category subcategory ID Description GeneRatio BgRatio FoldEnrichment geneName zScore Organismal Systems Immune system hsa04612 Antigen processing and presentation 5/14 82/9376 40.8362369337979 HLA-C/B2M/HLA-A/CD74/HLA-DRB1 14.0103581217528 Human Diseases Infectious disease: viral hsa05168 Herpes simplex virus 1 infection 6/14 180/9376 22.3238095238095 HLA-C/B2M/HLA-A/CD74/CCL5/HLA-DRB1 11.1703531469265 Human Diseases Infectious disease: viral hsa05169 Epstein-Barr virus infection 5/14 205/9376 16.3344947735192 HLA-C/B2M/HLA-A/HLA-DRB1/ISG15 8.58427048017604 Human Diseases Immune disease hsa05330 Allograft rejection 3/14 39/9376 51.5164835164835 HLA-C/HLA-A/HLA-DRB1 12.2243865165832 Human Diseases Endocrine and metabolic disease hsa04940 Type I diabetes mellitus 3/14 44/9376 45.6623376623377 HLA-C/HLA-A/HLA-DRB1 11.4827460846245 Human Diseases Immune disease hsa05332 Graft-versus-host disease 3/14 45/9376 44.647619047619 HLA-C/HLA-A/HLA-DRB1 11.349273396137 Human Diseases Immune disease hsa05320 Autoimmune thyroid disease 3/14 54/9376 37.2063492063492 HLA-C/HLA-A/HLA-DRB1 10.3179258879616 Human Diseases Cardiovascular disease hsa05416 Viral myocarditis 3/14 70/9376 28.7020408163265 HLA-C/HLA-A/HLA-DRB1 8.99589957084731 Human Diseases Infectious disease: viral hsa05166 Human T-cell leukemia virus 1 infection 4/14 224/9376 11.9591836734694 HLA-C/B2M/HLA-A/HLA-DRB1 6.41962333110302 Human Diseases Infectious disease: viral hsa05163 Human cytomegalovirus infection 4/14 227/9376 11.8011327879169 HLA-C/B2M/HLA-A/CCL5 6.370312797062 Human Diseases Infectious disease: viral hsa05171 Coronavirus disease - COVID-19 4/14 238/9376 11.2557022809124 C1QB/C1QA/ISG15/RPS26 6.19717334537852 Human Diseases Infectious disease: bacterial hsa05150 Staphylococcus aureus infection 3/14 99/9376 20.2943722943723 C1QB/C1QA/HLA-DRB1 7.46293760818596 Human Diseases Infectious disease: parasitic hsa05142 Chagas disease 3/14 103/9376 19.5062413314841 C1QB/CCL5/C1QA 7.30284430046652 Human Diseases Immune disease hsa05322 Systemic lupus erythematosus 3/14 143/9376 14.0499500499501 C1QB/C1QA/HLA-DRB1 6.08094097550957 Cellular Processes Transport and catabolism hsa04145 Phagosome 3/14 155/9376 12.9622119815668 HLA-C/HLA-A/HLA-DRB1 5.80702465547256 Environmental Information Processing Signaling molecules and interaction hsa04514 Cell adhesion molecule (CAM) interaction 3/14 160/9376 12.5571428571429 HLA-C/HLA-A/HLA-DRB1 5.70170281930307 Cellular Processes Cell growth and death hsa04216 Ferroptosis 2/14 42/9376 31.891156462585 FTH1/FTL 7.75872308305927 Metabolism Metabolism of cofactors and vitamins hsa00860 Porphyrin metabolism 2/14 46/9376 29.1180124223602 FTH1/FTL 7.39244411533435 Human Diseases Infectious disease: viral hsa05170 Human immunodeficiency virus 1 infection 3/14 214/9376 9.38851802403204 HLA-C/B2M/HLA-A 4.80023304832795 Organismal Systems Digestive system hsa04978 Mineral absorption 2/14 61/9376 21.9578454332553 FTH1/FTL 6.35017155973011 Human Diseases Infectious disease: bacterial hsa05133 Pertussis 2/14 78/9376 17.1721611721612 C1QB/C1QA 5.54607743476852 Human Diseases Neurodegenerative disease hsa05020 Prion disease 3/14 275/9376 7.30597402597403 C1QB/CCL5/C1QA 4.1043019594155 Organismal Systems Immune system hsa04610 Complement and coagulation cascades 2/14 88/9376 15.2207792207792 C1QB/C1QA 5.18285387274722 Human Diseases Immune disease hsa05323 Rheumatoid arthritis 2/14 95/9376 14.0992481203008 CCL5/HLA-DRB1 4.96222122921589 Environmental Information Processing Signaling molecules and interaction hsa04061 Viral protein interaction with cytokine and cytokine receptor 2/14 100/9376 13.3942857142857 CCL21/CCL5 4.81844017241742 Human Diseases Infectious disease: viral hsa05165 Human papillomavirus infection 3/14 333/9376 6.03346203346203 HLA-C/HLA-A/ISG15 3.61657924922403 Organismal Systems Immune system hsa04650 Natural killer cell mediated cytotoxicity 2/14 133/9376 10.0708915145005 HLA-C/HLA-A 