ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0045296 cadherin binding 48/573 334/18639 0.143712574850299 4.67479700285293 3.61219026869154e-19 3.07758610892519e-16 GO:0003779 actin binding 44/573 443/18639 0.0993227990970655 3.2308510512569 7.59539487637671e-12 3.23563821733648e-09 GO:0098632 cell-cell adhesion mediator activity 15/573 55/18639 0.272727272727273 8.87148976677772 6.59823846395063e-11 1.87389972376198e-08 GO:0098641 cadherin binding involved in cell-cell adhesion 9/573 18/18639 0.5 16.2643979057592 8.74883361754744e-10 1.72996765220744e-07 GO:0098631 cell adhesion mediator activity 16/573 76/18639 0.210526315789474 6.84816753926702 1.01523923251611e-09 1.72996765220744e-07 GO:0051015 actin filament binding 23/573 209/18639 0.110047846889952 3.57972394098049 1.3066411414058e-07 1.85543042079624e-05 GO:0019838 growth factor binding 16/573 136/18639 0.117647058823529 3.82691715429627 4.46399300182397e-06 0.000543331719650575 GO:0008201 heparin binding 18/573 172/18639 0.104651162790698 3.40417630585657 6.1573103255279e-06 0.000655753549668721 GO:0005178 integrin binding 17/573 161/18639 0.105590062111801 3.43471757016032 9.85273767286567e-06 0.000932725833031283 GO:0005539 glycosaminoglycan binding 21/573 242/18639 0.0867768595041322 2.82274674397473 2.00180548355604e-05 0.00170553827198975 GO:0086080 protein binding involved in heterotypic cell-cell adhesion 5/573 13/18639 0.384615384615385 12.5110753121224 2.82945016878917e-05 0.00213587999900578 GO:0010314 phosphatidylinositol-5-phosphate binding 6/573 21/18639 0.285714285714286 9.29394166043381 3.00828168874054e-05 0.00213587999900578 GO:0004866 endopeptidase inhibitor activity 16/573 161/18639 0.0993788819875776 3.23267536015089 3.79685778532952e-05 0.00248840217930827 GO:0005161 platelet-derived growth factor receptor binding 5/573 14/18639 0.357142857142857 11.6174270755423 4.29020303817731e-05 0.00261089499180505 GO:0030414 peptidase inhibitor activity 16/573 169/18639 0.0946745562130177 3.07964930759937 6.8346622059606e-05 0.003682389435134 GO:0005543 phospholipid binding 32/573 497/18639 0.0643863179074447 2.09440938826677 7.24350541985502e-05 0.003682389435134 GO:0045309 protein phosphorylated amino acid binding 9/573 59/18639 0.152542372881356 4.96201970006212 7.34749065695751e-05 0.003682389435134 GO:0055102 lipase inhibitor activity 5/573 16/18639 0.3125 10.1652486910995 8.89409639798174e-05 0.00420987229504469 GO:0051020 GTPase binding 23/573 315/18639 0.073015873015873 2.37511842433308 0.000121852516140623 0.00518815393776401 GO:1901681 sulfur compound binding 21/573 275/18639 0.0763636363636364 2.48401713469776 0.000127907373329722 0.00518815393776401 GO:0051219 phosphoprotein binding 11/573 93/18639 0.118279569892473 3.84749197770647 0.000131154552606259 0.00518815393776401 GO:0019199 transmembrane receptor protein kinase activity 10/573 78/18639 0.128205128205128 4.17035843737414 0.000133966416233343 0.00518815393776401 GO:0035591 signaling adaptor activity 13/573 129/18639 0.10077519379845 3.27809570193596 0.00017304936232299 0.00641035029126904 GO:0061135 endopeptidase regulator activity 16/573 184/18639 0.0869565217391304 2.82859094013203 0.000185680953455411 0.0065916738476671 GO:0005201 extracellular matrix structural constituent 15/573 168/18639 0.0892857142857143 2.90435676888556 0.000219245421677904 0.00718723010714081 GO:0005520 insulin-like growth factor binding 5/573 19/18639 0.263157894736842 8.56020942408377 0.000219328618293029 0.00718723010714081 GO:0141003 histone H2AX kinase activity 24/573 354/18639 0.0677966101694915 2.2053420889165 0.000267852653727992 0.00845223929541664 GO:0005085 guanyl-nucleotide exchange factor activity 18/573 230/18639 0.0782608695652174 2.54573184611883 0.000282280789617052 0.00858940116977602 GO:0140996 histone H3 kinase activity 24/573 357/18639 0.0672268907563025 2.18680980245501 0.000303162425956116 0.00890670299705555 GO:0035173 histone kinase activity 24/573 360/18639 0.0666666666666667 2.16858638743456 0.000342511141663946 0.00972731642325606 GO:1990247 N6-methyladenosine-containing RNA reader activity 4/573 12/18639 0.333333333333333 10.8429319371728 0.000359336608632614 0.00987596098564474 GO:0031267 small GTPase binding 20/573 283/18639 0.0706713780918728 2.29885482766914 0.000503531105338748 0.0126914529917075 GO:0031994 insulin-like growth factor I binding 4/573 13/18639 0.307692307692308 10.0088602496979 0.000506466433941379 0.0126914529917075 GO:0043560 insulin receptor substrate binding 4/573 13/18639 0.307692307692308 10.0088602496979 0.000506466433941379 0.0126914529917075 GO:0004857 enzyme inhibitor activity 26/573 416/18639 0.0625 2.0330497382199 0.000529471683544869 0.0127995747627902 GO:0001784 phosphotyrosine residue binding 7/573 47/18639 0.148936170212766 4.8447142698006 0.000540827102653105 0.0127995747627902 GO:0032266 phosphatidylinositol-3-phosphate binding 7/573 48/18639 0.145833333333333 4.74378272251309 0.00061662314974103 0.0141989979345772 GO:0061134 peptidase regulator activity 17/573 226/18639 0.0752212389380531 2.44685632210536 0.000648653188113432 0.0145434872703327 GO:0004867 serine-type endopeptidase inhibitor activity 10/573 95/18639 0.105263157894737 3.42408376963351 0.00067557349548907 0.0147586825168382 GO:0070300 phosphatidic acid binding 5/573 24/18639 0.208333333333333 6.77683246073298 0.000706007891100512 0.0150379680804409 GO:0043394 proteoglycan binding 6/573 37/18639 0.162162162162162 5.2749398613273 0.000848834466821375 0.017501526620935 GO:0004725 protein tyrosine phosphatase activity 10/573 98/18639 0.102040816326531 3.31926487872636 0.000862751312299612 0.017501526620935 GO:0005010 insulin-like growth factor receptor activity 7/573 51/18639 0.137254901960784 4.46473668001232 0.000895636744528717 0.017746104798569 GO:0140272 exogenous protein binding 9/573 82/18639 0.109756097560976 3.57023368663006 0.000917643499286684 0.0177689150316422 GO:0050840 extracellular matrix binding 8/573 67/18639 0.119402985074627 3.88403532077831 0.00100512333857645 0.0190303352103807 GO:0005160 transforming growth factor beta receptor binding 5/573 26/18639 0.192307692307692 6.25553765606122 0.00103860496569156 0.0192367702341132 GO:0030246 carbohydrate binding 19/573 280/18639 0.0678571428571429 2.20731114435303 0.0011177478947617 0.0200769991876321 GO:0038064 collagen receptor activity 7/573 53/18639 0.132075471698113 4.29625605057789 0.00113109854578209 0.0200769991876321 GO:0030695 GTPase regulator activity 28/573 489/18639 0.0572597137014315 1.86258953521986 0.00126923942454373 0.0220692242798216 GO:0060589 nucleoside-triphosphatase regulator activity 28/573 490/18639 0.0571428571428571 1.85878833208676 0.00130826432433 0.0222928240865831 GO:0045499 chemorepellent activity 5/573 28/18639 0.178571428571429 5.80871353777113 0.00147514218530913 0.0246435518016349 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 9/573 89/18639 0.101123595505618 3.28942878992882 0.00164743866676629 0.0264833536619788 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 9/573 89/18639 0.101123595505618 3.28942878992882 0.00164743866676629 0.0264833536619788 GO:0140793 histone H2AXY142 phosphatase activity 9/573 90/18639 0.1 3.25287958115183 0.00178177144583313 0.0277805760604322 GO:0004679 AMP-activated protein kinase activity 17/573 248/18639 0.0685483870967742 2.22979648707989 0.00179334704615466 0.0277805760604322 GO:0070064 proline-rich region binding 4/573 18/18639 0.222222222222222 7.22862129144852 0.00191813716902484 0.029183086928735 GO:0004674 protein serine/threonine kinase activity 25/573 433/18639 0.0577367205542725 1.87810599373662 0.00202465810241948 0.0302633105835333 GO:0004714 transmembrane receptor protein tyrosine kinase activity 7/573 60/18639 0.116666666666667 3.79502617801047 0.00235662776544646 0.033818133912732 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 4/573 19/18639 0.210526315789474 6.84816753926702 0.00237115278255332 0.033818133912732 GO:0005200 structural constituent of cytoskeleton 10/573 112/18639 0.0892857142857143 2.90435676888556 0.00238155872624873 0.033818133912732 GO:0001221 transcription coregulator binding 10/573 115/18639 0.0869565217391304 2.82859094013203 0.00289145196450724 0.034468245271788 GO:0046332 SMAD binding 8/573 79/18639 0.10126582278481 3.29405527205249 0.00291852046066681 0.034468245271788 GO:0001618 virus receptor activity 8/573 81/18639 0.0987654320987654 3.21272057397712 0.00341169054426407 0.034468245271788 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 16/573 243/18639 0.065843621399177 2.14181371598475 0.00359249584181845 0.034468245271788 GO:0005004 GPI-linked ephrin receptor activity 6/573 49/18639 0.122448979591837 3.98311785447163 0.00374294310553525 0.034468245271788 GO:0005008 hepatocyte growth factor receptor activity 6/573 49/18639 0.122448979591837 3.98311785447163 0.00374294310553525 0.034468245271788 GO:0005009 insulin receptor activity 6/573 49/18639 0.122448979591837 3.98311785447163 0.00374294310553525 0.034468245271788 GO:0005011 macrophage colony-stimulating factor receptor activity 6/573 49/18639 0.122448979591837 3.98311785447163 0.00374294310553525 0.034468245271788 GO:0005018 platelet-derived growth factor alpha-receptor activity 6/573 49/18639 0.122448979591837 3.98311785447163 0.00374294310553525 0.034468245271788 GO:0005020 stem cell factor receptor activity 6/573 49/18639 0.122448979591837 3.98311785447163 0.00374294310553525 0.034468245271788 GO:0008288 boss receptor activity 6/573 49/18639 0.122448979591837 3.98311785447163 0.00374294310553525 0.034468245271788 GO:0036332 placental growth factor receptor activity 6/573 49/18639 0.122448979591837 3.98311785447163 0.00374294310553525 0.034468245271788 GO:0038062 protein tyrosine kinase collagen receptor activity 6/573 49/18639 0.122448979591837 3.98311785447163 0.00374294310553525 0.034468245271788 GO:0060175 brain-derived neurotrophic factor receptor activity 6/573 49/18639 0.122448979591837 3.98311785447163 0.00374294310553525 0.034468245271788 GO:0004676 3-phosphoinositide-dependent protein kinase activity 16/573 245/18639 0.0653061224489796 2.12432952238487 0.00388997730436164 0.034468245271788 GO:0004711 ribosomal protein S6 kinase activity 16/573 245/18639 0.0653061224489796 2.12432952238487 0.00388997730436164 0.034468245271788 GO:0035175 histone H3S10 kinase activity 16/573 245/18639 0.0653061224489796 2.12432952238487 0.00388997730436164 0.034468245271788 GO:0035979 histone H2AXS139 kinase activity 16/573 245/18639 0.0653061224489796 2.12432952238487 0.00388997730436164 0.034468245271788 GO:0044022 histone H3S28 kinase activity 16/573 245/18639 0.0653061224489796 2.12432952238487 0.00388997730436164 0.034468245271788 GO:0044023 histone H4S1 kinase activity 16/573 245/18639 0.0653061224489796 2.12432952238487 0.00388997730436164 0.034468245271788 GO:0044024 histone H2AS1 kinase activity 16/573 245/18639 0.0653061224489796 2.12432952238487 0.00388997730436164 0.034468245271788 GO:0044025 histone H2BS14 kinase activity 16/573 245/18639 0.0653061224489796 2.12432952238487 0.00388997730436164 0.034468245271788 GO:0072354 histone H3T3 kinase activity 16/573 245/18639 0.0653061224489796 2.12432952238487 0.00388997730436164 0.034468245271788 GO:0072371 histone H2AS121 kinase activity 16/573 245/18639 0.0653061224489796 2.12432952238487 0.00388997730436164 0.034468245271788 GO:0072518 Rho-dependent protein serine/threonine kinase activity 16/573 245/18639 0.0653061224489796 2.12432952238487 0.00388997730436164 0.034468245271788 GO:0140823 histone H2BS36 kinase activity 16/573 245/18639 0.0653061224489796 2.12432952238487 0.00388997730436164 0.034468245271788 GO:0140855 histone H3S57 kinase activity 16/573 245/18639 0.0653061224489796 2.12432952238487 0.00388997730436164 0.034468245271788 GO:0140995 histone H2A kinase activity 16/573 245/18639 0.0653061224489796 2.12432952238487 0.00388997730436164 0.034468245271788 GO:0140997 histone H4 kinase activity 16/573 245/18639 0.0653061224489796 2.12432952238487 0.00388997730436164 0.034468245271788 GO:0140998 histone H2B kinase activity 16/573 245/18639 0.0653061224489796 2.12432952238487 0.00388997730436164 0.034468245271788 GO:1990244 histone H2AT120 kinase activity 16/573 245/18639 0.0653061224489796 2.12432952238487 0.00388997730436164 0.034468245271788 GO:0003953 NAD+ nucleosidase activity 3/573 11/18639 0.272727272727273 8.87148976677772 0.0039653724718252 0.034468245271788 GO:0045294 alpha-catenin binding 3/573 11/18639 0.272727272727273 8.87148976677772 0.0039653724718252 0.034468245271788 GO:0048185 activin binding 3/573 11/18639 0.272727272727273 8.87148976677772 0.0039653724718252 0.034468245271788 GO:0097493 structural molecule activity conferring elasticity 3/573 11/18639 0.272727272727273 8.87148976677772 0.0039653724718252 0.034468245271788 GO:0004677 DNA-dependent protein kinase activity 16/573 246/18639 0.0650406504065041 2.11569403652152 0.00404613238058824 0.034468245271788 GO:0140857 histone H3T45 kinase activity 16/573 246/18639 0.0650406504065041 2.11569403652152 0.00404613238058824 0.034468245271788 GO:0005006 epidermal growth factor receptor activity 6/573 50/18639 0.12 3.9034554973822 0.00414515326614058 0.034468245271788 GO:0005007 fibroblast growth factor receptor activity 6/573 50/18639 0.12 3.9034554973822 0.00414515326614058 0.034468245271788 GO:0005017 platelet-derived growth factor receptor activity 6/573 50/18639 0.12 3.9034554973822 0.00414515326614058 0.034468245271788 GO:0005019 platelet-derived growth factor beta-receptor activity 6/573 50/18639 0.12 3.9034554973822 0.00414515326614058 0.034468245271788 GO:0140517 protein-RNA adaptor activity 4/573 22/18639 0.181818181818182 5.91432651118515 0.00416019323389875 0.034468245271788 GO:0035402 histone H3T11 kinase activity 16/573 247/18639 0.0647773279352227 2.10712847362062 0.0042073914416267 0.034468245271788 