ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0003779 actin binding 51/573 443/18639 0.115124153498871 3.74485008213868 3.89382738627961e-16 3.56285205844584e-13 GO:0045296 cadherin binding 38/573 334/18639 0.11377245508982 3.7008809605919 3.70071485093806e-12 1.69307704430416e-09 GO:0008201 heparin binding 22/573 172/18639 0.127906976744186 4.16065992938025 1.62402002423585e-08 4.95326107391933e-06 GO:0051015 actin filament binding 24/573 209/18639 0.114832535885167 3.73536411232746 3.0715592711853e-08 7.02619183283637e-06 GO:0005201 extracellular matrix structural constituent 21/573 168/18639 0.125 4.06609947643979 5.15748902888471e-08 9.43820492285901e-06 GO:0005539 glycosaminoglycan binding 25/573 242/18639 0.103305785123967 3.36041279044611 1.2894214819034e-07 1.96636775990269e-05 GO:0030695 GTPase regulator activity 38/573 489/18639 0.0777096114519427 2.52780008351267 1.72440360502745e-07 2.07752391907973e-05 GO:0060589 nucleoside-triphosphatase regulator activity 38/573 490/18639 0.0775510204081633 2.52264130783203 1.81641435547954e-07 2.07752391907973e-05 GO:1901681 sulfur compound binding 24/573 275/18639 0.0872727272727273 2.83887672536887 4.71893777411106e-06 0.000479758673701291 GO:0005085 guanyl-nucleotide exchange factor activity 21/573 230/18639 0.091304347826087 2.97002048713863 9.23291204932642e-06 0.000844811452513367 GO:0019838 growth factor binding 15/573 136/18639 0.110294117647059 3.58773483215276 1.93601944571936e-05 0.00161041617530292 GO:0005543 phospholipid binding 33/573 497/18639 0.0663983903420523 2.15985968165011 3.06569258776245e-05 0.00233759059816887 GO:0045309 protein phosphorylated amino acid binding 9/573 59/18639 0.152542372881356 4.96201970006212 7.34749065695751e-05 0.00517150303932009 GO:0001784 phosphotyrosine residue binding 8/573 47/18639 0.170212765957447 5.53681630834354 8.29392548950558e-05 0.00542067273064115 GO:0051219 phosphoprotein binding 11/573 93/18639 0.118279569892473 3.84749197770647 0.000131154552606259 0.00800042770898179 GO:0004867 serine-type endopeptidase inhibitor activity 11/573 95/18639 0.115789473684211 3.76649214659686 0.000158963155703667 0.00909070546680346 GO:0035591 signaling adaptor activity 13/573 129/18639 0.10077519379845 3.27809570193596 0.00017304936232299 0.0093141274426786 GO:0031267 small GTPase binding 21/573 283/18639 0.0742049469964664 2.4137975690526 0.000190316893651876 0.00958132846209965 GO:0005520 insulin-like growth factor binding 5/573 19/18639 0.263157894736842 8.56020942408377 0.000219328618293029 0.00958132846209965 GO:0001221 transcription coregulator binding 12/573 115/18639 0.104347826086957 3.39430912815843 0.000219899341753107 0.00958132846209965 GO:0017124 SH3 domain binding 12/573 115/18639 0.104347826086957 3.39430912815843 0.000219899341753107 0.00958132846209965 GO:0001968 fibronectin binding 6/573 30/18639 0.2 6.50575916230367 0.000260134479216007 0.0106558773113527 GO:0141003 histone H2AX kinase activity 24/573 354/18639 0.0677966101694915 2.2053420889165 0.000267852653727992 0.0106558773113527 GO:0140996 histone H3 kinase activity 24/573 357/18639 0.0672268907563025 2.18680980245501 0.000303162425956116 0.0111583949586102 GO:0070325 lipoprotein particle receptor binding 6/573 31/18639 0.193548387096774 6.29589596351968 0.000314263497980314 0.0111583949586102 GO:0051020 GTPase binding 22/573 315/18639 0.0698412698412698 2.27185240588382 0.00031706914636488 0.0111583949586102 GO:0035173 histone kinase activity 24/573 360/18639 0.0666666666666667 2.16858638743456 0.000342511141663946 0.0116073220230559 GO:0010314 phosphatidylinositol-5-phosphate binding 5/573 21/18639 0.238095238095238 7.74495138369484 0.000364773472782859 0.0119202759855827 GO:0004674 protein serine/threonine kinase activity 27/573 433/18639 0.0623556581986143 2.02835447323555 0.000431831132432437 0.0135959624953021 GO:0004866 endopeptidase inhibitor activity 14/573 161/18639 0.0869565217391304 2.82859094013203 0.000460628237545753 0.0135959624953021 GO:0005178 integrin binding 14/573 161/18639 0.0869565217391304 2.82859094013203 0.000460628237545753 0.0135959624953021 GO:0031994 insulin-like growth factor I binding 4/573 13/18639 0.307692307692308 10.0088602496979 0.000506466433941379 0.0140429329411019 GO:0043560 insulin receptor substrate binding 4/573 13/18639 0.307692307692308 10.0088602496979 0.000506466433941379 0.0140429329411019 GO:0032266 phosphatidylinositol-3-phosphate binding 7/573 48/18639 0.145833333333333 4.74378272251309 0.00061662314974103 0.0165944171180307 GO:0005161 platelet-derived growth factor receptor binding 4/573 14/18639 0.285714285714286 9.29394166043381 0.00069189219536522 0.0180880388216907 GO:0030414 peptidase inhibitor activity 14/573 169/18639 0.0828402366863905 2.69469314414945 0.000747447086461584 0.0187563545395529 GO:0005096 GTPase activator activity 19/573 271/18639 0.0701107011070111 2.28061668051235 0.000758453680834379 0.0187563545395529 GO:0042578 phosphoric ester hydrolase activity 23/573 363/18639 0.0633608815426997 2.06105317814028 0.000906164279730841 0.0218194819987821 GO:1990782 protein tyrosine kinase binding 11/573 117/18639 0.094017094017094 3.05826285407437 0.000963950045980251 0.0226157510787674 GO:0050840 extracellular matrix binding 8/573 67/18639 0.119402985074627 3.88403532077831 0.00100512333857645 0.0229921963699362 GO:0055102 lipase inhibitor activity 4/573 16/18639 0.25 8.13219895287958 0.0011979248107537 0.0267341756546252 GO:0004713 protein tyrosine kinase activity 12/573 140/18639 0.0857142857142857 2.78818249813014 0.00130177992694222 0.0283602055512413 GO:0098632 cell-cell adhesion mediator activity 7/573 55/18639 0.127272727272727 4.1400285578296 0.00141254027363772 0.0300575430320585 GO:0046965 nuclear retinoid X receptor binding 4/573 17/18639 0.235294117647059 7.65383430859255 0.00152872492755973 0.0317905297435716 GO:0061135 endopeptidase regulator activity 14/573 184/18639 0.0760869565217391 2.47501707261552 0.00169579103826471 0.0344810844447158 GO:1901981 phosphatidylinositol phosphate binding 14/573 185/18639 0.0756756756756757 2.46163860195274 0.00178433673475768 0.0354927850500712 GO:0106310 protein serine kinase activity 22/573 361/18639 0.0609418282548476 1.98236428768256 0.00189946106988458 0.0365644897845359 GO:0098641 cadherin binding involved in cell-cell adhesion 4/573 18/18639 0.222222222222222 7.22862129144852 0.00191813716902484 0.0365644897845359 GO:0016791 phosphatase activity 18/573 273/18639 0.0659340659340659 2.14475576779242 0.00205011969125468 0.0382828472958782 GO:0001786 phosphatidylserine binding 7/573 59/18639 0.11864406779661 3.85934865560387 0.00213718104001439 0.0385697014713431 GO:0001223 transcription coactivator binding 6/573 44/18639 0.136363636363636 4.43574488338886 0.00214978663938633 0.0385697014713431 GO:1902936 phosphatidylinositol bisphosphate binding 10/573 111/18639 0.0900900900900901 2.93052214518183 0.00222864045066942 0.0392155002377408 GO:0098631 cell adhesion mediator activity 8/573 76/18639 0.105263157894737 3.42408376963351 0.00228488236079737 0.0394465539647092 GO:0070273 phosphatidylinositol-4-phosphate binding 5/573 31/18639 0.161290322580645 5.24657996959973 0.00236415450917565 0.0400592847388097 GO:0019199 transmembrane receptor protein kinase activity 8/573 78/18639 0.102564102564103 3.33628674989932 0.00269375557970302 0.044814297371423 GO:0035401 histone H3Y41 kinase activity 10/573 115/18639 0.0869565217391304 2.82859094013203 0.00289145196450724 0.0464154131144584 GO:0140801 histone H2AXY142 kinase activity 10/573 115/18639 0.0869565217391304 2.82859094013203 0.00289145196450724 0.0464154131144584 GO:0035091 