ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0023023	MHC protein complex binding	8/335	37/18639	0.216216216216216	12.0300121016539	2.45543252328117e-07	0.000158620941003964
GO:0042605	peptide antigen binding	8/335	45/18639	0.177777777777778	9.89134328358209	1.20964408797588e-06	0.000390715040416208
GO:0023026	MHC class II protein complex binding	6/335	27/18639	0.222222222222222	12.3641791044776	6.93655209102264e-06	0.00149367088360021
GO:0003823	antigen binding	13/335	174/18639	0.0747126436781609	4.15692228512609	1.64179316438867e-05	0.00225492816361161
GO:0003735	structural constituent of ribosome	13/335	175/18639	0.0742857142857143	4.1331684434968	1.7453004362319e-05	0.00225492816361161
GO:0045296	cadherin binding	18/335	334/18639	0.0538922155688623	2.99849852533738	3.74572361874202e-05	0.00403289576284558
GO:0042277	peptide binding	15/335	249/18639	0.0602409638554217	3.35173529940658	4.76221856321565e-05	0.00439484741691044
GO:0097718	disordered domain specific binding	5/335	28/18639	0.178571428571429	9.93550106609808	0.000127326575056755	0.0102816209358329
GO:0034987	immunoglobulin receptor binding	4/335	19/18639	0.210526315789474	11.7134328358209	0.000320881894637148	0.0230321893261775
GO:0140313	molecular sequestering activity	6/335	55/18639	0.109090909090909	6.06968792401628	0.000445157227422203	0.0287571568914743
GO:0031720	haptoglobin binding	3/335	10/18639	0.3	16.6916417910448	0.00062868466878564	0.0338151431402856
GO:0032395	MHC class II receptor activity	3/335	10/18639	0.3	16.6916417910448	0.00062868466878564	0.0338151431402856
GO:0005178	integrin binding	10/335	161/18639	0.062111801242236	3.45582645777325	0.000680490496631134	0.0338151431402856
GO:0019107	myristoyltransferase activity	3/335	11/18639	0.272727272727273	15.1742198100407	0.000852961651281567	0.0393580876234209
GO:0005201	extracellular matrix structural constituent	10/335	168/18639	0.0595238095238095	3.31183368869936	0.000944454056442	0.0406744880307688
GO:0050840	extracellular matrix binding	6/335	67/18639	0.0895522388059701	4.98257963911784	0.00128002829019508	0.0516811422166263
GO:0019789	SUMO transferase activity	4/335	28/18639	0.142857142857143	7.94840085287847	0.00149231542185829	0.056707986030615
GO:0043236	laminin binding	4/335	29/18639	0.137931034482759	7.67431806484817	0.00170682938559614	0.0612562101719503
GO:0005344	oxygen carrier activity	3/335	14/18639	0.214285714285714	11.9226012793177	0.00180783957381418	0.0614665455096822
GO:0140375	immune receptor activity	9/335	156/18639	0.0576923076923077	3.20993111366246	0.00208123983517723	0.0672240466762247
GO:0019902	phosphatase binding	10/335	190/18639	0.0526315789473684	2.92835820895522	0.00236540028192972	0.0727642181965048
GO:0140311	protein sequestering activity	4/335	33/18639	0.121212121212121	6.74409769335143	0.00277950712793349	0.0805567814849563
GO:0003779	actin binding	17/335	443/18639	0.0383747178329571	2.13512347966713	0.00286812070302476	0.0805567814849563
GO:0019825	oxygen binding	4/335	34/18639	0.117647058823529	6.54574187884109	0.00310610406565688	0.0836059677672644
GO:0016209	antioxidant activity	6/335	86/18639	0.0697674418604651	3.88177716070809	0.00454214245894462	0.117368961139129
GO:0051020	GTPase binding	13/335	315/18639	0.0412698412698413	2.29620469083156	0.00478165018727761	0.11880561619159
GO:0140104	molecular carrier activity	11/335	249/18639	0.0441767068273092	2.45793921956483	0.00557336578615608	0.125337346297326
GO:0061791	GTPase motor activity	4/335	40/18639	0.1	5.56388059701493	0.00562659913718645	0.125337346297326
GO:1990606	membrane scission GTPase motor activity	4/335	40/18639	0.1	5.56388059701493	0.00562659913718645	0.125337346297326
GO:0140297	DNA-binding transcription factor binding	17/335	488/18639	0.0348360655737705	1.93823709322241	0.00742798099216855	0.157573279286076
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	3/335	23/18639	0.130434782608696	7.25723556132381	0.00780548751881491	0.157573279286076
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	3/335	23/18639	0.130434782608696	7.25723556132381	0.00780548751881491	0.157573279286076
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	3/335	25/18639	0.12	6.67665671641791	0.00987278843563078	0.193267313012651
GO:0016763	pentosyltransferase activity	4/335	49/18639	0.0816326530612245	4.54194334450198	0.0115035525212877	0.218567497904466
GO:0005031	tumor necrosis factor receptor activity	2/335	10/18639	0.2	11.1277611940299	0.0131753991039708	0.218728982457117
GO:0005381	iron ion transmembrane transporter activity	2/335	10/18639	0.2	11.1277611940299	0.0131753991039708	0.218728982457117
GO:0008239	dipeptidyl-peptidase activity	2/335	10/18639	0.2	11.1277611940299	0.0131753991039708	0.218728982457117
GO:0070513	death domain binding	2/335	10/18639	0.2	11.1277611940299	0.0131753991039708	0.218728982457117
GO:0019787	ubiquitin-like protein transferase activity	16/335	479/18639	0.0334029227557411	1.85849873804256	0.0133823056433191	0.218728982457117
GO:0031267	small GTPase binding	11/335	283/18639	0.03886925795053	2.16263910131322	0.0137595292074171	0.218728982457117
GO:0005080	protein kinase C binding	4/335	52/18639	0.0769230769230769	4.27990815154994	0.0140978187031372	0.218728982457117
GO:0048306	calcium-dependent protein binding	5/335	80/18639	0.0625	3.47742537313433	0.0146051760465326	0.218728982457117
GO:0019955	cytokine binding	7/335	144/18639	0.0486111111111111	2.70466417910448	0.0154384695382776	0.218728982457117
GO:0019864	IgG binding	2/335	11/18639	0.181818181818182	10.1161465400271	0.0159137185379017	0.218728982457117
GO:0032050	clathrin heavy chain binding	2/335	11/18639	0.181818181818182	10.1161465400271	0.0159137185379017	0.218728982457117
GO:0042608	T cell receptor binding	2/335	11/18639	0.181818181818182	10.1161465400271	0.0159137185379017	0.218728982457117
GO:0050786	RAGE receptor binding	2/335	11/18639	0.181818181818182	10.1161465400271	0.0159137185379017	0.218728982457117
GO:0019887	protein kinase regulator activity	10/335	255/18639	0.0392156862745098	2.1819139596137	0.0173738543818278	0.23157738114239
GO:0061659	ubiquitin-like protein ligase activity	13/335	372/18639	0.0349462365591398	1.94436687530091	0.0175654669906767	0.23157738114239
GO:0016755	aminoacyltransferase activity	16/335	496/18639	0.032258064516129	1.79480019258546	0.0179950799792414	0.232496433331798
GO:0004859	phospholipase inhibitor activity	2/335	12/18639	0.166666666666667	9.27313432835821	0.0188720237477011	0.233915568954048
GO:0042301	phosphate ion binding	2/335	12/18639	0.166666666666667	9.27313432835821	0.0188720237477011	0.233915568954048
GO:0016504	peptidase activator activity	4/335	57/18639	0.0701754385964912	3.9044776119403	0.0191912154095426	0.233915568954048
GO:0019956	chemokine binding	3/335	33/18639	0.0909090909090909	5.05807327001357	0.0210827078004678	0.245497503274605
GO:0004197	cysteine-type endopeptidase activity	5/335	88/18639	0.0568181818181818	3.16129579375848	0.0212190700333203	0.245497503274605
GO:0015459	potassium channel regulator activity	4/335	59/18639	0.0677966101694915	3.77212243865419	0.0215081647361992	0.245497503274605
GO:0005035	death receptor activity	2/335	13/18639	0.153846153846154	8.55981630309989	0.0220415715014351	0.245497503274605
GO:0031994	insulin-like growth factor I binding	2/335	13/18639	0.153846153846154	8.55981630309989	0.0220415715014351	0.245497503274605
GO:0019763	immunoglobulin receptor activity	2/335	14/18639	0.142857142857143	7.94840085287847	0.0254138601560386	0.278260231538999
GO:0005125	cytokine activity	9/335	234/18639	0.0384615384615385	2.13995407577497	0.0260625210033206	0.280606476135752
GO:0061630	ubiquitin protein ligase activity	12/335	353/18639	0.0339943342776204	1.89140416895692	0.026523224872639	0.280885299470899
GO:0042826	histone deacetylase binding	6/335	127/18639	0.047244094488189	2.62860500646374	0.0272821528669702	0.284262431484883
GO:0043394	proteoglycan binding	3/335	37/18639	0.0810810810810811	4.51125453812021	0.0284954637679651	0.285373672962743
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	2/335	15/18639	0.133333333333333	7.41850746268657	0.0289806238400039	0.285373672962743
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	2/335	15/18639	0.133333333333333	7.41850746268657	0.0289806238400039	0.285373672962743
GO:0019843	rRNA binding	4/335	65/18639	0.0615384615384615	3.42392652123995	0.0294522697171388	0.285373672962743
GO:0003714	transcription corepressor activity	8/335	204/18639	0.0392156862745098	2.1819139596137	0.0315391316067731	0.285373672962743
GO:0044389	ubiquitin-like protein ligase binding	11/335	322/18639	0.0341614906832298	1.90070455177529	0.0318271676374027	0.285373672962743
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	2/335	16/18639	0.125	6.95485074626866	0.0327338267661481	0.285373672962743
GO:0005521	lamin binding	2/335	16/18639	0.125	6.95485074626866	0.0327338267661481	0.285373672962743
GO:0008142	oxysterol binding	2/335	16/18639	0.125	6.95485074626866	0.0327338267661481	0.285373672962743
GO:0055102	lipase inhibitor activity	2/335	16/18639	0.125	6.95485074626866	0.0327338267661481	0.285373672962743
GO:0004842	ubiquitin-protein transferase activity	14/335	449/18639	0.0311804008908686	1.73484027523851	0.0331222236275963	0.285373672962743
GO:0032934	sterol binding	4/335	68/18639	0.0588235294117647	3.27287093942054	0.033994443026285	0.285373672962743
GO:0004177	aminopeptidase activity	3/335	40/18639	0.075	4.17291044776119	0.0348455719512968	0.285373672962743
GO:0019207	kinase regulator activity	10/335	287/18639	0.0348432055749129	1.9386343543606	0.0353273403843545	0.285373672962743
GO:0051015	actin filament binding	8/335	209/18639	0.0382775119617225	2.12971506105834	0.0356257231535901	0.285373672962743
GO:0016779	nucleotidyltransferase activity	6/335	136/18639	0.0441176470588235	2.45465320456541	0.0363698117734896	0.285373672962743
GO:0019838	growth factor binding	6/335	136/18639	0.0441176470588235	2.45465320456541	0.0363698117734896	0.285373672962743
GO:0044325	transmembrane transporter binding	6/335	136/18639	0.0441176470588235	2.45465320456541	0.0363698117734896	0.285373672962743
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	2/335	17/18639	0.117647058823529	6.54574187884109	0.0366656576716837	0.285373672962743
GO:0019198	transmembrane receptor protein phosphatase activity	2/335	17/18639	0.117647058823529	6.54574187884109	0.0366656576716837	0.285373672962743
GO:0030169	low-density lipoprotein particle binding	2/335	17/18639	0.117647058823529	6.54574187884109	0.0366656576716837	0.285373672962743