GO:0035403 histone H3T6 kinase activity 16/573 247/18639 0.0647773279352227 2.10712847362062 0.0042073914416267 0.034468245271788 GO:0016500 protein-hormone receptor activity 7/573 67/18639 0.104477611940299 3.39853090568102 0.00441576774448541 0.0358308011266816 GO:0005021 vascular endothelial growth factor receptor activity 6/573 51/18639 0.117647058823529 3.82691715429627 0.00457842213568883 0.0364562211178213 GO:0005030 neurotrophin receptor activity 6/573 51/18639 0.117647058823529 3.82691715429627 0.00457842213568883 0.0364562211178213 GO:0004869 cysteine-type endopeptidase inhibitor activity 5/573 36/18639 0.138888888888889 4.51788830715532 0.00462500326564534 0.0364861368734244 GO:1901981 phosphatidylinositol phosphate binding 13/573 185/18639 0.0702702702702703 2.28580727324183 0.00482770435484907 0.0377284797641254 GO:0005158 insulin receptor binding 4/573 23/18639 0.173913043478261 5.65718188026406 0.00491533011011493 0.0377284797641254 GO:0005283 amino acid:sodium symporter activity 4/573 23/18639 0.173913043478261 5.65718188026406 0.00491533011011493 0.0377284797641254 GO:0030159 signaling receptor complex adaptor activity 6/573 52/18639 0.115384615384615 3.75332259363673 0.00504413266095124 0.0382835785316675 GO:0005078 MAP-kinase scaffold activity 3/573 12/18639 0.25 8.13219895287958 0.00516738442622273 0.0382835785316675 GO:0005527 macrolide binding 3/573 12/18639 0.25 8.13219895287958 0.00516738442622273 0.0382835785316675 GO:0045295 gamma-catenin binding 3/573 12/18639 0.25 8.13219895287958 0.00516738442622273 0.0382835785316675 GO:0005003 ephrin receptor activity 6/573 53/18639 0.113207547169811 3.68250518620962 0.00554366893097283 0.040027168891431 GO:0005005 transmembrane-ephrin receptor activity 6/573 53/18639 0.113207547169811 3.68250518620962 0.00554366893097283 0.040027168891431 GO:0005544 calcium-dependent phospholipid binding 6/573 53/18639 0.113207547169811 3.68250518620962 0.00554366893097283 0.040027168891431 GO:0030215 semaphorin receptor binding 4/573 24/18639 0.166666666666667 5.42146596858639 0.00575719455391782 0.0408760813328165 GO:0050431 transforming growth factor beta binding 4/573 24/18639 0.166666666666667 5.42146596858639 0.00575719455391782 0.0408760813328165 GO:0019209 kinase activator activity 11/573 148/18639 0.0743243243243243 2.41768076977501 0.00608282229438585 0.0428311123538574 GO:0043548 phosphatidylinositol 3-kinase binding 4/573 26/18639 0.153846153846154 5.00443012484897 0.00771742726032048 0.0534573010227077 GO:0070412 R-SMAD binding 4/573 26/18639 0.153846153846154 5.00443012484897 0.00771742726032048 0.0534573010227077 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 5/573 41/18639 0.121951219512195 3.96692631847784 0.00811058248000881 0.0556703374023351 GO:0044548 S100 protein binding 3/573 14/18639 0.214285714285714 6.97045624532536 0.0081675964498731 0.0556703374023351 GO:0106310 protein serine kinase activity 20/573 361/18639 0.0554016620498615 1.80214935243869 0.00843865410937848 0.0570613754062735 GO:0002020 protease binding 10/573 136/18639 0.0735294117647059 2.39182322143517 0.00934605624678168 0.0622096868926405 GO:0044325 transmembrane transporter binding 10/573 136/18639 0.0735294117647059 2.39182322143517 0.00934605624678168 0.0622096868926405 GO:0047372 monoacylglycerol lipase activity 3/573 15/18639 0.2 6.50575916230367 0.00997932585007633 0.0656738624917945 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 4/573 28/18639 0.142857142857143 4.6469708302169 0.0100715053060869 0.0656738624917945 GO:1990782 protein tyrosine kinase binding 9/573 117/18639 0.0769230769230769 2.50221506242449 0.0100977417681045 0.0656738624917945 GO:0030295 protein kinase activator activity 10/573 139/18639 0.0719424460431655 2.3402011375193 0.0108036037941473 0.0697323517622235 GO:0001223 transcription coactivator binding 5/573 44/18639 0.113636363636364 3.69645406949072 0.0109049412772434 0.0698572178061005 GO:0005416 amino acid:monoatomic cation symporter activity 4/573 29/18639 0.137931034482759 4.48673045676115 0.0114048723120517 0.0719774163693928 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 4/573 29/18639 0.137931034482759 4.48673045676115 0.0114048723120517 0.0719774163693928 GO:0005024 transforming growth factor beta receptor activity 3/573 16/18639 0.1875 6.09914921465969 0.0120058030129969 0.0735895263818229 GO:0022858 alanine transmembrane transporter activity 3/573 16/18639 0.1875 6.09914921465969 0.0120058030129969 0.0735895263818229 GO:0061809 NAD+ nucleosidase activity, cyclic ADP-ribose generating 3/573 16/18639 0.1875 6.09914921465969 0.0120058030129969 0.0735895263818229 GO:0070411 I-SMAD binding 3/573 16/18639 0.1875 6.09914921465969 0.0120058030129969 0.0735895263818229 GO:0001968 fibronectin binding 4/573 30/18639 0.133333333333333 4.33717277486911 0.0128466177559481 0.0781808452004843 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 3/573 17/18639 0.176470588235294 5.74037573144441 0.0142508911741621 0.0846099181616427 GO:0019198 transmembrane receptor protein phosphatase activity 3/573 17/18639 0.176470588235294 5.74037573144441 0.0142508911741621 0.0846099181616427 GO:0043495 protein-membrane adaptor activity 5/573 47/18639 0.106382978723404 3.46051019271472 0.0142934537816861 0.0846099181616427 GO:0070273 phosphatidylinositol-4-phosphate binding 4/573 31/18639 0.129032258064516 4.19726397567978 0.0143995752739885 0.0846099181616427 GO:0070325 lipoprotein particle receptor binding 4/573 31/18639 0.129032258064516 4.19726397567978 0.0143995752739885 0.0846099181616427 GO:0035091 phosphatidylinositol binding 16/573 284/18639 0.0563380281690141 1.83260821473343 0.0149967180216093 0.0875150942082954 GO:0016209 antioxidant activity 7/573 86/18639 0.0813953488372093 2.64769268233289 0.0166287996689892 0.0962382470463611 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 3/573 18/18639 0.166666666666667 5.42146596858639 0.0167174419751895 0.0962382470463611 GO:0043395 heparan sulfate proteoglycan binding 3/573 19/18639 0.157894736842105 5.13612565445026 0.0194073711988088 0.110707146676658 GO:0004721 phosphoprotein phosphatase activity 11/573 175/18639 0.0628571428571429 2.04466716529544 0.0196358354519286 0.110707146676658 GO:0008376 acetylgalactosaminyltransferase activity 4/573 34/18639 0.117647058823529 3.82691715429627 0.0197505707686056 0.110707146676658 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 4/573 34/18639 0.117647058823529 3.82691715429627 0.0197505707686056 0.110707146676658 GO:0005179 hormone activity 9/573 132/18639 0.0681818181818182 2.21787244169443 0.0208157618233008 0.115915222702302 GO:1902936 phosphatidylinositol bisphosphate binding 8/573 111/18639 0.0720720720720721 2.34441771614546 0.0212084176115799 0.117334881851079 GO:0005343 organic acid:sodium symporter activity 4/573 35/18639 0.114285714285714 3.71757666417352 0.0217720614975635 0.119676105780155 GO:0016791 phosphatase activity 15/573 273/18639 0.0549450549450549 1.78729647316035 0.0221444206763606 0.120942605232431 GO:0031418 L-ascorbic acid binding 3/573 20/18639 0.15 4.87931937172775 0.0223217302916256 0.121134485404236 GO:0017046 peptide hormone binding 5/573 53/18639 0.0943396226415094 3.06875432184135 0.0230414915037616 0.124249055450664 GO:0005518 collagen binding 6/573 72/18639 0.0833333333333333 2.71073298429319 0.0232267306628963 0.124460217137029 GO:0005126 cytokine receptor binding 15/573 275/18639 0.0545454545454545 1.77429795335554 0.0234525020232573 0.124884573273845 GO:0140789 histone phosphatase activity 9/573 136/18639 0.0661764705882353 2.15264089929165 0.0247011480045023 0.130716634160472 GO:0035401 histone H3Y41 kinase activity 8/573 115/18639 0.0695652173913043 2.26287275210562 0.0255870910599924 0.133743567994562 GO:0140801 histone H2AXY142 kinase activity 8/573 115/18639 0.0695652173913043 2.26287275210562 0.0255870910599924 0.133743567994562 GO:0042562 hormone binding 7/573 94/18639 0.074468085106383 2.4223571349003 0.0257601291625753 0.133827012478745 GO:0048029 monosaccharide binding 6/573 74/18639 0.0810810810810811 2.63746993066365 0.0261791421163593 0.135179570200837 GO:0004713 protein tyrosine kinase activity 9/573 140/18639 0.0642857142857143 2.09113687359761 0.0290759628831706 0.149233255279888 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 4/573 39/18639 0.102564102564103 3.33628674989932 0.0310902462778786 0.158616106758997 GO:0004602 glutathione peroxidase activity 3/573 23/18639 0.130434782608696 4.24288641019804 0.0324103274536842 0.163131594440337 GO:0099186 structural constituent of postsynapse 3/573 23/18639 0.130434782608696 4.24288641019804 0.0324103274536842 0.163131594440337 GO:0019207 kinase regulator activity 15/573 287/18639 0.0522648083623693 1.70011127934765 0.0325497312850438 0.163131594440337 GO:0001786 phosphatidylserine binding 5/573 59/18639 0.0847457627118644 2.75667761114562 0.034667075311665 0.172727182254611 GO:0004862 cAMP-dependent protein kinase inhibitor activity 2/573 10/18639 0.2 6.50575916230367 0.0360493890581418 0.173748130411992 GO:0032395 MHC class II receptor activity 2/573 10/18639 0.2 6.50575916230367 0.0360493890581418 0.173748130411992 GO:0050815 phosphoserine residue binding 2/573 10/18639 0.2 6.50575916230367 0.0360493890581418 0.173748130411992 GO:0004622 lysophospholipase activity 3/573 24/18639 0.125 4.06609947643979 0.0362179178679365 0.173748130411992 GO:0048027 mRNA 5'-UTR binding 3/573 24/18639 0.125 4.06609947643979 0.0362179178679365 0.173748130411992 GO:0050699 WW domain binding 3/573 24/18639 0.125 4.06609947643979 0.0362179178679365 0.173748130411992 GO:0001727 lipid kinase activity 4/573 41/18639 0.0975609756097561 3.17354105478228 0.0365034217649608 0.173748130411992 GO:0015175 neutral L-amino acid transmembrane transporter activity 4/573 41/18639 0.0975609756097561 3.17354105478228 0.0365034217649608 0.173748130411992 GO:0015101 organic cation transmembrane transporter activity 6/573 81/18639 0.0740740740740741 2.40954043048284 0.0384346888746913 0.181924194006872 GO:0008307 structural constituent of muscle 4/573 42/18639 0.0952380952380952 3.09798055347794 0.0394007027372692 0.185466291337864 GO:0120020 cholesterol transfer activity 3/573 25/18639 0.12 3.9034554973822 0.0402444635583729 0.18839715907546 GO:0005096 GTPase activator activity 14/573 271/18639 0.0516605166051661 1.680454396167 0.0412403690588255 0.189632233425495 GO:0015179 L-amino acid transmembrane transporter activity 5/573 62/18639 0.0806451612903226 2.62328998479986 0.0416260106104275 0.189632233425495 GO:0030165 PDZ domain binding 6/573 83/18639 0.072289156626506 2.35147921529048 0.0425073759008389 0.189632233425495 GO:0005114 type II transforming growth factor beta receptor binding 2/573 11/18639 0.181818181818182 5.91432651118515 0.0431791705217677 0.189632233425495 GO:0005536 D-glucose binding 2/573 11/18639 0.181818181818182 5.91432651118515 0.0431791705217677 0.189632233425495 GO:0016176 superoxide-generating NADPH oxidase activator activity 2/573 11/18639 0.181818181818182 5.91432651118515 0.0431791705217677 0.189632233425495 GO:0019206 nucleoside kinase activity 2/573 11/18639 0.181818181818182 5.91432651118515 0.0431791705217677 0.189632233425495 GO:0019215 intermediate filament binding 2/573 11/18639 0.181818181818182 5.91432651118515 0.0431791705217677 0.189632233425495 GO:0031731 CCR6 chemokine receptor binding 2/573 11/18639 0.181818181818182 5.91432651118515 0.0431791705217677 0.189632233425495 GO:0043522 leucine zipper domain binding 2/573 11/18639 0.181818181818182 5.91432651118515 0.0431791705217677 0.189632233425495 GO:0047676 arachidonate-CoA ligase activity 2/573 11/18639 0.181818181818182 5.91432651118515 0.0431791705217677 0.189632233425495 GO:0070697 activin receptor binding 2/573 11/18639 0.181818181818182 5.91432651118515 0.0431791705217677 0.189632233425495 GO:0031490 chromatin DNA binding 8/573 128/18639 0.0625 2.0330497382199 0.0440789440796846 0.19259107874816 GO:0052742 phosphatidylinositol kinase activity 3/573 26/18639 0.115384615384615 3.75332259363673 0.0444871204668145 0.193382788967989 GO:0019205 nucleobase-containing compound kinase activity 4/573 44/18639 0.0909090909090909 2.95716325559258 0.0455774308766831 0.197116604603726 GO:0042605 peptide antigen binding 4/573 45/18639 0.0888888888888889 2.89144851657941 0.0488566039957066 0.209013824324768 GO:0023026 MHC class II protein complex binding 3/573 27/18639 0.111111111111111 3.61431064572426 0.048942578846205 0.209013824324768 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 6/573 86/18639 0.0697674418604651 2.26945087057105 0.049107355246266 0.209013824324768 GO:0004859 phospholipase inhibitor activity 2/573 12/18639 0.166666666666667 5.42146596858639 0.0507815277408767 0.209013824324768 GO:0008603 cAMP-dependent protein kinase regulator activity 2/573 12/18639 0.166666666666667 5.42146596858639 0.0507815277408767 0.209013824324768 GO:0035014 phosphatidylinositol 3-kinase regulator activity 2/573 12/18639 0.166666666666667 5.42146596858639 0.0507815277408767 0.209013824324768 GO:0035197 siRNA binding 2/573 12/18639 0.166666666666667 5.42146596858639 0.0507815277408767 0.209013824324768 GO:0035497 cAMP response element binding 2/573 12/18639 0.166666666666667 5.42146596858639 0.0507815277408767 0.209013824324768 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity 2/573 12/18639 0.166666666666667 5.42146596858639 0.0507815277408767 0.209013824324768 GO:0070410 co-SMAD binding 2/573 12/18639 0.166666666666667 5.42146596858639 0.0507815277408767 0.209013824324768 GO:0097718 disordered domain specific binding 3/573 28/18639 0.107142857142857 3.48522812266268 0.0536071076710192 0.219582960267829 GO:0003712 transcription coregulator activity 22/573 495/18639 0.0444444444444444 1.4457242582897 0.0545058345791409 0.222196033786737 GO:0042578 phosphoric ester hydrolase activity 17/573 363/18639 