phosphatidylinositol binding 18/573 284/18639 0.0633802816901408 2.0616842415751 0.00313474443661124 0.0486955867024109 GO:0071889 14-3-3 protein binding 5/573 33/18639 0.151515151515152 4.92860542598762 0.0031399340059478 0.0486955867024109 GO:0002020 protease binding 11/573 136/18639 0.0808823529411765 2.63100554357869 0.00321531760451852 0.0490335934689075 GO:0140272 exogenous protein binding 8/573 82/18639 0.0975609756097561 3.17354105478228 0.00368131725182918 0.0552197587774377 GO:0003953 NAD+ nucleosidase activity 3/573 11/18639 0.272727272727273 8.87148976677772 0.0039653724718252 0.0558202432572316 GO:0005536 D-glucose binding 3/573 11/18639 0.272727272727273 8.87148976677772 0.0039653724718252 0.0558202432572316 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding 3/573 11/18639 0.272727272727273 8.87148976677772 0.0039653724718252 0.0558202432572316 GO:0097493 structural molecule activity conferring elasticity 3/573 11/18639 0.272727272727273 8.87148976677772 0.0039653724718252 0.0558202432572316 GO:0005154 epidermal growth factor receptor binding 5/573 35/18639 0.142857142857143 4.6469708302169 0.00408401761918228 0.056619335175027 GO:0004679 AMP-activated protein kinase activity 16/573 248/18639 0.0645161290322581 2.09863198783989 0.00437387726200409 0.0591068973655561 GO:0061134 peptidase regulator activity 15/573 226/18639 0.0663716814159292 2.15899087244591 0.00439264373864242 0.0591068973655561 GO:0005010 insulin-like growth factor receptor activity 6/573 51/18639 0.117647058823529 3.82691715429627 0.00457842213568883 0.0607138587558736 GO:0005158 insulin receptor binding 4/573 23/18639 0.173913043478261 5.65718188026406 0.00491533011011493 0.0627862121187152 GO:0140103 catalytic activity, acting on a glycoprotein 4/573 23/18639 0.173913043478261 5.65718188026406 0.00491533011011493 0.0627862121187152 GO:0030159 signaling receptor complex adaptor activity 6/573 52/18639 0.115384615384615 3.75332259363673 0.00504413266095124 0.0627862121187152 GO:0005078 MAP-kinase scaffold activity 3/573 12/18639 0.25 8.13219895287958 0.00516738442622273 0.0627862121187152 GO:0035259 nuclear glucocorticoid receptor binding 3/573 12/18639 0.25 8.13219895287958 0.00516738442622273 0.0627862121187152 GO:0045295 gamma-catenin binding 3/573 12/18639 0.25 8.13219895287958 0.00516738442622273 0.0627862121187152 GO:0043394 proteoglycan binding 5/573 37/18639 0.135135135135135 4.39578321777275 0.00521502964046159 0.0627862121187152 GO:0017046 peptide hormone binding 6/573 53/18639 0.113207547169811 3.68250518620962 0.00554366893097283 0.0658760658680538 GO:0050699 WW domain binding 4/573 24/18639 0.166666666666667 5.42146596858639 0.00575719455391782 0.0675363207286513 GO:0000146 microfilament motor activity 5/573 38/18639 0.131578947368421 4.28010471204188 0.00585637452486167 0.067830160636056 GO:0019209 kinase activator activity 11/573 148/18639 0.0743243243243243 2.41768076977501 0.00608282229438585 0.0695722799920382 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 5/573 39/18639 0.128205128205128 4.17035843737414 0.00655128363381958 0.0728723007896898 GO:0005172 vascular endothelial growth factor receptor binding 3/573 13/18639 0.230769230769231 7.50664518727346 0.00656565982390714 0.0728723007896898 GO:0042974 nuclear retinoic acid receptor binding 4/573 25/18639 0.16 5.20460732984293 0.00668991613806988 0.0728723007896898 GO:0120020 cholesterol transfer activity 4/573 25/18639 0.16 5.20460732984293 0.00668991613806988 0.0728723007896898 GO:0043178 alcohol binding 8/573 92/18639 0.0869565217391304 2.82859094013203 0.00737424857517929 0.0751755504117085 GO:0048029 monosaccharide binding 7/573 74/18639 0.0945945945945946 3.07704825244092 0.00760910512294941 0.0751755504117085 GO:0005160 transforming growth factor beta receptor binding 4/573 26/18639 0.153846153846154 5.00443012484897 0.00771742726032048 0.0751755504117085 GO:0043548 phosphatidylinositol 3-kinase binding 4/573 26/18639 0.153846153846154 5.00443012484897 0.00771742726032048 0.0751755504117085 GO:0070412 R-SMAD binding 4/573 26/18639 0.153846153846154 5.00443012484897 0.00771742726032048 0.0751755504117085 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 5/573 41/18639 0.121951219512195 3.96692631847784 0.00811058248000881 0.0751755504117085 GO:0044548 S100 protein binding 3/573 14/18639 0.214285714285714 6.97045624532536 0.0081675964498731 0.0751755504117085 GO:0042562 hormone binding 8/573 94/18639 0.0851063829787234 2.76840815417177 0.00836447902307562 0.0751755504117085 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 15/573 243/18639 0.0617283950617284 2.0079503587357 0.00841597846944053 0.0751755504117085 GO:0004676 3-phosphoinositide-dependent protein kinase activity 15/573 245/18639 0.0612244897959184 1.99155892723582 0.00903749786370266 0.0751755504117085 GO:0004711 ribosomal protein S6 kinase activity 15/573 245/18639 0.0612244897959184 1.99155892723582 0.00903749786370266 0.0751755504117085 GO:0035175 histone H3S10 kinase activity 15/573 245/18639 0.0612244897959184 1.99155892723582 0.00903749786370266 0.0751755504117085 GO:0035979 histone H2AXS139 kinase activity 15/573 245/18639 0.0612244897959184 1.99155892723582 0.00903749786370266 0.0751755504117085 GO:0044022 histone H3S28 kinase activity 15/573 245/18639 0.0612244897959184 1.99155892723582 0.00903749786370266 0.0751755504117085 GO:0044023 histone H4S1 kinase activity 15/573 245/18639 0.0612244897959184 1.99155892723582 0.00903749786370266 0.0751755504117085 GO:0044024 histone H2AS1 kinase activity 15/573 245/18639 0.0612244897959184 1.99155892723582 0.00903749786370266 0.0751755504117085 GO:0044025 histone H2BS14 kinase activity 15/573 245/18639 0.0612244897959184 1.99155892723582 0.00903749786370266 0.0751755504117085 GO:0072354 histone H3T3 kinase activity 15/573 245/18639 0.0612244897959184 1.99155892723582 0.00903749786370266 0.0751755504117085 GO:0072371 histone H2AS121 kinase activity 15/573 245/18639 0.0612244897959184 1.99155892723582 0.00903749786370266 0.0751755504117085 GO:0072518 Rho-dependent protein serine/threonine kinase activity 15/573 245/18639 0.0612244897959184 1.99155892723582 0.00903749786370266 0.0751755504117085 GO:0140823 histone H2BS36 kinase activity 15/573 245/18639 0.0612244897959184 1.99155892723582 0.00903749786370266 0.0751755504117085 GO:0140855 histone H3S57 kinase activity 15/573 245/18639 0.0612244897959184 1.99155892723582 0.00903749786370266 0.0751755504117085 GO:0140995 histone H2A kinase activity 15/573 245/18639 0.0612244897959184 1.99155892723582 0.00903749786370266 0.0751755504117085 GO:0140997 histone H4 kinase activity 15/573 245/18639 0.0612244897959184 1.99155892723582 0.00903749786370266 0.0751755504117085 GO:0140998 histone H2B kinase activity 15/573 245/18639 0.0612244897959184 1.99155892723582 0.00903749786370266 0.0751755504117085 GO:1990244 histone H2AT120 kinase activity 15/573 245/18639 0.0612244897959184 1.99155892723582 0.00903749786370266 0.0751755504117085 GO:0004677 DNA-dependent protein kinase activity 15/573 246/18639 0.0609756097560976 1.98346315923892 0.00936161250546334 0.0764810307365978 GO:0140857 histone H3T45 kinase activity 15/573 246/18639 0.0609756097560976 1.98346315923892 0.00936161250546334 0.0764810307365978 GO:0035402 histone H3T11 kinase activity 15/573 247/18639 0.0607287449392713 1.97543294401933 0.00969485955700449 0.077814004339115 GO:0035403 histone H3T6 kinase activity 15/573 247/18639 0.0607287449392713 1.97543294401933 0.00969485955700449 0.077814004339115 GO:0004857 enzyme inhibitor activity 22/573 416/18639 0.0528846153846154 1.72027285541683 0.00992438385154005 0.0789635758622535 