GO:0042287	MHC protein binding	3/335	41/18639	0.0731707317073171	4.07113214415726	0.0371111563052746	0.285402463966755
GO:0042056	chemoattractant activity	3/335	42/18639	0.0714285714285714	3.97420042643923	0.0394504066192042	0.299823090305952
GO:0005518	collagen binding	4/335	72/18639	0.0555555555555556	3.0910447761194	0.0406502759515744	0.302718008636059
GO:0070064	proline-rich region binding	2/335	18/18639	0.111111111111111	6.18208955223881	0.0407685243828748	0.302718008636059
GO:0001664	G protein-coupled receptor binding	10/335	297/18639	0.0336700336700337	1.8733604703754	0.0429199737668024	0.3150716256063
GO:0005520	insulin-like growth factor binding	2/335	19/18639	0.105263157894737	5.85671641791045	0.045035048501617	0.322353430666308
GO:0050145	nucleoside monophosphate kinase activity	2/335	19/18639	0.105263157894737	5.85671641791045	0.045035048501617	0.322353430666308
GO:0005496	steroid binding	5/335	108/18639	0.0462962962962963	2.57587064676617	0.0454089197997431	0.322353430666308
GO:0003725	double-stranded RNA binding	4/335	75/18639	0.0533333333333333	2.96740298507463	0.0460933755830001	0.323655658984979
GO:0031625	ubiquitin protein ligase binding	10/335	302/18639	0.033112582781457	1.84234456854799	0.0471049964949086	0.327202448771086
GO:0042288	MHC class I protein binding	2/335	20/18639	0.1	5.56388059701493	0.0494580602113359	0.339892626558755
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	11/335	349/18639	0.0315186246418338	1.75365864089296	0.0515724872272435	0.342193756931106
GO:0019199	transmembrane receptor protein kinase activity	4/335	78/18639	0.0512820512820513	2.8532721010333	0.0519223801403186	0.342193756931106
GO:0043495	protein-membrane adaptor activity	3/335	47/18639	0.0638297872340425	3.5514131470308	0.0522304768277606	0.342193756931106
GO:0140597	protein carrier chaperone	7/335	188/18639	0.0372340425531915	2.0716576691013	0.0537594506581755	0.342193756931106
GO:0046332	SMAD binding	4/335	79/18639	0.0506329113924051	2.81715473266578	0.0539507340617366	0.342193756931106
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	2/335	21/18639	0.0952380952380952	5.29893390191898	0.0540305931996483	0.342193756931106
GO:0009931	calcium-dependent protein serine/threonine kinase activity	2/335	21/18639	0.0952380952380952	5.29893390191898	0.0540305931996483	0.342193756931106
GO:0051010	microtubule plus-end binding	2/335	21/18639	0.0952380952380952	5.29893390191898	0.0540305931996483	0.342193756931106
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	3/335	48/18639	0.0625	3.47742537313433	0.0549983289433712	0.344940975703085
GO:0001618	virus receptor activity	4/335	81/18639	0.0493827160493827	2.74759535655058	0.0581346809697027	0.361105806792577
GO:0061133	endopeptidase activator activity	2/335	22/18639	0.0909090909090909	5.05807327001357	0.05874587969529	0.361427031268165
GO:1990782	protein tyrosine kinase binding	5/335	117/18639	0.0427350427350427	2.37772675086108	0.0601046775368916	0.363311911454704
GO:0140272	exogenous protein binding	4/335	82/18639	0.0487804878048781	2.71408809610484	0.0602899438907947	0.363311911454704
GO:0032813	tumor necrosis factor receptor superfamily binding	3/335	50/18639	0.06	3.33832835820896	0.0607394526890218	0.363311911454704
GO:0008017	microtubule binding	9/335	276/18639	0.0326086956521739	1.81430889033095	0.0623640894798594	0.3669699846171
GO:0001540	amyloid-beta binding	4/335	83/18639	0.0481927710843374	2.68138823952527	0.0624871490834071	0.3669699846171
GO:0016493	C-C chemokine receptor activity	2/335	23/18639	0.0869565217391304	4.83815704088254	0.0635973456168591	0.368784448512873
GO:0003712	transcription coregulator activity	14/335	495/18639	0.0282828282828283	1.57362279511533	0.0643571861216044	0.368784448512873
GO:0042578	phosphoric ester hydrolase activity	11/335	363/18639	0.0303030303030303	1.68602442333786	0.0645087348017873	0.368784448512873
GO:0019957	C-C chemokine binding	2/335	24/18639	0.0833333333333333	4.6365671641791	0.0685786058309786	0.385232864059236
GO:0050431	transforming growth factor beta binding	2/335	24/18639	0.0833333333333333	4.6365671641791	0.0685786058309786	0.385232864059236
GO:0003925	G protein activity	3/335	54/18639	0.0555555555555556	3.0910447761194	0.0730177867683205	0.396382271028026
GO:0015485	cholesterol binding	3/335	54/18639	0.0555555555555556	3.0910447761194	0.0730177867683205	0.396382271028026
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	3/335	54/18639	0.0555555555555556	3.0910447761194	0.0730177867683205	0.396382271028026
GO:0017069	snRNA binding	3/335	54/18639	0.0555555555555556	3.0910447761194	0.0730177867683205	0.396382271028026
GO:0140713	histone chaperone activity	6/335	164/18639	0.0365853658536585	2.03556607207863	0.0760313022787166	0.398815041421215
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	4/335	89/18639	0.0449438202247191	2.50062049304042	0.076538201804205	0.398815041421215
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	4/335	89/18639	0.0449438202247191	2.50062049304042	0.076538201804205	0.398815041421215
GO:0003924	GTPase activity	10/335	331/18639	0.0302114803625378	1.68093069396221	0.0767834024343951	0.398815041421215
GO:0001637	G protein-coupled chemoattractant receptor activity	2/335	26/18639	0.0769230769230769	4.27990815154994	0.0789058856396618	0.398815041421215
GO:0004950	chemokine receptor activity	2/335	26/18639	0.0769230769230769	4.27990815154994	0.0789058856396618	0.398815041421215
GO:0019865	immunoglobulin binding	2/335	26/18639	0.0769230769230769	4.27990815154994	0.0789058856396618	0.398815041421215
GO:0030247	polysaccharide binding	2/335	26/18639	0.0769230769230769	4.27990815154994	0.0789058856396618	0.398815041421215
GO:0140793	histone H2AXY142 phosphatase activity	4/335	90/18639	0.0444444444444444	2.47283582089552	0.0790221753899621	0.398815041421215
GO:0004601	peroxidase activity	3/335	57/18639	0.0526315789473684	2.92835820895522	0.0828919372868061	0.415102259591293
GO:0043178	alcohol binding	4/335	92/18639	0.0434782608695652	2.41907852044127	0.0841091870966792	0.415412709019363
GO:0005044	scavenger receptor activity	2/335	27/18639	0.0740740740740741	4.12139303482587	0.0842400385163105	0.415412709019363
GO:0015631	tubulin binding	11/335	385/18639	0.0285714285714286	1.58968017057569	0.0887997983439286	0.432799133900713
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	3/335	59/18639	0.0508474576271186	2.82909182899064	0.0897756717379187	0.432799133900713
GO:0031593	polyubiquitin modification-dependent protein binding	3/335	59/18639	0.0508474576271186	2.82909182899064	0.0897756717379187	0.432799133900713
GO:0004714	transmembrane receptor protein tyrosine kinase activity	3/335	60/18639	0.05	2.78194029850746	0.093304495792554	0.446479290977703
GO:0051087	protein-folding chaperone binding	5/335	134/18639	0.0373134328358209	2.07607484963243	0.0943682172809134	0.448249032084339
GO:0004721	phosphoprotein phosphatase activity	6/335	175/18639	0.0342857142857143	1.90761620469083	0.0964346172355953	0.454720895870033
GO:0004725	protein tyrosine phosphatase activity	4/335	98/18639	0.0408163265306122	2.27097167225099	0.10029687396224	0.458828055600204
GO:0001968	fibronectin binding	2/335	30/18639	0.0666666666666667	3.70925373134328	0.100856941014286	0.458828055600204
GO:0033612	receptor serine/threonine kinase binding	2/335	30/18639	0.0666666666666667	3.70925373134328	0.100856941014286	0.458828055600204
GO:0048019	receptor antagonist activity	2/335	30/18639	0.0666666666666667	3.70925373134328	0.100856941014286	0.458828055600204
GO:0070566	adenylyltransferase activity	2/335	30/18639	0.0666666666666667	3.70925373134328	0.100856941014286	0.458828055600204
GO:0030295	protein kinase activator activity	5/335	139/18639	0.0359712230215827	2.00139589820681	0.106006569344705	0.476438399753631
GO:0005164	tumor necrosis factor receptor binding	2/335	31/18639	0.0645161290322581	3.58960038517092	0.106582901810235	0.476438399753631
GO:0019001	guanyl nucleotide binding	11/335	400/18639	0.0275	1.5300671641791	0.108190567310166	0.476438399753631
GO:0032561	guanyl ribonucleotide binding	11/335	400/18639	0.0275	1.5300671641791	0.108190567310166	0.476438399753631
GO:0004713	protein tyrosine kinase activity	5/335	140/18639	0.0357142857142857	1.98710021321962	0.108415549169944	0.476438399753631
GO:0038024	cargo receptor activity	3/335	65/18639	0.0461538461538462	2.56794489092997	0.111772022618502	0.480837236613316
GO:0051059	NF-kappaB binding	2/335	32/18639	0.0625	3.47742537313433	0.112393843233144	0.480837236613316
GO:0071813	lipoprotein particle binding	2/335	32/18639	0.0625	3.47742537313433	0.112393843233144	0.480837236613316
GO:0071814	protein-lipid complex binding	2/335	32/18639	0.0625	3.47742537313433	0.112393843233144	0.480837236613316
GO:0061134	peptidase regulator activity	7/335	226/18639	0.0309734513274336	1.72332584863294	0.114051516246675	0.484718944048369
GO:0019903	protein phosphatase binding	5/335	144/18639	0.0347222222222222	1.93190298507463	0.118315369972185	0.499553784327005
GO:0016791	phosphatase activity	8/335	273/18639	0.0293040293040293	1.63044120059045	0.120327263945875	0.504749431876851
GO:0002039	p53 binding	3/335	69/18639	0.0434782608695652	2.41907852044127	0.127462892919105	0.529348132785919
GO:0019209	kinase activator activity	5/335	148/18639	0.0337837837837838	1.87968939088342	0.128626139763408	0.529348132785919
GO:0000175	3'-5'-RNA exonuclease activity	2/335	35/18639	0.0571428571428571	3.17936034115139	0.130288472311085	0.529348132785919
GO:0005154	epidermal growth factor receptor binding	2/335	35/18639	0.0571428571428571	3.17936034115139	0.130288472311085	0.529348132785919
GO:0061631	ubiquitin conjugating enzyme activity	2/335	35/18639	0.0571428571428571	3.17936034115139	0.130288472311085	0.529348132785919
GO:0030246	carbohydrate binding	8/335	280/18639	0.0285714285714286	1.58968017057569	0.133297244621651	0.537790859645639
GO:0000510	H3-H4 histone complex chaperone activity	5/335	151/18639	0.033112582781457	1.84234456854799	0.136619198699133	0.537790859645639
GO:0140584	chromatin extrusion motor activity	5/335	151/18639	0.033112582781457	1.84234456854799	0.136619198699133	0.537790859645639
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	5/335	151/18639	0.033112582781457	1.84234456854799	0.136619198699133	0.537790859645639
GO:0140849	ATP-dependent H2AZ histone chaperone activity	5/335	151/18639	0.033112582781457	1.84234456854799	0.136619198699133	0.537790859645639
