ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0003779	actin binding	113/2287	443/18639	0.255079006772009	2.0788883284755	1.01421577320306e-14	1.30529570011234e-11
GO:0005201	extracellular matrix structural constituent	53/2287	168/18639	0.31547619047619	2.57112405521894	3.26898013858033e-11	1.97145344844982e-08
GO:0019838	growth factor binding	46/2287	136/18639	0.338235294117647	2.7566102523213	4.59546258379912e-11	1.97145344844982e-08
GO:0045296	cadherin binding	82/2287	334/18639	0.245508982035928	2.00089283610305	3.62993014949769e-10	1.16793002560088e-07
GO:0005178	integrin binding	47/2287	161/18639	0.291925465838509	2.37918616430432	7.06416674572723e-09	1.65041202507943e-06
GO:0005518	collagen binding	28/2287	72/18639	0.388888888888889	3.16943594228247	8.46534762167188e-09	1.65041202507943e-06
GO:0005539	glycosaminoglycan binding	62/2287	242/18639	0.256198347107438	2.08801092773745	8.97659998100698e-09	1.65041202507943e-06
GO:0050840	extracellular matrix binding	25/2287	67/18639	0.373134328358209	3.04103661839469	1.36947096187793e-07	2.20313640992112e-05
GO:0005520	insulin-like growth factor binding	12/2287	19/18639	0.631578947368421	5.14735461303017	2.48104068957078e-07	3.54788818608621e-05
GO:0140297	DNA-binding transcription factor binding	98/2287	488/18639	0.200819672131148	1.63667593740816	4.55561281738848e-07	5.80905007588037e-05
GO:0008201	heparin binding	45/2287	172/18639	0.261627906976744	2.13226172196744	4.96500006485502e-07	5.80905007588037e-05
GO:0051371	muscle alpha-actinin binding	10/2287	15/18639	0.666666666666667	5.43331875819851	1.26839392856878e-06	0.000136035248839002
GO:0042805	actinin binding	16/2287	37/18639	0.432432432432432	3.52431487018282	2.53850263797467e-06	0.000251311761159492
GO:0031994	insulin-like growth factor I binding	9/2287	13/18639	0.692307692307692	5.64229255659076	2.79093528348724e-06	0.000256566693560577
GO:0001968	fibronectin binding	14/2287	30/18639	0.466666666666667	3.80332313073896	3.58688526508134e-06	0.000307754755743979
GO:0051015	actin filament binding	49/2287	209/18639	0.23444976076555	1.91076042453393	4.93685107168198e-06	0.000397107958078419
GO:0048407	platelet-derived growth factor binding	8/2287	11/18639	0.727272727272727	5.92725682712565	5.9405120483536e-06	0.000449731706248887
GO:0005161	platelet-derived growth factor receptor binding	9/2287	14/18639	0.642857142857143	5.23927165969142	6.9588838507338e-06	0.000497560195327466
GO:0050431	transforming growth factor beta binding	12/2287	24/18639	0.5	4.07498906864889	7.35318578448654e-06	0.000498081584454431
GO:1901681	sulfur compound binding	59/2287	275/18639	0.214545454545455	1.74854076400207	1.11848632327823e-05	0.000719745949029542
GO:0048029	monosaccharide binding	23/2287	74/18639	0.310810810810811	2.5331013129439	1.54549002401783e-05	0.000947164600433785
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	69/2287	349/18639	0.197707736389685	1.61131372915056	3.71845039536429e-05	0.00217529348128811
GO:0001221	transcription coregulator binding	30/2287	115/18639	0.260869565217391	2.12608125320811	4.00200020760046e-05	0.002239380116166
GO:0031418	L-ascorbic acid binding	10/2287	20/18639	0.5	4.07498906864889	4.35029125364225e-05	0.00233284368476566
GO:0051393	alpha-actinin binding	12/2287	28/18639	0.428571428571429	3.49284777312762	5.15438603207759e-05	0.00265347792931354
GO:0031625	ubiquitin protein ligase binding	61/2287	302/18639	0.201986754966887	1.64618763700385	5.39381869510414e-05	0.00266994025407655
GO:0005516	calmodulin binding	45/2287	207/18639	0.217391304347826	1.77173437767343	8.45797322389518e-05	0.00403163390339004
GO:0031072	heat shock protein binding	32/2287	131/18639	0.244274809160305	1.99083435414907	8.98694283730999e-05	0.0041307840827207
GO:0019902	phosphatase binding	42/2287	190/18639	0.221052631578947	1.80157411456056	9.66925949256474e-05	0.00429115067825201
GO:0048156	tau protein binding	15/2287	43/18639	0.348837209302326	2.84301562928992	0.000107099592238589	0.00450597830799508
GO:0044389	ubiquitin-like protein ligase binding	63/2287	322/18639	0.195652173913043	1.59456093990609	0.000108535608040286	0.00450597830799508
GO:0046332	SMAD binding	22/2287	79/18639	0.278481012658228	2.2696141648171	0.000147817911934482	0.00594505164561496
GO:0051287	NAD binding	17/2287	54/18639	0.314814814814815	2.56573385803819	0.000162751312779061	0.00634730119838336
GO:0004674	protein serine/threonine kinase activity	79/2287	433/18639	0.182448036951501	1.48694751234763	0.000180408210150241	0.0068289813665694
GO:0031543	peptidyl-proline dioxygenase activity	7/2287	12/18639	0.583333333333333	4.7541539134237	0.000187151108784708	0.00688181362874053
GO:0019903	protein phosphatase binding	33/2287	144/18639	0.229166666666667	1.86770332313074	0.000257187919209932	0.00902575747945929
GO:0008083	growth factor activity	36/2287	162/18639	0.222222222222222	1.81110625273284	0.000263790802793599	0.00902575747945929
GO:0051082	unfolded protein binding	29/2287	121/18639	0.239669421487603	1.95330054530277	0.000266494781833297	0.00902575747945929
GO:0003712	transcription coregulator activity	87/2287	495/18639	0.175757575757576	1.4324203998887	0.000321067731228908	0.010595235130554
GO:0140416	transcription regulator inhibitor activity	12/2287	33/18639	0.363636363636364	2.96362841356283	0.000333671220606576	0.0107358715230166
GO:0019199	transmembrane receptor protein kinase activity	21/2287	78/18639	0.269230769230769	2.19422488311863	0.000344685818889193	0.0108197719246437
GO:0043236	laminin binding	11/2287	29/18639	0.379310344827586	3.09137101759571	0.000385702082180734	0.0116705408060011
GO:0001217	DNA-binding transcription repressor activity	54/2287	278/18639	0.194244604316547	1.58308927846791	0.000389924828794131	0.0116705408060011
GO:0002020	protease binding	31/2287	136/18639	0.227941176470588	1.85771560482523	0.00042963617929767	0.0125668582444568
GO:0004029	aldehyde dehydrogenase (NAD+) activity	8/2287	17/18639	0.470588235294118	3.8352838293166	0.000441459870037254	0.0126257522830655
GO:0030020	extracellular matrix structural constituent conferring tensile strength	14/2287	44/18639	0.318181818181818	2.59317486186747	0.000535022099139681	0.0146047511762595
GO:0001222	transcription corepressor binding	15/2287	49/18639	0.306122448979592	2.49489126651973	0.00054469934456912	0.0146047511762595
GO:0060590	ATPase regulator activity	15/2287	49/18639	0.306122448979592	2.49489126651973	0.00054469934456912	0.0146047511762595
GO:0019955	cytokine binding	32/2287	144/18639	0.222222222222222	1.81110625273284	0.00056247708230702	0.0147736327536558
GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity	8/2287	18/18639	0.444444444444444	3.62221250546568	0.000709471618081001	0.0179717745614369
GO:0140272	exogenous protein binding	21/2287	82/18639	0.25609756097561	2.0871895229665	0.000712168222714282	0.0179717745614369
GO:0005543	phospholipid binding	85/2287	497/18639	0.17102615694165	1.3938594399805	0.000892528425565969	0.0203998836513192
GO:0141003	histone H2AX kinase activity	64/2287	354/18639	0.180790960451977	1.47344237510468	0.000899968878475692	0.0203998836513192
GO:0005536	D-glucose binding	6/2287	11/18639	0.545454545454545	4.44544262034424	0.000903099797677929	0.0203998836513192
GO:0043522	leucine zipper domain binding	6/2287	11/18639	0.545454545454545	4.44544262034424	0.000903099797677929	0.0203998836513192
GO:0140537	transcription regulator activator activity	6/2287	11/18639	0.545454545454545	4.44544262034424	0.000903099797677929	0.0203998836513192
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	51/2287	268/18639	0.190298507462687	1.55092867538129	0.000903491350524628	0.0203998836513192
GO:0000287	magnesium ion binding	45/2287	230/18639	0.195652173913043	1.59456093990609	0.000975106237735366	0.0216372711718175
GO:0005080	protein kinase C binding	15/2287	52/18639	0.288461538461538	2.35095523191282	0.00108495092772522	0.022569107006174
GO:0000774	adenyl-nucleotide exchange factor activity	7/2287	15/18639	0.466666666666667	3.80332313073896	0.00108716873246656	0.022569107006174
GO:0031005	filamin binding	7/2287	15/18639	0.466666666666667	3.80332313073896	0.00108716873246656	0.022569107006174
GO:0043394	proteoglycan binding	12/2287	37/18639	0.324324324324324	2.64323615263711	0.00109019146664772	0.022569107006174
GO:0008307	structural constituent of muscle	13/2287	42/18639	0.30952380952381	2.52261228059217	0.00112013539318608	0.022569107006174
GO:0140996	histone H3 kinase activity	64/2287	357/18639	0.179271708683473	1.46106050640632	0.00112231767552069	0.022569107006174
GO:0035173	histone kinase activity	64/2287	360/18639	0.177777777777778	1.44888500218627	0.00139212331488542	0.0275640416347314
GO:0001618	virus receptor activity	20/2287	81/18639	0.246913580246914	2.01234028081426	0.00153378803986973	0.0295331182815808
GO:0004857	enzyme inhibitor activity	72/2287	416/18639	0.173076923076923	1.41057313914769	0.00153746614208696	0.0295331182815808
GO:0008179	adenylate cyclase binding	6/2287	12/18639	0.5	4.07498906864889	0.00161904848657115	0.0297673628888153
GO:0017166	vinculin binding	6/2287	12/18639	0.5	4.07498906864889	0.00161904848657115	0.0297673628888153
GO:0035259	nuclear glucocorticoid receptor binding	6/2287	12/18639	0.5	4.07498906864889	0.00161904848657115	0.0297673628888153
GO:0005024	transforming growth factor beta receptor activity	7/2287	16/18639	0.4375	3.56561543506777	0.00172910558006581	0.0309077622436764
GO:0030275	LRR domain binding	7/2287	16/18639	0.4375	3.56561543506777	0.00172910558006581	0.0309077622436764
GO:0001223	transcription coactivator binding	13/2287	44/18639	0.295454545454545	2.4079480860198	0.00180186403693896	0.0317671098019238
GO:0042562	hormone binding	22/2287	94/18639	0.234042553191489	1.90744169170799	0.00193309382937439	0.0336201588973628
GO:0016922	nuclear receptor binding	29/2287	137/18639	0.211678832116788	1.72517785388055	0.00219140889504531	0.0376045766389776
GO:0051721	protein phosphatase 2A binding	10/2287	30/18639	0.333333333333333	2.71665937909926	0.00222353279531998	0.0376537724681161
GO:0071949	FAD binding	12/2287	40/18639	0.3	2.44499344118933	0.00231660651915223	0.0382240075660118
GO:0140662	ATP-dependent protein folding chaperone	12/2287	40/18639	0.3	2.44499344118933	0.00231660651915223	0.0382240075660118
GO:0106310	protein serine kinase activity	63/2287	361/18639	0.174515235457064	1.42229535360044	0.00238510527159711	0.0388560820828542
GO:0051117	ATPase binding	20/2287	84/18639	0.238095238095238	1.9404709850709	0.00244640434241265	0.0393565298585635
GO:0005172	vascular endothelial growth factor receptor binding	6/2287	13/18639	0.461538461538462	3.76152837106051	0.0026960930779384	0.0428379233494657
GO:0042826	histone deacetylase binding	27/2287	127/18639	0.21259842519685	1.73267251737827	0.00286058280310938	0.0448116316208541
GO:1990841	promoter-specific chromatin binding	17/2287	68/18639	0.25	2.03749453432444	0.00291012683151631	0.0448116316208541
GO:0070325	lipoprotein particle receptor binding	10/2287	31/18639	0.32258064516129	2.62902520557993	0.00292629105346813	0.0448116316208541
GO:0003713	transcription coactivator activity	47/2287	256/18639	0.18359375	1.49628504864451	0.00295958716998648	0.0448116316208541
GO:0004713	protein tyrosine kinase activity	29/2287	140/18639	0.207142857142857	1.68820975701168	0.0030681897045857	0.0459158156953697
GO:0044183	protein folding chaperone	18/2287	75/18639	0.24	1.95599475295146	0.00358794671568157	0.0530768669319791
GO:0051879	Hsp90 protein binding	12/2287	42/18639	0.285714285714286	2.32856518208508	0.00363325987013002	0.0531364256006516
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	7/2287	18/18639	0.388888888888889	3.16943594228247	0.00385290318736158	0.0557155775520713
GO:0044325	transmembrane transporter binding	28/2287	136/18639	0.205882352941176	1.67793667532601	0.00391630297182989	0.0560031324971674
GO:0005522	profilin binding	5/2287	10/18639	0.5	4.07498906864889	0.00409089969649945	0.0578570099933494
GO:0008191	metalloendopeptidase inhibitor activity	6/2287	14/18639	0.428571428571429	3.49284777312762	0.00423195571616365	0.0579417766670491
GO:0008195	phosphatidate phosphatase activity	6/2287	14/18639	0.428571428571429	3.49284777312762	0.00423195571616365	0.0579417766670491
GO:0042043	neurexin family protein binding	6/2287	14/18639	0.428571428571429	3.49284777312762	0.00423195571616365	0.0579417766670491
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	79/2287	484/18639	0.163223140495868	1.3302650265424	0.00475956330650147	0.0644795576364988
GO:0019001	guanyl nucleotide binding	67/2287	400/18639	0.1675	1.36512133799738	0.00486944837410364	0.0646080418296019
GO:0032561	guanyl ribonucleotide binding	67/2287	400/18639	0.1675	1.36512133799738	0.00486944837410364	0.0646080418296019
GO:0035091	phosphatidylinositol binding	50/2287	284/18639	0.176056338028169	1.43485530586228	0.00528589332651398	0.06941780317575
GO:0042577	lipid phosphatase activity	7/2287	19/18639	0.368421052631579	3.0026235242676	0.00546205283433408	0.0706536243489161
GO:0003714	transcription corepressor activity	38/2287	204/18639	0.186274509803922	1.51813318243782	0.00548979210170288	0.0706536243489161
GO:0030246	carbohydrate binding	49/2287	280/18639	0.175	1.42624617402711	0.00642186456603574	0.0818310861038416
GO:0048185	activin binding	5/2287	11/18639	0.454545454545455	3.70453551695353	0.00674739961218404	0.084309740785251
GO:0097493	structural molecule activity conferring elasticity	5/2287	11/18639	0.454545454545455	3.70453551695353	0.00674739961218404	0.084309740785251
GO:0001216	DNA-binding transcription activator activity	79/2287	491/18639	0.160896130346232	1.3112999446976	0.00684922745882446	0.084587282321693
GO:0005525	GTP binding	63/2287	378/18639	0.166666666666667	1.35832968954963	0.00690106032927565	0.084587282321693
GO:0004866	endopeptidase inhibitor activity	31/2287	161/18639	0.192546583850932	1.56925044879646	0.00702323986743287	0.085272733107416
GO:0005548	phospholipid transporter activity	16/2287	68/18639	0.235294117647059	1.9176419146583	0.00715090407296803	0.0860113415131763
GO:0050660	flavin adenine dinucleotide binding	19/2287	86/18639	0.22093023255814	1.80057656521695	0.0073548426672999	0.0872588368105714
GO:0004679	AMP-activated protein kinase activity	44/2287	248/18639	0.17741935483871	1.44596386306896	0.00739022005621778	0.0872588368105714
GO:0042974	nuclear retinoic acid receptor binding	8/2287	25/18639	0.32	2.60799300393529	0.0079809143193422	0.0921562456647137
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	8/2287	25/18639	0.32	2.60799300393529	0.0079809143193422	0.0921562456647137
GO:0030414	peptidase inhibitor activity	32/2287	169/18639	0.189349112426035	1.54319112658893	0.00801981314253919	0.0921562456647137
GO:0070411	I-SMAD binding	6/2287	16/18639	0.375	3.05624180148666	0.00908810524709923	0.10350788896475
GO:0036122	BMP binding	7/2287	21/18639	0.333333333333333	2.71665937909926	0.010113227210571	0.114173012456183
GO:0043548	phosphatidylinositol 3-kinase binding	8/2287	26/18639	0.307692307692308	2.50768558070701	0.0103115777358276	0.115163293548008
GO:0005527	macrolide binding	5/2287	12/18639	0.416666666666667	3.39582422387407	0.0104105075590504	0.115163293548008
GO:0004867	serine-type endopeptidase inhibitor activity	20/2287	95/18639	0.210526315789474	1.71578487101006	0.0104693903225462	0.115163293548008
GO:0004879	nuclear receptor activity	14/2287	59/18639	0.23728813559322	1.93389311732489	0.0106127883784237	0.115751344432468
GO:0035402	histone H3T11 kinase activity	43/2287	247/18639	0.174089068825911	1.4188221048737	0.0111016966309688	0.120066248437452
GO:0032266	phosphatidylinositol-3-phosphate binding	12/2287	48/18639	0.25	2.03749453432444	0.0114289787319882	0.122575796900573
GO:0051087	protein-folding chaperone binding	26/2287	134/18639	0.194029850746269	1.58133904156524	0.0115827140701012	0.123197958745621
GO:0035401	histone H3Y41 kinase activity	23/2287	115/18639	0.2	1.62999562745955	0.0118715860735094	0.124217327452086
GO:0140801	histone H2AXY142 kinase activity	23/2287	115/18639	0.2	1.62999562745955	0.0118715860735094	0.124217327452086
GO:0031267	small GTPase binding	48/2287	283/18639	0.169611307420495	1.38232844731552	0.0122728459020555	0.125838916391553
GO:0004714	transmembrane receptor protein tyrosine kinase activity	14/2287	60/18639	0.233333333333333	1.90166156536948	0.0123198939124597	0.125838916391553
GO:0098531	ligand-modulated transcription factor activity	14/2287	60/18639	0.233333333333333	1.90166156536948	0.0123198939124597	0.125838916391553
GO:0048038	quinone binding	6/2287	17/18639	0.352941176470588	2.87646287198745	0.012610458521652	0.12779259934934
GO:0050321	tau-protein kinase activity	7/2287	22/18639	0.318181818181818	2.59317486186747	0.0132918869465963	0.133645769533354
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	42/2287	243/18639	0.172839506172839	1.40863819656998	0.0134642451090044	0.134329329110765
GO:0070123	transforming growth factor beta receptor activity, type III	5/2287	13/18639	0.384615384615385	3.13460697588376	0.0152320166097454	0.134527938758248
GO:0004676	3-phosphoinositide-dependent protein kinase activity	42/2287	245/18639	0.171428571428571	1.39713910925105	0.0153656620026904	0.134527938758248
GO:0004711	ribosomal protein S6 kinase activity	42/2287	245/18639	0.171428571428571	1.39713910925105	0.0153656620026904	0.134527938758248
GO:0035175	histone H3S10 kinase activity	42/2287	245/18639	0.171428571428571	1.39713910925105	0.0153656620026904	0.134527938758248
GO:0035979	histone H2AXS139 kinase activity	42/2287	245/18639	0.171428571428571	1.39713910925105	0.0153656620026904	0.134527938758248
GO:0044022	histone H3S28 kinase activity	42/2287	245/18639	0.171428571428571	1.39713910925105	0.0153656620026904	0.134527938758248
GO:0044023	histone H4S1 kinase activity	42/2287	245/18639	0.171428571428571	1.39713910925105	0.0153656620026904	0.134527938758248
GO:0044024	histone H2AS1 kinase activity	42/2287	245/18639	0.171428571428571	1.39713910925105	0.0153656620026904	0.134527938758248
GO:0044025	histone H2BS14 kinase activity	42/2287	245/18639	0.171428571428571	1.39713910925105	0.0153656620026904	0.134527938758248
GO:0072354	histone H3T3 kinase activity	42/2287	245/18639	0.171428571428571	1.39713910925105	0.0153656620026904	0.134527938758248
GO:0072371	histone H2AS121 kinase activity	42/2287	245/18639	0.171428571428571	1.39713910925105	0.0153656620026904	0.134527938758248
GO:0072518	Rho-dependent protein serine/threonine kinase activity	42/2287	245/18639	0.171428571428571	1.39713910925105	0.0153656620026904	0.134527938758248
GO:0140823	histone H2BS36 kinase activity	42/2287	245/18639	0.171428571428571	1.39713910925105	0.0153656620026904	0.134527938758248
GO:0140855	histone H3S57 kinase activity	42/2287	245/18639	0.171428571428571	1.39713910925105	0.0153656620026904	0.134527938758248
GO:0140995	histone H2A kinase activity	42/2287	245/18639	0.171428571428571	1.39713910925105	0.0153656620026904	0.134527938758248
GO:0140997	histone H4 kinase activity	42/2287	245/18639	0.171428571428571	1.39713910925105	0.0153656620026904	0.134527938758248
GO:0140998	histone H2B kinase activity	42/2287	245/18639	0.171428571428571	1.39713910925105	0.0153656620026904	0.134527938758248
GO:1990244	histone H2AT120 kinase activity	42/2287	245/18639	0.171428571428571	1.39713910925105	0.0153656620026904	0.134527938758248
GO:0051020	GTPase binding	52/2287	315/18639	0.165079365079365	1.34539321631582	0.0156221254542417	0.135849158510872
GO:0061135	endopeptidase regulator activity	33/2287	184/18639	0.179347826086957	1.46168086158058	0.0158379152809077	0.136801321923008
GO:0032934	sterol binding	15/2287	68/18639	0.220588235294118	1.79778929499216	0.016335686033593	0.138818609175664
GO:0004677	DNA-dependent protein kinase activity	42/2287	246/18639	0.170731707317073	1.39145968197767	0.016395049413132	0.138818609175664
GO:0140857	histone H3T45 kinase activity	42/2287	246/18639	0.170731707317073	1.39145968197767	0.016395049413132	0.138818609175664
GO:0005319	lipid transporter activity	32/2287	178/18639	0.179775280898876	1.46516460895241	0.0167510197434861	0.140642846774875
GO:0003746	translation elongation factor activity	6/2287	18/18639	0.333333333333333	2.71665937909926	0.0169892361887973	0.140642846774875
GO:1901981	phosphatidylinositol phosphate binding	33/2287	185/18639	0.178378378378378	1.45377988395041	0.0170735308573101	0.140642846774875
GO:0005158	insulin receptor binding	7/2287	23/18639	0.304347826086957	2.4804281287428	0.0171272753361185	0.140642846774875
GO:0061134	peptidase regulator activity	39/2287	226/18639	0.172566371681416	1.40641215643634	0.0171568973921176	0.140642846774875
GO:0033218	amide binding	42/2287	247/18639	0.17004048582996	1.38582624196966	0.0174795412026484	0.141485342942192
GO:0035403	histone H3T6 kinase activity	42/2287	247/18639	0.17004048582996	1.38582624196966	0.0174795412026484	0.141485342942192
GO:0003725	double-stranded RNA binding	16/2287	75/18639	0.213333333333333	1.73866200262352	0.0182763059588679	0.147010036056644
GO:0008376	acetylgalactosaminyltransferase activity	9/2287	34/18639	0.264705882352941	2.15734715399059	0.018620065058835	0.148844867892674
