category subcategory ID Description GeneRatio BgRatio FoldEnrichment geneName zScore Human Diseases Infectious disease: viral hsa05171 Coronavirus disease - COVID-19 11/29 238/9376 14.9429150970733 RPL23A/RPLP2/RPL30/RPS15A/RPSA/RPS24/RPL17/RPS21/RPS15/ISG15/RPS27A 12.1357047038464 Genetic Information Processing Translation hsa03010 Ribosome 10/29 222/9376 14.5635290462877 RPL23A/RPLP2/RPL30/RPS15A/RPSA/RPS24/RPL17/RPS21/RPS15/RPS27A 11.3917973527497 Organismal Systems Immune system hsa04612 Antigen processing and presentation 5/29 82/9376 19.7140454163162 HLA-C/HLA-A/HLA-G/HLA-DRB5/TAPBP 9.48029359140432 Human Diseases Immune disease hsa05330 Allograft rejection 4/29 39/9376 33.1600353669319 HLA-C/HLA-A/HLA-G/HLA-DRB5 11.2096914219613 Human Diseases Endocrine and metabolic disease hsa04940 Type I diabetes mellitus 4/29 44/9376 29.3918495297806 HLA-C/HLA-A/HLA-G/HLA-DRB5 10.5143195926338 Human Diseases Immune disease hsa05332 Graft-versus-host disease 4/29 45/9376 28.7386973180077 HLA-C/HLA-A/HLA-G/HLA-DRB5 10.3890716050488 Human Diseases Infectious disease: viral hsa05168 Herpes simplex virus 1 infection 6/29 180/9376 10.7770114942529 HLA-C/CCL5/HLA-A/HLA-G/HLA-DRB5/TAPBP 7.37719754090858 Human Diseases Immune disease hsa05320 Autoimmune thyroid disease 4/29 54/9376 23.948914431673 HLA-C/HLA-A/HLA-G/HLA-DRB5 9.42004533842238 Human Diseases Infectious disease: viral hsa05169 Epstein-Barr virus infection 6/29 205/9376 9.46274179983179 HLA-C/HLA-A/HLA-G/HLA-DRB5/TAPBP/ISG15 6.82382986511984 Human Diseases Infectious disease: viral hsa05163 Human cytomegalovirus infection 6/29 227/9376 8.54564788090536 HLA-C/CCL5/HLA-A/HLA-G/TAPBP/GNG11 6.41019388447254 Human Diseases Cardiovascular disease hsa05416 Viral myocarditis 4/29 70/9376 18.4748768472906 HLA-C/HLA-A/HLA-G/HLA-DRB5 8.17391534421059 Human Diseases Infectious disease: parasitic hsa05143 African trypanosomiasis 3/29 37/9376 26.2143522833178 HBB/HBA2/HBA1 8.55947260794858 Human Diseases Infectious disease: viral hsa05167 Kaposi sarcoma-associated herpesvirus infection 5/29 196/9376 8.24771287825475 HLA-C/HLA-A/HLA-G/GNG11/RPS27A 5.71157903894589 Human Diseases Infectious disease: viral hsa05170 Human immunodeficiency virus 1 infection 5/29 214/9376 7.55398001933613 HLA-C/HLA-A/HLA-G/TAPBP/GNG11 5.4021342380678 Human Diseases Infectious disease: parasitic hsa05144 Malaria 3/29 50/9376 19.3986206896552 HBB/HBA2/HBA1 7.26559320503976 Organismal Systems Immune system hsa04650 Natural killer cell mediated cytotoxicity 4/29 133/9376 9.72361939331086 HLA-C/HLA-A/HLA-G/CD48 5.64370843371306 Cellular Processes Transport and catabolism hsa04145 Phagosome 4/29 155/9376 8.34349276974416 HLA-C/HLA-A/HLA-G/HLA-DRB5 5.13485312191158 Environmental Information Processing Signaling molecules and interaction hsa04514 Cell adhesion molecule (CAM) interaction 4/29 160/9376 8.08275862068966 HLA-C/HLA-A/HLA-G/HLA-DRB5 5.03314816707793 Organismal Systems Immune system hsa04062 Chemokine signaling pathway 4/29 193/9376 6.70073253528676 CCL5/CCL21/XCL2/GNG11 4.45723511762343 Environmental Information Processing Signaling molecules and interaction hsa04061 Viral protein interaction with cytokine and cytokine receptor 3/29 100/9376 9.69931034482759 CCL5/CCL21/XCL2 4.87139078488969 Human Diseases Infectious disease: viral hsa05166 Human T-cell leukemia virus 1 infection 4/29 224/9376 5.77339901477832 HLA-C/HLA-A/HLA-G/HLA-DRB5 4.02756222019625 Cellular Processes Cell growth and death hsa04218 Cellular senescence 3/29 157/9376 6.17790467823413 HLA-C/HLA-A/HLA-G 3.64426949420586 Environmental Information Processing Signaling molecules and interaction hsa04060 Cytokine-cytokine receptor interaction 4/29 298/9376 4.33973617218236 CCL5/CCL21/IL32/XCL2 3.26342562234322 Human Diseases Infectious disease: viral hsa05165 Human papillomavirus infection 4/29 333/9376 