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 4/573 28/18639 0.142857142857143 4.6469708302169 0.0100715053060869 0.0790094167455108 GO:0004714 transmembrane receptor protein tyrosine kinase activity 6/573 60/18639 0.1 3.25287958115183 0.0101028434527047 0.0790094167455108 GO:0004725 protein tyrosine phosphatase activity 8/573 98/18639 0.0816326530612245 2.65541190298109 0.0106394724352871 0.0823774789303731 GO:0030295 protein kinase activator activity 10/573 139/18639 0.0719424460431655 2.3402011375193 0.0108036037941473 0.0823774789303731 GO:0070851 growth factor receptor binding 10/573 139/18639 0.0719424460431655 2.3402011375193 0.0108036037941473 0.0823774789303731 GO:0030020 extracellular matrix structural constituent conferring tensile strength 5/573 44/18639 0.113636363636364 3.69645406949072 0.0109049412772434 0.0824629856915513 GO:0003785 actin monomer binding 4/573 29/18639 0.137931034482759 4.48673045676115 0.0114048723120517 0.0848411232969698 GO:0004629 phospholipase C activity 4/573 29/18639 0.137931034482759 4.48673045676115 0.0114048723120517 0.0848411232969698 GO:0004715 non-membrane spanning protein tyrosine kinase activity 5/573 45/18639 0.111111111111111 3.61431064572426 0.0119659064066912 0.0864985020227732 GO:0005159 insulin-like growth factor receptor binding 3/573 16/18639 0.1875 6.09914921465969 0.0120058030129969 0.0864985020227732 GO:0061809 NAD+ nucleosidase activity, cyclic ADP-ribose generating 3/573 16/18639 0.1875 6.09914921465969 0.0120058030129969 0.0864985020227732 GO:0070411 I-SMAD binding 3/573 16/18639 0.1875 6.09914921465969 0.0120058030129969 0.0864985020227732 GO:0001618 virus receptor activity 7/573 81/18639 0.0864197530864197 2.81113050222998 0.0122522072209311 0.0875841375558746 GO:0001540 amyloid-beta binding 7/573 83/18639 0.0843373493975904 2.74339241783889 0.0138889354115179 0.0985145418723945 GO:0071813 lipoprotein particle binding 4/573 32/18639 0.125 4.06609947643979 0.0160663465181267 0.106687917571409 GO:0071814 protein-lipid complex binding 4/573 32/18639 0.125 4.06609947643979 0.0160663465181267 0.106687917571409 GO:0120015 sterol transfer activity 4/573 32/18639 0.125 4.06609947643979 0.0160663465181267 0.106687917571409 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 7/573 86/18639 0.0813953488372093 2.64769268233289 0.0166287996689892 0.106687917571409 GO:0001222 transcription corepressor binding 5/573 49/18639 0.102040816326531 3.31926487872636 0.0169068284676003 0.106687917571409 GO:0005004 GPI-linked ephrin receptor activity 5/573 49/18639 0.102040816326531 3.31926487872636 0.0169068284676003 0.106687917571409 GO:0005008 hepatocyte growth factor receptor activity 5/573 49/18639 0.102040816326531 3.31926487872636 0.0169068284676003 0.106687917571409 GO:0005009 insulin receptor activity 5/573 49/18639 0.102040816326531 3.31926487872636 0.0169068284676003 0.106687917571409 GO:0005011 macrophage colony-stimulating factor receptor activity 5/573 49/18639 0.102040816326531 3.31926487872636 0.0169068284676003 0.106687917571409 GO:0005018 platelet-derived growth factor alpha-receptor activity 5/573 49/18639 0.102040816326531 3.31926487872636 0.0169068284676003 0.106687917571409 GO:0005020 stem cell factor receptor activity 5/573 49/18639 0.102040816326531 3.31926487872636 0.0169068284676003 0.106687917571409 GO:0008288 boss receptor activity 5/573 49/18639 0.102040816326531 3.31926487872636 0.0169068284676003 0.106687917571409 GO:0035254 glutamate receptor binding 5/573 49/18639 0.102040816326531 3.31926487872636 0.0169068284676003 0.106687917571409 GO:0036332 placental growth factor receptor activity 5/573 49/18639 0.102040816326531 3.31926487872636 0.0169068284676003 0.106687917571409 GO:0038062 protein tyrosine kinase collagen receptor activity 5/573 49/18639 0.102040816326531 3.31926487872636 0.0169068284676003 0.106687917571409 GO:0060175 brain-derived neurotrophic factor receptor activity 5/573 49/18639 0.102040816326531 3.31926487872636 0.0169068284676003 0.106687917571409 GO:0030296 protein tyrosine kinase activator activity 4/573 33/18639 0.121212121212121 3.9428843407901 0.0178492999680824 0.111781233511129 GO:0005006 epidermal growth factor receptor activity 5/573 50/18639 0.1 3.25287958115183 0.0183247923788737 0.111781233511129 GO:0005007 fibroblast growth factor receptor activity 5/573 50/18639 0.1 3.25287958115183 0.0183247923788737 0.111781233511129 GO:0005017 platelet-derived growth factor receptor activity 5/573 50/18639 0.1 3.25287958115183 0.0183247923788737 0.111781233511129 GO:0005019 platelet-derived growth factor beta-receptor activity 5/573 50/18639 0.1 3.25287958115183 0.0183247923788737 0.111781233511129 GO:0042577 lipid phosphatase activity 3/573 19/18639 0.157894736842105 5.13612565445026 0.0194073711988088 0.116245841010223 GO:0004721 phosphoprotein phosphatase activity 11/573 175/18639 0.0628571428571429 2.04466716529544 0.0196358354519286 0.116245841010223 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 7/573 89/18639 0.0786516853932584 2.55844461438908 0.0197303233476495 0.116245841010223 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 7/573 89/18639 0.0786516853932584 2.55844461438908 0.0197303233476495 0.116245841010223 GO:0005021 vascular endothelial growth factor receptor activity 5/573 51/18639 0.0980392156862745 3.18909762858023 0.0198189630574807 0.116245841010223 GO:0005030 neurotrophin receptor activity 5/573 51/18639 0.0980392156862745 3.18909762858023 0.0198189630574807 0.116245841010223 GO:0140793 histone H2AXY142 phosphatase activity 7/573 90/18639 0.0777777777777778 2.53001745200698 0.020848241321489 0.121413484581986 GO:0033218 amide binding 14/573 247/18639 0.0566801619433198 1.84373741441804 0.0209653885944849 0.121413484581986 GO:0072341 modified amino acid binding 7/573 91/18639 0.0769230769230769 2.50221506242449 0.0220094621183487 0.126658225398044 GO:0031418 L-ascorbic acid binding 3/573 20/18639 0.15 4.87931937172775 0.0223217302916256 0.127652395105234 GO:0005003 ephrin receptor activity 5/573 53/18639 0.0943396226415094 3.06875432184135 0.0230414915037616 0.129343341876944 GO:0005005 transmembrane-ephrin receptor activity 5/573 53/18639 0.0943396226415094 3.06875432184135 0.0230414915037616 0.129343341876944 GO:0038064 collagen receptor activity 5/573 53/18639 0.0943396226415094 3.06875432184135 0.0230414915037616 0.129343341876944 GO:0005518 collagen binding 6/573 72/18639 0.0833333333333333 2.71073298429319 0.0232267306628963 0.129588161930183 GO:0015485 cholesterol binding 5/573 54/18639 0.0925925925925926 3.01192553810355 0.0247724178270448 0.137374317040885 GO:0016922 nuclear receptor binding 9/573 137/18639 0.0656934306569343 2.13692819199755 0.0257478933462103 0.141923628986641 GO:0030246 carbohydrate binding 15/573 280/18639 0.0535714285714286 1.74261406133134 0.0269759097945193 0.147802140490929 GO:0043531 ADP binding 4/573 38/18639 0.105263157894737 3.42408376963351 0.0285734295964367 0.155623143337736 GO:0005283 amino acid:sodium symporter activity 3/573 23/18639 0.130434782608696 4.24288641019804 0.0324103274536842 0.173423681989012 GO:0017134 fibroblast growth factor binding 3/573 23/18639 0.130434782608696 4.24288641019804 0.0324103274536842 0.173423681989012 GO:0099186 structural constituent of postsynapse 3/573 23/18639 0.130434782608696 4.24288641019804 0.0324103274536842 0.173423681989012 GO:0030331 nuclear estrogen receptor binding 4/573 40/18639 0.1 3.25287958115183 0.0337333886639899 0.178416477615901 GO:0071949 FAD binding 4/573 40/18639 0.1 3.25287958115183 0.0337333886639899 0.178416477615901 GO:0019955 cytokine binding 9/573 144/18639 0.0625 2.0330497382199 0.0339667204212375 