0.453547017317894 GO:0051371 muscle alpha-actinin binding 1/186 15/18639 0.0666666666666667 6.68064516129032 0.139717817787174 0.453547017317894 GO:0016829 lyase activity 4/186 200/18639 0.02 2.0041935483871 0.14022242539679 0.453547017317894 GO:0016500 protein-hormone receptor activity 2/186 67/18639 0.0298507462686567 2.9913336543091 0.144179442277713 0.46315177005649 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 1/186 16/18639 0.0625 6.26310483870968 0.148309553498707 0.463714537272623 GO:0008142 oxysterol binding 1/186 16/18639 0.0625 6.26310483870968 0.148309553498707 0.463714537272623 GO:0008296 3'-5'-DNA exonuclease activity 1/186 16/18639 0.0625 6.26310483870968 0.148309553498707 0.463714537272623 GO:0019841 retinol binding 1/186 16/18639 0.0625 6.26310483870968 0.148309553498707 0.463714537272623 GO:0002020 protease binding 3/186 136/18639 0.0220588235294118 2.21050759013283 0.154907363580352 0.468450162665884 GO:0042578 phosphoric ester hydrolase activity 6/186 363/18639 0.0165289256198347 1.65635830445215 0.156109882553199 0.468450162665884 GO:0004550 nucleoside diphosphate kinase activity 1/186 17/18639 0.0588235294117647 5.89468690702087 0.156815939314592 0.468450162665884 GO:0005092 GDP-dissociation inhibitor activity 1/186 17/18639 0.0588235294117647 5.89468690702087 0.156815939314592 0.468450162665884 GO:0030548 acetylcholine receptor regulator activity 1/186 17/18639 0.0588235294117647 5.89468690702087 0.156815939314592 0.468450162665884 GO:0038191 neuropilin binding 1/186 17/18639 0.0588235294117647 5.89468690702087 0.156815939314592 0.468450162665884 GO:0051787 misfolded protein binding 1/186 17/18639 0.0588235294117647 5.89468690702087 0.156815939314592 0.468450162665884 GO:0004713 protein tyrosine kinase activity 3/186 140/18639 0.0214285714285714 2.14735023041475 0.164499502293819 0.476065241635167 GO:0043539 protein serine/threonine kinase activator activity 2/186 73/18639 0.0273972602739726 2.7454706142289 0.165080734727469 0.476065241635167 GO:0031690 adrenergic receptor binding 1/186 18/18639 0.0555555555555556 5.56720430107527 0.165237818558899 0.476065241635167 GO:0070064 proline-rich region binding 1/186 18/18639 0.0555555555555556 5.56720430107527 0.165237818558899 0.476065241635167 GO:0099602 neurotransmitter receptor regulator activity 1/186 18/18639 0.0555555555555556 5.56720430107527 0.165237818558899 0.476065241635167 GO:0020037 heme binding 3/186 142/18639 0.0211267605633803 2.11710586097229 0.169360962926548 0.476065241635167 GO:0044183 protein folding chaperone 2/186 75/18639 0.0266666666666667 2.67225806451613 0.172162845651588 0.476065241635167 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 1/186 19/18639 0.0526315789473684 5.2741935483871 0.173576026267833 0.476065241635167 GO:0005346 purine ribonucleotide transmembrane transporter activity 1/186 19/18639 0.0526315789473684 5.2741935483871 0.173576026267833 0.476065241635167 GO:0016918 retinal binding 1/186 19/18639 0.0526315789473684 5.2741935483871 0.173576026267833 0.476065241635167 GO:0030506 ankyrin binding 1/186 19/18639 0.0526315789473684 5.2741935483871 0.173576026267833 0.476065241635167 GO:0042834 peptidoglycan binding 1/186 19/18639 0.0526315789473684 5.2741935483871 0.173576026267833 0.476065241635167 GO:0050145 nucleoside monophosphate kinase activity 1/186 19/18639 0.0526315789473684 5.2741935483871 0.173576026267833 0.476065241635167 GO:0070003 threonine-type peptidase activity 1/186 19/18639 0.0526315789473684 5.2741935483871 0.173576026267833 0.476065241635167 GO:0001972 retinoic acid binding 1/186 20/18639 0.05 5.01048387096774 0.181831389270742 0.48730812324559 GO:0010851 cyclase regulator activity 1/186 20/18639 0.05 5.01048387096774 0.181831389270742 0.48730812324559 GO:0016004 phospholipase activator activity 1/186 20/18639 0.05 5.01048387096774 0.181831389270742 0.48730812324559 GO:0042288 MHC class I protein binding 1/186 20/18639 0.05 5.01048387096774 0.181831389270742 0.48730812324559 GO:0019199 transmembrane receptor protein kinase activity 2/186 78/18639 0.0256410256410256 2.56947890818859 0.182876821232172 0.487325165669822 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 1/186 21/18639 0.0476190476190476 4.77188940092166 0.190004726270347 0.489612799198258 GO:0009931 calcium-dependent protein serine/threonine kinase activity 1/186 21/18639 0.0476190476190476 4.77188940092166 0.190004726270347 0.489612799198258 GO:0048306 calcium-dependent protein binding 2/186 80/18639 0.025 2.50524193548387 0.190073199086736 0.489612799198258 GO:0030971 receptor tyrosine kinase binding 2/186 81/18639 0.0246913580246914 2.47431302270012 0.193685816455835 0.489612799198258 GO:0046906 tetrapyrrole binding 3/186 152/18639 0.0197368421052632 1.97782258064516 0.194257345615803 0.489612799198258 GO:0000287 magnesium ion binding 4/186 230/18639 0.0173913043478261 1.74277699859748 0.198045115442029 0.489612799198258 GO:0005506 iron ion binding 3/186 154/18639 0.0194805194805195 1.95213657310431 0.199343247411344 0.489612799198258 GO:0051117 ATPase binding 2/186 84/18639 0.0238095238095238 2.38594470046083 0.204574892880857 0.489612799198258 GO:0000295 adenine nucleotide transmembrane transporter activity 1/186 23/18639 0.0434782608695652 4.35694249649369 0.20610855691323 