3.88360774567671 HLA-C/HLA-A/HLA-G/ISG15 2.98435546557592 Human Diseases Cancer: overview hsa05203 Viral carcinogenesis 3/29 205/9376 4.7313708999159 HLA-C/HLA-A/HLA-G 3.00874595809969 Human Diseases Immune disease hsa05323 Rheumatoid arthritis 2/29 95/9376 6.8065335753176 CCL5/HLA-DRB5 3.16832609086784 Cellular Processes Transport and catabolism hsa04144 Endocytosis 3/29 250/9376 3.87972413793103 HLA-C/HLA-A/HLA-G 2.57056846004798 Metabolism Amino acid metabolism hsa00360 Phenylalanine metabolism 1/29 16/9376 20.2068965517241 MIF 4.28279986228295 Human Diseases Immune disease hsa05310 Asthma 1/29 32/9376 10.1034482758621 HLA-DRB5 2.87318121975862 Human Diseases Infectious disease: viral hsa05164 Influenza A 2/29 173/9376 3.73769184771776 CCL5/HLA-DRB5 2.0243771149717 Metabolism Amino acid metabolism hsa00350 Tyrosine metabolism 1/29 37/9376 8.7381174277726 MIF 2.62684535441867 Organismal Systems Immune system hsa04672 Intestinal immune network for IgA production 1/29 50/9376 6.46620689655172 HLA-DRB5 2.15859853599015 Organismal Systems Digestive system hsa04978 Mineral absorption 1/29 61/9376 5.30016958733748 MT2A 1.87675502360968 Human Diseases Infectious disease: bacterial hsa05131 Shigellosis 2/29 253/9376 2.55581300258961 CCL5/RPS27A 1.39732469911374 Human Diseases Immune disease hsa05321 Inflammatory bowel disease 1/29 66/9376 4.89864158829676 HLA-DRB5 1.7703492623243 Human Diseases Infectious disease: bacterial hsa05120 Epithelial cell signaling in Helicobacter pylori infection 1/29 71/9376 4.55366682855755 CCL5 1.67415710321969 Human Diseases Neurodegenerative disease hsa05012 Parkinson disease 2/29 268/9376 2.41276376737005 MT-CO2/RPS27A 1.30699507184682 Organismal Systems Immune system hsa04622 RIG-I-like receptor signaling pathway 1/29 72/9376 4.4904214559387 ISG15 1.65599027799074 Human Diseases Neurodegenerative disease hsa05020 Prion disease 2/29 275/9376 2.35134796238244 CCL5/MT-CO2 1.26688588261133 Human Diseases Infectious disease: parasitic hsa05140 Leishmaniasis 1/29 78/9376 4.14500442086649 HLA-DRB5 1.55353952313067 Organismal Systems Immune system hsa04623 Cytosolic DNA-sensing pathway 1/29 83/9376 3.89530535936851 CCL5 1.47572001521577 Organismal Systems Circulatory system hsa04260 Cardiac muscle contraction 1/29 87/9376 3.7162108600872 MT-CO2 1.41770914881353 Organismal Systems Nervous system hsa04727 GABAergic synapse 1/29 89/9376 3.63270050368074 GNG11 1.38997584412735 Organismal Systems Immune system hsa04662 B cell receptor signaling pathway 1/29 91/9376 3.55286093217128 IFITM1 1.36303000122669 Human Diseases Substance dependence hsa05032 Morphine addiction 1/29 91/9376 3.55286093217128 GNG11 1.36303000122669 Organismal Systems Immune system hsa04658 Th1 and Th2 cell differentiation 1/29 93/9376 3.47645532072673 HLA-DRB5 1.33683039648362 Organismal Systems Environmental adaptation hsa04713 Circadian entrainment 1/29 97/9376 3.33309633842872 GNG11 1.28651977962713 Human Diseases Infectious disease: bacterial hsa05150 Staphylococcus aureus infection 1/29 99/9376 3.26576105886451 HLA-DRB5 1.26234028834955 Organismal Systems Immune system hsa04640 Hematopoietic cell lineage 1/29 100/9376 3.23310344827586 HLA-DRB5 1.25048068506999 Human Diseases Infectious disease: parasitic hsa05142 Chagas disease 1/29 103/9376 3.13893538667559 CCL5 1.21577907333166 Environmental Information Processing Signal transduction hsa04064 NF-kappa B signaling pathway 1/29 105/9376 3.07914614121511 CCL21 1.19334190478168 Cellular Processes Transport and catabolism hsa04137 Mitophagy - animal 1/29 105/9376 3.07914614121511 RPS27A 1.19334190478168 Organismal Systems Immune system hsa04620 Toll-like receptor signaling pathway 1/29 109/9376 2.96614995254666 CCL5 1.15002907523853 Organismal Systems Immune system hsa04659 Th17 cell differentiation 1/29 109/9376 2.96614995254666 HLA-DRB5 