ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0005201	extracellular matrix structural constituent	59/2342	168/18639	0.351190476190476	2.79497834573624	3.74272789359857e-14	4.86180353378454e-11
GO:0003779	actin binding	109/2342	443/18639	0.246049661399549	1.95820650675755	1.80610819822271e-12	1.17306727474565e-09
GO:0005178	integrin binding	50/2342	161/18639	0.31055900621118	2.47160944353979	5.04693630136476e-10	2.07728254005845e-07
GO:0005516	calmodulin binding	59/2342	207/18639	0.285024154589372	2.26838822262652	6.39655901480663e-10	2.07728254005845e-07
GO:0019838	growth factor binding	44/2342	136/18639	0.323529411764706	2.57483548500527	1.30262635082576e-09	3.38422325944532e-07
GO:0019199	transmembrane receptor protein kinase activity	30/2342	78/18639	0.384615384615385	3.06099323392235	5.99225963929931e-09	1.2973242119083e-06
GO:0005017	platelet-derived growth factor receptor activity	22/2342	50/18639	0.44	3.50177625960717	3.58015893606826e-08	5.81328307244084e-06
GO:0005019	platelet-derived growth factor beta-receptor activity	22/2342	50/18639	0.44	3.50177625960717	3.58015893606826e-08	5.81328307244084e-06
GO:0008201	heparin binding	48/2342	172/18639	0.27906976744186	2.22099974182273	5.07244683484441e-08	6.55502668485179e-06
GO:0005010	insulin-like growth factor receptor activity	22/2342	51/18639	0.431372549019608	3.43311398000703	5.55083091095995e-08	6.55502668485179e-06
GO:0005030	neurotrophin receptor activity	22/2342	51/18639	0.431372549019608	3.43311398000703	5.55083091095995e-08	6.55502668485179e-06
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	102/2342	484/18639	0.210743801652893	1.6772219124715	7.30697554420596e-08	6.77646284004697e-06
GO:0017124	SH3 domain binding	36/2342	115/18639	0.31304347826087	2.49138231908811	1.03394724196356e-07	6.77646284004697e-06
GO:0030695	GTPase regulator activity	102/2342	489/18639	0.208588957055215	1.66007240416403	1.24219743905248e-07	6.77646284004697e-06
GO:0005004	GPI-linked ephrin receptor activity	21/2342	49/18639	0.428571428571429	3.41082103208491	1.27344184698606e-07	6.77646284004697e-06
GO:0005008	hepatocyte growth factor receptor activity	21/2342	49/18639	0.428571428571429	3.41082103208491	1.27344184698606e-07	6.77646284004697e-06
GO:0005009	insulin receptor activity	21/2342	49/18639	0.428571428571429	3.41082103208491	1.27344184698606e-07	6.77646284004697e-06
GO:0005011	macrophage colony-stimulating factor receptor activity	21/2342	49/18639	0.428571428571429	3.41082103208491	1.27344184698606e-07	6.77646284004697e-06
GO:0005018	platelet-derived growth factor alpha-receptor activity	21/2342	49/18639	0.428571428571429	3.41082103208491	1.27344184698606e-07	6.77646284004697e-06
GO:0005020	stem cell factor receptor activity	21/2342	49/18639	0.428571428571429	3.41082103208491	1.27344184698606e-07	6.77646284004697e-06
GO:0008288	boss receptor activity	21/2342	49/18639	0.428571428571429	3.41082103208491	1.27344184698606e-07	6.77646284004697e-06
GO:0036332	placental growth factor receptor activity	21/2342	49/18639	0.428571428571429	3.41082103208491	1.27344184698606e-07	6.77646284004697e-06
GO:0038062	protein tyrosine kinase collagen receptor activity	21/2342	49/18639	0.428571428571429	3.41082103208491	1.27344184698606e-07	6.77646284004697e-06
GO:0060175	brain-derived neurotrophic factor receptor activity	21/2342	49/18639	0.428571428571429	3.41082103208491	1.27344184698606e-07	6.77646284004697e-06
GO:0005539	glycosaminoglycan binding	60/2342	242/18639	0.247933884297521	1.97320224996648	1.30416913780735e-07	6.77646284004697e-06
GO:0060589	nucleoside-triphosphatase regulator activity	102/2342	490/18639	0.208163265306122	1.65668450129838	1.3790373851633e-07	6.88988293587359e-06
GO:0001216	DNA-binding transcription activator activity	102/2342	491/18639	0.207739307535642	1.65331039844442	1.53013219777089e-07	7.36163601816442e-06
GO:0005006	epidermal growth factor receptor activity	21/2342	50/18639	0.42	3.34260461144321	1.93633650288137e-07	8.67345212842378e-06
GO:0005007	fibroblast growth factor receptor activity	21/2342	50/18639	0.42	3.34260461144321	1.93633650288137e-07	8.67345212842378e-06
GO:0005021	vascular endothelial growth factor receptor activity	21/2342	51/18639	0.411764705882353	3.27706334455217	2.90321389113112e-07	1.25709161485977e-05
GO:0004714	transmembrane receptor protein tyrosine kinase activity	23/2342	60/18639	0.383333333333333	3.05078992314261	3.75152496450977e-07	1.57200997706393e-05
GO:0140297	DNA-binding transcription factor binding	100/2342	488/18639	0.204918032786885	1.63085705086027	3.97477730253176e-07	1.61351116124649e-05
GO:0042578	phosphoric ester hydrolase activity	79/2342	363/18639	0.21763085399449	1.73203308608168	5.62888268487557e-07	2.21573291141011e-05
GO:0005003	ephrin receptor activity	21/2342	53/18639	0.39622641509434	3.15340057683322	6.27487289641287e-07	2.26418330345565e-05
GO:0005005	transmembrane-ephrin receptor activity	21/2342	53/18639	0.39622641509434	3.15340057683322	6.27487289641287e-07	2.26418330345565e-05
GO:0038064	collagen receptor activity	21/2342	53/18639	0.39622641509434	3.15340057683322	6.27487289641287e-07	2.26418330345565e-05
GO:0141003	histone H2AX kinase activity	77/2342	354/18639	0.217514124293785	1.73110408313914	7.96955109634589e-07	2.79795861463603e-05
GO:0035401	histone H3Y41 kinase activity	34/2342	115/18639	0.295652173913043	2.35297219024988	1.02919206169505e-06	3.42800125164581e-05
GO:0140801	histone H2AXY142 kinase activity	34/2342	115/18639	0.295652173913043	2.35297219024988	1.02919206169505e-06	3.42800125164581e-05
GO:0140996	histone H3 kinase activity	77/2342	357/18639	0.215686274509804	1.71655699000352	1.12524316891477e-06	3.65422719105072e-05
GO:0035173	histone kinase activity	77/2342	360/18639	0.213888888888889	1.70225234842015	1.57787626846765e-06	4.99917383594994e-05
GO:0004713	protein tyrosine kinase activity	38/2342	140/18639	0.271428571428571	2.16018665365378	2.53303198959543e-06	7.83430608210586e-05
GO:0043548	phosphatidylinositol 3-kinase binding	13/2342	26/18639	0.5	3.97929120409906	3.97794100100406e-06	0.000120170822332658
GO:0045296	cadherin binding	71/2342	334/18639	0.212574850299401	1.69179446401816	4.98100693456928e-06	0.000147052909272852
GO:0001221	transcription coregulator binding	32/2342	115/18639	0.278260869565217	2.21456206141165	8.71686938308521e-06	0.000251626962858393
GO:0004674	protein serine/threonine kinase activity	86/2342	433/18639	0.198614318706697	1.58068842287538	9.16542874386169e-06	0.000258823737788616
GO:0005543	phospholipid binding	96/2342	497/18639	0.193158953722334	1.53727145108052	9.50660209825593e-06	0.000262746300545414
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	72/2342	349/18639	0.206303724928367	1.64188519596064	1.27643228968259e-05	0.000335824867237857
GO:0016500	protein-hormone receptor activity	22/2342	67/18639	0.328358208955224	2.61326586537849	1.29262843432585e-05	0.000335824867237857
GO:0050840	extracellular matrix binding	22/2342	67/18639	0.328358208955224	2.61326586537849	1.29262843432585e-05	0.000335824867237857
GO:0005518	collagen binding	23/2342	72/18639	0.319444444444444	2.54232493595218	1.38199438295045e-05	0.000352002098716203
GO:0005096	GTPase activator activity	59/2342	271/18639	0.217712177121771	1.73268030289184	1.44261654998831e-05	0.000360376711237463
GO:0005319	lipid transporter activity	43/2342	178/18639	0.241573033707865	1.92257889636247	1.49796612192867e-05	0.000367143017431196
GO:0032934	sterol binding	22/2342	68/18639	0.323529411764706	2.57483548500527	1.68593359630618e-05	0.000405560692889208
GO:0030165	PDZ domain binding	25/2342	83/18639	0.301204819277108	2.39716337596329	1.87220743186209e-05	0.0004421813552707
GO:1901681	sulfur compound binding	59/2342	275/18639	0.214545454545455	1.70747768030432	2.28318255664581e-05	0.000523595671312292
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	26/2342	89/18639	0.292134831460674	2.32497913048484	2.3378405647508e-05	0.000523595671312292
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	26/2342	89/18639	0.292134831460674	2.32497913048484	2.3378405647508e-05	0.000523595671312292
GO:0140793	histone H2AXY142 phosphatase activity	26/2342	90/18639	0.288888888888889	2.29914602903501	2.89880109749755e-05	0.000638227563669376
GO:0140327	flippase activity	9/2342	16/18639	0.5625	4.47670260461144	3.8283569651156e-05	0.000828839282947528
GO:0043121	neurotrophin binding	7/2342	10/18639	0.7	5.57100768573868	4.15818184596933e-05	0.000885488232444944
GO:0031994	insulin-like growth factor I binding	8/2342	13/18639	0.615384615384615	4.89758917427577	4.39370474256787e-05	0.000905940073110423
GO:0140333	glycerophospholipid flippase activity	8/2342	13/18639	0.615384615384615	4.89758917427577	4.39370474256787e-05	0.000905940073110423
GO:0004725	protein tyrosine phosphatase activity	27/2342	98/18639	0.275510204081633	2.19267066348316	5.16469254071084e-05	0.0010482711891224
GO:0016791	phosphatase activity	57/2342	273/18639	0.208791208791209	1.66168204127214	6.93425891579558e-05	0.00138578497409515
GO:0046332	SMAD binding	23/2342	79/18639	0.291139240506329	2.31705563782983	7.18696269011406e-05	0.00141452492946336
GO:0106310	protein serine kinase activity	71/2342	361/18639	0.196675900277008	1.56526136006113	7.38035207173598e-05	0.00143090706584851
GO:0043178	alcohol binding	25/2342	92/18639	0.271739130434783	2.16265826309732	0.000122881299537109	0.00234739423674565
GO:0140789	histone phosphatase activity	33/2342	136/18639	0.242647058823529	1.93112661375396	0.000128170537410516	0.00240894183750724
GO:0005085	guanyl-nucleotide exchange factor activity	49/2342	230/18639	0.21304347826087	1.6955240782683	0.000129812108256741	0.00240894183750724
GO:0030021	extracellular matrix structural constituent conferring compression resistance	10/2342	22/18639	0.454545454545455	3.61753745827187	0.000147699692172609	0.00270228028355238
GO:0001222	transcription corepressor binding	16/2342	49/18639	0.326530612244898	2.59872078635041	0.000206284386409803	0.00372171413814353
GO:0005520	insulin-like growth factor binding	9/2342	19/18639	0.473684210526316	3.76985482493595	0.000216825509534761	0.00382159128362929
GO:0015485	cholesterol binding	17/2342	54/18639	0.314814814814815	2.50547964702533	0.00021770419937534	0.00382159128362929
GO:0005158	insulin receptor binding	10/2342	23/18639	0.434782608695652	3.46025322095571	0.000231981538140708	0.00401792024059706
GO:0035591	signaling adaptor activity	31/2342	129/18639	0.24031007751938	1.91252755545846	0.000243244261903819	0.00415755652911923
GO:0098632	cell-cell adhesion mediator activity	17/2342	55/18639	0.309090909090909	2.45992547162487	0.000278603217660858	0.00470007246417473
GO:0070411	I-SMAD binding	8/2342	16/18639	0.5	3.97929120409906	0.000309443802156041	0.00508819618988224
GO:0140328	floppase activity	8/2342	16/18639	0.5	3.97929120409906	0.000309443802156041	0.00508819618988224
GO:0051393	alpha-actinin binding	11/2342	28/18639	0.392857142857143	3.12658594607783	0.000332245542821517	0.00539483700156439
GO:0031267	small GTPase binding	56/2342	283/18639	0.197879858657244	1.57484316204627	0.000344989619329968	0.00553261130258801
GO:0051020	GTPase binding	61/2342	315/18639	0.193650793650794	1.54118579968281	0.000352270211029833	0.00558047566009454
GO:0042805	actinin binding	13/2342	37/18639	0.351351351351351	2.7962586839615	0.000357206612284363	0.00559049866695648
GO:0051015	actin filament binding	44/2342	209/18639	0.210526315789474	1.67549103330487	0.000365685845376973	0.00565507039457962
GO:0001217	DNA-binding transcription repressor activity	55/2342	278/18639	0.197841726618705	1.57453968507517	0.000389537183777	0.00595304472619204
GO:0071889	14-3-3 protein binding	12/2342	33/18639	0.363636363636364	2.8940299666175	0.0004168254055396	0.00628446196726531
GO:0043560	insulin receptor substrate binding	7/2342	13/18639	0.538461538461538	4.2853905274913	0.000420899300348023	0.00628446196726531
GO:0004857	enzyme inhibitor activity	76/2342	416/18639	0.182692307692308	1.45397178611312	0.000466086860254705	0.0068800776303507
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	53/2342	268/18639	0.197761194029851	1.57389875983023	0.000496740179070986	0.00725017407430574
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	8/2342	17/18639	0.470588235294118	3.74521525091676	0.000520266931370073	0.00742666751483214
GO:0019198	transmembrane receptor protein phosphatase activity	8/2342	17/18639	0.470588235294118	3.74521525091676	0.000520266931370073	0.00742666751483214
GO:0008013	beta-catenin binding	26/2342	106/18639	0.245283018867925	1.95210511899199	0.000532517822098379	0.00751892011854125
GO:0031625	ubiquitin protein ligase binding	58/2342	302/18639	0.19205298013245	1.52846946912414	0.000601289166015829	0.00839865189951142
GO:0001965	G-protein alpha-subunit binding	11/2342	30/18639	0.366666666666667	2.91814688300598	0.00066541019765571	0.0090114914401719
GO:0001968	fibronectin binding	11/2342	30/18639	0.366666666666667	2.91814688300598	0.00066541019765571	0.0090114914401719
GO:0008237	metallopeptidase activity	39/2342	184/18639	0.21195652173913	1.68687344521591	0.000665976272714782	0.0090114914401719
GO:0005496	steroid binding	26/2342	108/18639	0.240740740740741	1.91595502419584	0.000721486590391798	0.00966196990638088
GO:0005161	platelet-derived growth factor receptor binding	7/2342	14/18639	0.5	3.97929120409906	0.0007506046617975	0.00988177312578684
GO:0070412	R-SMAD binding	10/2342	26/18639	0.384615384615385	3.06099323392235	0.000754291006141941	0.00988177312578684
GO:0004866	endopeptidase inhibitor activity	35/2342	161/18639	0.217391304347826	1.73012661047785	0.0007607215647257	0.00988177312578684
GO:0019955	cytokine binding	32/2342	144/18639	0.222222222222222	1.76857386848847	0.000847137979234863	0.0108953686636246
GO:0140303	intramembrane lipid transporter activity	14/2342	45/18639	0.311111111111111	2.47600341588386	0.000876525721070512	0.0111628128595156
GO:0004721	phosphoprotein phosphatase activity	37/2342	175/18639	0.211428571428571	1.68267170916189	0.000946085300123807	0.0119316971345711
GO:0004222	metalloendopeptidase activity	26/2342	110/18639	0.236363636363636	1.88111947830137	0.000966422085908041	0.0120709835537937
GO:0004016	adenylate cyclase activity	6/2342	11/18639	0.545454545454545	4.34104494992625	0.00102718811878716	0.0123547904287455
GO:0010854	adenylate cyclase regulator activity	6/2342	11/18639	0.545454545454545	4.34104494992625	0.00102718811878716	0.0123547904287455
GO:0048185	activin binding	6/2342	11/18639	0.545454545454545	4.34104494992625	0.00102718811878716	0.0123547904287455
GO:0097493	structural molecule activity conferring elasticity	6/2342	11/18639	0.545454545454545	4.34104494992625	0.00102718811878716	0.0123547904287455
GO:0003712	transcription coregulator activity	86/2342	495/18639	0.173737373737374	1.38270320627281	0.00105518855844522	0.01245437482527
GO:0023026	MHC class II protein complex binding	10/2342	27/18639	0.37037037037037	2.94762311414745	0.00106423064326787	0.01245437482527
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	10/2342	27/18639	0.37037037037037	2.94762311414745	0.00106423064326787	0.01245437482527
GO:0019902	phosphatase binding	39/2342	190/18639	0.205263157894737	1.63360375747225	0.00126338167084305	0.0146529713430814
GO:0061135	endopeptidase regulator activity	38/2342	184/18639	0.206521739130435	1.64362027995396	0.00128725683603125	0.0147977577876513
GO:0043394	proteoglycan binding	12/2342	37/18639	0.324324324324324	2.58116186211831	0.00134603883986839	0.015337758359553
GO:0004896	cytokine receptor activity	23/2342	96/18639	0.239583333333333	1.90674370196413	0.00152322461815224	0.0172058154693892
GO:0050431	transforming growth factor beta binding	9/2342	24/18639	0.375	2.9844684030743	0.00170563362203445	0.0191001558191616
GO:0019903	protein phosphatase binding	31/2342	144/18639	0.215277777777778	1.71330593509821	0.00173870006928805	0.0193040289744032
GO:0035014	phosphatidylinositol 3-kinase regulator activity	6/2342	12/18639	0.5	3.97929120409906	0.00183645661187679	0.020046698645613
GO:0035259	nuclear glucocorticoid receptor binding	6/2342	12/18639	0.5	3.97929120409906	0.00183645661187679	0.020046698645613
GO:0030414	peptidase inhibitor activity	35/2342	169/18639	0.207100591715976	1.64822712595819	0.00185790328326934	0.0201118030413906
GO:0052745	inositol phosphate phosphatase activity	8/2342	20/18639	0.4	3.18343296327925	0.00190376172163615	0.0204379047636806
GO:0061134	peptidase regulator activity	44/2342	226/18639	0.194690265486726	1.54945852195008	0.00195768004323241	0.0205683577016527
GO:0004879	nuclear receptor activity	16/2342	59/18639	0.271186440677966	2.15825963612152	0.00198973067385215	0.0205683577016527
GO:0005024	transforming growth factor beta receptor activity	7/2342	16/18639	0.4375	3.48187980358668	0.00199088240402026	0.0205683577016527
GO:0005159	insulin-like growth factor receptor binding	7/2342	16/18639	0.4375	3.48187980358668	0.00199088240402026	0.0205683577016527
GO:0004629	phospholipase C activity	10/2342	29/18639	0.344827586206897	2.74433876144763	0.00199508319507948	0.0205683577016527
GO:0001223	transcription coactivator binding	13/2342	44/18639	0.295454545454545	2.35139934787672	0.00223710618339239	0.0226038734229939
GO:0030020	extracellular matrix structural constituent conferring tensile strength	13/2342	44/18639	0.295454545454545	2.35139934787672	0.00223710618339239	0.0226038734229939
GO:0098631	cell adhesion mediator activity	19/2342	76/18639	0.25	1.98964560204953	0.00224472646002018	0.0226038734229939
GO:0098531	ligand-modulated transcription factor activity	16/2342	60/18639	0.266666666666667	2.12228864218617	0.00240225281881483	0.0240040493203113
GO:0019207	kinase regulator activity	53/2342	287/18639	0.184668989547038	1.46970337154878	0.00246368787255234	0.0243872183425249
GO:0004679	AMP-activated protein kinase activity	47/2342	248/18639	0.189516129032258	1.50827973058593	0.00247814689854756	0.0243872183425249
GO:0042562	hormone binding	22/2342	94/18639	0.234042553191489	1.86264694659956	0.00261257449822881	0.0255167990466107
GO:0031624	ubiquitin conjugating enzyme binding	10/2342	30/18639	0.333333333333333	2.65286080273271	0.00265991969379135	0.0257853409122012
GO:0042277	peptide binding	47/2342	249/18639	0.188755020080321	1.50222238227033	0.00269103219715997	0.0258937098082282
GO:0019209	kinase activator activity	31/2342	148/18639	0.209459459459459	1.66700036928474	0.00272610702441939	0.0260383310641234
GO:0002020	protease binding	29/2342	136/18639	0.213235294117647	1.69705066057166	0.00278606869676358	0.026416811949605
GO:0044389	ubiquitin-like protein ligase binding	58/2342	322/18639	0.180124223602484	1.43353347725308	0.0028537300095365	0.0268622846549849
GO:0004867	serine-type endopeptidase inhibitor activity	22/2342	95/18639	0.231578947368421	1.84304013663535	0.00300471707844951	0.028080053848244
GO:0070123	transforming growth factor beta receptor activity, type III	6/2342	13/18639	0.461538461538462	3.67319188070683	0.00304979145033001	0.0282977078141334
GO:0016922	nuclear receptor binding	29/2342	137/18639	0.211678832116788	1.68466342947259	0.00311916142616064	0.028736104202714
GO:0004435	phosphatidylinositol phospholipase C activity	9/2342	26/18639	0.346153846153846	2.75489391053012	0.00322703274031468	0.0295205318990759
GO:0017147	Wnt-protein binding	10/2342	31/18639	0.32258064516129	2.56728464780585	0.00349066546884133	0.0317089121959783
GO:0140857	histone H3T45 kinase activity	46/2342	246/18639	0.186991869918699	1.48819020641103	0.00357150855223047	0.0321145416859213
GO:0044390	ubiquitin-like protein conjugating enzyme binding	11/2342	36/18639	0.305555555555556	2.43178906917165	0.00358476408349391	0.0321145416859213
GO:0005548	phospholipid transporter activity	17/2342	68/18639	0.25	1.98964560204953	0.00373430328665355	0.0332250682833079
GO:0030295	protein kinase activator activity	29/2342	139/18639	0.20863309352518	1.66042366789745	0.00388759145661004	0.0343536143002479
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	7/2342	18/18639	0.388888888888889	3.09500426985483	0.00441176508076801	0.0384623009390446
GO:0008525	phosphatidylcholine transporter activity	7/2342	18/18639	0.388888888888889	3.09500426985483	0.00441176508076801	0.0384623009390446
GO:0032395	MHC class II receptor activity	5/2342	10/18639	0.5	3.97929120409906	0.00454569751061202	0.0393657404419001
GO:0003713	transcription coactivator activity	47/2342	256/18639	0.18359375	1.46114598900512	0.00467408115011768	0.0400674632345147
GO:0003714	transcription corepressor activity	39/2342	204/18639	0.191176470588235	1.52149369568493	0.00470616933877763	0.0400674632345147
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	45/2342	243/18639	0.185185185185185	1.47381155707373	0.00471926241330311	0.0400674632345147
GO:0008191	metalloendopeptidase inhibitor activity	6/2342	14/18639	0.428571428571429	3.41082103208491	0.00477418154172941	0.040270531316276
GO:0008081	phosphoric diester hydrolase activity	20/2342	87/18639	0.229885057471264	1.82955917429842	0.00495161873866755	0.0408648433822406
GO:0097110	scaffold protein binding	17/2342	70/18639	0.242857142857143	1.93279858484812	0.00513025670804401	0.0408648433822406