0.489612799198258 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 1/186 23/18639 0.0434782608695652 4.35694249649369 0.20610855691323 0.489612799198258 GO:0017134 fibroblast growth factor binding 1/186 23/18639 0.0434782608695652 4.35694249649369 0.20610855691323 0.489612799198258 GO:0031681 G-protein beta-subunit binding 1/186 23/18639 0.0434782608695652 4.35694249649369 0.20610855691323 0.489612799198258 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 1/186 23/18639 0.0434782608695652 4.35694249649369 0.20610855691323 0.489612799198258 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 1/186 23/18639 0.0434782608695652 4.35694249649369 0.20610855691323 0.489612799198258 GO:0051020 GTPase binding 5/186 315/18639 0.0158730158730159 1.59062980030722 0.207315706405999 0.489612799198258 GO:0019001 guanyl nucleotide binding 6/186 400/18639 0.015 1.50314516129032 0.211028727852359 0.489612799198258 GO:0032561 guanyl ribonucleotide binding 6/186 400/18639 0.015 1.50314516129032 0.211028727852359 0.489612799198258 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 1/186 24/18639 0.0416666666666667 4.17540322580645 0.214040648039903 0.489612799198258 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 1/186 24/18639 0.0416666666666667 4.17540322580645 0.214040648039903 0.489612799198258 GO:0005540 hyaluronic acid binding 1/186 24/18639 0.0416666666666667 4.17540322580645 0.214040648039903 0.489612799198258 GO:0015149 hexose transmembrane transporter activity 1/186 24/18639 0.0416666666666667 4.17540322580645 0.214040648039903 0.489612799198258 GO:0030215 semaphorin receptor binding 1/186 24/18639 0.0416666666666667 4.17540322580645 0.214040648039903 0.489612799198258 GO:0030552 cAMP binding 1/186 24/18639 0.0416666666666667 4.17540322580645 0.214040648039903 0.489612799198258 GO:0055056 D-glucose transmembrane transporter activity 1/186 24/18639 0.0416666666666667 4.17540322580645 0.214040648039903 0.489612799198258 GO:0060229 lipase activator activity 1/186 24/18639 0.0416666666666667 4.17540322580645 0.214040648039903 0.489612799198258 GO:0008083 growth factor activity 3/186 162/18639 0.0185185185185185 1.85573476702509 0.219990107278009 0.489612799198258 GO:0003707 nuclear steroid receptor activity 1/186 25/18639 0.04 4.00838709677419 0.221893908285112 0.489612799198258 GO:0016895 DNA exonuclease activity, producing 5'-phosphomonoesters 1/186 25/18639 0.04 4.00838709677419 0.221893908285112 0.489612799198258 GO:0019706 protein-cysteine S-palmitoyltransferase activity 1/186 25/18639 0.04 4.00838709677419 0.221893908285112 0.489612799198258 GO:0019707 protein-cysteine S-acyltransferase activity 1/186 25/18639 0.04 4.00838709677419 0.221893908285112 0.489612799198258 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 1/186 25/18639 0.04 4.00838709677419 0.221893908285112 0.489612799198258 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 2/186 89/18639 0.0224719101123595 2.25190286335629 0.222863237754371 0.489612799198258 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 2/186 89/18639 0.0224719101123595 2.25190286335629 0.222863237754371 0.489612799198258 GO:0140793 histone H2AXY142 phosphatase activity 2/186 90/18639 0.0222222222222222 2.22688172043011 0.226537468448772 0.489612799198258 GO:0004112 cyclic-nucleotide phosphodiesterase activity 1/186 26/18639 0.0384615384615385 3.85421836228288 0.229669116894705 0.489612799198258 GO:0004529 DNA exonuclease activity 1/186 26/18639 0.0384615384615385 3.85421836228288 0.229669116894705 0.489612799198258 GO:0005160 transforming growth factor beta receptor binding 1/186 26/18639 0.0384615384615385 3.85421836228288 0.229669116894705 0.489612799198258 GO:0015145 monosaccharide transmembrane transporter activity 1/186 26/18639 0.0384615384615385 3.85421836228288 0.229669116894705 0.489612799198258 GO:0015216 purine nucleotide transmembrane transporter activity 1/186 26/18639 0.0384615384615385 3.85421836228288 0.229669116894705 0.489612799198258 GO:0030247 polysaccharide binding 1/186 26/18639 0.0384615384615385 3.85421836228288 0.229669116894705 0.489612799198258 GO:0030507 spectrin binding 1/186 26/18639 0.0384615384615385 3.85421836228288 0.229669116894705 0.489612799198258 GO:0043548 phosphatidylinositol 3-kinase binding 1/186 26/18639 0.0384615384615385 3.85421836228288 0.229669116894705 0.489612799198258 GO:0050681 nuclear androgen receptor binding 1/186 26/18639 0.0384615384615385 3.85421836228288 0.229669116894705 0.489612799198258 GO:0050750 low-density lipoprotein particle receptor binding 1/186 26/18639 0.0384615384615385 3.85421836228288 0.229669116894705 0.489612799198258 GO:0033218 amide binding 4/186 247/18639 0.0161943319838057 1.62282878411911 0.233579921686316 0.491921605048678 GO:0035402 histone H3T11 kinase activity 4/186 247/18639 0.0161943319838057 1.62282878411911 0.233579921686316 0.491921605048678 GO:0043178 alcohol binding 2/186 92/18639 0.0217391304347826 2.17847124824684 0.233898758903742 0.491921605048678 GO:0004364 glutathione transferase activity 1/186 27/18639 0.037037037037037 3.71146953405018 0.23736704545311 0.494778419188927 GO:0005044 scavenger receptor activity 1/186 27/18639 0.037037037037037 3.71146953405018 0.23736704545311 0.494778419188927 GO:0042562 hormone binding 2/186 94/18639 