1.15002907523853 Human Diseases Infectious disease: parasitic hsa05145 Toxoplasmosis 1/29 112/9376 2.88669950738916 HLA-DRB5 1.11882198055857 Organismal Systems Nervous system hsa04725 Cholinergic synapse 1/29 115/9376 2.81139430284858 GNG11 1.08863299072842 Organismal Systems Nervous system hsa04726 Serotonergic synapse 1/29 115/9376 2.81139430284858 GNG11 1.08863299072842 Organismal Systems Nervous system hsa04724 Glutamatergic synapse 1/29 116/9376 2.7871581450654 GNG11 1.07878525511729 Environmental Information Processing Signal transduction hsa04668 TNF signaling pathway 1/29 119/9376 2.71689365401333 CCL5 1.04985727016001 Organismal Systems Endocrine system hsa04926 Relaxin signaling pathway 1/29 130/9376 2.48700265251989 GNG11 0.950944105185823 Organismal Systems Nervous system hsa04728 Dopaminergic synapse 1/29 133/9376 2.43090484832772 GNG11 0.925717800863743 Metabolism Energy metabolism hsa00190 Oxidative phosphorylation 1/29 138/9376 2.34282858570715 MT-CO2 0.88515567449106 Environmental Information Processing Signal transduction hsa04371 Apelin signaling pathway 1/29 140/9376 2.30935960591133 GNG11 0.869419767384345 Genetic Information Processing Folding, sorting and degradation hsa04120 Ubiquitin mediated proteolysis 1/29 142/9376 2.27683341427878 RPS27A 0.85394911420448 Human Diseases Immune disease hsa05322 Systemic lupus erythematosus 1/29 143/9376 2.26091150229081 HLA-DRB5 0.846310488525546 Organismal Systems Nervous system hsa04723 Retrograde endocannabinoid signaling 1/29 149/9376 2.16986808609118 GNG11 0.801767196067269 Human Diseases Endocrine and metabolic disease hsa04932 Non-alcoholic fatty liver disease 1/29 157/9376 2.05930155941138 MT-CO2 0.745548749546336 Cellular Processes Transport and catabolism hsa04140 Autophagy - animal 1/29 169/9376 1.91307896347684 RPS27A 0.667177103674059 Human Diseases Infectious disease: bacterial hsa05152 Tuberculosis 1/29 181/9376 1.78624499904744 HLA-DRB5 0.594935429267621 Human Diseases Neurodegenerative disease hsa05022 Pathways of neurodegeneration - multiple diseases 2/29 480/9376 1.34712643678161 MT-CO2/RPS27A 0.434869989296186 Organismal Systems Immune system hsa04621 NOD-like receptor signaling pathway 1/29 187/9376 1.72893232528121 CCL5 0.560818592631444 Human Diseases Substance dependence hsa05034 Alcoholism 1/29 191/9376 1.69272431846904 GNG11 0.538748474153323 NA NA hsa04082 Neuroactive ligand signaling 1/29 199/9376 1.62467509963611 GNG11 0.496111030140739 Human Diseases Cardiovascular disease hsa05415 Diabetic cardiomyopathy 1/29 205/9376 1.5771236333053 MT-CO2 0.46535668675292 Human Diseases Cardiovascular disease hsa05417 Lipid and atherosclerosis 1/29 216/9376 1.49680715197957 CCL5 0.411448509890155 NA NA hsa04081 Hormone signaling 1/29 219/9376 1.4763029444182 GNG11 0.397262189963334 Human Diseases Cancer: overview hsa05208 Chemical carcinogenesis - reactive oxygen species 1/29 227/9376 1.42427464681756 MT-CO2 0.360430646816818 Organismal Systems Environmental adaptation hsa04714 Thermogenesis 1/29 235/9376 1.37578870139398 MT-CO2 0.324959554572881 Environmental Information Processing Signal transduction hsa04014 Ras signaling pathway 1/29 238/9376 1.35844682700666 GNG11 0.311986755588627 NA NA hsa04517 IgSF CAM signaling 1/29 299/9376 1.08130550109561 CD48 0.0795853028046854 Human Diseases Neurodegenerative disease hsa05016 Huntington disease 1/29 308/9376 1.04970891177788 MT-CO2 0.0494085801791355 Environmental Information Processing Signal transduction hsa04151 PI3K-Akt signaling pathway 1/29 362/9376 0.893122499523719 GNG11 -0.115512853601309 Human Diseases Neurodegenerative disease hsa05014 Amyotrophic lateral sclerosis 1/29 368/9376 0.87856071964018 MT-CO2 -0.132378489521596 Human Diseases Neurodegenerative disease hsa05010 Alzheimer disease 1/29 388/9376 0.833274084607181 MT-CO2 -0.186825415705234