GO:0042277	peptide binding	42/2287	249/18639	0.168674698795181	1.37469510749601	0.0198219241528807	0.157474175214552
GO:0005496	steroid binding	21/2287	108/18639	0.194444444444444	1.58471797114123	0.0211859322140677	0.167277881960154
GO:0052816	long-chain fatty acyl-CoA hydrolase activity	5/2287	14/18639	0.357142857142857	2.91070647760635	0.0213431615506241	0.167491761680813
GO:0004622	lysophospholipase activity	7/2287	24/18639	0.291666666666667	2.37707695671185	0.0216807992144344	0.168091497523959
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	7/2287	24/18639	0.291666666666667	2.37707695671185	0.0216807992144344	0.168091497523959
GO:0015171	amino acid transmembrane transporter activity	20/2287	102/18639	0.196078431372549	1.59803492888192	0.0221475397352171	0.170681937959428
GO:0043395	heparan sulfate proteoglycan binding	6/2287	19/18639	0.315789473684211	2.57367730651509	0.0223094746600879	0.170906511235317
GO:0140828	metal cation:monoatomic cation antiporter activity	10/2287	41/18639	0.24390243902439	1.98779954568238	0.0237064103083992	0.180533432348578
GO:0120013	lipid transfer activity	14/2287	65/18639	0.215384615384615	1.7553799064949	0.0242396930172164	0.183508734783279
GO:0035925	mRNA 3'-UTR AU-rich region binding	8/2287	30/18639	0.266666666666667	2.17332750327941	0.0247935738316996	0.186308529150837
GO:0004382	GDP phosphatase activity	4/2287	10/18639	0.4	3.25999125491911	0.0257676132003489	0.186308529150837
GO:0005528	FK506 binding	4/2287	10/18639	0.4	3.25999125491911	0.0257676132003489	0.186308529150837
GO:0008140	cAMP response element binding protein binding	4/2287	10/18639	0.4	3.25999125491911	0.0257676132003489	0.186308529150837
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	4/2287	10/18639	0.4	3.25999125491911	0.0257676132003489	0.186308529150837
GO:0031996	thioesterase binding	4/2287	10/18639	0.4	3.25999125491911	0.0257676132003489	0.186308529150837
GO:0035374	chondroitin sulfate binding	4/2287	10/18639	0.4	3.25999125491911	0.0257676132003489	0.186308529150837
GO:0043121	neurotrophin binding	4/2287	10/18639	0.4	3.25999125491911	0.0257676132003489	0.186308529150837
GO:0005126	cytokine receptor binding	45/2287	275/18639	0.163636363636364	1.33363278610327	0.026542599388314	0.190315900405622
GO:0019208	phosphatase regulator activity	22/2287	117/18639	0.188034188034188	1.53247452154317	0.0266176084483388	0.190315900405622
GO:1902936	phosphatidylinositol bisphosphate binding	21/2287	111/18639	0.189189189189189	1.54188775570498	0.028024182059739	0.199265869120907
GO:0140693	molecular condensate scaffold activity	11/2287	48/18639	0.229166666666667	1.86770332313074	0.0282527950918289	0.199787622435076
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	6/2287	20/18639	0.3	2.44499344118933	0.0286452892652205	0.20070592569796
GO:0005523	tropomyosin binding	5/2287	15/18639	0.333333333333333	2.71665937909926	0.0288505021399554	0.20070592569796
GO:0045504	dynein heavy chain binding	5/2287	15/18639	0.333333333333333	2.71665937909926	0.0288505021399554	0.20070592569796
GO:0070273	phosphatidylinositol-4-phosphate binding	8/2287	31/18639	0.258064516129032	2.10322016446394	0.0299303288743346	0.207098565920799
GO:0005200	structural constituent of cytoskeleton	21/2287	112/18639	0.1875	1.52812090074333	0.0306394228982218	0.210871322299527
GO:0030295	protein kinase activator activity	25/2287	139/18639	0.179856115107914	1.46582340598881	0.0314340714960301	0.21518962774144
GO:0005160	transforming growth factor beta receptor binding	7/2287	26/18639	0.269230769230769	2.19422488311863	0.0331600417793797	0.22580409402149
GO:0016791	phosphatase activity	44/2287	273/18639	0.161172161172161	1.31354958989415	0.0350896597743933	0.227530833815156
GO:0005123	death receptor binding	6/2287	21/18639	0.285714285714286	2.32856518208508	0.0360581140870803	0.227530833815156
GO:0005248	voltage-gated sodium channel activity	6/2287	21/18639	0.285714285714286	2.32856518208508	0.0360581140870803	0.227530833815156
GO:0010314	phosphatidylinositol-5-phosphate binding	6/2287	21/18639	0.285714285714286	2.32856518208508	0.0360581140870803	0.227530833815156
GO:0019200	carbohydrate kinase activity	6/2287	21/18639	0.285714285714286	2.32856518208508	0.0360581140870803	0.227530833815156
GO:0051010	microtubule plus-end binding	6/2287	21/18639	0.285714285714286	2.32856518208508	0.0360581140870803	0.227530833815156
GO:0003924	GTPase activity	52/2287	331/18639	0.157099697885196	1.28035910314044	0.0361404795458179	0.227530833815156
GO:0002162	dystroglycan binding	4/2287	11/18639	0.363636363636364	2.96362841356283	0.0366363066793002	0.227530833815156
GO:0003953	NAD+ nucleosidase activity	4/2287	11/18639	0.363636363636364	2.96362841356283	0.0366363066793002	0.227530833815156
GO:0004016	adenylate cyclase activity	4/2287	11/18639	0.363636363636364	2.96362841356283	0.0366363066793002	0.227530833815156
GO:0008526	phosphatidylinositol transfer activity	4/2287	11/18639	0.363636363636364	2.96362841356283	0.0366363066793002	0.227530833815156
GO:0015173	aromatic amino acid transmembrane transporter activity	4/2287	11/18639	0.363636363636364	2.96362841356283	0.0366363066793002	0.227530833815156
GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor	4/2287	11/18639	0.363636363636364	2.96362841356283	0.0366363066793002	0.227530833815156
GO:0050998	nitric-oxide synthase binding	4/2287	11/18639	0.363636363636364	2.96362841356283	0.0366363066793002	0.227530833815156
GO:0070697	activin receptor binding	4/2287	11/18639	0.363636363636364	2.96362841356283	0.0366363066793002	0.227530833815156
GO:0019209	kinase activator activity	26/2287	148/18639	0.175675675675676	1.43175291601177	0.0371639501444362	0.227530833815156
GO:0005006	epidermal growth factor receptor activity	11/2287	50/18639	0.22	1.79299519020551	0.0372389052603576	0.227530833815156
GO:0005017	platelet-derived growth factor receptor activity	11/2287	50/18639	0.22	1.79299519020551	0.0372389052603576	0.227530833815156
GO:0005019	platelet-derived growth factor beta-receptor activity	11/2287	50/18639	0.22	1.79299519020551	0.0372389052603576	0.227530833815156
GO:0001046	core promoter sequence-specific DNA binding	10/2287	44/18639	0.227272727272727	1.85226775847677	0.0374435373318396	0.227530833815156
GO:0005159	insulin-like growth factor receptor binding	5/2287	16/18639	0.3125	2.54686816790555	0.0378334098185263	0.227530833815156
GO:0015385	sodium:proton antiporter activity	5/2287	16/18639	0.3125	2.54686816790555	0.0378334098185263	0.227530833815156
GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	5/2287	16/18639	0.3125	2.54686816790555	0.0378334098185263	0.227530833815156
GO:0016722	oxidoreductase activity, acting on metal ions	5/2287	16/18639	0.3125	2.54686816790555	0.0378334098185263	0.227530833815156
GO:0140327	flippase activity	5/2287	16/18639	0.3125	2.54686816790555	0.0378334098185263	0.227530833815156
GO:0098631	cell adhesion mediator activity	15/2287	76/18639	0.197368421052632	1.60854831657193	0.04129325268933	0.245219449128588
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	17/2287	89/18639	0.191011235955056	1.55673739701193	0.0413462474443696	0.245219449128588
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	17/2287	89/18639	0.191011235955056	1.55673739701193	0.0413462474443696	0.245219449128588
GO:0071889	14-3-3 protein binding	8/2287	33/18639	0.242424242424242	1.97575227570855	0.0422925109451013	0.249219882648937
GO:0005010	insulin-like growth factor receptor activity	11/2287	51/18639	0.215686274509804	1.75783842177011	0.0424080452992364	0.249219882648937
GO:0140303	intramembrane lipid transporter activity	10/2287	45/18639	0.222222222222222	1.81110625273284	0.0430403832929546	0.251026709024182
GO:0001540	amyloid-beta binding	16/2287	83/18639	0.192771084337349	1.57108012285258	0.0434956923950215	0.251026709024182
GO:0008135	translation factor activity, RNA binding	16/2287	83/18639	0.192771084337349	1.57108012285258	0.0434956923950215	0.251026709024182
GO:0030165	PDZ domain binding	16/2287	83/18639	0.192771084337349	1.57108012285258	0.0434956923950215	0.251026709024182
GO:0019210	kinase inhibitor activity	17/2287	90/18639	0.188888888888889	1.53944031482291	0.0453696876171602	0.259376787295036
GO:0140793	histone H2AXY142 phosphatase activity	17/2287	90/18639	0.188888888888889	1.53944031482291	0.0453696876171602	0.259376787295036
GO:0004222	metalloendopeptidase activity	20/2287	110/18639	0.181818181818182	1.48181420678141	0.0455471281497111	0.259376787295036
GO:0004860	protein kinase inhibitor activity	16/2287	84/18639	0.19047619047619	1.55237678805672	0.0478472879514045	0.261525660041602
GO:0180051	translation factor activity	16/2287	84/18639	0.19047619047619	1.55237678805672	0.0478472879514045	0.261525660041602
GO:0045499	chemorepellent activity	7/2287	28/18639	0.25	2.03749453432444	0.0480945033880022	0.261525660041602
GO:0051019	mitogen-activated protein kinase binding	7/2287	28/18639	0.25	2.03749453432444	0.0480945033880022	0.261525660041602
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	7/2287	28/18639	0.25	2.03749453432444	0.0480945033880022	0.261525660041602
GO:0008429	phosphatidylethanolamine binding	5/2287	17/18639	0.294117647058824	2.39705239332287	0.0483429728588905	0.261525660041602
GO:0032977	membrane insertase activity	5/2287	17/18639	0.294117647058824	2.39705239332287	0.0483429728588905	0.261525660041602
GO:0046965	nuclear retinoid X receptor binding	5/2287	17/18639	0.294117647058824	2.39705239332287	0.0483429728588905	0.261525660041602
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	10/2287	46/18639	0.217391304347826	1.77173437767343	0.0491797115404748	0.261525660041602
GO:0051427	hormone receptor binding	8/2287	34/18639	0.235294117647059	1.9176419146583	0.0495763404485678	0.261525660041602
GO:0019207	kinase regulator activity	45/2287	287/18639	0.156794425087108	1.2778711365101	0.0496536787135366	0.261525660041602
GO:0005025	transforming growth factor beta receptor activity, type I	4/2287	12/18639	0.333333333333333	2.71665937909926	0.0497492062394252	0.261525660041602
GO:0005026	transforming growth factor beta receptor activity, type II	4/2287	12/18639	0.333333333333333	2.71665937909926	0.0497492062394252	0.261525660041602
GO:0005165	neurotrophin receptor binding	4/2287	12/18639	0.333333333333333	2.71665937909926	0.0497492062394252	0.261525660041602
GO:0016361	activin receptor activity, type I	4/2287	12/18639	0.333333333333333	2.71665937909926	0.0497492062394252	0.261525660041602
GO:0016362	activin receptor activity, type II	4/2287	12/18639	0.333333333333333	2.71665937909926	0.0497492062394252	0.261525660041602
GO:0017002	activin receptor activity	4/2287	12/18639	0.333333333333333	2.71665937909926	0.0497492062394252	0.261525660041602
GO:0035014	phosphatidylinositol 3-kinase regulator activity	4/2287	12/18639	0.333333333333333	2.71665937909926	0.0497492062394252	0.261525660041602
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	9/2287	40/18639	0.225	1.833745080892	0.0497853820592017	0.261525660041602
GO:0004725	protein tyrosine phosphatase activity	18/2287	98/18639	0.183673469387755	1.49693475991184	0.0511833935765791	0.267776534687225
GO:0001786	phosphatidylserine binding	12/2287	59/18639	0.203389830508475	1.65762267199277	0.0522129449678606	0.272056923779905
GO:0005003	ephrin receptor activity	11/2287	53/18639	0.207547169811321	1.69150489642029	0.0541812655844335	0.276171372597235
GO:0005005	transmembrane-ephrin receptor activity	11/2287	53/18639	0.207547169811321	1.69150489642029	0.0541812655844335	0.276171372597235
GO:0005246	calcium channel regulator activity	11/2287	53/18639	0.207547169811321	1.69150489642029	0.0541812655844335	0.276171372597235
GO:0038064	collagen receptor activity	11/2287	53/18639	0.207547169811321	1.69150489642029	0.0541812655844335	0.276171372597235
GO:0017134	fibroblast growth factor binding	6/2287	23/18639	0.260869565217391	2.12608125320811	0.0542900988866359	0.276171372597235
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	6/2287	23/18639	0.260869565217391	2.12608125320811	0.0542900988866359	0.276171372597235
GO:0015085	calcium ion transmembrane transporter activity	25/2287	147/18639	0.170068027210884	1.38605070362207	0.056117105003489	0.284341394249962
GO:0015631	tubulin binding	58/2287	385/18639	0.150649350649351	1.22778891419031	0.0566220493492646	0.285774813774524
GO:0099604	ligand-gated calcium channel activity	7/2287	29/18639	0.241379310344828	1.96723610210636	0.0569363679184406	0.28604497866193
GO:0017080	sodium channel regulator activity	9/2287	41/18639	0.219512195121951	1.78901959111414	0.057120092864115	0.28604497866193
GO:0016209	antioxidant activity	16/2287	86/18639	0.186046511627907	1.51627500228796	0.0574509578999158	0.286586755105394
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	12/2287	60/18639	0.2	1.62999562745955	0.0582795015567276	0.289597368739415
GO:0032182	ubiquitin-like protein binding	21/2287	120/18639	0.175	1.42624617402711	0.0585295718976365	0.289721380893301
GO:0004970	glutamate-gated receptor activity	5/2287	18/18639	0.277777777777778	2.26388281591605	0.060402102347388	0.296547082872611
GO:0031690	adrenergic receptor binding	5/2287	18/18639	0.277777777777778	2.26388281591605	0.060402102347388	0.296547082872611
GO:0015485	cholesterol binding	11/2287	54/18639	0.203703703703704	1.66018073167177	0.060812279671701	0.296547082872611
GO:0019887	protein kinase regulator activity	40/2287	255/18639	0.156862745098039	1.27842794310553	0.0608301708456638	0.296547082872611
GO:0019888	protein phosphatase regulator activity	19/2287	107/18639	0.177570093457944	1.44719237952016	0.0614969178105664	0.298666163102637
GO:0030955	potassium ion binding	4/2287	13/18639	0.307692307692308	2.50768558070701	0.0650901794081717	0.3071822228076
GO:0039706	co-receptor binding	4/2287	13/18639	0.307692307692308	2.50768558070701	0.0650901794081717	0.3071822228076
GO:0140333	glycerophospholipid flippase activity	4/2287	13/18639	0.307692307692308	2.50768558070701	0.0650901794081717	0.3071822228076
GO:0042056	chemoattractant activity	9/2287	42/18639	0.214285714285714	1.74642388656381	0.065116719568491	0.3071822228076
GO:0001091	RNA polymerase II general transcription initiation factor binding	6/2287	24/18639	0.25	2.03749453432444	0.0651598654440364	0.3071822228076
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	6/2287	24/18639	0.25	2.03749453432444	0.0651598654440364	0.3071822228076
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	6/2287	24/18639	0.25	2.03749453432444	0.0651598654440364	0.3071822228076
GO:0030215	semaphorin receptor binding	6/2287	24/18639	0.25	2.03749453432444	0.0651598654440364	0.3071822228076
GO:0045505	dynein intermediate chain binding	8/2287	36/18639	0.222222222222222	1.81110625273284	0.0664534257271895	0.308875173393996
GO:0015101	organic cation transmembrane transporter activity	15/2287	81/18639	0.185185185185185	1.5092552106107	0.0665437811053446	0.308875173393996
GO:0015215	nucleotide transmembrane transporter activity	7/2287	30/18639	0.233333333333333	1.90166156536948	0.066718957423101	0.308875173393996
GO:0016769	transferase activity, transferring nitrogenous groups	7/2287	30/18639	0.233333333333333	1.90166156536948	0.066718957423101	0.308875173393996
GO:0033612	receptor serine/threonine kinase binding	7/2287	30/18639	0.233333333333333	1.90166156536948	0.066718957423101	0.308875173393996
GO:0035591	signaling adaptor activity	22/2287	129/18639	0.170542635658915	1.38991875209729	0.0679911392779157	0.313440232193438
GO:0140789	histone phosphatase activity	23/2287	136/18639	0.169117647058824	1.37830512616065	0.0681921251081294	0.313440232193438
GO:0005004	GPI-linked ephrin receptor activity	10/2287	49/18639	0.204081632653061	1.66326084434648	0.0709988153816463	0.31508784619372
GO:0005008	hepatocyte growth factor receptor activity	10/2287	49/18639	0.204081632653061	1.66326084434648	0.0709988153816463	0.31508784619372
GO:0005009	insulin receptor activity	10/2287	49/18639	0.204081632653061	1.66326084434648	0.0709988153816463	0.31508784619372
GO:0005011	macrophage colony-stimulating factor receptor activity	10/2287	49/18639	0.204081632653061	1.66326084434648	0.0709988153816463	0.31508784619372
GO:0005018	platelet-derived growth factor alpha-receptor activity	10/2287	49/18639	0.204081632653061	1.66326084434648	0.0709988153816463	0.31508784619372
GO:0005020	stem cell factor receptor activity	10/2287	49/18639	0.204081632653061	1.66326084434648	0.0709988153816463	0.31508784619372
GO:0008288	boss receptor activity	10/2287	49/18639	0.204081632653061	1.66326084434648	0.0709988153816463	0.31508784619372
GO:0036332	placental growth factor receptor activity	10/2287	49/18639	0.204081632653061	1.66326084434648	0.0709988153816463	0.31508784619372
GO:0038062	protein tyrosine kinase collagen receptor activity	10/2287	49/18639	0.204081632653061	1.66326084434648	0.0709988153816463	0.31508784619372
GO:0060175	brain-derived neurotrophic factor receptor activity	10/2287	49/18639	0.204081632653061	1.66326084434648	0.0709988153816463	0.31508784619372
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	5/2287	19/18639	0.263157894736842	2.14473108876257	0.0740066122357095	0.323967720909381
GO:0031420	alkali metal ion binding	5/2287	19/18639	0.263157894736842	2.14473108876257	0.0740066122357095	0.323967720909381
GO:0097001	ceramide binding	5/2287	19/18639	0.263157894736842	2.14473108876257	0.0740066122357095	0.323967720909381
GO:1990380	K48-linked deubiquitinase activity	5/2287	19/18639	0.263157894736842	2.14473108876257	0.0740066122357095	0.323967720909381
GO:0042578	phosphoric ester hydrolase activity	54/2287	363/18639	0.148760330578512	1.21239344191206	0.0765555176354462	0.333989665073963
GO:0004709	MAP kinase kinase kinase activity	6/2287	25/18639	0.24	1.95599475295146	0.077207654880303	0.335612221027017
GO:0017147	Wnt-protein binding	7/2287	31/18639	0.225806451612903	1.84031764390595	0.0774489740831578	0.335612221027017
GO:0005007	fibroblast growth factor receptor activity	10/2287	50/18639	0.2	1.62999562745955	0.0794387929119684	0.341932195577603
GO:0032813	tumor necrosis factor receptor superfamily binding	10/2287	50/18639	0.2	1.62999562745955	0.0794387929119684	0.341932195577603
GO:0099106	ion channel regulator activity	26/2287	160/18639	0.1625	1.32437144731089	0.0815356523981668	0.344773848201378
GO:0008017	microtubule binding	42/2287	276/18639	0.152173913043478	1.2402140643714	0.0819889045691347	0.344773848201378
GO:0097110	scaffold protein binding	13/2287	70/18639	0.185714285714286	1.5135673683553	0.0820288600188092	0.344773848201378
GO:0005347	ATP transmembrane transporter activity	4/2287	14/18639	0.285714285714286	2.32856518208508	0.0825889865511908	0.344773848201378
GO:0044548	S100 protein binding	4/2287	14/18639	0.285714285714286	2.32856518208508	0.0825889865511908	0.344773848201378
GO:0071933	Arp2/3 complex binding	4/2287	14/18639	0.285714285714286	2.32856518208508	0.0825889865511908	0.344773848201378
GO:0098821	BMP receptor activity	4/2287	14/18639	0.285714285714286	2.32856518208508	0.0825889865511908	0.344773848201378
GO:1901474	azole transmembrane transporter activity	4/2287	14/18639	0.285714285714286	2.32856518208508	0.0825889865511908	0.344773848201378
GO:1990825	sequence-specific mRNA binding	4/2287	14/18639	0.285714285714286	2.32856518208508	0.0825889865511908	0.344773848201378
GO:0070851	growth factor receptor binding	23/2287	139/18639	0.165467625899281	1.3485575335097	0.0827778703140838	0.344773848201378
GO:0016247	channel regulator activity	27/2287	168/18639	0.160714285714286	1.30981791492286	0.0856821257289359	0.355719018752066
GO:0043531	ADP binding	8/2287	38/18639	0.210526315789474	1.71578487101006	0.0864778187966776	0.357868015406187
GO:0005021	vascular endothelial growth factor receptor activity	10/2287	51/18639	0.196078431372549	1.59803492888192	0.0884706825736104	0.363775618122162
GO:0005030	neurotrophin receptor activity	10/2287	51/18639	0.196078431372549	1.59803492888192	0.0884706825736104	0.363775618122162
GO:0120015	sterol transfer activity	7/2287	32/18639	0.21875	1.78280771753389	0.0891239333969749	0.364147674608564
GO:0016004	phospholipase activator activity	5/2287	20/18639	0.25	2.03749453432444	0.0891270532258724	0.364147674608564
GO:0004112	cyclic-nucleotide phosphodiesterase activity	6/2287	26/18639	0.230769230769231	1.88076418553025	0.09042193881058	0.36480575313234
GO:0050750	low-density lipoprotein particle receptor binding	6/2287	26/18639	0.230769230769231	1.88076418553025	0.09042193881058	0.36480575313234
GO:0051139	metal cation:proton antiporter activity	6/2287	26/18639	0.230769230769231	1.88076418553025	0.09042193881058	0.36480575313234
GO:0097602	cullin family protein binding	6/2287	26/18639	0.230769230769231	1.88076418553025	0.09042193881058	0.36480575313234
GO:0052689	carboxylic ester hydrolase activity	16/2287	92/18639	0.173913043478261	1.41738750213874	0.0939134953446598	0.377708339089304
GO:0043021	ribonucleoprotein complex binding	28/2287	177/18639	0.15819209039548	1.2892620782166	0.0946231045762998	0.379092215201771
GO:0008013	beta-catenin binding	18/2287	106/18639	0.169811320754717	1.3839585516166	0.0948466925368844	0.379092215201771