0.0212765957446809 2.13212079615649 0.241274187971626 0.497400808581907 GO:0045499 chemorepellent activity 1/186 28/18639 0.0357142857142857 3.57891705069124 0.244988457958253 0.497400808581907 GO:0051019 mitogen-activated protein kinase binding 1/186 28/18639 0.0357142857142857 3.57891705069124 0.244988457958253 0.497400808581907 GO:0051119 sugar transmembrane transporter activity 1/186 28/18639 0.0357142857142857 3.57891705069124 0.244988457958253 0.497400808581907 GO:0051393 alpha-actinin binding 1/186 28/18639 0.0357142857142857 3.57891705069124 0.244988457958253 0.497400808581907 GO:0097718 disordered domain specific binding 1/186 28/18639 0.0357142857142857 3.57891705069124 0.244988457958253 0.497400808581907 GO:0003785 actin monomer binding 1/186 29/18639 0.0344827586206897 3.45550611790879 0.25253411089575 0.503993608553647 GO:0016417 S-acyltransferase activity 1/186 29/18639 0.0344827586206897 3.45550611790879 0.25253411089575 0.503993608553647 GO:0043236 laminin binding 1/186 29/18639 0.0344827586206897 3.45550611790879 0.25253411089575 0.503993608553647 GO:0051861 glycolipid binding 1/186 29/18639 0.0344827586206897 3.45550611790879 0.25253411089575 0.503993608553647 GO:0004725 protein tyrosine phosphatase activity 2/186 98/18639 0.0204081632653061 2.04509545753785 0.256053817374761 0.505984353956448 GO:0001965 G-protein alpha-subunit binding 1/186 30/18639 0.0333333333333333 3.34032258064516 0.260004753312375 0.505984353956448 GO:0015215 nucleotide transmembrane transporter activity 1/186 30/18639 0.0333333333333333 3.34032258064516 0.260004753312375 0.505984353956448 GO:0016769 transferase activity, transferring nitrogenous groups 1/186 30/18639 0.0333333333333333 3.34032258064516 0.260004753312375 0.505984353956448 GO:0031210 phosphatidylcholine binding 1/186 30/18639 0.0333333333333333 3.34032258064516 0.260004753312375 0.505984353956448 GO:0051721 protein phosphatase 2A binding 1/186 30/18639 0.0333333333333333 3.34032258064516 0.260004753312375 0.505984353956448 GO:0043130 ubiquitin binding 2/186 100/18639 0.02 2.0041935483871 0.26345151612779 0.510573392826171 GO:0005164 tumor necrosis factor receptor binding 1/186 31/18639 0.032258064516129 3.23257023933403 0.267401126888811 0.513980034880543 GO:0070325 lipoprotein particle receptor binding 1/186 31/18639 0.032258064516129 3.23257023933403 0.267401126888811 0.513980034880543 GO:0030515 snoRNA binding 1/186 32/18639 0.03125 3.13155241935484 0.274723966011698 0.525900163508109 GO:0016757 glycosyltransferase activity 4/186 267/18639 0.0149812734082397 1.50126857557086 0.277150053527064 0.528246442836849 GO:0003779 actin binding 6/186 443/18639 0.0135440180586907 1.35724168062332 0.281877002726369 0.528246442836849 GO:0030296 protein tyrosine kinase activator activity 1/186 33/18639 0.0303030303030303 3.0366568914956 0.281973997844977 0.528246442836849 GO:0140416 transcription regulator inhibitor activity 1/186 33/18639 0.0303030303030303 3.0366568914956 0.281973997844977 0.528246442836849 GO:0140996 histone H3 kinase activity 5/186 357/18639 0.0140056022408964 1.40349688262402 0.285153780962182 0.528246442836849 GO:0005096 GTPase activator activity 4/186 271/18639 0.014760147601476 1.47910962980598 0.286030729823211 0.528246442836849 GO:0008376 acetylgalactosaminyltransferase activity 1/186 34/18639 0.0294117647058824 2.94734345351044 0.289151942400542 0.528246442836849 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 1/186 34/18639 0.0294117647058824 2.94734345351044 0.289151942400542 0.528246442836849 GO:0019825 oxygen binding 1/186 34/18639 0.0294117647058824 2.94734345351044 0.289151942400542 0.528246442836849 GO:0090482 vitamin transmembrane transporter activity 1/186 34/18639 0.0294117647058824 2.94734345351044 0.289151942400542 0.528246442836849 GO:0019888 protein phosphatase regulator activity 2/186 107/18639 0.0186915887850467 1.87307808260476 0.289333291266339 0.528246442836849 GO:0140597 protein carrier chaperone 3/186 188/18639 0.0159574468085106 1.59909059711736 0.289465534774137 0.528246442836849 GO:0035173 histone kinase activity 5/186 360/18639 0.0138888888888889 1.39180107526882 0.290936973553922 0.52887380076275 GO:0005496 steroid binding 2/186 108/18639 0.0185185185185185 1.85573476702509 0.293024699230599 0.530612293201355 GO:0000175 3'-5'-RNA exonuclease activity 1/186 35/18639 0.0285714285714286 2.863133640553 0.296258512608201 0.531140012969637 GO:0005154 epidermal growth factor receptor binding 1/186 35/18639 0.0285714285714286 2.863133640553 0.296258512608201 0.531140012969637 GO:0004620 phospholipase activity 2/186 109/18639 0.018348623853211 1.83870967741935 0.296713610656812 0.531140012969637 GO:0004190 aspartic-type endopeptidase activity 1/186 36/18639 0.0277777777777778 2.78360215053763 0.303294414384963 0.536773888100179 GO:0004869 cysteine-type endopeptidase inhibitor activity 1/186 36/18639 0.0277777777777778 2.78360215053763 0.303294414384963 0.536773888100179 GO:0016409 palmitoyltransferase activity 1/186 36/18639 0.0277777777777778 2.78360215053763 0.303294414384963 0.536773888100179 GO:0030551 cyclic nucleotide binding 1/186 37/18639 0.027027027027027 2.70836965998256 0.310260346703642 0.542955606731374 GO:0042805 actinin binding 1/186 37/18639 0.027027027027027 2.70836965998256 0.310260346703642 