0.046831955922865 1.5233871316689 0.0571935878724087 0.228836993324206 GO:1990841 promoter-specific chromatin binding 5/573 68/18639 0.0735294117647059 2.39182322143517 0.0579062486278368 0.228836993324206 GO:0003785 actin monomer binding 3/573 29/18639 0.103448275862069 3.36504784257086 0.0584765963662847 0.228836993324206 GO:0043236 laminin binding 3/573 29/18639 0.103448275862069 3.36504784257086 0.0584765963662847 0.228836993324206 GO:0005172 vascular endothelial growth factor receptor binding 2/573 13/18639 0.153846153846154 5.00443012484897 0.058820776453053 0.228836993324206 GO:0008035 high-density lipoprotein particle binding 2/573 13/18639 0.153846153846154 5.00443012484897 0.058820776453053 0.228836993324206 GO:0008253 5'-nucleotidase activity 2/573 13/18639 0.153846153846154 5.00443012484897 0.058820776453053 0.228836993324206 GO:0045159 myosin II binding 2/573 13/18639 0.153846153846154 5.00443012484897 0.058820776453053 0.228836993324206 GO:0061459 L-arginine transmembrane transporter activity 2/573 13/18639 0.153846153846154 5.00443012484897 0.058820776453053 0.228836993324206 GO:0070123 transforming growth factor beta receptor activity, type III 2/573 13/18639 0.153846153846154 5.00443012484897 0.058820776453053 0.228836993324206 GO:0001222 transcription corepressor binding 4/573 49/18639 0.0816326530612245 2.65541190298109 0.0632336283104313 0.243881522879218 GO:0033612 receptor serine/threonine kinase binding 3/573 30/18639 0.1 3.25287958115183 0.0635465939896554 0.243881522879218 GO:0098918 structural constituent of synapse 3/573 30/18639 0.1 3.25287958115183 0.0635465939896554 0.243881522879218 GO:0097110 scaffold protein binding 5/573 70/18639 0.0714285714285714 2.32348541510845 0.0640370657534881 0.244661793820502 GO:0070851 growth factor receptor binding 8/573 139/18639 0.0575539568345324 1.87216091001544 0.0652975837502382 0.248364023907156 GO:0034236 protein kinase A catalytic subunit binding 2/573 14/18639 0.142857142857143 4.6469708302169 0.0672629731202496 0.253575456187844 GO:0070742 C2H2 zinc finger domain binding 2/573 14/18639 0.142857142857143 4.6469708302169 0.0672629731202496 0.253575456187844 GO:0019902 phosphatase binding 10/573 190/18639 0.0526315789473684 1.71204188481675 0.0692782524710572 0.260022339671104 GO:0043425 bHLH transcription factor binding 3/573 32/18639 0.09375 3.04957460732984 0.0742688286993998 0.273926588969215 GO:0071813 lipoprotein particle binding 3/573 32/18639 0.09375 3.04957460732984 0.0742688286993998 0.273926588969215 GO:0071814 protein-lipid complex binding 3/573 32/18639 0.09375 3.04957460732984 0.0742688286993998 0.273926588969215 GO:0120015 sterol transfer activity 3/573 32/18639 0.09375 3.04957460732984 0.0742688286993998 0.273926588969215 GO:0004467 long-chain fatty acid-CoA ligase activity 2/573 15/18639 0.133333333333333 4.33717277486911 0.0760758419310455 0.27699409113355 GO:0008252 nucleotidase activity 2/573 15/18639 0.133333333333333 4.33717277486911 0.0760758419310455 0.27699409113355 GO:0034483 heparan sulfate sulfotransferase activity 2/573 15/18639 0.133333333333333 4.33717277486911 0.0760758419310455 0.27699409113355 GO:0019903 protein phosphatase binding 8/573 144/18639 0.0555555555555556 1.80715532286213 0.0767240003617157 0.27816531194971 GO:0019239 deaminase activity 3/573 33/18639 0.0909090909090909 2.95716325559258 0.0799107815725316 0.286067167646205 GO:0030296 protein tyrosine kinase activator activity 3/573 33/18639 0.0909090909090909 2.95716325559258 0.0799107815725316 0.286067167646205 GO:0071889 14-3-3 protein binding 3/573 33/18639 0.0909090909090909 2.95716325559258 0.0799107815725316 0.286067167646205 GO:0042277 peptide binding 12/573 249/18639 0.0481927710843374 1.56765281019365 0.0839457183834331 0.297601870278064 GO:0031625 ubiquitin protein ligase binding 14/573 302/18639 0.0463576158940397 1.50795742172601 0.0840677480882581 0.297601870278064 GO:0005159 insulin-like growth factor receptor binding 2/573 16/18639 0.125 4.06609947643979 0.0852287046336239 0.297601870278064 GO:0030275 LRR domain binding 2/573 16/18639 0.125 4.06609947643979 0.0852287046336239 0.297601870278064 GO:0034450 ubiquitin-ubiquitin ligase activity 2/573 16/18639 0.125 4.06609947643979 0.0852287046336239 0.297601870278064 GO:0106018 phosphatidylinositol-3,5-bisphosphate phosphatase activity 2/573 16/18639 0.125 4.06609947643979 0.0852287046336239 0.297601870278064 GO:0005154 epidermal growth factor receptor binding 3/573 35/18639 0.0857142857142857 2.78818249813014 0.0917290508279593 0.318992454307842 GO:0015171 amino acid transmembrane transporter activity 6/573 102/18639 0.0588235294117647 1.91345857714814 0.0944335409373195 0.324007774927078 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 2/573 17/18639 0.117647058823529 3.82691715429627 0.0946924130948855 0.324007774927078 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 2/573 17/18639 0.117647058823529 3.82691715429627 0.0946924130948855 0.324007774927078 GO:0038191 neuropilin binding 2/573 17/18639 0.117647058823529 3.82691715429627 0.0946924130948855 0.324007774927078 GO:0019887 protein kinase regulator activity 12/573 255/18639 0.0470588235294118 1.53076686171851 0.0958432799774193 0.32554058406847 GO:0015370 solute:sodium symporter activity 5/573 79/18639 0.0632911392405063 2.05878454503281 0.0959045617384812 0.32554058406847 GO:0004601 peroxidase activity 4/573 57/18639 0.0701754385964912 2.28272251308901 0.097806838485573 0.330680263451223 GO:0003714 transcription corepressor activity 10/573 204/18639 0.0490196078431373 1.59454881429011 0.0993578329601078 0.334596338664079 GO:0061980 regulatory RNA binding 4/573 58/18639 0.0689655172413793 2.24336522838057 0.102642921717712 0.344298304344453 GO:0023023 MHC protein complex binding 3/573 37/18639 0.0810810810810811 2.63746993066365 0.104221432745216 0.344892520856938 GO:0042805 actinin binding 3/573 37/18639 0.0810810810810811 2.63746993066365 0.104221432745216 0.344892520856938 GO:0015172 acidic amino acid transmembrane transporter activity 2/573 18/18639 0.111111111111111 3.61431064572426 0.104439284484848 0.344892520856938 GO:1901611 phosphatidylglycerol binding 2/573 18/18639 0.111111111111111 3.61431064572426 0.104439284484848 0.344892520856938 GO:0016298 lipase activity 7/573 130/18639 0.0538461538461538 1.75155054369714 0.106300507060143 0.34968352129437 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 4/573 59/18639 0.0677966101694915 2.2053420889165 0.107586619638152 0.352553076660407 GO:0008013 beta-catenin binding 6/573 106/18639 0.0566037735849057 1.84125259310481 0.108391440878152 0.353829531142472 GO:0005109 frizzled binding 3/573 38/18639 0.0789473684210526 2.56806282722513 0.110705547300826 0.36000429885612 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 20/573 484/18639 0.0413223140495868 1.34416511617844 0.111749904673269 0.362018702591729 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 4/573 60/18639 0.0666666666666667 2.16858638743456 0.112635650519532 0.363505963040306 GO:0030506 ankyrin binding 2/573 19/18639 0.105263157894737 3.42408376963351 0.114443038989087 0.366561914356024 GO:0050145 nucleoside monophosphate kinase activity 2/573 19/18639 0.105263157894737 3.42408376963351 0.114443038989087 0.366561914356024 GO:0051117 ATPase binding 5/573 84/18639 0.0595238095238095 1.93623784592371 0.116505630257141 0.371770775202563 GO:0016776 phosphotransferase activity, phosphate group as acceptor 3/573 39/18639 0.0769230769230769 2.50221506242449 0.117340155719405 0.373036614451242 GO:0004620 phospholipase activity 6/573 109/18639 0.055045871559633 1.79057591623037 0.119516389332209 0.37854261602618 GO:0016757 glycosyltransferase activity 12/573 267/18639 0.0449438202247191 1.46196835107948 0.12254993826051 0.386459847883493 GO:0044389 ubiquitin-like protein ligase binding 14/573 322/18639 0.0434782608695652 1.41429547006601 0.122923261474679 0.386459847883493 GO:0001216 DNA-binding transcription activator activity 20/573 491/18639 0.0407331975560081 1.32500186604963 0.123620058855962 0.387221654945881 GO:0008083 growth factor activity 8/573 162/18639 0.0493827160493827 1.60636028698856 0.127100075662145 0.396663972396144 GO:0001664 G protein-coupled receptor binding 13/573 297/18639 0.0437710437710438 1.42381934528531 0.128740029929881 0.400315713504593 GO:0015174 basic amino acid transmembrane transporter activity 2/573 21/18639 0.0952380952380952 3.09798055347794 0.135122736384774 0.41561217111851 GO:0019200 carbohydrate kinase activity 2/573 21/18639 0.0952380952380952 3.09798055347794 0.135122736384774 0.41561217111851 GO:0051428 peptide hormone receptor binding 2/573 21/18639 0.0952380952380952 3.09798055347794 0.135122736384774 0.41561217111851 GO:0035198 miRNA binding 3/573 42/18639 0.0714285714285714 2.32348541510845 0.138084986025101 0.423195712566136 GO:0120013 lipid transfer activity 4/573 65/18639 0.0615384615384615 2.00177204993959 0.139375493014628 0.425619785119939 GO:0005243 gap junction channel activity 2/573 22/18639 0.0909090909090909 2.95716325559258 0.145752607678016 0.441926056020177 GO:0008093 cytoskeletal anchor activity 2/573 22/18639 0.0909090909090909 2.95716325559258 0.145752607678016 0.441926056020177 GO:0072341 modified amino acid binding 5/573 91/18639 0.0549450549450549 1.78729647316035 0.148514737585651 0.44870410079069 GO:0019955 cytokine binding 7/573 144/18639 0.0486111111111111 1.58126090750436 0.155817965369869 0.466357126553002 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 2/573 23/18639 0.0869565217391304 2.82859094013203 0.156547110556524 0.466357126553002 GO:0017134 fibroblast growth factor binding 2/573 23/18639 0.0869565217391304 2.82859094013203 0.156547110556524 0.466357126553002 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 2/573 23/18639 0.0869565217391304 2.82859094013203 0.156547110556524 0.466357126553002 GO:0051213 dioxygenase activity 5/573 93/18639 0.0537634408602151 1.74885998986658 0.15828243142289 0.469883733701403 GO:0008194 UDP-glycosyltransferase activity 7/573 145/18639 0.0482758620689655 1.5703556598664 0.159707199001527 0.472467130379518 GO:0003713 transcription coactivator activity 11/573 256/18639 0.04296875 1.39772169502618 0.166763848193468 0.488692401091663 GO:0030291 protein serine/threonine kinase inhibitor activity 3/573 46/18639 0.0652173913043478 2.12144320509902 0.167473958372982 0.488692401091663 GO:0030552 cAMP binding 2/573 24/18639 0.0833333333333333 2.71073298429319 0.167486128073668 0.488692401091663 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 2/573 24/18639 0.0833333333333333 2.71073298429319 0.167486128073668 0.488692401091663 GO:0004709 MAP kinase kinase kinase activity 2/573 25/18639 0.08 2.60230366492147 0.178550620640216 0.512205820826477 GO:0015645 fatty acid ligase activity 2/573 25/18639 0.08 2.60230366492147 0.178550620640216 0.512205820826477 GO:0042974 nuclear retinoic acid receptor binding 2/573 25/18639 0.08 2.60230366492147 0.178550620640216 0.512205820826477 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 2/573 25/18639 0.08 2.60230366492147 0.178550620640216 0.512205820826477 GO:0120515 fatty acid-CoA ligase activity 2/573 25/18639 0.08 2.60230366492147 0.178550620640216 0.512205820826477 GO:0042379 chemokine receptor binding 4/573 72/18639 0.0555555555555556 1.80715532286213 0.180514596757504 0.516102135695952 GO:0140693 molecular condensate scaffold activity 3/573 48/18639 0.0625 2.0330497382199 0.182797575316182 0.520881385181897 GO:0004435 phosphatidylinositol phospholipase C activity 2/573 26/18639 0.0769230769230769 2.50221506242449 0.189722578987999 0.532416822547292 GO:0008198 ferrous iron binding 2/573 26/18639 0.0769230769230769 2.50221506242449 0.189722578987999 0.532416822547292 GO:0019865 immunoglobulin binding 2/573 26/18639 0.0769230769230769 2.50221506242449 0.189722578987999 0.532416822547292 GO:0030247 polysaccharide binding 2/573 26/18639 0.0769230769230769 2.50221506242449 0.189722578987999 0.532416822547292 GO:0016763 pentosyltransferase activity 3/573 49/18639 0.0612244897959184 1.99155892723582 0.190595224033948 0.532416822547292 GO:0035254 glutamate receptor binding 3/573 49/18639 0.0612244897959184 1.99155892723582 0.190595224033948 0.532416822547292 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 8/573 181/18639 0.0441988950276243 1.43773683144832 0.194771929310981 0.54230615612077 GO:0048020 CCR chemokine receptor binding 3/573 50/18639 0.06 1.9517277486911 0.198475424856644 0.54709010257968 GO:0001671 ATPase activator activity 2/573 27/18639 0.0740740740740741 2.40954043048284 0.200984978999343 0.54709010257968 GO:0004683 calcium/calmodulin-dependent protein kinase activity 2/573 27/18639 0.0740740740740741 2.40954043048284 0.200984978999343 0.54709010257968 GO:0008266 poly(U) RNA binding 2/573 27/18639 0.0740740740740741 2.40954043048284 0.200984978999343 0.54709010257968 GO:0016405 CoA-ligase activity 2/573 27/18639 0.0740740740740741 2.40954043048284 0.200984978999343 0.54709010257968 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity 2/573 27/18639 0.0740740740740741 2.40954043048284 0.200984978999343 0.54709010257968 GO:0035255 ionotropic glutamate receptor binding 2/573 27/18639 0.0740740740740741 2.40954043048284 0.200984978999343 0.54709010257968 GO:0016798 hydrolase activity, acting on glycosyl bonds 6/573 130/18639 0.0461538461538462 1.50132903745469 0.211267015575057 0.565306628309724 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 6/573 130/18639 0.0461538461538462 1.50132903745469 0.211267015575057 0.565306628309724 GO:0005242 inward rectifier potassium channel activity 2/573 28/18639 0.0714285714285714 2.32348541510845 0.212321738332291 0.565306628309724 GO:0050698 proteoglycan sulfotransferase activity 2/573 28/18639 0.0714285714285714 2.32348541510845 0.212321738332291 0.565306628309724 GO:0051393 alpha-actinin binding 2/573 28/18639 