GO:0160215	deacylase activity	12/2287	65/18639	0.184615384615385	1.5046113484242	0.095526106104406	0.380005079849841
GO:0141108	transporter regulator activity	27/2287	170/18639	0.158823529411765	1.29440829239435	0.0956656145076524	0.380005079849841
GO:0016776	phosphotransferase activity, phosphate group as acceptor	8/2287	39/18639	0.205128205128205	1.671790387138	0.0976724505139911	0.386782904035405
GO:0030159	signaling receptor complex adaptor activity	10/2287	52/18639	0.192307692307692	1.56730348794188	0.0980945012761824	0.387262647676217
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	15/2287	86/18639	0.174418604651163	1.42150781464496	0.100457659653758	0.393694377192056
GO:0031490	chromatin DNA binding	21/2287	128/18639	0.1640625	1.33710578815042	0.100641375366112	0.393694377192056
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	21/2287	128/18639	0.1640625	1.33710578815042	0.100641375366112	0.393694377192056
GO:0019956	chemokine binding	7/2287	33/18639	0.212121212121212	1.72878324124498	0.101732393287864	0.395908543360966
GO:0015081	sodium ion transmembrane transporter activity	26/2287	164/18639	0.158536585365854	1.29206970469355	0.102090357545156	0.395908543360966
GO:0140776	protein-containing complex destabilizing activity	4/2287	15/18639	0.266666666666667	2.17332750327941	0.102130253609822	0.395908543360966
GO:0030291	protein serine/threonine kinase inhibitor activity	9/2287	46/18639	0.195652173913043	1.59456093990609	0.103848183950849	0.401359197431661
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	6/2287	27/18639	0.222222222222222	1.81110625273284	0.104777516744797	0.40373851512142
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	5/2287	21/18639	0.238095238095238	1.9404709850709	0.105711096706745	0.404911254349943
GO:0051428	peptide hormone receptor binding	5/2287	21/18639	0.238095238095238	1.9404709850709	0.105711096706745	0.404911254349943
GO:0017124	SH3 domain binding	19/2287	115/18639	0.165217391304348	1.34651812703181	0.108245320874111	0.411182763152776
GO:0017046	peptide hormone binding	10/2287	53/18639	0.188679245283019	1.53773172401845	0.108306881669612	0.411182763152776
GO:0140296	general transcription initiation factor binding	10/2287	53/18639	0.188679245283019	1.53773172401845	0.108306881669612	0.411182763152776
GO:0001094	TFIID-class transcription factor complex binding	3/2287	10/18639	0.3	2.44499344118933	0.114415989215841	0.419715442961665
GO:0004935	adrenergic receptor activity	3/2287	10/18639	0.3	2.44499344118933	0.114415989215841	0.419715442961665
GO:0015187	glycine transmembrane transporter activity	3/2287	10/18639	0.3	2.44499344118933	0.114415989215841	0.419715442961665
GO:0015643	toxic substance binding	3/2287	10/18639	0.3	2.44499344118933	0.114415989215841	0.419715442961665
GO:0016868	intramolecular phosphotransferase activity	3/2287	10/18639	0.3	2.44499344118933	0.114415989215841	0.419715442961665
GO:0042975	peroxisome proliferator activated receptor binding	3/2287	10/18639	0.3	2.44499344118933	0.114415989215841	0.419715442961665
GO:0070513	death domain binding	3/2287	10/18639	0.3	2.44499344118933	0.114415989215841	0.419715442961665
GO:0046873	metal ion transmembrane transporter activity	64/2287	450/18639	0.142222222222222	1.15910800174902	0.115422061829028	0.419715442961665
GO:0030971	receptor tyrosine kinase binding	14/2287	81/18639	0.172839506172839	1.40863819656998	0.116098444206956	0.419715442961665
GO:0033192	calmodulin-dependent protein phosphatase activity	14/2287	81/18639	0.172839506172839	1.40863819656998	0.116098444206956	0.419715442961665
GO:0140791	histone H2AXS140 phosphatase activity	14/2287	81/18639	0.172839506172839	1.40863819656998	0.116098444206956	0.419715442961665
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	14/2287	81/18639	0.172839506172839	1.40863819656998	0.116098444206956	0.419715442961665
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	14/2287	81/18639	0.172839506172839	1.40863819656998	0.116098444206956	0.419715442961665
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	14/2287	81/18639	0.172839506172839	1.40863819656998	0.116098444206956	0.419715442961665
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	14/2287	81/18639	0.172839506172839	1.40863819656998	0.116098444206956	0.419715442961665
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	14/2287	81/18639	0.172839506172839	1.40863819656998	0.116098444206956	0.419715442961665
GO:1990439	MAP kinase serine/threonine phosphatase activity	14/2287	81/18639	0.172839506172839	1.40863819656998	0.116098444206956	0.419715442961665
GO:0050698	proteoglycan sulfotransferase activity	6/2287	28/18639	0.214285714285714	1.74642388656381	0.12023652038756	0.431393635602748
GO:0051959	dynein light intermediate chain binding	6/2287	28/18639	0.214285714285714	1.74642388656381	0.12023652038756	0.431393635602748
GO:0005262	calcium channel activity	21/2287	131/18639	0.16030534351145	1.30648504491033	0.120422344376114	0.431393635602748
GO:0015026	coreceptor activity	11/2287	61/18639	0.180327868852459	1.46966818869304	0.121765457722202	0.431393635602748
GO:0015175	neutral L-amino acid transmembrane transporter activity	8/2287	41/18639	0.195121951219512	1.59023963654591	0.122377338782494	0.431393635602748
GO:1990782	protein tyrosine kinase binding	19/2287	117/18639	0.162393162393162	1.32350072315092	0.122656514782512	0.431393635602748
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	4/2287	16/18639	0.25	2.03749453432444	0.123562534873587	0.431393635602748
GO:0008142	oxysterol binding	4/2287	16/18639	0.25	2.03749453432444	0.123562534873587	0.431393635602748
GO:0055102	lipase inhibitor activity	4/2287	16/18639	0.25	2.03749453432444	0.123562534873587	0.431393635602748
GO:0061809	NAD+ nucleosidase activity, cyclic ADP-ribose generating	4/2287	16/18639	0.25	2.03749453432444	0.123562534873587	0.431393635602748
GO:0099507	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	4/2287	16/18639	0.25	2.03749453432444	0.123562534873587	0.431393635602748
GO:0140328	floppase activity	4/2287	16/18639	0.25	2.03749453432444	0.123562534873587	0.431393635602748
GO:0030021	extracellular matrix structural constituent conferring compression resistance	5/2287	22/18639	0.227272727272727	1.85226775847677	0.123686287130858	0.431393635602748
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	14/2287	82/18639	0.170731707317073	1.39145968197767	0.125051272256803	0.433803200524274
GO:0033549	MAP kinase phosphatase activity	14/2287	82/18639	0.170731707317073	1.39145968197767	0.125051272256803	0.433803200524274
GO:0016879	ligase activity, forming carbon-nitrogen bonds	9/2287	48/18639	0.1875	1.52812090074333	0.127223997617653	0.440153991757849
GO:0098632	cell-cell adhesion mediator activity	10/2287	55/18639	0.181818181818182	1.48181420678141	0.130467195967427	0.448960644946735
GO:0140313	molecular sequestering activity	10/2287	55/18639	0.181818181818182	1.48181420678141	0.130467195967427	0.448960644946735
GO:0015179	L-amino acid transmembrane transporter activity	11/2287	62/18639	0.17741935483871	1.44596386306896	0.132547196269588	0.454901977597227
GO:0002039	p53 binding	12/2287	69/18639	0.173913043478261	1.41738750213874	0.133763458818962	0.457855243351073
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	14/2287	83/18639	0.168674698795181	1.37469510749601	0.134387648202303	0.458771626621656
GO:0000295	adenine nucleotide transmembrane transporter activity	5/2287	23/18639	0.217391304347826	1.77173437767343	0.142963006087586	0.466202293679325
GO:0004022	alcohol dehydrogenase (NAD+) activity	5/2287	23/18639	0.217391304347826	1.77173437767343	0.142963006087586	0.466202293679325
GO:0005212	structural constituent of eye lens	5/2287	23/18639	0.217391304347826	1.77173437767343	0.142963006087586	0.466202293679325
GO:0031681	G-protein beta-subunit binding	5/2287	23/18639	0.217391304347826	1.77173437767343	0.142963006087586	0.466202293679325
GO:0043274	phospholipase binding	5/2287	23/18639	0.217391304347826	1.77173437767343	0.142963006087586	0.466202293679325
GO:0001161	intronic transcription regulatory region sequence-specific DNA binding	3/2287	11/18639	0.272727272727273	2.22272131017212	0.143583370167044	0.466202293679325
GO:0004117	calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity	3/2287	11/18639	0.272727272727273	2.22272131017212	0.143583370167044	0.466202293679325
GO:0016176	superoxide-generating NADPH oxidase activator activity	3/2287	11/18639	0.272727272727273	2.22272131017212	0.143583370167044	0.466202293679325
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	3/2287	11/18639	0.272727272727273	2.22272131017212	0.143583370167044	0.466202293679325
GO:0032050	clathrin heavy chain binding	3/2287	11/18639	0.272727272727273	2.22272131017212	0.143583370167044	0.466202293679325
GO:0034056	estrogen response element binding	3/2287	11/18639	0.272727272727273	2.22272131017212	0.143583370167044	0.466202293679325
GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	3/2287	11/18639	0.272727272727273	2.22272131017212	0.143583370167044	0.466202293679325
GO:0048101	calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity	3/2287	11/18639	0.272727272727273	2.22272131017212	0.143583370167044	0.466202293679325
GO:0070990	snRNP binding	3/2287	11/18639	0.272727272727273	2.22272131017212	0.143583370167044	0.466202293679325
GO:0140031	phosphorylation-dependent protein binding	3/2287	11/18639	0.272727272727273	2.22272131017212	0.143583370167044	0.466202293679325
GO:0017018	myosin phosphatase activity	14/2287	84/18639	0.166666666666667	1.35832968954963	0.144101879556204	0.466202293679325
GO:0016782	transferase activity, transferring sulphur-containing groups	12/2287	70/18639	0.171428571428571	1.39713910925105	0.144467168915544	0.466202293679325
GO:0004869	cysteine-type endopeptidase inhibitor activity	7/2287	36/18639	0.194444444444444	1.58471797114123	0.144918819082034	0.466202293679325
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	7/2287	36/18639	0.194444444444444	1.58471797114123	0.144918819082034	0.466202293679325
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	7/2287	36/18639	0.194444444444444	1.58471797114123	0.144918819082034	0.466202293679325
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	7/2287	36/18639	0.194444444444444	1.58471797114123	0.144918819082034	0.466202293679325
GO:0004550	nucleoside diphosphate kinase activity	4/2287	17/18639	0.235294117647059	1.9176419146583	0.146707015493494	0.466202293679325
GO:0008484	sulfuric ester hydrolase activity	4/2287	17/18639	0.235294117647059	1.9176419146583	0.146707015493494	0.466202293679325
GO:0009881	photoreceptor activity	4/2287	17/18639	0.235294117647059	1.9176419146583	0.146707015493494	0.466202293679325
GO:0017110	nucleoside diphosphate phosphatase activity	4/2287	17/18639	0.235294117647059	1.9176419146583	0.146707015493494	0.466202293679325
GO:0038191	neuropilin binding	4/2287	17/18639	0.235294117647059	1.9176419146583	0.146707015493494	0.466202293679325
GO:0051787	misfolded protein binding	4/2287	17/18639	0.235294117647059	1.9176419146583	0.146707015493494	0.466202293679325
GO:0070403	NAD+ binding	4/2287	17/18639	0.235294117647059	1.9176419146583	0.146707015493494	0.466202293679325
GO:0005245	voltage-gated calcium channel activity	8/2287	43/18639	0.186046511627907	1.51627500228796	0.150036831954685	0.475609366319407
GO:0019842	vitamin binding	23/2287	150/18639	0.153333333333333	1.24966331438566	0.153075050000037	0.484048131081199
GO:0140030	modification-dependent protein binding	26/2287	173/18639	0.15028901734104	1.22485220560545	0.159555645337517	0.503304204777904
GO:0019213	deacetylase activity	7/2287	37/18639	0.189189189189189	1.54188775570498	0.16098349379421	0.505573332410569
GO:0043130	ubiquitin binding	16/2287	100/18639	0.16	1.30399650196764	0.161060657566692	0.505573332410569
GO:0005540	hyaluronic acid binding	5/2287	24/18639	0.208333333333333	1.69791211193704	0.163437516783257	0.509307709685354
GO:0035035	histone acetyltransferase binding	5/2287	24/18639	0.208333333333333	1.69791211193704	0.163437516783257	0.509307709685354
GO:0060229	lipase activator activity	5/2287	24/18639	0.208333333333333	1.69791211193704	0.163437516783257	0.509307709685354
GO:0005272	sodium channel activity	9/2287	51/18639	0.176470588235294	1.43823143599372	0.166999015340691	0.518540676797084
GO:0004843	cysteine-type deubiquitinase activity	17/2287	108/18639	0.157407407407407	1.28286692901909	0.168459607875987	0.518540676797084
GO:0004706	JUN kinase kinase kinase activity	4/2287	18/18639	0.222222222222222	1.81110625273284	0.171365562106667	0.518540676797084
GO:0008308	voltage-gated monoatomic anion channel activity	4/2287	18/18639	0.222222222222222	1.81110625273284	0.171365562106667	0.518540676797084
GO:0008525	phosphatidylcholine transporter activity	4/2287	18/18639	0.222222222222222	1.81110625273284	0.171365562106667	0.518540676797084
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	4/2287	18/18639	0.222222222222222	1.81110625273284	0.171365562106667	0.518540676797084
GO:0017128	phospholipid scramblase activity	4/2287	18/18639	0.222222222222222	1.81110625273284	0.171365562106667	0.518540676797084
GO:0035615	clathrin adaptor activity	4/2287	18/18639	0.222222222222222	1.81110625273284	0.171365562106667	0.518540676797084
GO:0070064	proline-rich region binding	4/2287	18/18639	0.222222222222222	1.81110625273284	0.171365562106667	0.518540676797084
GO:0070628	proteasome binding	4/2287	18/18639	0.222222222222222	1.81110625273284	0.171365562106667	0.518540676797084
GO:0098641	cadherin binding involved in cell-cell adhesion	4/2287	18/18639	0.222222222222222	1.81110625273284	0.171365562106667	0.518540676797084
GO:1901611	phosphatidylglycerol binding	4/2287	18/18639	0.222222222222222	1.81110625273284	0.171365562106667	0.518540676797084
GO:0008194	UDP-glycosyltransferase activity	22/2287	145/18639	0.151724137931034	1.23654840703828	0.171820992034857	0.518540676797084
GO:0004721	phosphoprotein phosphatase activity	26/2287	175/18639	0.148571428571429	1.21085389468424	0.174394639777455	0.518540676797084
GO:0005078	MAP-kinase scaffold activity	3/2287	12/18639	0.25	2.03749453432444	0.174861424809584	0.518540676797084
GO:0015368	calcium:monoatomic cation antiporter activity	3/2287	12/18639	0.25	2.03749453432444	0.174861424809584	0.518540676797084
GO:0016208	AMP binding	3/2287	12/18639	0.25	2.03749453432444	0.174861424809584	0.518540676797084
GO:0035197	siRNA binding	3/2287	12/18639	0.25	2.03749453432444	0.174861424809584	0.518540676797084
GO:0035251	UDP-glucosyltransferase activity	3/2287	12/18639	0.25	2.03749453432444	0.174861424809584	0.518540676797084
GO:0035497	cAMP response element binding	3/2287	12/18639	0.25	2.03749453432444	0.174861424809584	0.518540676797084
GO:1902282	voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	3/2287	12/18639	0.25	2.03749453432444	0.174861424809584	0.518540676797084
GO:0031593	polyubiquitin modification-dependent protein binding	10/2287	59/18639	0.169491525423729	1.38135222666064	0.181342511963214	0.535293148845543
GO:0070888	E-box binding	10/2287	59/18639	0.169491525423729	1.38135222666064	0.181342511963214	0.535293148845543
GO:0008139	nuclear localization sequence binding	5/2287	25/18639	0.2	1.62999562745955	0.184994982258995	0.541110323107561
GO:0008483	transaminase activity	5/2287	25/18639	0.2	1.62999562745955	0.184994982258995	0.541110323107561
GO:0019211	phosphatase activator activity	5/2287	25/18639	0.2	1.62999562745955	0.184994982258995	0.541110323107561
GO:0047617	fatty acyl-CoA hydrolase activity	5/2287	25/18639	0.2	1.62999562745955	0.184994982258995	0.541110323107561
GO:0008237	metallopeptidase activity	27/2287	184/18639	0.146739130434783	1.19592070492956	0.186051792309039	0.542967475514134
GO:0051059	NF-kappaB binding	6/2287	32/18639	0.1875	1.52812090074333	0.191976021599418	0.556471035582097
GO:0071813	lipoprotein particle binding	6/2287	32/18639	0.1875	1.52812090074333	0.191976021599418	0.556471035582097
GO:0071814	protein-lipid complex binding	6/2287	32/18639	0.1875	1.52812090074333	0.191976021599418	0.556471035582097
GO:0016500	protein-hormone receptor activity	11/2287	67/18639	0.164179104477612	1.33805611209366	0.193639331365597	0.560031054983197
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	7/2287	39/18639	0.179487179487179	1.46281658874575	0.195336866441522	0.563106585425705
GO:0008146	sulfotransferase activity	9/2287	53/18639	0.169811320754717	1.3839585516166	0.196376028522233	0.563106585425705
GO:0051018	protein kinase A binding	9/2287	53/18639	0.169811320754717	1.3839585516166	0.196376028522233	0.563106585425705
GO:0005229	intracellularly calcium-gated chloride channel activity	4/2287	19/18639	0.210526315789474	1.71578487101006	0.197327948738922	0.563106585425705
GO:0005346	purine ribonucleotide transmembrane transporter activity	4/2287	19/18639	0.210526315789474	1.71578487101006	0.197327948738922	0.563106585425705
GO:0141147	intracellularly calcium-gated channel activity	4/2287	19/18639	0.210526315789474	1.71578487101006	0.197327948738922	0.563106585425705
GO:0008514	organic anion transmembrane transporter activity	38/2287	269/18639	0.141263940520446	1.15129802683017	0.198167814834464	0.5642521630353
GO:0019003	GDP binding	12/2287	75/18639	0.16	1.30399650196764	0.204307104271253	0.568998577828553
GO:0005112	Notch binding	5/2287	26/18639	0.192307692307692	1.56730348794188	0.207512373556237	0.568998577828553
GO:0008066	glutamate receptor activity	5/2287	26/18639	0.192307692307692	1.56730348794188	0.207512373556237	0.568998577828553
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	5/2287	26/18639	0.192307692307692	1.56730348794188	0.207512373556237	0.568998577828553
GO:0008157	protein phosphatase 1 binding	5/2287	26/18639	0.192307692307692	1.56730348794188	0.207512373556237	0.568998577828553
GO:0015216	purine nucleotide transmembrane transporter activity	5/2287	26/18639	0.192307692307692	1.56730348794188	0.207512373556237	0.568998577828553
GO:0016289	acyl-CoA hydrolase activity	5/2287	26/18639	0.192307692307692	1.56730348794188	0.207512373556237	0.568998577828553
GO:0030507	spectrin binding	5/2287	26/18639	0.192307692307692	1.56730348794188	0.207512373556237	0.568998577828553
GO:0070006	metalloaminopeptidase activity	5/2287	26/18639	0.192307692307692	1.56730348794188	0.207512373556237	0.568998577828553
GO:0070412	R-SMAD binding	5/2287	26/18639	0.192307692307692	1.56730348794188	0.207512373556237	0.568998577828553
GO:0120014	phospholipid transfer activity	5/2287	26/18639	0.192307692307692	1.56730348794188	0.207512373556237	0.568998577828553
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	3/2287	13/18639	0.230769230769231	1.88076418553025	0.207792798430008	0.568998577828553
GO:0008035	high-density lipoprotein particle binding	3/2287	13/18639	0.230769230769231	1.88076418553025	0.207792798430008	0.568998577828553
GO:0019855	calcium channel inhibitor activity	3/2287	13/18639	0.230769230769231	1.88076418553025	0.207792798430008	0.568998577828553
GO:0061459	L-arginine transmembrane transporter activity	3/2287	13/18639	0.230769230769231	1.88076418553025	0.207792798430008	0.568998577828553
GO:0070700	BMP receptor binding	3/2287	13/18639	0.230769230769231	1.88076418553025	0.207792798430008	0.568998577828553
GO:0140410	monoatomic cation:bicarbonate symporter activity	3/2287	13/18639	0.230769230769231	1.88076418553025	0.207792798430008	0.568998577828553
GO:1901338	catecholamine binding	3/2287	13/18639	0.230769230769231	1.88076418553025	0.207792798430008	0.568998577828553
GO:0019905	syntaxin binding	10/2287	61/18639	0.163934426229508	1.33606198972095	0.209733458922617	0.573093336801292
GO:0019783	ubiquitin-like protein peptidase activity	19/2287	127/18639	0.149606299212598	1.21928806778471	0.210494455280516	0.573954160902594
GO:0005096	GTPase activator activity	38/2287	271/18639	0.140221402214022	1.14280136242552	0.211556462394194	0.574490142095905
GO:0050661	NADP binding	9/2287	54/18639	0.166666666666667	1.35832968954963	0.211831012347397	0.574490142095905
GO:0140311	protein sequestering activity	6/2287	33/18639	0.181818181818182	1.48181420678141	0.212030161224207	0.574490142095905
GO:0043495	protein-membrane adaptor activity	8/2287	47/18639	0.170212765957447	1.38723032124217	0.213222436868663	0.576506882878087
GO:0015297	antiporter activity	20/2287	135/18639	0.148148148148148	1.20740416848856	0.215824515071971	0.582318974628147
GO:0017022	myosin binding	12/2287	76/18639	0.157894736842105	1.28683865325754	0.217428497114736	0.585419405411433
GO:0005125	cytokine activity	33/2287	234/18639	0.141025641025641	1.14935589115738	0.22060475312134	0.592731351288442
GO:0072341	modified amino acid binding	14/2287	91/18639	0.153846153846154	1.2538427903535	0.221922832086576	0.595030593532132
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	26/2287	181/18639	0.143646408839779	1.17071509154554	0.223086020236446	0.596705297501336
GO:0030742	GTP-dependent protein binding	4/2287	20/18639	0.2	1.62999562745955	0.224378172617184	0.596705297501336
GO:0052745	inositol phosphate phosphatase activity	4/2287	20/18639	0.2	1.62999562745955	0.224378172617184	0.596705297501336