0.178618098766852 GO:0046332 SMAD binding 6/573 79/18639 0.0759493670886076 2.47054145403937 0.0346197182514788 0.181011669714875 GO:0008194 UDP-glycosyltransferase activity 9/573 145/18639 0.0620689655172414 2.01902870554252 0.0352729038852208 0.182084587083307 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity 2/573 10/18639 0.2 6.50575916230367 0.0360493890581418 0.182084587083307 GO:0004445 inositol-polyphosphate 5-phosphatase activity 2/573 10/18639 0.2 6.50575916230367 0.0360493890581418 0.182084587083307 GO:0004862 cAMP-dependent protein kinase inhibitor activity 2/573 10/18639 0.2 6.50575916230367 0.0360493890581418 0.182084587083307 GO:0030552 cAMP binding 3/573 24/18639 0.125 4.06609947643979 0.0362179178679365 0.182084587083307 GO:0050431 transforming growth factor beta binding 3/573 24/18639 0.125 4.06609947643979 0.0362179178679365 0.182084587083307 GO:0070300 phosphatidic acid binding 3/573 24/18639 0.125 4.06609947643979 0.0362179178679365 0.182084587083307 GO:0001727 lipid kinase activity 4/573 41/18639 0.0975609756097561 3.17354105478228 0.0365034217649608 0.182517108824804 GO:0030971 receptor tyrosine kinase binding 6/573 81/18639 0.0740740740740741 2.40954043048284 0.0384346888746913 0.191129023480122 GO:0019894 kinesin binding 4/573 42/18639 0.0952380952380952 3.09798055347794 0.0394007027372692 0.194873745970818 GO:0008200 ion channel inhibitor activity 4/573 43/18639 0.0930232558139535 3.02593449409473 0.0424253863676431 0.204709539002163 GO:0008375 acetylglucosaminyltransferase activity 4/573 43/18639 0.0930232558139535 3.02593449409473 0.0424253863676431 0.204709539002163 GO:0008432 JUN kinase binding 2/573 11/18639 0.181818181818182 5.91432651118515 0.0431791705217677 0.204709539002163 GO:0016176 superoxide-generating NADPH oxidase activator activity 2/573 11/18639 0.181818181818182 5.91432651118515 0.0431791705217677 0.204709539002163 GO:0032050 clathrin heavy chain binding 2/573 11/18639 0.181818181818182 5.91432651118515 0.0431791705217677 0.204709539002163 GO:0032794 GTPase activating protein binding 2/573 11/18639 0.181818181818182 5.91432651118515 0.0431791705217677 0.204709539002163 GO:0048185 activin binding 2/573 11/18639 0.181818181818182 5.91432651118515 0.0431791705217677 0.204709539002163 GO:0070697 activin receptor binding 2/573 11/18639 0.181818181818182 5.91432651118515 0.0431791705217677 0.204709539002163 GO:0031490 chromatin DNA binding 8/573 128/18639 0.0625 2.0330497382199 0.0440789440796846 0.206627996076829 GO:0004435 phosphatidylinositol phospholipase C activity 3/573 26/18639 0.115384615384615 3.75332259363673 0.0444871204668145 0.206627996076829 GO:0050750 low-density lipoprotein particle receptor binding 3/573 26/18639 0.115384615384615 3.75332259363673 0.0444871204668145 0.206627996076829 GO:0052742 phosphatidylinositol kinase activity 3/573 26/18639 0.115384615384615 3.75332259363673 0.0444871204668145 0.206627996076829 GO:0008013 beta-catenin binding 7/573 106/18639 0.0660377358490566 2.14812802528895 0.045065895883628 0.208259064310705 GO:0016248 channel inhibitor activity 4/573 44/18639 0.0909090909090909 2.95716325559258 0.0455774308766831 0.209564569106357 GO:0003774 cytoskeletal motor activity 9/573 153/18639 0.0588235294117647 1.91345857714814 0.0469774435196576 0.214921804102433 GO:0031625 ubiquitin protein ligase binding 15/573 302/18639 0.0496688741721854 1.61566866613502 0.0472485042413298 0.215086474531427 GO:0005319 lipid transporter activity 10/573 178/18639 0.0561797752808989 1.82746043884934 0.0487115139931773 0.218145999450245 GO:0141110 transporter inhibitor activity 4/573 45/18639 0.0888888888888889 2.89144851657941 0.0488566039957066 0.218145999450245 GO:0004683 calcium/calmodulin-dependent protein kinase activity 3/573 27/18639 0.111111111111111 3.61431064572426 0.048942578846205 0.218145999450245 GO:0035255 ionotropic glutamate receptor binding 3/573 27/18639 0.111111111111111 3.61431064572426 0.048942578846205 0.218145999450245 GO:0120013 lipid transfer activity 5/573 65/18639 0.0769230769230769 2.50221506242449 0.049370158899041 0.218145999450245 GO:0004859 phospholipase inhibitor activity 2/573 12/18639 0.166666666666667 5.42146596858639 0.0507815277408767 0.218145999450245 GO:0005527 macrolide binding 2/573 12/18639 0.166666666666667 5.42146596858639 0.0507815277408767 0.218145999450245 GO:0008603 cAMP-dependent protein kinase regulator activity 2/573 12/18639 0.166666666666667 5.42146596858639 0.0507815277408767 0.218145999450245 GO:0017166 vinculin binding 2/573 12/18639 0.166666666666667 5.42146596858639 0.0507815277408767 0.218145999450245 GO:0035497 cAMP response element binding 2/573 12/18639 0.166666666666667 5.42146596858639 0.0507815277408767 0.218145999450245 GO:0106019 phosphatidylinositol-4,5-bisphosphate phosphatase activity 2/573 12/18639 0.166666666666667 5.42146596858639 0.0507815277408767 0.218145999450245 GO:1990247 N6-methyladenosine-containing RNA reader activity 2/573 12/18639 0.166666666666667 5.42146596858639 0.0507815277408767 0.218145999450245 GO:0005179 hormone activity 8/573 132/18639 0.0606060606060606 1.97144217039505 0.0511801821944579 0.21883115284079 GO:0004222 metalloendopeptidase activity 7/573 110/18639 0.0636363636363636 2.0700142789148 0.0531310105643409 0.226039186723422 GO:0003713 transcription coactivator activity 13/573 256/18639 0.05078125 1.65185291230366 0.0535984024119903 0.226039186723422 GO:0045499 chemorepellent activity 3/573 28/18639 0.107142857142857 3.48522812266268 0.0536071076710192 0.226039186723422 GO:0016500 protein-hormone receptor activity 5/573 67/18639 0.0746268656716418 2.42752207548644 0.0549727697252554 0.230734331644994 GO:0005516 calmodulin binding 11/573 207/18639 0.0531400966183575 1.72858335230291 0.0555581230046865 0.232126404334649 GO:0032934 sterol binding 5/573 68/18639 0.0735294117647059 2.39182322143517 0.0579062486278368 0.237286495984879 GO:0005416 amino acid:monoatomic cation symporter activity 3/573 29/18639 0.103448275862069 3.36504784257086 0.0584765963662847 0.237286495984879 GO:0008035 high-density lipoprotein particle binding 2/573 13/18639 0.153846153846154 5.00443012484897 0.058820776453053 0.237286495984879 GO:0045159 myosin II binding 2/573 13/18639 0.153846153846154 5.00443012484897 0.058820776453053 0.237286495984879 GO:0086080 protein binding involved in heterotypic cell-cell adhesion 2/573 13/18639 0.153846153846154 5.00443012484897 0.058820776453053 0.237286495984879 GO:0140410 monoatomic cation:bicarbonate symporter activity 2/573 13/18639 0.153846153846154 5.00443012484897 0.058820776453053 0.237286495984879 GO:0044325 transmembrane transporter binding 8/573 136/18639 0.0588235294117647 1.91345857714814 0.0589806684604722 0.237286495984879 GO:0140789 histone phosphatase activity 8/573 136/18639 0.0588235294117647 1.91345857714814 0.0589806684604722 0.237286495984879 GO:0099106 ion channel regulator activity 9/573 160/18639 0.05625 1.82974476439791 0.0591271268683633 0.237286495984879 GO:0031210 phosphatidylcholine binding 3/573 30/18639 0.1 3.25287958115183 0.0635465939896554 0.252285775258579 GO:0098918 structural constituent of synapse 3/573 30/18639 0.1 3.25287958115183 0.0635465939896554 0.252285775258579 GO:0031406 carboxylic acid binding 10/573 187/18639 0.053475935828877 1.7395077974074 0.0636918186718379 0.252285775258579 GO:0097110 scaffold protein binding 5/573 70/18639 0.0714285714285714 2.32348541510845 0.0640370657534881 0.252559979157076 GO:0015294 solute:monoatomic cation symporter activity 7/573 116/18639 0.0603448275862069 1.962944574833 0.0668266881164958 0.259055334493772 GO:0008191 metalloendopeptidase inhibitor activity 