0.542955606731374 GO:0070001 aspartic-type peptidase activity 1/186 37/18639 0.027027027027027 2.70836965998256 0.310260346703642 0.542955606731374 GO:0031267 small GTPase binding 4/186 283/18639 0.0141342756183746 1.41639120027357 0.312900841341936 0.545540872079435 GO:0005109 frizzled binding 1/186 38/18639 0.0263157894736842 2.63709677419355 0.317157001660804 0.548880567449879 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 1/186 38/18639 0.0263157894736842 2.63709677419355 0.317157001660804 0.548880567449879 GO:0016776 phosphotransferase activity, phosphate group as acceptor 1/186 39/18639 0.0256410256410256 2.56947890818859 0.323985064544042 0.553998233280156 GO:0005525 GTP binding 5/186 378/18639 0.0132275132275132 1.32552483358935 0.326027473511109 0.553998233280156 GO:0004532 RNA exonuclease activity 1/186 40/18639 0.025 2.50524193548387 0.3307452138986 0.553998233280156 GO:0015036 disulfide oxidoreductase activity 1/186 40/18639 0.025 2.50524193548387 0.3307452138986 0.553998233280156 GO:0015144 carbohydrate transmembrane transporter activity 1/186 40/18639 0.025 2.50524193548387 0.3307452138986 0.553998233280156 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 1/186 40/18639 0.025 2.50524193548387 0.3307452138986 0.553998233280156 GO:0050997 quaternary ammonium group binding 1/186 40/18639 0.025 2.50524193548387 0.3307452138986 0.553998233280156 GO:0061791 GTPase motor activity 1/186 40/18639 0.025 2.50524193548387 0.3307452138986 0.553998233280156 GO:1990606 membrane scission GTPase motor activity 1/186 40/18639 0.025 2.50524193548387 0.3307452138986 0.553998233280156 GO:0032182 ubiquitin-like protein binding 2/186 120/18639 0.0166666666666667 1.67016129032258 0.337040907145203 0.559217240379105 GO:0017080 sodium channel regulator activity 1/186 41/18639 0.024390243902439 2.4441384736428 0.337438121593362 0.559217240379105 GO:0042287 MHC protein binding 1/186 41/18639 0.024390243902439 2.4441384736428 0.337438121593362 0.559217240379105 GO:0004540 RNA nuclease activity 2/186 121/18639 0.0165289256198347 1.65635830445215 0.34067697379839 0.560622809513842 GO:0051082 unfolded protein binding 2/186 121/18639 0.0165289256198347 1.65635830445215 0.34067697379839 0.560622809513842 GO:0008307 structural constituent of muscle 1/186 42/18639 0.0238095238095238 2.38594470046083 0.344064452886169 0.561670715055654 GO:0008528 G protein-coupled peptide receptor activity 2/186 122/18639 0.0163934426229508 1.6427815970386 0.344306910962394 0.561670715055654 GO:0048156 tau protein binding 1/186 43/18639 0.0232558139534884 2.3304576144036 0.350624866488534 0.561670715055654 GO:0001046 core promoter sequence-specific DNA binding 1/186 44/18639 0.0227272727272727 2.2774926686217 0.3571200146297 0.561670715055654 GO:0001223 transcription coactivator binding 1/186 44/18639 0.0227272727272727 2.2774926686217 0.3571200146297 0.561670715055654 GO:0019205 nucleobase-containing compound kinase activity 1/186 44/18639 0.0227272727272727 2.2774926686217 0.3571200146297 0.561670715055654 GO:0043014 alpha-tubulin binding 1/186 44/18639 0.0227272727272727 2.2774926686217 0.3571200146297 0.561670715055654 GO:0140297 DNA-binding transcription factor binding 6/186 488/18639 0.0122950819672131 1.23208619777895 0.360748584813141 0.561670715055654 GO:0019783 ubiquitin-like protein peptidase activity 2/186 127/18639 0.015748031496063 1.57810515621031 0.362356469257798 0.561670715055654 GO:0001653 peptide receptor activity 2/186 128/18639 0.015625 1.56577620967742 0.365944791172759 0.561670715055654 GO:0035591 signaling adaptor activity 2/186 129/18639 0.0155038759689922 1.5536384096024 0.369525418692444 0.561670715055654 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 1/186 46/18639 0.0217391304347826 2.17847124824684 0.36991709141415 0.561670715055654 GO:0030291 protein serine/threonine kinase inhibitor activity 1/186 46/18639 0.0217391304347826 2.17847124824684 0.36991709141415 0.561670715055654 GO:0016298 lipase activity 2/186 130/18639 0.0153846153846154 1.54168734491315 0.373098148302461 0.561670715055654 GO:0043495 protein-membrane adaptor activity 1/186 47/18639 0.0212765957446809 2.13212079615649 0.376220292672525 0.561670715055654 GO:0005179 hormone activity 2/186 132/18639 0.0151515151515152 1.5183284457478 0.38021912356448 0.561670715055654 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 1/186 48/18639 0.0208333333333333 2.08770161290323 0.382460773823714 0.561670715055654 GO:0016879 ligase activity, forming carbon-nitrogen bonds 1/186 48/18639 0.0208333333333333 2.08770161290323 0.382460773823714 0.561670715055654 GO:0038187 pattern recognition receptor activity 1/186 48/18639 0.0208333333333333 2.08770161290323 0.382460773823714 0.561670715055654 GO:0140693 molecular condensate scaffold activity 1/186 48/18639 0.0208333333333333 2.08770161290323 0.382460773823714 0.561670715055654 GO:0005004 GPI-linked ephrin receptor activity 1/186 49/18639 0.0204081632653061 2.04509545753785 0.388639155625058 0.561670715055654 GO:0005008 hepatocyte growth factor receptor activity 1/186 49/18639 0.0204081632653061 2.04509545753785 0.388639155625058 0.561670715055654 GO:0005009 insulin receptor activity 1/186 49/18639 0.0204081632653061 2.04509545753785 0.388639155625058 0.561670715055654 