category subcategory ID Description GeneRatio BgRatio FoldEnrichment geneName zScore Human Diseases Infectious disease: parasitic hsa05143 African trypanosomiasis 3/17 37/9376 44.7186009538951 HBA2/HBB/HBA1 11.3556580212761 Human Diseases Infectious disease: parasitic hsa05144 Malaria 3/17 50/9376 33.0917647058823 HBA2/HBB/HBA1 9.69675161529007 Human Diseases Cardiovascular disease hsa05416 Viral myocarditis 3/17 70/9376 23.636974789916 HLA-DRB5/HLA-C/CCND1 8.10179515537976 NA NA hsa04382 Cornified envelope formation 4/17 217/9376 10.1664407698563 PCSK6/KRT6A/S100A10/COL17A1 5.82239880625748 Human Diseases Immune disease hsa05330 Allograft rejection 2/17 39/9376 28.2835595776772 HLA-DRB5/HLA-C 7.27654182061185 Human Diseases Endocrine and metabolic disease hsa04940 Type I diabetes mellitus 2/17 44/9376 25.0695187165775 HLA-DRB5/HLA-C 6.82027293736173 Human Diseases Immune disease hsa05332 Graft-versus-host disease 2/17 45/9376 24.5124183006536 HLA-DRB5/HLA-C 6.73805942641696 Human Diseases Infectious disease: viral hsa05168 Herpes simplex virus 1 infection 3/17 180/9376 9.1921568627451 HLA-DRB5/HLA-C/BST2 4.72966527337058 Human Diseases Immune disease hsa05320 Autoimmune thyroid disease 2/17 54/9376 20.4270152505447 HLA-DRB5/HLA-C 6.10160075288271 Human Diseases Infectious disease: viral hsa05167 Kaposi sarcoma-associated herpesvirus infection 3/17 196/9376 8.44177671068427 HLA-C/CCND1/CCR1 4.48723387175643 Human Diseases Infectious disease: viral hsa05169 Epstein-Barr virus infection 3/17 205/9376 8.07116212338594 HLA-DRB5/HLA-C/CCND1 4.36269401087597 Human Diseases Infectious disease: viral hsa05166 Human T-cell leukemia virus 1 infection 3/17 224/9376 7.38655462184874 HLA-DRB5/HLA-C/CCND1 4.12313931823763 Human Diseases Infectious disease: viral hsa05163 Human cytomegalovirus infection 3/17 227/9376 7.28893495724281 HLA-C/CCND1/CCR1 4.08788427882431 Organismal Systems Immune system hsa04612 Antigen processing and presentation 2/17 82/9376 13.4519368723099 HLA-DRB5/HLA-C 4.82656187012064 Human Diseases Cancer: specific types hsa05222 Small cell lung cancer 2/17 93/9376 11.8608475648324 CCND1/BIRC7 4.48597028596381 Human Diseases Infectious disease: parasitic hsa05145 Toxoplasmosis 2/17 112/9376 9.84873949579832 HLA-DRB5/BIRC7 4.01500900057076 Cellular Processes Transport and catabolism hsa04145 Phagosome 2/17 155/9376 7.11650853889943 HLA-DRB5/HLA-C 3.27247094786937 Cellular Processes Cell growth and death hsa04218 Cellular senescence 2/17 157/9376 7.02585237916823 HLA-C/CCND1 3.24505290878925 Environmental Information Processing Signaling molecules and interaction hsa04514 Cell adhesion molecule (CAM) interaction 2/17 160/9376 6.89411764705882 HLA-DRB5/HLA-C 3.2048147715437 Environmental Information Processing Signal transduction hsa04310 Wnt signaling pathway 2/17 178/9376 6.1969596827495 CCND1/SFRP1 2.98337620428874 Human Diseases Cancer: overview hsa05203 Viral carcinogenesis 2/17 205/9376 5.38077474892396 HLA-C/CCND1 2.70280604894061 Human Diseases Infectious disease: viral hsa05170 Human immunodeficiency virus 1 infection 2/17 214/9376 5.1544804837823 HLA-C/BST2 2.62013604280309 Cellular Processes Cell growth and death hsa04215 Apoptosis - multiple species 1/17 32/9376 17.2352941176471 BIRC7 3.92070449158243 Human Diseases Immune disease hsa05310 Asthma 1/17 32/9376 17.2352941176471 HLA-DRB5 3.92070449158243 Genetic Information Processing Translation hsa03010 Ribosome 2/17 222/9376 4.96873343932167 RPS4Y1/RPS26 2.55045895563903 Human Diseases Cancer: specific types hsa05216 Thyroid cancer 1/17 37/9376 14.906200317965 CCND1 3.61205646431151 Human Diseases Infectious disease: viral hsa05171 Coronavirus disease - COVID-19 2/17 238/9376 4.63470093919921 RPS4Y1/RPS26 2.42062191100492 Human Diseases Cancer: specific types hsa05219 Bladder cancer 1/17 41/9376 13.4519368723099 