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	8/2342	23/18639	0.347826086956522	2.76820257676456	0.00524386635577888	0.0408648433822406
GO:0001786	phosphatidylserine binding	15/2342	59/18639	0.254237288135593	2.02336840886393	0.00528352588373899	0.0408648433822406
GO:0004676	3-phosphoinositide-dependent protein kinase activity	45/2342	245/18639	0.183673469387755	1.4617804423221	0.00550527143332726	0.0408648433822406
GO:0004711	ribosomal protein S6 kinase activity	45/2342	245/18639	0.183673469387755	1.4617804423221	0.00550527143332726	0.0408648433822406
GO:0035175	histone H3S10 kinase activity	45/2342	245/18639	0.183673469387755	1.4617804423221	0.00550527143332726	0.0408648433822406
GO:0035979	histone H2AXS139 kinase activity	45/2342	245/18639	0.183673469387755	1.4617804423221	0.00550527143332726	0.0408648433822406
GO:0044022	histone H3S28 kinase activity	45/2342	245/18639	0.183673469387755	1.4617804423221	0.00550527143332726	0.0408648433822406
GO:0044023	histone H4S1 kinase activity	45/2342	245/18639	0.183673469387755	1.4617804423221	0.00550527143332726	0.0408648433822406
GO:0044024	histone H2AS1 kinase activity	45/2342	245/18639	0.183673469387755	1.4617804423221	0.00550527143332726	0.0408648433822406
GO:0044025	histone H2BS14 kinase activity	45/2342	245/18639	0.183673469387755	1.4617804423221	0.00550527143332726	0.0408648433822406
GO:0072354	histone H3T3 kinase activity	45/2342	245/18639	0.183673469387755	1.4617804423221	0.00550527143332726	0.0408648433822406
GO:0072371	histone H2AS121 kinase activity	45/2342	245/18639	0.183673469387755	1.4617804423221	0.00550527143332726	0.0408648433822406
GO:0072518	Rho-dependent protein serine/threonine kinase activity	45/2342	245/18639	0.183673469387755	1.4617804423221	0.00550527143332726	0.0408648433822406
GO:0140823	histone H2BS36 kinase activity	45/2342	245/18639	0.183673469387755	1.4617804423221	0.00550527143332726	0.0408648433822406
GO:0140855	histone H3S57 kinase activity	45/2342	245/18639	0.183673469387755	1.4617804423221	0.00550527143332726	0.0408648433822406
GO:0140995	histone H2A kinase activity	45/2342	245/18639	0.183673469387755	1.4617804423221	0.00550527143332726	0.0408648433822406
GO:0140997	histone H4 kinase activity	45/2342	245/18639	0.183673469387755	1.4617804423221	0.00550527143332726	0.0408648433822406
GO:0140998	histone H2B kinase activity	45/2342	245/18639	0.183673469387755	1.4617804423221	0.00550527143332726	0.0408648433822406
GO:1990244	histone H2AT120 kinase activity	45/2342	245/18639	0.183673469387755	1.4617804423221	0.00550527143332726	0.0408648433822406
GO:0030296	protein tyrosine kinase activator activity	10/2342	33/18639	0.303030303030303	2.41169163884792	0.00576057092404231	0.0425169410814259
GO:0004677	DNA-dependent protein kinase activity	45/2342	246/18639	0.182926829268293	1.4558382454021	0.00593820342163251	0.0435803742638454
GO:0140375	immune receptor activity	31/2342	156/18639	0.198717948717949	1.58151317085988	0.00617830775025534	0.045087762739223
GO:0035402	histone H3T11 kinase activity	45/2342	247/18639	0.182186234817814	1.4499441634369	0.00639959408946764	0.0461837373456581
GO:0035403	histone H3T6 kinase activity	45/2342	247/18639	0.182186234817814	1.4499441634369	0.00639959408946764	0.0461837373456581
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	8/2342	24/18639	0.333333333333333	2.65286080273271	0.0070129827226511	0.0500542008611196
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	8/2342	24/18639	0.333333333333333	2.65286080273271	0.0070129827226511	0.0500542008611196
GO:0051117	ATPase binding	19/2342	84/18639	0.226190476190476	1.80015554471148	0.00727751139155018	0.0516584005334627
GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	5/2342	11/18639	0.454545454545455	3.61753745827187	0.00747778867046606	0.0525062026104617
GO:0050998	nitric-oxide synthase binding	5/2342	11/18639	0.454545454545455	3.61753745827187	0.00747778867046606	0.0525062026104617
GO:0000287	magnesium ion binding	42/2342	230/18639	0.182608695652174	1.4533063528014	0.00789325753924979	0.0551254921692768
GO:0042974	nuclear retinoic acid receptor binding	8/2342	25/18639	0.32	2.5467463706234	0.00919740580225838	0.0638900007333349
GO:1990782	protein tyrosine kinase binding	24/2342	117/18639	0.205128205128205	1.63252972475859	0.0100186200452385	0.0692244012700253
GO:0008142	oxysterol binding	6/2342	16/18639	0.375	2.9844684030743	0.0101976847854479	0.070088849398396
GO:0019887	protein kinase regulator activity	45/2342	255/18639	0.176470588235294	1.40445571909379	0.0112959345405465	0.0751155664760126
GO:0009975	cyclase activity	7/2342	21/18639	0.333333333333333	2.65286080273271	0.0114860039980747	0.0751155664760126
GO:0005025	transforming growth factor beta receptor activity, type I	5/2342	12/18639	0.416666666666667	3.31607600341588	0.0115073115694584	0.0751155664760126
GO:0005026	transforming growth factor beta receptor activity, type II	5/2342	12/18639	0.416666666666667	3.31607600341588	0.0115073115694584	0.0751155664760126
GO:0005078	MAP-kinase scaffold activity	5/2342	12/18639	0.416666666666667	3.31607600341588	0.0115073115694584	0.0751155664760126
GO:0016361	activin receptor activity, type I	5/2342	12/18639	0.416666666666667	3.31607600341588	0.0115073115694584	0.0751155664760126
GO:0016362	activin receptor activity, type II	5/2342	12/18639	0.416666666666667	3.31607600341588	0.0115073115694584	0.0751155664760126
GO:0017002	activin receptor activity	5/2342	12/18639	0.416666666666667	3.31607600341588	0.0115073115694584	0.0751155664760126
GO:0017166	vinculin binding	5/2342	12/18639	0.416666666666667	3.31607600341588	0.0115073115694584	0.0751155664760126
GO:0035497	cAMP response element binding	5/2342	12/18639	0.416666666666667	3.31607600341588	0.0115073115694584	0.0751155664760126
GO:0004112	cyclic-nucleotide phosphodiesterase activity	8/2342	26/18639	0.307692307692308	2.44879458713788	0.0118509049409	0.0758341158533453
GO:0005112	Notch binding	8/2342	26/18639	0.307692307692308	2.44879458713788	0.0118509049409	0.0758341158533453
GO:0005160	transforming growth factor beta receptor binding	8/2342	26/18639	0.307692307692308	2.44879458713788	0.0118509049409	0.0758341158533453
GO:0030247	polysaccharide binding	8/2342	26/18639	0.307692307692308	2.44879458713788	0.0118509049409	0.0758341158533453
GO:0140272	exogenous protein binding	18/2342	82/18639	0.219512195121951	1.74700589448251	0.0120807615751095	0.0769260259120944
GO:0023023	MHC protein complex binding	10/2342	37/18639	0.27027027027027	2.15096821843192	0.0135880709324146	0.0861019714205195
GO:0001540	amyloid-beta binding	18/2342	83/18639	0.216867469879518	1.72595763069357	0.0136641093708222	0.0861634857897962
GO:0046965	nuclear retinoid X receptor binding	6/2342	17/18639	0.352941176470588	2.80891143818757	0.0141126147221239	0.088561770647531
GO:1901981	phosphatidylinositol phosphate binding	34/2342	185/18639	0.183783783783784	1.46265838853371	0.0142271304814908	0.0888511658435412
GO:0004843	cysteine-type deubiquitinase activity	22/2342	108/18639	0.203703703703704	1.6211927127811	0.014363949090658	0.0892764108553337
GO:0120015	sterol transfer activity	9/2342	32/18639	0.28125	2.23835130230572	0.0144522061790826	0.0893972182220393
GO:0042826	histone deacetylase binding	25/2342	127/18639	0.196850393700787	1.56665008035396	0.0145362136818186	0.0894907183539447
GO:0000146	microfilament motor activity	10/2342	38/18639	0.263157894736842	2.09436379163108	0.0164169453875857	0.10012024440598
GO:0043531	ADP binding	10/2342	38/18639	0.263157894736842	2.09436379163108	0.0164169453875857	0.10012024440598
GO:0015026	coreceptor activity	14/2342	61/18639	0.229508196721311	1.8265598969635	0.0172679665674686	0.104818170893186
GO:0016248	channel inhibitor activity	11/2342	44/18639	0.25	1.98964560204953	0.0178410717236273	0.107793265902288
GO:0008083	growth factor activity	30/2342	162/18639	0.185185185185185	1.47381155707373	0.0184169218784137	0.110757321852127
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	8/2342	28/18639	0.285714285714286	2.27388068805661	0.0187763416006686	0.112398468844555
GO:0098641	cadherin binding involved in cell-cell adhesion	6/2342	18/18639	0.333333333333333	2.65286080273271	0.0189630395428018	0.112995359477521
GO:0016849	phosphorus-oxygen lyase activity	7/2342	23/18639	0.304347826086957	2.42217725466899	0.0193483075916218	0.114764619002359
GO:0035091	phosphatidylinositol binding	48/2342	284/18639	0.169014084507042	1.34511251969546	0.0194573353431264	0.114886720957823
GO:1990841	promoter-specific chromatin binding	15/2342	68/18639	0.220588235294118	1.75556964886723	0.0199270118094986	0.117127549052211
GO:0141110	transporter inhibitor activity	11/2342	45/18639	0.244444444444444	1.94543125533732	0.0210083186054924	0.122927053461868
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	9/2342	34/18639	0.264705882352941	2.10668357864068	0.0214744574654062	0.124532679676619
GO:0090482	vitamin transmembrane transporter activity	9/2342	34/18639	0.264705882352941	2.10668357864068	0.0214744574654062	0.124532679676619
GO:0001618	virus receptor activity	17/2342	81/18639	0.209876543209877	1.67031976468356	0.0220982912259232	0.12758080134433
GO:0005344	oxygen carrier activity	5/2342	14/18639	0.357142857142857	2.84235086007076	0.0234705283673494	0.131414725643047
GO:0005545	1-phosphatidylinositol binding	5/2342	14/18639	0.357142857142857	2.84235086007076	0.0234705283673494	0.131414725643047
GO:0008331	high voltage-gated calcium channel activity	5/2342	14/18639	0.357142857142857	2.84235086007076	0.0234705283673494	0.131414725643047
GO:0042043	neurexin family protein binding	5/2342	14/18639	0.357142857142857	2.84235086007076	0.0234705283673494	0.131414725643047
GO:0046030	inositol trisphosphate phosphatase activity	5/2342	14/18639	0.357142857142857	2.84235086007076	0.0234705283673494	0.131414725643047
GO:0098821	BMP receptor activity	5/2342	14/18639	0.357142857142857	2.84235086007076	0.0234705283673494	0.131414725643047
GO:1901474	azole transmembrane transporter activity	5/2342	14/18639	0.357142857142857	2.84235086007076	0.0234705283673494	0.131414725643047
GO:0060229	lipase activator activity	7/2342	24/18639	0.291666666666667	2.32125320239112	0.0244275590082568	0.136186262453758
GO:0043395	heparan sulfate proteoglycan binding	6/2342	19/18639	0.315789473684211	2.5132365499573	0.0248364951850474	0.137874389937507
GO:0030159	signaling receptor complex adaptor activity	12/2342	52/18639	0.230769230769231	1.83659594035341	0.0252965238277468	0.139830572137205
GO:0005126	cytokine receptor binding	46/2342	275/18639	0.167272727272727	1.33125378464405	0.0256808284896543	0.141290197704959
GO:0061631	ubiquitin conjugating enzyme activity	9/2342	35/18639	0.257142857142857	2.04649261925095	0.0257781192117592	0.141290197704959
GO:0001664	G protein-coupled receptor binding	49/2342	297/18639	0.164983164983165	1.31303211448387	0.0274409297241046	0.149772133242067
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	4/2342	10/18639	0.4	3.18343296327925	0.0279083691175072	0.150427267566979
GO:0031720	haptoglobin binding	4/2342	10/18639	0.4	3.18343296327925	0.0279083691175072	0.150427267566979
GO:0070513	death domain binding	4/2342	10/18639	0.4	3.18343296327925	0.0279083691175072	0.150427267566979
GO:0101005	deubiquitinase activity	22/2342	115/18639	0.191304347826087	1.52251141722051	0.0282506856083803	0.15164314299705
GO:0001784	phosphotyrosine residue binding	11/2342	47/18639	0.234042553191489	1.86264694659956	0.0285504601813702	0.151996097440983
GO:0043495	protein-membrane adaptor activity	11/2342	47/18639	0.234042553191489	1.86264694659956	0.0285504601813702	0.151996097440983
GO:0017046	peptide hormone binding	12/2342	53/18639	0.226415094339623	1.80194318676184	0.0290820953682676	0.153713153303146
GO:0045309	protein phosphorylated amino acid binding	13/2342	59/18639	0.220338983050847	1.75358595434874	0.0292279821908215	0.153713153303146
GO:0070888	E-box binding	13/2342	59/18639	0.220338983050847	1.75358595434874	0.0292279821908215	0.153713153303146
GO:0005216	monoatomic ion channel activity	70/2342	448/18639	0.15625	1.24352850128096	0.0310496468769135	0.162635045536736
GO:0005523	tropomyosin binding	5/2342	15/18639	0.333333333333333	2.65286080273271	0.0316457256048177	0.163016062981949
GO:0051371	muscle alpha-actinin binding	5/2342	15/18639	0.333333333333333	2.65286080273271	0.0316457256048177	0.163016062981949
GO:0140776	protein-containing complex destabilizing activity	5/2342	15/18639	0.333333333333333	2.65286080273271	0.0316457256048177	0.163016062981949
GO:0010851	cyclase regulator activity	6/2342	20/18639	0.3	2.38757472245944	0.0318075849575203	0.163016062981949
GO:0030742	GTP-dependent protein binding	6/2342	20/18639	0.3	2.38757472245944	0.0318075849575203	0.163016062981949
GO:0044325	transmembrane transporter binding	25/2342	136/18639	0.183823529411765	1.46297470738936	0.031875350267448	0.163016062981949
GO:0008235	metalloexopeptidase activity	14/2342	66/18639	0.212121212121212	1.68818414719354	0.0327919913945113	0.16666014258936
GO:0072341	modified amino acid binding	18/2342	91/18639	0.197802197802198	1.5742250917315	0.032873736269388	0.16666014258936
GO:0032266	phosphatidylinositol-3-phosphate binding	11/2342	48/18639	0.229166666666667	1.82384180187874	0.0329727918748772	0.16666014258936
GO:0070273	phosphatidylinositol-4-phosphate binding	8/2342	31/18639	0.258064516129032	2.05382771824468	0.0339403075436232	0.170225712351994
GO:0070325	lipoprotein particle receptor binding	8/2342	31/18639	0.258064516129032	2.05382771824468	0.0339403075436232	0.170225712351994
GO:0070006	metalloaminopeptidase activity	7/2342	26/18639	0.269230769230769	2.14269526374565	0.0371659984701827	0.185687046202951
GO:0008200	ion channel inhibitor activity	10/2342	43/18639	0.232558139534884	1.85083311818561	0.0373563970015936	0.185923217260805
GO:0035254	glutamate receptor binding	11/2342	49/18639	0.224489795918367	1.7866205406159	0.0378584912938776	0.187702977827279
GO:0002162	dystroglycan binding	4/2342	11/18639	0.363636363636364	2.8940299666175	0.0395829865158165	0.192577900689309
GO:0003953	NAD+ nucleosidase activity	4/2342	11/18639	0.363636363636364	2.8940299666175	0.0395829865158165	0.192577900689309
GO:0034056	estrogen response element binding	4/2342	11/18639	0.363636363636364	2.8940299666175	0.0395829865158165	0.192577900689309
GO:0043522	leucine zipper domain binding	4/2342	11/18639	0.363636363636364	2.8940299666175	0.0395829865158165	0.192577900689309
GO:0180030	inositol phosphate kinase activity	4/2342	11/18639	0.363636363636364	2.8940299666175	0.0395829865158165	0.192577900689309
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	5/2342	16/18639	0.3125	2.48705700256191	0.0413948350681677	0.199155150939073
GO:0030275	LRR domain binding	5/2342	16/18639	0.3125	2.48705700256191	0.0413948350681677	0.199155150939073
GO:0061809	NAD+ nucleosidase activity, cyclic ADP-ribose generating	5/2342	16/18639	0.3125	2.48705700256191	0.0413948350681677	0.199155150939073
GO:0003774	cytoskeletal motor activity	27/2342	153/18639	0.176470588235294	1.40445571909379	0.0420291016467584	0.199497294837461
GO:0030971	receptor tyrosine kinase binding	16/2342	81/18639	0.197530864197531	1.57206566087864	0.0430017263698915	0.199497294837461
GO:0033192	calmodulin-dependent protein phosphatase activity	16/2342	81/18639	0.197530864197531	1.57206566087864	0.0430017263698915	0.199497294837461
GO:0140791	histone H2AXS140 phosphatase activity	16/2342	81/18639	0.197530864197531	1.57206566087864	0.0430017263698915	0.199497294837461
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	16/2342	81/18639	0.197530864197531	1.57206566087864	0.0430017263698915	0.199497294837461
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	16/2342	81/18639	0.197530864197531	1.57206566087864	0.0430017263698915	0.199497294837461
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	16/2342	81/18639	0.197530864197531	1.57206566087864	0.0430017263698915	0.199497294837461
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	16/2342	81/18639	0.197530864197531	1.57206566087864	0.0430017263698915	0.199497294837461
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	16/2342	81/18639	0.197530864197531	1.57206566087864	0.0430017263698915	0.199497294837461
GO:1990439	MAP kinase serine/threonine phosphatase activity	16/2342	81/18639	0.197530864197531	1.57206566087864	0.0430017263698915	0.199497294837461
GO:0004683	calcium/calmodulin-dependent protein kinase activity	7/2342	27/18639	0.259259259259259	2.06333617990322	0.0449147591409172	0.207630861651429
GO:0005525	GTP binding	59/2342	378/18639	0.156084656084656	1.242212598105	0.0452962722155553	0.208651977333356
GO:0019001	guanyl nucleotide binding	62/2342	400/18639	0.155	1.23358027327071	0.0462255564955096	0.211433091153757
GO:0032561	guanyl ribonucleotide binding	62/2342	400/18639	0.155	1.23358027327071	0.0462255564955096	0.211433091153757
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	16/2342	82/18639	0.195121951219512	1.5528941284289	0.0474340817276318	0.215443608965712
GO:0033549	MAP kinase phosphatase activity	16/2342	82/18639	0.195121951219512	1.5528941284289	0.0474340817276318	0.215443608965712
GO:0031490	chromatin DNA binding	23/2342	128/18639	0.1796875	1.4300577764731	0.0480039334862621	0.217272158880329
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	9/2342	39/18639	0.230769230769231	1.83659594035341	0.049048148537452	0.221227586632466
GO:0004715	non-membrane spanning protein tyrosine kinase activity	10/2342	45/18639	0.222222222222222	1.76857386848847	0.0494070213963494	0.222075158456255
GO:0008238	exopeptidase activity	19/2342	102/18639	0.186274509803922	1.48248103682122	0.0498505261210666	0.223295977349191
GO:0004620	phospholipase activity	20/2342	109/18639	0.18348623853211	1.4602903501281	0.0516125663871089	0.230394239645548
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	16/2342	83/18639	0.192771084337349	1.53418456061651	0.0521788076624415	0.232124216279149
GO:0008484	sulfuric ester hydrolase activity	5/2342	17/18639	0.294117647058824	2.34075953182298	0.0527624268790192	0.233123784067503
GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	5/2342	17/18639	0.294117647058824	2.34075953182298	0.0527624268790192	0.233123784067503
GO:0004000	adenosine deaminase activity	4/2342	12/18639	0.333333333333333	2.65286080273271	0.0536208239889956	0.234552885249088
GO:0008179	adenylate cyclase binding	4/2342	12/18639	0.333333333333333	2.65286080273271	0.0536208239889956	0.234552885249088
GO:0051019	mitogen-activated protein kinase binding	7/2342	28/18639	0.25	1.98964560204953	0.0536275649876668	0.234552885249088
GO:0019825	oxygen binding	8/2342	34/18639	0.235294117647059	1.87260762545838	0.0557802101607346	0.241528309995981
GO:0051427	hormone receptor binding	8/2342	34/18639	0.235294117647059	1.87260762545838	0.0557802101607346	0.241528309995981
GO:0052866	phosphatidylinositol phosphate phosphatase activity	8/2342	34/18639	0.235294117647059	1.87260762545838	0.0557802101607346	0.241528309995981
GO:0030331	nuclear estrogen receptor binding	9/2342	40/18639	0.225	1.79068104184458	0.0565102638237481	0.243876520621425
GO:0008017	microtubule binding	44/2342	276/18639	0.159420289855072	1.26875951435043	0.0567289916848516	0.244009801982193
GO:0017018	myosin phosphatase activity	16/2342	84/18639	0.19047619047619	1.5159204587044	0.0572442160760216	0.245370025753521
GO:0019208	phosphatase regulator activity	21/2342	117/18639	0.179487179487179	1.42846350916377	0.0574230083364668	0.245370025753521
GO:0120013	lipid transfer activity	13/2342	65/18639	0.2	1.59171648163962	0.0586521796820585	0.24980059477703
GO:0031072	heat shock protein binding	23/2342	131/18639	0.175572519083969	1.39730836174471	0.0598338326064536	0.254000485476416
GO:1902936	phosphatidylinositol bisphosphate binding	20/2342	111/18639	0.18018018018018	1.43397881228795	0.0604931021301073	0.255722880379049
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	12/2342	59/18639	0.203389830508475	1.61869472709114	0.060633292653385	0.255722880379049
GO:0051018	protein kinase A binding	11/2342	53/18639	0.207547169811321	1.65178125453169	0.0623963004000692	0.261460626515129
GO:0140296	general transcription initiation factor binding	11/2342	53/18639	0.207547169811321	1.65178125453169	0.0623963004000692	0.261460626515129
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	7/2342	29/18639	0.241379310344828	1.92103713301334	0.0633253233586387	0.264500305604089
GO:0140359	ABC-type transporter activity	10/2342	47/18639	0.212765957446809	1.6933154059996	0.0638077461357784	0.265661096892231
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	9/2342	41/18639	0.219512195121951	1.74700589448251	0.0646678776233404	0.265834091875694
GO:0017080	sodium channel regulator activity	9/2342	41/18639	0.219512195121951	1.74700589448251	0.0646678776233404	0.265834091875694
GO:0042169	SH2 domain binding	9/2342	41/18639	0.219512195121951	1.74700589448251	0.0646678776233404	0.265834091875694
GO:0061650	ubiquitin-like protein conjugating enzyme activity	9/2342	41/18639	0.219512195121951	1.74700589448251	0.0646678776233404	0.265834091875694
GO:0070851	growth factor receptor binding	24/2342	139/18639	0.172661870503597	1.37414372515651	0.0650823581789849	0.266121764547024