GO:0005011 macrophage colony-stimulating factor receptor activity 1/186 49/18639 0.0204081632653061 2.04509545753785 0.388639155625058 0.561670715055654 GO:0005018 platelet-derived growth factor alpha-receptor activity 1/186 49/18639 0.0204081632653061 2.04509545753785 0.388639155625058 0.561670715055654 GO:0005020 stem cell factor receptor activity 1/186 49/18639 0.0204081632653061 2.04509545753785 0.388639155625058 0.561670715055654 GO:0008288 boss receptor activity 1/186 49/18639 0.0204081632653061 2.04509545753785 0.388639155625058 0.561670715055654 GO:0035254 glutamate receptor binding 1/186 49/18639 0.0204081632653061 2.04509545753785 0.388639155625058 0.561670715055654 GO:0036332 placental growth factor receptor activity 1/186 49/18639 0.0204081632653061 2.04509545753785 0.388639155625058 0.561670715055654 GO:0038062 protein tyrosine kinase collagen receptor activity 1/186 49/18639 0.0204081632653061 2.04509545753785 0.388639155625058 0.561670715055654 GO:0060175 brain-derived neurotrophic factor receptor activity 1/186 49/18639 0.0204081632653061 2.04509545753785 0.388639155625058 0.561670715055654 GO:0140789 histone phosphatase activity 2/186 136/18639 0.0147058823529412 1.47367172675522 0.394357866133366 0.561670715055654 GO:0005007 fibroblast growth factor receptor activity 1/186 50/18639 0.02 2.0041935483871 0.394756052723161 0.561670715055654 GO:0005017 platelet-derived growth factor receptor activity 1/186 50/18639 0.02 2.0041935483871 0.394756052723161 0.561670715055654 GO:0005019 platelet-derived growth factor beta-receptor activity 1/186 50/18639 0.02 2.0041935483871 0.394756052723161 0.561670715055654 GO:0015605 organophosphate ester transmembrane transporter activity 1/186 50/18639 0.02 2.0041935483871 0.394756052723161 0.561670715055654 GO:0032813 tumor necrosis factor receptor superfamily binding 1/186 50/18639 0.02 2.0041935483871 0.394756052723161 0.561670715055654 GO:0005010 insulin-like growth factor receptor activity 1/186 51/18639 0.0196078431372549 1.96489563567362 0.40081207371372 0.561670715055654 GO:0005021 vascular endothelial growth factor receptor activity 1/186 51/18639 0.0196078431372549 1.96489563567362 0.40081207371372 0.561670715055654 GO:0005030 neurotrophin receptor activity 1/186 51/18639 0.0196078431372549 1.96489563567362 0.40081207371372 0.561670715055654 GO:0030159 signaling receptor complex adaptor activity 1/186 52/18639 0.0192307692307692 1.92710918114144 0.406807821200768 0.561670715055654 GO:0005003 ephrin receptor activity 1/186 53/18639 0.0188679245283019 1.89074863055386 0.412743891855347 0.561670715055654 GO:0005005 transmembrane-ephrin receptor activity 1/186 53/18639 0.0188679245283019 1.89074863055386 0.412743891855347 0.561670715055654 GO:0005246 calcium channel regulator activity 1/186 53/18639 0.0188679245283019 1.89074863055386 0.412743891855347 0.561670715055654 GO:0016860 intramolecular oxidoreductase activity 1/186 53/18639 0.0188679245283019 1.89074863055386 0.412743891855347 0.561670715055654 GO:0017046 peptide hormone binding 1/186 53/18639 0.0188679245283019 1.89074863055386 0.412743891855347 0.561670715055654 GO:0038064 collagen receptor activity 1/186 53/18639 0.0188679245283019 1.89074863055386 0.412743891855347 0.561670715055654 GO:1901505 carbohydrate derivative transmembrane transporter activity 1/186 53/18639 0.0188679245283019 1.89074863055386 0.412743891855347 0.561670715055654 GO:0015485 cholesterol binding 1/186 54/18639 0.0185185185185185 1.85573476702509 0.418620876473602 0.561670715055654 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 1/186 54/18639 0.0185185185185185 1.85573476702509 0.418620876473602 0.561670715055654 GO:0017069 snRNA binding 1/186 54/18639 0.0185185185185185 1.85573476702509 0.418620876473602 0.561670715055654 GO:0050661 NADP binding 1/186 54/18639 0.0185185185185185 1.85573476702509 0.418620876473602 0.561670715055654 GO:0051287 NAD binding 1/186 54/18639 0.0185185185185185 1.85573476702509 0.418620876473602 0.561670715055654 GO:0019903 protein phosphatase binding 2/186 144/18639 0.0138888888888889 1.39180107526882 0.422184044684804 0.561670715055654 GO:0045296 cadherin binding 4/186 334/18639 0.0119760479041916 1.20011589723778 0.42795407684506 0.561670715055654 GO:0170055 lipid transmembrane transporter activity 1/186 56/18639 0.0178571428571429 1.78945852534562 0.430199921755887 0.561670715055654 GO:0015932 nucleobase-containing compound transmembrane transporter activity 1/186 57/18639 0.0175438596491228 1.75806451612903 0.435903135152723 0.561670715055654 GO:0016504 peptidase activator activity 1/186 57/18639 0.0175438596491228 1.75806451612903 0.435903135152723 0.561670715055654 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 3/186 243/18639 0.0123456790123457 1.23715651135006 0.438052101855751 0.561670715055654 GO:0008408 3'-5' exonuclease activity 1/186 58/18639 0.0172413793103448 1.72775305895439 0.441549568091136 0.561670715055654 GO:0004676 3-phosphoinositide-dependent protein kinase activity 3/186 245/18639 0.0122448979591837 1.22705727452271 0.443297059685925 0.561670715055654 GO:0004711 ribosomal protein S6 kinase activity 3/186 245/18639 0.0122448979591837 1.22705727452271 0.443297059685925 0.561670715055654 GO:0035175 histone H3S10 kinase activity 3/186 245/18639 