GO:0000149	SNARE binding	16/2287	106/18639	0.150943396226415	1.23018537921476	0.224401992222725	0.596705297501336
GO:0008374	O-acyltransferase activity	9/2287	55/18639	0.163636363636364	1.33363278610327	0.2277500199	0.604359331157318
GO:0001671	ATPase activator activity	5/2287	27/18639	0.185185185185185	1.5092552106107	0.230861204649746	0.607604029415589
GO:0004364	glutathione transferase activity	5/2287	27/18639	0.185185185185185	1.5092552106107	0.230861204649746	0.607604029415589
GO:0005385	zinc ion transmembrane transporter activity	5/2287	27/18639	0.185185185185185	1.5092552106107	0.230861204649746	0.607604029415589
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	5/2287	27/18639	0.185185185185185	1.5092552106107	0.230861204649746	0.607604029415589
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	7/2287	41/18639	0.170731707317073	1.39145968197767	0.232277544782703	0.608886602504044
GO:0015020	glucuronosyltransferase activity	6/2287	34/18639	0.176470588235294	1.43823143599372	0.232767838719495	0.608886602504044
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	6/2287	34/18639	0.176470588235294	1.43823143599372	0.232767838719495	0.608886602504044
GO:0017171	serine hydrolase activity	28/2287	198/18639	0.141414141414141	1.15252216082999	0.238278746821339	0.615367331124277
GO:0005507	copper ion binding	10/2287	63/18639	0.158730158730159	1.2936473233806	0.239812744641879	0.615367331124277
GO:0101005	deubiquitinase activity	17/2287	115/18639	0.147826086956522	1.20477937681793	0.241854253322127	0.615367331124277
GO:0004065	arylsulfatase activity	3/2287	14/18639	0.214285714285714	1.74642388656381	0.241939292578776	0.615367331124277
GO:0005545	1-phosphatidylinositol binding	3/2287	14/18639	0.214285714285714	1.74642388656381	0.241939292578776	0.615367331124277
GO:0008331	high voltage-gated calcium channel activity	3/2287	14/18639	0.214285714285714	1.74642388656381	0.241939292578776	0.615367331124277
GO:0008474	palmitoyl-(protein) hydrolase activity	3/2287	14/18639	0.214285714285714	1.74642388656381	0.241939292578776	0.615367331124277
GO:0019992	diacylglycerol binding	3/2287	14/18639	0.214285714285714	1.74642388656381	0.241939292578776	0.615367331124277
GO:0030983	mismatched DNA binding	3/2287	14/18639	0.214285714285714	1.74642388656381	0.241939292578776	0.615367331124277
GO:0032036	myosin heavy chain binding	3/2287	14/18639	0.214285714285714	1.74642388656381	0.241939292578776	0.615367331124277
GO:0042813	Wnt receptor activity	3/2287	14/18639	0.214285714285714	1.74642388656381	0.241939292578776	0.615367331124277
GO:0046030	inositol trisphosphate phosphatase activity	3/2287	14/18639	0.214285714285714	1.74642388656381	0.241939292578776	0.615367331124277
GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization	3/2287	14/18639	0.214285714285714	1.74642388656381	0.241939292578776	0.615367331124277
GO:0098599	palmitoyl hydrolase activity	3/2287	14/18639	0.214285714285714	1.74642388656381	0.241939292578776	0.615367331124277
GO:0003774	cytoskeletal motor activity	22/2287	153/18639	0.143790849673203	1.17189228118007	0.244643297186843	0.621017600551216
GO:0051213	dioxygenase activity	14/2287	93/18639	0.150537634408602	1.22687842927063	0.246943803227695	0.625623375500086
GO:0016763	pentosyltransferase activity	8/2287	49/18639	0.163265306122449	1.33060867547719	0.248089922006301	0.626062214945313
GO:0035254	glutamate receptor binding	8/2287	49/18639	0.163265306122449	1.33060867547719	0.248089922006301	0.626062214945313
GO:0016859	cis-trans isomerase activity	7/2287	42/18639	0.166666666666667	1.35832968954963	0.251562968607969	0.626853071255771
GO:0035198	miRNA binding	7/2287	42/18639	0.166666666666667	1.35832968954963	0.251562968607969	0.626853071255771
GO:0009931	calcium-dependent protein serine/threonine kinase activity	4/2287	21/18639	0.19047619047619	1.55237678805672	0.252299837537288	0.626853071255771
GO:0009975	cyclase activity	4/2287	21/18639	0.19047619047619	1.55237678805672	0.252299837537288	0.626853071255771
GO:0015174	basic amino acid transmembrane transporter activity	4/2287	21/18639	0.19047619047619	1.55237678805672	0.252299837537288	0.626853071255771
GO:0035613	RNA stem-loop binding	4/2287	21/18639	0.19047619047619	1.55237678805672	0.252299837537288	0.626853071255771
GO:0070182	DNA polymerase binding	4/2287	21/18639	0.19047619047619	1.55237678805672	0.252299837537288	0.626853071255771
GO:0140312	cargo adaptor activity	4/2287	21/18639	0.19047619047619	1.55237678805672	0.252299837537288	0.626853071255771
GO:0043015	gamma-tubulin binding	6/2287	35/18639	0.171428571428571	1.39713910925105	0.254100151710486	0.627283428553021
GO:0061631	ubiquitin conjugating enzyme activity	6/2287	35/18639	0.171428571428571	1.39713910925105	0.254100151710486	0.627283428553021
GO:0046625	sphingolipid binding	5/2287	28/18639	0.178571428571429	1.45535323880317	0.254910049054569	0.627283428553021
GO:0051119	sugar transmembrane transporter activity	5/2287	28/18639	0.178571428571429	1.45535323880317	0.254910049054569	0.627283428553021
GO:0097718	disordered domain specific binding	5/2287	28/18639	0.178571428571429	1.45535323880317	0.254910049054569	0.627283428553021
GO:0004601	peroxidase activity	9/2287	57/18639	0.157894736842105	1.28683865325754	0.260826904802341	0.640618752825597
GO:0030695	GTPase regulator activity	65/2287	489/18639	0.132924335378323	1.08333042724817	0.261557426868175	0.641189349293983
GO:0060589	nucleoside-triphosphatase regulator activity	65/2287	490/18639	0.13265306122449	1.08111954882521	0.267250102370402	0.653899014735184
GO:0015291	secondary active transmembrane transporter activity	39/2287	287/18639	0.13588850174216	1.10748831830876	0.270985225851348	0.661779858957656
GO:0044390	ubiquitin-like protein conjugating enzyme binding	6/2287	36/18639	0.166666666666667	1.35832968954963	0.275936418236177	0.662075762503166
GO:0004467	long-chain fatty acid-CoA ligase activity	3/2287	15/18639	0.2	1.62999562745955	0.276891552321014	0.662075762503166
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	3/2287	15/18639	0.2	1.62999562745955	0.276891552321014	0.662075762503166
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	3/2287	15/18639	0.2	1.62999562745955	0.276891552321014	0.662075762503166
GO:0008242	omega peptidase activity	3/2287	15/18639	0.2	1.62999562745955	0.276891552321014	0.662075762503166
GO:0016846	carbon-sulfur lyase activity	3/2287	15/18639	0.2	1.62999562745955	0.276891552321014	0.662075762503166
GO:0030553	cGMP binding	3/2287	15/18639	0.2	1.62999562745955	0.276891552321014	0.662075762503166
GO:0047372	monoacylglycerol lipase activity	3/2287	15/18639	0.2	1.62999562745955	0.276891552321014	0.662075762503166
GO:0061578	K63-linked deubiquitinase activity	3/2287	15/18639	0.2	1.62999562745955	0.276891552321014	0.662075762503166
GO:0120283	protein serine/threonine kinase binding	3/2287	15/18639	0.2	1.62999562745955	0.276891552321014	0.662075762503166
GO:0061980	regulatory RNA binding	9/2287	58/18639	0.155172413793103	1.26465177992552	0.277904287621135	0.662075762503166
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	5/2287	29/18639	0.172413793103448	1.40516864436168	0.27952680851586	0.662075762503166
GO:0043539	protein serine/threonine kinase activator activity	11/2287	73/18639	0.150684931506849	1.22807889740103	0.280161380525986	0.662075762503166
GO:0004407	histone deacetylase activity	4/2287	22/18639	0.181818181818182	1.48181420678141	0.280880626516495	0.662075762503166
GO:0008093	cytoskeletal anchor activity	4/2287	22/18639	0.181818181818182	1.48181420678141	0.280880626516495	0.662075762503166
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	4/2287	22/18639	0.181818181818182	1.48181420678141	0.280880626516495	0.662075762503166
GO:0033558	protein lysine deacetylase activity	4/2287	22/18639	0.181818181818182	1.48181420678141	0.280880626516495	0.662075762503166
GO:0034062	5'-3' RNA polymerase activity	4/2287	22/18639	0.181818181818182	1.48181420678141	0.280880626516495	0.662075762503166
GO:0097747	RNA polymerase activity	4/2287	22/18639	0.181818181818182	1.48181420678141	0.280880626516495	0.662075762503166
GO:0005048	signal sequence binding	8/2287	51/18639	0.156862745098039	1.27842794310553	0.28462684034431	0.669679604247032
GO:0140597	protein carrier chaperone	26/2287	188/18639	0.138297872340426	1.12712463600927	0.286811017170159	0.673587188135027
GO:0016248	channel inhibitor activity	7/2287	44/18639	0.159090909090909	1.29658743093374	0.291433722230438	0.679484058895966
GO:0016790	thiolester hydrolase activity	7/2287	44/18639	0.159090909090909	1.29658743093374	0.291433722230438	0.679484058895966
GO:0019205	nucleobase-containing compound kinase activity	7/2287	44/18639	0.159090909090909	1.29658743093374	0.291433722230438	0.679484058895966
GO:0030547	signaling receptor inhibitor activity	7/2287	44/18639	0.159090909090909	1.29658743093374	0.291433722230438	0.679484058895966
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	9/2287	59/18639	0.152542372881356	1.24321700399458	0.295285407239561	0.686788368815536
GO:0035064	methylated histone binding	11/2287	74/18639	0.148648648648649	1.21148323662534	0.295633843297441	0.686788368815536
GO:0016757	glycosyltransferase activity	36/2287	267/18639	0.134831460674157	1.09887345671431	0.297576599336113	0.690056006028068
GO:0016758	hexosyltransferase activity	27/2287	197/18639	0.137055837563452	1.11700207973117	0.298735832531633	0.691498231057934
GO:0016887	ATP hydrolysis activity	55/2287	417/18639	0.13189448441247	1.07493716439179	0.302660084486839	0.69932410903871
GO:0001965	G-protein alpha-subunit binding	5/2287	30/18639	0.166666666666667	1.35832968954963	0.304580717180094	0.702500686399249
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	31/2287	229/18639	0.135371179039301	1.10327214959053	0.306581426425103	0.702619136396908
GO:0004602	glutathione peroxidase activity	4/2287	23/18639	0.173913043478261	1.41738750213874	0.309915915027844	0.702619136396908
GO:0016849	phosphorus-oxygen lyase activity	4/2287	23/18639	0.173913043478261	1.41738750213874	0.309915915027844	0.702619136396908
GO:0099186	structural constituent of postsynapse	4/2287	23/18639	0.173913043478261	1.41738750213874	0.309915915027844	0.702619136396908
GO:0022832	voltage-gated channel activity	24/2287	175/18639	0.137142857142857	1.11771128740084	0.311555683352538	0.702619136396908
GO:0004715	non-membrane spanning protein tyrosine kinase activity	7/2287	45/18639	0.155555555555556	1.26777437691299	0.311883767117285	0.702619136396908
GO:0008009	chemokine activity	7/2287	45/18639	0.155555555555556	1.26777437691299	0.311883767117285	0.702619136396908
GO:0046915	transition metal ion transmembrane transporter activity	7/2287	45/18639	0.155555555555556	1.26777437691299	0.311883767117285	0.702619136396908
GO:0141110	transporter inhibitor activity	7/2287	45/18639	0.155555555555556	1.26777437691299	0.311883767117285	0.702619136396908
GO:0004198	calcium-dependent cysteine-type endopeptidase activity	3/2287	16/18639	0.1875	1.52812090074333	0.312275171731959	0.702619136396908
GO:0004708	MAP kinase kinase activity	3/2287	16/18639	0.1875	1.52812090074333	0.312275171731959	0.702619136396908
GO:0022858	alanine transmembrane transporter activity	3/2287	16/18639	0.1875	1.52812090074333	0.312275171731959	0.702619136396908
GO:0034450	ubiquitin-ubiquitin ligase activity	3/2287	16/18639	0.1875	1.52812090074333	0.312275171731959	0.702619136396908
GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	3/2287	16/18639	0.1875	1.52812090074333	0.312275171731959	0.702619136396908
GO:0003697	single-stranded DNA binding	17/2287	121/18639	0.140495867768595	1.14503825069473	0.313273725082572	0.703635749007453
GO:0000146	microfilament motor activity	6/2287	38/18639	0.157894736842105	1.28683865325754	0.320756249253392	0.719186921235392
GO:0016860	intramolecular oxidoreductase activity	8/2287	53/18639	0.150943396226415	1.23018537921476	0.322416541630836	0.721652328832844
GO:0005261	monoatomic cation channel activity	45/2287	341/18639	0.131964809384164	1.07551031137361	0.323074879322408	0.721870433486004
GO:0140034	methylation-dependent protein binding	11/2287	76/18639	0.144736842105263	1.17960209881941	0.327221756167278	0.729868977794257
GO:0008327	methyl-CpG binding	5/2287	31/18639	0.161290322580645	1.31451260278996	0.329944075279831	0.729942305134535
GO:0047499	calcium-independent phospholipase A2 activity	5/2287	31/18639	0.161290322580645	1.31451260278996	0.329944075279831	0.729942305134535
GO:0072349	modified amino acid transmembrane transporter activity	5/2287	31/18639	0.161290322580645	1.31451260278996	0.329944075279831	0.729942305134535
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	9/2287	61/18639	0.147540983606557	1.20245579074885	0.330788229265019	0.729942305134535
GO:0004180	carboxypeptidase activity	7/2287	46/18639	0.152173913043478	1.2402140643714	0.332586601299777	0.729942305134535
GO:0030276	clathrin binding	7/2287	46/18639	0.152173913043478	1.2402140643714	0.332586601299777	0.729942305134535
GO:0043178	alcohol binding	13/2287	92/18639	0.141304347826087	1.15162734548773	0.337437157733177	0.729942305134535
GO:0005315	phosphate transmembrane transporter activity	4/2287	24/18639	0.166666666666667	1.35832968954963	0.339211594676762	0.729942305134535
GO:0015149	hexose transmembrane transporter activity	4/2287	24/18639	0.166666666666667	1.35832968954963	0.339211594676762	0.729942305134535
GO:0048027	mRNA 5'-UTR binding	4/2287	24/18639	0.166666666666667	1.35832968954963	0.339211594676762	0.729942305134535
GO:0055056	D-glucose transmembrane transporter activity	4/2287	24/18639	0.166666666666667	1.35832968954963	0.339211594676762	0.729942305134535
GO:0070300	phosphatidic acid binding	4/2287	24/18639	0.166666666666667	1.35832968954963	0.339211594676762	0.729942305134535
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	8/2287	54/18639	0.148148148148148	1.20740416848856	0.341648807593173	0.729942305134535
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	6/2287	39/18639	0.153846153846154	1.2538427903535	0.343559773401004	0.729942305134535
GO:0008236	serine-type peptidase activity	26/2287	194/18639	0.134020618556701	1.09226511118424	0.345950410425577	0.729942305134535
GO:0008569	minus-end-directed microtubule motor activity	3/2287	17/18639	0.176470588235294	1.43823143599372	0.347754062354487	0.729942305134535
GO:0015347	sodium-independent organic anion transmembrane transporter activity	3/2287	17/18639	0.176470588235294	1.43823143599372	0.347754062354487	0.729942305134535
GO:0030169	low-density lipoprotein particle binding	3/2287	17/18639	0.176470588235294	1.43823143599372	0.347754062354487	0.729942305134535
GO:0032183	SUMO binding	3/2287	17/18639	0.176470588235294	1.43823143599372	0.347754062354487	0.729942305134535
GO:0005216	monoatomic ion channel activity	58/2287	448/18639	0.129464285714286	1.0551310981323	0.35054901000649	0.729942305134535
GO:0051219	phosphoprotein binding	13/2287	93/18639	0.139784946236559	1.1392442557513	0.352142327840318	0.729942305134535
GO:0003680	minor groove of adenine-thymine-rich DNA binding	2/2287	10/18639	0.2	1.62999562745955	0.352209923456524	0.729942305134535
GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	2/2287	10/18639	0.2	1.62999562745955	0.352209923456524	0.729942305134535
GO:0004445	inositol-polyphosphate 5-phosphatase activity	2/2287	10/18639	0.2	1.62999562745955	0.352209923456524	0.729942305134535
GO:0004955	prostaglandin receptor activity	2/2287	10/18639	0.2	1.62999562745955	0.352209923456524	0.729942305134535
GO:0005131	growth hormone receptor binding	2/2287	10/18639	0.2	1.62999562745955	0.352209923456524	0.729942305134535
GO:0005381	iron ion transmembrane transporter activity	2/2287	10/18639	0.2	1.62999562745955	0.352209923456524	0.729942305134535
GO:0008190	eukaryotic initiation factor 4E binding	2/2287	10/18639	0.2	1.62999562745955	0.352209923456524	0.729942305134535
GO:0008519	ammonium channel activity	2/2287	10/18639	0.2	1.62999562745955	0.352209923456524	0.729942305134535
GO:0008641	ubiquitin-like modifier activating enzyme activity	2/2287	10/18639	0.2	1.62999562745955	0.352209923456524	0.729942305134535
GO:0015658	branched-chain amino acid transmembrane transporter activity	2/2287	10/18639	0.2	1.62999562745955	0.352209923456524	0.729942305134535
GO:0031434	mitogen-activated protein kinase kinase binding	2/2287	10/18639	0.2	1.62999562745955	0.352209923456524	0.729942305134535
GO:0031957	very long-chain fatty acid-CoA ligase activity	2/2287	10/18639	0.2	1.62999562745955	0.352209923456524	0.729942305134535
GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity	2/2287	10/18639	0.2	1.62999562745955	0.352209923456524	0.729942305134535
GO:0036435	K48-linked polyubiquitin modification-dependent protein binding	2/2287	10/18639	0.2	1.62999562745955	0.352209923456524	0.729942305134535
GO:0043208	glycosphingolipid binding	2/2287	10/18639	0.2	1.62999562745955	0.352209923456524	0.729942305134535
GO:0043295	glutathione binding	2/2287	10/18639	0.2	1.62999562745955	0.352209923456524	0.729942305134535
GO:0043422	protein kinase B binding	2/2287	10/18639	0.2	1.62999562745955	0.352209923456524	0.729942305134535
GO:0045322	unmethylated CpG binding	2/2287	10/18639	0.2	1.62999562745955	0.352209923456524	0.729942305134535
GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding	2/2287	10/18639	0.2	1.62999562745955	0.352209923456524	0.729942305134535
GO:0140940	histone H2A methyltransferase activity	2/2287	10/18639	0.2	1.62999562745955	0.352209923456524	0.729942305134535
GO:1905394	retromer complex binding	2/2287	10/18639	0.2	1.62999562745955	0.352209923456524	0.729942305134535
GO:1990259	histone H2AQ104 methyltransferase activity	2/2287	10/18639	0.2	1.62999562745955	0.352209923456524	0.729942305134535
GO:1990763	arrestin family protein binding	2/2287	10/18639	0.2	1.62999562745955	0.352209923456524	0.729942305134535
GO:0140938	histone H3 methyltransferase activity	7/2287	47/18639	0.148936170212766	1.2138265310869	0.353475330075222	0.73138705756722
GO:0008234	cysteine-type peptidase activity	25/2287	187/18639	0.133689839572193	1.08956926969222	0.354775654903943	0.732899306358546
GO:0047498	calcium-dependent phospholipase A2 activity	5/2287	32/18639	0.15625	1.27343408395278	0.355493714850278	0.733205786878698
GO:0016853	isomerase activity	24/2287	180/18639	0.133333333333333	1.0866637516397	0.363972028283724	0.747040036749569
GO:0046943	carboxylic acid transmembrane transporter activity	25/2287	188/18639	0.132978723404255	1.08377368847045	0.365199679096241	0.747040036749569
GO:0004177	aminopeptidase activity	6/2287	40/18639	0.15	1.22249672059467	0.366509010769807	0.747040036749569
GO:0015144	carbohydrate transmembrane transporter activity	6/2287	40/18639	0.15	1.22249672059467	0.366509010769807	0.747040036749569
GO:0030331	nuclear estrogen receptor binding	6/2287	40/18639	0.15	1.22249672059467	0.366509010769807	0.747040036749569
GO:0050997	quaternary ammonium group binding	6/2287	40/18639	0.15	1.22249672059467	0.366509010769807	0.747040036749569
GO:0001848	complement binding	4/2287	25/18639	0.16	1.30399650196764	0.368586187518241	0.747040036749569
GO:0003707	nuclear steroid receptor activity	4/2287	25/18639	0.16	1.30399650196764	0.368586187518241	0.747040036749569
GO:0015271	outward rectifier potassium channel activity	4/2287	25/18639	0.16	1.30399650196764	0.368586187518241	0.747040036749569
GO:0017056	structural constituent of nuclear pore	4/2287	25/18639	0.16	1.30399650196764	0.368586187518241	0.747040036749569
GO:0120020	cholesterol transfer activity	4/2287	25/18639	0.16	1.30399650196764	0.368586187518241	0.747040036749569
GO:0005244	voltage-gated monoatomic ion channel activity	23/2287	173/18639	0.132947976878613	1.08352310495866	0.373568135385859	0.755946840002516
GO:0005342	organic acid transmembrane transporter activity	25/2287	189/18639	0.132275132275132	1.0780394361505	0.375684222599744	0.757845759382242
GO:0043177	organic acid binding	25/2287	189/18639	0.132275132275132	1.0780394361505	0.375684222599744	0.757845759382242
GO:0030296	protein tyrosine kinase activator activity	5/2287	33/18639	0.151515151515152	1.23484517231784	0.381112206569219	0.761828784653517
GO:0000900	mRNA regulatory element binding translation repressor activity	3/2287	18/18639	0.166666666666667	1.35832968954963	0.383031762404051	0.761828784653517
GO:0015172	acidic amino acid transmembrane transporter activity	3/2287	18/18639	0.166666666666667	1.35832968954963	0.383031762404051	0.761828784653517
GO:0015280	ligand-gated sodium channel activity	3/2287	18/18639	0.166666666666667	1.35832968954963	0.383031762404051	0.761828784653517
GO:0017075	syntaxin-1 binding	3/2287	18/18639	0.166666666666667	1.35832968954963	0.383031762404051	0.761828784653517
GO:0004722	protein serine/threonine phosphatase activity	14/2287	103/18639	0.135922330097087	1.10776401866183	0.384237235918409	0.761828784653517
GO:0005253	monoatomic anion channel activity	14/2287	103/18639	0.135922330097087	1.10776401866183	0.384237235918409	0.761828784653517
GO:0001530	lipopolysaccharide binding	6/2287	41/18639	0.146341463414634	1.19267972740943	0.389520119224739	0.761828784653517