2/573 14/18639 0.142857142857143 4.6469708302169 0.0672629731202496 0.259055334493772 GO:0034236 protein kinase A catalytic subunit binding 2/573 14/18639 0.142857142857143 4.6469708302169 0.0672629731202496 0.259055334493772 GO:0034595 phosphatidylinositol phosphate 5-phosphatase activity 2/573 14/18639 0.142857142857143 4.6469708302169 0.0672629731202496 0.259055334493772 GO:0046030 inositol trisphosphate phosphatase activity 2/573 14/18639 0.142857142857143 4.6469708302169 0.0672629731202496 0.259055334493772 GO:0043177 organic acid binding 10/573 189/18639 0.0529100529100529 1.72110030748774 0.0673826990267954 0.259055334493772 GO:0044389 ubiquitin-like protein ligase binding 15/573 322/18639 0.046583850931677 1.51531657507073 0.0733461318500018 0.280802136580551 GO:0016247 channel regulator activity 9/573 168/18639 0.0535714285714286 1.74261406133134 0.0752849668687009 0.284119981089415 GO:0004896 cytokine receptor activity 6/573 96/18639 0.0625 2.0330497382199 0.0754391920647224 0.284119981089415 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 2/573 15/18639 0.133333333333333 4.33717277486911 0.0760758419310455 0.284119981089415 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 2/573 15/18639 0.133333333333333 4.33717277486911 0.0760758419310455 0.284119981089415 GO:0047372 monoacylglycerol lipase activity 2/573 15/18639 0.133333333333333 4.33717277486911 0.0760758419310455 0.284119981089415 GO:0120283 protein serine/threonine kinase binding 2/573 15/18639 0.133333333333333 4.33717277486911 0.0760758419310455 0.284119981089415 GO:0140297 DNA-binding transcription factor binding 21/573 488/18639 0.0430327868852459 1.39980473779075 0.0770666255408452 0.286650253536071 GO:0005544 calcium-dependent phospholipid binding 4/573 53/18639 0.0754716981132075 2.45500345747308 0.0795810286646432 0.292908540152375 GO:0051018 protein kinase A binding 4/573 53/18639 0.0754716981132075 2.45500345747308 0.0795810286646432 0.292908540152375 GO:0141108 transporter regulator activity 9/573 170/18639 0.0529411764705882 1.72211271943332 0.0797095371562202 0.292908540152375 GO:0015293 symporter activity 8/573 146/18639 0.0547945205479452 1.78239977049415 0.0816100850378164 0.298692911238408 GO:0005126 cytokine receptor binding 13/573 275/18639 0.0472727272727273 1.53772489290814 0.0833363388175244 0.300557297980674 GO:0016758 hexosyltransferase activity 10/573 197/18639 0.050761421319797 1.65120790921413 0.08348967654893 0.300557297980674 GO:0042277 peptide binding 12/573 249/18639 0.0481927710843374 1.56765281019365 0.0839457183834331 0.300557297980674 GO:0008017 microtubule binding 13/573 276/18639 0.0471014492753623 1.53215342590485 0.0851428194855465 0.300557297980674 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 2/573 16/18639 0.125 4.06609947643979 0.0852287046336239 0.300557297980674 GO:0005024 transforming growth factor beta receptor activity 2/573 16/18639 0.125 4.06609947643979 0.0852287046336239 0.300557297980674 GO:0022858 alanine transmembrane transporter activity 2/573 16/18639 0.125 4.06609947643979 0.0852287046336239 0.300557297980674 GO:0031435 mitogen-activated protein kinase kinase kinase binding 2/573 16/18639 0.125 4.06609947643979 0.0852287046336239 0.300557297980674 GO:0034450 ubiquitin-ubiquitin ligase activity 2/573 16/18639 0.125 4.06609947643979 0.0852287046336239 0.300557297980674 GO:0051427 hormone receptor binding 3/573 34/18639 0.0882352941176471 2.87018786572221 0.0857327374567824 0.300557297980674 GO:0052866 phosphatidylinositol phosphate phosphatase activity 3/573 34/18639 0.0882352941176471 2.87018786572221 0.0857327374567824 0.300557297980674 GO:0003712 transcription coregulator activity 21/573 495/18639 0.0424242424242424 1.38000951927653 0.0861815225695822 0.300977454775449 GO:0005343 organic acid:sodium symporter activity 3/573 35/18639 0.0857142857142857 2.78818249813014 0.0917290508279593 0.317924551165086 GO:0061631 ubiquitin conjugating enzyme activity 3/573 35/18639 0.0857142857142857 2.78818249813014 0.0917290508279593 0.317924551165086 GO:0030169 low-density lipoprotein particle binding 2/573 17/18639 0.117647058823529 3.82691715429627 0.0946924130948855 0.32450770779708 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 2/573 17/18639 0.117647058823529 3.82691715429627 0.0946924130948855 0.32450770779708 GO:0036041 long-chain fatty acid binding 2/573 17/18639 0.117647058823529 3.82691715429627 0.0946924130948855 0.32450770779708 GO:0019887 protein kinase regulator activity 12/573 255/18639 0.0470588235294118 1.53076686171851 0.0958432799774193 0.326218118924574 GO:0015370 solute:sodium symporter activity 5/573 79/18639 0.0632911392405063 2.05878454503281 0.0959045617384812 0.326218118924574 GO:0030551 cyclic nucleotide binding 3/573 37/18639 0.0810810810810811 2.63746993066365 0.104221432745216 0.350043755690973 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 2/573 18/18639 0.111111111111111 3.61431064572426 0.104439284484848 0.350043755690973 GO:0015172 acidic amino acid transmembrane transporter activity 2/573 18/18639 0.111111111111111 3.61431064572426 0.104439284484848 0.350043755690973 GO:0070064 proline-rich region binding 2/573 18/18639 0.111111111111111 3.61431064572426 0.104439284484848 0.350043755690973 GO:0016798 hydrolase activity, acting on glycosyl bonds 7/573 130/18639 0.0538461538461538 1.75155054369714 0.106300507060143 0.354803855698452 GO:0019207 kinase regulator activity 13/573 287/18639 0.0452961672473868 1.47342977543463 0.106635038597895 0.354803855698452 GO:0015459 potassium channel regulator activity 4/573 59/18639 0.0677966101694915 2.2053420889165 0.107586619638152 0.356673032496048 GO:0005501 retinoid binding 3/573 38/18639 0.0789473684210526 2.56806282722513 0.110705547300826 0.364372574749121 GO:0019840 isoprenoid binding 3/573 38/18639 0.0789473684210526 2.56806282722513 0.110705547300826 0.364372574749121 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 20/573 484/18639 0.0413223140495868 1.34416511617844 0.111749904673269 0.364861953571481 GO:0030165 PDZ domain binding 5/573 83/18639 0.0602409638554217 1.95956601274207 0.112228005094013 0.364861953571481 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 4/573 60/18639 0.0666666666666667 2.16858638743456 0.112635650519532 0.364861953571481 GO:0003756 protein disulfide isomerase activity 2/573 19/18639 0.105263157894737 3.42408376963351 0.114443038989087 0.364861953571481 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 2/573 19/18639 0.105263157894737 3.42408376963351 0.114443038989087 0.364861953571481 GO:0008574 plus-end-directed microtubule motor activity 2/573 19/18639 0.105263157894737 3.42408376963351 0.114443038989087 0.364861953571481 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 2/573 19/18639 0.105263157894737 3.42408376963351 0.114443038989087 0.364861953571481 GO:0016918 retinal binding 2/573 19/18639 0.105263157894737 3.42408376963351 0.114443038989087 0.364861953571481 GO:0140036 ubiquitin-modified protein reader activity 2/573 19/18639 0.105263157894737 3.42408376963351 0.114443038989087 0.364861953571481 GO:0008237 metallopeptidase activity 9/573 184/18639 0.0489130434782609 1.59108240382427 0.11499488609539 0.36534833603223 GO:0016757 glycosyltransferase activity 12/573 267/18639 0.0449438202247191 1.46196835107948 0.12254993826051 0.388004129786736 GO:0015179 L-amino acid transmembrane transporter activity 4/573 62/18639 0.0645161290322581 2.09863198783989 0.123040176717783 0.388030772310398 GO:0001216 DNA-binding transcription activator activity 20/573 491/18639 0.0407331975560081 1.32500186604963 0.123620058855962 0.388030772310398 GO:0050997 