GO:0015616	DNA translocase activity	5/335	152/18639	0.0328947368421053	1.83022388059702	0.139331644736433	0.537790859645639
GO:0140674	ATP-dependent histone chaperone activity	5/335	152/18639	0.0328947368421053	1.83022388059702	0.139331644736433	0.537790859645639
GO:0003774	cytoskeletal motor activity	5/335	153/18639	0.0326797385620915	1.81826163301141	0.142067673330041	0.537790859645639
GO:0061775	cohesin loader activity	5/335	153/18639	0.0326797385620915	1.81826163301141	0.142067673330041	0.537790859645639
GO:0042805	actinin binding	2/335	37/18639	0.0540540540540541	3.00750302541347	0.142557493008346	0.537790859645639
GO:0005525	GTP binding	10/335	378/18639	0.0264550264550265	1.47192608386638	0.145138017231672	0.537790859645639
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	2/335	38/18639	0.0526315789473684	2.92835820895522	0.148780835815549	0.537790859645639
GO:0043531	ADP binding	2/335	38/18639	0.0526315789473684	2.92835820895522	0.148780835815549	0.537790859645639
GO:0019003	GDP binding	3/335	75/18639	0.04	2.22555223880597	0.152345339720412	0.537790859645639
GO:0000217	DNA secondary structure binding	2/335	39/18639	0.0512820512820513	2.8532721010333	0.155057954022322	0.537790859645639
GO:0016776	phosphotransferase activity, phosphate group as acceptor	2/335	39/18639	0.0512820512820513	2.8532721010333	0.155057954022322	0.537790859645639
GO:0140658	ATP-dependent chromatin remodeler activity	5/335	158/18639	0.0316455696202532	1.76072170791612	0.156091429507273	0.537790859645639
GO:0042393	histone binding	7/335	247/18639	0.0283400809716599	1.57680826636051	0.158145711416029	0.537790859645639
GO:0003724	RNA helicase activity	3/335	77/18639	0.038961038961039	2.16774568714867	0.160959327358342	0.537790859645639
GO:0004532	RNA exonuclease activity	2/335	40/18639	0.05	2.78194029850746	0.161384921499745	0.537790859645639
GO:0015036	disulfide oxidoreductase activity	2/335	40/18639	0.05	2.78194029850746	0.161384921499745	0.537790859645639
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	2/335	40/18639	0.05	2.78194029850746	0.161384921499745	0.537790859645639
GO:0071855	neuropeptide receptor binding	2/335	40/18639	0.05	2.78194029850746	0.161384921499745	0.537790859645639
GO:0003689	DNA clamp loader activity	5/335	160/18639	0.03125	1.73871268656716	0.161855716726005	0.537790859645639
GO:0099106	ion channel regulator activity	5/335	160/18639	0.03125	1.73871268656716	0.161855716726005	0.537790859645639
GO:0001094	TFIID-class transcription factor complex binding	1/335	10/18639	0.1	5.56388059701493	0.165906395315645	0.537790859645639
GO:0003680	minor groove of adenine-thymine-rich DNA binding	1/335	10/18639	0.1	5.56388059701493	0.165906395315645	0.537790859645639
GO:0005522	profilin binding	1/335	10/18639	0.1	5.56388059701493	0.165906395315645	0.537790859645639
GO:0008297	single-stranded DNA exodeoxyribonuclease activity	1/335	10/18639	0.1	5.56388059701493	0.165906395315645	0.537790859645639
GO:0019911	structural constituent of myelin sheath	1/335	10/18639	0.1	5.56388059701493	0.165906395315645	0.537790859645639
GO:0030957	Tat protein binding	1/335	10/18639	0.1	5.56388059701493	0.165906395315645	0.537790859645639
GO:0031996	thioesterase binding	1/335	10/18639	0.1	5.56388059701493	0.165906395315645	0.537790859645639
GO:0035374	chondroitin sulfate binding	1/335	10/18639	0.1	5.56388059701493	0.165906395315645	0.537790859645639
GO:0042975	peroxisome proliferator activated receptor binding	1/335	10/18639	0.1	5.56388059701493	0.165906395315645	0.537790859645639
GO:0045322	unmethylated CpG binding	1/335	10/18639	0.1	5.56388059701493	0.165906395315645	0.537790859645639
GO:0140999	histone H3K4 trimethyltransferase activity	1/335	10/18639	0.1	5.56388059701493	0.165906395315645	0.537790859645639
GO:0061650	ubiquitin-like protein conjugating enzyme activity	2/335	41/18639	0.0487804878048781	2.71408809610484	0.167757935099461	0.537790859645639
GO:0008186	ATP-dependent activity, acting on RNA	3/335	79/18639	0.0379746835443038	2.11286604949934	0.169716992267537	0.537790859645639
GO:0051082	unfolded protein binding	4/335	121/18639	0.0330578512396694	1.83929937091402	0.173695224849196	0.537790859645639
GO:0030971	receptor tyrosine kinase binding	3/335	81/18639	0.037037037037037	2.06069651741294	0.178608684854114	0.537790859645639
GO:0003713	transcription coactivator activity	7/335	256/18639	0.02734375	1.52137360074627	0.179123813021628	0.537790859645639
GO:0048156	tau protein binding	2/335	43/18639	0.0465116279069767	2.58785144047206	0.180627484266184	0.537790859645639
GO:0002162	dystroglycan binding	1/335	11/18639	0.0909090909090909	5.05807327001357	0.18090566299342	0.537790859645639
GO:0005114	type II transforming growth factor beta receptor binding	1/335	11/18639	0.0909090909090909	5.05807327001357	0.18090566299342	0.537790859645639
GO:0008046	axon guidance receptor activity	1/335	11/18639	0.0909090909090909	5.05807327001357	0.18090566299342	0.537790859645639
GO:0008172	S-methyltransferase activity	1/335	11/18639	0.0909090909090909	5.05807327001357	0.18090566299342	0.537790859645639
GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	1/335	11/18639	0.0909090909090909	5.05807327001357	0.18090566299342	0.537790859645639
GO:0034056	estrogen response element binding	1/335	11/18639	0.0909090909090909	5.05807327001357	0.18090566299342	0.537790859645639
GO:0034511	U3 snoRNA binding	1/335	11/18639	0.0909090909090909	5.05807327001357	0.18090566299342	0.537790859645639
GO:0045294	alpha-catenin binding	1/335	11/18639	0.0909090909090909	5.05807327001357	0.18090566299342	0.537790859645639
GO:0050998	nitric-oxide synthase binding	1/335	11/18639	0.0909090909090909	5.05807327001357	0.18090566299342	0.537790859645639
GO:0097493	structural molecule activity conferring elasticity	1/335	11/18639	0.0909090909090909	5.05807327001357	0.18090566299342	0.537790859645639
GO:0140031	phosphorylation-dependent protein binding	1/335	11/18639	0.0909090909090909	5.05807327001357	0.18090566299342	0.537790859645639
GO:1990948	ubiquitin ligase inhibitor activity	1/335	11/18639	0.0909090909090909	5.05807327001357	0.18090566299342	0.537790859645639
GO:0016247	channel regulator activity	5/335	168/18639	0.0297619047619048	1.65591684434968	0.18573489437225	0.537790859645639
GO:0001046	core promoter sequence-specific DNA binding	2/335	44/18639	0.0454545454545455	2.52903663500678	0.187117000627107	0.537790859645639
GO:0019205	nucleobase-containing compound kinase activity	2/335	44/18639	0.0454545454545455	2.52903663500678	0.187117000627107	0.537790859645639
GO:0030547	signaling receptor inhibitor activity	2/335	44/18639	0.0454545454545455	2.52903663500678	0.187117000627107	0.537790859645639
GO:0141108	transporter regulator activity	5/335	170/18639	0.0294117647058824	1.63643546971027	0.191897199029878	0.537790859645639
GO:0004860	protein kinase inhibitor activity	3/335	84/18639	0.0357142857142857	1.98710021321962	0.19217665717532	0.537790859645639
GO:0004715	non-membrane spanning protein tyrosine kinase activity	2/335	45/18639	0.0444444444444444	2.47283582089552	0.193638518792731	0.537790859645639
GO:0008009	chemokine activity	2/335	45/18639	0.0444444444444444	2.47283582089552	0.193638518792731	0.537790859645639
GO:0046915	transition metal ion transmembrane transporter activity	2/335	45/18639	0.0444444444444444	2.47283582089552	0.193638518792731	0.537790859645639
GO:0016840	carbon-nitrogen lyase activity	1/335	12/18639	0.0833333333333333	4.6365671641791	0.19563599383394	0.537790859645639
GO:0035251	UDP-glucosyltransferase activity	1/335	12/18639	0.0833333333333333	4.6365671641791	0.19563599383394	0.537790859645639
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	1/335	12/18639	0.0833333333333333	4.6365671641791	0.19563599383394	0.537790859645639
GO:0070008	serine-type exopeptidase activity	1/335	12/18639	0.0833333333333333	4.6365671641791	0.19563599383394	0.537790859645639
GO:0070679	inositol 1,4,5 trisphosphate binding	1/335	12/18639	0.0833333333333333	4.6365671641791	0.19563599383394	0.537790859645639
GO:0097371	MDM2/MDM4 family protein binding	1/335	12/18639	0.0833333333333333	4.6365671641791	0.19563599383394	0.537790859645639
GO:0097677	STAT family protein binding	1/335	12/18639	0.0833333333333333	4.6365671641791	0.19563599383394	0.537790859645639
GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	1/335	12/18639	0.0833333333333333	4.6365671641791	0.19563599383394	0.537790859645639
GO:0140822	NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity	1/335	12/18639	0.0833333333333333	4.6365671641791	0.19563599383394	0.537790859645639
GO:0140844	NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity	1/335	12/18639	0.0833333333333333	4.6365671641791	0.19563599383394	0.537790859645639
GO:0140867	NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity	1/335	12/18639	0.0833333333333333	4.6365671641791	0.19563599383394	0.537790859645639
GO:1990247	N6-methyladenosine-containing RNA reader activity	1/335	12/18639	0.0833333333333333	4.6365671641791	0.19563599383394	0.537790859645639
GO:1990459	transferrin receptor binding	1/335	12/18639	0.0833333333333333	4.6365671641791	0.19563599383394	0.537790859645639
GO:0030276	clathrin binding	2/335	46/18639	0.0434782608695652	2.41907852044127	0.200188804985992	0.542904073675833
GO:0030291	protein serine/threonine kinase inhibitor activity	2/335	46/18639	0.0434782608695652	2.41907852044127	0.200188804985992	0.542904073675833
GO:0140030	modification-dependent protein binding	5/335	173/18639	0.0289017341040462	1.60805797601587	0.201274184567885	0.542904073675833
GO:0001784	phosphotyrosine residue binding	2/335	47/18639	0.0425531914893617	2.3676087646872	0.206764730681914	0.542904073675833
GO:0140359	ABC-type transporter activity	2/335	47/18639	0.0425531914893617	2.3676087646872	0.206764730681914	0.542904073675833
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	7/335	268/18639	0.0261194029850746	1.4532523947427	0.208797430326549	0.542904073675833
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	1/335	13/18639	0.0769230769230769	4.27990815154994	0.210102195694982	0.542904073675833
GO:0008253	5'-nucleotidase activity	1/335	13/18639	0.0769230769230769	4.27990815154994	0.210102195694982	0.542904073675833
GO:0017154	semaphorin receptor activity	1/335	13/18639	0.0769230769230769	4.27990815154994	0.210102195694982	0.542904073675833
GO:0031432	titin binding	1/335	13/18639	0.0769230769230769	4.27990815154994	0.210102195694982	0.542904073675833