GO:0016877	ligase activity, forming carbon-sulfur bonds	6/2287	41/18639	0.146341463414634	1.19267972740943	0.389520119224739	0.761828784653517
GO:0061650	ubiquitin-like protein conjugating enzyme activity	6/2287	41/18639	0.146341463414634	1.19267972740943	0.389520119224739	0.761828784653517
GO:0048306	calcium-dependent protein binding	11/2287	80/18639	0.1375	1.12062199387844	0.392125411750475	0.761828784653517
GO:0005227	calcium-activated cation channel activity	4/2287	26/18639	0.153846153846154	1.2538427903535	0.397872335511333	0.761828784653517
GO:0008143	poly(A) binding	4/2287	26/18639	0.153846153846154	1.2538427903535	0.397872335511333	0.761828784653517
GO:0015145	monosaccharide transmembrane transporter activity	4/2287	26/18639	0.153846153846154	1.2538427903535	0.397872335511333	0.761828784653517
GO:0019865	immunoglobulin binding	4/2287	26/18639	0.153846153846154	1.2538427903535	0.397872335511333	0.761828784653517
GO:0030247	polysaccharide binding	4/2287	26/18639	0.153846153846154	1.2538427903535	0.397872335511333	0.761828784653517
GO:0034237	protein kinase A regulatory subunit binding	4/2287	26/18639	0.153846153846154	1.2538427903535	0.397872335511333	0.761828784653517
GO:0050681	nuclear androgen receptor binding	4/2287	26/18639	0.153846153846154	1.2538427903535	0.397872335511333	0.761828784653517
GO:0004954	prostanoid receptor activity	2/2287	11/18639	0.181818181818182	1.48181420678141	0.398571379743075	0.761828784653517
GO:0005114	type II transforming growth factor beta receptor binding	2/2287	11/18639	0.181818181818182	1.48181420678141	0.398571379743075	0.761828784653517
GO:0005225	volume-sensitive anion channel activity	2/2287	11/18639	0.181818181818182	1.48181420678141	0.398571379743075	0.761828784653517
GO:0008172	S-methyltransferase activity	2/2287	11/18639	0.181818181818182	1.48181420678141	0.398571379743075	0.761828784653517
GO:0008432	JUN kinase binding	2/2287	11/18639	0.181818181818182	1.48181420678141	0.398571379743075	0.761828784653517
GO:0015217	ADP transmembrane transporter activity	2/2287	11/18639	0.181818181818182	1.48181420678141	0.398571379743075	0.761828784653517
GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	2/2287	11/18639	0.181818181818182	1.48181420678141	0.398571379743075	0.761828784653517
GO:0016725	oxidoreductase activity, acting on CH or CH2 groups	2/2287	11/18639	0.181818181818182	1.48181420678141	0.398571379743075	0.761828784653517
GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives	2/2287	11/18639	0.181818181818182	1.48181420678141	0.398571379743075	0.761828784653517
GO:0019107	myristoyltransferase activity	2/2287	11/18639	0.181818181818182	1.48181420678141	0.398571379743075	0.761828784653517
GO:0032794	GTPase activating protein binding	2/2287	11/18639	0.181818181818182	1.48181420678141	0.398571379743075	0.761828784653517
GO:0034713	type I transforming growth factor beta receptor binding	2/2287	11/18639	0.181818181818182	1.48181420678141	0.398571379743075	0.761828784653517
GO:0035252	UDP-xylosyltransferase activity	2/2287	11/18639	0.181818181818182	1.48181420678141	0.398571379743075	0.761828784653517
GO:0042285	xylosyltransferase activity	2/2287	11/18639	0.181818181818182	1.48181420678141	0.398571379743075	0.761828784653517
GO:0042608	T cell receptor binding	2/2287	11/18639	0.181818181818182	1.48181420678141	0.398571379743075	0.761828784653517
GO:0047676	arachidonate-CoA ligase activity	2/2287	11/18639	0.181818181818182	1.48181420678141	0.398571379743075	0.761828784653517
GO:1900750	oligopeptide binding	2/2287	11/18639	0.181818181818182	1.48181420678141	0.398571379743075	0.761828784653517
GO:0015932	nucleobase-containing compound transmembrane transporter activity	8/2287	57/18639	0.140350877192982	1.14385658067337	0.400068645714509	0.761828784653517
GO:0016504	peptidase activator activity	8/2287	57/18639	0.140350877192982	1.14385658067337	0.400068645714509	0.761828784653517
GO:0043022	ribosome binding	15/2287	112/18639	0.133928571428571	1.09151492910238	0.400152492949322	0.761828784653517
GO:0099094	ligand-gated monoatomic cation channel activity	18/2287	136/18639	0.132352941176471	1.07867357699529	0.403549408912395	0.767161136292839
GO:0090482	vitamin transmembrane transporter activity	5/2287	34/18639	0.147058823529412	1.19852619666144	0.406688821715723	0.771988958035598
GO:0016829	lyase activity	26/2287	200/18639	0.13	1.05949715784871	0.407699721583418	0.77276810261835
GO:0015605	organophosphate ester transmembrane transporter activity	7/2287	50/18639	0.14	1.14099693922169	0.416611167690992	0.779383376447944
GO:0048020	CCR chemokine receptor binding	7/2287	50/18639	0.14	1.14099693922169	0.416611167690992	0.779383376447944
GO:0003756	protein disulfide isomerase activity	3/2287	19/18639	0.157894736842105	1.28683865325754	0.417851227466264	0.779383376447944
GO:0015355	secondary active monocarboxylate transmembrane transporter activity	3/2287	19/18639	0.157894736842105	1.28683865325754	0.417851227466264	0.779383376447944
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	3/2287	19/18639	0.157894736842105	1.28683865325754	0.417851227466264	0.779383376447944
GO:0022821	solute:potassium antiporter activity	3/2287	19/18639	0.157894736842105	1.28683865325754	0.417851227466264	0.779383376447944
GO:0022840	leak channel activity	3/2287	19/18639	0.157894736842105	1.28683865325754	0.417851227466264	0.779383376447944
GO:0022842	narrow pore channel activity	3/2287	19/18639	0.157894736842105	1.28683865325754	0.417851227466264	0.779383376447944
GO:0042834	peptidoglycan binding	3/2287	19/18639	0.157894736842105	1.28683865325754	0.417851227466264	0.779383376447944
GO:0046527	glucosyltransferase activity	3/2287	19/18639	0.157894736842105	1.28683865325754	0.417851227466264	0.779383376447944
GO:0050145	nucleoside monophosphate kinase activity	3/2287	19/18639	0.157894736842105	1.28683865325754	0.417851227466264	0.779383376447944
GO:0004683	calcium/calmodulin-dependent protein kinase activity	4/2287	27/18639	0.148148148148148	1.20740416848856	0.426917749574217	0.782221152052401
GO:0005104	fibroblast growth factor receptor binding	4/2287	27/18639	0.148148148148148	1.20740416848856	0.426917749574217	0.782221152052401
GO:0016405	CoA-ligase activity	4/2287	27/18639	0.148148148148148	1.20740416848856	0.426917749574217	0.782221152052401
GO:0023026	MHC class II protein complex binding	4/2287	27/18639	0.148148148148148	1.20740416848856	0.426917749574217	0.782221152052401
GO:0034593	phosphatidylinositol bisphosphate phosphatase activity	4/2287	27/18639	0.148148148148148	1.20740416848856	0.426917749574217	0.782221152052401
GO:0035255	ionotropic glutamate receptor binding	4/2287	27/18639	0.148148148148148	1.20740416848856	0.426917749574217	0.782221152052401
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	16/2287	122/18639	0.131147540983607	1.06884959177676	0.428358017439363	0.782221152052401
GO:0004623	phospholipase A2 activity	5/2287	35/18639	0.142857142857143	1.16428259104254	0.432120266716596	0.782221152052401
GO:0005154	epidermal growth factor receptor binding	5/2287	35/18639	0.142857142857143	1.16428259104254	0.432120266716596	0.782221152052401
GO:0008200	ion channel inhibitor activity	6/2287	43/18639	0.13953488372093	1.13720625171597	0.435411704549748	0.782221152052401
GO:0003743	translation initiation factor activity	7/2287	51/18639	0.137254901960784	1.11862445021734	0.437608674314328	0.782221152052401
GO:0016830	carbon-carbon lyase activity	7/2287	51/18639	0.137254901960784	1.11862445021734	0.437608674314328	0.782221152052401
GO:0030544	Hsp70 protein binding	7/2287	51/18639	0.137254901960784	1.11862445021734	0.437608674314328	0.782221152052401
GO:0031406	carboxylic acid binding	24/2287	187/18639	0.128342245989305	1.04598649890453	0.439770835812598	0.782221152052401
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	9/2287	67/18639	0.134328358208955	1.09477318262209	0.440165178325054	0.782221152052401
GO:0042054	histone methyltransferase activity	9/2287	67/18639	0.134328358208955	1.09477318262209	0.440165178325054	0.782221152052401
GO:0000340	RNA 7-methylguanosine cap binding	2/2287	12/18639	0.166666666666667	1.35832968954963	0.443313370729773	0.782221152052401
GO:0003995	acyl-CoA dehydrogenase activity	2/2287	12/18639	0.166666666666667	1.35832968954963	0.443313370729773	0.782221152052401
GO:0004000	adenosine deaminase activity	2/2287	12/18639	0.166666666666667	1.35832968954963	0.443313370729773	0.782221152052401
GO:0004859	phospholipase inhibitor activity	2/2287	12/18639	0.166666666666667	1.35832968954963	0.443313370729773	0.782221152052401
GO:0005247	voltage-gated chloride channel activity	2/2287	12/18639	0.166666666666667	1.35832968954963	0.443313370729773	0.782221152052401
GO:0005436	sodium:phosphate symporter activity	2/2287	12/18639	0.166666666666667	1.35832968954963	0.443313370729773	0.782221152052401
GO:0008603	cAMP-dependent protein kinase regulator activity	2/2287	12/18639	0.166666666666667	1.35832968954963	0.443313370729773	0.782221152052401
GO:0015132	prostaglandin transmembrane transporter activity	2/2287	12/18639	0.166666666666667	1.35832968954963	0.443313370729773	0.782221152052401
GO:0015269	calcium-activated potassium channel activity	2/2287	12/18639	0.166666666666667	1.35832968954963	0.443313370729773	0.782221152052401
GO:0016273	arginine N-methyltransferase activity	2/2287	12/18639	0.166666666666667	1.35832968954963	0.443313370729773	0.782221152052401
GO:0016274	protein-arginine N-methyltransferase activity	2/2287	12/18639	0.166666666666667	1.35832968954963	0.443313370729773	0.782221152052401
GO:0016801	hydrolase activity, acting on ether bonds	2/2287	12/18639	0.166666666666667	1.35832968954963	0.443313370729773	0.782221152052401
GO:0016803	ether hydrolase activity	2/2287	12/18639	0.166666666666667	1.35832968954963	0.443313370729773	0.782221152052401
GO:0016840	carbon-nitrogen lyase activity	2/2287	12/18639	0.166666666666667	1.35832968954963	0.443313370729773	0.782221152052401
GO:0034452	dynactin binding	2/2287	12/18639	0.166666666666667	1.35832968954963	0.443313370729773	0.782221152052401
GO:0036009	protein-glutamine N-methyltransferase activity	2/2287	12/18639	0.166666666666667	1.35832968954963	0.443313370729773	0.782221152052401
GO:0042301	phosphate ion binding	2/2287	12/18639	0.166666666666667	1.35832968954963	0.443313370729773	0.782221152052401
GO:0045295	gamma-catenin binding	2/2287	12/18639	0.166666666666667	1.35832968954963	0.443313370729773	0.782221152052401
GO:0052890	oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor	2/2287	12/18639	0.166666666666667	1.35832968954963	0.443313370729773	0.782221152052401
GO:0070008	serine-type exopeptidase activity	2/2287	12/18639	0.166666666666667	1.35832968954963	0.443313370729773	0.782221152052401
GO:0106019	phosphatidylinositol-4,5-bisphosphate phosphatase activity	2/2287	12/18639	0.166666666666667	1.35832968954963	0.443313370729773	0.782221152052401
GO:1990459	transferrin receptor binding	2/2287	12/18639	0.166666666666667	1.35832968954963	0.443313370729773	0.782221152052401
GO:1990817	poly(A) RNA polymerase activity	2/2287	12/18639	0.166666666666667	1.35832968954963	0.443313370729773	0.782221152052401
GO:0004175	endopeptidase activity	51/2287	405/18639	0.125925925925926	1.02629354321527	0.443684103339746	0.782221152052401
GO:0000339	RNA cap binding	3/2287	20/18639	0.15	1.22249672059467	0.45199353126316	0.789302136683428
GO:0001972	retinoic acid binding	3/2287	20/18639	0.15	1.22249672059467	0.45199353126316	0.789302136683428
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	3/2287	20/18639	0.15	1.22249672059467	0.45199353126316	0.789302136683428
GO:0004745	all-trans-retinol dehydrogenase (NAD+) activity	3/2287	20/18639	0.15	1.22249672059467	0.45199353126316	0.789302136683428
GO:0015095	magnesium ion transmembrane transporter activity	3/2287	20/18639	0.15	1.22249672059467	0.45199353126316	0.789302136683428
GO:0016408	C-acyltransferase activity	3/2287	20/18639	0.15	1.22249672059467	0.45199353126316	0.789302136683428
GO:0043024	ribosomal small subunit binding	3/2287	20/18639	0.15	1.22249672059467	0.45199353126316	0.789302136683428
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	17/2287	132/18639	0.128787878787879	1.04961839647017	0.454716096556442	0.7923497235993
GO:0005242	inward rectifier potassium channel activity	4/2287	28/18639	0.142857142857143	1.16428259104254	0.455585699660825	0.7923497235993
GO:0046966	nuclear thyroid hormone receptor binding	4/2287	28/18639	0.142857142857143	1.16428259104254	0.455585699660825	0.7923497235993
GO:0004190	aspartic-type endopeptidase activity	5/2287	36/18639	0.138888888888889	1.13194140795802	0.45731121001989	0.79318545188761
GO:0003777	microtubule motor activity	9/2287	68/18639	0.132352941176471	1.07867357699529	0.458385054248691	0.79318545188761
GO:0001098	basal transcription machinery binding	8/2287	60/18639	0.133333333333333	1.0866637516397	0.458531450042255	0.79318545188761
GO:0001099	basal RNA polymerase II transcription machinery binding	8/2287	60/18639	0.133333333333333	1.0866637516397	0.458531450042255	0.79318545188761
GO:0008509	monoatomic anion transmembrane transporter activity	19/2287	149/18639	0.12751677852349	1.03925895710508	0.465869197986018	0.804796856118127
GO:0003724	RNA helicase activity	10/2287	77/18639	0.12987012987013	1.05843871912958	0.475249892481091	0.815569032420333
GO:0042393	histone binding	31/2287	247/18639	0.125506072874494	1.02287175002523	0.475420284754005	0.815569032420333
GO:0016836	hydro-lyase activity	8/2287	61/18639	0.131147540983607	1.06884959177676	0.477813445631271	0.815569032420333
GO:0046982	protein heterodimerization activity	46/2287	369/18639	0.124661246612466	1.01598643445988	0.477975555598535	0.815569032420333
GO:0004864	protein phosphatase inhibitor activity	7/2287	53/18639	0.132075471698113	1.07641220681291	0.479193250041361	0.815569032420333
GO:0051539	4 iron, 4 sulfur cluster binding	6/2287	45/18639	0.133333333333333	1.0866637516397	0.480646809111701	0.815569032420333
GO:0070001	aspartic-type peptidase activity	5/2287	37/18639	0.135135135135135	1.10134839693213	0.482174622311439	0.815569032420333
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	4/2287	29/18639	0.137931034482759	1.12413491548935	0.48375512224402	0.815569032420333
GO:0035250	UDP-galactosyltransferase activity	4/2287	29/18639	0.137931034482759	1.12413491548935	0.48375512224402	0.815569032420333
GO:0051861	glycolipid binding	4/2287	29/18639	0.137931034482759	1.12413491548935	0.48375512224402	0.815569032420333
GO:0097472	cyclin-dependent protein kinase activity	4/2287	29/18639	0.137931034482759	1.12413491548935	0.48375512224402	0.815569032420333
GO:0106222	lncRNA binding	4/2287	29/18639	0.137931034482759	1.12413491548935	0.48375512224402	0.815569032420333
GO:0001846	opsonin binding	3/2287	21/18639	0.142857142857143	1.16428259104254	0.485275813550805	0.815569032420333
GO:0061891	calcium ion sensor activity	3/2287	21/18639	0.142857142857143	1.16428259104254	0.485275813550805	0.815569032420333
GO:0008253	5'-nucleotidase activity	2/2287	13/18639	0.153846153846154	1.2538427903535	0.486135292966094	0.815569032420333
GO:0015651	quaternary ammonium group transmembrane transporter activity	2/2287	13/18639	0.153846153846154	1.2538427903535	0.486135292966094	0.815569032420333
GO:0017154	semaphorin receptor activity	2/2287	13/18639	0.153846153846154	1.2538427903535	0.486135292966094	0.815569032420333
GO:0031432	titin binding	2/2287	13/18639	0.153846153846154	1.2538427903535	0.486135292966094	0.815569032420333
GO:0043560	insulin receptor substrate binding	2/2287	13/18639	0.153846153846154	1.2538427903535	0.486135292966094	0.815569032420333
GO:0071714	icosanoid transmembrane transporter activity	2/2287	13/18639	0.153846153846154	1.2538427903535	0.486135292966094	0.815569032420333
GO:0071837	HMG box domain binding	2/2287	13/18639	0.153846153846154	1.2538427903535	0.486135292966094	0.815569032420333
GO:0097157	pre-mRNA intronic binding	2/2287	13/18639	0.153846153846154	1.2538427903535	0.486135292966094	0.815569032420333
GO:0008238	exopeptidase activity	13/2287	102/18639	0.127450980392157	1.03872270377325	0.486679888810268	0.815569032420333
GO:0022843	voltage-gated monoatomic cation channel activity	18/2287	143/18639	0.125874125874126	1.02587137392559	0.491960536584033	0.82334617761203
GO:0003925	G protein activity	7/2287	54/18639	0.12962962962963	1.05647864742749	0.499678592533645	0.835177076091949
GO:0015079	potassium ion transmembrane transporter activity	20/2287	160/18639	0.125	1.01874726716222	0.500718949833831	0.835830464897719
GO:0005501	retinoid binding	5/2287	38/18639	0.131578947368421	1.07236554438129	0.506631951562657	0.843512705900569
GO:0019840	isoprenoid binding	5/2287	38/18639	0.131578947368421	1.07236554438129	0.506631951562657	0.843512705900569
GO:0008186	ATP-dependent activity, acting on RNA	10/2287	79/18639	0.126582278481013	1.03164280218959	0.509163586275822	0.844761713133133
GO:0022839	monoatomic ion-gated channel activity	4/2287	30/18639	0.133333333333333	1.0866637516397	0.511320415330777	0.844761713133133
GO:0031210	phosphatidylcholine binding	4/2287	30/18639	0.133333333333333	1.0866637516397	0.511320415330777	0.844761713133133
GO:0031624	ubiquitin conjugating enzyme binding	4/2287	30/18639	0.133333333333333	1.0866637516397	0.511320415330777	0.844761713133133
GO:0048019	receptor antagonist activity	4/2287	30/18639	0.133333333333333	1.0866637516397	0.511320415330777	0.844761713133133
GO:0098918	structural constituent of synapse	4/2287	30/18639	0.133333333333333	1.0866637516397	0.511320415330777	0.844761713133133
GO:0016881	acid-amino acid ligase activity	3/2287	22/18639	0.136363636363636	1.11136065508606	0.51754873781938	0.852862004575598
GO:0140784	metal ion sensor activity	3/2287	22/18639	0.136363636363636	1.11136065508606	0.51754873781938	0.852862004575598
GO:0004896	cytokine receptor activity	12/2287	96/18639	0.125	1.01874726716222	0.519098567938118	0.854322067693552
GO:0016651	oxidoreductase activity, acting on NAD(P)H	11/2287	88/18639	0.125	1.01874726716222	0.522314247760121	0.856106267841468
GO:0001784	phosphotyrosine residue binding	6/2287	47/18639	0.127659574468085	1.04042274093163	0.524716402752993	0.856106267841468
GO:0005506	iron ion binding	19/2287	154/18639	0.123376623376623	1.0055167831731	0.526720360077006	0.856106267841468
GO:0004705	JUN kinase activity	2/2287	14/18639	0.142857142857143	1.16428259104254	0.52683462636398	0.856106267841468
GO:0015386	potassium:proton antiporter activity	2/2287	14/18639	0.142857142857143	1.16428259104254	0.52683462636398	0.856106267841468
GO:0016530	metallochaperone activity	2/2287	14/18639	0.142857142857143	1.16428259104254	0.52683462636398	0.856106267841468
GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity	2/2287	14/18639	0.142857142857143	1.16428259104254	0.52683462636398	0.856106267841468
GO:0070742	C2H2 zinc finger domain binding	2/2287	14/18639	0.142857142857143	1.16428259104254	0.52683462636398	0.856106267841468
GO:0098847	sequence-specific single stranded DNA binding	2/2287	14/18639	0.142857142857143	1.16428259104254	0.52683462636398	0.856106267841468
GO:1901612	cardiolipin binding	2/2287	14/18639	0.142857142857143	1.16428259104254	0.52683462636398	0.856106267841468
GO:0005164	tumor necrosis factor receptor binding	4/2287	31/18639	0.129032258064516	1.05161008223197	0.538190984227214	0.872357426574842
GO:0016878	acid-thiol ligase activity	4/2287	31/18639	0.129032258064516	1.05161008223197	0.538190984227214	0.872357426574842
GO:0019212	phosphatase inhibitor activity	7/2287	56/18639	0.125	1.01874726716222	0.53980752549851	0.872779252910279
GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	7/2287	56/18639	0.125	1.01874726716222	0.53980752549851	0.872779252910279
GO:0004497	monooxygenase activity	13/2287	106/18639	0.122641509433962	0.999525620611991	0.545177776906581	0.879413128285738
GO:0003887	DNA-directed DNA polymerase activity	3/2287	23/18639	0.130434782608696	1.06304062660406	0.54869366123811	0.879413128285738
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	3/2287	23/18639	0.130434782608696	1.06304062660406	0.54869366123811	0.879413128285738
GO:0005283	amino acid:sodium symporter activity	3/2287	23/18639	0.130434782608696	1.06304062660406	0.54869366123811	0.879413128285738
GO:0042171	lysophosphatidic acid acyltransferase activity	3/2287	23/18639	0.130434782608696	1.06304062660406	0.54869366123811	0.879413128285738
GO:0071617	lysophospholipid acyltransferase activity	3/2287	23/18639	0.130434782608696	1.06304062660406	0.54869366123811	0.879413128285738
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	3/2287	23/18639	0.130434782608696	1.06304062660406	0.54869366123811	0.879413128285738
GO:0019843	rRNA binding	8/2287	65/18639	0.123076923076923	1.0030742322828	0.552848780914301	0.880780741877663
GO:0061791	GTPase motor activity	5/2287	40/18639	0.125	1.01874726716222	0.554056603299729	0.880780741877663
GO:1990606	membrane scission GTPase motor activity	5/2287	40/18639	0.125	1.01874726716222	0.554056603299729	0.880780741877663
GO:0015103	inorganic anion transmembrane transporter activity	20/2287	165/18639	0.121212121212121	0.987876137854275	0.559112050820401	0.880780741877663