quaternary ammonium group binding 3/573 40/18639 0.075 2.43965968586387 0.124119082777952 0.388030772310398 GO:0015095 magnesium ion transmembrane transporter activity 2/573 20/18639 0.1 3.25287958115183 0.124678739955472 0.388030772310398 GO:0052745 inositol phosphate phosphatase activity 2/573 20/18639 0.1 3.25287958115183 0.124678739955472 0.388030772310398 GO:0008081 phosphoric diester hydrolase activity 5/573 87/18639 0.0574712643678161 1.86947102365048 0.129791794511341 0.402342414135468 GO:0015175 neutral L-amino acid transmembrane transporter activity 3/573 41/18639 0.0731707317073171 2.38015579108671 0.131036108647398 0.402342414135468 GO:0042169 SH2 domain binding 3/573 41/18639 0.0731707317073171 2.38015579108671 0.131036108647398 0.402342414135468 GO:0061650 ubiquitin-like protein conjugating enzyme activity 3/573 41/18639 0.0731707317073171 2.38015579108671 0.131036108647398 0.402342414135468 GO:0019902 phosphatase binding 9/573 190/18639 0.0473684210526316 1.54083769633508 0.132380551477489 0.405111052180276 GO:0009931 calcium-dependent protein serine/threonine kinase activity 2/573 21/18639 0.0952380952380952 3.09798055347794 0.135122736384774 0.408043906904515 GO:0051010 microtubule plus-end binding 2/573 21/18639 0.0952380952380952 3.09798055347794 0.135122736384774 0.408043906904515 GO:0051428 peptide hormone receptor binding 2/573 21/18639 0.0952380952380952 3.09798055347794 0.135122736384774 0.408043906904515 GO:0061891 calcium ion sensor activity 2/573 21/18639 0.0952380952380952 3.09798055347794 0.135122736384774 0.408043906904515 GO:0030021 extracellular matrix structural constituent conferring compression resistance 2/573 22/18639 0.0909090909090909 2.95716325559258 0.145752607678016 0.432998818264236 GO:0050321 tau-protein kinase activity 2/573 22/18639 0.0909090909090909 2.95716325559258 0.145752607678016 0.432998818264236 GO:0140035 ubiquitin-like protein reader activity 2/573 22/18639 0.0909090909090909 2.95716325559258 0.145752607678016 0.432998818264236 GO:0140517 protein-RNA adaptor activity 2/573 22/18639 0.0909090909090909 2.95716325559258 0.145752607678016 0.432998818264236 GO:0140784 metal ion sensor activity 2/573 22/18639 0.0909090909090909 2.95716325559258 0.145752607678016 0.432998818264236 GO:0022843 voltage-gated monoatomic cation channel activity 7/573 143/18639 0.048951048951049 1.59231867608831 0.151973119848639 0.450017490813932 GO:0019903 protein phosphatase binding 7/573 144/18639 0.0486111111111111 1.58126090750436 0.155817965369869 0.459914317140096 GO:0005548 phospholipid transporter activity 4/573 68/18639 0.0588235294117647 1.91345857714814 0.156521599200545 0.46050566967363 GO:0051213 dioxygenase activity 5/573 93/18639 0.0537634408602151 1.74885998986658 0.15828243142289 0.464193669076746 GO:0015149 hexose transmembrane transporter activity 2/573 24/18639 0.0833333333333333 2.71073298429319 0.167486128073668 0.483437877562797 GO:0030215 semaphorin receptor binding 2/573 24/18639 0.0833333333333333 2.71073298429319 0.167486128073668 0.483437877562797 GO:0048027 mRNA 5'-UTR binding 2/573 24/18639 0.0833333333333333 2.71073298429319 0.167486128073668 0.483437877562797 GO:0055056 D-glucose transmembrane transporter activity 2/573 24/18639 0.0833333333333333 2.71073298429319 0.167486128073668 0.483437877562797 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 2/573 24/18639 0.0833333333333333 2.71073298429319 0.167486128073668 0.483437877562797 GO:0005504 fatty acid binding 3/573 47/18639 0.0638297872340425 2.07630611562883 0.175088467404635 0.503792288286921 GO:0008509 monoatomic anion transmembrane transporter activity 7/573 149/18639 0.0469798657718121 1.52819846094381 0.175694286278661 0.503950695752273 GO:0003714 transcription corepressor activity 9/573 204/18639 0.0441176470588235 1.4350939328611 0.177864681575878 0.505801293764079 GO:0004709 MAP kinase kinase kinase activity 2/573 25/18639 0.08 2.60230366492147 0.178550620640216 0.505801293764079 GO:0015296 monoatomic anion:monoatomic cation symporter activity 2/573 25/18639 0.08 2.60230366492147 0.178550620640216 0.505801293764079 GO:0017025 TBP-class protein binding 2/573 25/18639 0.08 2.60230366492147 0.178550620640216 0.505801293764079 GO:0019842 vitamin binding 7/573 150/18639 0.0466666666666667 1.51801047120419 0.179795018540087 0.507754450506727 GO:0005249 voltage-gated potassium channel activity 5/573 98/18639 0.0510204081632653 1.65963243936318 0.183786662613443 0.51743014243477 GO:0043539 protein serine/threonine kinase activator activity 4/573 73/18639 0.0547945205479452 1.78239977049415 0.186695790209329 0.524008122826797 GO:0008198 ferrous iron binding 2/573 26/18639 0.0769230769230769 2.50221506242449 0.189722578987999 0.526048969012179 GO:0015145 monosaccharide transmembrane transporter activity 2/573 26/18639 0.0769230769230769 2.50221506242449 0.189722578987999 0.526048969012179 GO:0019865 immunoglobulin binding 2/573 26/18639 0.0769230769230769 2.50221506242449 0.189722578987999 0.526048969012179 GO:0034237 protein kinase A regulatory subunit binding 2/573 26/18639 0.0769230769230769 2.50221506242449 0.189722578987999 0.526048969012179 GO:0031491 nucleosome binding 4/573 74/18639 0.0540540540540541 1.7583132871091 0.19294433556438 0.533365761454404 GO:0043130 ubiquitin binding 5/573 100/18639 0.05 1.62643979057592 0.194387791460051 0.535184130088731 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 8/573 181/18639 0.0441988950276243 1.43773683144832 0.194771929310981 0.535184130088731 GO:0048020 CCR chemokine receptor binding 3/573 50/18639 0.06 1.9517277486911 0.198475424856644 0.543727586059368 GO:0005385 zinc ion transmembrane transporter activity 2/573 27/18639 0.0740740740740741 2.40954043048284 0.200984978999343 0.547325166024996 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity 2/573 27/18639 0.0740740740740741 2.40954043048284 0.200984978999343 0.547325166024996 GO:0015631 tubulin binding 15/573 385/18639 0.038961038961039 1.26735568096825 0.208281037737689 0.564751135389668 GO:0016298 lipase activity 6/573 130/18639 0.0461538461538462 1.50132903745469 0.211267015575057 0.564751135389668 GO:0005242 inward rectifier potassium channel activity 2/573 28/18639 0.0714285714285714 2.32348541510845 0.212321738332291 0.564751135389668 GO:0051119 sugar transmembrane transporter activity 2/573 28/18639 0.0714285714285714 2.32348541510845 0.212321738332291 0.564751135389668 GO:0051393 alpha-actinin binding 2/573 28/18639 0.0714285714285714 2.32348541510845 0.212321738332291 0.564751135389668 GO:0051959 dynein light intermediate chain binding 2/573 28/18639 0.0714285714285714 2.32348541510845 0.212321738332291 0.564751135389668 GO:0097718 disordered domain specific binding 2/573 28/18639 0.0714285714285714 2.32348541510845 0.212321738332291 0.564751135389668 GO:0141052 histone H3 demethylase activity 2/573 28/18639 0.0714285714285714 2.32348541510845 0.212321738332291 0.564751135389668 GO:0005080 protein kinase C binding 3/573 52/18639 0.0576923076923077 1.87666129681836 0.214459921882465 0.568785010210017 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 2/573 29/18639 0.0689655172413793 2.24336522838057 0.223717674774217 0.586537743319222 GO:0043236 laminin binding 2/573 29/18639 0.0689655172413793 2.24336522838057 0.223717674774217 0.586537743319222 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 2/573 29/18639 0.0689655172413793 2.24336522838057 0.223717674774217 0.586537743319222 GO:0097472 cyclin-dependent protein kinase activity 2/573 29/18639 0.0689655172413793 2.24336522838057 0.223717674774217 0.586537743319222 GO:0046873 metal ion transmembrane transporter activity 