GO:0039706	co-receptor binding	1/335	13/18639	0.0769230769230769	4.27990815154994	0.210102195694982	0.542904073675833
GO:0043560	insulin receptor substrate binding	1/335	13/18639	0.0769230769230769	4.27990815154994	0.210102195694982	0.542904073675833
GO:0070700	BMP receptor binding	1/335	13/18639	0.0769230769230769	4.27990815154994	0.210102195694982	0.542904073675833
GO:0140410	monoatomic cation:bicarbonate symporter activity	1/335	13/18639	0.0769230769230769	4.27990815154994	0.210102195694982	0.542904073675833
GO:0140806	NAD+-protein-aspartate ADP-ribosyltransferase activity	1/335	13/18639	0.0769230769230769	4.27990815154994	0.210102195694982	0.542904073675833
GO:0001222	transcription corepressor binding	2/335	49/18639	0.0408163265306122	2.27097167225099	0.219981496487552	0.56173947790288
GO:0019210	kinase inhibitor activity	3/335	90/18639	0.0333333333333333	1.85462686567164	0.220026633591013	0.56173947790288
GO:0004705	JUN kinase activity	1/335	14/18639	0.0714285714285714	3.97420042643923	0.224308990736439	0.56173947790288
GO:0008494	translation activator activity	1/335	14/18639	0.0714285714285714	3.97420042643923	0.224308990736439	0.56173947790288
GO:0008559	ABC-type xenobiotic transporter activity	1/335	14/18639	0.0714285714285714	3.97420042643923	0.224308990736439	0.56173947790288
GO:0044548	S100 protein binding	1/335	14/18639	0.0714285714285714	3.97420042643923	0.224308990736439	0.56173947790288
GO:0061665	SUMO ligase activity	1/335	14/18639	0.0714285714285714	3.97420042643923	0.224308990736439	0.56173947790288
GO:0005006	epidermal growth factor receptor activity	2/335	50/18639	0.04	2.22555223880597	0.226616581645824	0.56173947790288
GO:0048020	CCR chemokine receptor binding	2/335	50/18639	0.04	2.22555223880597	0.226616581645824	0.56173947790288
GO:0140789	histone phosphatase activity	4/335	136/18639	0.0294117647058824	1.63643546971027	0.229069876776349	0.56173947790288
GO:0005010	insulin-like growth factor receptor activity	2/335	51/18639	0.0392156862745098	2.1819139596137	0.233265791275472	0.56173947790288
GO:0001217	DNA-binding transcription repressor activity	7/335	278/18639	0.0251798561151079	1.40097712874477	0.234832766366153	0.56173947790288
GO:0061135	endopeptidase regulator activity	5/335	184/18639	0.0271739130434783	1.51192407527579	0.236885967878931	0.56173947790288
GO:0004129	cytochrome-c oxidase activity	1/335	15/18639	0.0666666666666667	3.70925373134328	0.238261016943327	0.56173947790288
GO:0005041	low-density lipoprotein particle receptor activity	1/335	15/18639	0.0666666666666667	3.70925373134328	0.238261016943327	0.56173947790288
GO:0005523	tropomyosin binding	1/335	15/18639	0.0666666666666667	3.70925373134328	0.238261016943327	0.56173947790288
GO:0008252	nucleotidase activity	1/335	15/18639	0.0666666666666667	3.70925373134328	0.238261016943327	0.56173947790288
GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	1/335	15/18639	0.0666666666666667	3.70925373134328	0.238261016943327	0.56173947790288
GO:0030553	cGMP binding	1/335	15/18639	0.0666666666666667	3.70925373134328	0.238261016943327	0.56173947790288
GO:0031005	filamin binding	1/335	15/18639	0.0666666666666667	3.70925373134328	0.238261016943327	0.56173947790288
GO:0047372	monoacylglycerol lipase activity	1/335	15/18639	0.0666666666666667	3.70925373134328	0.238261016943327	0.56173947790288
GO:0050700	CARD domain binding	1/335	15/18639	0.0666666666666667	3.70925373134328	0.238261016943327	0.56173947790288
GO:0050780	dopamine receptor binding	1/335	15/18639	0.0666666666666667	3.70925373134328	0.238261016943327	0.56173947790288
GO:0055105	ubiquitin-protein transferase inhibitor activity	1/335	15/18639	0.0666666666666667	3.70925373134328	0.238261016943327	0.56173947790288
GO:0005544	calcium-dependent phospholipid binding	2/335	53/18639	0.0377358490566038	2.09957758377922	0.246596106547726	0.565166624776689
GO:0140296	general transcription initiation factor binding	2/335	53/18639	0.0377358490566038	2.09957758377922	0.246596106547726	0.565166624776689
GO:0008234	cysteine-type peptidase activity	5/335	187/18639	0.0267379679144385	1.48766860882752	0.246892031559664	0.565166624776689
GO:0004896	cytokine receptor activity	3/335	96/18639	0.03125	1.73871268656716	0.248626014362937	0.565166624776689
GO:0004707	MAP kinase activity	1/335	16/18639	0.0625	3.47742537313433	0.251962829621805	0.565166624776689
GO:0005024	transforming growth factor beta receptor activity	1/335	16/18639	0.0625	3.47742537313433	0.251962829621805	0.565166624776689
GO:0005159	insulin-like growth factor receptor binding	1/335	16/18639	0.0625	3.47742537313433	0.251962829621805	0.565166624776689
GO:0008296	3'-5'-DNA exonuclease activity	1/335	16/18639	0.0625	3.47742537313433	0.251962829621805	0.565166624776689
GO:0016675	oxidoreductase activity, acting on a heme group of donors	1/335	16/18639	0.0625	3.47742537313433	0.251962829621805	0.565166624776689
GO:0017070	U6 snRNA binding	1/335	16/18639	0.0625	3.47742537313433	0.251962829621805	0.565166624776689
GO:0022858	alanine transmembrane transporter activity	1/335	16/18639	0.0625	3.47742537313433	0.251962829621805	0.565166624776689
GO:0031435	mitogen-activated protein kinase kinase kinase binding	1/335	16/18639	0.0625	3.47742537313433	0.251962829621805	0.565166624776689
GO:0034450	ubiquitin-ubiquitin ligase activity	1/335	16/18639	0.0625	3.47742537313433	0.251962829621805	0.565166624776689
GO:0070411	I-SMAD binding	1/335	16/18639	0.0625	3.47742537313433	0.251962829621805	0.565166624776689
GO:0004550	nucleoside diphosphate kinase activity	1/335	17/18639	0.0588235294117647	3.27287093942054	0.265418902868688	0.579258821801259
GO:0005092	GDP-dissociation inhibitor activity	1/335	17/18639	0.0588235294117647	3.27287093942054	0.265418902868688	0.579258821801259
GO:0008429	phosphatidylethanolamine binding	1/335	17/18639	0.0588235294117647	3.27287093942054	0.265418902868688	0.579258821801259
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	1/335	17/18639	0.0588235294117647	3.27287093942054	0.265418902868688	0.579258821801259
GO:0015278	intracellularly gated calcium channel activity	1/335	17/18639	0.0588235294117647	3.27287093942054	0.265418902868688	0.579258821801259
GO:0031489	myosin V binding	1/335	17/18639	0.0588235294117647	3.27287093942054	0.265418902868688	0.579258821801259
GO:0051787	misfolded protein binding	1/335	17/18639	0.0588235294117647	3.27287093942054	0.265418902868688	0.579258821801259
GO:1990226	histone methyltransferase binding	1/335	17/18639	0.0588235294117647	3.27287093942054	0.265418902868688	0.579258821801259
GO:0043130	ubiquitin binding	3/335	100/18639	0.03	1.66916417910448	0.267994249862013	0.582910051888419
GO:0005539	glycosaminoglycan binding	6/335	242/18639	0.0247933884297521	1.37947452818552	0.269855595680991	0.584733493921792
GO:0008236	serine-type peptidase activity	5/335	194/18639	0.0257731958762887	1.43398984459148	0.270642901985473	0.584733493921792
GO:0008238	exopeptidase activity	3/335	102/18639	0.0294117647058824	1.63643546971027	0.277744587917545	0.588226554364815
GO:0000400	four-way junction DNA binding	1/335	18/18639	0.0555555555555556	3.0910447761194	0.278633631014912	0.588226554364815
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	1/335	18/18639	0.0555555555555556	3.0910447761194	0.278633631014912	0.588226554364815
GO:0015172	acidic amino acid transmembrane transporter activity	1/335	18/18639	0.0555555555555556	3.0910447761194	0.278633631014912	0.588226554364815
GO:0017128	phospholipid scramblase activity	1/335	18/18639	0.0555555555555556	3.0910447761194	0.278633631014912	0.588226554364815
GO:0030228	lipoprotein particle receptor activity	1/335	18/18639	0.0555555555555556	3.0910447761194	0.278633631014912	0.588226554364815
GO:0098641	cadherin binding involved in cell-cell adhesion	1/335	18/18639	0.0555555555555556	3.0910447761194	0.278633631014912	0.588226554364815
GO:0008408	3'-5' exonuclease activity	2/335	58/18639	0.0344827586206897	1.91857951621204	0.279994860586198	0.589174853220468
GO:0017171	serine hydrolase activity	5/335	198/18639	0.0252525252525253	1.40502035278155	0.284432362222878	0.596569175311621
GO:0001786	phosphatidylserine binding	2/335	59/18639	0.0338983050847458	1.88606121932709	0.286669218089646	0.597381660922294
GO:0045309	protein phosphorylated amino acid binding	2/335	59/18639	0.0338983050847458	1.88606121932709	0.286669218089646	0.597381660922294
GO:0008301	DNA binding, bending	1/335	19/18639	0.0526315789473684	2.92835820895522	0.291611330043429	0.598034664152555
GO:0008574	plus-end-directed microtubule motor activity	1/335	19/18639	0.0526315789473684	2.92835820895522	0.291611330043429	0.598034664152555
GO:0042800	histone H3K4 methyltransferase activity	1/335	19/18639	0.0526315789473684	2.92835820895522	0.291611330043429	0.598034664152555
GO:0043395	heparan sulfate proteoglycan binding	1/335	19/18639	0.0526315789473684	2.92835820895522	0.291611330043429	0.598034664152555
GO:0046527	glucosyltransferase activity	1/335	19/18639	0.0526315789473684	2.92835820895522	0.291611330043429	0.598034664152555
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	2/335	60/18639	0.0333333333333333	1.85462686567164	0.293336967134374	0.59966987585065
GO:0015026	coreceptor activity	2/335	61/18639	0.0327868852459016	1.82422314656227	0.29999619414957	0.606833735747983
GO:0004386	helicase activity	4/335	155/18639	0.0258064516129032	1.43584015406837	0.304251386981677	0.606833735747983
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	1/335	20/18639	0.05	2.78194029850746	0.30435623898196	0.606833735747983
GO:0015095	magnesium ion transmembrane transporter activity	1/335	20/18639	0.05	2.78194029850746	0.30435623898196	0.606833735747983
GO:0016004	phospholipase activator activity	1/335	20/18639	0.05	2.78194029850746	0.30435623898196	0.606833735747983
GO:0016505	peptidase activator activity involved in apoptotic process	1/335	20/18639	0.05	2.78194029850746	0.30435623898196	0.606833735747983
GO:0031418	L-ascorbic acid binding	1/335	20/18639	0.05	2.78194029850746	0.30435623898196	0.606833735747983
GO:0061608	nuclear import signal receptor activity	1/335	20/18639	0.05	2.78194029850746	0.30435623898196	0.606833735747983
GO:0005507	copper ion binding	2/335	63/18639	0.0317460317460317	1.76631130063966	0.313281778454913	0.622187382191838
GO:0005123	death receptor binding	1/335	21/18639	0.0476190476190476	2.64946695095949	0.316872521271076	0.622187382191838
GO:0015125	bile acid transmembrane transporter activity	1/335	21/18639	0.0476190476190476	2.64946695095949	0.316872521271076	0.622187382191838