0.0714285714285714 2.32348541510845 0.212321738332291 0.565306628309724 GO:0051959 dynein light intermediate chain binding 2/573 28/18639 0.0714285714285714 2.32348541510845 0.212321738332291 0.565306628309724 GO:0141052 histone H3 demethylase activity 2/573 28/18639 0.0714285714285714 2.32348541510845 0.212321738332291 0.565306628309724 GO:0005080 protein kinase C binding 3/573 52/18639 0.0576923076923077 1.87666129681836 0.214459921882465 0.569220727239441 GO:0031406 carboxylic acid binding 8/573 187/18639 0.0427807486631016 1.39160623792592 0.218763866734698 0.578841038689325 GO:0051018 protein kinase A binding 3/573 53/18639 0.0566037735849057 1.84125259310481 0.222552655475535 0.587042917848779 GO:0004629 phospholipase C activity 2/573 29/18639 0.0689655172413793 2.24336522838057 0.223717674774217 0.588294626258126 GO:0043177 organic acid binding 8/573 189/18639 0.0423280423280423 1.37688024599019 0.226998730886621 0.595085903739697 GO:0015485 cholesterol binding 3/573 54/18639 0.0555555555555556 1.80715532286213 0.230704828295763 0.60110248840364 GO:0140463 chromatin-protein adaptor activity 3/573 54/18639 0.0555555555555556 1.80715532286213 0.230704828295763 0.60110248840364 GO:0019888 protein phosphatase regulator activity 5/573 107/18639 0.0467289719626168 1.52003718745413 0.233035922897887 0.605302154841456 GO:0008187 poly-pyrimidine tract binding 2/573 30/18639 0.0666666666666667 2.16858638743456 0.235158466258829 0.605302154841456 GO:0031210 phosphatidylcholine binding 2/573 30/18639 0.0666666666666667 2.16858638743456 0.235158466258829 0.605302154841456 GO:0032452 histone demethylase activity 2/573 30/18639 0.0666666666666667 2.16858638743456 0.235158466258829 0.605302154841456 GO:0030971 receptor tyrosine kinase binding 4/573 81/18639 0.0493827160493827 1.60636028698856 0.238323480561291 0.61126753699505 GO:0140313 molecular sequestering activity 3/573 55/18639 0.0545454545454545 1.77429795335554 0.23891090354384 0.61126753699505 GO:0016922 nuclear receptor binding 6/573 137/18639 0.0437956204379562 1.42461879466504 0.246216310625685 0.619367542292905 GO:0008327 methyl-CpG binding 2/573 31/18639 0.0645161290322581 2.09863198783989 0.246630612483927 0.619367542292905 GO:0016878 acid-thiol ligase activity 2/573 31/18639 0.0645161290322581 2.09863198783989 0.246630612483927 0.619367542292905 GO:0017147 Wnt-protein binding 2/573 31/18639 0.0645161290322581 2.09863198783989 0.246630612483927 0.619367542292905 GO:0047499 calcium-independent phospholipase A2 activity 2/573 31/18639 0.0645161290322581 2.09863198783989 0.246630612483927 0.619367542292905 GO:0140457 protein demethylase activity 2/573 31/18639 0.0645161290322581 2.09863198783989 0.246630612483927 0.619367542292905 GO:0170055 lipid transmembrane transporter activity 3/573 56/18639 0.0535714285714286 1.74261406133134 0.247165451149751 0.619367542292905 GO:0004222 metalloendopeptidase activity 5/573 110/18639 0.0454545454545455 1.47858162779629 0.250228337044295 0.625203938890731 GO:0047498 calcium-dependent phospholipase A2 activity 2/573 32/18639 0.0625 2.0330497382199 0.258121398069562 0.626508935682894 GO:0016758 hexosyltransferase activity 8/573 197/18639 0.0406091370558376 1.3209663273713 0.260984433104906 0.626508935682894 GO:0004955 prostaglandin receptor activity 1/573 10/18639 0.1 3.25287958115183 0.268253408089413 0.626508935682894 GO:0005522 profilin binding 1/573 10/18639 0.1 3.25287958115183 0.268253408089413 0.626508935682894 GO:0005528 FK506 binding 1/573 10/18639 0.1 3.25287958115183 0.268253408089413 0.626508935682894 GO:0008401 retinoic acid 4-hydroxylase activity 1/573 10/18639 0.1 3.25287958115183 0.268253408089413 0.626508935682894 GO:0015187 glycine transmembrane transporter activity 1/573 10/18639 0.1 3.25287958115183 0.268253408089413 0.626508935682894 GO:0015643 toxic substance binding 1/573 10/18639 0.1 3.25287958115183 0.268253408089413 0.626508935682894 GO:0015924 mannosyl-oligosaccharide mannosidase activity 1/573 10/18639 0.1 3.25287958115183 0.268253408089413 0.626508935682894 GO:0016303 1-phosphatidylinositol-3-kinase activity 1/573 10/18639 0.1 3.25287958115183 0.268253408089413 0.626508935682894 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines 1/573 10/18639 0.1 3.25287958115183 0.268253408089413 0.626508935682894 GO:0016868 intramolecular phosphotransferase activity 1/573 10/18639 0.1 3.25287958115183 0.268253408089413 0.626508935682894 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity 1/573 10/18639 0.1 3.25287958115183 0.268253408089413 0.626508935682894 GO:0019911 structural constituent of myelin sheath 1/573 10/18639 0.1 3.25287958115183 0.268253408089413 0.626508935682894 GO:0031956 medium-chain fatty acid-CoA ligase activity 1/573 10/18639 0.1 3.25287958115183 0.268253408089413 0.626508935682894 GO:0031957 very long-chain fatty acid-CoA ligase activity 1/573 10/18639 0.1 3.25287958115183 0.268253408089413 0.626508935682894 GO:0035256 G protein-coupled glutamate receptor binding 1/573 10/18639 0.1 3.25287958115183 0.268253408089413 0.626508935682894 GO:0035374 chondroitin sulfate binding 1/573 10/18639 0.1 3.25287958115183 0.268253408089413 0.626508935682894 GO:0042975 peroxisome proliferator activated receptor binding 1/573 10/18639 0.1 3.25287958115183 0.268253408089413 0.626508935682894 GO:0043121 neurotrophin binding 1/573 10/18639 0.1 3.25287958115183 0.268253408089413 0.626508935682894 GO:0051880 G-quadruplex DNA binding 1/573 10/18639 0.1 3.25287958115183 0.268253408089413 0.626508935682894 GO:0070097 delta-catenin binding 1/573 10/18639 0.1 3.25287958115183 0.268253408089413 0.626508935682894 GO:0140999 histone H3K4 trimethyltransferase activity 1/573 10/18639 0.1 3.25287958115183 0.268253408089413 0.626508935682894 GO:0140311 protein sequestering activity 2/573 33/18639 0.0606060606060606 1.97144217039505 0.269618857198402 0.626508935682894 GO:0070888 E-box binding 3/573 59/18639 0.0508474576271186 1.65400656668737 0.272167310473285 0.626508935682894 GO:0017124 SH3 domain binding 5/573 115/18639 0.0434782608695652 1.41429547006601 0.279541937427832 0.626508935682894 GO:0019825 oxygen binding 2/573 34/18639 0.0588235294117647 1.91345857714814 0.281111739682254 0.626508935682894 GO:0051427 hormone receptor binding 2/573 34/18639 0.0588235294117647 1.91345857714814 0.281111739682254 0.626508935682894 GO:0052866 phosphatidylinositol phosphate phosphatase activity 2/573 34/18639 0.0588235294117647 1.91345857714814 0.281111739682254 0.626508935682894 GO:0090482 vitamin transmembrane transporter activity 2/573 34/18639 0.0588235294117647 1.91345857714814 0.281111739682254 0.626508935682894 GO:0015294 solute:monoatomic cation symporter activity 5/573 116/18639 0.0431034482758621 1.40210326773786 0.285487551835097 0.626508935682894 GO:0015026 coreceptor activity 3/573 61/18639 0.0491803278688525 1.59977684318943 0.288983165202363 0.626508935682894 GO:0000014 single-stranded DNA endodeoxyribonuclease activity 1/573 11/18639 0.0909090909090909 2.95716325559258 0.290760831846178 0.626508935682894 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding 1/573 11/18639 0.0909090909090909 2.95716325559258 0.290760831846178 0.626508935682894 GO:0002162 dystroglycan binding 1/573 11/18639 0.0909090909090909 2.95716325559258 0.290760831846178 0.626508935682894 GO:0004143 ATP-dependent diacylglycerol kinase activity 1/573 11/18639 0.0909090909090909 2.95716325559258 0.290760831846178 0.626508935682894 GO:0004954 prostanoid receptor activity 1/573 11/18639 0.0909090909090909 2.95716325559258 0.290760831846178 0.626508935682894 GO:0008199 ferric iron binding 1/573 11/18639 0.0909090909090909 2.95716325559258 0.290760831846178 0.626508935682894 GO:0008432 JUN kinase binding 1/573 11/18639 0.0909090909090909 2.95716325559258 0.290760831846178 0.626508935682894 GO:0008526 phosphatidylinositol transfer activity 1/573 11/18639 0.0909090909090909 2.95716325559258 0.290760831846178 0.626508935682894 GO:0015173 aromatic amino acid transmembrane transporter activity 1/573 11/18639 0.0909090909090909 2.95716325559258 0.290760831846178 0.626508935682894 GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor 1/573 11/18639 0.0909090909090909 2.95716325559258 0.290760831846178 0.626508935682894 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 1/573 11/18639 0.0909090909090909 2.95716325559258 0.290760831846178 0.626508935682894 GO:0032050 clathrin heavy chain binding 1/573 11/18639 0.0909090909090909 2.95716325559258 0.290760831846178 0.626508935682894 GO:0032794 GTPase activating protein binding 1/573 11/18639 0.0909090909090909 2.95716325559258 0.290760831846178 0.626508935682894 GO:0034594 phosphatidylinositol trisphosphate phosphatase activity 1/573 11/18639 0.0909090909090909 2.95716325559258 0.290760831846178 0.626508935682894 GO:0034713 type I transforming growth factor beta receptor binding 1/573 11/18639 0.0909090909090909 2.95716325559258 0.290760831846178 0.626508935682894 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding 1/573 11/18639 0.0909090909090909 2.95716325559258 0.290760831846178 0.626508935682894 GO:0042608 T cell receptor binding 1/573 11/18639 0.0909090909090909 2.95716325559258 0.290760831846178 0.626508935682894 GO:0048407 platelet-derived growth factor binding 1/573 11/18639 0.0909090909090909 2.95716325559258 0.290760831846178 0.626508935682894 GO:0140031 phosphorylation-dependent protein binding 1/573 11/18639 0.0909090909090909 2.95716325559258 0.290760831846178 0.626508935682894 GO:0140537 transcription regulator activator activity 1/573 11/18639 0.0909090909090909 2.95716325559258 0.290760831846178 0.626508935682894 GO:0019208 phosphatase regulator activity 5/573 117/18639 0.0427350427350427 1.39011947912471 0.291456678430201 0.626508935682894 GO:0004623 phospholipase A2 activity 2/573 35/18639 0.0571428571428571 1.85878833208676 0.292589478400696 0.626508935682894 GO:0061631 ubiquitin conjugating enzyme activity 2/573 35/18639 0.0571428571428571 1.85878833208676 0.292589478400696 0.626508935682894 GO:0005125 cytokine activity 9/573 234/18639 0.0384615384615385 1.25110753121224 0.294053364528199 0.626508935682894 GO:0019210 kinase inhibitor activity 4/573 90/18639 0.0444444444444444 1.4457242582897 0.299702466662514 0.626508935682894 GO:0005507 copper ion binding 3/573 63/18639 0.0476190476190476 1.54899027673897 0.30587245550532 0.626508935682894 GO:0005319 lipid transporter activity 7/573 178/18639 0.0393258426966292 1.27922230719454 0.307838755080204 0.626508935682894 GO:0004000 adenosine deaminase activity 1/573 12/18639 0.0833333333333333 2.71073298429319 0.312577132219387 0.626508935682894 GO:0004126 cytidine deaminase activity 1/573 12/18639 0.0833333333333333 2.71073298429319 0.312577132219387 0.626508935682894 GO:0005025 transforming growth factor beta receptor activity, type I 1/573 12/18639 0.0833333333333333 2.71073298429319 0.312577132219387 0.626508935682894 GO:0005026 transforming growth factor beta receptor activity, type II 1/573 12/18639 0.0833333333333333 2.71073298429319 0.312577132219387 0.626508935682894 GO:0005165 neurotrophin receptor binding 1/573 12/18639 0.0833333333333333 2.71073298429319 0.312577132219387 0.626508935682894 GO:0005436 sodium:phosphate symporter activity 1/573 12/18639 0.0833333333333333 2.71073298429319 0.312577132219387 0.626508935682894 GO:0015132 prostaglandin transmembrane transporter activity 1/573 12/18639 0.0833333333333333 2.71073298429319 0.312577132219387 0.626508935682894 GO:0015269 calcium-activated potassium channel activity 1/573 12/18639 0.0833333333333333 2.71073298429319 0.312577132219387 0.626508935682894 GO:0016208 AMP binding 1/573 12/18639 0.0833333333333333 2.71073298429319 0.312577132219387 0.626508935682894 GO:0016361 activin receptor activity, type I 1/573 12/18639 0.0833333333333333 2.71073298429319 0.312577132219387 0.626508935682894 GO:0016362 activin receptor activity, type II 1/573 12/18639 0.0833333333333333 2.71073298429319 0.312577132219387 0.626508935682894 GO:0016840 carbon-nitrogen lyase activity 1/573 12/18639 0.0833333333333333 2.71073298429319 0.312577132219387 0.626508935682894 GO:0017002 activin receptor activity 1/573 12/18639 0.0833333333333333 2.71073298429319 0.312577132219387 0.626508935682894 GO:0017166 vinculin binding 1/573 12/18639 0.0833333333333333 2.71073298429319 0.312577132219387 0.626508935682894 GO:0031543 peptidyl-proline dioxygenase activity 1/573 12/18639 0.0833333333333333 2.71073298429319 0.312577132219387 0.626508935682894 GO:0035259 nuclear glucocorticoid receptor binding 1/573 12/18639 0.0833333333333333 2.71073298429319 0.312577132219387 0.626508935682894 GO:0042301 phosphate ion binding 1/573 12/18639 0.0833333333333333 2.71073298429319 0.312577132219387 0.626508935682894 GO:0043047 single-stranded telomeric DNA binding 1/573 12/18639 0.0833333333333333 2.71073298429319 0.312577132219387 0.626508935682894 GO:0097677 STAT family protein binding 1/573 12/18639 0.0833333333333333 2.71073298429319 0.312577132219387 0.626508935682894 GO:0140807 NAD+-protein-glutamate ADP-ribosyltransferase activity 1/573 12/18639 0.0833333333333333 2.71073298429319 0.312577132219387 0.626508935682894 GO:0140822 NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity 1/573 12/18639 0.0833333333333333 2.71073298429319 0.312577132219387 0.626508935682894 GO:0140844 NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity 1/573 12/18639 0.0833333333333333 2.71073298429319 0.312577132219387 0.626508935682894 GO:0140867 NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity 1/573 12/18639 0.0833333333333333 2.71073298429319 0.312577132219387 0.626508935682894 GO:1990459 transferrin receptor binding 1/573 12/18639 0.0833333333333333 2.71073298429319 0.312577132219387 0.626508935682894 GO:0043178 alcohol binding 4/573 92/18639 0.0434782608695652 1.41429547006601 0.313621246471145 0.626508935682894 