GO:0070279	vitamin B6 binding	7/2287	57/18639	0.12280701754386	1.0008745080892	0.55937096866827	0.880780741877663
GO:0008378	galactosyltransferase activity	4/2287	32/18639	0.125	1.01874726716222	0.564290594138205	0.880780741877663
GO:0030515	snoRNA binding	4/2287	32/18639	0.125	1.01874726716222	0.564290594138205	0.880780741877663
GO:0031369	translation initiation factor binding	4/2287	32/18639	0.125	1.01874726716222	0.564290594138205	0.880780741877663
GO:0043425	bHLH transcription factor binding	4/2287	32/18639	0.125	1.01874726716222	0.564290594138205	0.880780741877663
GO:0070717	poly-purine tract binding	4/2287	32/18639	0.125	1.01874726716222	0.564290594138205	0.880780741877663
GO:0005267	potassium channel activity	15/2287	124/18639	0.120967741935484	0.985884452092472	0.564690209909212	0.880780741877663
GO:0004089	carbonate dehydratase activity	2/2287	15/18639	0.133333333333333	1.0866637516397	0.565287406985975	0.880780741877663
GO:0004129	cytochrome-c oxidase activity	2/2287	15/18639	0.133333333333333	1.0866637516397	0.565287406985975	0.880780741877663
GO:0004953	icosanoid receptor activity	2/2287	15/18639	0.133333333333333	1.0866637516397	0.565287406985975	0.880780741877663
GO:0005041	low-density lipoprotein particle receptor activity	2/2287	15/18639	0.133333333333333	1.0866637516397	0.565287406985975	0.880780741877663
GO:0008020	G protein-coupled photoreceptor activity	2/2287	15/18639	0.133333333333333	1.0866637516397	0.565287406985975	0.880780741877663
GO:0008252	nucleotidase activity	2/2287	15/18639	0.133333333333333	1.0866637516397	0.565287406985975	0.880780741877663
GO:0010181	FMN binding	2/2287	15/18639	0.133333333333333	1.0866637516397	0.565287406985975	0.880780741877663
GO:0015556	C4-dicarboxylate transmembrane transporter activity	2/2287	15/18639	0.133333333333333	1.0866637516397	0.565287406985975	0.880780741877663
GO:0034483	heparan sulfate sulfotransferase activity	2/2287	15/18639	0.133333333333333	1.0866637516397	0.565287406985975	0.880780741877663
GO:0050700	CARD domain binding	2/2287	15/18639	0.133333333333333	1.0866637516397	0.565287406985975	0.880780741877663
GO:0141050	histone H3K deacetylase activity	2/2287	15/18639	0.133333333333333	1.0866637516397	0.565287406985975	0.880780741877663
GO:0141051	histone H4K deacetylase activity	2/2287	15/18639	0.133333333333333	1.0866637516397	0.565287406985975	0.880780741877663
GO:0005254	chloride channel activity	10/2287	83/18639	0.120481927710843	0.981925076782864	0.574798581038734	0.894517259730171
GO:0001727	lipid kinase activity	5/2287	41/18639	0.121951219512195	0.993899772841191	0.576908892754589	0.895635398039995
GO:0008227	G protein-coupled amine receptor activity	5/2287	41/18639	0.121951219512195	0.993899772841191	0.576908892754589	0.895635398039995
GO:0050699	WW domain binding	3/2287	24/18639	0.125	1.01874726716222	0.578619670746875	0.897209055724371
GO:0020037	heme binding	17/2287	142/18639	0.119718309859155	0.975701607986353	0.581784122030939	0.90103028285658
GO:0004252	serine-type endopeptidase activity	21/2287	176/18639	0.119318181818182	0.972440573200302	0.589266662231673	0.910875530249012
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	4/2287	33/18639	0.121212121212121	0.987876137854275	0.589556578630479	0.910875530249012
GO:0022836	gated channel activity	38/2287	318/18639	0.119496855345912	0.973896758545017	0.595624521239394	0.919147192847842
GO:0004707	MAP kinase activity	2/2287	16/18639	0.125	1.01874726716222	0.601432012022263	0.91929097324543
GO:0005521	lamin binding	2/2287	16/18639	0.125	1.01874726716222	0.601432012022263	0.91929097324543
GO:0008296	3'-5'-DNA exonuclease activity	2/2287	16/18639	0.125	1.01874726716222	0.601432012022263	0.91929097324543
GO:0015378	sodium:chloride symporter activity	2/2287	16/18639	0.125	1.01874726716222	0.601432012022263	0.91929097324543
GO:0016675	oxidoreductase activity, acting on a heme group of donors	2/2287	16/18639	0.125	1.01874726716222	0.601432012022263	0.91929097324543
GO:0022841	potassium ion leak channel activity	2/2287	16/18639	0.125	1.01874726716222	0.601432012022263	0.91929097324543
GO:0031435	mitogen-activated protein kinase kinase kinase binding	2/2287	16/18639	0.125	1.01874726716222	0.601432012022263	0.91929097324543
GO:0097027	ubiquitin-protein transferase activator activity	2/2287	16/18639	0.125	1.01874726716222	0.601432012022263	0.91929097324543
GO:0030145	manganese ion binding	8/2287	68/18639	0.117647058823529	0.95882095732915	0.606010019970636	0.921283521088649
GO:0005537	D-mannose binding	3/2287	25/18639	0.12	0.977997376475732	0.607260600278052	0.921283521088649
GO:0015296	monoatomic anion:monoatomic cation symporter activity	3/2287	25/18639	0.12	0.977997376475732	0.607260600278052	0.921283521088649
GO:0015645	fatty acid ligase activity	3/2287	25/18639	0.12	0.977997376475732	0.607260600278052	0.921283521088649
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	3/2287	25/18639	0.12	0.977997376475732	0.607260600278052	0.921283521088649
GO:0120515	fatty acid-CoA ligase activity	3/2287	25/18639	0.12	0.977997376475732	0.607260600278052	0.921283521088649
GO:0016597	amino acid binding	6/2287	51/18639	0.117647058823529	0.95882095732915	0.607746471953585	0.921283521088649
GO:0015035	protein-disulfide reductase activity	4/2287	34/18639	0.117647058823529	0.95882095732915	0.613938946219113	0.926306475713949
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	4/2287	34/18639	0.117647058823529	0.95882095732915	0.613938946219113	0.926306475713949
GO:0030332	cyclin binding	4/2287	34/18639	0.117647058823529	0.95882095732915	0.613938946219113	0.926306475713949
GO:0052866	phosphatidylinositol phosphate phosphatase activity	4/2287	34/18639	0.117647058823529	0.95882095732915	0.613938946219113	0.926306475713949
GO:0004712	protein serine/threonine/tyrosine kinase activity	5/2287	43/18639	0.116279069767442	0.947671876429973	0.620665721746798	0.933675454635996
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	6/2287	52/18639	0.115384615384615	0.940382092765127	0.627215112774474	0.933675454635996
GO:0022834	ligand-gated channel activity	22/2287	188/18639	0.117021276595745	0.953720845853994	0.627622529377763	0.933675454635996
GO:0005085	guanyl-nucleotide exchange factor activity	27/2287	230/18639	0.117391304347826	0.956736563943651	0.62771912981527	0.933675454635996
GO:0015293	symporter activity	17/2287	146/18639	0.116438356164384	0.948970057082617	0.629338779458899	0.933675454635996
GO:0004529	DNA exonuclease activity	3/2287	26/18639	0.115384615384615	0.940382092765127	0.634572113073711	0.933675454635996
GO:0052742	phosphatidylinositol kinase activity	3/2287	26/18639	0.115384615384615	0.940382092765127	0.634572113073711	0.933675454635996
GO:0004438	phosphatidylinositol-3-phosphate phosphatase activity	2/2287	17/18639	0.117647058823529	0.95882095732915	0.635255738644633	0.933675454635996
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	2/2287	17/18639	0.117647058823529	0.95882095732915	0.635255738644633	0.933675454635996
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	2/2287	17/18639	0.117647058823529	0.95882095732915	0.635255738644633	0.933675454635996
GO:0005092	GDP-dissociation inhibitor activity	2/2287	17/18639	0.117647058823529	0.95882095732915	0.635255738644633	0.933675454635996
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	2/2287	17/18639	0.117647058823529	0.95882095732915	0.635255738644633	0.933675454635996
GO:0015278	intracellularly gated calcium channel activity	2/2287	17/18639	0.117647058823529	0.95882095732915	0.635255738644633	0.933675454635996
GO:0016018	cyclosporin A binding	2/2287	17/18639	0.117647058823529	0.95882095732915	0.635255738644633	0.933675454635996
GO:0019198	transmembrane receptor protein phosphatase activity	2/2287	17/18639	0.117647058823529	0.95882095732915	0.635255738644633	0.933675454635996
GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	2/2287	17/18639	0.117647058823529	0.95882095732915	0.635255738644633	0.933675454635996
GO:0031489	myosin V binding	2/2287	17/18639	0.117647058823529	0.95882095732915	0.635255738644633	0.933675454635996
GO:0045125	bioactive lipid receptor activity	2/2287	17/18639	0.117647058823529	0.95882095732915	0.635255738644633	0.933675454635996
GO:0045236	CXCR chemokine receptor binding	2/2287	17/18639	0.117647058823529	0.95882095732915	0.635255738644633	0.933675454635996
GO:0070402	NADPH binding	2/2287	17/18639	0.117647058823529	0.95882095732915	0.635255738644633	0.933675454635996
GO:0070492	oligosaccharide binding	2/2287	17/18639	0.117647058823529	0.95882095732915	0.635255738644633	0.933675454635996
GO:1990226	histone methyltransferase binding	2/2287	17/18639	0.117647058823529	0.95882095732915	0.635255738644633	0.933675454635996
GO:0004386	helicase activity	18/2287	155/18639	0.116129032258065	0.946449074008773	0.635508701057601	0.933675454635996
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	15/2287	130/18639	0.115384615384615	0.940382092765127	0.640648657275003	0.940153730801515
GO:0043014	alpha-tubulin binding	5/2287	44/18639	0.113636363636364	0.926133879238383	0.641501702717014	0.940333361499768
GO:0016835	carbon-oxygen lyase activity	9/2287	79/18639	0.113924050632911	0.928478521970632	0.645387624855431	0.943865524685204
GO:0005544	calcium-dependent phospholipid binding	6/2287	53/18639	0.113207547169811	0.922639034411068	0.646111520782957	0.943865524685204
GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	6/2287	53/18639	0.113207547169811	0.922639034411068	0.646111520782957	0.943865524685204
GO:0140104	molecular carrier activity	29/2287	249/18639	0.116465863453815	0.949194240890102	0.647539638739655	0.94487926877317
GO:0004197	cysteine-type endopeptidase activity	10/2287	88/18639	0.113636363636364	0.926133879238383	0.650968220312043	0.948806454746999
GO:0005484	SNAP receptor activity	4/2287	36/18639	0.111111111111111	0.905553126366419	0.659910447365349	0.958827561802621
GO:0055106	ubiquitin-protein transferase regulator activity	4/2287	36/18639	0.111111111111111	0.905553126366419	0.659910447365349	0.958827561802621
GO:0008395	steroid hydroxylase activity	3/2287	27/18639	0.111111111111111	0.905553126366419	0.660528908511147	0.958827561802621
GO:0042605	peptide antigen binding	5/2287	45/18639	0.111111111111111	0.905553126366419	0.661608564417677	0.958827561802621
GO:0140463	chromatin-protein adaptor activity	6/2287	54/18639	0.111111111111111	0.905553126366419	0.66441563681412	0.958827561802621
GO:0008409	5'-3' exonuclease activity	2/2287	18/18639	0.111111111111111	0.905553126366419	0.666783735674705	0.958827561802621
GO:0015373	monoatomic anion:sodium symporter activity	2/2287	18/18639	0.111111111111111	0.905553126366419	0.666783735674705	0.958827561802621
GO:0016854	racemase and epimerase activity	2/2287	18/18639	0.111111111111111	0.905553126366419	0.666783735674705	0.958827561802621
GO:0030228	lipoprotein particle receptor activity	2/2287	18/18639	0.111111111111111	0.905553126366419	0.666783735674705	0.958827561802621
GO:0050811	GABA receptor binding	2/2287	18/18639	0.111111111111111	0.905553126366419	0.666783735674705	0.958827561802621
GO:0052744	phosphatidylinositol monophosphate phosphatase activity	2/2287	18/18639	0.111111111111111	0.905553126366419	0.666783735674705	0.958827561802621
GO:1990381	ubiquitin-specific protease binding	2/2287	18/18639	0.111111111111111	0.905553126366419	0.666783735674705	0.958827561802621
GO:0042379	chemokine receptor binding	8/2287	72/18639	0.111111111111111	0.905553126366419	0.671471886259211	0.964491425910273
GO:0009055	electron transfer activity	13/2287	116/18639	0.112068965517241	0.913359618835095	0.678806534539985	0.972247813851042
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	5/2287	46/18639	0.108695652173913	0.885867188836714	0.680968652726724	0.972247813851042
GO:0023023	MHC protein complex binding	4/2287	37/18639	0.108108108108108	0.881078717545705	0.68145418373552	0.972247813851042
GO:0016866	intramolecular transferase activity	3/2287	28/18639	0.107142857142857	0.873211943281904	0.685122093573186	0.972247813851042
GO:0046875	ephrin receptor binding	3/2287	28/18639	0.107142857142857	0.873211943281904	0.685122093573186	0.972247813851042
GO:0141052	histone H3 demethylase activity	3/2287	28/18639	0.107142857142857	0.873211943281904	0.685122093573186	0.972247813851042
GO:0004521	RNA endonuclease activity	8/2287	73/18639	0.10958904109589	0.893148289018934	0.686757933824041	0.972247813851042
GO:0015276	ligand-gated monoatomic ion channel activity	21/2287	186/18639	0.112903225806452	0.920158821952974	0.691787395396064	0.972247813851042
GO:0022804	active transmembrane transporter activity	53/2287	457/18639	0.115973741794311	0.945183460124249	0.692536744512334	0.972247813851042
GO:0001664	G protein-coupled receptor binding	34/2287	297/18639	0.114478114478114	0.932994130195704	0.694435241391214	0.972247813851042
GO:0046906	tetrapyrrole binding	17/2287	152/18639	0.111842105263158	0.911510712724093	0.695396373792671	0.972247813851042
GO:0008301	DNA binding, bending	2/2287	19/18639	0.105263157894737	0.857892435505028	0.696069913110993	0.972247813851042
GO:0008574	plus-end-directed microtubule motor activity	2/2287	19/18639	0.105263157894737	0.857892435505028	0.696069913110993	0.972247813851042
GO:0016918	retinal binding	2/2287	19/18639	0.105263157894737	0.857892435505028	0.696069913110993	0.972247813851042
GO:0030506	ankyrin binding	2/2287	19/18639	0.105263157894737	0.857892435505028	0.696069913110993	0.972247813851042
GO:0070003	threonine-type peptidase activity	2/2287	19/18639	0.105263157894737	0.857892435505028	0.696069913110993	0.972247813851042
GO:0140036	ubiquitin-modified protein reader activity	2/2287	19/18639	0.105263157894737	0.857892435505028	0.696069913110993	0.972247813851042
GO:0030170	pyridoxal phosphate binding	6/2287	56/18639	0.107142857142857	0.873211943281904	0.699188263956927	0.972247813851042
GO:0004620	phospholipase activity	12/2287	109/18639	0.110091743119266	0.897245299519021	0.699309571043524	0.972247813851042
GO:0140359	ABC-type transporter activity	5/2287	47/18639	0.106382978723404	0.867018950776359	0.699570111056931	0.972247813851042
GO:0038024	cargo receptor activity	7/2287	65/18639	0.107692307692308	0.877689953247452	0.700014943727317	0.972247813851042
GO:0042162	telomeric DNA binding	4/2287	38/18639	0.105263157894737	0.857892435505028	0.702021505167622	0.972247813851042
GO:0003785	actin monomer binding	3/2287	29/18639	0.103448275862069	0.843101186617011	0.708356744111167	0.972247813851042
GO:0005416	amino acid:monoatomic cation symporter activity	3/2287	29/18639	0.103448275862069	0.843101186617011	0.708356744111167	0.972247813851042
GO:0016417	S-acyltransferase activity	3/2287	29/18639	0.103448275862069	0.843101186617011	0.708356744111167	0.972247813851042
GO:0008235	metalloexopeptidase activity	7/2287	66/18639	0.106060606060606	0.864391620622491	0.715332033771289	0.972247813851042
GO:0000217	DNA secondary structure binding	4/2287	39/18639	0.102564102564103	0.835895193569002	0.721611030988665	0.972247813851042
GO:0005326	neurotransmitter transmembrane transporter activity	2/2287	20/18639	0.1	0.814997813729777	0.723189511094086	0.972247813851042
GO:0010851	cyclase regulator activity	2/2287	20/18639	0.1	0.814997813729777	0.723189511094086	0.972247813851042
GO:0016505	peptidase activator activity involved in apoptotic process	2/2287	20/18639	0.1	0.814997813729777	0.723189511094086	0.972247813851042
GO:0140713	histone chaperone activity	18/2287	164/18639	0.109756097560976	0.894509795557072	0.728612609288269	0.972247813851042
GO:0000182	rDNA binding	1/2287	10/18639	0.1	0.814997813729777	0.730017259048019	0.972247813851042
GO:0004090	carbonyl reductase (NADPH) activity	1/2287	10/18639	0.1	0.814997813729777	0.730017259048019	0.972247813851042
GO:0004862	cAMP-dependent protein kinase inhibitor activity	1/2287	10/18639	0.1	0.814997813729777	0.730017259048019	0.972247813851042
GO:0004983	neuropeptide Y receptor activity	1/2287	10/18639	0.1	0.814997813729777	0.730017259048019	0.972247813851042
GO:0005345	purine nucleobase transmembrane transporter activity	1/2287	10/18639	0.1	0.814997813729777	0.730017259048019	0.972247813851042
GO:0008239	dipeptidyl-peptidase activity	1/2287	10/18639	0.1	0.814997813729777	0.730017259048019	0.972247813851042
GO:0015203	polyamine transmembrane transporter activity	1/2287	10/18639	0.1	0.814997813729777	0.730017259048019	0.972247813851042
GO:0015279	store-operated calcium channel activity	1/2287	10/18639	0.1	0.814997813729777	0.730017259048019	0.972247813851042
GO:0016175	superoxide-generating NAD(P)H oxidase activity	1/2287	10/18639	0.1	0.814997813729777	0.730017259048019	0.972247813851042
GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor	1/2287	10/18639	0.1	0.814997813729777	0.730017259048019	0.972247813851042
GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines	1/2287	10/18639	0.1	0.814997813729777	0.730017259048019	0.972247813851042
GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor	1/2287	10/18639	0.1	0.814997813729777	0.730017259048019	0.972247813851042
GO:0019911	structural constituent of myelin sheath	1/2287	10/18639	0.1	0.814997813729777	0.730017259048019	0.972247813851042
GO:0030957	Tat protein binding	1/2287	10/18639	0.1	0.814997813729777	0.730017259048019	0.972247813851042
GO:0031078	histone H3K14 deacetylase activity, hydrolytic mechanism	1/2287	10/18639	0.1	0.814997813729777	0.730017259048019	0.972247813851042
GO:0032052	bile acid binding	1/2287	10/18639	0.1	0.814997813729777	0.730017259048019	0.972247813851042
GO:0032395	MHC class II receptor activity	1/2287	10/18639	0.1	0.814997813729777	0.730017259048019	0.972247813851042
GO:0034739	histone H4K16 deacetylase activity, hydrolytic mechanism	1/2287	10/18639	0.1	0.814997813729777	0.730017259048019	0.972247813851042
GO:0035256	G protein-coupled glutamate receptor binding	1/2287	10/18639	0.1	0.814997813729777	0.730017259048019	0.972247813851042
GO:0042166	acetylcholine binding	1/2287	10/18639	0.1	0.814997813729777	0.730017259048019	0.972247813851042
GO:0043225	ATPase-coupled inorganic anion transmembrane transporter activity	1/2287	10/18639	0.1	0.814997813729777	0.730017259048019	0.972247813851042
GO:0047429	nucleoside triphosphate diphosphatase activity	1/2287	10/18639	0.1	0.814997813729777	0.730017259048019	0.972247813851042
GO:0050308	sugar-phosphatase activity	1/2287	10/18639	0.1	0.814997813729777	0.730017259048019	0.972247813851042
GO:0051378	serotonin binding	1/2287	10/18639	0.1	0.814997813729777	0.730017259048019	0.972247813851042
GO:0070097	delta-catenin binding	1/2287	10/18639	0.1	0.814997813729777	0.730017259048019	0.972247813851042
GO:0070739	protein-glutamic acid ligase activity	1/2287	10/18639	0.1	0.814997813729777	0.730017259048019	0.972247813851042
GO:0070740	tubulin-glutamic acid ligase activity	1/2287	10/18639	0.1	0.814997813729777	0.730017259048019	0.972247813851042
GO:0071723	lipopeptide binding	1/2287	10/18639	0.1	0.814997813729777	0.730017259048019	0.972247813851042
GO:0098505	G-rich strand telomeric DNA binding	1/2287	10/18639	0.1	0.814997813729777	0.730017259048019	0.972247813851042
GO:0140135	mechanosensitive monoatomic cation channel activity	1/2287	10/18639	0.1	0.814997813729777	0.730017259048019	0.972247813851042
GO:0140999	histone H3K4 trimethyltransferase activity	1/2287	10/18639	0.1	0.814997813729777	0.730017259048019	0.972247813851042
GO:0141109	transporter activator activity	1/2287	10/18639	0.1	0.814997813729777	0.730017259048019	0.972247813851042
GO:0180032	histone H4K5 deacetylase activity, hydrolytic mechanism	1/2287	10/18639	0.1	0.814997813729777	0.730017259048019	0.972247813851042
GO:0180033	histone H4K8 deacetylase activity, hydrolytic mechanism	1/2287	10/18639	0.1	0.814997813729777	0.730017259048019	0.972247813851042
GO:1990162	histone H3K4 deacetylase activity, hydrolytic mechanism	1/2287	10/18639	0.1	0.814997813729777	0.730017259048019	0.972247813851042
GO:1990757	ubiquitin ligase activator activity	1/2287	10/18639	0.1	0.814997813729777	0.730017259048019	0.972247813851042
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	3/2287	30/18639	0.1	0.814997813729777	0.73024966953121	0.972247813851042
GO:0032452	histone demethylase activity	3/2287	30/18639	0.1	0.814997813729777	0.73024966953121	0.972247813851042
GO:0016410	N-acyltransferase activity	10/2287	94/18639	0.106382978723404	0.867018950776359	0.731376458511573	0.972247813851042
GO:0015108	chloride transmembrane transporter activity	13/2287	121/18639	0.107438016528926	0.87561748582538	0.736285513707309	0.972247813851042
GO:0015036	disulfide oxidoreductase activity	4/2287	40/18639	0.1	0.814997813729777	0.740228189620769	0.972247813851042
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	4/2287	40/18639	0.1	0.814997813729777	0.740228189620769	0.972247813851042
GO:0015459	potassium channel regulator activity	6/2287	59/18639	0.101694915254237	0.828811335996383	0.746639453607555	0.972247813851042
GO:0045309	protein phosphorylated amino acid binding	6/2287	59/18639	0.101694915254237	0.828811335996383	0.746639453607555	0.972247813851042
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	2/2287	21/18639	0.0952380952380952	0.776188394028359	0.748233058203904	0.972247813851042