GO:0004706	JUN kinase kinase kinase activity	5/2342	18/18639	0.277777777777778	2.21071733561059	0.0657621912391029	0.266121764547024
GO:0035615	clathrin adaptor activity	5/2342	18/18639	0.277777777777778	2.21071733561059	0.0657621912391029	0.266121764547024
GO:0052744	phosphatidylinositol monophosphate phosphatase activity	5/2342	18/18639	0.277777777777778	2.21071733561059	0.0657621912391029	0.266121764547024
GO:0070064	proline-rich region binding	5/2342	18/18639	0.277777777777778	2.21071733561059	0.0657621912391029	0.266121764547024
GO:0099106	ion channel regulator activity	27/2342	160/18639	0.16875	1.34301078138343	0.0669345064594237	0.270024608356495
GO:0045159	myosin II binding	4/2342	13/18639	0.307692307692308	2.44879458713788	0.0699886294756986	0.28060256076831
GO:0061459	L-arginine transmembrane transporter activity	4/2342	13/18639	0.307692307692308	2.44879458713788	0.0699886294756986	0.28060256076831
GO:0051219	phosphoprotein binding	17/2342	93/18639	0.182795698924731	1.45479463375665	0.0706919873300348	0.28255043551297
GO:0016247	channel regulator activity	28/2342	168/18639	0.166666666666667	1.32643040136635	0.0715065354892724	0.284529341883498
GO:0070300	phosphatidic acid binding	6/2342	24/18639	0.25	1.98964560204953	0.0716251692039289	0.284529341883498
GO:0019783	ubiquitin-like protein peptidase activity	22/2342	127/18639	0.173228346456693	1.37865207071149	0.0727017163055116	0.287925394758718
GO:0008307	structural constituent of muscle	9/2342	42/18639	0.214285714285714	1.70541051604245	0.0735316966825177	0.290327276567144
GO:0035925	mRNA 3'-UTR AU-rich region binding	7/2342	30/18639	0.233333333333333	1.8570025619129	0.0740187315476429	0.291052459117461
GO:0019888	protein phosphatase regulator activity	19/2342	107/18639	0.177570093457944	1.41320622201649	0.0743244064750689	0.291052459117461
GO:0004869	cysteine-type endopeptidase inhibitor activity	8/2342	36/18639	0.222222222222222	1.76857386848847	0.0743875415142393	0.291052459117461
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	5/2342	19/18639	0.263157894736842	2.09436379163108	0.0803785112584083	0.310678443932638
GO:0046624	sphingolipid transporter activity	5/2342	19/18639	0.263157894736842	2.09436379163108	0.0803785112584083	0.310678443932638
GO:1990380	K48-linked deubiquitinase activity	5/2342	19/18639	0.263157894736842	2.09436379163108	0.0803785112584083	0.310678443932638
GO:0141108	transporter regulator activity	28/2342	170/18639	0.164705882352941	1.31082533782087	0.0803943884851023	0.310678443932638
GO:0015631	tubulin binding	58/2342	385/18639	0.150649350649351	1.19895527188439	0.0805994115514233	0.310678443932638
GO:0004709	MAP kinase kinase kinase activity	6/2342	25/18639	0.24	1.91005977796755	0.0846593079948081	0.320619361764594
GO:0015271	outward rectifier potassium channel activity	6/2342	25/18639	0.24	1.91005977796755	0.0846593079948081	0.320619361764594
GO:0015645	fatty acid ligase activity	6/2342	25/18639	0.24	1.91005977796755	0.0846593079948081	0.320619361764594
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	6/2342	25/18639	0.24	1.91005977796755	0.0846593079948081	0.320619361764594
GO:0120020	cholesterol transfer activity	6/2342	25/18639	0.24	1.91005977796755	0.0846593079948081	0.320619361764594
GO:0120515	fatty acid-CoA ligase activity	6/2342	25/18639	0.24	1.91005977796755	0.0846593079948081	0.320619361764594
GO:0170055	lipid transmembrane transporter activity	11/2342	56/18639	0.196428571428571	1.56329297303892	0.0864011857314549	0.326264942631279
GO:0004065	arylsulfatase activity	4/2342	14/18639	0.285714285714286	2.27388068805661	0.0885958699190383	0.329554524689959
GO:0008559	ABC-type xenobiotic transporter activity	4/2342	14/18639	0.285714285714286	2.27388068805661	0.0885958699190383	0.329554524689959
GO:0019992	diacylglycerol binding	4/2342	14/18639	0.285714285714286	2.27388068805661	0.0885958699190383	0.329554524689959
GO:0043176	amine binding	4/2342	14/18639	0.285714285714286	2.27388068805661	0.0885958699190383	0.329554524689959
GO:0071933	Arp2/3 complex binding	4/2342	14/18639	0.285714285714286	2.27388068805661	0.0885958699190383	0.329554524689959
GO:0016298	lipase activity	22/2342	130/18639	0.169230769230769	1.34683702292584	0.0887945216639612	0.329554524689959
GO:0005253	monoatomic anion channel activity	18/2342	103/18639	0.174757281553398	1.3908202266754	0.0910829032818635	0.337084590778178
GO:0001046	core promoter sequence-specific DNA binding	9/2342	44/18639	0.204545454545455	1.62789185622234	0.0933961345825107	0.3446635762008
GO:0005262	calcium channel activity	22/2342	131/18639	0.16793893129771	1.33655582427755	0.0946397983544675	0.347585176387838
GO:0019210	kinase inhibitor activity	16/2342	90/18639	0.177777777777778	1.41485909479078	0.0947229810941451	0.347585176387838
GO:0046906	tetrapyrrole binding	25/2342	152/18639	0.164473684210526	1.30897736976943	0.0953835067796286	0.349023029033064
GO:0016004	phospholipase activator activity	5/2342	20/18639	0.25	1.98964560204953	0.0965688200253711	0.351380664462065
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	5/2342	20/18639	0.25	1.98964560204953	0.0965688200253711	0.351380664462065
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	6/2342	26/18639	0.230769230769231	1.83659594035341	0.0989073008521957	0.358884312310062
GO:0004860	protein kinase inhibitor activity	15/2342	84/18639	0.178571428571429	1.42117543003538	0.100251304284982	0.362747755616133
GO:0042605	peptide antigen binding	9/2342	45/18639	0.2	1.59171648163962	0.104393412879051	0.376686231471909
GO:0015085	calcium ion transmembrane transporter activity	24/2342	147/18639	0.163265306122449	1.2993603931752	0.107079815776598	0.385309364802772
GO:0033218	amide binding	38/2342	247/18639	0.153846153846154	1.22439729356894	0.107831091037922	0.386886137015067
GO:0016776	phosphotransferase activity, phosphate group as acceptor	8/2342	39/18639	0.205128205128205	1.63252972475859	0.108514877040069	0.386886137015067
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	4/2342	15/18639	0.266666666666667	2.12228864218617	0.109305013306028	0.386886137015067
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	4/2342	15/18639	0.266666666666667	2.12228864218617	0.109305013306028	0.386886137015067
GO:0050700	CARD domain binding	4/2342	15/18639	0.266666666666667	2.12228864218617	0.109305013306028	0.386886137015067
GO:0120283	protein serine/threonine kinase binding	4/2342	15/18639	0.266666666666667	2.12228864218617	0.109305013306028	0.386886137015067
GO:0019239	deaminase activity	7/2342	33/18639	0.212121212121212	1.68818414719354	0.112027989690216	0.392908809529447
GO:0140416	transcription regulator inhibitor activity	7/2342	33/18639	0.212121212121212	1.68818414719354	0.112027989690216	0.392908809529447
GO:0005248	voltage-gated sodium channel activity	5/2342	21/18639	0.238095238095238	1.8949005733805	0.114266508364144	0.392908809529447
GO:0009931	calcium-dependent protein serine/threonine kinase activity	5/2342	21/18639	0.238095238095238	1.8949005733805	0.114266508364144	0.392908809529447
GO:0010314	phosphatidylinositol-5-phosphate binding	5/2342	21/18639	0.238095238095238	1.8949005733805	0.114266508364144	0.392908809529447
GO:0015174	basic amino acid transmembrane transporter activity	5/2342	21/18639	0.238095238095238	1.8949005733805	0.114266508364144	0.392908809529447
GO:0036122	BMP binding	5/2342	21/18639	0.238095238095238	1.8949005733805	0.114266508364144	0.392908809529447
GO:0051428	peptide hormone receptor binding	5/2342	21/18639	0.238095238095238	1.8949005733805	0.114266508364144	0.392908809529447
GO:0140312	cargo adaptor activity	5/2342	21/18639	0.238095238095238	1.8949005733805	0.114266508364144	0.392908809529447
GO:0016405	CoA-ligase activity	6/2342	27/18639	0.222222222222222	1.76857386848847	0.114333741341132	0.392908809529447
GO:0034593	phosphatidylinositol bisphosphate phosphatase activity	6/2342	27/18639	0.222222222222222	1.76857386848847	0.114333741341132	0.392908809529447
GO:0004180	carboxypeptidase activity	9/2342	46/18639	0.195652173913043	1.55711394943007	0.11609030348762	0.395560327531044
GO:0030276	clathrin binding	9/2342	46/18639	0.195652173913043	1.55711394943007	0.11609030348762	0.395560327531044
GO:0030291	protein serine/threonine kinase inhibitor activity	9/2342	46/18639	0.195652173913043	1.55711394943007	0.11609030348762	0.395560327531044
GO:0004382	GDP phosphatase activity	3/2342	10/18639	0.3	2.38757472245944	0.1208910315857	0.395560327531044
GO:0004862	cAMP-dependent protein kinase inhibitor activity	3/2342	10/18639	0.3	2.38757472245944	0.1208910315857	0.395560327531044
GO:0004955	prostaglandin receptor activity	3/2342	10/18639	0.3	2.38757472245944	0.1208910315857	0.395560327531044
GO:0005131	growth hormone receptor binding	3/2342	10/18639	0.3	2.38757472245944	0.1208910315857	0.395560327531044
GO:0030957	Tat protein binding	3/2342	10/18639	0.3	2.38757472245944	0.1208910315857	0.395560327531044
GO:0031078	histone H3K14 deacetylase activity, hydrolytic mechanism	3/2342	10/18639	0.3	2.38757472245944	0.1208910315857	0.395560327531044
GO:0031419	cobalamin binding	3/2342	10/18639	0.3	2.38757472245944	0.1208910315857	0.395560327531044
GO:0031434	mitogen-activated protein kinase kinase binding	3/2342	10/18639	0.3	2.38757472245944	0.1208910315857	0.395560327531044
GO:0031956	medium-chain fatty acid-CoA ligase activity	3/2342	10/18639	0.3	2.38757472245944	0.1208910315857	0.395560327531044
GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity	3/2342	10/18639	0.3	2.38757472245944	0.1208910315857	0.395560327531044
GO:0034739	histone H4K16 deacetylase activity, hydrolytic mechanism	3/2342	10/18639	0.3	2.38757472245944	0.1208910315857	0.395560327531044
GO:0035256	G protein-coupled glutamate receptor binding	3/2342	10/18639	0.3	2.38757472245944	0.1208910315857	0.395560327531044
GO:0035374	chondroitin sulfate binding	3/2342	10/18639	0.3	2.38757472245944	0.1208910315857	0.395560327531044
GO:0180032	histone H4K5 deacetylase activity, hydrolytic mechanism	3/2342	10/18639	0.3	2.38757472245944	0.1208910315857	0.395560327531044
GO:0180033	histone H4K8 deacetylase activity, hydrolytic mechanism	3/2342	10/18639	0.3	2.38757472245944	0.1208910315857	0.395560327531044
GO:1990162	histone H3K4 deacetylase activity, hydrolytic mechanism	3/2342	10/18639	0.3	2.38757472245944	0.1208910315857	0.395560327531044
GO:0004177	aminopeptidase activity	8/2342	40/18639	0.2	1.59171648163962	0.12151603034415	0.395612339391103
GO:0071949	FAD binding	8/2342	40/18639	0.2	1.59171648163962	0.12151603034415	0.395612339391103
GO:0003924	GTPase activity	49/2342	331/18639	0.148036253776435	1.17815872508069	0.124969658762643	0.405838966831684
GO:0008376	acetylgalactosaminyltransferase activity	7/2342	34/18639	0.205882352941176	1.63853167227608	0.126610747346007	0.409435187760215
GO:0030246	carbohydrate binding	42/2342	280/18639	0.15	1.19378736122972	0.126707425311475	0.409435187760215
GO:0022843	voltage-gated monoatomic cation channel activity	23/2342	143/18639	0.160839160839161	1.28005171600389	0.1270451523334	0.409507823526269
GO:0050698	proteoglycan sulfotransferase activity	6/2342	28/18639	0.214285714285714	1.70541051604245	0.130889971255714	0.414993509592066
GO:0141052	histone H3 demethylase activity	6/2342	28/18639	0.214285714285714	1.70541051604245	0.130889971255714	0.414993509592066
GO:0005324	long-chain fatty acid transmembrane transporter activity	4/2342	16/18639	0.25	1.98964560204953	0.131941739385314	0.414993509592066
GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	4/2342	16/18639	0.25	1.98964560204953	0.131941739385314	0.414993509592066
GO:0016722	oxidoreductase activity, acting on metal ions	4/2342	16/18639	0.25	1.98964560204953	0.131941739385314	0.414993509592066
GO:0022841	potassium ion leak channel activity	4/2342	16/18639	0.25	1.98964560204953	0.131941739385314	0.414993509592066
GO:0031435	mitogen-activated protein kinase kinase kinase binding	4/2342	16/18639	0.25	1.98964560204953	0.131941739385314	0.414993509592066
GO:0034450	ubiquitin-ubiquitin ligase activity	4/2342	16/18639	0.25	1.98964560204953	0.131941739385314	0.414993509592066
GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	4/2342	16/18639	0.25	1.98964560204953	0.131941739385314	0.414993509592066
GO:0055102	lipase inhibitor activity	4/2342	16/18639	0.25	1.98964560204953	0.131941739385314	0.414993509592066
GO:0050321	tau-protein kinase activity	5/2342	22/18639	0.227272727272727	1.80876872913594	0.133384178615939	0.418517024207983
GO:0008234	cysteine-type peptidase activity	29/2342	187/18639	0.155080213903743	1.23421866223393	0.134603667072634	0.421325695246631
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	21/2342	130/18639	0.161538461538462	1.28561715824739	0.13540814780122	0.422824961523521
GO:0005261	monoatomic cation channel activity	50/2342	341/18639	0.146627565982405	1.16694756718448	0.136993321796179	0.426748980847091
GO:0005267	potassium channel activity	20/2342	124/18639	0.161290322580645	1.28364232390292	0.143873779487171	0.44711014247329
GO:0004722	protein serine/threonine phosphatase activity	17/2342	103/18639	0.16504854368932	1.31355243630454	0.144893888813159	0.449033590378584
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	6/2342	29/18639	0.206896551724138	1.64660325686858	0.14851553157669	0.449033590378584
GO:0043236	laminin binding	6/2342	29/18639	0.206896551724138	1.64660325686858	0.14851553157669	0.449033590378584
GO:0097472	cyclin-dependent protein kinase activity	6/2342	29/18639	0.206896551724138	1.64660325686858	0.14851553157669	0.449033590378584
GO:0022832	voltage-gated channel activity	27/2342	175/18639	0.154285714285714	1.22789557155057	0.150772790940048	0.449033590378584
GO:0001161	intronic transcription regulatory region sequence-specific DNA binding	3/2342	11/18639	0.272727272727273	2.17052247496312	0.151381548486907	0.449033590378584
GO:0004117	calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity	3/2342	11/18639	0.272727272727273	2.17052247496312	0.151381548486907	0.449033590378584
GO:0004954	prostanoid receptor activity	3/2342	11/18639	0.272727272727273	2.17052247496312	0.151381548486907	0.449033590378584
GO:0005225	volume-sensitive anion channel activity	3/2342	11/18639	0.272727272727273	2.17052247496312	0.151381548486907	0.449033590378584
GO:0005536	D-glucose binding	3/2342	11/18639	0.272727272727273	2.17052247496312	0.151381548486907	0.449033590378584
GO:0008432	JUN kinase binding	3/2342	11/18639	0.272727272727273	2.17052247496312	0.151381548486907	0.449033590378584
GO:0019206	nucleoside kinase activity	3/2342	11/18639	0.272727272727273	2.17052247496312	0.151381548486907	0.449033590378584
GO:0032129	histone H3K9 deacetylase activity, hydrolytic mechanism	3/2342	11/18639	0.272727272727273	2.17052247496312	0.151381548486907	0.449033590378584
GO:0034713	type I transforming growth factor beta receptor binding	3/2342	11/18639	0.272727272727273	2.17052247496312	0.151381548486907	0.449033590378584
GO:0042608	T cell receptor binding	3/2342	11/18639	0.272727272727273	2.17052247496312	0.151381548486907	0.449033590378584
GO:0048101	calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity	3/2342	11/18639	0.272727272727273	2.17052247496312	0.151381548486907	0.449033590378584
GO:0048407	platelet-derived growth factor binding	3/2342	11/18639	0.272727272727273	2.17052247496312	0.151381548486907	0.449033590378584
GO:0140031	phosphorylation-dependent protein binding	3/2342	11/18639	0.272727272727273	2.17052247496312	0.151381548486907	0.449033590378584
GO:0140937	histone H4K12 deacetylase activity, hydrolytic mechanism	3/2342	11/18639	0.272727272727273	2.17052247496312	0.151381548486907	0.449033590378584
GO:0002039	p53 binding	12/2342	69/18639	0.173913043478261	1.38410128838228	0.151406245254673	0.449033590378584
GO:0005254	chloride channel activity	14/2342	83/18639	0.168674698795181	1.34241149053944	0.153785839405181	0.453080215430097
GO:0031681	G-protein beta-subunit binding	5/2342	23/18639	0.217391304347826	1.73012661047785	0.153817070827308	0.453080215430097
GO:0043274	phospholipase binding	5/2342	23/18639	0.217391304347826	1.73012661047785	0.153817070827308	0.453080215430097
GO:0004029	aldehyde dehydrogenase (NAD+) activity	4/2342	17/18639	0.235294117647059	1.87260762545838	0.156304604771867	0.455245922866939
GO:0004438	phosphatidylinositol-3-phosphate phosphatase activity	4/2342	17/18639	0.235294117647059	1.87260762545838	0.156304604771867	0.455245922866939
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	4/2342	17/18639	0.235294117647059	1.87260762545838	0.156304604771867	0.455245922866939
GO:0008429	phosphatidylethanolamine binding	4/2342	17/18639	0.235294117647059	1.87260762545838	0.156304604771867	0.455245922866939
GO:1990226	histone methyltransferase binding	4/2342	17/18639	0.235294117647059	1.87260762545838	0.156304604771867	0.455245922866939
GO:0004712	protein serine/threonine/tyrosine kinase activity	8/2342	43/18639	0.186046511627907	1.48066649454849	0.165081478094138	0.477596525711102
GO:0008375	acetylglucosaminyltransferase activity	8/2342	43/18639	0.186046511627907	1.48066649454849	0.165081478094138	0.477596525711102
GO:0048156	tau protein binding	8/2342	43/18639	0.186046511627907	1.48066649454849	0.165081478094138	0.477596525711102
GO:0022839	monoatomic ion-gated channel activity	6/2342	30/18639	0.2	1.59171648163962	0.167139731583952	0.480341839220251
GO:0032452	histone demethylase activity	6/2342	30/18639	0.2	1.59171648163962	0.167139731583952	0.480341839220251
GO:0051721	protein phosphatase 2A binding	6/2342	30/18639	0.2	1.59171648163962	0.167139731583952	0.480341839220251
GO:0004601	peroxidase activity	10/2342	57/18639	0.175438596491228	1.39624252775406	0.172452049733339	0.493425578422042
GO:0016504	peptidase activator activity	10/2342	57/18639	0.175438596491228	1.39624252775406	0.172452049733339	0.493425578422042
GO:0020037	heme binding	22/2342	142/18639	0.154929577464789	1.23301980972084	0.174932435743792	0.496525114795624
GO:0001091	RNA polymerase II general transcription initiation factor binding	5/2342	24/18639	0.208333333333333	1.65803800170794	0.175446518622934	0.496525114795624
GO:0019957	C-C chemokine binding	5/2342	24/18639	0.208333333333333	1.65803800170794	0.175446518622934	0.496525114795624
GO:0030552	cAMP binding	5/2342	24/18639	0.208333333333333	1.65803800170794	0.175446518622934	0.496525114795624
GO:0050699	WW domain binding	5/2342	24/18639	0.208333333333333	1.65803800170794	0.175446518622934	0.496525114795624
GO:0000400	four-way junction DNA binding	4/2342	18/18639	0.222222222222222	1.76857386848847	0.182173865781228	0.503314251425592
GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity	4/2342	18/18639	0.222222222222222	1.76857386848847	0.182173865781228	0.503314251425592
GO:0017128	phospholipid scramblase activity	4/2342	18/18639	0.222222222222222	1.76857386848847	0.182173865781228	0.503314251425592
GO:0031690	adrenergic receptor binding	4/2342	18/18639	0.222222222222222	1.76857386848847	0.182173865781228	0.503314251425592
GO:0005165	neurotrophin receptor binding	3/2342	12/18639	0.25	1.98964560204953	0.183968456652877	0.503314251425592
GO:0005527	macrolide binding	3/2342	12/18639	0.25	1.98964560204953	0.183968456652877	0.503314251425592
GO:0008603	cAMP-dependent protein kinase regulator activity	3/2342	12/18639	0.25	1.98964560204953	0.183968456652877	0.503314251425592
GO:0015166	polyol transmembrane transporter activity	3/2342	12/18639	0.25	1.98964560204953	0.183968456652877	0.503314251425592
GO:0015368	calcium:monoatomic cation antiporter activity	3/2342	12/18639	0.25	1.98964560204953	0.183968456652877	0.503314251425592
GO:0042301	phosphate ion binding	3/2342	12/18639	0.25	1.98964560204953	0.183968456652877	0.503314251425592
GO:0045295	gamma-catenin binding	3/2342	12/18639	0.25	1.98964560204953	0.183968456652877	0.503314251425592
GO:0070679	inositol 1,4,5 trisphosphate binding	3/2342	12/18639	0.25	1.98964560204953	0.183968456652877	0.503314251425592
GO:0097677	STAT family protein binding	3/2342	12/18639	0.25	1.98964560204953	0.183968456652877	0.503314251425592
GO:0141221	histone deacetylase activity, hydrolytic mechanism	3/2342	12/18639	0.25	1.98964560204953	0.183968456652877	0.503314251425592
GO:1902282	voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	3/2342	12/18639	0.25	1.98964560204953	0.183968456652877	0.503314251425592
GO:0005048	signal sequence binding	9/2342	51/18639	0.176470588235294	1.40445571909379	0.184432319998908	0.503314251425592
GO:0016597	amino acid binding	9/2342	51/18639	0.176470588235294	1.40445571909379	0.184432319998908	0.503314251425592
GO:0016878	acid-thiol ligase activity	6/2342	31/18639	0.193548387096774	1.54037078868351	0.186683281912384	0.507147077761883
GO:0140457	protein demethylase activity	6/2342	31/18639	0.193548387096774	1.54037078868351	0.186683281912384	0.507147077761883
GO:0016209	antioxidant activity	14/2342	86/18639	0.162790697674419	1.29558318272993	0.187008044840602	0.507147077761883
GO:0005244	voltage-gated monoatomic ion channel activity	26/2342	173/18639	0.15028901734104	1.19608752955579	0.190886164184155	0.516585681823369
GO:0005501	retinoid binding	7/2342	38/18639	0.184210526315789	1.46605465414176	0.193490295110553	0.521460359644415