GO:0019842 vitamin binding 6/573 150/18639 0.04 1.30115183246073 0.314821150818035 0.626508935682894 GO:0022829 wide pore channel activity 2/573 37/18639 0.0540540540540541 1.7583132871091 0.315460485220612 0.626508935682894 GO:0030280 structural constituent of skin epidermis 2/573 37/18639 0.0540540540540541 1.7583132871091 0.315460485220612 0.626508935682894 GO:0030551 cyclic nucleotide binding 2/573 37/18639 0.0540540540540541 1.7583132871091 0.315460485220612 0.626508935682894 GO:0019843 rRNA binding 3/573 65/18639 0.0461538461538462 1.50132903745469 0.322798927168691 0.639397946161363 GO:0000146 microfilament motor activity 2/573 38/18639 0.0526315789473684 1.71204188481675 0.326835759549489 0.639397946161363 GO:0043531 ADP binding 2/573 38/18639 0.0526315789473684 1.71204188481675 0.326835759549489 0.639397946161363 GO:0016410 N-acyltransferase activity 4/573 94/18639 0.0425531914893617 1.38420407708589 0.327595667165622 0.639397946161363 GO:0003774 cytoskeletal motor activity 6/573 153/18639 0.0392156862745098 1.27563905143209 0.331108850823331 0.639397946161363 GO:0017154 semaphorin receptor activity 1/573 13/18639 0.0769230769230769 2.50221506242449 0.333723495199915 0.639397946161363 GO:0019855 calcium channel inhibitor activity 1/573 13/18639 0.0769230769230769 2.50221506242449 0.333723495199915 0.639397946161363 GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity 1/573 13/18639 0.0769230769230769 2.50221506242449 0.333723495199915 0.639397946161363 GO:0071714 icosanoid transmembrane transporter activity 1/573 13/18639 0.0769230769230769 2.50221506242449 0.333723495199915 0.639397946161363 GO:0071837 HMG box domain binding 1/573 13/18639 0.0769230769230769 2.50221506242449 0.333723495199915 0.639397946161363 GO:0089720 caspase binding 1/573 13/18639 0.0769230769230769 2.50221506242449 0.333723495199915 0.639397946161363 GO:0140666 annealing activity 1/573 13/18639 0.0769230769230769 2.50221506242449 0.333723495199915 0.639397946161363 GO:0140806 NAD+-protein-aspartate ADP-ribosyltransferase activity 1/573 13/18639 0.0769230769230769 2.50221506242449 0.333723495199915 0.639397946161363 GO:0005506 iron ion binding 6/573 154/18639 0.038961038961039 1.26735568096825 0.336562269973139 0.639397946161363 GO:0000217 DNA secondary structure binding 2/573 39/18639 0.0512820512820513 1.66814337494966 0.338159846243007 0.639397946161363 GO:0004896 cytokine receptor activity 4/573 96/18639 0.0416666666666667 1.3553664921466 0.341605750835476 0.639397946161363 GO:0008017 microtubule binding 10/573 276/18639 0.036231884057971 1.17857955838835 0.343448674641661 0.639397946161363 GO:0140375 immune receptor activity 6/573 156/18639 0.0384615384615385 1.25110753121224 0.347498268316136 0.639397946161363 GO:0003777 microtubule motor activity 3/573 68/18639 0.0441176470588235 1.4350939328611 0.348184059768414 0.639397946161363 GO:0032934 sterol binding 3/573 68/18639 0.0441176470588235 1.4350939328611 0.348184059768414 0.639397946161363 GO:0032451 demethylase activity 2/573 40/18639 0.05 1.62643979057592 0.349425149583273 0.639397946161363 GO:0050997 quaternary ammonium group binding 2/573 40/18639 0.05 1.62643979057592 0.349425149583273 0.639397946161363 GO:0033218 amide binding 9/573 247/18639 0.0364372469635627 1.1852597664116 0.349571250046319 0.639397946161363 GO:0001217 DNA-binding transcription repressor activity 10/573 278/18639 0.0359712230215827 1.17010056875965 0.351618058538254 0.639397946161363 GO:0005313 L-glutamate transmembrane transporter activity 1/573 14/18639 0.0714285714285714 2.32348541510845 0.354220458436811 0.639397946161363 GO:0008191 metalloendopeptidase inhibitor activity 1/573 14/18639 0.0714285714285714 2.32348541510845 0.354220458436811 0.639397946161363 GO:0008195 phosphatidate phosphatase activity 1/573 14/18639 0.0714285714285714 2.32348541510845 0.354220458436811 0.639397946161363 GO:0008474 palmitoyl-(protein) hydrolase activity 1/573 14/18639 0.0714285714285714 2.32348541510845 0.354220458436811 0.639397946161363 GO:0008494 translation activator activity 1/573 14/18639 0.0714285714285714 2.32348541510845 0.354220458436811 0.639397946161363 GO:0016530 metallochaperone activity 1/573 14/18639 0.0714285714285714 2.32348541510845 0.354220458436811 0.639397946161363 GO:0019992 diacylglycerol binding 1/573 14/18639 0.0714285714285714 2.32348541510845 0.354220458436811 0.639397946161363 GO:0032036 myosin heavy chain binding 1/573 14/18639 0.0714285714285714 2.32348541510845 0.354220458436811 0.639397946161363 GO:0034595 phosphatidylinositol phosphate 5-phosphatase activity 1/573 14/18639 0.0714285714285714 2.32348541510845 0.354220458436811 0.639397946161363 GO:0042043 neurexin family protein binding 1/573 14/18639 0.0714285714285714 2.32348541510845 0.354220458436811 0.639397946161363 GO:0042813 Wnt receptor activity 1/573 14/18639 0.0714285714285714 2.32348541510845 0.354220458436811 0.639397946161363 GO:0043176 amine binding 1/573 14/18639 0.0714285714285714 2.32348541510845 0.354220458436811 0.639397946161363 GO:0052816 long-chain fatty acyl-CoA hydrolase activity 1/573 14/18639 0.0714285714285714 2.32348541510845 0.354220458436811 0.639397946161363 GO:0098599 palmitoyl hydrolase activity 1/573 14/18639 0.0714285714285714 2.32348541510845 0.354220458436811 0.639397946161363 GO:0098821 BMP receptor activity 1/573 14/18639 0.0714285714285714 2.32348541510845 0.354220458436811 0.639397946161363 GO:0098847 sequence-specific single stranded DNA binding 1/573 14/18639 0.0714285714285714 2.32348541510845 0.354220458436811 0.639397946161363 GO:1901474 azole transmembrane transporter activity 1/573 14/18639 0.0714285714285714 2.32348541510845 0.354220458436811 0.639397946161363 GO:1901612 cardiolipin binding 1/573 14/18639 0.0714285714285714 2.32348541510845 0.354220458436811 0.639397946161363 GO:1990825 sequence-specific mRNA binding 1/573 14/18639 0.0714285714285714 2.32348541510845 0.354220458436811 0.639397946161363 GO:0002039 p53 binding 3/573 69/18639 0.0434782608695652 1.41429547006601 0.356628594386617 0.641444986676716 GO:0046943 carboxylic acid transmembrane transporter activity 7/573 188/18639 0.0372340425531915 1.21117856745015 0.357550484404185 0.641444986676716 GO:0016877 ligase activity, forming carbon-sulfur bonds 2/573 41/18639 0.0487804878048781 1.58677052739114 0.360624587579985 0.641444986676716 GO:0017080 sodium channel regulator activity 2/573 41/18639 0.0487804878048781 1.58677052739114 0.360624587579985 0.641444986676716 GO:0042169 SH2 domain binding 2/573 41/18639 0.0487804878048781 1.58677052739114 0.360624587579985 0.641444986676716 GO:0061650 ubiquitin-like protein conjugating enzyme activity 2/573 41/18639 0.0487804878048781 1.58677052739114 0.360624587579985 0.641444986676716 GO:0140318 protein transporter activity 2/573 41/18639 0.0487804878048781 1.58677052739114 0.360624587579985 0.641444986676716 GO:0005342 organic acid transmembrane transporter activity 7/573 189/18639 0.037037037037037 1.20477021524142 0.362571705693323 0.643564777605648 GO:0016782 transferase activity, transferring sulphur-containing groups 3/573 70/18639 0.0428571428571429 1.39409124906507 0.365058265092706 0.646631272056103 GO:0004559 alpha-mannosidase activity 1/573 15/18639 0.0666666666666667 2.16858638743456 0.374087931044366 0.649130177698167 GO:0004865 protein serine/threonine phosphatase inhibitor activity 1/573 15/18639 0.0666666666666667 2.16858638743456 0.374087931044366 0.649130177698167 GO:0004953 icosanoid receptor activity 1/573 15/18639 0.0666666666666667 2.16858638743456 0.374087931044366 0.649130177698167 GO:0005523 tropomyosin binding 1/573 15/18639 0.0666666666666667 2.16858638743456 0.374087931044366 0.649130177698167 GO:0015929 hexosaminidase activity 1/573 15/18639 0.0666666666666667 2.16858638743456 0.374087931044366 0.649130177698167 GO:0033130 acetylcholine receptor binding 1/573 15/18639 0.0666666666666667 2.16858638743456 0.374087931044366 0.649130177698167 GO:0051371 muscle alpha-actinin binding 1/573 15/18639 0.0666666666666667 2.16858638743456 0.374087931044366 0.649130177698167 GO:0061578 K63-linked deubiquitinase activity 1/573 15/18639 0.0666666666666667 2.16858638743456 0.374087931044366 0.649130177698167 GO:0120283 protein serine/threonine kinase binding 1/573 15/18639 0.0666666666666667 2.16858638743456 0.374087931044366 0.649130177698167 GO:0140161 monocarboxylate:sodium symporter activity 1/573 15/18639 0.0666666666666667 2.16858638743456 0.374087931044366 0.649130177698167 GO:0005245 voltage-gated calcium channel activity 2/573 43/18639 0.0465116279069767 1.51296724704736 0.382799963348378 0.659110032104801 GO:0008200 ion channel inhibitor activity 2/573 43/18639 0.0465116279069767 1.51296724704736 0.382799963348378 0.659110032104801 GO:0008375 acetylglucosaminyltransferase activity 2/573 43/18639 0.0465116279069767 1.51296724704736 0.382799963348378 0.659110032104801 GO:0043539 protein serine/threonine kinase activator activity 3/573 73/18639 0.0410958904109589 1.33679982787062 0.390222971019641 0.659110032104801 GO:0015081 sodium ion transmembrane transporter activity 6/573 164/18639 0.0365853658536585 1.19007789554335 0.391462089731977 0.659110032104801 GO:0004198 calcium-dependent cysteine-type endopeptidase activity 1/573 16/18639 0.0625 2.0330497382199 0.393345212805083 0.659110032104801 GO:0004708 MAP kinase kinase activity 1/573 16/18639 0.0625 2.0330497382199 0.393345212805083 0.659110032104801 GO:0005324 long-chain fatty acid transmembrane transporter activity 1/573 16/18639 0.0625 2.0330497382199 0.393345212805083 0.659110032104801 GO:0015378 sodium:chloride symporter activity 1/573 16/18639 0.0625 2.0330497382199 0.393345212805083 0.659110032104801 GO:0015923 mannosidase activity 1/573 16/18639 0.0625 2.0330497382199 0.393345212805083 0.659110032104801 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 1/573 16/18639 0.0625 2.0330497382199 0.393345212805083 0.659110032104801 GO:0016722 oxidoreductase activity, acting on metal ions 1/573 16/18639 0.0625 2.0330497382199 0.393345212805083 0.659110032104801 GO:0019841 retinol binding 1/573 16/18639 0.0625 2.0330497382199 0.393345212805083 0.659110032104801 GO:0022841 potassium ion leak channel activity 1/573 16/18639 0.0625 2.0330497382199 0.393345212805083 0.659110032104801 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 1/573 16/18639 0.0625 2.0330497382199 0.393345212805083 0.659110032104801 GO:0016248 channel inhibitor activity 2/573 44/18639 0.0454545454545455 1.47858162779629 0.393764091949934 0.659110032104801 GO:0016790 thiolester hydrolase activity 2/573 44/18639 0.0454545454545455 1.47858162779629 0.393764091949934 0.659110032104801 GO:0030020 extracellular matrix structural constituent conferring tensile strength 2/573 44/18639 0.0454545454545455 1.47858162779629 0.393764091949934 0.659110032104801 GO:0004715 non-membrane spanning protein tyrosine kinase activity 2/573 45/18639 0.0444444444444444 1.4457242582897 0.404638693114583 0.66863501503714 GO:0008009 chemokine activity 2/573 45/18639 0.0444444444444444 1.4457242582897 0.404638693114583 0.66863501503714 GO:0141110 transporter inhibitor activity 2/573 45/18639 0.0444444444444444 1.4457242582897 0.404638693114583 0.66863501503714 GO:0016779 nucleotidyltransferase activity 5/573 136/18639 0.0367647058823529 1.19591161071759 0.407106842151244 0.66863501503714 GO:0016874 ligase activity 6/573 167/18639 0.0359281437125748 1.16869925071323 0.407959710049172 0.66863501503714 GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity 1/573 17/18639 0.0588235294117647 1.91345857714814 0.41201101278697 0.66863501503714 GO:0004550 nucleoside diphosphate kinase activity 1/573 17/18639 0.0588235294117647 1.91345857714814 0.41201101278697 0.66863501503714 GO:0005092 GDP-dissociation inhibitor activity 1/573 17/18639 0.0588235294117647 1.91345857714814 0.41201101278697 0.66863501503714 GO:0008429 phosphatidylethanolamine binding 1/573 17/18639 0.0588235294117647 1.91345857714814 0.41201101278697 0.66863501503714 GO:0008569 minus-end-directed microtubule motor activity 1/573 17/18639 0.0588235294117647 1.91345857714814 0.41201101278697 0.66863501503714 GO:0015347 sodium-independent organic anion transmembrane transporter activity 1/573 17/18639 0.0588235294117647 1.91345857714814 0.41201101278697 0.66863501503714 GO:0030169 low-density lipoprotein particle binding 1/573 17/18639 0.0588235294117647 1.91345857714814 0.41201101278697 0.66863501503714 GO:0030548 acetylcholine receptor regulator activity 1/573 17/18639 0.0588235294117647 1.91345857714814 0.41201101278697 0.66863501503714 GO:0036041 long-chain fatty acid binding 1/573 17/18639 0.0588235294117647 1.91345857714814 0.41201101278697 0.66863501503714 GO:0046965 nuclear retinoid X receptor binding 1/573 17/18639 0.0588235294117647 1.91345857714814 0.41201101278697 0.66863501503714 GO:1990226 histone methyltransferase binding 1/573 17/18639 0.0588235294117647 1.91345857714814 0.41201101278697 0.66863501503714 GO:0005496 steroid binding 4/573 108/18639 0.037037037037037 1.20477021524142 0.425387964973907 0.681130398176239 GO:0005504 fatty acid binding 2/573 47/18639 0.0425531914893617 1.38420407708589 0.426100261260131 0.681130398176239 GO:0140938 histone H3 methyltransferase activity 2/573 47/18639 0.0425531914893617 1.38420407708589 0.426100261260131 0.681130398176239 GO:0000400 four-way junction DNA binding 1/573 18/18639 0.0555555555555556 1.80715532286213 0.430103467392977 0.681130398176239 GO:0004706 JUN kinase kinase kinase activity 1/573 18/18639 0.0555555555555556 1.80715532286213 0.430103467392977 0.681130398176239 GO:0015373 monoatomic anion:sodium symporter activity 1/573 18/18639 0.0555555555555556 1.80715532286213 0.430103467392977 0.681130398176239 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 1/573 18/18639 0.0555555555555556 1.80715532286213 0.430103467392977 0.681130398176239 