17/573 450/18639 0.0377777777777778 1.22886561954625 0.224701909414963 0.586785046219044 GO:0033293 monocarboxylic acid binding 4/573 79/18639 0.0506329113924051 1.64702763602624 0.22509459150042 0.586785046219044 GO:0000149 SNARE binding 5/573 106/18639 0.0471698113207547 1.53437716092068 0.227381826602417 0.591063554946625 GO:0140463 chromatin-protein adaptor activity 3/573 54/18639 0.0555555555555556 1.80715532286213 0.230704828295763 0.598002600256723 GO:0032452 histone demethylase activity 2/573 30/18639 0.0666666666666667 2.16858638743456 0.235158466258829 0.602717077386074 GO:0033612 receptor serine/threonine kinase binding 2/573 30/18639 0.0666666666666667 2.16858638743456 0.235158466258829 0.602717077386074 GO:0035925 mRNA 3'-UTR AU-rich region binding 2/573 30/18639 0.0666666666666667 2.16858638743456 0.235158466258829 0.602717077386074 GO:0051721 protein phosphatase 2A binding 2/573 30/18639 0.0666666666666667 2.16858638743456 0.235158466258829 0.602717077386074 GO:0015101 organic cation transmembrane transporter activity 4/573 81/18639 0.0493827160493827 1.60636028698856 0.238323480561291 0.608461159067576 GO:0005496 steroid binding 5/573 108/18639 0.0462962962962963 1.50596276905177 0.238729569513945 0.608461159067576 GO:0004620 phospholipase activity 5/573 109/18639 0.0458715596330275 1.49214659685864 0.244460972407298 0.621338304868548 GO:0008327 methyl-CpG binding 2/573 31/18639 0.0645161290322581 2.09863198783989 0.246630612483927 0.623389531554677 GO:0140457 protein demethylase activity 2/573 31/18639 0.0645161290322581 2.09863198783989 0.246630612483927 0.623389531554677 GO:0008236 serine-type peptidase activity 8/573 194/18639 0.0412371134020619 1.3413936417121 0.248055595867189 0.624521505021719 GO:0140767 enzyme-substrate adaptor activity 6/573 139/18639 0.0431654676258993 1.40412068251158 0.256498682188948 0.624521505021719 GO:0015106 bicarbonate transmembrane transporter activity 2/573 32/18639 0.0625 2.0330497382199 0.258121398069562 0.624521505021719 GO:0043425 bHLH transcription factor binding 2/573 32/18639 0.0625 2.0330497382199 0.258121398069562 0.624521505021719 GO:0051117 ATPase binding 4/573 84/18639 0.0476190476190476 1.54899027673897 0.258489331486759 0.624521505021719 GO:0005200 structural constituent of cytoskeleton 5/573 112/18639 0.0446428571428571 1.45217838444278 0.261863780350869 0.624521505021719 GO:0017171 serine hydrolase activity 8/573 198/18639 0.0404040404040404 1.31429478026337 0.265338977255893 0.624521505021719 GO:0004175 endopeptidase activity 15/573 405/18639 0.037037037037037 1.20477021524142 0.266103953386769 0.624521505021719 GO:0004955 prostaglandin receptor activity 1/573 10/18639 0.1 3.25287958115183 0.268253408089413 0.624521505021719 GO:0005131 growth hormone receptor binding 1/573 10/18639 0.1 3.25287958115183 0.268253408089413 0.624521505021719 GO:0005381 iron ion transmembrane transporter activity 1/573 10/18639 0.1 3.25287958115183 0.268253408089413 0.624521505021719 GO:0005528 FK506 binding 1/573 10/18639 0.1 3.25287958115183 0.268253408089413 0.624521505021719 GO:0008140 cAMP response element binding protein binding 1/573 10/18639 0.1 3.25287958115183 0.268253408089413 0.624521505021719 GO:0008239 dipeptidyl-peptidase activity 1/573 10/18639 0.1 3.25287958115183 0.268253408089413 0.624521505021719 GO:0015187 glycine transmembrane transporter activity 1/573 10/18639 0.1 3.25287958115183 0.268253408089413 0.624521505021719 GO:0015643 toxic substance binding 1/573 10/18639 0.1 3.25287958115183 0.268253408089413 0.624521505021719 GO:0015924 mannosyl-oligosaccharide mannosidase activity 1/573 10/18639 0.1 3.25287958115183 0.268253408089413 0.624521505021719 GO:0016303 1-phosphatidylinositol-3-kinase activity 1/573 10/18639 0.1 3.25287958115183 0.268253408089413 0.624521505021719 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines 1/573 10/18639 0.1 3.25287958115183 0.268253408089413 0.624521505021719 GO:0031434 mitogen-activated protein kinase kinase binding 1/573 10/18639 0.1 3.25287958115183 0.268253408089413 0.624521505021719 GO:0034596 phosphatidylinositol phosphate 4-phosphatase activity 1/573 10/18639 0.1 3.25287958115183 0.268253408089413 0.624521505021719 GO:0035256 G protein-coupled glutamate receptor binding 1/573 10/18639 0.1 3.25287958115183 0.268253408089413 0.624521505021719 GO:0035374 chondroitin sulfate binding 1/573 10/18639 0.1 3.25287958115183 0.268253408089413 0.624521505021719 GO:0042975 peroxisome proliferator activated receptor binding 1/573 10/18639 0.1 3.25287958115183 0.268253408089413 0.624521505021719 GO:0043121 neurotrophin binding 1/573 10/18639 0.1 3.25287958115183 0.268253408089413 0.624521505021719 GO:0050815 phosphoserine residue binding 1/573 10/18639 0.1 3.25287958115183 0.268253408089413 0.624521505021719 GO:0051864 histone H3K36 demethylase activity 1/573 10/18639 0.1 3.25287958115183 0.268253408089413 0.624521505021719 GO:0140999 histone H3K4 trimethyltransferase activity 1/573 10/18639 0.1 3.25287958115183 0.268253408089413 0.624521505021719 GO:0019239 deaminase activity 2/573 33/18639 0.0606060606060606 1.97144217039505 0.269618857198402 0.624521505021719 GO:0019956 chemokine binding 2/573 33/18639 0.0606060606060606 1.97144217039505 0.269618857198402 0.624521505021719 GO:0016209 antioxidant activity 4/573 86/18639 0.0465116279069767 1.51296724704736 0.272114984216204 0.624521505021719 GO:0050660 flavin adenine dinucleotide binding 4/573 86/18639 0.0465116279069767 1.51296724704736 0.272114984216204 0.624521505021719 GO:0004879 nuclear receptor activity 3/573 59/18639 0.0508474576271186 1.65400656668737 0.272167310473285 0.624521505021719 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 13/573 349/18639 0.0372492836676218 1.21167434254939 0.278573558129985 0.624521505021719 GO:0098531 ligand-modulated transcription factor activity 3/573 60/18639 0.05 1.62643979057592 0.280563713628746 0.624521505021719 GO:0008376 acetylgalactosaminyltransferase activity 2/573 34/18639 0.0588235294117647 1.91345857714814 0.281111739682254 0.624521505021719 GO:0015035 protein-disulfide reductase activity 2/573 34/18639 0.0588235294117647 1.91345857714814 0.281111739682254 0.624521505021719 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 2/573 34/18639 0.0588235294117647 1.91345857714814 0.281111739682254 0.624521505021719 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 2/573 34/18639 0.0588235294117647 1.91345857714814 0.281111739682254 0.624521505021719 GO:0090482 vitamin transmembrane transporter activity 2/573 34/18639 0.0588235294117647 1.91345857714814 0.281111739682254 0.624521505021719 GO:0005244 voltage-gated monoatomic ion channel activity 7/573 173/18639 0.0404624277456647 1.31619405017704 0.283505785121329 0.624521505021719 GO:0015026 coreceptor activity 3/573 61/18639 0.0491803278688525 1.59977684318943 0.288983165202363 0.624521505021719 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding 1/573 11/18639 0.0909090909090909 2.95716325559258 0.290760831846178 0.624521505021719 GO:0004143 ATP-dependent diacylglycerol kinase activity 1/573 11/18639 0.0909090909090909 2.95716325559258 0.290760831846178 0.624521505021719 GO:0004954 prostanoid receptor activity 1/573 11/18639 0.0909090909090909 2.95716325559258 0.290760831846178 0.624521505021719 GO:0005114 type II transforming growth factor beta receptor binding 1/573 11/18639 0.0909090909090909 2.95716325559258 0.290760831846178 0.624521505021719 GO:0005225 volume-sensitive anion channel activity 1/573 11/18639 0.0909090909090909 2.95716325559258 0.290760831846178 0.624521505021719 GO:0008046 axon guidance receptor activity 1/573 11/18639 0.0909090909090909 