GO:0019840	isoprenoid binding	7/2342	38/18639	0.184210526315789	1.46605465414176	0.193490295110553	0.521460359644415
GO:0046873	metal ion transmembrane transporter activity	63/2342	450/18639	0.14	1.11420153714774	0.19423875373461	0.522393666876312
GO:0000030	mannosyltransferase activity	5/2342	25/18639	0.2	1.59171648163962	0.198143321279965	0.52851781179194
GO:0003707	nuclear steroid receptor activity	5/2342	25/18639	0.2	1.59171648163962	0.198143321279965	0.52851781179194
GO:0005251	delayed rectifier potassium channel activity	5/2342	25/18639	0.2	1.59171648163962	0.198143321279965	0.52851781179194
GO:0008139	nuclear localization sequence binding	5/2342	25/18639	0.2	1.59171648163962	0.198143321279965	0.52851781179194
GO:0005080	protein kinase C binding	9/2342	52/18639	0.173076923076923	1.37744695526506	0.199887354110166	0.532077198748166
GO:0015459	potassium channel regulator activity	10/2342	59/18639	0.169491525423729	1.34891227257595	0.20098172345628	0.533896234702879
GO:0042910	xenobiotic transmembrane transporter activity	6/2342	32/18639	0.1875	1.49223420153715	0.207059944099186	0.546688754847241
GO:0071813	lipoprotein particle binding	6/2342	32/18639	0.1875	1.49223420153715	0.207059944099186	0.546688754847241
GO:0071814	protein-lipid complex binding	6/2342	32/18639	0.1875	1.49223420153715	0.207059944099186	0.546688754847241
GO:0015245	fatty acid transmembrane transporter activity	4/2342	19/18639	0.210526315789474	1.67549103330487	0.20931929365398	0.547094089449738
GO:0016918	retinal binding	4/2342	19/18639	0.210526315789474	1.67549103330487	0.20931929365398	0.547094089449738
GO:0022840	leak channel activity	4/2342	19/18639	0.210526315789474	1.67549103330487	0.20931929365398	0.547094089449738
GO:0022842	narrow pore channel activity	4/2342	19/18639	0.210526315789474	1.67549103330487	0.20931929365398	0.547094089449738
GO:0031420	alkali metal ion binding	4/2342	19/18639	0.210526315789474	1.67549103330487	0.20931929365398	0.547094089449738
GO:0015101	organic cation transmembrane transporter activity	13/2342	81/18639	0.160493827160494	1.2773033494639	0.212687738762478	0.554781872796103
GO:0005544	calcium-dependent phospholipid binding	9/2342	53/18639	0.169811320754717	1.35145739007138	0.215859806106315	0.561927631527262
GO:0005172	vascular endothelial growth factor receptor binding	3/2342	13/18639	0.230769230769231	1.83659594035341	0.21816240480603	0.565654618449169
GO:0031432	titin binding	3/2342	13/18639	0.230769230769231	1.83659594035341	0.21816240480603	0.565654618449169
GO:0008143	poly(A) binding	5/2342	26/18639	0.192307692307692	1.53049661696118	0.221770945191339	0.572724568197912
GO:0052742	phosphatidylinositol kinase activity	5/2342	26/18639	0.192307692307692	1.53049661696118	0.221770945191339	0.572724568197912
GO:0003725	double-stranded RNA binding	12/2342	75/18639	0.16	1.2733731853117	0.227925879392146	0.584622139824257
GO:0019003	GDP binding	12/2342	75/18639	0.16	1.2733731853117	0.227925879392146	0.584622139824257
GO:0044183	protein folding chaperone	12/2342	75/18639	0.16	1.2733731853117	0.227925879392146	0.584622139824257
GO:0019956	chemokine binding	6/2342	33/18639	0.181818181818182	1.44701498330875	0.228178156190068	0.584622139824257
GO:0003925	G protein activity	9/2342	54/18639	0.166666666666667	1.32643040136635	0.232310436690329	0.594037907993579
GO:0001972	retinoic acid binding	4/2342	20/18639	0.2	1.59171648163962	0.237506912061132	0.604663732183978
GO:0015095	magnesium ion transmembrane transporter activity	4/2342	20/18639	0.2	1.59171648163962	0.237506912061132	0.604663732183978
GO:0051087	protein-folding chaperone binding	20/2342	134/18639	0.149253731343284	1.18784812062659	0.237862330366446	0.604663732183978
GO:0004175	endopeptidase activity	56/2342	405/18639	0.138271604938272	1.10044596261505	0.23939728128058	0.607377086686473
GO:0017022	myosin binding	12/2342	76/18639	0.157894736842105	1.25661827497865	0.24199597881572	0.612773443433958
GO:0005249	voltage-gated potassium channel activity	15/2342	98/18639	0.153061224489796	1.21815036860175	0.245401615451292	0.620188129321455
GO:0035255	ionotropic glutamate receptor binding	5/2342	27/18639	0.185185185185185	1.47381155707373	0.246188491520932	0.620968641719787
GO:0016879	ligase activity, forming carbon-nitrogen bonds	8/2342	48/18639	0.166666666666667	1.32643040136635	0.250607995680299	0.62962687097653
GO:0140828	metal cation:monoatomic cation antiporter activity	7/2342	41/18639	0.170731707317073	1.35878236237529	0.251051884976344	0.62962687097653
GO:0004705	JUN kinase activity	3/2342	14/18639	0.214285714285714	1.70541051604245	0.253498732502483	0.62962687097653
GO:0032454	histone H3K9 demethylase activity	3/2342	14/18639	0.214285714285714	1.70541051604245	0.253498732502483	0.62962687097653
GO:0042813	Wnt receptor activity	3/2342	14/18639	0.214285714285714	1.70541051604245	0.253498732502483	0.62962687097653
GO:0044548	S100 protein binding	3/2342	14/18639	0.214285714285714	1.70541051604245	0.253498732502483	0.62962687097653
GO:0052816	long-chain fatty acyl-CoA hydrolase activity	3/2342	14/18639	0.214285714285714	1.70541051604245	0.253498732502483	0.62962687097653
GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization	3/2342	14/18639	0.214285714285714	1.70541051604245	0.253498732502483	0.62962687097653
GO:0016782	transferase activity, transferring sulphur-containing groups	11/2342	70/18639	0.157142857142857	1.25063437843113	0.259930528469683	0.644369764278853
GO:0030170	pyridoxal phosphate binding	9/2342	56/18639	0.160714285714286	1.27905788703184	0.266478817535397	0.654422581636331
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	4/2342	21/18639	0.19047619047619	1.5159204587044	0.266504654107482	0.654422581636331
GO:0005123	death receptor binding	4/2342	21/18639	0.19047619047619	1.5159204587044	0.266504654107482	0.654422581636331
GO:0008373	sialyltransferase activity	4/2342	21/18639	0.19047619047619	1.5159204587044	0.266504654107482	0.654422581636331
GO:0051010	microtubule plus-end binding	4/2342	21/18639	0.19047619047619	1.5159204587044	0.266504654107482	0.654422581636331
GO:0016758	hexosyltransferase activity	28/2342	197/18639	0.142131979695431	1.13116907324643	0.270735790945266	0.661084709217185
GO:0043130	ubiquitin binding	15/2342	100/18639	0.15	1.19378736122972	0.271003978433155	0.661084709217185
GO:0045499	chemorepellent activity	5/2342	28/18639	0.178571428571429	1.42117543003538	0.271253387230762	0.661084709217185
GO:0046875	ephrin receptor binding	5/2342	28/18639	0.178571428571429	1.42117543003538	0.271253387230762	0.661084709217185
GO:0004842	ubiquitin-protein transferase activity	61/2342	449/18639	0.135857461024499	1.08123279933204	0.274389915398329	0.667476591952114
GO:0008194	UDP-glycosyltransferase activity	21/2342	145/18639	0.144827586206897	1.152622279808	0.276169940823911	0.669906859699588
GO:0015079	potassium ion transmembrane transporter activity	23/2342	160/18639	0.14375	1.14404622117848	0.276420382447251	0.669906859699588
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	13/2342	86/18639	0.151162790697674	1.20304152682065	0.280875145333481	0.672904157415607
GO:0070279	vitamin B6 binding	9/2342	57/18639	0.157894736842105	1.25661827497865	0.284108836498283	0.672904157415607
GO:0016757	glycosyltransferase activity	37/2342	267/18639	0.138576779026217	1.10287471574281	0.286204231923997	0.672904157415607
GO:0032813	tumor necrosis factor receptor superfamily binding	8/2342	50/18639	0.16	1.2733731853117	0.28820906852943	0.672904157415607
GO:0048020	CCR chemokine receptor binding	8/2342	50/18639	0.16	1.2733731853117	0.28820906852943	0.672904157415607
GO:0000774	adenyl-nucleotide exchange factor activity	3/2342	15/18639	0.2	1.59171648163962	0.289547162301596	0.672904157415607
GO:0004089	carbonate dehydratase activity	3/2342	15/18639	0.2	1.59171648163962	0.289547162301596	0.672904157415607
GO:0004467	long-chain fatty acid-CoA ligase activity	3/2342	15/18639	0.2	1.59171648163962	0.289547162301596	0.672904157415607
GO:0004953	icosanoid receptor activity	3/2342	15/18639	0.2	1.59171648163962	0.289547162301596	0.672904157415607
GO:0010181	FMN binding	3/2342	15/18639	0.2	1.59171648163962	0.289547162301596	0.672904157415607
GO:0030553	cGMP binding	3/2342	15/18639	0.2	1.59171648163962	0.289547162301596	0.672904157415607
GO:0033130	acetylcholine receptor binding	3/2342	15/18639	0.2	1.59171648163962	0.289547162301596	0.672904157415607
GO:0047372	monoacylglycerol lipase activity	3/2342	15/18639	0.2	1.59171648163962	0.289547162301596	0.672904157415607
GO:0050780	dopamine receptor binding	3/2342	15/18639	0.2	1.59171648163962	0.289547162301596	0.672904157415607
GO:0141050	histone H3K deacetylase activity	3/2342	15/18639	0.2	1.59171648163962	0.289547162301596	0.672904157415607
GO:0141051	histone H4K deacetylase activity	3/2342	15/18639	0.2	1.59171648163962	0.289547162301596	0.672904157415607
GO:0016410	N-acyltransferase activity	14/2342	94/18639	0.148936170212766	1.18532078419972	0.289619375076668	0.672904157415607
GO:0005245	voltage-gated calcium channel activity	7/2342	43/18639	0.162790697674419	1.29558318272993	0.291949015371532	0.672904157415607
GO:0140767	enzyme-substrate adaptor activity	20/2342	139/18639	0.143884892086331	1.14511977096376	0.292750988685969	0.672904157415607
GO:0032931	histone H3K56 acetyltransferase activity	4/2342	22/18639	0.181818181818182	1.44701498330875	0.296086981994491	0.672904157415607
GO:0043992	histone H3K9 acetyltransferase activity	4/2342	22/18639	0.181818181818182	1.44701498330875	0.296086981994491	0.672904157415607
GO:0043993	histone H3K18 acetyltransferase activity	4/2342	22/18639	0.181818181818182	1.44701498330875	0.296086981994491	0.672904157415607
GO:0043994	histone H3K23 acetyltransferase activity	4/2342	22/18639	0.181818181818182	1.44701498330875	0.296086981994491	0.672904157415607
GO:0043999	histone H2AK5 acetyltransferase activity	4/2342	22/18639	0.181818181818182	1.44701498330875	0.296086981994491	0.672904157415607
GO:0044012	histone H2AK9 acetyltransferase activity	4/2342	22/18639	0.181818181818182	1.44701498330875	0.296086981994491	0.672904157415607
GO:0044014	histone H2BK5 acetyltransferase activity	4/2342	22/18639	0.181818181818182	1.44701498330875	0.296086981994491	0.672904157415607
GO:0044015	histone H2BK12 acetyltransferase activity	4/2342	22/18639	0.181818181818182	1.44701498330875	0.296086981994491	0.672904157415607
GO:0044016	histone H3K4 acetyltransferase activity	4/2342	22/18639	0.181818181818182	1.44701498330875	0.296086981994491	0.672904157415607
GO:0044017	histone H3K27 acetyltransferase activity	4/2342	22/18639	0.181818181818182	1.44701498330875	0.296086981994491	0.672904157415607
GO:0044018	histone H3K36 acetyltransferase activity	4/2342	22/18639	0.181818181818182	1.44701498330875	0.296086981994491	0.672904157415607
GO:0046972	histone H4K16 acetyltransferase activity	4/2342	22/18639	0.181818181818182	1.44701498330875	0.296086981994491	0.672904157415607
GO:0140035	ubiquitin-like protein reader activity	4/2342	22/18639	0.181818181818182	1.44701498330875	0.296086981994491	0.672904157415607
GO:0140908	histone H3K122 acetyltransferase activity	4/2342	22/18639	0.181818181818182	1.44701498330875	0.296086981994491	0.672904157415607
GO:0038024	cargo receptor activity	10/2342	65/18639	0.153846153846154	1.22439729356894	0.296603925783255	0.672904157415607
GO:0160215	deacylase activity	10/2342	65/18639	0.153846153846154	1.22439729356894	0.296603925783255	0.672904157415607
GO:0099604	ligand-gated calcium channel activity	5/2342	29/18639	0.172413793103448	1.37216938072381	0.29682377382536	0.672904157415607
GO:0106222	lncRNA binding	5/2342	29/18639	0.172413793103448	1.37216938072381	0.29682377382536	0.672904157415607
GO:0043539	protein serine/threonine kinase activator activity	11/2342	73/18639	0.150684931506849	1.19923844507095	0.307290519931214	0.692311551794668
GO:0005272	sodium channel activity	8/2342	51/18639	0.156862745098039	1.24840508363892	0.307516370581619	0.692311551794668
GO:0016830	carbon-carbon lyase activity	8/2342	51/18639	0.156862745098039	1.24840508363892	0.307516370581619	0.692311551794668
GO:0030544	Hsp70 protein binding	8/2342	51/18639	0.156862745098039	1.24840508363892	0.307516370581619	0.692311551794668
GO:0019213	deacetylase activity	6/2342	37/18639	0.162162162162162	1.29058093105915	0.318134246317108	0.711805153563089
GO:0030551	cyclic nucleotide binding	6/2342	37/18639	0.162162162162162	1.29058093105915	0.318134246317108	0.711805153563089
GO:0031593	polyubiquitin modification-dependent protein binding	9/2342	59/18639	0.152542372881356	1.21402104531836	0.320233280022941	0.711805153563089
GO:0008509	monoatomic anion transmembrane transporter activity	21/2342	149/18639	0.140939597315436	1.12167939981316	0.320763243549173	0.711805153563089
GO:0008187	poly-pyrimidine tract binding	5/2342	30/18639	0.166666666666667	1.32643040136635	0.322760582273642	0.711805153563089
GO:0098918	structural constituent of synapse	5/2342	30/18639	0.166666666666667	1.32643040136635	0.322760582273642	0.711805153563089
GO:0004707	MAP kinase activity	3/2342	16/18639	0.1875	1.49223420153715	0.325917644513046	0.711805153563089
GO:0004708	MAP kinase kinase activity	3/2342	16/18639	0.1875	1.49223420153715	0.325917644513046	0.711805153563089
GO:0005521	lamin binding	3/2342	16/18639	0.1875	1.49223420153715	0.325917644513046	0.711805153563089
GO:0008296	3'-5'-DNA exonuclease activity	3/2342	16/18639	0.1875	1.49223420153715	0.325917644513046	0.711805153563089
GO:0015562	efflux transmembrane transporter activity	3/2342	16/18639	0.1875	1.49223420153715	0.325917644513046	0.711805153563089
GO:0019841	retinol binding	3/2342	16/18639	0.1875	1.49223420153715	0.325917644513046	0.711805153563089
GO:0022858	alanine transmembrane transporter activity	3/2342	16/18639	0.1875	1.49223420153715	0.325917644513046	0.711805153563089
GO:0005212	structural constituent of eye lens	4/2342	23/18639	0.173913043478261	1.38410128838228	0.326038542240214	0.711805153563089
GO:0016493	C-C chemokine receptor activity	4/2342	23/18639	0.173913043478261	1.38410128838228	0.326038542240214	0.711805153563089
GO:0017134	fibroblast growth factor binding	4/2342	23/18639	0.173913043478261	1.38410128838228	0.326038542240214	0.711805153563089
GO:0044013	histone H2B acetyltransferase activity	4/2342	23/18639	0.173913043478261	1.38410128838228	0.326038542240214	0.711805153563089
GO:0099186	structural constituent of postsynapse	4/2342	23/18639	0.173913043478261	1.38410128838228	0.326038542240214	0.711805153563089
GO:0016755	aminoacyltransferase activity	66/2342	496/18639	0.133064516129032	1.05900491721991	0.326602397310673	0.711839788769404
GO:0005125	cytokine activity	32/2342	234/18639	0.136752136752137	1.08835314983906	0.331359954214842	0.720999297361943
GO:0008009	chemokine activity	7/2342	45/18639	0.155555555555556	1.23800170794193	0.334187626078183	0.725590280591105
GO:0015297	antiporter activity	19/2342	135/18639	0.140740740740741	1.12009678337603	0.334587050095513	0.725590280591105
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	18/2342	128/18639	0.140625	1.11917565115286	0.341976472839063	0.739209111718886
GO:0000149	SNARE binding	15/2342	106/18639	0.141509433962264	1.12621449172615	0.352441764880975	0.739209111718886
GO:0017171	serine hydrolase activity	27/2342	198/18639	0.136363636363636	1.08526123748156	0.354795504444549	0.739209111718886
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	7/2342	46/18639	0.152173913043478	1.2110886273345	0.355628223747015	0.739209111718886
GO:0004622	lysophospholipase activity	4/2342	24/18639	0.166666666666667	1.32643040136635	0.356156946963671	0.739209111718886
GO:0015149	hexose transmembrane transporter activity	4/2342	24/18639	0.166666666666667	1.32643040136635	0.356156946963671	0.739209111718886
GO:0035035	histone acetyltransferase binding	4/2342	24/18639	0.166666666666667	1.32643040136635	0.356156946963671	0.739209111718886
GO:0043998	histone H2A acetyltransferase activity	4/2342	24/18639	0.166666666666667	1.32643040136635	0.356156946963671	0.739209111718886
GO:0055056	D-glucose transmembrane transporter activity	4/2342	24/18639	0.166666666666667	1.32643040136635	0.356156946963671	0.739209111718886
GO:0008569	minus-end-directed microtubule motor activity	3/2342	17/18639	0.176470588235294	1.40445571909379	0.362263295886156	0.739209111718886
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	3/2342	17/18639	0.176470588235294	1.40445571909379	0.362263295886156	0.739209111718886
GO:0009881	photoreceptor activity	3/2342	17/18639	0.176470588235294	1.40445571909379	0.362263295886156	0.739209111718886
GO:0015347	sodium-independent organic anion transmembrane transporter activity	3/2342	17/18639	0.176470588235294	1.40445571909379	0.362263295886156	0.739209111718886
GO:0016805	dipeptidase activity	3/2342	17/18639	0.176470588235294	1.40445571909379	0.362263295886156	0.739209111718886
GO:0017110	nucleoside diphosphate phosphatase activity	3/2342	17/18639	0.176470588235294	1.40445571909379	0.362263295886156	0.739209111718886
GO:0030169	low-density lipoprotein particle binding	3/2342	17/18639	0.176470588235294	1.40445571909379	0.362263295886156	0.739209111718886
GO:0036041	long-chain fatty acid binding	3/2342	17/18639	0.176470588235294	1.40445571909379	0.362263295886156	0.739209111718886
GO:0038191	neuropilin binding	3/2342	17/18639	0.176470588235294	1.40445571909379	0.362263295886156	0.739209111718886
GO:0048038	quinone binding	3/2342	17/18639	0.176470588235294	1.40445571909379	0.362263295886156	0.739209111718886
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	17/2342	122/18639	0.139344262295082	1.10898279458498	0.362837415688303	0.739209111718886
GO:0000182	rDNA binding	2/2342	10/18639	0.2	1.59171648163962	0.363629424471415	0.739209111718886
GO:0001094	TFIID-class transcription factor complex binding	2/2342	10/18639	0.2	1.59171648163962	0.363629424471415	0.739209111718886
GO:0004445	inositol-polyphosphate 5-phosphatase activity	2/2342	10/18639	0.2	1.59171648163962	0.363629424471415	0.739209111718886
GO:0005522	profilin binding	2/2342	10/18639	0.2	1.59171648163962	0.363629424471415	0.739209111718886
GO:0005528	FK506 binding	2/2342	10/18639	0.2	1.59171648163962	0.363629424471415	0.739209111718886
GO:0008140	cAMP response element binding protein binding	2/2342	10/18639	0.2	1.59171648163962	0.363629424471415	0.739209111718886
GO:0015279	store-operated calcium channel activity	2/2342	10/18639	0.2	1.59171648163962	0.363629424471415	0.739209111718886
GO:0015658	branched-chain amino acid transmembrane transporter activity	2/2342	10/18639	0.2	1.59171648163962	0.363629424471415	0.739209111718886
GO:0016175	superoxide-generating NAD(P)H oxidase activity	2/2342	10/18639	0.2	1.59171648163962	0.363629424471415	0.739209111718886
GO:0016303	1-phosphatidylinositol-3-kinase activity	2/2342	10/18639	0.2	1.59171648163962	0.363629424471415	0.739209111718886
GO:0019531	oxalate transmembrane transporter activity	2/2342	10/18639	0.2	1.59171648163962	0.363629424471415	0.739209111718886
GO:0031996	thioesterase binding	2/2342	10/18639	0.2	1.59171648163962	0.363629424471415	0.739209111718886
GO:0036435	K48-linked polyubiquitin modification-dependent protein binding	2/2342	10/18639	0.2	1.59171648163962	0.363629424471415	0.739209111718886
GO:0042975	peroxisome proliferator activated receptor binding	2/2342	10/18639	0.2	1.59171648163962	0.363629424471415	0.739209111718886
GO:0043422	protein kinase B binding	2/2342	10/18639	0.2	1.59171648163962	0.363629424471415	0.739209111718886
GO:0051378	serotonin binding	2/2342	10/18639	0.2	1.59171648163962	0.363629424471415	0.739209111718886
GO:0051864	histone H3K36 demethylase activity	2/2342	10/18639	0.2	1.59171648163962	0.363629424471415	0.739209111718886
GO:0070097	delta-catenin binding	2/2342	10/18639	0.2	1.59171648163962	0.363629424471415	0.739209111718886
GO:0140135	mechanosensitive monoatomic cation channel activity	2/2342	10/18639	0.2	1.59171648163962	0.363629424471415	0.739209111718886
GO:1905394	retromer complex binding	2/2342	10/18639	0.2	1.59171648163962	0.363629424471415	0.739209111718886
GO:0051287	NAD binding	8/2342	54/18639	0.148148148148148	1.17904924565898	0.36678013794564	0.744449061236542
GO:0019787	ubiquitin-like protein transferase activity	63/2342	479/18639	0.131524008350731	1.04674465911583	0.367755382167972	0.745264027201553
GO:0008514	organic anion transmembrane transporter activity	36/2342	269/18639	0.133828996282528	1.06508909552094	0.368775164407458	0.746166570973969
GO:0016887	ATP hydrolysis activity	55/2342	417/18639	0.13189448441247	1.04969312338345	0.370583098022058	0.748658544837718
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	5/2342	32/18639	0.15625	1.24352850128096	0.375201395693129	0.753515687582363
GO:0051059	NF-kappaB binding	5/2342	32/18639	0.15625	1.24352850128096	0.375201395693129	0.753515687582363
GO:0070717	poly-purine tract binding	5/2342	32/18639	0.15625	1.24352850128096	0.375201395693129	0.753515687582363
GO:0016829	lyase activity	27/2342	200/18639	0.135	1.07440862510675	0.375388245009198	0.753515687582363
GO:0015179	L-amino acid transmembrane transporter activity	9/2342	62/18639	0.145161290322581	1.15527809151263	0.375887733297438	0.753515687582363