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	1/335	21/18639	0.0476190476190476	2.64946695095949	0.316872521271076	0.622187382191838
GO:0070182	DNA polymerase binding	1/335	21/18639	0.0476190476190476	2.64946695095949	0.316872521271076	0.622187382191838
GO:0008094	ATP-dependent activity, acting on DNA	5/335	210/18639	0.0238095238095238	1.32473347547974	0.32649583158945	0.625113811823948
GO:0005200	structural constituent of cytoskeleton	3/335	112/18639	0.0267857142857143	1.49032515991471	0.326857529601381	0.625113811823948
GO:0031683	G-protein beta/gamma-subunit complex binding	1/335	22/18639	0.0454545454545455	2.52903663500678	0.329164266108018	0.625113811823948
GO:0033691	sialic acid binding	1/335	22/18639	0.0454545454545455	2.52903663500678	0.329164266108018	0.625113811823948
GO:0034062	5'-3' RNA polymerase activity	1/335	22/18639	0.0454545454545455	2.52903663500678	0.329164266108018	0.625113811823948
GO:0097747	RNA polymerase activity	1/335	22/18639	0.0454545454545455	2.52903663500678	0.329164266108018	0.625113811823948
GO:0140517	protein-RNA adaptor activity	1/335	22/18639	0.0454545454545455	2.52903663500678	0.329164266108018	0.625113811823948
GO:0008083	growth factor activity	4/335	162/18639	0.0246913580246914	1.37379767827529	0.332686952413835	0.625113811823948
GO:0004857	enzyme inhibitor activity	9/335	416/18639	0.0216346153846154	1.20372416762342	0.333336370112471	0.625113811823948
GO:0016887	ATP hydrolysis activity	9/335	417/18639	0.0215827338129496	1.20083753892408	0.335848975545648	0.625113811823948
GO:0005283	amino acid:sodium symporter activity	1/335	23/18639	0.0434782608695652	2.41907852044127	0.341235489766707	0.625113811823948
GO:0043274	phospholipase binding	1/335	23/18639	0.0434782608695652	2.41907852044127	0.341235489766707	0.625113811823948
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	1/335	23/18639	0.0434782608695652	2.41907852044127	0.341235489766707	0.625113811823948
GO:0070577	lysine-acetylated histone binding	1/335	23/18639	0.0434782608695652	2.41907852044127	0.341235489766707	0.625113811823948
GO:0099186	structural constituent of postsynapse	1/335	23/18639	0.0434782608695652	2.41907852044127	0.341235489766707	0.625113811823948
GO:0001221	transcription coregulator binding	3/335	115/18639	0.0260869565217391	1.45144711226476	0.341623715250261	0.625113811823948
GO:0017124	SH3 domain binding	3/335	115/18639	0.0260869565217391	1.45144711226476	0.341623715250261	0.625113811823948
GO:0035401	histone H3Y41 kinase activity	3/335	115/18639	0.0260869565217391	1.45144711226476	0.341623715250261	0.625113811823948
GO:0140801	histone H2AXY142 kinase activity	3/335	115/18639	0.0260869565217391	1.45144711226476	0.341623715250261	0.625113811823948
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	2/335	68/18639	0.0294117647058824	1.63643546971027	0.346225763336742	0.625113811823948
GO:0030145	manganese ion binding	2/335	68/18639	0.0294117647058824	1.63643546971027	0.346225763336742	0.625113811823948
GO:1990841	promoter-specific chromatin binding	2/335	68/18639	0.0294117647058824	1.63643546971027	0.346225763336742	0.625113811823948
GO:0009055	electron transfer activity	3/335	116/18639	0.0258620689655172	1.43893463715903	0.346541483746734	0.625113811823948
GO:0016757	glycosyltransferase activity	6/335	267/18639	0.0224719101123595	1.25031024652021	0.34817743742565	0.625113811823948
GO:0015399	primary active transmembrane transporter activity	4/335	166/18639	0.0240963855421687	1.34069411976263	0.349001853479209	0.625113811823948
GO:0001091	RNA polymerase II general transcription initiation factor binding	1/335	24/18639	0.0416666666666667	2.31828358208955	0.353090136894347	0.625113811823948
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	1/335	24/18639	0.0416666666666667	2.31828358208955	0.353090136894347	0.625113811823948
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	1/335	24/18639	0.0416666666666667	2.31828358208955	0.353090136894347	0.625113811823948
GO:0004622	lysophospholipase activity	1/335	24/18639	0.0416666666666667	2.31828358208955	0.353090136894347	0.625113811823948
GO:0030552	cAMP binding	1/335	24/18639	0.0416666666666667	2.31828358208955	0.353090136894347	0.625113811823948
GO:0060229	lipase activator activity	1/335	24/18639	0.0416666666666667	2.31828358208955	0.353090136894347	0.625113811823948
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	1/335	24/18639	0.0416666666666667	2.31828358208955	0.353090136894347	0.625113811823948
GO:0140033	acetylation-dependent protein binding	1/335	24/18639	0.0416666666666667	2.31828358208955	0.353090136894347	0.625113811823948
GO:0000030	mannosyltransferase activity	1/335	25/18639	0.04	2.22555223880597	0.364732081785048	0.625113811823948
GO:0001848	complement binding	1/335	25/18639	0.04	2.22555223880597	0.364732081785048	0.625113811823948
GO:0003707	nuclear steroid receptor activity	1/335	25/18639	0.04	2.22555223880597	0.364732081785048	0.625113811823948
GO:0008139	nuclear localization sequence binding	1/335	25/18639	0.04	2.22555223880597	0.364732081785048	0.625113811823948
GO:0015296	monoatomic anion:monoatomic cation symporter activity	1/335	25/18639	0.04	2.22555223880597	0.364732081785048	0.625113811823948
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	1/335	25/18639	0.04	2.22555223880597	0.364732081785048	0.625113811823948
GO:0017025	TBP-class protein binding	1/335	25/18639	0.04	2.22555223880597	0.364732081785048	0.625113811823948
GO:0019706	protein-cysteine S-palmitoyltransferase activity	1/335	25/18639	0.04	2.22555223880597	0.364732081785048	0.625113811823948
GO:0019707	protein-cysteine S-acyltransferase activity	1/335	25/18639	0.04	2.22555223880597	0.364732081785048	0.625113811823948
GO:0042974	nuclear retinoic acid receptor binding	1/335	25/18639	0.04	2.22555223880597	0.364732081785048	0.625113811823948
GO:0032182	ubiquitin-like protein binding	3/335	120/18639	0.025	1.39097014925373	0.366171100767536	0.625113811823948
GO:0003697	single-stranded DNA binding	3/335	121/18639	0.0247933884297521	1.37947452818552	0.371064555240036	0.625113811823948
GO:0004540	RNA nuclease activity	3/335	121/18639	0.0247933884297521	1.37947452818552	0.371064555240036	0.625113811823948
GO:0042379	chemokine receptor binding	2/335	72/18639	0.0277777777777778	1.5455223880597	0.372204858810906	0.625113811823948
GO:0008201	heparin binding	4/335	172/18639	0.0232558139534884	1.29392572023603	0.373484667303804	0.625113811823948
GO:0005126	cytokine receptor binding	6/335	275/18639	0.0218181818181818	1.21393758480326	0.373768195268061	0.625113811823948
GO:1901681	sulfur compound binding	6/335	275/18639	0.0218181818181818	1.21393758480326	0.373768195268061	0.625113811823948
GO:0004112	cyclic-nucleotide phosphodiesterase activity	1/335	26/18639	0.0384615384615385	2.13995407577497	0.376165129630864	0.625113811823948
GO:0004435	phosphatidylinositol phospholipase C activity	1/335	26/18639	0.0384615384615385	2.13995407577497	0.376165129630864	0.625113811823948
GO:0004529	DNA exonuclease activity	1/335	26/18639	0.0384615384615385	2.13995407577497	0.376165129630864	0.625113811823948
GO:0005160	transforming growth factor beta receptor binding	1/335	26/18639	0.0384615384615385	2.13995407577497	0.376165129630864	0.625113811823948
GO:0043548	phosphatidylinositol 3-kinase binding	1/335	26/18639	0.0384615384615385	2.13995407577497	0.376165129630864	0.625113811823948
GO:0050681	nuclear androgen receptor binding	1/335	26/18639	0.0384615384615385	2.13995407577497	0.376165129630864	0.625113811823948
GO:0050750	low-density lipoprotein particle receptor binding	1/335	26/18639	0.0384615384615385	2.13995407577497	0.376165129630864	0.625113811823948
GO:0070006	metalloaminopeptidase activity	1/335	26/18639	0.0384615384615385	2.13995407577497	0.376165129630864	0.625113811823948
GO:0070412	R-SMAD binding	1/335	26/18639	0.0384615384615385	2.13995407577497	0.376165129630864	0.625113811823948
GO:0004674	protein serine/threonine kinase activity	9/335	433/18639	0.0207852193995381	1.15646478921788	0.376423022909467	0.625113811823948
GO:0043539	protein serine/threonine kinase activator activity	2/335	73/18639	0.0273972602739726	1.52435084849724	0.378636411099232	0.627177234795138
GO:0001671	ATPase activator activity	1/335	27/18639	0.037037037037037	2.06069651741294	0.387393017750654	0.636783433758073
GO:0005385	zinc ion transmembrane transporter activity	1/335	27/18639	0.037037037037037	2.06069651741294	0.387393017750654	0.636783433758073
GO:0035255	ionotropic glutamate receptor binding	1/335	27/18639	0.037037037037037	2.06069651741294	0.387393017750654	0.636783433758073
GO:0044183	protein folding chaperone	2/335	75/18639	0.0266666666666667	1.48370149253731	0.391415537197062	0.641762530531224
GO:0000287	magnesium ion binding	5/335	230/18639	0.0217391304347826	1.20953926022064	0.397657040181294	0.649093045814183
GO:0005319	lipid transporter activity	4/335	178/18639	0.0224719101123595	1.25031024652021	0.397896046660088	0.649093045814183
GO:0031490	chromatin DNA binding	3/335	128/18639	0.0234375	1.30403451492537	0.405087381970651	0.656015295372106
GO:0003785	actin monomer binding	1/335	29/18639	0.0344827586206897	1.91857951621204	0.409247931942661	0.656015295372106
GO:0004629	phospholipase C activity	1/335	29/18639	0.0344827586206897	1.91857951621204	0.409247931942661	0.656015295372106
GO:0005416	amino acid:monoatomic cation symporter activity	1/335	29/18639	0.0344827586206897	1.91857951621204	0.409247931942661	0.656015295372106
GO:0016417	S-acyltransferase activity	1/335	29/18639	0.0344827586206897	1.91857951621204	0.409247931942661	0.656015295372106
GO:0099604	ligand-gated calcium channel activity	1/335	29/18639	0.0344827586206897	1.91857951621204	0.409247931942661	0.656015295372106
GO:0106222	lncRNA binding	1/335	29/18639	0.0344827586206897	1.91857951621204	0.409247931942661	0.656015295372106
GO:0016835	carbon-oxygen lyase activity	2/335	79/18639	0.0253164556962025	1.40857736633289	0.416609159645017	0.663187870934452
GO:0001965	G-protein alpha-subunit binding	1/335	30/18639	0.0333333333333333	1.85462686567164	0.419882104043639	0.663187870934452
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	1/335	30/18639	0.0333333333333333	1.85462686567164	0.419882104043639	0.663187870934452
GO:0016769	transferase activity, transferring nitrogenous groups	1/335	30/18639	0.0333333333333333	1.85462686567164	0.419882104043639	0.663187870934452
GO:0031624	ubiquitin conjugating enzyme binding	1/335	30/18639	0.0333333333333333	1.85462686567164	0.419882104043639	0.663187870934452