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 1/573 18/18639 0.0555555555555556 1.80715532286213 0.430103467392977 0.681130398176239 GO:0017075 syntaxin-1 binding 1/573 18/18639 0.0555555555555556 1.80715532286213 0.430103467392977 0.681130398176239 GO:0031690 adrenergic receptor binding 1/573 18/18639 0.0555555555555556 1.80715532286213 0.430103467392977 0.681130398176239 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 1/573 18/18639 0.0555555555555556 1.80715532286213 0.430103467392977 0.681130398176239 GO:0052744 phosphatidylinositol monophosphate phosphatase activity 1/573 18/18639 0.0555555555555556 1.80715532286213 0.430103467392977 0.681130398176239 GO:0099602 neurotransmitter receptor regulator activity 1/573 18/18639 0.0555555555555556 1.80715532286213 0.430103467392977 0.681130398176239 GO:0140297 DNA-binding transcription factor binding 16/573 488/18639 0.0327868852459016 1.06651789545962 0.432074278629042 0.68298197660843 GO:0016879 ligase activity, forming carbon-nitrogen bonds 2/573 48/18639 0.0416666666666667 1.3553664921466 0.436678638909868 0.688428546022745 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 9/573 268/18639 0.0335820895522388 1.0923849339689 0.441477701430954 0.688428546022745 GO:0060590 ATPase regulator activity 2/573 49/18639 0.0408163265306122 1.32770595149054 0.447150273585439 0.688428546022745 GO:0008301 DNA binding, bending 1/573 19/18639 0.0526315789473684 1.71204188481675 0.44764015785986 0.688428546022745 GO:0008381 mechanosensitive monoatomic ion channel activity 1/573 19/18639 0.0526315789473684 1.71204188481675 0.44764015785986 0.688428546022745 GO:0008574 plus-end-directed microtubule motor activity 1/573 19/18639 0.0526315789473684 1.71204188481675 0.44764015785986 0.688428546022745 GO:0015245 fatty acid transmembrane transporter activity 1/573 19/18639 0.0526315789473684 1.71204188481675 0.44764015785986 0.688428546022745 GO:0015355 secondary active monocarboxylate transmembrane transporter activity 1/573 19/18639 0.0526315789473684 1.71204188481675 0.44764015785986 0.688428546022745 GO:0016918 retinal binding 1/573 19/18639 0.0526315789473684 1.71204188481675 0.44764015785986 0.688428546022745 GO:0022840 leak channel activity 1/573 19/18639 0.0526315789473684 1.71204188481675 0.44764015785986 0.688428546022745 GO:0022842 narrow pore channel activity 1/573 19/18639 0.0526315789473684 1.71204188481675 0.44764015785986 0.688428546022745 GO:0031420 alkali metal ion binding 1/573 19/18639 0.0526315789473684 1.71204188481675 0.44764015785986 0.688428546022745 GO:0042577 lipid phosphatase activity 1/573 19/18639 0.0526315789473684 1.71204188481675 0.44764015785986 0.688428546022745 GO:0042800 histone H3K4 methyltransferase activity 1/573 19/18639 0.0526315789473684 1.71204188481675 0.44764015785986 0.688428546022745 GO:0097001 ceramide binding 1/573 19/18639 0.0526315789473684 1.71204188481675 0.44764015785986 0.688428546022745 GO:0022843 voltage-gated monoatomic cation channel activity 5/573 143/18639 0.034965034965035 1.13737048292022 0.449523903042333 0.690079937643365 GO:0005516 calmodulin binding 7/573 207/18639 0.0338164251207729 1.10000758782912 0.453087381289178 0.694299368450322 GO:0004252 serine-type endopeptidase activity 6/573 176/18639 0.0340909090909091 1.10893622084722 0.457115497627719 0.699214369800389 GO:0046982 protein heterodimerization activity 12/573 369/18639 0.032520325203252 1.05784701826076 0.462711362074245 0.705653626371137 GO:0015095 magnesium ion transmembrane transporter activity 1/573 20/18639 0.05 1.62643979057592 0.464638127223249 0.705653626371137 GO:0016004 phospholipase activator activity 1/573 20/18639 0.05 1.62643979057592 0.464638127223249 0.705653626371137 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 1/573 20/18639 0.05 1.62643979057592 0.464638127223249 0.705653626371137 GO:0015293 symporter activity 5/573 146/18639 0.0342465753424658 1.11399985655885 0.467473074813434 0.707871059538418 GO:0016597 amino acid binding 2/573 51/18639 0.0392156862745098 1.27563905143209 0.467759866807664 0.707871059538418 GO:0001540 amyloid-beta binding 3/573 83/18639 0.036144578313253 1.17573960764524 0.471832593835624 0.712768386432539 GO:0004175 endopeptidase activity 13/573 405/18639 0.0320987654320988 1.04413418654256 0.476741104035416 0.712885287032916 GO:0004860 protein kinase inhibitor activity 3/573 84/18639 0.0357142857142857 1.16174270755423 0.479734196144841 0.712885287032916 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 1/573 21/18639 0.0476190476190476 1.54899027673897 0.481113896765172 0.712885287032916 GO:0001846 opsonin binding 1/573 21/18639 0.0476190476190476 1.54899027673897 0.481113896765172 0.712885287032916 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 1/573 21/18639 0.0476190476190476 1.54899027673897 0.481113896765172 0.712885287032916 GO:0008373 sialyltransferase activity 1/573 21/18639 0.0476190476190476 1.54899027673897 0.481113896765172 0.712885287032916 GO:0035613 RNA stem-loop binding 1/573 21/18639 0.0476190476190476 1.54899027673897 0.481113896765172 0.712885287032916 GO:0036122 BMP binding 1/573 21/18639 0.0476190476190476 1.54899027673897 0.481113896765172 0.712885287032916 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 1/573 21/18639 0.0476190476190476 1.54899027673897 0.481113896765172 0.712885287032916 GO:0051010 microtubule plus-end binding 1/573 21/18639 0.0476190476190476 1.54899027673897 0.481113896765172 0.712885287032916 GO:0061891 calcium ion sensor activity 1/573 21/18639 0.0476190476190476 1.54899027673897 0.481113896765172 0.712885287032916 GO:0004864 protein phosphatase inhibitor activity 2/573 53/18639 0.0377358490566038 1.22750172873654 0.487905166923462 0.720442291540363 GO:0008146 sulfotransferase activity 2/573 53/18639 0.0377358490566038 1.22750172873654 0.487905166923462 0.720442291540363 GO:0008970 phospholipase A1 activity 1/573 22/18639 0.0454545454545455 1.47858162779629 0.497083481959799 0.725197134639981 GO:0015377 chloride:monoatomic cation symporter activity 1/573 22/18639 0.0454545454545455 1.47858162779629 0.497083481959799 0.725197134639981 GO:0016780 phosphotransferase activity, for other substituted phosphate groups 1/573 22/18639 0.0454545454545455 1.47858162779629 0.497083481959799 0.725197134639981 GO:0030021 extracellular matrix structural constituent conferring compression resistance 1/573 22/18639 0.0454545454545455 1.47858162779629 0.497083481959799 0.725197134639981 GO:0033691 sialic acid binding 1/573 22/18639 0.0454545454545455 1.47858162779629 0.497083481959799 0.725197134639981 GO:0050321 tau-protein kinase activity 1/573 22/18639 0.0454545454545455 1.47858162779629 0.497083481959799 0.725197134639981 GO:0140784 metal ion sensor activity 1/573 22/18639 0.0454545454545455 1.47858162779629 0.497083481959799 0.725197134639981 GO:0008374 O-acyltransferase activity 2/573 55/18639 0.0363636363636364 1.18286530223703 0.507566792700141 0.739225482701743 GO:0042171 lysophosphatidic acid acyltransferase activity 1/573 23/18639 0.0434782608695652 1.41429547006601 0.512562407932675 0.741431530659829 GO:0043274 phospholipase binding 1/573 23/18639 0.0434782608695652 1.41429547006601 0.512562407932675 0.741431530659829 GO:0071617 lysophospholipid acyltransferase activity 1/573 23/18639 0.0434782608695652 1.41429547006601 0.512562407932675 0.741431530659829 GO:0140103 catalytic activity, acting on a glycoprotein 1/573 23/18639 0.0434782608695652 1.41429547006601 0.512562407932675 0.741431530659829 GO:0019212 phosphatase inhibitor activity 2/573 56/18639 0.0357142857142857 1.16174270755423 0.517211286831636 0.746888163356871 GO:0061630 ubiquitin protein ligase activity 11/573 353/18639 0.0311614730878187 1.01364519525978 0.524895418818991 0.752907868056847 GO:0004806 triacylglycerol lipase activity 1/573 24/18639 0.0416666666666667 1.3553664921466 0.527565724448284 0.752907868056847 GO:0005315 phosphate transmembrane transporter activity 1/573 24/18639 0.0416666666666667 1.3553664921466 0.527565724448284 0.752907868056847 GO:0005540 hyaluronic acid binding 1/573 24/18639 0.0416666666666667 1.3553664921466 0.527565724448284 0.752907868056847 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 1/573 24/18639 0.0416666666666667 1.3553664921466 0.527565724448284 0.752907868056847 GO:0060229 lipase activator activity 1/573 24/18639 0.0416666666666667 1.3553664921466 0.527565724448284 0.752907868056847 GO:0070840 dynein complex binding 1/573 24/18639 0.0416666666666667 1.3553664921466 0.527565724448284 0.752907868056847 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 3/573 91/18639 0.032967032967033 1.07237788389621 0.533382421352912 0.759936158850637 GO:0001848 complement binding 1/573 25/18639 0.04 1.30115183246073 0.542108020440287 0.760916035280271 GO:0008139 nuclear localization sequence binding 1/573 25/18639 0.04 1.30115183246073 0.542108020440287 0.760916035280271 GO:0008483 transaminase activity 1/573 25/18639 0.04 1.30115183246073 0.542108020440287 0.760916035280271 GO:0015296 monoatomic anion:monoatomic cation symporter activity 1/573 25/18639 0.04 1.30115183246073 0.542108020440287 0.760916035280271 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 1/573 25/18639 0.04 1.30115183246073 0.542108020440287 0.760916035280271 GO:0017056 structural constituent of nuclear pore 1/573 25/18639 0.04 1.30115183246073 0.542108020440287 0.760916035280271 GO:0019706 protein-cysteine S-palmitoyltransferase activity 1/573 25/18639 0.04 1.30115183246073 0.542108020440287 0.760916035280271 GO:0019707 protein-cysteine S-acyltransferase activity 1/573 25/18639 0.04 1.30115183246073 0.542108020440287 0.760916035280271 GO:0047617 fatty acyl-CoA hydrolase activity 1/573 25/18639 0.04 1.30115183246073 0.542108020440287 0.760916035280271 GO:0004879 nuclear receptor activity 2/573 59/18639 0.0338983050847458 1.10267104445825 0.545381269542392 0.762996455911524 GO:0031593 polyubiquitin modification-dependent protein binding 2/573 59/18639 0.0338983050847458 1.10267104445825 0.545381269542392 0.762996455911524 GO:0008236 serine-type peptidase activity 6/573 194/18639 0.0309278350515464 1.00604523128407 0.551749540670836 0.764331176225514 GO:0098531 ligand-modulated transcription factor activity 2/573 60/18639 0.0333333333333333 1.08429319371728 0.554512909401484 0.764331176225514 GO:0005112 Notch binding 1/573 26/18639 0.0384615384615385 1.25110753121224 0.556203438098379 0.764331176225514 GO:0005227 calcium-activated cation channel activity 1/573 26/18639 0.0384615384615385 1.25110753121224 0.556203438098379 0.764331176225514 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 1/573 26/18639 0.0384615384615385 1.25110753121224 0.556203438098379 0.764331176225514 GO:0008157 protein phosphatase 1 binding 1/573 26/18639 0.0384615384615385 1.25110753121224 0.556203438098379 0.764331176225514 GO:0016289 acyl-CoA hydrolase activity 1/573 26/18639 0.0384615384615385 1.25110753121224 0.556203438098379 0.764331176225514 GO:0034237 protein kinase A regulatory subunit binding 1/573 26/18639 0.0384615384615385 1.25110753121224 0.556203438098379 0.764331176225514 GO:0050681 nuclear androgen receptor binding 1/573 26/18639 0.0384615384615385 1.25110753121224 0.556203438098379 0.764331176225514 GO:0050750 low-density lipoprotein particle receptor binding 1/573 26/18639 0.0384615384615385 1.25110753121224 0.556203438098379 0.764331176225514 GO:0120014 phospholipid transfer activity 1/573 26/18639 0.0384615384615385 1.25110753121224 0.556203438098379 0.764331176225514 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 7/573 229/18639 0.0305676855895196 0.994330002972176 0.559568670429687 0.767717402908363 GO:0000287 magnesium ion binding 7/573 230/18639 0.0304347826086957 0.99000682904621 0.564200788436583 0.77282808962696 GO:0004364 glutathione transferase activity 1/573 27/18639 0.037037037037037 1.20477021524142 0.569865686525265 0.773129880445104 GO:0005044 scavenger receptor activity 1/573 27/18639 0.037037037037037 1.20477021524142 0.569865686525265 0.773129880445104 GO:0008320 protein transmembrane transporter activity 1/573 27/18639 0.037037037037037 1.20477021524142 0.569865686525265 0.773129880445104 GO:0008395 steroid hydroxylase activity 1/573 27/18639 0.037037037037037 1.20477021524142 0.569865686525265 0.773129880445104 GO:0015252 proton channel activity 1/573 27/18639 0.037037037037037 1.20477021524142 0.569865686525265 0.773129880445104 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors 1/573 27/18639 0.037037037037037 1.20477021524142 0.569865686525265 0.773129880445104 GO:0017171 serine hydrolase activity 6/573 198/18639 0.0303030303030303 0.985721085197525 0.571774839744508 0.774486746362991 GO:0031072 heat shock protein binding 4/573 131/18639 0.0305343511450382 0.993245673634147 0.575634406396012 0.778477006745083 GO:0016866 intramolecular transferase activity 1/573 28/18639 0.0357142857142857 1.16174270755423 0.583108054976856 0.782030824221117 GO:0019789 SUMO transferase activity 1/573 28/18639 0.0357142857142857 1.16174270755423 0.583108054976856 0.782030824221117 GO:0046625 sphingolipid binding 1/573 28/18639 0.0357142857142857 1.16174270755423 0.583108054976856 0.782030824221117 GO:0051019 mitogen-activated protein kinase binding 1/573 28/18639 0.0357142857142857 1.16174270755423 0.583108054976856 0.782030824221117 GO:0051537 2 iron, 2 sulfur cluster binding 1/573 28/18639 0.0357142857142857 1.16174270755423 0.583108054976856 0.782030824221117 GO:0005249 voltage-gated potassium channel activity 3/573 98/18639 0.0306122448979592 0.995779463617908 0.583769488503087 0.782030824221117 GO:0008514 organic anion transmembrane transporter activity 8/573 269/18639 0.0297397769516729 0.967399131941065 0.587897846641524 0.786324906339998 GO:0061659 ubiquitin-like protein ligase activity 11/573 372/18639 0.0295698924731183 0.961872994426617 0.595215385613015 0.792640605706933 