GO:0005504	fatty acid binding	7/2342	47/18639	0.148936170212766	1.18532078419972	0.377188403515469	0.753796517179375
GO:0140938	histone H3 methyltransferase activity	7/2342	47/18639	0.148936170212766	1.18532078419972	0.377188403515469	0.753796517179375
GO:0019211	phosphatase activator activity	4/2342	25/18639	0.16	1.2733731853117	0.386254780427233	0.766441478599138
GO:0047617	fatty acyl-CoA hydrolase activity	4/2342	25/18639	0.16	1.2733731853117	0.386254780427233	0.766441478599138
GO:0015144	carbohydrate transmembrane transporter activity	6/2342	40/18639	0.15	1.19378736122972	0.388639654818711	0.766441478599138
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	6/2342	40/18639	0.15	1.19378736122972	0.388639654818711	0.766441478599138
GO:0032451	demethylase activity	6/2342	40/18639	0.15	1.19378736122972	0.388639654818711	0.766441478599138
GO:0061791	GTPase motor activity	6/2342	40/18639	0.15	1.19378736122972	0.388639654818711	0.766441478599138
GO:0140662	ATP-dependent protein folding chaperone	6/2342	40/18639	0.15	1.19378736122972	0.388639654818711	0.766441478599138
GO:1990606	membrane scission GTPase motor activity	6/2342	40/18639	0.15	1.19378736122972	0.388639654818711	0.766441478599138
GO:0022836	gated channel activity	42/2342	318/18639	0.132075471698113	1.05113352561107	0.388825969512573	0.766441478599138
GO:0008236	serine-type peptidase activity	26/2342	194/18639	0.134020618556701	1.06661413718119	0.3937324935692	0.767887856594471
GO:1901682	sulfur compound transmembrane transporter activity	9/2342	63/18639	0.142857142857143	1.1369403440283	0.394647435221543	0.767887856594471
GO:0050660	flavin adenine dinucleotide binding	12/2342	86/18639	0.13953488372093	1.11049987091137	0.395697659538064	0.767887856594471
GO:0004970	glutamate-gated receptor activity	3/2342	18/18639	0.166666666666667	1.32643040136635	0.398281181907142	0.767887856594471
GO:0015172	acidic amino acid transmembrane transporter activity	3/2342	18/18639	0.166666666666667	1.32643040136635	0.398281181907142	0.767887856594471
GO:0015280	ligand-gated sodium channel activity	3/2342	18/18639	0.166666666666667	1.32643040136635	0.398281181907142	0.767887856594471
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	3/2342	18/18639	0.166666666666667	1.32643040136635	0.398281181907142	0.767887856594471
GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	3/2342	18/18639	0.166666666666667	1.32643040136635	0.398281181907142	0.767887856594471
GO:0034185	apolipoprotein binding	3/2342	18/18639	0.166666666666667	1.32643040136635	0.398281181907142	0.767887856594471
GO:0050811	GABA receptor binding	3/2342	18/18639	0.166666666666667	1.32643040136635	0.398281181907142	0.767887856594471
GO:0070628	proteasome binding	3/2342	18/18639	0.166666666666667	1.32643040136635	0.398281181907142	0.767887856594471
GO:1901611	phosphatidylglycerol binding	3/2342	18/18639	0.166666666666667	1.32643040136635	0.398281181907142	0.767887856594471
GO:0000099	sulfur amino acid transmembrane transporter activity	2/2342	11/18639	0.181818181818182	1.44701498330875	0.410795619134639	0.767887856594471
GO:0001851	complement component C3b binding	2/2342	11/18639	0.181818181818182	1.44701498330875	0.410795619134639	0.767887856594471
GO:0005114	type II transforming growth factor beta receptor binding	2/2342	11/18639	0.181818181818182	1.44701498330875	0.410795619134639	0.767887856594471
GO:0008172	S-methyltransferase activity	2/2342	11/18639	0.181818181818182	1.44701498330875	0.410795619134639	0.767887856594471
GO:0008199	ferric iron binding	2/2342	11/18639	0.181818181818182	1.44701498330875	0.410795619134639	0.767887856594471
GO:0008271	secondary active sulfate transmembrane transporter activity	2/2342	11/18639	0.181818181818182	1.44701498330875	0.410795619134639	0.767887856594471
GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity	2/2342	11/18639	0.181818181818182	1.44701498330875	0.410795619134639	0.767887856594471
GO:0015173	aromatic amino acid transmembrane transporter activity	2/2342	11/18639	0.181818181818182	1.44701498330875	0.410795619134639	0.767887856594471
GO:0016176	superoxide-generating NADPH oxidase activator activity	2/2342	11/18639	0.181818181818182	1.44701498330875	0.410795619134639	0.767887856594471
GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor	2/2342	11/18639	0.181818181818182	1.44701498330875	0.410795619134639	0.767887856594471
GO:0019107	myristoyltransferase activity	2/2342	11/18639	0.181818181818182	1.44701498330875	0.410795619134639	0.767887856594471
GO:0019203	carbohydrate phosphatase activity	2/2342	11/18639	0.181818181818182	1.44701498330875	0.410795619134639	0.767887856594471
GO:0019215	intermediate filament binding	2/2342	11/18639	0.181818181818182	1.44701498330875	0.410795619134639	0.767887856594471
GO:0032404	mismatch repair complex binding	2/2342	11/18639	0.181818181818182	1.44701498330875	0.410795619134639	0.767887856594471
GO:0035252	UDP-xylosyltransferase activity	2/2342	11/18639	0.181818181818182	1.44701498330875	0.410795619134639	0.767887856594471
GO:0042285	xylosyltransferase activity	2/2342	11/18639	0.181818181818182	1.44701498330875	0.410795619134639	0.767887856594471
GO:0045294	alpha-catenin binding	2/2342	11/18639	0.181818181818182	1.44701498330875	0.410795619134639	0.767887856594471
GO:0050786	RAGE receptor binding	2/2342	11/18639	0.181818181818182	1.44701498330875	0.410795619134639	0.767887856594471
GO:0070697	activin receptor binding	2/2342	11/18639	0.181818181818182	1.44701498330875	0.410795619134639	0.767887856594471
GO:0001727	lipid kinase activity	6/2342	41/18639	0.146341463414634	1.16467059632168	0.412226129648831	0.767887856594471
GO:0016877	ligase activity, forming carbon-sulfur bonds	6/2342	41/18639	0.146341463414634	1.16467059632168	0.412226129648831	0.767887856594471
GO:0001637	G protein-coupled chemoattractant receptor activity	4/2342	26/18639	0.153846153846154	1.22439729356894	0.416160932288305	0.767887856594471
GO:0004950	chemokine receptor activity	4/2342	26/18639	0.153846153846154	1.22439729356894	0.416160932288305	0.767887856594471
GO:0005227	calcium-activated cation channel activity	4/2342	26/18639	0.153846153846154	1.22439729356894	0.416160932288305	0.767887856594471
GO:0008066	glutamate receptor activity	4/2342	26/18639	0.153846153846154	1.22439729356894	0.416160932288305	0.767887856594471
GO:0008198	ferrous iron binding	4/2342	26/18639	0.153846153846154	1.22439729356894	0.416160932288305	0.767887856594471
GO:0015145	monosaccharide transmembrane transporter activity	4/2342	26/18639	0.153846153846154	1.22439729356894	0.416160932288305	0.767887856594471
GO:0016289	acyl-CoA hydrolase activity	4/2342	26/18639	0.153846153846154	1.22439729356894	0.416160932288305	0.767887856594471
GO:0019865	immunoglobulin binding	4/2342	26/18639	0.153846153846154	1.22439729356894	0.416160932288305	0.767887856594471
GO:0034237	protein kinase A regulatory subunit binding	4/2342	26/18639	0.153846153846154	1.22439729356894	0.416160932288305	0.767887856594471
GO:0050681	nuclear androgen receptor binding	4/2342	26/18639	0.153846153846154	1.22439729356894	0.416160932288305	0.767887856594471
GO:0050750	low-density lipoprotein particle receptor binding	4/2342	26/18639	0.153846153846154	1.22439729356894	0.416160932288305	0.767887856594471
GO:0051139	metal cation:proton antiporter activity	4/2342	26/18639	0.153846153846154	1.22439729356894	0.416160932288305	0.767887856594471
GO:0061630	ubiquitin protein ligase activity	46/2342	353/18639	0.130311614730878	1.03709572458106	0.419008860503171	0.771970671502176
GO:0140030	modification-dependent protein binding	23/2342	173/18639	0.132947976878613	1.05807742999166	0.419562197136672	0.771970671502176
GO:0019842	vitamin binding	20/2342	150/18639	0.133333333333333	1.06114432109308	0.424294285457913	0.779573234525925
GO:0030332	cyclin binding	5/2342	34/18639	0.147058823529412	1.17037976591149	0.427578467097843	0.782487896118107
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	30/2342	229/18639	0.131004366812227	1.04260904910892	0.432694223720808	0.782487896118107
GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)+] activity	3/2342	19/18639	0.157894736842105	1.25661827497865	0.433711535954609	0.782487896118107
GO:0005229	intracellularly calcium-gated chloride channel activity	3/2342	19/18639	0.157894736842105	1.25661827497865	0.433711535954609	0.782487896118107
GO:0005346	purine ribonucleotide transmembrane transporter activity	3/2342	19/18639	0.157894736842105	1.25661827497865	0.433711535954609	0.782487896118107
GO:0008381	mechanosensitive monoatomic ion channel activity	3/2342	19/18639	0.157894736842105	1.25661827497865	0.433711535954609	0.782487896118107
GO:0022821	solute:potassium antiporter activity	3/2342	19/18639	0.157894736842105	1.25661827497865	0.433711535954609	0.782487896118107
GO:0030506	ankyrin binding	3/2342	19/18639	0.157894736842105	1.25661827497865	0.433711535954609	0.782487896118107
GO:0042577	lipid phosphatase activity	3/2342	19/18639	0.157894736842105	1.25661827497865	0.433711535954609	0.782487896118107
GO:0042800	histone H3K4 methyltransferase activity	3/2342	19/18639	0.157894736842105	1.25661827497865	0.433711535954609	0.782487896118107
GO:0050145	nucleoside monophosphate kinase activity	3/2342	19/18639	0.157894736842105	1.25661827497865	0.433711535954609	0.782487896118107
GO:0140036	ubiquitin-modified protein reader activity	3/2342	19/18639	0.157894736842105	1.25661827497865	0.433711535954609	0.782487896118107
GO:0141147	intracellularly calcium-gated channel activity	3/2342	19/18639	0.157894736842105	1.25661827497865	0.433711535954609	0.782487896118107
GO:0035198	miRNA binding	6/2342	42/18639	0.142857142857143	1.1369403440283	0.435714457845986	0.783923934545617
GO:0051879	Hsp90 protein binding	6/2342	42/18639	0.142857142857143	1.1369403440283	0.435714457845986	0.783923934545617
GO:0005200	structural constituent of cytoskeleton	15/2342	112/18639	0.133928571428571	1.06588157252653	0.43764435367167	0.786307075269017
GO:0032182	ubiquitin-like protein binding	16/2342	120/18639	0.133333333333333	1.06114432109308	0.440291153106827	0.789969900394707
GO:0005044	scavenger receptor activity	4/2342	27/18639	0.148148148148148	1.17904924565898	0.445721356769587	0.794307246740829
GO:0008266	poly(U) RNA binding	4/2342	27/18639	0.148148148148148	1.17904924565898	0.445721356769587	0.794307246740829
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	4/2342	27/18639	0.148148148148148	1.17904924565898	0.445721356769587	0.794307246740829
GO:0005154	epidermal growth factor receptor binding	5/2342	35/18639	0.142857142857143	1.1369403440283	0.453465596638443	0.794307246740829
GO:0016229	steroid dehydrogenase activity	5/2342	35/18639	0.142857142857143	1.1369403440283	0.453465596638443	0.794307246740829
GO:0015108	chloride transmembrane transporter activity	16/2342	121/18639	0.132231404958678	1.05237453331545	0.454091144539046	0.794307246740829
GO:0000340	RNA 7-methylguanosine cap binding	2/2342	12/18639	0.166666666666667	1.32643040136635	0.456161051630992	0.794307246740829
GO:0004875	complement receptor activity	2/2342	12/18639	0.166666666666667	1.32643040136635	0.456161051630992	0.794307246740829
GO:0005095	GTPase inhibitor activity	2/2342	12/18639	0.166666666666667	1.32643040136635	0.456161051630992	0.794307246740829
GO:0008499	N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity	2/2342	12/18639	0.166666666666667	1.32643040136635	0.456161051630992	0.794307246740829
GO:0015132	prostaglandin transmembrane transporter activity	2/2342	12/18639	0.166666666666667	1.32643040136635	0.456161051630992	0.794307246740829
GO:0015269	calcium-activated potassium channel activity	2/2342	12/18639	0.166666666666667	1.32643040136635	0.456161051630992	0.794307246740829
GO:0016208	AMP binding	2/2342	12/18639	0.166666666666667	1.32643040136635	0.456161051630992	0.794307246740829
GO:0016840	carbon-nitrogen lyase activity	2/2342	12/18639	0.166666666666667	1.32643040136635	0.456161051630992	0.794307246740829
GO:0031543	peptidyl-proline dioxygenase activity	2/2342	12/18639	0.166666666666667	1.32643040136635	0.456161051630992	0.794307246740829
GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity	2/2342	12/18639	0.166666666666667	1.32643040136635	0.456161051630992	0.794307246740829
GO:0070410	co-SMAD binding	2/2342	12/18639	0.166666666666667	1.32643040136635	0.456161051630992	0.794307246740829
GO:0140829	bicarbonate:monoatomic anion antiporter activity	2/2342	12/18639	0.166666666666667	1.32643040136635	0.456161051630992	0.794307246740829
GO:0140900	chloride:bicarbonate antiporter activity	2/2342	12/18639	0.166666666666667	1.32643040136635	0.456161051630992	0.794307246740829
GO:1990247	N6-methyladenosine-containing RNA reader activity	2/2342	12/18639	0.166666666666667	1.32643040136635	0.456161051630992	0.794307246740829
GO:1990459	transferrin receptor binding	2/2342	12/18639	0.166666666666667	1.32643040136635	0.456161051630992	0.794307246740829
GO:1990817	poly(A) RNA polymerase activity	2/2342	12/18639	0.166666666666667	1.32643040136635	0.456161051630992	0.794307246740829
GO:0008170	N-methyltransferase activity	13/2342	98/18639	0.13265306122449	1.05573031945485	0.462243584927908	0.803821173790298
GO:0000339	RNA cap binding	3/2342	20/18639	0.15	1.19378736122972	0.468335881347576	0.805766546755138
GO:0001614	purinergic nucleotide receptor activity	3/2342	20/18639	0.15	1.19378736122972	0.468335881347576	0.805766546755138
GO:0004745	all-trans-retinol dehydrogenase (NAD+) activity	3/2342	20/18639	0.15	1.19378736122972	0.468335881347576	0.805766546755138
GO:0016408	C-acyltransferase activity	3/2342	20/18639	0.15	1.19378736122972	0.468335881347576	0.805766546755138
GO:0016502	nucleotide receptor activity	3/2342	20/18639	0.15	1.19378736122972	0.468335881347576	0.805766546755138
GO:0016505	peptidase activator activity involved in apoptotic process	3/2342	20/18639	0.15	1.19378736122972	0.468335881347576	0.805766546755138
GO:0031418	L-ascorbic acid binding	3/2342	20/18639	0.15	1.19378736122972	0.468335881347576	0.805766546755138
GO:0140664	ATP-dependent DNA damage sensor activity	3/2342	20/18639	0.15	1.19378736122972	0.468335881347576	0.805766546755138
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	9/2342	67/18639	0.134328358208955	1.06906330856393	0.469565262427744	0.805766546755138
GO:0042054	histone methyltransferase activity	9/2342	67/18639	0.134328358208955	1.06906330856393	0.469565262427744	0.805766546755138
GO:0036408	histone H3K14 acetyltransferase activity	4/2342	28/18639	0.142857142857143	1.1369403440283	0.474799351692725	0.810465647633179
GO:0051119	sugar transmembrane transporter activity	4/2342	28/18639	0.142857142857143	1.1369403440283	0.474799351692725	0.810465647633179
GO:0051959	dynein light intermediate chain binding	4/2342	28/18639	0.142857142857143	1.1369403440283	0.474799351692725	0.810465647633179
GO:0097718	disordered domain specific binding	4/2342	28/18639	0.142857142857143	1.1369403440283	0.474799351692725	0.810465647633179
GO:0016409	palmitoyltransferase activity	5/2342	36/18639	0.138888888888889	1.10535866780529	0.479021508596839	0.816599658356028
GO:0016790	thiolester hydrolase activity	6/2342	44/18639	0.136363636363636	1.08526123748156	0.482094707976172	0.819687206362627
GO:0019205	nucleobase-containing compound kinase activity	6/2342	44/18639	0.136363636363636	1.08526123748156	0.482094707976172	0.819687206362627
GO:0046982	protein heterodimerization activity	47/2342	369/18639	0.127371273712737	1.01369477827998	0.483865563497611	0.82162270193908
GO:0003777	microtubule motor activity	9/2342	68/18639	0.132352941176471	1.05334178932034	0.488062616007064	0.827667543333128
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	2/2342	13/18639	0.153846153846154	1.22439729356894	0.499433532871894	0.829513392414815
GO:0004993	G protein-coupled serotonin receptor activity	2/2342	13/18639	0.153846153846154	1.22439729356894	0.499433532871894	0.829513392414815
GO:0005035	death receptor activity	2/2342	13/18639	0.153846153846154	1.22439729356894	0.499433532871894	0.829513392414815
GO:0005338	nucleotide-sugar transmembrane transporter activity	2/2342	13/18639	0.153846153846154	1.22439729356894	0.499433532871894	0.829513392414815
GO:0008035	high-density lipoprotein particle binding	2/2342	13/18639	0.153846153846154	1.22439729356894	0.499433532871894	0.829513392414815
GO:0019855	calcium channel inhibitor activity	2/2342	13/18639	0.153846153846154	1.22439729356894	0.499433532871894	0.829513392414815
GO:0030955	potassium ion binding	2/2342	13/18639	0.153846153846154	1.22439729356894	0.499433532871894	0.829513392414815
GO:0039706	co-receptor binding	2/2342	13/18639	0.153846153846154	1.22439729356894	0.499433532871894	0.829513392414815
GO:0045028	G protein-coupled purinergic nucleotide receptor activity	2/2342	13/18639	0.153846153846154	1.22439729356894	0.499433532871894	0.829513392414815
GO:0046974	histone H3K9 methyltransferase activity	2/2342	13/18639	0.153846153846154	1.22439729356894	0.499433532871894	0.829513392414815
GO:0071714	icosanoid transmembrane transporter activity	2/2342	13/18639	0.153846153846154	1.22439729356894	0.499433532871894	0.829513392414815
GO:0071837	HMG box domain binding	2/2342	13/18639	0.153846153846154	1.22439729356894	0.499433532871894	0.829513392414815
GO:0089720	caspase binding	2/2342	13/18639	0.153846153846154	1.22439729356894	0.499433532871894	0.829513392414815
GO:0140410	monoatomic cation:bicarbonate symporter activity	2/2342	13/18639	0.153846153846154	1.22439729356894	0.499433532871894	0.829513392414815
GO:1901338	catecholamine binding	2/2342	13/18639	0.153846153846154	1.22439729356894	0.499433532871894	0.829513392414815
GO:0001846	opsonin binding	3/2342	21/18639	0.142857142857143	1.1369403440283	0.501974419220925	0.829513392414815
GO:0019200	carbohydrate kinase activity	3/2342	21/18639	0.142857142857143	1.1369403440283	0.501974419220925	0.829513392414815
GO:0072542	protein phosphatase activator activity	3/2342	21/18639	0.142857142857143	1.1369403440283	0.501974419220925	0.829513392414815
GO:0003785	actin monomer binding	4/2342	29/18639	0.137931034482759	1.09773550457905	0.503275444151503	0.829513392414815
GO:0004181	metallocarboxypeptidase activity	4/2342	29/18639	0.137931034482759	1.09773550457905	0.503275444151503	0.829513392414815
GO:0010484	histone H3 acetyltransferase activity	4/2342	29/18639	0.137931034482759	1.09773550457905	0.503275444151503	0.829513392414815
GO:0051539	4 iron, 4 sulfur cluster binding	6/2342	45/18639	0.133333333333333	1.06114432109308	0.504849643652786	0.829513392414815
GO:0005246	calcium channel regulator activity	7/2342	53/18639	0.132075471698113	1.05113352561107	0.505428222018925	0.829513392414815
GO:0008146	sulfotransferase activity	7/2342	53/18639	0.132075471698113	1.05113352561107	0.505428222018925	0.829513392414815
GO:0019905	syntaxin binding	8/2342	61/18639	0.131147540983607	1.04374851255057	0.505935450512672	0.829513392414815
GO:0008080	N-acetyltransferase activity	9/2342	69/18639	0.130434782608696	1.03807596628671	0.506392702220899	0.829513392414815
GO:0016279	protein-lysine N-methyltransferase activity	9/2342	69/18639	0.130434782608696	1.03807596628671	0.506392702220899	0.829513392414815
GO:0015103	inorganic anion transmembrane transporter activity	21/2342	165/18639	0.127272727272727	1.01291048831612	0.510259784013547	0.834795288959191
GO:0043177	organic acid binding	24/2342	189/18639	0.126984126984127	1.01061363913627	0.51100493964797	0.834962788179513
GO:0015171	amino acid transmembrane transporter activity	13/2342	102/18639	0.127450980392157	1.01432913045662	0.522937446986038	0.850734113479232
GO:0016278	lysine N-methyltransferase activity	9/2342	70/18639	0.128571428571429	1.02324630962547	0.524521860902652	0.850734113479232
GO:0140463	chromatin-protein adaptor activity	7/2342	54/18639	0.12962962962963	1.03166808995161	0.526077936668137	0.850734113479232
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	6/2342	46/18639	0.130434782608696	1.03807596628671	0.527232856638651	0.850734113479232
GO:0015215	nucleotide transmembrane transporter activity	4/2342	30/18639	0.133333333333333	1.06114432109308	0.531046961363481	0.850734113479232
GO:0031210	phosphatidylcholine binding	4/2342	30/18639	0.133333333333333	1.06114432109308	0.531046961363481	0.850734113479232
GO:0043995	histone H4K5 acetyltransferase activity	4/2342	30/18639	0.133333333333333	1.06114432109308	0.531046961363481	0.850734113479232
GO:0043996	histone H4K8 acetyltransferase activity	4/2342	30/18639	0.133333333333333	1.06114432109308	0.531046961363481	0.850734113479232
GO:0043997	histone H4K12 acetyltransferase activity	4/2342	30/18639	0.133333333333333	1.06114432109308	0.531046961363481	0.850734113479232
GO:0048019	receptor antagonist activity	4/2342	30/18639	0.133333333333333	1.06114432109308	0.531046961363481	0.850734113479232
GO:0070566	adenylyltransferase activity	4/2342	30/18639	0.133333333333333	1.06114432109308	0.531046961363481	0.850734113479232
GO:0004407	histone deacetylase activity	3/2342	22/18639	0.136363636363636	1.08526123748156	0.534482961940888	0.850734113479232
GO:0008970	phospholipase A1 activity	3/2342	22/18639	0.136363636363636	1.08526123748156	0.534482961940888	0.850734113479232