GO:0098918	structural constituent of synapse	1/335	30/18639	0.0333333333333333	1.85462686567164	0.419882104043639	0.663187870934452
GO:0070325	lipoprotein particle receptor binding	1/335	31/18639	0.032258064516129	1.79480019258546	0.430325410784753	0.678024915529147
GO:0015106	bicarbonate transmembrane transporter activity	1/335	32/18639	0.03125	1.73871268656716	0.440581267802547	0.684171872597224
GO:0030515	snoRNA binding	1/335	32/18639	0.03125	1.73871268656716	0.440581267802547	0.684171872597224
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	1/335	32/18639	0.03125	1.73871268656716	0.440581267802547	0.684171872597224
GO:0042910	xenobiotic transmembrane transporter activity	1/335	32/18639	0.03125	1.73871268656716	0.440581267802547	0.684171872597224
GO:0120015	sterol transfer activity	1/335	32/18639	0.03125	1.73871268656716	0.440581267802547	0.684171872597224
GO:0140142	nucleocytoplasmic carrier activity	1/335	32/18639	0.03125	1.73871268656716	0.440581267802547	0.684171872597224
GO:0002020	protease binding	3/335	136/18639	0.0220588235294118	1.2273266022827	0.443282564868957	0.684992605279624
GO:0004175	endopeptidase activity	8/335	405/18639	0.0197530864197531	1.09903814262023	0.443594775689576	0.684992605279624
GO:0004527	exonuclease activity	2/335	84/18639	0.0238095238095238	1.32473347547974	0.447343846250052	0.684992605279624
GO:0051117	ATPase binding	2/335	84/18639	0.0238095238095238	1.32473347547974	0.447343846250052	0.684992605279624
GO:0016922	nuclear receptor binding	3/335	137/18639	0.0218978102189781	1.21836801394487	0.447992319989745	0.684992605279624
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	1/335	33/18639	0.0303030303030303	1.68602442333786	0.450653029789226	0.684992605279624
GO:0030296	protein tyrosine kinase activator activity	1/335	33/18639	0.0303030303030303	1.68602442333786	0.450653029789226	0.684992605279624
GO:0071889	14-3-3 protein binding	1/335	33/18639	0.0303030303030303	1.68602442333786	0.450653029789226	0.684992605279624
GO:0140416	transcription regulator inhibitor activity	1/335	33/18639	0.0303030303030303	1.68602442333786	0.450653029789226	0.684992605279624
GO:0035402	histone H3T11 kinase activity	5/335	247/18639	0.0202429149797571	1.12629161882893	0.457647443591398	0.693292216326834
GO:0050660	flavin adenine dinucleotide binding	2/335	86/18639	0.0232558139534884	1.29392572023603	0.45938258799719	0.693292216326834
GO:0015035	protein-disulfide reductase activity	1/335	34/18639	0.0294117647058824	1.63643546971027	0.460543991576854	0.693292216326834
GO:0030332	cyclin binding	1/335	34/18639	0.0294117647058824	1.63643546971027	0.460543991576854	0.693292216326834
GO:0140996	histone H3 kinase activity	7/335	357/18639	0.0196078431372549	1.09095697980685	0.461479339041082	0.693292216326834
GO:0008081	phosphoric diester hydrolase activity	2/335	87/18639	0.0229885057471264	1.27905301080803	0.465344696363898	0.697477201510622
GO:0035173	histone kinase activity	7/335	360/18639	0.0194444444444444	1.08186567164179	0.470168060064292	0.698291010970887
GO:0005343	organic acid:sodium symporter activity	1/335	35/18639	0.0285714285714286	1.58968017057569	0.470257389202318	0.698291010970887
GO:0016229	steroid dehydrogenase activity	1/335	35/18639	0.0285714285714286	1.58968017057569	0.470257389202318	0.698291010970887
GO:0043015	gamma-tubulin binding	1/335	35/18639	0.0285714285714286	1.58968017057569	0.470257389202318	0.698291010970887
GO:0020037	heme binding	3/335	142/18639	0.0211267605633803	1.17546773176372	0.471292385113478	0.698291010970887
GO:0106310	protein serine kinase activity	7/335	361/18639	0.0193905817174515	1.07886881382561	0.473056964944139	0.699301600352205
GO:0003727	single-stranded RNA binding	2/335	89/18639	0.0224719101123595	1.25031024652021	0.477151580042318	0.70124089370113
GO:0004190	aspartic-type endopeptidase activity	1/335	36/18639	0.0277777777777778	1.5455223880597	0.479796400953405	0.70124089370113
GO:0016409	palmitoyltransferase activity	1/335	36/18639	0.0277777777777778	1.5455223880597	0.479796400953405	0.70124089370113
GO:0044390	ubiquitin-like protein conjugating enzyme binding	1/335	36/18639	0.0277777777777778	1.5455223880597	0.479796400953405	0.70124089370113
GO:0055106	ubiquitin-protein transferase regulator activity	1/335	36/18639	0.0277777777777778	1.5455223880597	0.479796400953405	0.70124089370113
GO:0016829	lyase activity	4/335	200/18639	0.02	1.11277611940299	0.485452883274601	0.705357231839341
GO:0072341	modified amino acid binding	2/335	91/18639	0.021978021978022	1.22283090044284	0.488798649337917	0.705357231839341
GO:0022829	wide pore channel activity	1/335	37/18639	0.027027027027027	1.50375151270674	0.489164148396323	0.705357231839341
GO:0030280	structural constituent of skin epidermis	1/335	37/18639	0.027027027027027	1.50375151270674	0.489164148396323	0.705357231839341
GO:0030551	cyclic nucleotide binding	1/335	37/18639	0.027027027027027	1.50375151270674	0.489164148396323	0.705357231839341
GO:0070001	aspartic-type peptidase activity	1/335	37/18639	0.027027027027027	1.50375151270674	0.489164148396323	0.705357231839341
GO:0051219	phosphoprotein binding	2/335	93/18639	0.021505376344086	1.19653346172364	0.500282284243586	0.719782529223512
GO:0016410	N-acyltransferase activity	2/335	94/18639	0.0212765957446809	1.1838043823436	0.505961808737348	0.7250118526524
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	9/335	484/18639	0.0185950413223141	1.03460589613914	0.506161525613363	0.7250118526524
GO:0004867	serine-type endopeptidase inhibitor activity	2/335	95/18639	0.0210526315789474	1.17134328358209	0.511599323418322	0.728496793180333
GO:0005516	calmodulin binding	4/335	207/18639	0.0193236714975845	1.07514600908501	0.512283594766478	0.728496793180333
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	1/335	40/18639	0.025	1.39097014925373	0.516270190784552	0.728496793180333
GO:0030331	nuclear estrogen receptor binding	1/335	40/18639	0.025	1.39097014925373	0.516270190784552	0.728496793180333
GO:0071949	FAD binding	1/335	40/18639	0.025	1.39097014925373	0.516270190784552	0.728496793180333
GO:0140662	ATP-dependent protein folding chaperone	1/335	40/18639	0.025	1.39097014925373	0.516270190784552	0.728496793180333
GO:0046906	tetrapyrrole binding	3/335	152/18639	0.0197368421052632	1.09813432835821	0.516488438508657	0.728496793180333
GO:0030695	GTPase regulator activity	9/335	489/18639	0.0184049079754601	1.02402710374508	0.518573050193885	0.729331217583085
GO:0060589	nucleoside-triphosphatase regulator activity	9/335	490/18639	0.0183673469387755	1.02193725251295	0.521043592061462	0.729331217583085
GO:0001216	DNA-binding transcription activator activity	9/335	491/18639	0.0183299389002037	1.01985591391312	0.523510025310971	0.729331217583085
GO:0001530	lipopolysaccharide binding	1/335	41/18639	0.024390243902439	1.35704404805242	0.524982997176679	0.729331217583085
GO:0008137	NADH dehydrogenase (ubiquinone) activity	1/335	41/18639	0.024390243902439	1.35704404805242	0.524982997176679	0.729331217583085
GO:0015175	neutral L-amino acid transmembrane transporter activity	1/335	41/18639	0.024390243902439	1.35704404805242	0.524982997176679	0.729331217583085
GO:0017080	sodium channel regulator activity	1/335	41/18639	0.024390243902439	1.35704404805242	0.524982997176679	0.729331217583085
GO:0008170	N-methyltransferase activity	2/335	98/18639	0.0204081632653061	1.13548583612549	0.528256653264018	0.730736184172496
GO:0042626	ATPase-coupled transmembrane transporter activity	2/335	98/18639	0.0204081632653061	1.13548583612549	0.528256653264018	0.730736184172496
GO:0019894	kinesin binding	1/335	42/18639	0.0238095238095238	1.32473347547974	0.533539330973099	0.733332782571536
GO:0035198	miRNA binding	1/335	42/18639	0.0238095238095238	1.32473347547974	0.533539330973099	0.733332782571536
GO:0048487	beta-tubulin binding	1/335	42/18639	0.0238095238095238	1.32473347547974	0.533539330973099	0.733332782571536
GO:0005096	GTPase activator activity	5/335	271/18639	0.018450184501845	1.02654623561161	0.539088428746062	0.73938667721859
GO:0008200	ion channel inhibitor activity	1/335	43/18639	0.0232558139534884	1.29392572023603	0.54194199398993	0.741725695164184
GO:0140098	catalytic activity, acting on RNA	7/335	387/18639	0.0180878552971576	1.00638667129469	0.546439677401572	0.746300278227094
GO:0003954	NADH dehydrogenase activity	1/335	44/18639	0.0227272727272727	1.26451831750339	0.550193738021624	0.746691501600775
GO:0016248	channel inhibitor activity	1/335	44/18639	0.0227272727272727	1.26451831750339	0.550193738021624	0.746691501600775
GO:0030020	extracellular matrix structural constituent conferring tensile strength	1/335	44/18639	0.0227272727272727	1.26451831750339	0.550193738021624	0.746691501600775
GO:0004866	endopeptidase inhibitor activity	3/335	161/18639	0.0186335403726708	1.03674793733197	0.555338061607189	0.750840060622849
GO:0051539	4 iron, 4 sulfur cluster binding	1/335	45/18639	0.0222222222222222	1.23641791044776	0.558297265731371	0.750840060622849
GO:0140303	intramembrane lipid transporter activity	1/335	45/18639	0.0222222222222222	1.23641791044776	0.558297265731371	0.750840060622849
GO:0141110	transporter inhibitor activity	1/335	45/18639	0.0222222222222222	1.23641791044776	0.558297265731371	0.750840060622849
GO:0140097	catalytic activity, acting on DNA	6/335	336/18639	0.0178571428571429	0.993550106609808	0.563558066237647	0.750840060622849
GO:0004180	carboxypeptidase activity	1/335	46/18639	0.0217391304347826	1.20953926022064	0.566255231525713	0.750840060622849
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	1/335	46/18639	0.0217391304347826	1.20953926022064	0.566255231525713	0.750840060622849
GO:0008013	beta-catenin binding	2/335	106/18639	0.0188679245283019	1.04978879188961	0.570762572258282	0.750840060622849
GO:0061749	forked DNA-dependent helicase activity	1/335	47/18639	0.0212765957446809	1.1838043823436	0.574070242413621	0.750840060622849
GO:0140938	histone H3 methyltransferase activity	1/335	47/18639	0.0212765957446809	1.1838043823436	0.574070242413621	0.750840060622849
GO:1990518	single-stranded 3'-5' DNA helicase activity	1/335	47/18639	0.0212765957446809	1.1838043823436	0.574070242413621	0.750840060622849
GO:0019888	protein phosphatase regulator activity	2/335	107/18639	0.0186915887850467	1.03997768168503	0.575877057510313	0.750840060622849
GO:0009378	four-way junction helicase activity	1/335	48/18639	0.0208333333333333	1.15914179104478	0.581744858850338	0.750840060622849