CCND1 3.40539153967678 Organismal Systems Immune system hsa04672 Intestinal immune network for IgA production 1/17 50/9376 11.0305882352941 HLA-DRB5 3.03081253288229 Environmental Information Processing Signal transduction hsa04340 Hedgehog signaling pathway 1/17 56/9376 9.84873949579832 CCND1 2.83049793493705 Human Diseases Cancer: specific types hsa05213 Endometrial cancer 1/17 59/9376 9.34795613160519 CCND1 2.74134371421824 Human Diseases Immune disease hsa05321 Inflammatory bowel disease 1/17 66/9376 8.35650623885918 HLA-DRB5 2.55601919042046 Human Diseases Cancer: specific types hsa05221 Acute myeloid leukemia 1/17 68/9376 8.11072664359862 CCND1 2.50804675154453 Human Diseases Infectious disease: viral hsa05165 Human papillomavirus infection 2/17 333/9376 3.31248895954778 HLA-C/CCND1 1.83122156704103 Organismal Systems Endocrine system hsa04917 Prolactin signaling pathway 1/17 71/9376 7.76801988400994 CCND1 2.43965259140327 Genetic Information Processing Information processing in viruses hsa03250 Viral life cycle - HIV-1 1/17 73/9376 7.55519742143433 BST2 2.39624417742993 Human Diseases Cancer: specific types hsa05218 Melanoma 1/17 73/9376 7.55519742143433 CCND1 2.39624417742993 Human Diseases Cancer: specific types hsa05223 Non-small cell lung cancer 1/17 73/9376 7.55519742143433 CCND1 2.39624417742993 Cellular Processes Cell growth and death hsa04115 p53 signaling pathway 1/17 75/9376 7.35372549019608 CCND1 2.35445086810679 Human Diseases Cancer: specific types hsa05214 Glioma 1/17 76/9376 7.25696594427245 CCND1 2.33412703200873 Human Diseases Cancer: specific types hsa05212 Pancreatic cancer 1/17 77/9376 7.16271963330787 CCND1 2.31416874838293 Human Diseases Cancer: specific types hsa05220 Chronic myeloid leukemia 1/17 77/9376 7.16271963330787 CCND1 2.31416874838293 Human Diseases Infectious disease: parasitic hsa05140 Leishmaniasis 1/17 78/9376 7.07088989441931 HLA-DRB5 2.29456445662806 Human Diseases Cancer: specific types hsa05210 Colorectal cancer 1/17 87/9376 6.3394185260311 CCND1 2.1323794284582 Organismal Systems Immune system hsa04658 Th1 and Th2 cell differentiation 1/17 93/9376 5.93042378241619 HLA-DRB5 2.03646487560934 Human Diseases Immune disease hsa05323 Rheumatoid arthritis 1/17 95/9376 5.80557275541796 HLA-DRB5 2.00634192481458 Human Diseases Drug resistance: antineoplastic hsa01522 Endocrine resistance 1/17 99/9376 5.57100415923945 CCND1 1.9485915311465 Human Diseases Infectious disease: bacterial hsa05150 Staphylococcus aureus infection 1/17 99/9376 5.57100415923945 HLA-DRB5 1.9485915311465 Environmental Information Processing Signaling molecules and interaction hsa04061 Viral protein interaction with cytokine and cytokine receptor 1/17 100/9376 5.51529411764706 CCR1 1.93464395169406 Organismal Systems Immune system hsa04640 Hematopoietic cell lineage 1/17 100/9376 5.51529411764706 HLA-DRB5 1.93464395169406 Human Diseases Endocrine and metabolic disease hsa04933 AGE-RAGE signaling pathway in diabetic complications 1/17 101/9376 5.46068724519511 CCND1 1.92088284231543 Organismal Systems Digestive system hsa04974 Protein digestion and absorption 1/17 103/9376 5.35465448315248 COL17A1 1.89390224846536 Human Diseases Cancer: specific types hsa05215 Prostate cancer 1/17 106/9376 5.2031076581576 CCND1 1.85472256168215 Organismal Systems Immune system hsa04659 Th17 cell differentiation 1/17 109/9376 5.05990286022666 HLA-DRB5 1.81699898711516 Environmental Information Processing Signal transduction hsa04152 AMPK signaling pathway 1/17 122/9376 4.52073288331726 CCND1 1.66818272521563 Organismal Systems Endocrine system hsa04919 Thyroid hormone signaling pathway 1/17 122/9376 4.52073288331726 CCND1 1.66818272521563 Environmental Information Processing Signal transduction hsa04068 FoxO signaling pathway 1/17 133/9376 4.1468376824414 CCND1 1.55771879959416 