GO:0016417 S-acyltransferase activity 1/573 29/18639 0.0344827586206897 1.12168261419029 0.595943425698379 0.792640605706933 GO:0106222 lncRNA binding 1/573 29/18639 0.0344827586206897 1.12168261419029 0.595943425698379 0.792640605706933 GO:0043130 ubiquitin binding 3/573 100/18639 0.03 0.97586387434555 0.597515370365369 0.792640605706933 GO:0038024 cargo receptor activity 2/573 65/18639 0.0307692307692308 1.00088602496979 0.598201771677885 0.792640605706933 GO:0160215 deacylase activity 2/573 65/18639 0.0307692307692308 1.00088602496979 0.598201771677885 0.792640605706933 GO:0001965 G-protein alpha-subunit binding 1/573 30/18639 0.0333333333333333 1.08429319371728 0.608384286368708 0.798680141735192 GO:0008106 alcohol dehydrogenase (NADP+) activity 1/573 30/18639 0.0333333333333333 1.08429319371728 0.608384286368708 0.798680141735192 GO:0016769 transferase activity, transferring nitrogenous groups 1/573 30/18639 0.0333333333333333 1.08429319371728 0.608384286368708 0.798680141735192 GO:0022839 monoatomic ion-gated channel activity 1/573 30/18639 0.0333333333333333 1.08429319371728 0.608384286368708 0.798680141735192 GO:0031624 ubiquitin conjugating enzyme binding 1/573 30/18639 0.0333333333333333 1.08429319371728 0.608384286368708 0.798680141735192 GO:0051721 protein phosphatase 2A binding 1/573 30/18639 0.0333333333333333 1.08429319371728 0.608384286368708 0.798680141735192 GO:0042054 histone methyltransferase activity 2/573 67/18639 0.0298507462686567 0.971008830194577 0.614753232995124 0.805799622325917 GO:0005244 voltage-gated monoatomic ion channel activity 5/573 173/18639 0.0289017341040462 0.940138607269316 0.617852324852813 0.807377577875149 GO:0140030 modification-dependent protein binding 5/573 173/18639 0.0289017341040462 0.940138607269316 0.617852324852813 0.807377577875149 GO:0005184 neuropeptide hormone activity 1/573 31/18639 0.032258064516129 1.04931599391995 0.620442742164868 0.808283205389094 GO:0016411 acylglycerol O-acyltransferase activity 1/573 31/18639 0.032258064516129 1.04931599391995 0.620442742164868 0.808283205389094 GO:0140767 enzyme-substrate adaptor activity 4/573 139/18639 0.0287769784172662 0.936080455007722 0.62245882847962 0.809671636434559 GO:0004842 ubiquitin-protein transferase activity 13/573 449/18639 0.0289532293986637 0.941813687193181 0.626977467037571 0.813557718118491 GO:0022832 voltage-gated channel activity 5/573 175/18639 0.0285714285714286 0.929394166043381 0.627965427447719 0.813557718118491 GO:0016279 protein-lysine N-methyltransferase activity 2/573 69/18639 0.0289855072463768 0.942863646710676 0.630777429784272 0.813557718118491 GO:0022884 macromolecule transmembrane transporter activity 1/573 32/18639 0.03125 1.01652486910995 0.632130527458264 0.813557718118491 GO:0031369 translation initiation factor binding 1/573 32/18639 0.03125 1.01652486910995 0.632130527458264 0.813557718118491 GO:0070717 poly-purine tract binding 1/573 32/18639 0.03125 1.01652486910995 0.632130527458264 0.813557718118491 GO:0160041 neuropeptide activity 1/573 32/18639 0.03125 1.01652486910995 0.632130527458264 0.813557718118491 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 10/573 349/18639 0.0286532951289398 0.932057186576456 0.634295575827029 0.815112866673648 GO:0004497 monooxygenase activity 3/573 106/18639 0.0283018867924528 0.920626296552405 0.636939133936612 0.81520829807333 GO:0043021 ribonucleoprotein complex binding 5/573 177/18639 0.0282485875706215 0.91889253704854 0.637915568178018 0.81520829807333 GO:0008028 monocarboxylic acid transmembrane transporter activity 2/573 70/18639 0.0285714285714286 0.929394166043381 0.638592699334024 0.81520829807333 GO:0016278 lysine N-methyltransferase activity 2/573 70/18639 0.0285714285714286 0.929394166043381 0.638592699334024 0.81520829807333 GO:0020037 heme binding 4/573 142/18639 0.028169014084507 0.916304107366713 0.639153923841531 0.81520829807333 GO:0140416 transcription regulator inhibitor activity 1/573 33/18639 0.0303030303030303 0.985721085197525 0.643459017153886 0.819472470276697 GO:0015020 glucuronosyltransferase activity 1/573 34/18639 0.0294117647058824 0.956729288574068 0.654439237683329 0.828502571331643 GO:0015035 protein-disulfide reductase activity 1/573 34/18639 0.0294117647058824 0.956729288574068 0.654439237683329 0.828502571331643 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 1/573 34/18639 0.0294117647058824 0.956729288574068 0.654439237683329 0.828502571331643 GO:0030332 cyclin binding 1/573 34/18639 0.0294117647058824 0.956729288574068 0.654439237683329 0.828502571331643 GO:0003678 DNA helicase activity 2/573 74/18639 0.027027027027027 0.879156643554549 0.668555059308993 0.840463431395078 GO:0031491 nucleosome binding 2/573 74/18639 0.027027027027027 0.879156643554549 0.668555059308993 0.840463431395078 GO:0035064 methylated histone binding 2/573 74/18639 0.027027027027027 0.879156643554549 0.668555059308993 0.840463431395078 GO:0008237 metallopeptidase activity 5/573 184/18639 0.0271739130434783 0.883934668791259 0.671422970486555 0.840463431395078 GO:0004033 aldo-keto reductase (NADPH) activity 1/573 36/18639 0.0277777777777778 0.903577661431065 0.6753972982223 0.840463431395078 GO:0016409 palmitoyltransferase activity 1/573 36/18639 0.0277777777777778 0.903577661431065 0.6753972982223 0.840463431395078 GO:0044390 ubiquitin-like protein conjugating enzyme binding 1/573 36/18639 0.0277777777777778 0.903577661431065 0.6753972982223 0.840463431395078 GO:0045505 dynein intermediate chain binding 1/573 36/18639 0.0277777777777778 0.903577661431065 0.6753972982223 0.840463431395078 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 1/573 36/18639 0.0277777777777778 0.903577661431065 0.6753972982223 0.840463431395078 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 1/573 36/18639 0.0277777777777778 0.903577661431065 0.6753972982223 0.840463431395078 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 1/573 36/18639 0.0277777777777778 0.903577661431065 0.6753972982223 0.840463431395078 GO:0003725 double-stranded RNA binding 2/573 75/18639 0.0266666666666667 0.867434554973822 0.675724707166231 0.840463431395078 GO:0017022 myosin binding 2/573 76/18639 0.0263157894736842 0.856020942408377 0.682767734750968 0.846751251830895 GO:0140034 methylation-dependent protein binding 2/573 76/18639 0.0263157894736842 0.856020942408377 0.682767734750968 0.846751251830895 GO:0019213 deacetylase activity 1/573 37/18639 0.027027027027027 0.879156643554549 0.685395543027902 0.848774713168274 GO:0046906 tetrapyrrole binding 4/573 152/18639 0.0263157894736842 0.856020942408377 0.691244456296656 0.854775437974965 GO:0005501 retinoid binding 1/573 38/18639 0.0263157894736842 0.856020942408377 0.695086347986778 0.85579995445771 GO:0019840 isoprenoid binding 1/573 38/18639 0.0263157894736842 0.856020942408377 0.695086347986778 0.85579995445771 GO:0042162 telomeric DNA binding 1/573 38/18639 0.0263157894736842 0.856020942408377 0.695086347986778 0.85579995445771 GO:0033293 monocarboxylic acid binding 2/573 79/18639 0.0253164556962025 0.823513818013122 0.703147327835192 0.856930503819567 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 1/573 39/18639 0.0256410256410256 0.834071687474829 0.704479150664246 0.856930503819567 GO:0004386 helicase activity 4/573 155/18639 0.0258064516129032 0.839452795135957 0.705786887293645 0.856930503819567 GO:0000049 tRNA binding 2/573 80/18639 0.025 0.813219895287958 0.709694381077734 0.856930503819567 GO:0048306 calcium-dependent protein binding 2/573 80/18639 0.025 0.813219895287958 0.709694381077734 0.856930503819567 GO:0015036 disulfide oxidoreductase activity 1/573 40/18639 0.025 0.813219895287958 0.713583099409912 0.856930503819567 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 1/573 40/18639 0.025 0.813219895287958 0.713583099409912 0.856930503819567 GO:0061791 GTPase motor activity 1/573 40/18639 0.025 0.813219895287958 0.713583099409912 0.856930503819567 GO:0071855 neuropeptide receptor binding 1/573 40/18639 0.025 0.813219895287958 0.713583099409912 0.856930503819567 GO:0071949 FAD binding 1/573 40/18639 0.025 0.813219895287958 0.713583099409912 0.856930503819567 GO:1990606 membrane scission GTPase motor activity 1/573 40/18639 0.025 0.813219895287958 0.713583099409912 0.856930503819567 GO:0019787 ubiquitin-like protein transferase activity 13/573 479/18639 0.0271398747390397 0.882827443736406 0.715842169500132 0.856930503819567 GO:0033192 calmodulin-dependent protein phosphatase activity 2/573 81/18639 0.0246913580246914 0.80318014349428 0.7161203271356 0.856930503819567 GO:0140791 histone H2AXS140 phosphatase activity 2/573 81/18639 0.0246913580246914 0.80318014349428 0.7161203271356 0.856930503819567 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 2/573 81/18639 0.0246913580246914 0.80318014349428 0.7161203271356 0.856930503819567 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 2/573 81/18639 0.0246913580246914 0.80318014349428 0.7161203271356 0.856930503819567 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 2/573 81/18639 0.0246913580246914 0.80318014349428 0.7161203271356 0.856930503819567 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 2/573 81/18639 0.0246913580246914 0.80318014349428 0.7161203271356 0.856930503819567 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 2/573 81/18639 0.0246913580246914 0.80318014349428 0.7161203271356 0.856930503819567 GO:1990439 MAP kinase serine/threonine phosphatase activity 2/573 81/18639 0.0246913580246914 0.80318014349428 0.7161203271356 0.856930503819567 GO:0032182 ubiquitin-like protein binding 3/573 120/18639 0.025 0.813219895287958 0.718107730267946 0.857820398384834 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 2/573 82/18639 0.024390243902439 0.793385263695569 0.72242640997802 0.857820398384834 GO:0033549 MAP kinase phosphatase activity 2/573 82/18639 0.024390243902439 0.793385263695569 0.72242640997802 0.857820398384834 GO:0015108 chloride transmembrane transporter activity 3/573 121/18639 0.0247933884297521 0.806499069707066 0.7233279360064 0.857820398384834 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 3/573 122/18639 0.0245901639344262 0.799888421594713 0.728472493318271 0.857820398384834 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 2/573 83/18639 0.0240963855421687 0.783826405096827 0.728613911611166 0.857820398384834 GO:0005254 chloride channel activity 2/573 83/18639 0.0240963855421687 0.783826405096827 0.728613911611166 0.857820398384834 GO:0099106 ion channel regulator activity 4/573 160/18639 0.025 0.813219895287958 0.728908606733215 0.857820398384834 GO:0004520 DNA endonuclease activity 1/573 42/18639 0.0238095238095238 0.774495138369484 0.730959635243415 0.857820398384834 GO:0016859 cis-trans isomerase activity 1/573 42/18639 0.0238095238095238 0.774495138369484 0.730959635243415 0.857820398384834 GO:0019894 kinesin binding 1/573 42/18639 0.0238095238095238 0.774495138369484 0.730959635243415 0.857820398384834 GO:0031492 nucleosomal DNA binding 1/573 42/18639 0.0238095238095238 0.774495138369484 0.730959635243415 0.857820398384834 GO:0042056 chemoattractant activity 1/573 42/18639 0.0238095238095238 0.774495138369484 0.730959635243415 0.857820398384834 GO:0051879 Hsp90 protein binding 1/573 42/18639 0.0238095238095238 0.774495138369484 0.730959635243415 0.857820398384834 GO:0017018 myosin phosphatase activity 2/573 84/18639 0.0238095238095238 0.774495138369484 0.734684148573759 0.859822657396762 GO:0180051 translation factor activity 2/573 84/18639 0.0238095238095238 0.774495138369484 0.734684148573759 0.859822657396762 GO:0005267 potassium channel activity 3/573 124/18639 0.0241935483870968 0.786986995439959 0.738536245941297 0.862794899804465 GO:0004712 protein serine/threonine/tyrosine kinase activity 1/573 43/18639 0.0232558139534884 0.756483623523682 0.739249151240915 0.862794899804465 GO:0050660 flavin adenine dinucleotide binding 2/573 86/18639 0.0232558139534884 0.756483623523682 0.746478247522844 0.868602594478825 GO:0001046 core promoter sequence-specific DNA binding 1/573 44/18639 0.0227272727272727 0.739290813898144 0.747283687503496 0.868602594478825 GO:0030547 signaling receptor inhibitor activity 1/573 44/18639 0.0227272727272727 0.739290813898144 0.747283687503496 0.868602594478825 GO:0015631 tubulin binding 10/573 385/18639 0.025974025974026 0.844903787312164 0.74967078490774 0.870137339682927 GO:0015103 inorganic anion transmembrane transporter activity 4/573 165/18639 0.0242424242424242 0.78857686815802 0.75064664867013 0.870137339682927 GO:0008081 phosphoric diester hydrolase activity 2/573 87/18639 0.0229885057471264 0.747788409460191 0.752204886168228 0.870758917140394 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 3/573 128/18639 0.0234375 0.762393651832461 0.757774792088999 0.873697531943688 GO:0004197 cysteine-type endopeptidase activity 2/573 88/18639 0.0227272727272727 0.739290813898144 0.757819807636603 0.873697531943688 GO:0016651 oxidoreductase activity, acting on NAD(P)H 2/573 88/18639 0.0227272727272727 0.739290813898144 0.757819807636603 0.873697531943688 GO:0016755 aminoacyltransferase activity 13/573 496/18639 0.0262096774193548 0.852569245059956 0.759867017797328 0.874129617320494 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 1/573 46/18639 0.0217391304347826 0.707147735033007 0.762618899637597 0.874129617320494 GO:0030276 clathrin binding 1/573 46/18639 0.0217391304347826 0.707147735033007 0.762618899637597 0.874129617320494 GO:0016247 channel regulator activity 4/573 168/18639 0.0238095238095238 0.774495138369484 0.763034385031295 0.874129617320494 GO:0003727 single-stranded RNA binding 2/573 89/18639 0.0224719101123595 0.730984175539738 0.763324454561558 0.874129617320494 GO:0061749 forked DNA-dependent helicase activity 1/573 47/18639 0.0212765957446809 0.692102038542943 0.76993452221102 0.879335406064061 GO:1990518 