GO:0036121	double-stranded DNA helicase activity	1/335	48/18639	0.0208333333333333	1.15914179104478	0.581744858850338	0.750840060622849
GO:0038187	pattern recognition receptor activity	1/335	48/18639	0.0208333333333333	1.15914179104478	0.581744858850338	0.750840060622849
GO:0043138	3'-5' DNA helicase activity	1/335	48/18639	0.0208333333333333	1.15914179104478	0.581744858850338	0.750840060622849
GO:0140693	molecular condensate scaffold activity	1/335	48/18639	0.0208333333333333	1.15914179104478	0.581744858850338	0.750840060622849
GO:0004620	phospholipase activity	2/335	109/18639	0.018348623853211	1.02089552238806	0.585972414871231	0.750840060622849
GO:0030414	peptidase inhibitor activity	3/335	169/18639	0.0177514792899408	0.987671111896141	0.588266298328939	0.750840060622849
GO:0005004	GPI-linked ephrin receptor activity	1/335	49/18639	0.0204081632653061	1.13548583612549	0.58928159556623	0.750840060622849
GO:0005008	hepatocyte growth factor receptor activity	1/335	49/18639	0.0204081632653061	1.13548583612549	0.58928159556623	0.750840060622849
GO:0005009	insulin receptor activity	1/335	49/18639	0.0204081632653061	1.13548583612549	0.58928159556623	0.750840060622849
GO:0005011	macrophage colony-stimulating factor receptor activity	1/335	49/18639	0.0204081632653061	1.13548583612549	0.58928159556623	0.750840060622849
GO:0005018	platelet-derived growth factor alpha-receptor activity	1/335	49/18639	0.0204081632653061	1.13548583612549	0.58928159556623	0.750840060622849
GO:0005020	stem cell factor receptor activity	1/335	49/18639	0.0204081632653061	1.13548583612549	0.58928159556623	0.750840060622849
GO:0008288	boss receptor activity	1/335	49/18639	0.0204081632653061	1.13548583612549	0.58928159556623	0.750840060622849
GO:0035254	glutamate receptor binding	1/335	49/18639	0.0204081632653061	1.13548583612549	0.58928159556623	0.750840060622849
GO:0036332	placental growth factor receptor activity	1/335	49/18639	0.0204081632653061	1.13548583612549	0.58928159556623	0.750840060622849
GO:0038062	protein tyrosine kinase collagen receptor activity	1/335	49/18639	0.0204081632653061	1.13548583612549	0.58928159556623	0.750840060622849
GO:0060175	brain-derived neurotrophic factor receptor activity	1/335	49/18639	0.0204081632653061	1.13548583612549	0.58928159556623	0.750840060622849
GO:0060590	ATPase regulator activity	1/335	49/18639	0.0204081632653061	1.13548583612549	0.58928159556623	0.750840060622849
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	4/335	229/18639	0.0174672489082969	0.971856872841035	0.592043964034345	0.752846030972816
GO:0005085	guanyl-nucleotide exchange factor activity	4/335	230/18639	0.0173913043478261	0.967631408176509	0.595484440562717	0.752846030972816
GO:0005007	fibroblast growth factor receptor activity	1/335	50/18639	0.02	1.11277611940299	0.596682922380932	0.752846030972816
GO:0005017	platelet-derived growth factor receptor activity	1/335	50/18639	0.02	1.11277611940299	0.596682922380932	0.752846030972816
GO:0005019	platelet-derived growth factor beta-receptor activity	1/335	50/18639	0.02	1.11277611940299	0.596682922380932	0.752846030972816
GO:0005021	vascular endothelial growth factor receptor activity	1/335	51/18639	0.0196078431372549	1.09095697980685	0.603951265003041	0.756109529441792
GO:0005030	neurotrophin receptor activity	1/335	51/18639	0.0196078431372549	1.09095697980685	0.603951265003041	0.756109529441792
GO:0005048	signal sequence binding	1/335	51/18639	0.0196078431372549	1.09095697980685	0.603951265003041	0.756109529441792
GO:0030544	Hsp70 protein binding	1/335	51/18639	0.0196078431372549	1.09095697980685	0.603951265003041	0.756109529441792
GO:0141003	histone H2AX kinase activity	6/335	354/18639	0.0169491525423729	0.943030609663547	0.614457935638103	0.758090845627433
GO:0004252	serine-type endopeptidase activity	3/335	176/18639	0.0170454545454545	0.948388738127544	0.615767979965199	0.758090845627433
GO:0005003	ephrin receptor activity	1/335	53/18639	0.0188679245283019	1.04978879188961	0.618098484647682	0.758090845627433
GO:0005005	transmembrane-ephrin receptor activity	1/335	53/18639	0.0188679245283019	1.04978879188961	0.618098484647682	0.758090845627433
GO:0016860	intramolecular oxidoreductase activity	1/335	53/18639	0.0188679245283019	1.04978879188961	0.618098484647682	0.758090845627433
GO:0038064	collagen receptor activity	1/335	53/18639	0.0188679245283019	1.04978879188961	0.618098484647682	0.758090845627433
GO:0043021	ribonucleoprotein complex binding	3/335	177/18639	0.0169491525423729	0.943030609663547	0.619594388851622	0.758090845627433
GO:0015294	solute:monoatomic cation symporter activity	2/335	116/18639	0.0172413793103448	0.959289758106022	0.61990059810958	0.758090845627433
GO:0019208	phosphatase regulator activity	2/335	117/18639	0.0170940170940171	0.951090700344432	0.624569202632051	0.758090845627433
GO:0050661	NADP binding	1/335	54/18639	0.0185185185185185	1.03034825870647	0.624981999532166	0.758090845627433
GO:0051287	NAD binding	1/335	54/18639	0.0185185185185185	1.03034825870647	0.624981999532166	0.758090845627433
GO:0022853	active monoatomic ion transmembrane transporter activity	2/335	118/18639	0.0169491525423729	0.943030609663547	0.629193395100342	0.758090845627433
GO:0098632	cell-cell adhesion mediator activity	1/335	55/18639	0.0181818181818182	1.01161465400271	0.631741807450204	0.758090845627433
GO:0170055	lipid transmembrane transporter activity	1/335	56/18639	0.0178571428571429	0.993550106609808	0.638380125062353	0.758090845627433
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	4/335	243/18639	0.0164609053497942	0.915865118850194	0.638607896243941	0.758090845627433
GO:0004676	3-phosphoinositide-dependent protein kinase activity	4/335	245/18639	0.0163265306122449	0.908388668900396	0.644971155537589	0.758090845627433
GO:0004711	ribosomal protein S6 kinase activity	4/335	245/18639	0.0163265306122449	0.908388668900396	0.644971155537589	0.758090845627433
GO:0035175	histone H3S10 kinase activity	4/335	245/18639	0.0163265306122449	0.908388668900396	0.644971155537589	0.758090845627433
GO:0035979	histone H2AXS139 kinase activity	4/335	245/18639	0.0163265306122449	0.908388668900396	0.644971155537589	0.758090845627433
GO:0044022	histone H3S28 kinase activity	4/335	245/18639	0.0163265306122449	0.908388668900396	0.644971155537589	0.758090845627433
GO:0044023	histone H4S1 kinase activity	4/335	245/18639	0.0163265306122449	0.908388668900396	0.644971155537589	0.758090845627433
GO:0044024	histone H2AS1 kinase activity	4/335	245/18639	0.0163265306122449	0.908388668900396	0.644971155537589	0.758090845627433
GO:0044025	histone H2BS14 kinase activity	4/335	245/18639	0.0163265306122449	0.908388668900396	0.644971155537589	0.758090845627433
GO:0072354	histone H3T3 kinase activity	4/335	245/18639	0.0163265306122449	0.908388668900396	0.644971155537589	0.758090845627433
GO:0072371	histone H2AS121 kinase activity	4/335	245/18639	0.0163265306122449	0.908388668900396	0.644971155537589	0.758090845627433
GO:0072518	Rho-dependent protein serine/threonine kinase activity	4/335	245/18639	0.0163265306122449	0.908388668900396	0.644971155537589	0.758090845627433
GO:0140823	histone H2BS36 kinase activity	4/335	245/18639	0.0163265306122449	0.908388668900396	0.644971155537589	0.758090845627433
GO:0140855	histone H3S57 kinase activity	4/335	245/18639	0.0163265306122449	0.908388668900396	0.644971155537589	0.758090845627433
GO:0140995	histone H2A kinase activity	4/335	245/18639	0.0163265306122449	0.908388668900396	0.644971155537589	0.758090845627433
GO:0140997	histone H4 kinase activity	4/335	245/18639	0.0163265306122449	0.908388668900396	0.644971155537589	0.758090845627433
GO:0140998	histone H2B kinase activity	4/335	245/18639	0.0163265306122449	0.908388668900396	0.644971155537589	0.758090845627433
GO:1990244	histone H2AT120 kinase activity	4/335	245/18639	0.0163265306122449	0.908388668900396	0.644971155537589	0.758090845627433
GO:0004677	DNA-dependent protein kinase activity	4/335	246/18639	0.016260162601626	0.904696032034947	0.648125111922338	0.758090845627433
GO:0140857	histone H3T45 kinase activity	4/335	246/18639	0.016260162601626	0.904696032034947	0.648125111922338	0.758090845627433
GO:0033218	amide binding	4/335	247/18639	0.0161943319838057	0.901033295063146	0.651260546791983	0.758090845627433
GO:0035403	histone H3T6 kinase activity	4/335	247/18639	0.0161943319838057	0.901033295063146	0.651260546791983	0.758090845627433
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	1/335	58/18639	0.0172413793103448	0.959289758106022	0.651300958704683	0.758090845627433
GO:0017116	single-stranded DNA helicase activity	1/335	58/18639	0.0172413793103448	0.959289758106022	0.651300958704683	0.758090845627433
GO:0061980	regulatory RNA binding	1/335	58/18639	0.0172413793103448	0.959289758106022	0.651300958704683	0.758090845627433
GO:0004679	AMP-activated protein kinase activity	4/335	248/18639	0.0161290322580645	0.89740009629273	0.654377410019139	0.760301810921518
GO:0004879	nuclear receptor activity	1/335	59/18639	0.0169491525423729	0.943030609663547	0.657587712853218	0.761293301977023
GO:0036002	pre-mRNA binding	1/335	59/18639	0.0169491525423729	0.943030609663547	0.657587712853218	0.761293301977023
GO:0001098	basal transcription machinery binding	1/335	60/18639	0.0166666666666667	0.927313432835821	0.66376145430608	0.762971351390974
GO:0001099	basal RNA polymerase II transcription machinery binding	1/335	60/18639	0.0166666666666667	0.927313432835821	0.66376145430608	0.762971351390974
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	1/335	60/18639	0.0166666666666667	0.927313432835821	0.66376145430608	0.762971351390974
GO:0098531	ligand-modulated transcription factor activity	1/335	60/18639	0.0166666666666667	0.927313432835821	0.66376145430608	0.762971351390974
GO:0016836	hydro-lyase activity	1/335	61/18639	0.0163934426229508	0.912111573281135	0.669824208642022	0.768572715422284
GO:0015179	L-amino acid transmembrane transporter activity	1/335	62/18639	0.0161290322580645	0.89740009629273	0.67577796524149	0.774029371535465
GO:0016298	lipase activity	2/335	130/18639	0.0153846153846154	0.855981630309989	0.681260418747993	0.777967388593306
GO:1901682	sulfur compound transmembrane transporter activity	1/335	63/18639	0.0158730158730159	0.883155650319829	0.681624677931596	0.777967388593306
GO:0004536	DNA nuclease activity	1/335	64/18639	0.015625	0.869356343283582	0.68736626561963	0.783136874056933