Organismal Systems Immune system hsa04650 Natural killer cell mediated cytotoxicity 1/17 133/9376 4.1468376824414 HLA-C 1.55771879959416 Human Diseases Infectious disease: viral hsa05162 Measles 1/17 136/9376 4.05536332179931 CCND1 1.52964870950399 Environmental Information Processing Signal transduction hsa04371 Apelin signaling pathway 1/17 140/9376 3.93949579831933 CCND1 1.4934485815249 Genetic Information Processing Folding, sorting and degradation hsa04120 Ubiquitin mediated proteolysis 1/17 142/9376 3.88400994200497 BIRC7 1.47584709752556 Human Diseases Immune disease hsa05322 Systemic lupus erythematosus 1/17 143/9376 3.85684903331962 HLA-DRB5 1.4671660449315 Human Diseases Endocrine and metabolic disease hsa04936 Alcoholic liver disease 1/17 144/9376 3.83006535947712 CCND1 1.4585629882392 Human Diseases Cancer: specific types hsa05224 Breast cancer 1/17 148/9376 3.72655007949126 CCND1 1.42490502803072 Human Diseases Cancer: specific types hsa05226 Gastric cancer 1/17 150/9376 3.67686274509804 CCND1 1.40851145444454 NA NA hsa04518 Integrin signaling 1/17 154/9376 3.58135981665393 CCND1 1.37654914797868 Organismal Systems Endocrine system hsa04921 Oxytocin signaling pathway 1/17 154/9376 3.58135981665393 CCND1 1.37654914797868 Human Diseases Endocrine and metabolic disease hsa04934 Cushing syndrome 1/17 155/9376 3.55825426944972 CCND1 1.36872412108875 Human Diseases Infectious disease: viral hsa05160 Hepatitis C 1/17 156/9376 3.53544494720965 CCND1 1.36096325250483 Environmental Information Processing Signal transduction hsa04390 Hippo signaling pathway 1/17 157/9376 3.51292618958411 CCND1 1.35326555115647 Cellular Processes Cell growth and death hsa04110 Cell cycle 1/17 158/9376 3.49069247952345 CCND1 1.34563004764348 Environmental Information Processing Signal transduction hsa04630 JAK-STAT signaling pathway 1/17 168/9376 3.28291316526611 CCND1 1.27249695985892 Cellular Processes Cellular community - eukaryotes hsa04530 Tight junction 1/17 170/9376 3.24429065743945 CCND1 1.25852965170782 Human Diseases Cancer: specific types hsa05225 Hepatocellular carcinoma 1/17 170/9376 3.24429065743945 CCND1 1.25852965170782 Human Diseases Infectious disease: viral hsa05164 Influenza A 1/17 173/9376 3.18803128187691 HLA-DRB5 1.23796179641962 Human Diseases Infectious disease: bacterial hsa05152 Tuberculosis 1/17 181/9376 3.04712382190445 HLA-DRB5 1.18523074337868 Genetic Information Processing Translation hsa03008 Ribosome biogenesis in eukaryotes 1/17 183/9376 3.01382192221151 SNORD3A 1.17250135769933 Organismal Systems Immune system hsa04062 Chemokine signaling pathway 1/17 193/9376 2.85766534593112 CCR1 1.11134581179662 Cellular Processes Cellular community - eukaryotes hsa04510 Focal adhesion 1/17 203/9376 2.71689365401333 CCND1 1.05397690070587 Human Diseases Cancer: overview hsa05205 Proteoglycans in cancer 1/17 204/9376 2.70357554786621 CCND1 1.04843095193576 Human Diseases Cancer: overview hsa05207 Chemical carcinogenesis - receptor activation 1/17 217/9376 2.54161019246408 CCND1 0.979209877604209 Human Diseases Infectious disease: bacterial hsa05132 Salmonella infection 1/17 248/9376 2.22390891840607 S100A10 0.832496659236042 Cellular Processes Transport and catabolism hsa04144 Endocytosis 1/17 250/9376 2.20611764705882 HLA-C 0.823786781857701 Environmental Information Processing Signaling molecules and interaction hsa04060 Cytokine-cytokine receptor interaction 1/17 298/9376 1.8507698381366 CCR1 0.636092833703949 Human Diseases Cancer: overview hsa05206 MicroRNAs in cancer 1/17 323/9376 1.70752139865234 CCND1 0.551492938117411 Environmental Information Processing Signal transduction hsa04151 PI3K-Akt signaling pathway 1/17 362/9376 1.52356191095223 CCND1 0.432971118776819 NA NA hsa04519 Cadherin signaling 1/17 404/9376 1.36517181129878 KRT6A 0.319770702496366