GO:0008373	sialyltransferase activity	2/2287	21/18639	0.0952380952380952	0.776188394028359	0.748233058203904	0.972247813851042
GO:0072542	protein phosphatase activator activity	2/2287	21/18639	0.0952380952380952	0.776188394028359	0.748233058203904	0.972247813851042
GO:0005184	neuropeptide hormone activity	3/2287	31/18639	0.0967741935483871	0.788707561673978	0.750827385813781	0.972247813851042
GO:0005452	solute:inorganic anion antiporter activity	3/2287	31/18639	0.0967741935483871	0.788707561673978	0.750827385813781	0.972247813851042
GO:0016411	acylglycerol O-acyltransferase activity	3/2287	31/18639	0.0967741935483871	0.788707561673978	0.750827385813781	0.972247813851042
GO:0140457	protein demethylase activity	3/2287	31/18639	0.0967741935483871	0.788707561673978	0.750827385813781	0.972247813851042
GO:0008081	phosphoric diester hydrolase activity	9/2287	87/18639	0.103448275862069	0.843101186617011	0.755411649022934	0.972247813851042
GO:0098960	postsynaptic neurotransmitter receptor activity	7/2287	69/18639	0.101449275362319	0.8268093762476	0.758055583185881	0.972247813851042
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	6/2287	60/18639	0.1	0.814997813729777	0.761193354781071	0.972247813851042
GO:0000014	single-stranded DNA endodeoxyribonuclease activity	1/2287	11/18639	0.0909090909090909	0.740907103390706	0.763161846978513	0.972247813851042
GO:0000099	sulfur amino acid transmembrane transporter activity	1/2287	11/18639	0.0909090909090909	0.740907103390706	0.763161846978513	0.972247813851042
GO:0001851	complement component C3b binding	1/2287	11/18639	0.0909090909090909	0.740907103390706	0.763161846978513	0.972247813851042
GO:0004143	ATP-dependent diacylglycerol kinase activity	1/2287	11/18639	0.0909090909090909	0.740907103390706	0.763161846978513	0.972247813851042
GO:0004523	RNA-DNA hybrid ribonuclease activity	1/2287	11/18639	0.0909090909090909	0.740907103390706	0.763161846978513	0.972247813851042
GO:0005221	intracellularly cyclic nucleotide-activated monoatomic cation channel activity	1/2287	11/18639	0.0909090909090909	0.740907103390706	0.763161846978513	0.972247813851042
GO:0008046	axon guidance receptor activity	1/2287	11/18639	0.0909090909090909	0.740907103390706	0.763161846978513	0.972247813851042
GO:0008199	ferric iron binding	1/2287	11/18639	0.0909090909090909	0.740907103390706	0.763161846978513	0.972247813851042
GO:0010854	adenylate cyclase regulator activity	1/2287	11/18639	0.0909090909090909	0.740907103390706	0.763161846978513	0.972247813851042
GO:0015205	nucleobase transmembrane transporter activity	1/2287	11/18639	0.0909090909090909	0.740907103390706	0.763161846978513	0.972247813851042
GO:0019203	carbohydrate phosphatase activity	1/2287	11/18639	0.0909090909090909	0.740907103390706	0.763161846978513	0.972247813851042
GO:0019206	nucleoside kinase activity	1/2287	11/18639	0.0909090909090909	0.740907103390706	0.763161846978513	0.972247813851042
GO:0019215	intermediate filament binding	1/2287	11/18639	0.0909090909090909	0.740907103390706	0.763161846978513	0.972247813851042
GO:0032129	histone H3K9 deacetylase activity, hydrolytic mechanism	1/2287	11/18639	0.0909090909090909	0.740907103390706	0.763161846978513	0.972247813851042
GO:0032404	mismatch repair complex binding	1/2287	11/18639	0.0909090909090909	0.740907103390706	0.763161846978513	0.972247813851042
GO:0034594	phosphatidylinositol trisphosphate phosphatase activity	1/2287	11/18639	0.0909090909090909	0.740907103390706	0.763161846978513	0.972247813851042
GO:0043855	cyclic nucleotide-activated monoatomic ion channel activity	1/2287	11/18639	0.0909090909090909	0.740907103390706	0.763161846978513	0.972247813851042
GO:0045294	alpha-catenin binding	1/2287	11/18639	0.0909090909090909	0.740907103390706	0.763161846978513	0.972247813851042
GO:0050786	RAGE receptor binding	1/2287	11/18639	0.0909090909090909	0.740907103390706	0.763161846978513	0.972247813851042
GO:0098973	structural constituent of postsynaptic actin cytoskeleton	1/2287	11/18639	0.0909090909090909	0.740907103390706	0.763161846978513	0.972247813851042
GO:0099508	voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	1/2287	11/18639	0.0909090909090909	0.740907103390706	0.763161846978513	0.972247813851042
GO:0099528	G protein-coupled neurotransmitter receptor activity	1/2287	11/18639	0.0909090909090909	0.740907103390706	0.763161846978513	0.972247813851042
GO:0140937	histone H4K12 deacetylase activity, hydrolytic mechanism	1/2287	11/18639	0.0909090909090909	0.740907103390706	0.763161846978513	0.972247813851042
GO:0180030	inositol phosphate kinase activity	1/2287	11/18639	0.0909090909090909	0.740907103390706	0.763161846978513	0.972247813851042
GO:0033293	monocarboxylic acid binding	8/2287	79/18639	0.10126582278481	0.825314241751673	0.768755287750441	0.972247813851042
GO:0015106	bicarbonate transmembrane transporter activity	3/2287	32/18639	0.09375	0.764060450371666	0.770124295297461	0.972247813851042
GO:0022884	macromolecule transmembrane transporter activity	3/2287	32/18639	0.09375	0.764060450371666	0.770124295297461	0.972247813851042
GO:0042910	xenobiotic transmembrane transporter activity	3/2287	32/18639	0.09375	0.764060450371666	0.770124295297461	0.972247813851042
GO:0160041	neuropeptide activity	3/2287	32/18639	0.09375	0.764060450371666	0.770124295297461	0.972247813851042
GO:0000510	H3-H4 histone complex chaperone activity	16/2287	151/18639	0.105960264900662	0.863573842362678	0.770537460082199	0.972247813851042
GO:0140584	chromatin extrusion motor activity	16/2287	151/18639	0.105960264900662	0.863573842362678	0.770537460082199	0.972247813851042
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	16/2287	151/18639	0.105960264900662	0.863573842362678	0.770537460082199	0.972247813851042
GO:0140849	ATP-dependent H2AZ histone chaperone activity	16/2287	151/18639	0.105960264900662	0.863573842362678	0.770537460082199	0.972247813851042
GO:0005243	gap junction channel activity	2/2287	22/18639	0.0909090909090909	0.740907103390706	0.771301490242357	0.972247813851042
GO:0008649	rRNA methyltransferase activity	2/2287	22/18639	0.0909090909090909	0.740907103390706	0.771301490242357	0.972247813851042
GO:0015377	chloride:monoatomic cation symporter activity	2/2287	22/18639	0.0909090909090909	0.740907103390706	0.771301490242357	0.972247813851042
GO:0031683	G-protein beta/gamma-subunit complex binding	2/2287	22/18639	0.0909090909090909	0.740907103390706	0.771301490242357	0.972247813851042
GO:0061133	endopeptidase activator activity	2/2287	22/18639	0.0909090909090909	0.740907103390706	0.771301490242357	0.972247813851042
GO:0070034	telomerase RNA binding	2/2287	22/18639	0.0909090909090909	0.740907103390706	0.771301490242357	0.972247813851042
GO:0140035	ubiquitin-like protein reader activity	2/2287	22/18639	0.0909090909090909	0.740907103390706	0.771301490242357	0.972247813851042
GO:0048487	beta-tubulin binding	4/2287	42/18639	0.0952380952380952	0.776188394028359	0.774595884861053	0.972307318926738
GO:0005249	voltage-gated potassium channel activity	10/2287	98/18639	0.102040816326531	0.831630422173242	0.777602988347697	0.972307318926738
GO:0008170	N-methyltransferase activity	10/2287	98/18639	0.102040816326531	0.831630422173242	0.777602988347697	0.972307318926738
GO:0015616	DNA translocase activity	16/2287	152/18639	0.105263157894737	0.857892435505028	0.779377587880967	0.972307318926738
GO:0140674	ATP-dependent histone chaperone activity	16/2287	152/18639	0.105263157894737	0.857892435505028	0.779377587880967	0.972307318926738
GO:0140299	molecular sensor activity	7/2287	71/18639	0.0985915492957746	0.803518971282879	0.783850315437166	0.972307318926738
GO:0061775	cohesin loader activity	16/2287	153/18639	0.104575163398693	0.852285295403688	0.787980764894482	0.972307318926738
GO:0019239	deaminase activity	3/2287	33/18639	0.0909090909090909	0.740907103390706	0.788181066964159	0.972307318926738
GO:0042923	neuropeptide binding	3/2287	33/18639	0.0909090909090909	0.740907103390706	0.788181066964159	0.972307318926738
GO:0000995	RNA polymerase III general transcription initiation factor activity	1/2287	12/18639	0.0833333333333333	0.679164844774814	0.792238981182944	0.972307318926738
GO:0004126	cytidine deaminase activity	1/2287	12/18639	0.0833333333333333	0.679164844774814	0.792238981182944	0.972307318926738
GO:0004300	enoyl-CoA hydratase activity	1/2287	12/18639	0.0833333333333333	0.679164844774814	0.792238981182944	0.972307318926738
GO:0005095	GTPase inhibitor activity	1/2287	12/18639	0.0833333333333333	0.679164844774814	0.792238981182944	0.972307318926738
GO:0010853	cyclase activator activity	1/2287	12/18639	0.0833333333333333	0.679164844774814	0.792238981182944	0.972307318926738
GO:0015166	polyol transmembrane transporter activity	1/2287	12/18639	0.0833333333333333	0.679164844774814	0.792238981182944	0.972307318926738
GO:0043047	single-stranded telomeric DNA binding	1/2287	12/18639	0.0833333333333333	0.679164844774814	0.792238981182944	0.972307318926738
GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity	1/2287	12/18639	0.0833333333333333	0.679164844774814	0.792238981182944	0.972307318926738
GO:0070410	co-SMAD binding	1/2287	12/18639	0.0833333333333333	0.679164844774814	0.792238981182944	0.972307318926738
GO:0070679	inositol 1,4,5 trisphosphate binding	1/2287	12/18639	0.0833333333333333	0.679164844774814	0.792238981182944	0.972307318926738
GO:0097677	STAT family protein binding	1/2287	12/18639	0.0833333333333333	0.679164844774814	0.792238981182944	0.972307318926738
GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	1/2287	12/18639	0.0833333333333333	0.679164844774814	0.792238981182944	0.972307318926738
GO:0140822	NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity	1/2287	12/18639	0.0833333333333333	0.679164844774814	0.792238981182944	0.972307318926738
GO:0140844	NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity	1/2287	12/18639	0.0833333333333333	0.679164844774814	0.792238981182944	0.972307318926738
GO:0140867	NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity	1/2287	12/18639	0.0833333333333333	0.679164844774814	0.792238981182944	0.972307318926738
GO:0141221	histone deacetylase activity, hydrolytic mechanism	1/2287	12/18639	0.0833333333333333	0.679164844774814	0.792238981182944	0.972307318926738
GO:0008171	O-methyltransferase activity	2/2287	23/18639	0.0869565217391304	0.708693751069371	0.792502235861809	0.972307318926738
GO:0070577	lysine-acetylated histone binding	2/2287	23/18639	0.0869565217391304	0.708693751069371	0.792502235861809	0.972307318926738
GO:0140102	catalytic activity, acting on a rRNA	2/2287	23/18639	0.0869565217391304	0.708693751069371	0.792502235861809	0.972307318926738
GO:0016251	RNA polymerase II general transcription initiation factor activity	5/2287	53/18639	0.0943396226415094	0.768865862009224	0.795191407091113	0.974677467548822
GO:0022824	transmitter-gated monoatomic ion channel activity	6/2287	63/18639	0.0952380952380952	0.776188394028359	0.801128123966411	0.98008735317944
GO:0022835	transmitter-gated channel activity	6/2287	63/18639	0.0952380952380952	0.776188394028359	0.801128123966411	0.98008735317944
GO:0016831	carboxy-lyase activity	3/2287	34/18639	0.0882352941176471	0.719115717996862	0.805043207681422	0.980904951836729
GO:0019825	oxygen binding	3/2287	34/18639	0.0882352941176471	0.719115717996862	0.805043207681422	0.980904951836729
GO:0005230	extracellular ligand-gated monoatomic ion channel activity	7/2287	73/18639	0.0958904109589041	0.781504752891567	0.807533861111736	0.980904951836729
GO:0004806	triacylglycerol lipase activity	2/2287	24/18639	0.0833333333333333	0.679164844774814	0.811946105417712	0.980904951836729
GO:0015295	solute:proton symporter activity	2/2287	24/18639	0.0833333333333333	0.679164844774814	0.811946105417712	0.980904951836729
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	2/2287	24/18639	0.0833333333333333	0.679164844774814	0.811946105417712	0.980904951836729
GO:0019957	C-C chemokine binding	2/2287	24/18639	0.0833333333333333	0.679164844774814	0.811946105417712	0.980904951836729
GO:0140033	acetylation-dependent protein binding	2/2287	24/18639	0.0833333333333333	0.679164844774814	0.811946105417712	0.980904951836729
GO:0140612	DNA damage sensor activity	2/2287	24/18639	0.0833333333333333	0.679164844774814	0.811946105417712	0.980904951836729
GO:0004465	lipoprotein lipase activity	1/2287	13/18639	0.0769230769230769	0.626921395176752	0.817747621867682	0.980904951836729
GO:0004535	poly(A)-specific ribonuclease activity	1/2287	13/18639	0.0769230769230769	0.626921395176752	0.817747621867682	0.980904951836729
GO:0004993	G protein-coupled serotonin receptor activity	1/2287	13/18639	0.0769230769230769	0.626921395176752	0.817747621867682	0.980904951836729
GO:0008417	fucosyltransferase activity	1/2287	13/18639	0.0769230769230769	0.626921395176752	0.817747621867682	0.980904951836729
GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors	1/2287	13/18639	0.0769230769230769	0.626921395176752	0.817747621867682	0.980904951836729
GO:0045159	myosin II binding	1/2287	13/18639	0.0769230769230769	0.626921395176752	0.817747621867682	0.980904951836729
GO:0046974	histone H3K9 methyltransferase activity	1/2287	13/18639	0.0769230769230769	0.626921395176752	0.817747621867682	0.980904951836729
GO:0051011	microtubule minus-end binding	1/2287	13/18639	0.0769230769230769	0.626921395176752	0.817747621867682	0.980904951836729
GO:0052650	all-trans-retinol dehydrogenase (NADP+) activity	1/2287	13/18639	0.0769230769230769	0.626921395176752	0.817747621867682	0.980904951836729
GO:0089720	caspase binding	1/2287	13/18639	0.0769230769230769	0.626921395176752	0.817747621867682	0.980904951836729
GO:0140806	NAD+-protein-aspartate ADP-ribosyltransferase activity	1/2287	13/18639	0.0769230769230769	0.626921395176752	0.817747621867682	0.980904951836729
GO:0031491	nucleosome binding	7/2287	74/18639	0.0945945945945946	0.770943877852492	0.818602639751113	0.980904951836729
GO:0005343	organic acid:sodium symporter activity	3/2287	35/18639	0.0857142857142857	0.698569554625523	0.820759812683402	0.980904951836729
GO:0034061	DNA polymerase activity	3/2287	35/18639	0.0857142857142857	0.698569554625523	0.820759812683402	0.980904951836729
GO:0140566	histone reader activity	3/2287	35/18639	0.0857142857142857	0.698569554625523	0.820759812683402	0.980904951836729
GO:0140767	enzyme-substrate adaptor activity	14/2287	139/18639	0.100719424460432	0.820861107353732	0.820850530791109	0.980904951836729
GO:0016298	lipase activity	13/2287	130/18639	0.1	0.814997813729777	0.821711840137388	0.981023319347698
GO:0004527	exonuclease activity	8/2287	84/18639	0.0952380952380952	0.776188394028359	0.824279386402081	0.981508837783695
GO:0016874	ligase activity	17/2287	167/18639	0.101796407185629	0.829638493018336	0.827227185432727	0.981508837783695
GO:0140658	ATP-dependent chromatin remodeler activity	16/2287	158/18639	0.10126582278481	0.825314241751673	0.827466764003025	0.981508837783695
GO:0000030	mannosyltransferase activity	2/2287	25/18639	0.08	0.651998250983822	0.829744844995074	0.981508837783695
GO:0015662	P-type ion transporter activity	2/2287	25/18639	0.08	0.651998250983822	0.829744844995074	0.981508837783695
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	2/2287	25/18639	0.08	0.651998250983822	0.829744844995074	0.981508837783695
GO:0017025	TBP-class protein binding	2/2287	25/18639	0.08	0.651998250983822	0.829744844995074	0.981508837783695
GO:0019706	protein-cysteine S-palmitoyltransferase activity	2/2287	25/18639	0.08	0.651998250983822	0.829744844995074	0.981508837783695
GO:0019707	protein-cysteine S-acyltransferase activity	2/2287	25/18639	0.08	0.651998250983822	0.829744844995074	0.981508837783695
GO:0140358	P-type transmembrane transporter activity	2/2287	25/18639	0.08	0.651998250983822	0.829744844995074	0.981508837783695
GO:0005231	excitatory extracellular ligand-gated monoatomic ion channel activity	3/2287	36/18639	0.0833333333333333	0.679164844774814	0.83538248225777	0.98213203776776
GO:0016409	palmitoyltransferase activity	3/2287	36/18639	0.0833333333333333	0.679164844774814	0.83538248225777	0.98213203776776
GO:0008276	protein methyltransferase activity	9/2287	95/18639	0.0947368421052632	0.772103191954526	0.839106860321247	0.98213203776776
GO:0051536	iron-sulfur cluster binding	7/2287	76/18639	0.0921052631578947	0.7506558810669	0.839243104171356	0.98213203776776
GO:0005313	L-glutamate transmembrane transporter activity	1/2287	14/18639	0.0714285714285714	0.582141295521269	0.840125544598736	0.98213203776776
GO:0008174	mRNA methyltransferase activity	1/2287	14/18639	0.0714285714285714	0.582141295521269	0.840125544598736	0.98213203776776
GO:0008494	translation activator activity	1/2287	14/18639	0.0714285714285714	0.582141295521269	0.840125544598736	0.98213203776776
GO:0008559	ABC-type xenobiotic transporter activity	1/2287	14/18639	0.0714285714285714	0.582141295521269	0.840125544598736	0.98213203776776
GO:0015926	glucosidase activity	1/2287	14/18639	0.0714285714285714	0.582141295521269	0.840125544598736	0.98213203776776
GO:0043176	amine binding	1/2287	14/18639	0.0714285714285714	0.582141295521269	0.840125544598736	0.98213203776776
GO:0003689	DNA clamp loader activity	16/2287	160/18639	0.1	0.814997813729777	0.841642428500294	0.98213203776776
GO:0005504	fatty acid binding	4/2287	47/18639	0.0851063829787234	0.693615160621087	0.844822888534405	0.98213203776776
GO:0061749	forked DNA-dependent helicase activity	4/2287	47/18639	0.0851063829787234	0.693615160621087	0.844822888534405	0.98213203776776
GO:0099095	ligand-gated monoatomic anion channel activity	4/2287	47/18639	0.0851063829787234	0.693615160621087	0.844822888534405	0.98213203776776
GO:1990518	single-stranded 3'-5' DNA helicase activity	4/2287	47/18639	0.0851063829787234	0.693615160621087	0.844822888534405	0.98213203776776
GO:0004435	phosphatidylinositol phospholipase C activity	2/2287	26/18639	0.0769230769230769	0.626921395176752	0.846009239321854	0.98213203776776
GO:0051540	metal cluster binding	7/2287	77/18639	0.0909090909090909	0.740907103390706	0.848837526594827	0.98213203776776
GO:0022829	wide pore channel activity	3/2287	37/18639	0.0810810810810811	0.660809038159279	0.84896439095091	0.98213203776776
GO:0030551	cyclic nucleotide binding	3/2287	37/18639	0.0810810810810811	0.660809038159279	0.84896439095091	0.98213203776776
GO:0008408	3'-5' exonuclease activity	5/2287	58/18639	0.0862068965517241	0.702584322180842	0.855094868315229	0.98213203776776
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	6/2287	68/18639	0.0882352941176471	0.719115717996862	0.855908577441692	0.98213203776776
GO:0009378	four-way junction helicase activity	4/2287	48/18639	0.0833333333333333	0.679164844774814	0.856406206617843	0.98213203776776
GO:0036121	double-stranded DNA helicase activity	4/2287	48/18639	0.0833333333333333	0.679164844774814	0.856406206617843	0.98213203776776
GO:0043138	3'-5' DNA helicase activity	4/2287	48/18639	0.0833333333333333	0.679164844774814	0.856406206617843	0.98213203776776
GO:0015294	solute:monoatomic cation symporter activity	11/2287	116/18639	0.0948275862068965	0.772842754398926	0.85692999603398	0.98213203776776
GO:0004865	protein serine/threonine phosphatase inhibitor activity	1/2287	15/18639	0.0666666666666667	0.543331875819851	0.859756840142505	0.98213203776776
GO:0005402	carbohydrate:monoatomic cation symporter activity	1/2287	15/18639	0.0666666666666667	0.543331875819851	0.859756840142505	0.98213203776776
GO:0015250	water channel activity	1/2287	15/18639	0.0666666666666667	0.543331875819851	0.859756840142505	0.98213203776776
GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	1/2287	15/18639	0.0666666666666667	0.543331875819851	0.859756840142505	0.98213203776776
GO:0031386	protein tag activity	1/2287	15/18639	0.0666666666666667	0.543331875819851	0.859756840142505	0.98213203776776
GO:0033130	acetylcholine receptor binding	1/2287	15/18639	0.0666666666666667	0.543331875819851	0.859756840142505	0.98213203776776
GO:0042809	nuclear vitamin D receptor binding	1/2287	15/18639	0.0666666666666667	0.543331875819851	0.859756840142505	0.98213203776776
GO:0050780	dopamine receptor binding	1/2287	15/18639	0.0666666666666667	0.543331875819851	0.859756840142505	0.98213203776776
GO:0055105	ubiquitin-protein transferase inhibitor activity	1/2287	15/18639	0.0666666666666667	0.543331875819851	0.859756840142505	0.98213203776776
GO:0140161	monocarboxylate:sodium symporter activity	1/2287	15/18639	0.0666666666666667	0.543331875819851	0.859756840142505	0.98213203776776
GO:0141047	molecular tag activity	1/2287	15/18639	0.0666666666666667	0.543331875819851	0.859756840142505	0.98213203776776
GO:0005044	scavenger receptor activity	2/2287	27/18639	0.0740740740740741	0.603702084244279	0.860847665786711	0.98213203776776
GO:0008266	poly(U) RNA binding	2/2287	27/18639	0.0740740740740741	0.603702084244279	0.860847665786711	0.98213203776776
GO:0008320	protein transmembrane transporter activity	2/2287	27/18639	0.0740740740740741	0.603702084244279	0.860847665786711	0.98213203776776
GO:0005109	frizzled binding	3/2287	38/18639	0.0789473684210526	0.643419326628771	0.861559495446621	0.98213203776776