GO:0016758	hexosyltransferase activity	3/335	197/18639	0.0152284263959391	0.847291461474354	0.690632593310392	0.78547298464527
GO:0120013	lipid transfer activity	1/335	65/18639	0.0153846153846154	0.855981630309989	0.693004612915319	0.786785553503157
GO:0008235	metalloexopeptidase activity	1/335	66/18639	0.0151515151515152	0.843012211668928	0.698541570742032	0.79168044684097
GO:0016500	protein-hormone receptor activity	1/335	67/18639	0.0149253731343284	0.830429939852974	0.703978956937123	0.795053157659758
GO:0042054	histone methyltransferase activity	1/335	67/18639	0.0149253731343284	0.830429939852974	0.703978956937123	0.795053157659758
GO:0003777	microtubule motor activity	1/335	68/18639	0.0147058823529412	0.818217734855136	0.709318556841606	0.798292313100483
GO:0005548	phospholipid transporter activity	1/335	68/18639	0.0147058823529412	0.818217734855136	0.709318556841606	0.798292313100483
GO:0016279	protein-lysine N-methyltransferase activity	1/335	69/18639	0.0144927536231884	0.806359506813757	0.714562123879356	0.801609571657594
GO:0070851	growth factor receptor binding	2/335	139/18639	0.0143884892086331	0.800558359282723	0.716276790104438	0.801609571657594
GO:0140767	enzyme-substrate adaptor activity	2/335	139/18639	0.0143884892086331	0.800558359282723	0.716276790104438	0.801609571657594
GO:0008028	monocarboxylic acid transmembrane transporter activity	1/335	70/18639	0.0142857142857143	0.794840085287846	0.719711380126013	0.801609571657594
GO:0016278	lysine N-methyltransferase activity	1/335	70/18639	0.0142857142857143	0.794840085287846	0.719711380126013	0.801609571657594
GO:0097110	scaffold protein binding	1/335	70/18639	0.0142857142857143	0.794840085287846	0.719711380126013	0.801609571657594
GO:0004518	nuclease activity	3/335	209/18639	0.0143540669856459	0.798643147896879	0.728231810145574	0.809703527287506
GO:0003678	DNA helicase activity	1/335	74/18639	0.0135135135135135	0.751875756353368	0.739398672542116	0.817896476818848
GO:0003684	damaged DNA binding	1/335	74/18639	0.0135135135135135	0.751875756353368	0.739398672542116	0.817896476818848
GO:0048029	monosaccharide binding	1/335	74/18639	0.0135135135135135	0.751875756353368	0.739398672542116	0.817896476818848
GO:0015293	symporter activity	2/335	146/18639	0.0136986301369863	0.76217542424862	0.741233302396565	0.818524296321677
GO:0017022	myosin binding	1/335	76/18639	0.0131578947368421	0.732089552238806	0.74871901610295	0.822572252385214
GO:0051536	iron-sulfur cluster binding	1/335	76/18639	0.0131578947368421	0.732089552238806	0.74871901610295	0.822572252385214
GO:0098631	cell adhesion mediator activity	1/335	76/18639	0.0131578947368421	0.732089552238806	0.74871901610295	0.822572252385214
GO:0051540	metal cluster binding	1/335	77/18639	0.012987012987013	0.722581895716224	0.753253796558993	0.82614932525825
GO:0015370	solute:sodium symporter activity	1/335	79/18639	0.0126582278481013	0.704288683166446	0.762080028276165	0.834413047909157
GO:0005506	iron ion binding	2/335	154/18639	0.012987012987013	0.722581895716224	0.767437816381207	0.838857579327004
GO:0015101	organic cation transmembrane transporter activity	1/335	81/18639	0.0123456790123457	0.686898839137645	0.770591450145222	0.840881886476036
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	1/335	83/18639	0.0120481927710843	0.670347059881316	0.778799258234636	0.846976971076725
GO:0030165	PDZ domain binding	1/335	83/18639	0.0120481927710843	0.670347059881316	0.778799258234636	0.846976971076725
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	1/335	86/18639	0.0116279069767442	0.646962860118015	0.790565212331132	0.858327944816658
GO:0046982	protein heterodimerization activity	5/335	369/18639	0.013550135501355	0.753913360029123	0.796033510196915	0.862814844944979
GO:0016651	oxidoreductase activity, acting on NAD(P)H	1/335	88/18639	0.0113636363636364	0.632259158751696	0.798060397688265	0.863562842389646
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	2/335	167/18639	0.0119760479041916	0.66633300563053	0.805109767062639	0.869733962412149
GO:0042562	hormone binding	1/335	94/18639	0.0106382978723404	0.591902191171801	0.818978903823179	0.88323935203635
GO:0008276	protein methyltransferase activity	1/335	95/18639	0.0105263157894737	0.585671641791045	0.822248899359401	0.885287981643622
GO:0022804	active transmembrane transporter activity	6/335	457/18639	0.0131291028446389	0.730487605735001	0.833358938367578	0.895756862205417
GO:0015171	amino acid transmembrane transporter activity	1/335	102/18639	0.00980392156862745	0.545478489903424	0.843547686575626	0.905202334763878
GO:0008237	metallopeptidase activity	2/335	184/18639	0.0108695652173913	0.604769630110318	0.8461539645946	0.90522898397031
GO:0004722	protein serine/threonine phosphatase activity	1/335	103/18639	0.00970873786407767	0.540182582234459	0.84637508717967	0.90522898397031
GO:0015078	proton transmembrane transporter activity	2/335	185/18639	0.0108108108108108	0.601500605082695	0.848305709414148	0.905794195506677
GO:0031406	carboxylic acid binding	2/335	187/18639	0.0106951871657754	0.595067443531008	0.852527449058385	0.907198001937261
GO:0004497	monooxygenase activity	1/335	106/18639	0.00943396226415094	0.524894395944804	0.854555252425636	0.907198001937261
GO:0046943	carboxylic acid transmembrane transporter activity	2/335	188/18639	0.0106382978723404	0.591902191171801	0.854598010795997	0.907198001937261
GO:0005342	organic acid transmembrane transporter activity	2/335	189/18639	0.0105820105820106	0.588770433546553	0.856642076132707	0.907198001937261
GO:0043177	organic acid binding	2/335	189/18639	0.0105820105820106	0.588770433546553	0.856642076132707	0.907198001937261
GO:0004222	metalloendopeptidase activity	1/335	110/18639	0.00909090909090909	0.505807327001357	0.864790504149483	0.913049449136582
GO:0008514	organic anion transmembrane transporter activity	3/335	269/18639	0.0111524163568773	0.620507129778616	0.864994214971499	0.913049449136582
GO:1902936	phosphatidylinositol bisphosphate binding	1/335	111/18639	0.00900900900900901	0.501250504235579	0.867235060310631	0.913921450180535
GO:0008168	methyltransferase activity	2/335	204/18639	0.00980392156862745	0.545478489903424	0.884310152758838	0.930397978309787
GO:0008528	G protein-coupled peptide receptor activity	1/335	122/18639	0.00819672131147541	0.456055786640568	0.891384149606569	0.933280649344965
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	1/335	122/18639	0.00819672131147541	0.456055786640568	0.891384149606569	0.933280649344965
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	1/335	122/18639	0.00819672131147541	0.456055786640568	0.891384149606569	0.933280649344965
GO:0016741	transferase activity, transferring one-carbon groups	2/335	215/18639	0.00930232558139535	0.517570288094412	0.901371523289776	0.940572019921318
GO:0001653	peptide receptor activity	1/335	128/18639	0.0078125	0.434678171641791	0.902655171421249	0.940572019921318
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	1/335	130/18639	0.00769230769230769	0.427990815154994	0.906146749465286	0.940572019921318
GO:0005262	calcium channel activity	1/335	131/18639	0.00763358778625954	0.424723709695796	0.907845427888168	0.940572019921318
GO:0031072	heat shock protein binding	1/335	131/18639	0.00763358778625954	0.424723709695796	0.907845427888168	0.940572019921318
GO:0005179	hormone activity	1/335	132/18639	0.00757575757575758	0.421506105834464	0.909513451535103	0.940572019921318
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	1/335	132/18639	0.00757575757575758	0.421506105834464	0.909513451535103	0.940572019921318
GO:0046873	metal ion transmembrane transporter activity	5/335	450/18639	0.0111111111111111	0.618208955223881	0.90999614930468	0.940572019921318
GO:0099094	ligand-gated monoatomic cation channel activity	1/335	136/18639	0.00735294117647059	0.409108867427568	0.915889882536946	0.945151540125986
GO:0140101	catalytic activity, acting on a tRNA	1/335	139/18639	0.00719424460431655	0.400279179641362	0.920376391049686	0.948266584717858
GO:0008194	UDP-glycosyltransferase activity	1/335	145/18639	0.00689655172413793	0.383715903242409	0.928646150897167	0.955263397260461
GO:0015085	calcium ion transmembrane transporter activity	1/335	147/18639	0.00680272108843537	0.378495278708498	0.931207811963048	0.956375590664752
GO:0008509	monoatomic anion transmembrane transporter activity	1/335	149/18639	0.00671140939597315	0.373414805168787	0.933677771993719	0.957103148920408
GO:0019842	vitamin binding	1/335	150/18639	0.00666666666666667	0.370925373134328	0.934879391592535	0.957103148920408
GO:0005543	phospholipid binding	5/335	497/18639	0.0100603621730382	0.559746538935103	0.946542373916213	0.967510084730813
GO:0015081	sodium ion transmembrane transporter activity	1/335	164/18639	0.00609756097560976	0.339261012013105	0.949591507831104	0.968780606831994
GO:0003730	mRNA 3'-UTR binding	2/335	262/18639	0.00763358778625954	0.424723709695796	0.951040027745718	0.968780606831994
GO:0016874	ligase activity	1/335	167/18639	0.00598802395209581	0.333166502815265	0.952284342628972	0.968780606831994
GO:0016853	isomerase activity	1/335	180/18639	0.00555555555555556	0.30910447761194	0.962390552464943	0.97354546605966
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	1/335	181/18639	0.00552486187845304	0.307396718067123	0.963073101082108	0.97354546605966
GO:0035091	phosphatidylinositol binding	2/335	284/18639	0.00704225352112676	0.391822577254572	0.965033777206064	0.97354546605966
GO:1901981	phosphatidylinositol phosphate binding	1/335	185/18639	0.00540540540540541	0.300750302541347	0.965681995812278	0.97354546605966
GO:0015276	ligand-gated monoatomic ion channel activity	1/335	186/18639	0.00537634408602151	0.29913336543091	0.966304978981395	0.97354546605966
GO:0015291	secondary active transmembrane transporter activity	2/335	287/18639	0.00696864111498258	0.38772687087212	0.966615145000557	0.97354546605966
GO:0022834	ligand-gated channel activity	1/335	188/18639	0.00531914893617021	0.2959510955859	0.967517320758981	0.97354546605966
GO:0022836	gated channel activity	1/335	318/18639	0.00314465408805031	0.174964798648268	0.997024929321217	0.999732156352903
GO:0005261	monoatomic cation channel activity	1/335	341/18639	0.00293255131964809	0.163163653871405	0.998054415837326	0.999732156352903
GO:0045182	translation regulator activity	1/335	356/18639	0.00280898876404494	0.156288780815026	0.998525542630807	0.999732156352903
GO:0005216	monoatomic ion channel activity	1/335	448/18639	0.00223214285714286	0.124193763326226	0.999732156352903	0.999732156352903