GO:0016881	acid-amino acid ligase activity	3/2342	22/18639	0.136363636363636	1.08526123748156	0.534482961940888	0.850734113479232
GO:0031683	G-protein beta/gamma-subunit complex binding	3/2342	22/18639	0.136363636363636	1.08526123748156	0.534482961940888	0.850734113479232
GO:0033558	protein lysine deacetylase activity	3/2342	22/18639	0.136363636363636	1.08526123748156	0.534482961940888	0.850734113479232
GO:0061133	endopeptidase activator activity	3/2342	22/18639	0.136363636363636	1.08526123748156	0.534482961940888	0.850734113479232
GO:0005347	ATP transmembrane transporter activity	2/2342	14/18639	0.142857142857143	1.1369403440283	0.540422666266796	0.850734113479232
GO:0008174	mRNA methyltransferase activity	2/2342	14/18639	0.142857142857143	1.1369403440283	0.540422666266796	0.850734113479232
GO:0008195	phosphatidate phosphatase activity	2/2342	14/18639	0.142857142857143	1.1369403440283	0.540422666266796	0.850734113479232
GO:0008392	arachidonate epoxygenase activity	2/2342	14/18639	0.142857142857143	1.1369403440283	0.540422666266796	0.850734113479232
GO:0008494	translation activator activity	2/2342	14/18639	0.142857142857143	1.1369403440283	0.540422666266796	0.850734113479232
GO:0015926	glucosidase activity	2/2342	14/18639	0.142857142857143	1.1369403440283	0.540422666266796	0.850734113479232
GO:0030283	testosterone dehydrogenase [NAD(P)+] activity	2/2342	14/18639	0.142857142857143	1.1369403440283	0.540422666266796	0.850734113479232
GO:0031404	chloride ion binding	2/2342	14/18639	0.142857142857143	1.1369403440283	0.540422666266796	0.850734113479232
GO:0032036	myosin heavy chain binding	2/2342	14/18639	0.142857142857143	1.1369403440283	0.540422666266796	0.850734113479232
GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity	2/2342	14/18639	0.142857142857143	1.1369403440283	0.540422666266796	0.850734113479232
GO:0070742	C2H2 zinc finger domain binding	2/2342	14/18639	0.142857142857143	1.1369403440283	0.540422666266796	0.850734113479232
GO:0098847	sequence-specific single stranded DNA binding	2/2342	14/18639	0.142857142857143	1.1369403440283	0.540422666266796	0.850734113479232
GO:1901612	cardiolipin binding	2/2342	14/18639	0.142857142857143	1.1369403440283	0.540422666266796	0.850734113479232
GO:0033293	monocarboxylic acid binding	10/2342	79/18639	0.126582278481013	1.00741549470862	0.540959490172322	0.850734113479232
GO:0004252	serine-type endopeptidase activity	22/2342	176/18639	0.125	0.994822801024765	0.544841593618275	0.855803180302466
GO:0061749	forked DNA-dependent helicase activity	6/2342	47/18639	0.127659574468085	1.01598924359976	0.549190581485946	0.860553154825384
GO:1990518	single-stranded 3'-5' DNA helicase activity	6/2342	47/18639	0.127659574468085	1.01598924359976	0.549190581485946	0.860553154825384
GO:0000217	DNA secondary structure binding	5/2342	39/18639	0.128205128205128	1.02033107797412	0.552888366712048	0.86530360043247
GO:0016407	acetyltransferase activity	12/2342	96/18639	0.125	0.994822801024765	0.554022450490707	0.866035094088362
GO:0048306	calcium-dependent protein binding	10/2342	80/18639	0.125	0.994822801024765	0.557708765006789	0.867078392527794
GO:0005164	tumor necrosis factor receptor binding	4/2342	31/18639	0.129032258064516	1.02691385912234	0.558027356545986	0.867078392527794
GO:0005310	dicarboxylic acid transmembrane transporter activity	4/2342	31/18639	0.129032258064516	1.02691385912234	0.558027356545986	0.867078392527794
GO:0005452	solute:inorganic anion antiporter activity	4/2342	31/18639	0.129032258064516	1.02691385912234	0.558027356545986	0.867078392527794
GO:0047499	calcium-independent phospholipase A2 activity	4/2342	31/18639	0.129032258064516	1.02691385912234	0.558027356545986	0.867078392527794
GO:0042379	chemokine receptor binding	9/2342	72/18639	0.125	0.994822801024765	0.560053789125861	0.869187421833326
GO:0003697	single-stranded DNA binding	15/2342	121/18639	0.12396694214876	0.986601124983238	0.563704237815386	0.871547564359477
GO:0000295	adenine nucleotide transmembrane transporter activity	3/2342	23/18639	0.130434782608696	1.03807596628671	0.56574962489599	0.871547564359477
GO:0004022	alcohol dehydrogenase (NAD+) activity	3/2342	23/18639	0.130434782608696	1.03807596628671	0.56574962489599	0.871547564359477
GO:0004602	glutathione peroxidase activity	3/2342	23/18639	0.130434782608696	1.03807596628671	0.56574962489599	0.871547564359477
GO:0061659	ubiquitin-like protein ligase activity	46/2342	372/18639	0.123655913978495	0.984125781658908	0.570591062016502	0.871547564359477
GO:0009378	four-way junction helicase activity	6/2342	48/18639	0.125	0.994822801024765	0.570674994175644	0.871547564359477
GO:0036121	double-stranded DNA helicase activity	6/2342	48/18639	0.125	0.994822801024765	0.570674994175644	0.871547564359477
GO:0043138	3'-5' DNA helicase activity	6/2342	48/18639	0.125	0.994822801024765	0.570674994175644	0.871547564359477
GO:0140693	molecular condensate scaffold activity	6/2342	48/18639	0.125	0.994822801024765	0.570674994175644	0.871547564359477
GO:0005506	iron ion binding	19/2342	154/18639	0.123376623376623	0.98190302438808	0.570789458993224	0.871547564359477
GO:0015036	disulfide oxidoreductase activity	5/2342	40/18639	0.125	0.994822801024765	0.576352468411096	0.871547564359477
GO:0031406	carboxylic acid binding	23/2342	187/18639	0.122994652406417	0.978863076944154	0.577225646370608	0.871547564359477
GO:0004865	protein serine/threonine phosphatase inhibitor activity	2/2342	15/18639	0.133333333333333	1.06114432109308	0.579018897646057	0.871547564359477
GO:0008242	omega peptidase activity	2/2342	15/18639	0.133333333333333	1.06114432109308	0.579018897646057	0.871547564359477
GO:0015116	sulfate transmembrane transporter activity	2/2342	15/18639	0.133333333333333	1.06114432109308	0.579018897646057	0.871547564359477
GO:0015250	water channel activity	2/2342	15/18639	0.133333333333333	1.06114432109308	0.579018897646057	0.871547564359477
GO:0015556	C4-dicarboxylate transmembrane transporter activity	2/2342	15/18639	0.133333333333333	1.06114432109308	0.579018897646057	0.871547564359477
GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	2/2342	15/18639	0.133333333333333	1.06114432109308	0.579018897646057	0.871547564359477
GO:0016846	carbon-sulfur lyase activity	2/2342	15/18639	0.133333333333333	1.06114432109308	0.579018897646057	0.871547564359477
GO:0017081	chloride channel regulator activity	2/2342	15/18639	0.133333333333333	1.06114432109308	0.579018897646057	0.871547564359477
GO:0031005	filamin binding	2/2342	15/18639	0.133333333333333	1.06114432109308	0.579018897646057	0.871547564359477
GO:0034483	heparan sulfate sulfotransferase activity	2/2342	15/18639	0.133333333333333	1.06114432109308	0.579018897646057	0.871547564359477
GO:0045504	dynein heavy chain binding	2/2342	15/18639	0.133333333333333	1.06114432109308	0.579018897646057	0.871547564359477
GO:0048531	beta-1,3-galactosyltransferase activity	2/2342	15/18639	0.133333333333333	1.06114432109308	0.579018897646057	0.871547564359477
GO:0061578	K63-linked deubiquitinase activity	2/2342	15/18639	0.133333333333333	1.06114432109308	0.579018897646057	0.871547564359477
GO:0140161	monocarboxylate:sodium symporter activity	2/2342	15/18639	0.133333333333333	1.06114432109308	0.579018897646057	0.871547564359477
GO:0042626	ATPase-coupled transmembrane transporter activity	12/2342	98/18639	0.122448979591837	0.974520294881403	0.584065541114867	0.87520739433523
GO:0015106	bicarbonate transmembrane transporter activity	4/2342	32/18639	0.125	0.994822801024765	0.584145350953537	0.87520739433523
GO:0030515	snoRNA binding	4/2342	32/18639	0.125	0.994822801024765	0.584145350953537	0.87520739433523
GO:0047498	calcium-dependent phospholipase A2 activity	4/2342	32/18639	0.125	0.994822801024765	0.584145350953537	0.87520739433523
GO:0016763	pentosyltransferase activity	6/2342	49/18639	0.122448979591837	0.974520294881403	0.591644127973831	0.883336958221349
GO:0060590	ATPase regulator activity	6/2342	49/18639	0.122448979591837	0.974520294881403	0.591644127973831	0.883336958221349
GO:0035064	methylated histone binding	9/2342	74/18639	0.121621621621622	0.967935698294366	0.594434020562802	0.883336958221349
GO:0004806	triacylglycerol lipase activity	3/2342	24/18639	0.125	0.994822801024765	0.595691436029177	0.883336958221349
GO:0005315	phosphate transmembrane transporter activity	3/2342	24/18639	0.125	0.994822801024765	0.595691436029177	0.883336958221349
GO:0005540	hyaluronic acid binding	3/2342	24/18639	0.125	0.994822801024765	0.595691436029177	0.883336958221349
GO:0030215	semaphorin receptor binding	3/2342	24/18639	0.125	0.994822801024765	0.595691436029177	0.883336958221349
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	3/2342	24/18639	0.125	0.994822801024765	0.595691436029177	0.883336958221349
GO:0140612	DNA damage sensor activity	3/2342	24/18639	0.125	0.994822801024765	0.595691436029177	0.883336958221349
GO:0061980	regulatory RNA binding	7/2342	58/18639	0.120689655172414	0.96051856650667	0.604922961453854	0.89600333743279
GO:0015605	organophosphate ester transmembrane transporter activity	6/2342	50/18639	0.12	0.955029888983774	0.612061731202633	0.902953569671571
GO:0000062	fatty-acyl-CoA binding	2/2342	16/18639	0.125	0.994822801024765	0.615176219522202	0.902953569671571
GO:0004198	calcium-dependent cysteine-type endopeptidase activity	2/2342	16/18639	0.125	0.994822801024765	0.615176219522202	0.902953569671571
GO:0008391	arachidonate monooxygenase activity	2/2342	16/18639	0.125	0.994822801024765	0.615176219522202	0.902953569671571
GO:0015385	sodium:proton antiporter activity	2/2342	16/18639	0.125	0.994822801024765	0.615176219522202	0.902953569671571
GO:0097027	ubiquitin-protein transferase activator activity	2/2342	16/18639	0.125	0.994822801024765	0.615176219522202	0.902953569671571
GO:0099507	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	2/2342	16/18639	0.125	0.994822801024765	0.615176219522202	0.902953569671571
GO:0106018	phosphatidylinositol-3,5-bisphosphate phosphatase activity	2/2342	16/18639	0.125	0.994822801024765	0.615176219522202	0.902953569671571
GO:0052689	carboxylic ester hydrolase activity	11/2342	92/18639	0.119565217391304	0.951569635762819	0.617310125431243	0.905063039430231
GO:0019894	kinesin binding	5/2342	42/18639	0.119047619047619	0.947450286690252	0.621233379103135	0.909082985411874
GO:0001848	complement binding	3/2342	25/18639	0.12	0.955029888983774	0.624250979974897	0.909082985411874
GO:0008483	transaminase activity	3/2342	25/18639	0.12	0.955029888983774	0.624250979974897	0.909082985411874
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	3/2342	25/18639	0.12	0.955029888983774	0.624250979974897	0.909082985411874
GO:0019706	protein-cysteine S-palmitoyltransferase activity	3/2342	25/18639	0.12	0.955029888983774	0.624250979974897	0.909082985411874
GO:0019707	protein-cysteine S-acyltransferase activity	3/2342	25/18639	0.12	0.955029888983774	0.624250979974897	0.909082985411874
GO:0140034	methylation-dependent protein binding	9/2342	76/18639	0.118421052631579	0.942463706233988	0.627475221290671	0.91275510913391
GO:0015020	glucuronosyltransferase activity	4/2342	34/18639	0.117647058823529	0.936303812729191	0.633579341821059	0.917524598690698
GO:0015035	protein-disulfide reductase activity	4/2342	34/18639	0.117647058823529	0.936303812729191	0.633579341821059	0.917524598690698
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	4/2342	34/18639	0.117647058823529	0.936303812729191	0.633579341821059	0.917524598690698
GO:0016831	carboxy-lyase activity	4/2342	34/18639	0.117647058823529	0.936303812729191	0.633579341821059	0.917524598690698
GO:0001098	basal transcription machinery binding	7/2342	60/18639	0.116666666666667	0.928501280956448	0.641633922962541	0.924764715825358
GO:0001099	basal RNA polymerase II transcription machinery binding	7/2342	60/18639	0.116666666666667	0.928501280956448	0.641633922962541	0.924764715825358
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	7/2342	60/18639	0.116666666666667	0.928501280956448	0.641633922962541	0.924764715825358
GO:0004549	tRNA-specific ribonuclease activity	2/2342	17/18639	0.117647058823529	0.936303812729191	0.648897942673675	0.924764715825358
GO:0004550	nucleoside diphosphate kinase activity	2/2342	17/18639	0.117647058823529	0.936303812729191	0.648897942673675	0.924764715825358
GO:0005092	GDP-dissociation inhibitor activity	2/2342	17/18639	0.117647058823529	0.936303812729191	0.648897942673675	0.924764715825358
GO:0015278	intracellularly gated calcium channel activity	2/2342	17/18639	0.117647058823529	0.936303812729191	0.648897942673675	0.924764715825358
GO:0031489	myosin V binding	2/2342	17/18639	0.117647058823529	0.936303812729191	0.648897942673675	0.924764715825358
GO:0032183	SUMO binding	2/2342	17/18639	0.117647058823529	0.936303812729191	0.648897942673675	0.924764715825358
GO:0045125	bioactive lipid receptor activity	2/2342	17/18639	0.117647058823529	0.936303812729191	0.648897942673675	0.924764715825358
GO:0045236	CXCR chemokine receptor binding	2/2342	17/18639	0.117647058823529	0.936303812729191	0.648897942673675	0.924764715825358
GO:0051787	misfolded protein binding	2/2342	17/18639	0.117647058823529	0.936303812729191	0.648897942673675	0.924764715825358
GO:0070403	NAD+ binding	2/2342	17/18639	0.117647058823529	0.936303812729191	0.648897942673675	0.924764715825358
GO:1901567	fatty acid derivative binding	2/2342	17/18639	0.117647058823529	0.936303812729191	0.648897942673675	0.924764715825358
GO:0004529	DNA exonuclease activity	3/2342	26/18639	0.115384615384615	0.918297970176706	0.651393160107931	0.924764715825358
GO:0008157	protein phosphatase 1 binding	3/2342	26/18639	0.115384615384615	0.918297970176706	0.651393160107931	0.924764715825358
GO:0015216	purine nucleotide transmembrane transporter activity	3/2342	26/18639	0.115384615384615	0.918297970176706	0.651393160107931	0.924764715825358
GO:0097602	cullin family protein binding	3/2342	26/18639	0.115384615384615	0.918297970176706	0.651393160107931	0.924764715825358
GO:0004623	phospholipase A2 activity	4/2342	35/18639	0.114285714285714	0.909552275222642	0.656819825070429	0.929421517174823
GO:0010485	histone H4 acetyltransferase activity	4/2342	35/18639	0.114285714285714	0.909552275222642	0.656819825070429	0.929421517174823
GO:0043015	gamma-tubulin binding	4/2342	35/18639	0.114285714285714	0.909552275222642	0.656819825070429	0.929421517174823
GO:0016836	hydro-lyase activity	7/2342	61/18639	0.114754098360656	0.913279948481752	0.659224465687523	0.931809119617076
GO:0030547	signaling receptor inhibitor activity	5/2342	44/18639	0.113636363636364	0.904384364567968	0.663150775116365	0.936340061821911
GO:0008028	monocarboxylic acid transmembrane transporter activity	8/2342	70/18639	0.114285714285714	0.909552275222642	0.666906189516035	0.940620130490043
GO:0034212	protein N-acetyltransferase activity	6/2342	53/18639	0.113207547169811	0.900971593380919	0.669724282151743	0.943149065896532
GO:0051082	unfolded protein binding	14/2342	121/18639	0.115702479338843	0.920827716651022	0.670575419602963	0.943149065896532
GO:0015291	secondary active transmembrane transporter activity	34/2342	287/18639	0.118466898954704	0.94282857797469	0.670877395603076	0.943149065896532
GO:0046943	carboxylic acid transmembrane transporter activity	22/2342	188/18639	0.117021276595745	0.93132347329978	0.672841093167238	0.94376276925272
GO:0005385	zinc ion transmembrane transporter activity	3/2342	27/18639	0.111111111111111	0.884286934244236	0.677102135525224	0.94376276925272
GO:0008320	protein transmembrane transporter activity	3/2342	27/18639	0.111111111111111	0.884286934244236	0.677102135525224	0.94376276925272
GO:0008395	steroid hydroxylase activity	3/2342	27/18639	0.111111111111111	0.884286934244236	0.677102135525224	0.94376276925272
GO:0005484	SNAP receptor activity	4/2342	36/18639	0.111111111111111	0.884286934244236	0.679044614629628	0.94376276925272
GO:0045505	dynein intermediate chain binding	4/2342	36/18639	0.111111111111111	0.884286934244236	0.679044614629628	0.94376276925272
GO:0055106	ubiquitin-protein transferase regulator activity	4/2342	36/18639	0.111111111111111	0.884286934244236	0.679044614629628	0.94376276925272
GO:0005372	water transmembrane transporter activity	2/2342	18/18639	0.111111111111111	0.884286934244236	0.680225037769491	0.94376276925272
GO:0008308	voltage-gated monoatomic anion channel activity	2/2342	18/18639	0.111111111111111	0.884286934244236	0.680225037769491	0.94376276925272
GO:0017075	syntaxin-1 binding	2/2342	18/18639	0.111111111111111	0.884286934244236	0.680225037769491	0.94376276925272
GO:0099602	neurotransmitter receptor regulator activity	2/2342	18/18639	0.111111111111111	0.884286934244236	0.680225037769491	0.94376276925272
GO:1990381	ubiquitin-specific protease binding	2/2342	18/18639	0.111111111111111	0.884286934244236	0.680225037769491	0.94376276925272
GO:0005342	organic acid transmembrane transporter activity	22/2342	189/18639	0.116402116402116	0.926395835874914	0.682612515557468	0.94376276925272
GO:0008528	G protein-coupled peptide receptor activity	14/2342	122/18639	0.114754098360656	0.913279948481752	0.682687469772354	0.94376276925272
GO:0140299	molecular sensor activity	8/2342	71/18639	0.112676056338028	0.896741679796971	0.682714134144953	0.94376276925272
GO:0046915	transition metal ion transmembrane transporter activity	5/2342	45/18639	0.111111111111111	0.884286934244236	0.682938416549313	0.94376276925272
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	21/2342	181/18639	0.116022099447514	0.923371439625196	0.68593409535116	0.946895207078807
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	6/2342	54/18639	0.111111111111111	0.884286934244236	0.687680075337194	0.948297683506386
GO:0005507	copper ion binding	7/2342	63/18639	0.111111111111111	0.884286934244236	0.692793198142718	0.95433548715524
GO:0004497	monooxygenase activity	12/2342	106/18639	0.113207547169811	0.900971593380919	0.694164955577011	0.955212158150993
GO:0003727	single-stranded RNA binding	10/2342	89/18639	0.112359550561798	0.894222742494171	0.695045153451134	0.955411274426479
GO:0005242	inward rectifier potassium channel activity	3/2342	28/18639	0.107142857142857	0.852705258021227	0.701378469585124	0.962080920793111
GO:0046966	nuclear thyroid hormone receptor binding	3/2342	28/18639	0.107142857142857	0.852705258021227	0.701378469585124	0.962080920793111
GO:0003756	protein disulfide isomerase activity	2/2342	19/18639	0.105263157894737	0.837745516652434	0.709226626218301	0.963769758429855
GO:0008574	plus-end-directed microtubule motor activity	2/2342	19/18639	0.105263157894737	0.837745516652434	0.709226626218301	0.963769758429855
GO:0015355	secondary active monocarboxylate transmembrane transporter activity	2/2342	19/18639	0.105263157894737	0.837745516652434	0.709226626218301	0.963769758429855
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	2/2342	19/18639	0.105263157894737	0.837745516652434	0.709226626218301	0.963769758429855
GO:0099589	serotonin receptor activity	2/2342	19/18639	0.105263157894737	0.837745516652434	0.709226626218301	0.963769758429855
GO:0120227	acyl-CoA binding	2/2342	19/18639	0.105263157894737	0.837745516652434	0.709226626218301	0.963769758429855
GO:0061733	protein-lysine-acetyltransferase activity	5/2342	47/18639	0.106382978723404	0.8466577029998	0.720109794462783	0.963769758429855
GO:0005109	frizzled binding	4/2342	38/18639	0.105263157894737	0.837745516652434	0.720411893351958	0.963769758429855
GO:0016417	S-acyltransferase activity	3/2342	29/18639	0.103448275862069	0.823301628434288	0.724236510981311	0.963769758429855
GO:0035250	UDP-galactosyltransferase activity	3/2342	29/18639	0.103448275862069	0.823301628434288	0.724236510981311	0.963769758429855
GO:0048029	monosaccharide binding	8/2342	74/18639	0.108108108108108	0.86038728737277	0.727254404469718	0.963769758429855
GO:0043024	ribosomal small subunit binding	2/2342	20/18639	0.1	0.795858240819812	0.735992264537271	0.963769758429855
GO:0061608	nuclear import signal receptor activity	2/2342	20/18639	0.1	0.795858240819812	0.735992264537271	0.963769758429855
GO:0015932	nucleobase-containing compound transmembrane transporter activity	6/2342	57/18639	0.105263157894737	0.837745516652434	0.737592906514559	0.963769758429855
GO:0003680	minor groove of adenine-thymine-rich DNA binding	1/2342	10/18639	0.1	0.795858240819812	0.738964341336517	0.963769758429855
GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	1/2342	10/18639	0.1	0.795858240819812	0.738964341336517	0.963769758429855
GO:0004935	adrenergic receptor activity	1/2342	10/18639	0.1	0.795858240819812	0.738964341336517	0.963769758429855
GO:0004983	neuropeptide Y receptor activity	1/2342	10/18639	0.1	0.795858240819812	0.738964341336517	0.963769758429855
GO:0005031	tumor necrosis factor receptor activity	1/2342	10/18639	0.1	0.795858240819812	0.738964341336517	0.963769758429855
GO:0005381	iron ion transmembrane transporter activity	1/2342	10/18639	0.1	0.795858240819812	0.738964341336517	0.963769758429855
GO:0008190	eukaryotic initiation factor 4E binding	1/2342	10/18639	0.1	0.795858240819812	0.738964341336517	0.963769758429855
GO:0008239	dipeptidyl-peptidase activity	1/2342	10/18639	0.1	0.795858240819812	0.738964341336517	0.963769758429855