single-stranded 3'-5' DNA helicase activity 1/573 47/18639 0.0212765957446809 0.692102038542943 0.76993452221102 0.879335406064061 GO:0141108 transporter regulator activity 4/573 170/18639 0.0235294117647059 0.765383430859255 0.771023841982515 0.879400687241101 GO:0009378 four-way junction helicase activity 1/573 48/18639 0.0208333333333333 0.677683246073298 0.777025072919555 0.882700482836615 GO:0036121 double-stranded DNA helicase activity 1/573 48/18639 0.0208333333333333 0.677683246073298 0.777025072919555 0.882700482836615 GO:0043138 3'-5' DNA helicase activity 1/573 48/18639 0.0208333333333333 0.677683246073298 0.777025072919555 0.882700482836615 GO:0052689 carboxylic ester hydrolase activity 2/573 92/18639 0.0217391304347826 0.707147735033007 0.779191415190736 0.883982803918119 GO:0015291 secondary active transmembrane transporter activity 7/573 287/18639 0.024390243902439 0.793385263695569 0.782963612248206 0.887081113876957 GO:0003823 antigen binding 4/573 174/18639 0.0229885057471264 0.747788409460191 0.786367290575838 0.889754225193378 GO:0099094 ligand-gated monoatomic cation channel activity 3/573 136/18639 0.0220588235294118 0.717546966430551 0.792813722099099 0.894672255711834 GO:0008276 protein methyltransferase activity 2/573 95/18639 0.0210526315789474 0.684816753926701 0.794119208766366 0.894672255711834 GO:0003743 translation initiation factor activity 1/573 51/18639 0.0196078431372549 0.637819525716045 0.797014368644698 0.894672255711834 GO:0005048 signal sequence binding 1/573 51/18639 0.0196078431372549 0.637819525716045 0.797014368644698 0.894672255711834 GO:0005272 sodium channel activity 1/573 51/18639 0.0196078431372549 0.637819525716045 0.797014368644698 0.894672255711834 GO:0016830 carbon-carbon lyase activity 1/573 51/18639 0.0196078431372549 0.637819525716045 0.797014368644698 0.894672255711834 GO:0016407 acetyltransferase activity 2/573 96/18639 0.0208333333333333 0.677683246073298 0.798893469268558 0.895601626074752 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 1/573 52/18639 0.0192307692307692 0.625553765606122 0.803271672645482 0.899326498152367 GO:0008170 N-methyltransferase activity 2/573 98/18639 0.0204081632653061 0.663852975745272 0.808148587711834 0.90359920830772 GO:0005246 calcium channel regulator activity 1/573 53/18639 0.0188679245283019 0.61375086436827 0.809336413140137 0.90374131585242 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 1/573 54/18639 0.0185185185185185 0.60238510762071 0.815214506074103 0.907925175392335 GO:0051287 NAD binding 1/573 54/18639 0.0185185185185185 0.60238510762071 0.815214506074103 0.907925175392335 GO:0046873 metal ion transmembrane transporter activity 11/573 450/18639 0.0244444444444444 0.795148342059337 0.820426424600854 0.912536963133065 GO:0030170 pyridoxal phosphate binding 1/573 56/18639 0.0178571428571429 0.580871353777113 0.82643351138994 0.917980745689146 GO:0004722 protein serine/threonine phosphatase activity 2/573 103/18639 0.0194174757281553 0.631627103136278 0.829645676583027 0.917980745689146 GO:0005253 monoatomic anion channel activity 2/573 103/18639 0.0194174757281553 0.631627103136278 0.829645676583027 0.917980745689146 GO:0008234 cysteine-type peptidase activity 4/573 187/18639 0.0213903743315508 0.695803118962959 0.830622696181043 0.917980745689146 GO:0016504 peptidase activator activity 1/573 57/18639 0.0175438596491228 0.570680628272251 0.831785370507067 0.917980745689146 GO:0070279 vitamin B6 binding 1/573 57/18639 0.0175438596491228 0.570680628272251 0.831785370507067 0.917980745689146 GO:0008408 3'-5' exonuclease activity 1/573 58/18639 0.0172413793103448 0.560841307095143 0.836972486140446 0.921318550635219 GO:0017116 single-stranded DNA helicase activity 1/573 58/18639 0.0172413793103448 0.560841307095143 0.836972486140446 0.921318550635219 GO:0008509 monoatomic anion transmembrane transporter activity 3/573 149/18639 0.0201342281879195 0.654942197547349 0.840688530173335 0.923103222649476 GO:0015459 potassium channel regulator activity 1/573 59/18639 0.0169491525423729 0.551335522229124 0.841999920909378 0.923103222649476 GO:0000510 H3-H4 histone complex chaperone activity 3/573 151/18639 0.0198675496688742 0.646267466454006 0.847137709528756 0.923103222649476 GO:0140584 chromatin extrusion motor activity 3/573 151/18639 0.0198675496688742 0.646267466454006 0.847137709528756 0.923103222649476 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 3/573 151/18639 0.0198675496688742 0.646267466454006 0.847137709528756 0.923103222649476 GO:0140849 ATP-dependent H2AZ histone chaperone activity 3/573 151/18639 0.0198675496688742 0.646267466454006 0.847137709528756 0.923103222649476 GO:0004843 cysteine-type deubiquitinase activity 2/573 108/18639 0.0185185185185185 0.60238510762071 0.8489492654067 0.923103222649476 GO:0015616 DNA translocase activity 3/573 152/18639 0.0197368421052632 0.642015706806283 0.850276499862289 0.923103222649476 GO:0140674 ATP-dependent histone chaperone activity 3/573 152/18639 0.0197368421052632 0.642015706806283 0.850276499862289 0.923103222649476 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 1/573 61/18639 0.0163934426229508 0.533258947729809 0.851595226528742 0.923103222649476 GO:0016836 hydro-lyase activity 1/573 61/18639 0.0163934426229508 0.533258947729809 0.851595226528742 0.923103222649476 GO:0019905 syntaxin binding 1/573 61/18639 0.0163934426229508 0.533258947729809 0.851595226528742 0.923103222649476 GO:0061775 cohesin loader activity 3/573 153/18639 0.0196078431372549 0.637819525716045 0.853359073697487 0.923839810406936 GO:1901682 sulfur compound transmembrane transporter activity 1/573 63/18639 0.0158730158730159 0.516330092246323 0.860608766688626 0.930505925404453 GO:0004536 DNA nuclease activity 1/573 64/18639 0.015625 0.508262434554974 0.864908463969387 0.933969596073406 GO:0140658 ATP-dependent chromatin remodeler activity 3/573 158/18639 0.0189873417721519 0.617635363509842 0.867954506429667 0.93607245503554 GO:0101005 deubiquitinase activity 2/573 115/18639 0.0173913043478261 0.565718188026406 0.872637696540984 0.9384086343217 GO:0003689 DNA clamp loader activity 3/573 160/18639 0.01875 0.609914921465969 0.873424937813507 0.9384086343217 GO:0015079 potassium ion transmembrane transporter activity 3/573 160/18639 0.01875 0.609914921465969 0.873424937813507 0.9384086343217 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 1/573 67/18639 0.0149253731343284 0.485504415097288 0.877029281160331 0.941094392378592 GO:0042393 histone binding 5/573 247/18639 0.0202429149797571 0.658477648006444 0.880125063037583 0.941607826877125 GO:0005548 phospholipid transporter activity 1/573 68/18639 0.0147058823529412 0.478364644287034 0.880823284062287 0.941607826877125 GO:0030145 manganese ion binding 1/573 68/18639 0.0147058823529412 0.478364644287034 0.880823284062287 0.941607826877125 GO:0140713 histone chaperone activity 3/573 164/18639 0.0182926829268293 0.595038947771677 0.883767496220364 0.943171921763925 GO:0008080 N-acetyltransferase activity 1/573 69/18639 0.0144927536231884 0.471431823355338 0.884500428978141 0.943171921763925 GO:0003697 single-stranded DNA binding 2/573 121/18639 0.0165289256198347 0.537666046471377 0.890170164204703 0.946170506006212 GO:0004540 RNA nuclease activity 2/573 121/18639 0.0165289256198347 0.537666046471377 0.890170164204703 0.946170506006212 GO:0140299 molecular sensor activity 1/573 71/18639 0.0140845070422535 0.458152053683357 0.891518407393285 0.946170506006212 GO:0008528 G protein-coupled peptide receptor activity 2/573 122/18639 0.0163934426229508 0.533258947729809 0.892865125386143 0.946170506006212 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 2/573 122/18639 0.0163934426229508 0.533258947729809 0.892865125386143 0.946170506006212 GO:0004521 RNA endonuclease activity 1/573 73/18639 0.0136986301369863 0.445599942623539 0.898110658682519 0.949853467602001 GO:0005525 GTP binding 8/573 378/18639 0.0211640211640212 0.688440122995097 0.898570299163395 0.949853467602001 GO:0019003 GDP binding 1/573 75/18639 0.0133333333333333 0.433717277486911 0.904302966052698 0.953567507403393 GO:0004519 endonuclease activity 2/573 127/18639 0.015748031496063 0.512264500968793 0.905441447757447 0.953567507403393 GO:0019783 ubiquitin-like protein peptidase activity 2/573 127/18639 0.015748031496063 0.512264500968793 0.905441447757447 0.953567507403393 GO:0051536 iron-sulfur cluster binding 1/573 76/18639 0.0131578947368421 0.428010471204189 0.907256769136721 0.953678334418771 GO:0001653 peptide receptor activity 2/573 128/18639 0.015625 0.508262434554974 0.907785362926788 0.953678334418771 GO:0003724 RNA helicase activity 1/573 77/18639 0.012987012987013 0.422451893656082 0.910119553777386 0.953778425360803 GO:0051540 metal cluster binding 1/573 77/18639 0.012987012987013 0.422451893656082 0.910119553777386 0.953778425360803 GO:0005262 calcium channel activity 2/573 131/18639 0.0152671755725191 0.496622836817074 0.914495093172044 0.95589604643308 GO:0008186 ATP-dependent activity, acting on RNA 1/573 79/18639 0.0126582278481013 0.411756909006561 0.915583181299493 0.95589604643308 GO:0016835 carbon-oxygen lyase activity 1/573 79/18639 0.0126582278481013 0.411756909006561 0.915583181299493 0.95589604643308 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 2/573 132/18639 0.0151515151515152 0.492860542598763 0.916628016356604 0.95589604643308 GO:0051087 protein-folding chaperone binding 2/573 134/18639 0.0149253731343284 0.485504415097288 0.920744831971578 0.959015399559638 GO:0008135 translation factor activity, RNA binding 1/573 83/18639 0.0120481927710843 0.391913202548414 0.925535794614455 0.960963026197123 GO:0004527 exonuclease activity 1/573 84/18639 0.0119047619047619 0.387247569184742 0.927835212036632 0.960963026197123 GO:0019001 guanyl nucleotide binding 8/573 400/18639 0.02 0.650575916230367 0.927982715323549 0.960963026197123 GO:0032561 guanyl ribonucleotide binding 8/573 400/18639 0.02 0.650575916230367 0.927982715323549 0.960963026197123 GO:0015276 ligand-gated monoatomic ion channel activity 3/573 186/18639 0.0161290322580645 0.524657996959973 0.928254190798395 0.960963026197123 GO:0022834 ligand-gated channel activity 3/573 188/18639 0.0159574468085106 0.519076528907207 0.931405330954421 0.961887687240203 GO:0140597 protein carrier chaperone 3/573 188/18639 0.0159574468085106 0.519076528907207 0.931405330954421 0.961887687240203 GO:0015085 calcium ion transmembrane transporter activity 2/573 147/18639 0.0136054421768707 0.442568650496848 0.943177125233827 0.97286550932109 GO:0016887 ATP hydrolysis activity 8/573 417/18639 0.0191846522781775 0.624053636671814 0.945353026490602 0.973930808428045 GO:0016829 lyase activity 3/573 200/18639 0.015 0.487931937172775 0.947783968920919 0.975255968020076 GO:0140104 molecular carrier activity 4/573 249/18639 0.0160642570281124 0.522550936731218 0.950205003953954 0.976567748333859 GO:0005261 monoatomic cation channel activity 6/573 341/18639 0.0175953079178886 0.572354178501789 0.953049442913097 0.978310994411998 GO:0004518 nuclease activity 3/573 209/18639 0.0143540669856459 0.466920514040933 0.957596285566407 0.980853288349521 GO:0008094 ATP-dependent activity, acting on DNA 3/573 210/18639 0.0142857142857143 0.46469708302169 0.958573071004778 0.980853288349521 GO:0008238 exopeptidase activity 1/573 102/18639 0.00980392156862745 0.318909762858023 0.958979799524825 0.980853288349521 GO:0016741 transferase activity, transferring one-carbon groups 3/573 215/18639 0.013953488372093 0.453890174114209 0.963148492050793 0.983444457684343 GO:0000149 SNARE binding 1/573 106/18639 0.00943396226415094 0.306875432184135 0.963821739631956 0.983444457684343 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 2/573 167/18639 0.0119760479041916 0.389566416904411 0.966305084005786 0.984798961211638 GO:0005216 monoatomic ion channel activity 8/573 448/18639 0.0178571428571429 0.580871353777113 0.967733579817442 0.98506633315599 GO:0022836 gated channel activity 5/573 318/18639 0.0157232704402516 0.511459053640225 0.96914768075987 0.98506633315599 GO:0043022 ribosome binding 1/573 112/18639 0.00892857142857143 0.290435676888556 0.970035978307366 0.98506633315599 GO:0003735 structural constituent of ribosome 2/573 175/18639 0.0114285714285714 0.371757666417352 0.972747364266955 0.986308722803735 GO:0009055 electron transfer activity 1/573 116/18639 0.00862068965517241 0.280420653547572 0.973574689997584 0.986308722803735 GO:0016853 isomerase activity 2/573 180/18639 0.0111111111111111 0.361431064572426 0.976151968376561 0.986819069868525 GO:0003924 GTPase activity 5/573 331/18639 0.0151057401812689 0.491371537938343 0.97639492476428 0.986819069868525 GO:0015297 antiporter activity 1/573 135/18639 0.00740740740740741 0.240954043048284 0.985458760861749 0.994011584234204 GO:0008168 methyltransferase activity 2/573 204/18639 0.00980392156862745 0.318909762858023 0.987531580186719 0.994011584234204 GO:0022804 active transmembrane transporter activity 7/573 457/18639 0.0153172866520788 0.498252889891966 0.988006621939269 0.994011584234204 GO:0003730 mRNA 3'-UTR binding 3/573 262/18639 0.0114503816793893 0.372467127612805 0.988178182918276 0.994011584234204 GO:0045182 translation regulator activity 4/573 356/18639 0.0112359550561798 0.365492087769869 0.995602501083236 0.999968507655999 GO:0015078 proton transmembrane transporter activity 1/573 185/18639 0.00540540540540541 0.17583132871091 0.996989590871829 0.999968507655999 GO:0140097 catalytic activity, acting on DNA 3/573 336/18639 0.00892857142857143 0.290435676888556 0.998222158803177 0.999968507655999 GO:0140098 catalytic activity, acting on RNA 3/573 387/18639 0.00775193798449612 0.252161207841227 0.999543791928553 0.999968507655999 GO:0030371 translation repressor activity 1/573 329/18639 0.00303951367781155 0.098871719791849 0.999968507655999 0.999968507655999