0.0122448979591837 1.22705727452271 0.443297059685925 0.561670715055654 GO:0035979 histone H2AXS139 kinase activity 3/186 245/18639 0.0122448979591837 1.22705727452271 0.443297059685925 0.561670715055654 GO:0044022 histone H3S28 kinase activity 3/186 245/18639 0.0122448979591837 1.22705727452271 0.443297059685925 0.561670715055654 GO:0044023 histone H4S1 kinase activity 3/186 245/18639 0.0122448979591837 1.22705727452271 0.443297059685925 0.561670715055654 GO:0044024 histone H2AS1 kinase activity 3/186 245/18639 0.0122448979591837 1.22705727452271 0.443297059685925 0.561670715055654 GO:0044025 histone H2BS14 kinase activity 3/186 245/18639 0.0122448979591837 1.22705727452271 0.443297059685925 0.561670715055654 GO:0072354 histone H3T3 kinase activity 3/186 245/18639 0.0122448979591837 1.22705727452271 0.443297059685925 0.561670715055654 GO:0072371 histone H2AS121 kinase activity 3/186 245/18639 0.0122448979591837 1.22705727452271 0.443297059685925 0.561670715055654 GO:0072518 Rho-dependent protein serine/threonine kinase activity 3/186 245/18639 0.0122448979591837 1.22705727452271 0.443297059685925 0.561670715055654 GO:0140823 histone H2BS36 kinase activity 3/186 245/18639 0.0122448979591837 1.22705727452271 0.443297059685925 0.561670715055654 GO:0140855 histone H3S57 kinase activity 3/186 245/18639 0.0122448979591837 1.22705727452271 0.443297059685925 0.561670715055654 GO:0140995 histone H2A kinase activity 3/186 245/18639 0.0122448979591837 1.22705727452271 0.443297059685925 0.561670715055654 GO:0140997 histone H4 kinase activity 3/186 245/18639 0.0122448979591837 1.22705727452271 0.443297059685925 0.561670715055654 GO:0140998 histone H2B kinase activity 3/186 245/18639 0.0122448979591837 1.22705727452271 0.443297059685925 0.561670715055654 GO:1990244 histone H2AT120 kinase activity 3/186 245/18639 0.0122448979591837 1.22705727452271 0.443297059685925 0.561670715055654 GO:0004677 DNA-dependent protein kinase activity 3/186 246/18639 0.0121951219512195 1.2220692368214 0.445912503612044 0.561670715055654 GO:0140857 histone H3T45 kinase activity 3/186 246/18639 0.0121951219512195 1.2220692368214 0.445912503612044 0.561670715055654 GO:0000510 H3-H4 histone complex chaperone activity 2/186 151/18639 0.0132450331125828 1.32728049562059 0.445988401403358 0.561670715055654 GO:0140584 chromatin extrusion motor activity 2/186 151/18639 0.0132450331125828 1.32728049562059 0.445988401403358 0.561670715055654 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 2/186 151/18639 0.0132450331125828 1.32728049562059 0.445988401403358 0.561670715055654 GO:0140849 ATP-dependent H2AZ histone chaperone activity 2/186 151/18639 0.0132450331125828 1.32728049562059 0.445988401403358 0.561670715055654 GO:0004879 nuclear receptor activity 1/186 59/18639 0.0169491525423729 1.69846910880262 0.44713978284465 0.561670715055654 GO:0031593 polyubiquitin modification-dependent protein binding 1/186 59/18639 0.0169491525423729 1.69846910880262 0.44713978284465 0.561670715055654 GO:0035403 histone H3T6 kinase activity 3/186 247/18639 0.0121457489878543 1.21712158808933 0.448523150111131 0.561670715055654 GO:0042393 histone binding 3/186 247/18639 0.0121457489878543 1.21712158808933 0.448523150111131 0.561670715055654 GO:0015616 DNA translocase activity 2/186 152/18639 0.0131578947368421 1.31854838709677 0.449344815480525 0.561670715055654 GO:0140674 ATP-dependent histone chaperone activity 2/186 152/18639 0.0131578947368421 1.31854838709677 0.449344815480525 0.561670715055654 GO:0004679 AMP-activated protein kinase activity 3/186 248/18639 0.0120967741935484 1.21221383975026 0.451128920086356 0.561670715055654 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 1/186 60/18639 0.0166666666666667 1.67016129032258 0.452674336148788 0.561670715055654 GO:0098531 ligand-modulated transcription factor activity 1/186 60/18639 0.0166666666666667 1.67016129032258 0.452674336148788 0.561670715055654 GO:0061775 cohesin loader activity 2/186 153/18639 0.0130718954248366 1.30993042378242 0.452689830044856 0.561670715055654 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 1/186 61/18639 0.0163934426229508 1.6427815970386 0.458153779255325 0.566950191215692 GO:0140658 ATP-dependent chromatin remodeler activity 2/186 158/18639 0.0126582278481013 1.26847692935892 0.469240264303479 0.579141273574557 GO:0141003 histone H2AX kinase activity 4/186 354/18639 0.0112994350282486 1.13231273920175 0.472037905459948 0.581065033230225 GO:0004536 DNA nuclease activity 1/186 64/18639 0.015625 1.56577620967742 0.474266878775281 0.582280539648185 GO:0003689 DNA clamp loader activity 2/186 160/18639 0.0125 1.25262096774194 0.475777128028406 0.582609590196664 GO:0019843 rRNA binding 1/186 65/18639 0.0153846153846154 1.54168734491315 0.479531285803426 0.585677533963038 GO:0106310 protein serine kinase activity 4/186 361/18639 0.0110803324099723 1.11035653650255 0.487181727327876 0.59347592238123 GO:0140713 histone chaperone activity 2/186 164/18639 0.0121951219512195 1.2220692368214 0.488704165975036 0.593707119778167 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 1/186 67/18639 0.0149253731343284 1.49566682715455 0.48990331632015 0.593707119778167 GO:0032934 sterol binding 1/186 68/18639 0.0147058823529412 1.47367172675522 0.495011973608781 