GO:0008297	single-stranded DNA exodeoxyribonuclease activity	1/2342	10/18639	0.1	0.795858240819812	0.738964341336517	0.963769758429855
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	1/2342	10/18639	0.1	0.795858240819812	0.738964341336517	0.963769758429855
GO:0008401	retinoic acid 4-hydroxylase activity	1/2342	10/18639	0.1	0.795858240819812	0.738964341336517	0.963769758429855
GO:0008519	ammonium channel activity	1/2342	10/18639	0.1	0.795858240819812	0.738964341336517	0.963769758429855
GO:0015187	glycine transmembrane transporter activity	1/2342	10/18639	0.1	0.795858240819812	0.738964341336517	0.963769758429855
GO:0015203	polyamine transmembrane transporter activity	1/2342	10/18639	0.1	0.795858240819812	0.738964341336517	0.963769758429855
GO:0015643	toxic substance binding	1/2342	10/18639	0.1	0.795858240819812	0.738964341336517	0.963769758429855
GO:0015924	mannosyl-oligosaccharide mannosidase activity	1/2342	10/18639	0.1	0.795858240819812	0.738964341336517	0.963769758429855
GO:0016427	tRNA (cytidine) methyltransferase activity	1/2342	10/18639	0.1	0.795858240819812	0.738964341336517	0.963769758429855
GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines	1/2342	10/18639	0.1	0.795858240819812	0.738964341336517	0.963769758429855
GO:0016868	intramolecular phosphotransferase activity	1/2342	10/18639	0.1	0.795858240819812	0.738964341336517	0.963769758429855
GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor	1/2342	10/18639	0.1	0.795858240819812	0.738964341336517	0.963769758429855
GO:0016889	DNA endonuclease activity, producing 3'-phosphomonoesters	1/2342	10/18639	0.1	0.795858240819812	0.738964341336517	0.963769758429855
GO:0031957	very long-chain fatty acid-CoA ligase activity	1/2342	10/18639	0.1	0.795858240819812	0.738964341336517	0.963769758429855
GO:0032356	oxidized DNA binding	1/2342	10/18639	0.1	0.795858240819812	0.738964341336517	0.963769758429855
GO:0043225	ATPase-coupled inorganic anion transmembrane transporter activity	1/2342	10/18639	0.1	0.795858240819812	0.738964341336517	0.963769758429855
GO:0043295	glutathione binding	1/2342	10/18639	0.1	0.795858240819812	0.738964341336517	0.963769758429855
GO:0050308	sugar-phosphatase activity	1/2342	10/18639	0.1	0.795858240819812	0.738964341336517	0.963769758429855
GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding	1/2342	10/18639	0.1	0.795858240819812	0.738964341336517	0.963769758429855
GO:0050815	phosphoserine residue binding	1/2342	10/18639	0.1	0.795858240819812	0.738964341336517	0.963769758429855
GO:0051880	G-quadruplex DNA binding	1/2342	10/18639	0.1	0.795858240819812	0.738964341336517	0.963769758429855
GO:0072582	17-beta-hydroxysteroid dehydrogenase (NADP+) activity	1/2342	10/18639	0.1	0.795858240819812	0.738964341336517	0.963769758429855
GO:0098505	G-rich strand telomeric DNA binding	1/2342	10/18639	0.1	0.795858240819812	0.738964341336517	0.963769758429855
GO:0099122	RNA polymerase II C-terminal domain binding	1/2342	10/18639	0.1	0.795858240819812	0.738964341336517	0.963769758429855
GO:0140999	histone H3K4 trimethyltransferase activity	1/2342	10/18639	0.1	0.795858240819812	0.738964341336517	0.963769758429855
GO:0141109	transporter activator activity	1/2342	10/18639	0.1	0.795858240819812	0.738964341336517	0.963769758429855
GO:1990757	ubiquitin ligase activator activity	1/2342	10/18639	0.1	0.795858240819812	0.738964341336517	0.963769758429855
GO:0008168	methyltransferase activity	23/2342	204/18639	0.112745098039216	0.897291153865474	0.74237052878137	0.964912219836534
GO:0099094	ligand-gated monoatomic cation channel activity	15/2342	136/18639	0.110294117647059	0.877784824433616	0.743498445902788	0.964912219836534
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	3/2342	30/18639	0.1	0.795858240819812	0.745702016494403	0.964912219836534
GO:0016769	transferase activity, transferring nitrogenous groups	3/2342	30/18639	0.1	0.795858240819812	0.745702016494403	0.964912219836534
GO:0033612	receptor serine/threonine kinase binding	3/2342	30/18639	0.1	0.795858240819812	0.745702016494403	0.964912219836534
GO:0051213	dioxygenase activity	10/2342	93/18639	0.10752688172043	0.855761549268615	0.746722811396811	0.964912219836534
GO:0001653	peptide receptor activity	14/2342	128/18639	0.109375	0.87046995089667	0.74973093411239	0.964912219836534
GO:0008408	3'-5' exonuclease activity	6/2342	58/18639	0.103448275862069	0.823301628434288	0.752900977098487	0.964912219836534
GO:0017116	single-stranded DNA helicase activity	6/2342	58/18639	0.103448275862069	0.823301628434288	0.752900977098487	0.964912219836534
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	4/2342	40/18639	0.1	0.795858240819812	0.757691324902836	0.964912219836534
GO:0050997	quaternary ammonium group binding	4/2342	40/18639	0.1	0.795858240819812	0.757691324902836	0.964912219836534
GO:0071855	neuropeptide receptor binding	4/2342	40/18639	0.1	0.795858240819812	0.757691324902836	0.964912219836534
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	2/2342	21/18639	0.0952380952380952	0.757960229352202	0.760625721938991	0.964912219836534
GO:0015125	bile acid transmembrane transporter activity	2/2342	21/18639	0.0952380952380952	0.757960229352202	0.760625721938991	0.964912219836534
GO:0061891	calcium ion sensor activity	2/2342	21/18639	0.0952380952380952	0.757960229352202	0.760625721938991	0.964912219836534
GO:0070182	DNA polymerase binding	2/2342	21/18639	0.0952380952380952	0.757960229352202	0.760625721938991	0.964912219836534
GO:0016741	transferase activity, transferring one-carbon groups	24/2342	215/18639	0.111627906976744	0.888399896729093	0.762824376799432	0.964912219836534
GO:0140104	molecular carrier activity	28/2342	249/18639	0.112449799196787	0.894940993692961	0.763586357667787	0.964912219836534
GO:0015081	sodium ion transmembrane transporter activity	18/2342	164/18639	0.109756097560976	0.873502947241257	0.764743936832683	0.964912219836534
GO:0005184	neuropeptide hormone activity	3/2342	31/18639	0.0967741935483871	0.770185394341754	0.765810015774591	0.964912219836534
GO:0008327	methyl-CpG binding	3/2342	31/18639	0.0967741935483871	0.770185394341754	0.765810015774591	0.964912219836534
GO:0070063	RNA polymerase binding	6/2342	59/18639	0.101694915254237	0.809347363545572	0.767547118150345	0.964912219836534
GO:0016798	hydrolase activity, acting on glycosyl bonds	14/2342	130/18639	0.107692307692308	0.857078105498259	0.769848898309	0.964912219836534
GO:0008276	protein methyltransferase activity	10/2342	95/18639	0.105263157894737	0.837745516652434	0.770200587138386	0.964912219836534
GO:0000014	single-stranded DNA endodeoxyribonuclease activity	1/2342	11/18639	0.0909090909090909	0.723507491654375	0.771781213556704	0.964912219836534
GO:0004143	ATP-dependent diacylglycerol kinase activity	1/2342	11/18639	0.0909090909090909	0.723507491654375	0.771781213556704	0.964912219836534
GO:0005221	intracellularly cyclic nucleotide-activated monoatomic cation channel activity	1/2342	11/18639	0.0909090909090909	0.723507491654375	0.771781213556704	0.964912219836534
GO:0008046	axon guidance receptor activity	1/2342	11/18639	0.0909090909090909	0.723507491654375	0.771781213556704	0.964912219836534
GO:0008526	phosphatidylinositol transfer activity	1/2342	11/18639	0.0909090909090909	0.723507491654375	0.771781213556704	0.964912219836534
GO:0015217	ADP transmembrane transporter activity	1/2342	11/18639	0.0909090909090909	0.723507491654375	0.771781213556704	0.964912219836534
GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	1/2342	11/18639	0.0909090909090909	0.723507491654375	0.771781213556704	0.964912219836534
GO:0016725	oxidoreductase activity, acting on CH or CH2 groups	1/2342	11/18639	0.0909090909090909	0.723507491654375	0.771781213556704	0.964912219836534
GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives	1/2342	11/18639	0.0909090909090909	0.723507491654375	0.771781213556704	0.964912219836534
GO:0032050	clathrin heavy chain binding	1/2342	11/18639	0.0909090909090909	0.723507491654375	0.771781213556704	0.964912219836534
GO:0032794	GTPase activating protein binding	1/2342	11/18639	0.0909090909090909	0.723507491654375	0.771781213556704	0.964912219836534
GO:0034511	U3 snoRNA binding	1/2342	11/18639	0.0909090909090909	0.723507491654375	0.771781213556704	0.964912219836534
GO:0034594	phosphatidylinositol trisphosphate phosphatase activity	1/2342	11/18639	0.0909090909090909	0.723507491654375	0.771781213556704	0.964912219836534
GO:0043855	cyclic nucleotide-activated monoatomic ion channel activity	1/2342	11/18639	0.0909090909090909	0.723507491654375	0.771781213556704	0.964912219836534
GO:0047676	arachidonate-CoA ligase activity	1/2342	11/18639	0.0909090909090909	0.723507491654375	0.771781213556704	0.964912219836534
GO:0070990	snRNP binding	1/2342	11/18639	0.0909090909090909	0.723507491654375	0.771781213556704	0.964912219836534
GO:0099528	G protein-coupled neurotransmitter receptor activity	1/2342	11/18639	0.0909090909090909	0.723507491654375	0.771781213556704	0.964912219836534
GO:0140537	transcription regulator activator activity	1/2342	11/18639	0.0909090909090909	0.723507491654375	0.771781213556704	0.964912219836534
GO:1900750	oligopeptide binding	1/2342	11/18639	0.0909090909090909	0.723507491654375	0.771781213556704	0.964912219836534
GO:0001530	lipopolysaccharide binding	4/2342	41/18639	0.0975609756097561	0.776447064214451	0.774831166163771	0.965010244340114
GO:0008227	G protein-coupled amine receptor activity	4/2342	41/18639	0.0975609756097561	0.776447064214451	0.774831166163771	0.965010244340114
GO:0015175	neutral L-amino acid transmembrane transporter activity	4/2342	41/18639	0.0975609756097561	0.776447064214451	0.774831166163771	0.965010244340114
GO:0140318	protein transporter activity	4/2342	41/18639	0.0975609756097561	0.776447064214451	0.774831166163771	0.965010244340114
GO:0005243	gap junction channel activity	2/2342	22/18639	0.0909090909090909	0.723507491654375	0.783239997938801	0.9651898553357
GO:0070034	telomerase RNA binding	2/2342	22/18639	0.0909090909090909	0.723507491654375	0.783239997938801	0.9651898553357
GO:0140517	protein-RNA adaptor activity	2/2342	22/18639	0.0909090909090909	0.723507491654375	0.783239997938801	0.9651898553357
GO:0140784	metal ion sensor activity	2/2342	22/18639	0.0909090909090909	0.723507491654375	0.783239997938801	0.9651898553357
GO:0008378	galactosyltransferase activity	3/2342	32/18639	0.09375	0.746117100768574	0.78460291213539	0.9651898553357
GO:0022884	macromolecule transmembrane transporter activity	3/2342	32/18639	0.09375	0.746117100768574	0.78460291213539	0.9651898553357
GO:0043425	bHLH transcription factor binding	3/2342	32/18639	0.09375	0.746117100768574	0.78460291213539	0.9651898553357
GO:0160041	neuropeptide activity	3/2342	32/18639	0.09375	0.746117100768574	0.78460291213539	0.9651898553357
GO:0005179	hormone activity	14/2342	132/18639	0.106060606060606	0.844092073596771	0.788831348624824	0.9651898553357
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	18/2342	167/18639	0.107784431137725	0.857811277530336	0.790325791155089	0.9651898553357
GO:0016874	ligase activity	18/2342	167/18639	0.107784431137725	0.857811277530336	0.790325791155089	0.9651898553357
GO:0004402	histone acetyltransferase activity	4/2342	42/18639	0.0952380952380952	0.757960229352202	0.790999354275417	0.9651898553357
GO:0048487	beta-tubulin binding	4/2342	42/18639	0.0952380952380952	0.757960229352202	0.790999354275417	0.9651898553357
GO:0016651	oxidoreductase activity, acting on NAD(P)H	9/2342	88/18639	0.102272727272727	0.813945928111172	0.791548700979983	0.9651898553357
GO:0003720	telomerase activity	1/2342	12/18639	0.0833333333333333	0.663215200683177	0.800473955549951	0.9651898553357
GO:0004032	aldose reductase (NADPH) activity	1/2342	12/18639	0.0833333333333333	0.663215200683177	0.800473955549951	0.9651898553357
GO:0004126	cytidine deaminase activity	1/2342	12/18639	0.0833333333333333	0.663215200683177	0.800473955549951	0.9651898553357
GO:0004300	enoyl-CoA hydratase activity	1/2342	12/18639	0.0833333333333333	0.663215200683177	0.800473955549951	0.9651898553357
GO:0004859	phospholipase inhibitor activity	1/2342	12/18639	0.0833333333333333	0.663215200683177	0.800473955549951	0.9651898553357
GO:0005247	voltage-gated chloride channel activity	1/2342	12/18639	0.0833333333333333	0.663215200683177	0.800473955549951	0.9651898553357
GO:0005436	sodium:phosphate symporter activity	1/2342	12/18639	0.0833333333333333	0.663215200683177	0.800473955549951	0.9651898553357
GO:0016273	arginine N-methyltransferase activity	1/2342	12/18639	0.0833333333333333	0.663215200683177	0.800473955549951	0.9651898553357
GO:0016274	protein-arginine N-methyltransferase activity	1/2342	12/18639	0.0833333333333333	0.663215200683177	0.800473955549951	0.9651898553357
GO:0035197	siRNA binding	1/2342	12/18639	0.0833333333333333	0.663215200683177	0.800473955549951	0.9651898553357
GO:0035251	UDP-glucosyltransferase activity	1/2342	12/18639	0.0833333333333333	0.663215200683177	0.800473955549951	0.9651898553357
GO:0043047	single-stranded telomeric DNA binding	1/2342	12/18639	0.0833333333333333	0.663215200683177	0.800473955549951	0.9651898553357
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	1/2342	12/18639	0.0833333333333333	0.663215200683177	0.800473955549951	0.9651898553357
GO:0070008	serine-type exopeptidase activity	1/2342	12/18639	0.0833333333333333	0.663215200683177	0.800473955549951	0.9651898553357
GO:0097371	MDM2/MDM4 family protein binding	1/2342	12/18639	0.0833333333333333	0.663215200683177	0.800473955549951	0.9651898553357
GO:0106019	phosphatidylinositol-4,5-bisphosphate phosphatase activity	1/2342	12/18639	0.0833333333333333	0.663215200683177	0.800473955549951	0.9651898553357
GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	1/2342	12/18639	0.0833333333333333	0.663215200683177	0.800473955549951	0.9651898553357
GO:0140822	NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity	1/2342	12/18639	0.0833333333333333	0.663215200683177	0.800473955549951	0.9651898553357
GO:0140844	NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity	1/2342	12/18639	0.0833333333333333	0.663215200683177	0.800473955549951	0.9651898553357
GO:0140867	NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity	1/2342	12/18639	0.0833333333333333	0.663215200683177	0.800473955549951	0.9651898553357
GO:0015276	ligand-gated monoatomic ion channel activity	20/2342	186/18639	0.10752688172043	0.855761549268615	0.803420236017501	0.9651898553357
GO:0016917	GABA receptor activity	2/2342	23/18639	0.0869565217391304	0.692050644191141	0.803953366800021	0.9651898553357
GO:0042171	lysophosphatidic acid acyltransferase activity	2/2342	23/18639	0.0869565217391304	0.692050644191141	0.803953366800021	0.9651898553357
GO:0071617	lysophospholipid acyltransferase activity	2/2342	23/18639	0.0869565217391304	0.692050644191141	0.803953366800021	0.9651898553357
GO:0140103	catalytic activity, acting on a glycoprotein	2/2342	23/18639	0.0869565217391304	0.692050644191141	0.803953366800021	0.9651898553357
GO:0042393	histone binding	27/2342	247/18639	0.109311740890688	0.869966498062143	0.808229438882253	0.967873009038164
GO:0004864	protein phosphatase inhibitor activity	5/2342	53/18639	0.0943396226415094	0.750809661150766	0.81252546834977	0.967873009038164
GO:1901505	carbohydrate derivative transmembrane transporter activity	5/2342	53/18639	0.0943396226415094	0.750809661150766	0.81252546834977	0.967873009038164
GO:0022834	ligand-gated channel activity	20/2342	188/18639	0.106382978723404	0.8466577029998	0.817970331308174	0.967873009038164
GO:0140597	protein carrier chaperone	20/2342	188/18639	0.106382978723404	0.8466577029998	0.817970331308174	0.967873009038164
GO:0043014	alpha-tubulin binding	4/2342	44/18639	0.0909090909090909	0.723507491654375	0.820529386085423	0.967873009038164
GO:0015295	solute:proton symporter activity	2/2342	24/18639	0.0833333333333333	0.663215200683177	0.822886269597371	0.967873009038164
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	2/2342	24/18639	0.0833333333333333	0.663215200683177	0.822886269597371	0.967873009038164
GO:0048027	mRNA 5'-UTR binding	2/2342	24/18639	0.0833333333333333	0.663215200683177	0.822886269597371	0.967873009038164
GO:0050661	NADP binding	5/2342	54/18639	0.0925925925925926	0.736905778536863	0.82526479416738	0.967873009038164
GO:0003964	RNA-directed DNA polymerase activity	1/2342	13/18639	0.0769230769230769	0.612198646784471	0.825560657439789	0.967873009038164
GO:0004465	lipoprotein lipase activity	1/2342	13/18639	0.0769230769230769	0.612198646784471	0.825560657439789	0.967873009038164
GO:0004535	poly(A)-specific ribonuclease activity	1/2342	13/18639	0.0769230769230769	0.612198646784471	0.825560657439789	0.967873009038164
GO:0008253	5'-nucleotidase activity	1/2342	13/18639	0.0769230769230769	0.612198646784471	0.825560657439789	0.967873009038164
GO:0008417	fucosyltransferase activity	1/2342	13/18639	0.0769230769230769	0.612198646784471	0.825560657439789	0.967873009038164
GO:0015651	quaternary ammonium group transmembrane transporter activity	1/2342	13/18639	0.0769230769230769	0.612198646784471	0.825560657439789	0.967873009038164
GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors	1/2342	13/18639	0.0769230769230769	0.612198646784471	0.825560657439789	0.967873009038164
GO:0017154	semaphorin receptor activity	1/2342	13/18639	0.0769230769230769	0.612198646784471	0.825560657439789	0.967873009038164
GO:0019104	DNA N-glycosylase activity	1/2342	13/18639	0.0769230769230769	0.612198646784471	0.825560657439789	0.967873009038164
GO:0035325	Toll-like receptor binding	1/2342	13/18639	0.0769230769230769	0.612198646784471	0.825560657439789	0.967873009038164
GO:0046975	histone H3K36 methyltransferase activity	1/2342	13/18639	0.0769230769230769	0.612198646784471	0.825560657439789	0.967873009038164
GO:0070700	BMP receptor binding	1/2342	13/18639	0.0769230769230769	0.612198646784471	0.825560657439789	0.967873009038164
GO:0097157	pre-mRNA intronic binding	1/2342	13/18639	0.0769230769230769	0.612198646784471	0.825560657439789	0.967873009038164
GO:0140666	annealing activity	1/2342	13/18639	0.0769230769230769	0.612198646784471	0.825560657439789	0.967873009038164
GO:0140806	NAD+-protein-aspartate ADP-ribosyltransferase activity	1/2342	13/18639	0.0769230769230769	0.612198646784471	0.825560657439789	0.967873009038164
GO:0140852	histone ubiquitin ligase activity	1/2342	13/18639	0.0769230769230769	0.612198646784471	0.825560657439789	0.967873009038164
GO:0004521	RNA endonuclease activity	7/2342	73/18639	0.0958904109589041	0.763151737772423	0.827066090386412	0.968763617143326
GO:0004386	helicase activity	16/2342	155/18639	0.103225806451613	0.821531087297871	0.833136150561037	0.97289841381865
GO:0000175	3'-5'-RNA exonuclease activity	3/2342	35/18639	0.0857142857142857	0.682164206416982	0.833591943479721	0.97289841381865
GO:0005343	organic acid:sodium symporter activity	3/2342	35/18639	0.0857142857142857	0.682164206416982	0.833591943479721	0.97289841381865
GO:0140566	histone reader activity	3/2342	35/18639	0.0857142857142857	0.682164206416982	0.833591943479721	0.97289841381865
GO:0008374	O-acyltransferase activity	5/2342	55/18639	0.0909090909090909	0.723507491654375	0.837293185405221	0.97546533438689
GO:0140313	molecular sequestering activity	5/2342	55/18639	0.0909090909090909	0.723507491654375	0.837293185405221	0.97546533438689
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	2/2342	25/18639	0.08	0.63668659265585	0.840158903477586	0.977006716186013
GO:0017056	structural constituent of nuclear pore	2/2342	25/18639	0.08	0.63668659265585	0.840158903477586	0.977006716186013
GO:0004540	RNA nuclease activity	12/2342	121/18639	0.0991735537190083	0.789280899986591	0.846682693086895	0.977006716186013
GO:0005313	L-glutamate transmembrane transporter activity	1/2342	14/18639	0.0714285714285714	0.568470172014152	0.847494349068481	0.977006716186013
GO:0008474	palmitoyl-(protein) hydrolase activity	1/2342	14/18639	0.0714285714285714	0.568470172014152	0.847494349068481	0.977006716186013
GO:0015386	potassium:proton antiporter activity	1/2342	14/18639	0.0714285714285714	0.568470172014152	0.847494349068481	0.977006716186013
GO:0016530	metallochaperone activity	1/2342	14/18639	0.0714285714285714	0.568470172014152	0.847494349068481	0.977006716186013
GO:0030983	mismatched DNA binding	1/2342	14/18639	0.0714285714285714	0.568470172014152	0.847494349068481	0.977006716186013
GO:0034236	protein kinase A catalytic subunit binding	1/2342	14/18639	0.0714285714285714	0.568470172014152	0.847494349068481	0.977006716186013
GO:0098599	palmitoyl hydrolase activity	1/2342	14/18639	0.0714285714285714	0.568470172014152	0.847494349068481	0.977006716186013
GO:1990825	sequence-specific mRNA binding	1/2342	14/18639	0.0714285714285714	0.568470172014152	0.847494349068481	0.977006716186013
GO:0000993	RNA polymerase II complex binding	3/2342	36/18639	0.0833333333333333	0.663215200683177	0.847641700647911	0.977006716186013
GO:0019212	phosphatase inhibitor activity	5/2342	56/18639	0.0892857142857143	0.710587715017689	0.848633733445984	0.977282996229019
GO:0140658	ATP-dependent chromatin remodeler activity	16/2342	158/18639	0.10126582278481	0.805932395766898	0.854029871365834	0.980618792636928