4.07412786016014 Human Diseases Endocrine and metabolic disease hsa04936 Alcoholic liver disease 2/14 144/9376 9.3015873015873 C1QB/C1QA 3.88203838399877 Cellular Processes Transport and catabolism hsa04148 Efferocytosis 2/14 157/9376 8.53139217470428 C1QB/C1QA 3.68000593537639 Cellular Processes Cell growth and death hsa04218 Cellular senescence 2/14 157/9376 8.53139217470428 HLA-C/HLA-A 3.68000593537639 Cellular Processes Cell growth and death hsa04217 Necroptosis 2/14 168/9376 7.97278911564626 FTH1/FTL 3.52649972114334 Human Diseases Infectious disease: viral hsa05164 Influenza A 2/14 173/9376 7.74236168455822 CCL5/HLA-DRB1 3.46127195988316 Human Diseases Infectious disease: bacterial hsa05152 Tuberculosis 2/14 181/9376 7.40015785319653 CD74/HLA-DRB1 3.36216825902243 Organismal Systems Immune system hsa04062 Chemokine signaling pathway 2/14 193/9376 6.940044411547 CCL21/CCL5 3.22434416533275 Human Diseases Infectious disease: viral hsa05167 Kaposi sarcoma-associated herpesvirus infection 2/14 196/9376 6.83381924198251 HLA-C/HLA-A 3.19172158973535 Human Diseases Cancer: overview hsa05203 Viral carcinogenesis 2/14 205/9376 6.53379790940767 HLA-C/HLA-A 3.09782739754955 Human Diseases Immune disease hsa05310 Asthma 1/14 32/9376 20.9285714285714 HLA-DRB1 4.36666705455723 Cellular Processes Transport and catabolism hsa04144 Endocytosis 2/14 250/9376 5.35771428571429 HLA-C/HLA-A 2.70056019463633 Environmental Information Processing Signaling molecules and interaction hsa04060 Cytokine-cytokine receptor interaction 2/14 298/9376 4.49472674976031 CCL21/CCL5 2.37078190980258 Organismal Systems Immune system hsa04672 Intestinal immune network for IgA production 1/14 50/9376 13.3942857142857 HLA-DRB1 3.39800597022494 Human Diseases Immune disease hsa05321 Inflammatory bowel disease 1/14 66/9376 10.1471861471861 HLA-DRB1 2.88369936687863 Human Diseases Infectious disease: bacterial hsa05120 Epithelial cell signaling in Helicobacter pylori infection 1/14 71/9376 9.43259557344065 CCL5 2.75802116976318 Organismal Systems Immune system hsa04622 RIG-I-like receptor signaling pathway 1/14 72/9376 9.3015873015873 ISG15 2.73437373894825 Human Diseases Infectious disease: parasitic hsa05140 Leishmaniasis 1/14 78/9376 8.58608058608059 HLA-DRB1 2.60156882613943 Organismal Systems Immune system hsa04623 Cytosolic DNA-sensing pathway 1/14 83/9376 8.06884681583477 CCL5 2.50135300260879 Organismal Systems Immune system hsa04658 Th1 and Th2 cell differentiation 1/14 93/9376 7.20122887864823 HLA-DRB1 2.32402287019749 Organismal Systems Immune system hsa04640 Hematopoietic cell lineage 1/14 100/9376 6.69714285714286 HLA-DRB1 2.21483856703558 Environmental Information Processing Signal transduction hsa04064 NF-kappa B signaling pathway 1/14 105/9376 6.37823129251701 CCL21 2.14306908750037 Organismal Systems Immune system hsa04620 Toll-like receptor signaling pathway 1/14 109/9376 6.14416775884666 CCL5 2.08893116017768 Organismal Systems Immune system hsa04659 Th17 cell differentiation 1/14 109/9376 6.14416775884666 HLA-DRB1 2.08893116017768 Human Diseases Infectious disease: parasitic hsa05145 Toxoplasmosis 1/14 112/9376 5.97959183673469 HLA-DRB1 2.05007062181063 Environmental Information Processing Signal transduction hsa04668 TNF signaling pathway 1/14 119/9376 5.62785114045618 CCL5 1.96464038648325 Organismal Systems Immune system hsa04621 NOD-like receptor signaling pathway 1/14 187/9376 3.58135981665393 CCL5 1.378797732038 Human Diseases Cardiovascular disease hsa05417 Lipid and atherosclerosis 1/14 216/9376 3.1005291005291 CCL5 1.20773924561396 Genetic Information Processing Translation hsa03010 Ribosome 1/14 222/9376 3.01673101673102 RPS26 1.17593779375984 Cellular Processes Transport and catabolism hsa04142 Lysosome biogenesis 1/14 250/9376 2.67885714285714 LAPTM5 1.04042038445339 Human Diseases Infectious disease: bacterial hsa05131 Shigellosis 1/14 253/9376 2.64709203839639 CCL5 1.02700989686302