0.596813921908788 GO:1990841 promoter-specific chromatin binding 1/186 68/18639 0.0147058823529412 1.47367172675522 0.495011973608781 0.596813921908788 GO:0002039 p53 binding 1/186 69/18639 0.0144927536231884 1.4523141654979 0.500069739636931 0.60136591766595 GO:0008201 heparin binding 2/186 172/18639 0.0116279069767442 1.1652288072018 0.513954774881034 0.616482837389271 GO:0004721 phosphoprotein phosphatase activity 2/186 175/18639 0.0114285714285714 1.1452534562212 0.523211075997798 0.625984680211651 GO:0043021 ribonucleoprotein complex binding 2/186 177/18639 0.0112994350282486 1.13231273920175 0.529316346647551 0.630144962724461 GO:0003725 double-stranded RNA binding 1/186 75/18639 0.0133333333333333 1.33612903225806 0.529375512395389 0.630144962724461 GO:0030246 carbohydrate binding 3/186 280/18639 0.0107142857142857 1.07367511520737 0.53152467244636 0.631101446524919 GO:0017022 myosin binding 1/186 76/18639 0.0131578947368421 1.31854838709677 0.534090883796728 0.632547031567337 GO:0003724 RNA helicase activity 1/186 77/18639 0.012987012987013 1.30142438206954 0.538759261516591 0.636468749751338 GO:0008186 ATP-dependent activity, acting on RNA 1/186 79/18639 0.0126582278481013 1.26847692935892 0.547956894660787 0.642479458989773 GO:0015370 solute:sodium symporter activity 1/186 79/18639 0.0126582278481013 1.26847692935892 0.547956894660787 0.642479458989773 GO:0033293 monocarboxylic acid binding 1/186 79/18639 0.0126582278481013 1.26847692935892 0.547956894660787 0.642479458989773 GO:0003712 transcription coregulator activity 5/186 495/18639 0.0101010101010101 1.01221896383187 0.55192535766366 0.645518685147772 GO:0001618 virus receptor activity 1/186 81/18639 0.0123456790123457 1.23715651135006 0.556972083667067 0.649800764278245 GO:0140272 exogenous protein binding 1/186 82/18639 0.0121951219512195 1.2220692368214 0.561412389327048 0.653355857554306 GO:0019902 phosphatase binding 2/186 190/18639 0.0105263157894737 1.05483870967742 0.567698838355098 0.659036522743913 GO:0004527 exonuclease activity 1/186 84/18639 0.0119047619047619 1.19297235023041 0.570160639589967 0.660260098685665 GO:0016758 hexosyltransferase activity 2/186 197/18639 0.0101522842639594 1.01735713116096 0.587418165494463 0.678569260140155 GO:0003727 single-stranded RNA binding 1/186 89/18639 0.0112359550561798 1.12595143167814 0.591279342517226 0.681351379952283 GO:0005516 calmodulin binding 2/186 207/18639 0.00966183574879227 0.968209443665264 0.614426552389284 0.705522344681141 GO:0004867 serine-type endopeptidase inhibitor activity 1/186 95/18639 0.0105263157894737 1.05483870967742 0.615263622547093 0.705522344681141 GO:0004518 nuclease activity 2/186 209/18639 0.00956937799043062 0.958944281524927 0.619664132934662 0.708835313039894 GO:0008094 ATP-dependent activity, acting on DNA 2/186 210/18639 0.00952380952380952 0.954377880184332 0.622262450988378 0.710075643585278 GO:0004674 protein serine/threonine kinase activity 4/186 433/18639 0.0092378752886836 0.925724502719213 0.630550451698364 0.717786800598381 GO:0140097 catalytic activity, acting on DNA 3/186 336/18639 0.00892857142857143 0.894729262672811 0.654846953284553 0.742760873734524 GO:0004497 monooxygenase activity 1/186 106/18639 0.00943396226415094 0.945374315276932 0.655656720098279 0.742760873734524 GO:0004843 cysteine-type deubiquitinase activity 1/186 108/18639 0.00925925925925926 0.927867383512545 0.662533983766576 0.748743225027769 GO:0005200 structural constituent of cytoskeleton 1/186 112/18639 0.00892857142857143 0.894729262672811 0.675881321930343 0.760163884856909 GO:0043022 ribosome binding 1/186 112/18639 0.00892857142857143 0.894729262672811 0.675881321930343 0.760163884856909 GO:0017124 SH3 domain binding 1/186 115/18639 0.00869565217391304 0.871388499298738 0.685546036017251 0.763708054375512 GO:0035401 histone H3Y41 kinase activity 1/186 115/18639 0.00869565217391304 0.871388499298738 0.685546036017251 0.763708054375512 GO:0101005 deubiquitinase activity 1/186 115/18639 0.00869565217391304 0.871388499298738 0.685546036017251 0.763708054375512 GO:0140801 histone H2AXY142 kinase activity 1/186 115/18639 0.00869565217391304 0.871388499298738 0.685546036017251 0.763708054375512 GO:0015294 solute:monoatomic cation symporter activity 1/186 116/18639 0.00862068965517241 0.863876529477197 0.688703477028954 0.765407418783363 GO:0046982 protein heterodimerization activity 3/186 369/18639 0.00813008130081301 0.8147128245476 0.715854933238494 0.793702041817621 GO:0030695 GTPase regulator activity 4/186 489/18639 0.0081799591002045 0.819711062735009 0.722744292918039 0.799203340405336 GO:0060589 nucleoside-triphosphatase regulator activity 4/186 490/18639 0.00816326530612245 0.818038183015142 0.724224775420614 0.799203340405336 GO:0003713 transcription coactivator activity 2/186 256/18639 0.0078125 0.78288810483871 0.727405386129168 0.800828934494318 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 1/186 130/18639 0.00769230769230769 0.770843672456576 0.729734859530734 0.801512058828839 GO:0031072 heat shock protein binding 1/186 131/18639 0.00763358778625954 0.764959369613396 0.732450798594286 0.802615477898878 GO:0015631 tubulin binding 3/186 385/18639 0.00779220779220779 0.780854629241726 0.7423045733251 0.809490349406193 GO:0015297 antiporter