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	12/2342	122/18639	0.0983606557377049	0.78281138441293	0.854293152698785	0.980618792636928
GO:0030507	spectrin binding	2/2342	26/18639	0.0769230769230769	0.612198646784471	0.855889382091724	0.980618792636928
GO:0120014	phospholipid transfer activity	2/2342	26/18639	0.0769230769230769	0.612198646784471	0.855889382091724	0.980618792636928
GO:0051536	iron-sulfur cluster binding	7/2342	76/18639	0.0921052631578947	0.73302732707088	0.856842289573337	0.980618792636928
GO:0099095	ligand-gated monoatomic anion channel activity	4/2342	47/18639	0.0851063829787234	0.67732616239984	0.85828652108952	0.980618792636928
GO:0030280	structural constituent of skin epidermis	3/2342	37/18639	0.0810810810810811	0.645290465529577	0.860647491967154	0.980618792636928
GO:0003724	RNA helicase activity	7/2342	77/18639	0.0909090909090909	0.723507491654375	0.865790079136981	0.980618792636928
GO:0051540	metal cluster binding	7/2342	77/18639	0.0909090909090909	0.723507491654375	0.865790079136981	0.980618792636928
GO:0004129	cytochrome-c oxidase activity	1/2342	15/18639	0.0666666666666667	0.530572160546541	0.866671167027226	0.980618792636928
GO:0004559	alpha-mannosidase activity	1/2342	15/18639	0.0666666666666667	0.530572160546541	0.866671167027226	0.980618792636928
GO:0005041	low-density lipoprotein particle receptor activity	1/2342	15/18639	0.0666666666666667	0.530572160546541	0.866671167027226	0.980618792636928
GO:0008020	G protein-coupled photoreceptor activity	1/2342	15/18639	0.0666666666666667	0.530572160546541	0.866671167027226	0.980618792636928
GO:0008252	nucleotidase activity	1/2342	15/18639	0.0666666666666667	0.530572160546541	0.866671167027226	0.980618792636928
GO:0015929	hexosaminidase activity	1/2342	15/18639	0.0666666666666667	0.530572160546541	0.866671167027226	0.980618792636928
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	1/2342	15/18639	0.0666666666666667	0.530572160546541	0.866671167027226	0.980618792636928
GO:0031386	protein tag activity	1/2342	15/18639	0.0666666666666667	0.530572160546541	0.866671167027226	0.980618792636928
GO:0042809	nuclear vitamin D receptor binding	1/2342	15/18639	0.0666666666666667	0.530572160546541	0.866671167027226	0.980618792636928
GO:0141047	molecular tag activity	1/2342	15/18639	0.0666666666666667	0.530572160546541	0.866671167027226	0.980618792636928
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	4/2342	48/18639	0.0833333333333333	0.663215200683177	0.869268392640289	0.980618792636928
GO:0001671	ATPase activator activity	2/2342	27/18639	0.0740740740740741	0.58952462282949	0.870192361817044	0.980618792636928
GO:0004364	glutathione transferase activity	2/2342	27/18639	0.0740740740740741	0.58952462282949	0.870192361817044	0.980618792636928
GO:0005104	fibroblast growth factor receptor binding	2/2342	27/18639	0.0740740740740741	0.58952462282949	0.870192361817044	0.980618792636928
GO:0030145	manganese ion binding	6/2342	68/18639	0.0882352941176471	0.702227859546893	0.871291749951618	0.980618792636928
GO:0022804	active transmembrane transporter activity	50/2342	457/18639	0.109409190371991	0.870742057789729	0.872358884451164	0.980618792636928
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	3/2342	38/18639	0.0789473684210526	0.628309137489325	0.872667686134171	0.980618792636928
GO:0042162	telomeric DNA binding	3/2342	38/18639	0.0789473684210526	0.628309137489325	0.872667686134171	0.980618792636928
GO:0042887	amide transmembrane transporter activity	3/2342	38/18639	0.0789473684210526	0.628309137489325	0.872667686134171	0.980618792636928
GO:0004197	cysteine-type endopeptidase activity	8/2342	88/18639	0.0909090909090909	0.723507491654375	0.877839059762487	0.985577302187961
GO:0008186	ATP-dependent activity, acting on RNA	7/2342	79/18639	0.0886075949367089	0.705190846296036	0.882307352983126	0.986745751007998
GO:0016835	carbon-oxygen lyase activity	7/2342	79/18639	0.0886075949367089	0.705190846296036	0.882307352983126	0.986745751007998
GO:0019789	SUMO transferase activity	2/2342	28/18639	0.0714285714285714	0.568470172014152	0.883178045834884	0.986745751007998
GO:0015923	mannosidase activity	1/2342	16/18639	0.0625	0.497411400512383	0.883437496860894	0.986745751007998
GO:0016675	oxidoreductase activity, acting on a heme group of donors	1/2342	16/18639	0.0625	0.497411400512383	0.883437496860894	0.986745751007998
GO:0043023	ribosomal large subunit binding	1/2342	16/18639	0.0625	0.497411400512383	0.883437496860894	0.986745751007998
GO:0016779	nucleotidyltransferase activity	13/2342	136/18639	0.0955882352941176	0.760746847842467	0.886583505949016	0.989408912566815
GO:0140713	histone chaperone activity	16/2342	164/18639	0.0975609756097561	0.776447064214451	0.889717706987174	0.992054335945355
GO:0004532	RNA exonuclease activity	3/2342	40/18639	0.075	0.596893680614859	0.893982007934956	0.995954226678823
GO:0005416	amino acid:monoatomic cation symporter activity	2/2342	29/18639	0.0689655172413793	0.548867752289526	0.894951492861074	0.996179939354358
GO:0016018	cyclosporin A binding	1/2342	17/18639	0.0588235294117647	0.468151906364595	0.898096218997595	0.997360435790071
GO:0030548	acetylcholine receptor regulator activity	1/2342	17/18639	0.0588235294117647	0.468151906364595	0.898096218997595	0.997360435790071
GO:0015399	primary active transmembrane transporter activity	16/2342	166/18639	0.0963855421686747	0.767092280308253	0.89992651930682	0.997360435790071
GO:0042287	MHC protein binding	3/2342	41/18639	0.0731707317073171	0.582335298160838	0.903388653337944	0.997360435790071
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	4/2342	52/18639	0.0769230769230769	0.612198646784471	0.906153971768743	0.997360435790071
GO:0000900	mRNA regulatory element binding translation repressor activity	1/2342	18/18639	0.0555555555555556	0.442143467122118	0.910912170834542	0.997360435790071
GO:0016854	racemase and epimerase activity	1/2342	18/18639	0.0555555555555556	0.442143467122118	0.910912170834542	0.997360435790071
GO:0022851	GABA-gated chloride ion channel activity	1/2342	18/18639	0.0555555555555556	0.442143467122118	0.910912170834542	0.997360435790071
GO:0030228	lipoprotein particle receptor activity	1/2342	18/18639	0.0555555555555556	0.442143467122118	0.910912170834542	0.997360435790071
GO:0032393	MHC class I receptor activity	1/2342	18/18639	0.0555555555555556	0.442143467122118	0.910912170834542	0.997360435790071
GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	1/2342	18/18639	0.0555555555555556	0.442143467122118	0.910912170834542	0.997360435790071
GO:0042056	chemoattractant activity	3/2342	42/18639	0.0714285714285714	0.568470172014152	0.912033984035062	0.997360435790071
GO:0043175	RNA polymerase core enzyme binding	3/2342	42/18639	0.0714285714285714	0.568470172014152	0.912033984035062	0.997360435790071
GO:0016860	intramolecular oxidoreductase activity	4/2342	53/18639	0.0754716981132075	0.600647728920613	0.913797114904986	0.997360435790071
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	12/2342	132/18639	0.0909090909090909	0.723507491654375	0.915063415986738	0.997360435790071
GO:0016411	acylglycerol O-acyltransferase activity	2/2342	31/18639	0.0645161290322581	0.513456929561169	0.915253697604396	0.997360435790071
GO:0072349	modified amino acid transmembrane transporter activity	2/2342	31/18639	0.0645161290322581	0.513456929561169	0.915253697604396	0.997360435790071
GO:0000510	H3-H4 histone complex chaperone activity	14/2342	151/18639	0.0927152317880795	0.73788181268062	0.916187135352181	0.997360435790071
GO:0140584	chromatin extrusion motor activity	14/2342	151/18639	0.0927152317880795	0.73788181268062	0.916187135352181	0.997360435790071
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	14/2342	151/18639	0.0927152317880795	0.73788181268062	0.916187135352181	0.997360435790071
GO:0140849	ATP-dependent H2AZ histone chaperone activity	14/2342	151/18639	0.0927152317880795	0.73788181268062	0.916187135352181	0.997360435790071
GO:0003678	DNA helicase activity	6/2342	74/18639	0.0810810810810811	0.645290465529577	0.916338988079008	0.997360435790071
GO:0003684	damaged DNA binding	6/2342	74/18639	0.0810810810810811	0.645290465529577	0.916338988079008	0.997360435790071
GO:0031491	nucleosome binding	6/2342	74/18639	0.0810810810810811	0.645290465529577	0.916338988079008	0.997360435790071
GO:0004536	DNA nuclease activity	5/2342	64/18639	0.078125	0.621764250640478	0.917637442721185	0.997360435790071
GO:0015616	DNA translocase activity	14/2342	152/18639	0.0921052631578947	0.73302732707088	0.920562892514813	0.997360435790071
GO:0140674	ATP-dependent histone chaperone activity	14/2342	152/18639	0.0921052631578947	0.73302732707088	0.920562892514813	0.997360435790071
GO:0017069	snRNA binding	4/2342	54/18639	0.0740740740740741	0.58952462282949	0.920879700563994	0.997360435790071
GO:0004890	GABA-A receptor activity	1/2342	19/18639	0.0526315789473684	0.418872758326217	0.922116923313222	0.997360435790071
GO:0008301	DNA binding, bending	1/2342	19/18639	0.0526315789473684	0.418872758326217	0.922116923313222	0.997360435790071
GO:0042834	peptidoglycan binding	1/2342	19/18639	0.0526315789473684	0.418872758326217	0.922116923313222	0.997360435790071
GO:0046527	glucosyltransferase activity	1/2342	19/18639	0.0526315789473684	0.418872758326217	0.922116923313222	0.997360435790071
GO:0070003	threonine-type peptidase activity	1/2342	19/18639	0.0526315789473684	0.418872758326217	0.922116923313222	0.997360435790071
GO:0097001	ceramide binding	1/2342	19/18639	0.0526315789473684	0.418872758326217	0.922116923313222	0.997360435790071
GO:0031369	translation initiation factor binding	2/2342	32/18639	0.0625	0.497411400512383	0.923963749968996	0.997696518046322
GO:0140142	nucleocytoplasmic carrier activity	2/2342	32/18639	0.0625	0.497411400512383	0.923963749968996	0.997696518046322
GO:0061775	cohesin loader activity	14/2342	153/18639	0.0915032679738562	0.728236298789371	0.924745335599894	0.997711122046729
GO:0004518	nuclease activity	20/2342	209/18639	0.0956937799043062	0.761586833320394	0.926447368941276	0.998717952078603
GO:0008094	ATP-dependent activity, acting on DNA	20/2342	210/18639	0.0952380952380952	0.757960229352202	0.929854606799532	1
GO:0042923	neuropeptide binding	2/2342	33/18639	0.0606060606060606	0.482338327769583	0.931824068749612	1
GO:0140311	protein sequestering activity	2/2342	33/18639	0.0606060606060606	0.482338327769583	0.931824068749612	1
GO:0015464	acetylcholine receptor activity	1/2342	20/18639	0.05	0.397929120409906	0.931912957985641	1
GO:0042288	MHC class I protein binding	1/2342	20/18639	0.05	0.397929120409906	0.931912957985641	1
GO:0015293	symporter activity	13/2342	146/18639	0.089041095890411	0.708640899360107	0.934333923725505	1
GO:0004519	endonuclease activity	11/2342	127/18639	0.0866141732283465	0.689326035355743	0.93497716315257	1
GO:0008175	tRNA methyltransferase activity	2/2342	34/18639	0.0588235294117647	0.468151906364595	0.938910570070458	1
GO:0035613	RNA stem-loop binding	1/2342	21/18639	0.0476190476190476	0.378980114676101	0.940477319787973	1
GO:1904047	S-adenosyl-L-methionine binding	1/2342	21/18639	0.0476190476190476	0.378980114676101	0.940477319787973	1
GO:0043021	ribonucleoprotein complex binding	16/2342	177/18639	0.0903954802259887	0.719419878707175	0.943154427796721	1
GO:0034061	DNA polymerase activity	2/2342	35/18639	0.0571428571428571	0.454776137611321	0.945293517136564	1
GO:0008093	cytoskeletal anchor activity	1/2342	22/18639	0.0454545454545455	0.361753745827187	0.947964811304601	1
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	1/2342	22/18639	0.0454545454545455	0.361753745827187	0.947964811304601	1
GO:0003689	DNA clamp loader activity	14/2342	160/18639	0.0875	0.696375960717336	0.949115744023669	1
GO:0004190	aspartic-type endopeptidase activity	2/2342	36/18639	0.0555555555555556	0.442143467122118	0.951037741635896	1
GO:0005231	excitatory extracellular ligand-gated monoatomic ion channel activity	2/2342	36/18639	0.0555555555555556	0.442143467122118	0.951037741635896	1
GO:0043022	ribosome binding	9/2342	112/18639	0.0803571428571429	0.63952894351592	0.951897118567431	1
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	4/2342	60/18639	0.0666666666666667	0.530572160546541	0.953411702721908	1
GO:0003887	DNA-directed DNA polymerase activity	1/2342	23/18639	0.0434782608695652	0.34602532209557	0.954510786054809	1
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	1/2342	23/18639	0.0434782608695652	0.34602532209557	0.954510786054809	1
GO:0005283	amino acid:sodium symporter activity	1/2342	23/18639	0.0434782608695652	0.34602532209557	0.954510786054809	1
GO:0070577	lysine-acetylated histone binding	1/2342	23/18639	0.0434782608695652	0.34602532209557	0.954510786054809	1
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	1/2342	23/18639	0.0434782608695652	0.34602532209557	0.954510786054809	1
GO:0022829	wide pore channel activity	2/2342	37/18639	0.0540540540540541	0.430193643686385	0.956202898759824	1
GO:0070001	aspartic-type peptidase activity	2/2342	37/18639	0.0540540540540541	0.430193643686385	0.956202898759824	1
GO:0042625	ATPase-coupled ion transmembrane transporter activity	1/2342	24/18639	0.0416666666666667	0.331607600341588	0.960233591118176	1
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	1/2342	24/18639	0.0416666666666667	0.331607600341588	0.960233591118176	1
GO:0046961	proton-transporting ATPase activity, rotational mechanism	1/2342	24/18639	0.0416666666666667	0.331607600341588	0.960233591118176	1
GO:0070840	dynein complex binding	1/2342	24/18639	0.0416666666666667	0.331607600341588	0.960233591118176	1
GO:0140033	acetylation-dependent protein binding	1/2342	24/18639	0.0416666666666667	0.331607600341588	0.960233591118176	1
GO:0005230	extracellular ligand-gated monoatomic ion channel activity	5/2342	73/18639	0.0684931506849315	0.545108384123159	0.960733133012271	1
GO:0004527	exonuclease activity	6/2342	84/18639	0.0714285714285714	0.568470172014152	0.961364057351773	1
GO:0003743	translation initiation factor activity	3/2342	51/18639	0.0588235294117647	0.468151906364595	0.963386615339252	1
GO:0022824	transmitter-gated monoatomic ion channel activity	4/2342	63/18639	0.0634920634920635	0.505306819568135	0.964567442402364	1
GO:0022835	transmitter-gated channel activity	4/2342	63/18639	0.0634920634920635	0.505306819568135	0.964567442402364	1
GO:0015662	P-type ion transporter activity	1/2342	25/18639	0.04	0.318343296327925	0.9652367031032	1
GO:0017025	TBP-class protein binding	1/2342	25/18639	0.04	0.318343296327925	0.9652367031032	1
GO:0140358	P-type transmembrane transporter activity	1/2342	25/18639	0.04	0.318343296327925	0.9652367031032	1
GO:0030594	neurotransmitter receptor activity	7/2342	97/18639	0.0721649484536082	0.574330689251411	0.967951723472906	1
GO:0140101	catalytic activity, acting on a tRNA	11/2342	139/18639	0.079136690647482	0.629815874030067	0.969792924638623	1
GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	3/2342	53/18639	0.0566037735849057	0.45048579669046	0.97007626713172	1
GO:0004812	aminoacyl-tRNA ligase activity	2/2342	41/18639	0.0487804878048781	0.388223532107225	0.972100559451188	1
GO:0008137	NADH dehydrogenase (ubiquinone) activity	2/2342	41/18639	0.0487804878048781	0.388223532107225	0.972100559451188	1
GO:0016875	ligase activity, forming carbon-oxygen bonds	2/2342	41/18639	0.0487804878048781	0.388223532107225	0.972100559451188	1
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	3/2342	54/18639	0.0555555555555556	0.442143467122118	0.972970182812175	1
GO:0015252	proton channel activity	1/2342	27/18639	0.037037037037037	0.294762311414745	0.973434374179298	1
GO:0004520	DNA endonuclease activity	2/2342	42/18639	0.0476190476190476	0.378980114676101	0.975103888221995	1
GO:0031492	nucleosomal DNA binding	2/2342	42/18639	0.0476190476190476	0.378980114676101	0.975103888221995	1
GO:0015370	solute:sodium symporter activity	5/2342	79/18639	0.0632911392405063	0.503707747354312	0.976686620649442	1
GO:0016866	intramolecular transferase activity	1/2342	28/18639	0.0357142857142857	0.284235086007076	0.976777201155018	1
GO:0046625	sphingolipid binding	1/2342	28/18639	0.0357142857142857	0.284235086007076	0.976777201155018	1
GO:0051537	2 iron, 2 sulfur cluster binding	1/2342	28/18639	0.0357142857142857	0.284235086007076	0.976777201155018	1
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	4/2342	68/18639	0.0588235294117647	0.468151906364595	0.977806542764933	1
GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	3/2342	56/18639	0.0535714285714286	0.426352629010614	0.97798020245146	1
GO:0003823	antigen binding	14/2342	174/18639	0.0804597701149425	0.640345711004446	0.978142220555142	1
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	6/2342	91/18639	0.0659340659340659	0.524741697243832	0.978273443381047	1
GO:0000049	tRNA binding	5/2342	80/18639	0.0625	0.497411400512383	0.978667374936193	1
GO:0051861	glycolipid binding	1/2342	29/18639	0.0344827586206897	0.274433876144763	0.979699547879801	1
GO:0098960	postsynaptic neurotransmitter receptor activity	4/2342	69/18639	0.0579710144927536	0.461367096127427	0.979821547348596	1
GO:0003954	NADH dehydrogenase activity	2/2342	44/18639	0.0454545454545455	0.361753745827187	0.980200369695852	1
GO:0008106	alcohol dehydrogenase (NADP+) activity	1/2342	30/18639	0.0333333333333333	0.265286080273271	0.982254285056884	1
GO:0009055	electron transfer activity	8/2342	116/18639	0.0689655172413793	0.548867752289526	0.983235865834657	1
GO:0015294	solute:monoatomic cation symporter activity	8/2342	116/18639	0.0689655172413793	0.548867752289526	0.983235865834657	1
GO:0036002	pre-mRNA binding	3/2342	59/18639	0.0508474576271186	0.404673681772786	0.983869121188395	1
GO:0180051	translation factor activity	5/2342	84/18639	0.0595238095238095	0.473725143345126	0.985119323292332	1
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	3/2342	61/18639	0.0491803278688525	0.391405692206465	0.986921670637053	1
GO:0008188	neuropeptide receptor activity	2/2342	48/18639	0.0416666666666667	0.331607600341588	0.987534512657591	1
GO:0038187	pattern recognition receptor activity	2/2342	48/18639	0.0416666666666667	0.331607600341588	0.987534512657591	1
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	1/2342	33/18639	0.0303030303030303	0.241169163884792	0.988146769978006	1
GO:0016891	RNA endonuclease activity, producing 5'-phosphomonoesters	1/2342	34/18639	0.0294117647058824	0.234075953182298	0.989638776035811	1
GO:0004033	aldo-keto reductase (NADPH) activity	1/2342	36/18639	0.0277777777777778	0.221071733561059	0.992083199976962	1
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	1/2342	36/18639	0.0277777777777778	0.221071733561059	0.992083199976962	1
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	1/2342	36/18639	0.0277777777777778	0.221071733561059	0.992083199976962	1
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	1/2342	36/18639	0.0277777777777778	0.221071733561059	0.992083199976962	1
GO:0016853	isomerase activity	13/2342	180/18639	0.0722222222222222	0.574786507258753	0.992608793846033	1
GO:0016251	RNA polymerase II general transcription initiation factor activity	2/2342	53/18639	0.0377358490566038	0.300323864460306	0.993061872617587	1
GO:0008173	RNA methyltransferase activity	3/2342	67/18639	0.0447761194029851	0.356354436187976	0.993099291413227	1
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	1/2342	39/18639	0.0256410256410256	0.204066215594824	0.994712719171219	1
GO:0015078	proton transmembrane transporter activity	13/2342	185/18639	0.0702702702702703	0.5592517367923	0.994830038056146	1
GO:0008135	translation factor activity, RNA binding	4/2342	83/18639	0.0481927710843374	0.383546140154126	0.994927841537067	1
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	2/2342	58/18639	0.0344827586206897	0.274433876144763	0.996165923341966	1
GO:0016859	cis-trans isomerase activity	1/2342	42/18639	0.0238095238095238	0.18949005733805	0.99646910492878	1
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	1/2342	43/18639	0.0232558139534884	0.185083311818561	0.996913765694323	1
GO:0140097	catalytic activity, acting on DNA	27/2342	336/18639	0.0803571428571429	0.63952894351592	0.997050257238467	1
GO:0003730	mRNA 3'-UTR binding	19/2342	262/18639	0.0725190839694656	0.577149105938032	0.998081157014402	1
GO:0022853	active monoatomic ion transmembrane transporter activity	6/2342	118/18639	0.0508474576271186	0.404673681772786	0.998081662450804	1
GO:0019843	rRNA binding	2/2342	65/18639	0.0307692307692308	0.244879458713788	0.998345554517399	1
GO:0140223	general transcription initiation factor activity	2/2342	68/18639	0.0294117647058824	0.234075953182298	0.998849569649215	1
GO:0140098	catalytic activity, acting on RNA	30/2342	387/18639	0.0775193798449612	0.616944372728537	0.999164182346986	1
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	1/2342	60/18639	0.0166666666666667	0.132643040136635	0.999687274596363	1
GO:0003735	structural constituent of ribosome	2/2342	175/18639	0.0114285714285714	0.0909552275222642	0.999999998536146	1
GO:0045182	translation regulator activity	8/2342	356/18639	0.0224719101123595	0.178844548498834	0.999999999999758	1
GO:0030371	translation repressor activity	3/2342	329/18639	0.00911854103343465	0.0725706602571257	1	1