GO:0042887	amide transmembrane transporter activity	3/2287	38/18639	0.0789473684210526	0.643419326628771	0.861559495446621	0.98213203776776
GO:0016279	protein-lysine N-methyltransferase activity	6/2287	69/18639	0.0869565217391304	0.708693751069371	0.86522791022796	0.984989878176522
GO:0016779	nucleotidyltransferase activity	13/2287	136/18639	0.0955882352941176	0.779042027829934	0.865998287164532	0.984989878176522
GO:0015370	solute:sodium symporter activity	7/2287	79/18639	0.0886075949367089	0.722149961532714	0.866637788705297	0.984989878176522
GO:0016278	lysine N-methyltransferase activity	6/2287	70/18639	0.0857142857142857	0.698569554625523	0.874041167675397	0.984989878176522
GO:0036408	histone H3K14 acetyltransferase activity	2/2287	28/18639	0.0714285714285714	0.582141295521269	0.874365017495444	0.984989878176522
GO:0000062	fatty-acyl-CoA binding	1/2287	16/18639	0.0625	0.509373633581111	0.876978495350521	0.984989878176522
GO:0003688	DNA replication origin binding	1/2287	16/18639	0.0625	0.509373633581111	0.876978495350521	0.984989878176522
GO:0005149	interleukin-1 receptor binding	1/2287	16/18639	0.0625	0.509373633581111	0.876978495350521	0.984989878176522
GO:0005324	long-chain fatty acid transmembrane transporter activity	1/2287	16/18639	0.0625	0.509373633581111	0.876978495350521	0.984989878176522
GO:0017070	U6 snRNA binding	1/2287	16/18639	0.0625	0.509373633581111	0.876978495350521	0.984989878176522
GO:0019841	retinol binding	1/2287	16/18639	0.0625	0.509373633581111	0.876978495350521	0.984989878176522
GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	1/2287	16/18639	0.0625	0.509373633581111	0.876978495350521	0.984989878176522
GO:0043023	ribosomal large subunit binding	1/2287	16/18639	0.0625	0.509373633581111	0.876978495350521	0.984989878176522
GO:0106018	phosphatidylinositol-3,5-bisphosphate phosphatase activity	1/2287	16/18639	0.0625	0.509373633581111	0.876978495350521	0.984989878176522
GO:0015078	proton transmembrane transporter activity	18/2287	185/18639	0.0972972972972973	0.792970845791134	0.881762114597524	0.984989878176522
GO:0004532	RNA exonuclease activity	3/2287	40/18639	0.075	0.611248360297333	0.884005138662947	0.984989878176522
GO:0032451	demethylase activity	3/2287	40/18639	0.075	0.611248360297333	0.884005138662947	0.984989878176522
GO:0071855	neuropeptide receptor binding	3/2287	40/18639	0.075	0.611248360297333	0.884005138662947	0.984989878176522
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	16/2287	167/18639	0.0958083832335329	0.78083622872314	0.884364024152998	0.984989878176522
GO:0004181	metallocarboxypeptidase activity	2/2287	29/18639	0.0689655172413793	0.562067457744674	0.88666192663502	0.984989878176522
GO:0004629	phospholipase C activity	2/2287	29/18639	0.0689655172413793	0.562067457744674	0.88666192663502	0.984989878176522
GO:0010484	histone H3 acetyltransferase activity	2/2287	29/18639	0.0689655172413793	0.562067457744674	0.88666192663502	0.984989878176522
GO:0004540	RNA nuclease activity	11/2287	121/18639	0.0909090909090909	0.740907103390706	0.890442661220611	0.984989878176522
GO:0004549	tRNA-specific ribonuclease activity	1/2287	17/18639	0.0588235294117647	0.479410478664575	0.892086167644639	0.984989878176522
GO:0030548	acetylcholine receptor regulator activity	1/2287	17/18639	0.0588235294117647	0.479410478664575	0.892086167644639	0.984989878176522
GO:0036041	long-chain fatty acid binding	1/2287	17/18639	0.0588235294117647	0.479410478664575	0.892086167644639	0.984989878176522
GO:1901567	fatty acid derivative binding	1/2287	17/18639	0.0588235294117647	0.479410478664575	0.892086167644639	0.984989878176522
GO:0008137	NADH dehydrogenase (ubiquinone) activity	3/2287	41/18639	0.0731707317073171	0.596339863704715	0.893962044624034	0.984989878176522
GO:0042169	SH2 domain binding	3/2287	41/18639	0.0731707317073171	0.596339863704715	0.893962044624034	0.984989878176522
GO:0008528	G protein-coupled peptide receptor activity	11/2287	122/18639	0.0901639344262295	0.73483409434652	0.896308052661621	0.984989878176522
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	11/2287	122/18639	0.0901639344262295	0.73483409434652	0.896308052661621	0.984989878176522
GO:0008106	alcohol dehydrogenase (NADP+) activity	2/2287	30/18639	0.0666666666666667	0.543331875819851	0.897834230713863	0.984989878176522
GO:0008187	poly-pyrimidine tract binding	2/2287	30/18639	0.0666666666666667	0.543331875819851	0.897834230713863	0.984989878176522
GO:0043995	histone H4K5 acetyltransferase activity	2/2287	30/18639	0.0666666666666667	0.543331875819851	0.897834230713863	0.984989878176522
GO:0043996	histone H4K8 acetyltransferase activity	2/2287	30/18639	0.0666666666666667	0.543331875819851	0.897834230713863	0.984989878176522
GO:0043997	histone H4K12 acetyltransferase activity	2/2287	30/18639	0.0666666666666667	0.543331875819851	0.897834230713863	0.984989878176522
GO:0070566	adenylyltransferase activity	2/2287	30/18639	0.0666666666666667	0.543331875819851	0.897834230713863	0.984989878176522
GO:0005179	hormone activity	12/2287	132/18639	0.0909090909090909	0.740907103390706	0.898651482145771	0.984989878176522
GO:0019894	kinesin binding	3/2287	42/18639	0.0714285714285714	0.582141295521269	0.903144056913494	0.984989878176522
GO:0043175	RNA polymerase core enzyme binding	3/2287	42/18639	0.0714285714285714	0.582141295521269	0.903144056913494	0.984989878176522
GO:1901505	carbohydrate derivative transmembrane transporter activity	4/2287	53/18639	0.0754716981132075	0.615092689607379	0.903829274664579	0.984989878176522
GO:0000400	four-way junction DNA binding	1/2287	18/18639	0.0555555555555556	0.452776563183209	0.905339251878164	0.984989878176522
GO:0005372	water transmembrane transporter activity	1/2287	18/18639	0.0555555555555556	0.452776563183209	0.905339251878164	0.984989878176522
GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	1/2287	18/18639	0.0555555555555556	0.452776563183209	0.905339251878164	0.984989878176522
GO:0032393	MHC class I receptor activity	1/2287	18/18639	0.0555555555555556	0.452776563183209	0.905339251878164	0.984989878176522
GO:0034185	apolipoprotein binding	1/2287	18/18639	0.0555555555555556	0.452776563183209	0.905339251878164	0.984989878176522
GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	1/2287	18/18639	0.0555555555555556	0.452776563183209	0.905339251878164	0.984989878176522
GO:0099602	neurotransmitter receptor regulator activity	1/2287	18/18639	0.0555555555555556	0.452776563183209	0.905339251878164	0.984989878176522
GO:0004536	DNA nuclease activity	5/2287	64/18639	0.078125	0.636717041976388	0.90694227720194	0.984989878176522
GO:0005310	dicarboxylic acid transmembrane transporter activity	2/2287	31/18639	0.0645161290322581	0.525805041115985	0.907972633810421	0.984989878176522
GO:0017069	snRNA binding	4/2287	54/18639	0.0740740740740741	0.603702084244279	0.911452746762073	0.984989878176522
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	4/2287	54/18639	0.0740740740740741	0.603702084244279	0.911452746762073	0.984989878176522
GO:0008375	acetylglucosaminyltransferase activity	3/2287	43/18639	0.0697674418604651	0.568603125857984	0.911601091639625	0.984989878176522
GO:0016407	acetyltransferase activity	8/2287	96/18639	0.0833333333333333	0.679164844774814	0.915328805327416	0.984989878176522
GO:0008381	mechanosensitive monoatomic ion channel activity	1/2287	19/18639	0.0526315789473684	0.428946217752514	0.916965326254118	0.984989878176522
GO:0015245	fatty acid transmembrane transporter activity	1/2287	19/18639	0.0526315789473684	0.428946217752514	0.916965326254118	0.984989878176522
GO:0034987	immunoglobulin receptor binding	1/2287	19/18639	0.0526315789473684	0.428946217752514	0.916965326254118	0.984989878176522
GO:0042800	histone H3K4 methyltransferase activity	1/2287	19/18639	0.0526315789473684	0.428946217752514	0.916965326254118	0.984989878176522
GO:0046624	sphingolipid transporter activity	1/2287	19/18639	0.0526315789473684	0.428946217752514	0.916965326254118	0.984989878176522
GO:0099589	serotonin receptor activity	1/2287	19/18639	0.0526315789473684	0.428946217752514	0.916965326254118	0.984989878176522
GO:0120227	acyl-CoA binding	1/2287	19/18639	0.0526315789473684	0.428946217752514	0.916965326254118	0.984989878176522
GO:0003954	NADH dehydrogenase activity	3/2287	44/18639	0.0681818181818182	0.55568032754303	0.919381284953508	0.984989878176522
GO:0030594	neurotransmitter receptor activity	8/2287	97/18639	0.0824742268041237	0.672163145344146	0.920654162518952	0.984989878176522
GO:0140375	immune receptor activity	14/2287	156/18639	0.0897435897435897	0.731408294372877	0.921669145260661	0.984989878176522
GO:0042626	ATPase-coupled transmembrane transporter activity	8/2287	98/18639	0.0816326530612245	0.665304337738593	0.925688265006145	0.984989878176522
GO:0008173	RNA methyltransferase activity	5/2287	67/18639	0.0746268656716418	0.608207323678938	0.92617310119503	0.984989878176522
GO:0001653	peptide receptor activity	11/2287	128/18639	0.0859375	0.700388746174027	0.926279598766556	0.984989878176522
GO:0001614	purinergic nucleotide receptor activity	1/2287	20/18639	0.05	0.407498906864889	0.927164053367804	0.984989878176522
GO:0015464	acetylcholine receptor activity	1/2287	20/18639	0.05	0.407498906864889	0.927164053367804	0.984989878176522
GO:0016502	nucleotide receptor activity	1/2287	20/18639	0.05	0.407498906864889	0.927164053367804	0.984989878176522
GO:0042288	MHC class I protein binding	1/2287	20/18639	0.05	0.407498906864889	0.927164053367804	0.984989878176522
GO:0061608	nuclear import signal receptor activity	1/2287	20/18639	0.05	0.407498906864889	0.927164053367804	0.984989878176522
GO:0140664	ATP-dependent DNA damage sensor activity	1/2287	20/18639	0.05	0.407498906864889	0.927164053367804	0.984989878176522
GO:0140939	histone H4 methyltransferase activity	1/2287	20/18639	0.05	0.407498906864889	0.927164053367804	0.984989878176522
GO:0003727	single-stranded RNA binding	7/2287	89/18639	0.0786516853932584	0.641009516416678	0.93157522217247	0.984989878176522
GO:0140223	general transcription initiation factor activity	5/2287	68/18639	0.0735294117647059	0.599263098330718	0.931749650699263	0.984989878176522
GO:0008175	tRNA methyltransferase activity	2/2287	34/18639	0.0588235294117647	0.479410478664575	0.933011451034527	0.984989878176522
GO:0016891	RNA endonuclease activity, producing 5'-phosphomonoesters	2/2287	34/18639	0.0588235294117647	0.479410478664575	0.933011451034527	0.984989878176522
GO:0016798	hydrolase activity, acting on glycosyl bonds	11/2287	130/18639	0.0846153846153846	0.689613534694427	0.934469492000078	0.984989878176522
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	1/2287	21/18639	0.0476190476190476	0.38809419701418	0.936110603125999	0.984989878176522
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	4/2287	58/18639	0.0689655172413793	0.562067457744674	0.936826591546654	0.984989878176522
GO:0017116	single-stranded DNA helicase activity	4/2287	58/18639	0.0689655172413793	0.562067457744674	0.936826591546654	0.984989878176522
GO:0000049	tRNA binding	6/2287	80/18639	0.075	0.611248360297333	0.938391767737632	0.984989878176522
GO:0061733	protein-lysine-acetyltransferase activity	3/2287	47/18639	0.0638297872340425	0.520211370465815	0.939112314894862	0.984989878176522
GO:0000175	3'-5'-RNA exonuclease activity	2/2287	35/18639	0.0571428571428571	0.465713036417015	0.939814580631564	0.984989878176522
GO:0010485	histone H4 acetyltransferase activity	2/2287	35/18639	0.0571428571428571	0.465713036417015	0.939814580631564	0.984989878176522
GO:0008028	monocarboxylic acid transmembrane transporter activity	5/2287	70/18639	0.0714285714285714	0.582141295521269	0.94178554582729	0.984989878176522
GO:0070063	RNA polymerase binding	4/2287	59/18639	0.0677966101694915	0.552540890664256	0.942040377379595	0.984989878176522
GO:0008970	phospholipase A1 activity	1/2287	22/18639	0.0454545454545455	0.370453551695353	0.943958656120458	0.984989878176522
GO:0032931	histone H3K56 acetyltransferase activity	1/2287	22/18639	0.0454545454545455	0.370453551695353	0.943958656120458	0.984989878176522
GO:0043992	histone H3K9 acetyltransferase activity	1/2287	22/18639	0.0454545454545455	0.370453551695353	0.943958656120458	0.984989878176522
GO:0043993	histone H3K18 acetyltransferase activity	1/2287	22/18639	0.0454545454545455	0.370453551695353	0.943958656120458	0.984989878176522
GO:0043994	histone H3K23 acetyltransferase activity	1/2287	22/18639	0.0454545454545455	0.370453551695353	0.943958656120458	0.984989878176522
GO:0043999	histone H2AK5 acetyltransferase activity	1/2287	22/18639	0.0454545454545455	0.370453551695353	0.943958656120458	0.984989878176522
GO:0044012	histone H2AK9 acetyltransferase activity	1/2287	22/18639	0.0454545454545455	0.370453551695353	0.943958656120458	0.984989878176522
GO:0044014	histone H2BK5 acetyltransferase activity	1/2287	22/18639	0.0454545454545455	0.370453551695353	0.943958656120458	0.984989878176522
GO:0044015	histone H2BK12 acetyltransferase activity	1/2287	22/18639	0.0454545454545455	0.370453551695353	0.943958656120458	0.984989878176522
GO:0044016	histone H3K4 acetyltransferase activity	1/2287	22/18639	0.0454545454545455	0.370453551695353	0.943958656120458	0.984989878176522
GO:0044017	histone H3K27 acetyltransferase activity	1/2287	22/18639	0.0454545454545455	0.370453551695353	0.943958656120458	0.984989878176522
GO:0044018	histone H3K36 acetyltransferase activity	1/2287	22/18639	0.0454545454545455	0.370453551695353	0.943958656120458	0.984989878176522
GO:0046972	histone H4K16 acetyltransferase activity	1/2287	22/18639	0.0454545454545455	0.370453551695353	0.943958656120458	0.984989878176522
GO:0140908	histone H3K122 acetyltransferase activity	1/2287	22/18639	0.0454545454545455	0.370453551695353	0.943958656120458	0.984989878176522
GO:0140098	catalytic activity, acting on RNA	38/2287	387/18639	0.0981912144702842	0.800256251207533	0.944569475590119	0.984989878176522
GO:0008188	neuropeptide receptor activity	3/2287	48/18639	0.0625	0.509373633581111	0.944626055446663	0.984989878176522
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	3/2287	48/18639	0.0625	0.509373633581111	0.944626055446663	0.984989878176522
GO:0000993	RNA polymerase II complex binding	2/2287	36/18639	0.0555555555555556	0.452776563183209	0.945957645241787	0.984989878176522
GO:0004033	aldo-keto reductase (NADPH) activity	2/2287	36/18639	0.0555555555555556	0.452776563183209	0.945957645241787	0.984989878176522
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	4/2287	60/18639	0.0666666666666667	0.543331875819851	0.946858514196686	0.98513088744635
GO:0016917	GABA receptor activity	1/2287	23/18639	0.0434782608695652	0.354346875534686	0.950843038859488	0.987107397344263
GO:0044013	histone H2B acetyltransferase activity	1/2287	23/18639	0.0434782608695652	0.354346875534686	0.950843038859488	0.987107397344263
GO:0008168	methyltransferase activity	18/2287	204/18639	0.0882352941176471	0.719115717996862	0.952258377414003	0.987107397344263
GO:0015399	primary active transmembrane transporter activity	14/2287	166/18639	0.0843373493975904	0.687347553748005	0.954705751544142	0.987107397344263
GO:0016741	transferase activity, transferring one-carbon groups	19/2287	215/18639	0.0883720930232558	0.72023062608678	0.955481662486223	0.987107397344263
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	2/2287	38/18639	0.0526315789473684	0.428946217752514	0.95649681810827	0.987107397344263
GO:0030552	cAMP binding	1/2287	24/18639	0.0416666666666667	0.339582422387407	0.956882035965652	0.987107397344263
GO:0043998	histone H2A acetyltransferase activity	1/2287	24/18639	0.0416666666666667	0.339582422387407	0.956882035965652	0.987107397344263
GO:0070840	dynein complex binding	1/2287	24/18639	0.0416666666666667	0.339582422387407	0.956882035965652	0.987107397344263
GO:0004519	endonuclease activity	10/2287	127/18639	0.078740157480315	0.64173056199195	0.957743870729118	0.987107397344263
GO:0003678	DNA helicase activity	5/2287	74/18639	0.0675675675675676	0.550674198466066	0.957962035184914	0.987107397344263
GO:0003684	damaged DNA binding	5/2287	74/18639	0.0675675675675676	0.550674198466066	0.957962035184914	0.987107397344263
GO:0022853	active monoatomic ion transmembrane transporter activity	9/2287	118/18639	0.076271186440678	0.621608501997288	0.961289769648815	0.98974394683042
GO:0005251	delayed rectifier potassium channel activity	1/2287	25/18639	0.04	0.325999125491911	0.962179418922759	0.989868035294637
GO:0004518	nuclease activity	18/2287	209/18639	0.0861244019138756	0.701911992685932	0.963215321773081	0.990142267669293
GO:0008094	ATP-dependent activity, acting on DNA	18/2287	210/18639	0.0857142857142857	0.698569554625523	0.965120543367537	0.991282614915877
GO:0034212	protein N-acetyltransferase activity	3/2287	53/18639	0.0566037735849057	0.461319517205534	0.965865111969316	0.991282614915877
GO:0008198	ferrous iron binding	1/2287	26/18639	0.0384615384615385	0.313460697588376	0.966826226106795	0.991478368923861
GO:0140318	protein transporter activity	2/2287	41/18639	0.0487804878048781	0.397559909136477	0.968695989726606	0.992604887562215
GO:0015252	proton channel activity	1/2287	27/18639	0.037037037037037	0.30185104212214	0.970902324580645	0.994074217768727
GO:0004402	histone acetyltransferase activity	2/2287	42/18639	0.0476190476190476	0.38809419701418	0.971973586367262	0.994231553346802
GO:0019789	SUMO transferase activity	1/2287	28/18639	0.0357142857142857	0.291070647760635	0.974477780398615	0.994231553346802
GO:0051537	2 iron, 2 sulfur cluster binding	1/2287	28/18639	0.0357142857142857	0.291070647760635	0.974477780398615	0.994231553346802
GO:0170055	lipid transmembrane transporter activity	3/2287	56/18639	0.0535714285714286	0.436605971640952	0.974634732131998	0.994231553346802
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	2/2287	43/18639	0.0465116279069767	0.379068750571989	0.974918586110073	0.994231553346802
GO:0008080	N-acetyltransferase activity	4/2287	69/18639	0.0579710144927536	0.472462500712914	0.976306310703077	0.9948584496238
GO:0061630	ubiquitin protein ligase activity	32/2287	353/18639	0.0906515580736544	0.738808216412262	0.977152359846805	0.994932822090853
GO:0004842	ubiquitin-protein transferase activity	42/2287	449/18639	0.0935412026726058	0.762358756718277	0.97919493221983	0.996224409301914
GO:0140101	catalytic activity, acting on a tRNA	10/2287	139/18639	0.0719424460431655	0.586329362395523	0.981229325165659	0.997505640985942
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	1/2287	32/18639	0.03125	0.254686816790555	0.984894805190897	0.999652692650382
GO:0140142	nucleocytoplasmic carrier activity	1/2287	32/18639	0.03125	0.254686816790555	0.984894805190897	0.999652692650382
GO:1901682	sulfur compound transmembrane transporter activity	3/2287	63/18639	0.0476190476190476	0.38809419701418	0.987523758522378	0.999999999999989
GO:0016229	steroid dehydrogenase activity	1/2287	35/18639	0.0285714285714286	0.232856518208508	0.989808270049146	0.999999999999989
GO:0016755	aminoacyltransferase activity	45/2287	496/18639	0.0907258064516129	0.739413339069354	0.990574592715902	0.999999999999989
GO:0061659	ubiquitin-like protein ligase activity	32/2287	372/18639	0.0860215053763441	0.701073388154647	0.990649981597239	0.999999999999989
GO:0019787	ubiquitin-like protein transferase activity	43/2287	479/18639	0.0897703549060543	0.731626429861804	0.991330484501063	0.999999999999989
GO:0140097	catalytic activity, acting on DNA	28/2287	336/18639	0.0833333333333333	0.679164844774814	0.991993185046276	0.999999999999989
GO:0004812	aminoacyl-tRNA ligase activity	1/2287	41/18639	0.024390243902439	0.198779954568238	0.995361231337679	0.999999999999989
GO:0016875	ligase activity, forming carbon-oxygen bonds	1/2287	41/18639	0.024390243902439	0.198779954568238	0.995361231337679	0.999999999999989
GO:0042287	MHC protein binding	1/2287	41/18639	0.024390243902439	0.198779954568238	0.995361231337679	0.999999999999989
GO:0004520	DNA endonuclease activity	1/2287	42/18639	0.0238095238095238	0.19404709850709	0.995931661702811	0.999999999999989
GO:0031492	nucleosomal DNA binding	1/2287	42/18639	0.0238095238095238	0.19404709850709	0.995931661702811	0.999999999999989
GO:0036002	pre-mRNA binding	2/2287	59/18639	0.0338983050847458	0.276270445332128	0.995947143281414	0.999999999999989
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	4/2287	91/18639	0.043956043956044	0.358240797243858	0.997189795983188	0.999999999999989
GO:0038187	pattern recognition receptor activity	1/2287	48/18639	0.0208333333333333	0.169791211193704	0.998148880951261	0.999999999999989
GO:0003730	mRNA 3'-UTR binding	16/2287	262/18639	0.0610687022900763	0.497708588537268	0.999705658600142	0.999999999999989
GO:0003823	antigen binding	7/2287	174/18639	0.0402298850574713	0.327872683684393	0.999957944427616	0.999999999999989
GO:0003735	structural constituent of ribosome	7/2287	175/18639	0.04	0.325999125491911	0.999961897687593	0.999999999999989
GO:0030371	translation repressor activity	5/2287	329/18639	0.0151975683890578	0.123859850110908	0.999999999999972	0.999999999999989
GO:0045182	translation regulator activity	6/2287	356/18639	0.0168539325842697	0.137359182089288	0.999999999999989	0.999999999999989