activity 1/186 135/18639 0.00740740740740741 0.742293906810036 0.743045764087949 0.809490349406193 GO:0140098 catalytic activity, acting on RNA 3/186 387/18639 0.00775193798449612 0.7768192048012 0.745470235967432 0.809490349406193 GO:0016779 nucleotidyltransferase activity 1/186 136/18639 0.00735294117647059 0.736835863377609 0.745628637406131 0.809490349406193 GO:0016922 nuclear receptor binding 1/186 137/18639 0.0072992700729927 0.731457499411349 0.748185686178895 0.810390500734185 GO:0070851 growth factor receptor binding 1/186 139/18639 0.00719424460431655 0.720932931074495 0.753223334834928 0.813967152160326 GO:0016791 phosphatase activity 2/186 273/18639 0.00732600732600733 0.734136830911024 0.759518924544198 0.818883622094779 GO:1901681 sulfur compound binding 2/186 275/18639 0.00727272727272727 0.728797653958944 0.763074928976198 0.820830600206047 GO:0008194 UDP-glycosyltransferase activity 1/186 145/18639 0.00689655172413793 0.691101223581758 0.76774268411856 0.823961828035708 GO:0015293 symporter activity 1/186 146/18639 0.00684931506849315 0.686367653557225 0.770078569311268 0.82458184704791 GO:0019842 vitamin binding 1/186 150/18639 0.00666666666666667 0.668064516129032 0.779190746805206 0.832438406040185 GO:0015291 secondary active transmembrane transporter activity 2/186 287/18639 0.00696864111498258 0.698325278183657 0.783470921533347 0.835108777725317 GO:0003774 cytoskeletal motor activity 1/186 153/18639 0.0065359477124183 0.654965211891208 0.785788331222886 0.835679653840212 GO:0016887 ATP hydrolysis activity 3/186 417/18639 0.00719424460431655 0.720932931074495 0.789331896413026 0.836447645946964 GO:0004386 helicase activity 1/186 155/18639 0.00645161290322581 0.646514047866805 0.790077413975491 0.836447645946964 GO:0015081 sodium ion transmembrane transporter activity 1/186 164/18639 0.00609756097560976 0.6110346184107 0.808345271871202 0.853860208350436 GO:0016874 ligase activity 1/186 167/18639 0.00598802395209581 0.600057948618891 0.814076040775035 0.857981265446048 GO:0140030 modification-dependent protein binding 1/186 173/18639 0.00578034682080925 0.579246690285288 0.825031227804183 0.867577681255969 GO:0005319 lipid transporter activity 1/186 178/18639 0.00561797752808989 0.562975715839072 0.83366832855404 0.874698984545514 GO:0016853 isomerase activity 1/186 180/18639 0.00555555555555556 0.556720430107527 0.837003214773449 0.876001786144409 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 1/186 181/18639 0.00552486187845304 0.55364462662627 0.838645633217142 0.876001786144409 GO:0015078 proton transmembrane transporter activity 1/186 185/18639 0.00540540540540541 0.541673931996513 0.845052324377671 0.880732311406951 GO:0031406 carboxylic acid binding 1/186 187/18639 0.0053475935828877 0.535880627910988 0.848160138325833 0.882011319012895 GO:0043177 organic acid binding 1/186 189/18639 0.00529100529100529 0.53020993343574 0.851205946713894 0.883220329665522 GO:0005543 phospholipid binding 3/186 497/18639 0.00603621730382294 0.604887388849224 0.876592575457102 0.907538543939038 GO:0051015 actin filament binding 1/186 209/18639 0.00478468899521531 0.479472140762463 0.878512790934591 0.907538543939038 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 1/186 229/18639 0.00436681222707424 0.437596844626004 0.900830198619657 0.928548050884877 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 1/186 268/18639 0.00373134328358209 0.373916706788637 0.933287441823927 0.958487072821752 GO:0008514 organic anion transmembrane transporter activity 1/186 269/18639 0.00371747211895911 0.372526681856338 0.933962883325246 0.958487072821752 GO:0008017 microtubule binding 1/186 276/18639 0.0036231884057971 0.363078541374474 0.938504280356657 0.960217513722118 GO:0001217 DNA-binding transcription repressor activity 1/186 278/18639 0.00359712230215827 0.360466465537248 0.939743792747233 0.960217513722118 GO:0035091 phosphatidylinositol binding 1/186 284/18639 0.00352112676056338 0.352850976828714 0.943315190165825 0.961157900110153 GO:0022804 active transmembrane transporter activity 2/186 457/18639 0.00437636761487965 0.438554386955601 0.944762882624266 0.961157900110153 GO:0061630 ubiquitin protein ligase activity 1/186 353/18639 0.0028328611898017 0.283880106003838 0.97196601040597 0.986692768139393 GO:0061659 ubiquitin-like protein ligase activity 1/186 372/18639 0.00268817204301075 0.269380853277836 0.97691762596499 0.989577465610325 GO:0004842 ubiquitin-protein transferase activity 1/186 449/18639 0.0022271714922049 0.223184136791436 0.989521126891823 0.993539682971044 GO:0046873 metal ion transmembrane transporter activity 1/186 450/18639 0.00222222222222222 0.222688172043011 0.989628277545926 0.993539682971044 GO:0019787 ubiquitin-like protein transferase activity 1/186 479/18639 0.00208768267223382 0.209206007138528 0.992303445935769 0.993539682971044 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 1/186 484/18639 0.00206611570247934 0.207044788056518 0.992689647563396 0.993539682971044 GO:0001216 DNA-binding transcription activator activity 1/186 491/18639 0.00203665987780041 0.204093029367321 0.993198155455361 0.993539682971044 GO:0016755 aminoacyltransferase activity 1/186 496/18639 0.00201612903225806 0.202035639958377 0.993539682971044 0.993539682971044