2.95716325559258 0.290760831846178 0.624521505021719 GO:0008199 ferric iron binding 1/573 11/18639 0.0909090909090909 2.95716325559258 0.290760831846178 0.624521505021719 GO:0008526 phosphatidylinositol transfer activity 1/573 11/18639 0.0909090909090909 2.95716325559258 0.290760831846178 0.624521505021719 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity 1/573 11/18639 0.0909090909090909 2.95716325559258 0.290760831846178 0.624521505021719 GO:0015173 aromatic amino acid transmembrane transporter activity 1/573 11/18639 0.0909090909090909 2.95716325559258 0.290760831846178 0.624521505021719 GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor 1/573 11/18639 0.0909090909090909 2.95716325559258 0.290760831846178 0.624521505021719 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 1/573 11/18639 0.0909090909090909 2.95716325559258 0.290760831846178 0.624521505021719 GO:0019206 nucleoside kinase activity 1/573 11/18639 0.0909090909090909 2.95716325559258 0.290760831846178 0.624521505021719 GO:0019215 intermediate filament binding 1/573 11/18639 0.0909090909090909 2.95716325559258 0.290760831846178 0.624521505021719 GO:0034594 phosphatidylinositol trisphosphate phosphatase activity 1/573 11/18639 0.0909090909090909 2.95716325559258 0.290760831846178 0.624521505021719 GO:0034713 type I transforming growth factor beta receptor binding 1/573 11/18639 0.0909090909090909 2.95716325559258 0.290760831846178 0.624521505021719 GO:0042608 T cell receptor binding 1/573 11/18639 0.0909090909090909 2.95716325559258 0.290760831846178 0.624521505021719 GO:0043522 leucine zipper domain binding 1/573 11/18639 0.0909090909090909 2.95716325559258 0.290760831846178 0.624521505021719 GO:0045294 alpha-catenin binding 1/573 11/18639 0.0909090909090909 2.95716325559258 0.290760831846178 0.624521505021719 GO:0048407 platelet-derived growth factor binding 1/573 11/18639 0.0909090909090909 2.95716325559258 0.290760831846178 0.624521505021719 GO:0050786 RAGE receptor binding 1/573 11/18639 0.0909090909090909 2.95716325559258 0.290760831846178 0.624521505021719 GO:0140031 phosphorylation-dependent protein binding 1/573 11/18639 0.0909090909090909 2.95716325559258 0.290760831846178 0.624521505021719 GO:0043015 gamma-tubulin binding 2/573 35/18639 0.0571428571428571 1.85878833208676 0.292589478400696 0.625325059578175 GO:0140566 histone reader activity 2/573 35/18639 0.0571428571428571 1.85878833208676 0.292589478400696 0.625325059578175 GO:0022832 voltage-gated channel activity 7/573 175/18639 0.04 1.30115183246073 0.2931851918678 0.625325059578175 GO:0004869 cysteine-type endopeptidase inhibitor activity 2/573 36/18639 0.0555555555555556 1.80715532286213 0.30404215805978 0.625838240658071 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 2/573 36/18639 0.0555555555555556 1.80715532286213 0.30404215805978 0.625838240658071 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 2/573 36/18639 0.0555555555555556 1.80715532286213 0.30404215805978 0.625838240658071 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 2/573 36/18639 0.0555555555555556 1.80715532286213 0.30404215805978 0.625838240658071 GO:0032182 ubiquitin-like protein binding 5/573 120/18639 0.0416666666666667 1.3553664921466 0.309487732145556 0.625838240658071 GO:0000995 RNA polymerase III general transcription initiation factor activity 1/573 12/18639 0.0833333333333333 2.71073298429319 0.312577132219387 0.625838240658071 GO:0004000 adenosine deaminase activity 1/573 12/18639 0.0833333333333333 2.71073298429319 0.312577132219387 0.625838240658071 GO:0005095 GTPase inhibitor activity 1/573 12/18639 0.0833333333333333 2.71073298429319 0.312577132219387 0.625838240658071 GO:0005165 neurotrophin receptor binding 1/573 12/18639 0.0833333333333333 2.71073298429319 0.312577132219387 0.625838240658071 GO:0008504 monoamine transmembrane transporter activity 1/573 12/18639 0.0833333333333333 2.71073298429319 0.312577132219387 0.625838240658071 GO:0015132 prostaglandin transmembrane transporter activity 1/573 12/18639 0.0833333333333333 2.71073298429319 0.312577132219387 0.625838240658071 GO:0015269 calcium-activated potassium channel activity 1/573 12/18639 0.0833333333333333 2.71073298429319 0.312577132219387 0.625838240658071 GO:0016208 AMP binding 1/573 12/18639 0.0833333333333333 2.71073298429319 0.312577132219387 0.625838240658071 GO:0016840 carbon-nitrogen lyase activity 1/573 12/18639 0.0833333333333333 2.71073298429319 0.312577132219387 0.625838240658071 GO:0031543 peptidyl-proline dioxygenase activity 1/573 12/18639 0.0833333333333333 2.71073298429319 0.312577132219387 0.625838240658071 GO:0035014 phosphatidylinositol 3-kinase regulator activity 1/573 12/18639 0.0833333333333333 2.71073298429319 0.312577132219387 0.625838240658071 GO:0035197 siRNA binding 1/573 12/18639 0.0833333333333333 2.71073298429319 0.312577132219387 0.625838240658071 GO:0035251 UDP-glucosyltransferase activity 1/573 12/18639 0.0833333333333333 2.71073298429319 0.312577132219387 0.625838240658071 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity 1/573 12/18639 0.0833333333333333 2.71073298429319 0.312577132219387 0.625838240658071 GO:0070008 serine-type exopeptidase activity 1/573 12/18639 0.0833333333333333 2.71073298429319 0.312577132219387 0.625838240658071 GO:0070410 co-SMAD binding 1/573 12/18639 0.0833333333333333 2.71073298429319 0.312577132219387 0.625838240658071 GO:0070679 inositol 1,4,5 trisphosphate binding 1/573 12/18639 0.0833333333333333 2.71073298429319 0.312577132219387 0.625838240658071 GO:0097677 STAT family protein binding 1/573 12/18639 0.0833333333333333 2.71073298429319 0.312577132219387 0.625838240658071 GO:0140807 NAD+-protein-glutamate ADP-ribosyltransferase activity 1/573 12/18639 0.0833333333333333 2.71073298429319 0.312577132219387 0.625838240658071 GO:0140822 NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity 1/573 12/18639 0.0833333333333333 2.71073298429319 0.312577132219387 0.625838240658071 GO:0140844 NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity 1/573 12/18639 0.0833333333333333 2.71073298429319 0.312577132219387 0.625838240658071 GO:0140867 NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity 1/573 12/18639 0.0833333333333333 2.71073298429319 0.312577132219387 0.625838240658071 GO:1990459 transferrin receptor binding 1/573 12/18639 0.0833333333333333 2.71073298429319 0.312577132219387 0.625838240658071 GO:0052689 carboxylic ester hydrolase activity 4/573 92/18639 0.0434782608695652 1.41429547006601 0.313621246471145 0.626130897997528 GO:0008514 organic anion transmembrane transporter activity 10/573 269/18639 0.0371747211895911 1.20924891492633 0.315140003964079 0.626130897997528 GO:0019213 deacetylase activity 2/573 37/18639 0.0540540540540541 1.7583132871091 0.315460485220612 0.626130897997528 GO:0042805 actinin binding 2/573 37/18639 0.0540540540540541 1.7583132871091 0.315460485220612 0.626130897997528 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 5/573 122/18639 0.040983606557377 1.33314736932452 0.321594324526177 0.636218333960827 GO:0038024 cargo receptor activity 3/573 65/18639 0.0461538461538462 1.50132903745469 0.322798927168691 0.636218333960827 GO:0160215 deacylase activity 3/573 65/18639 0.0461538461538462 1.50132903745469 0.322798927168691 0.636218333960827 GO:0016410 N-acyltransferase activity 4/573 94/18639 0.0425531914893617 1.38420407708589 0.327595667165622 0.636218333960827 GO:0005338 nucleotide-sugar transmembrane transporter activity 1/573 13/18639 0.0769230769230769 2.50221506242449 0.333723495199915 0.636218333960827 GO:0008253 5'-nucleotidase activity 1/573 13/18639 0.0769230769230769 2.50221506242449 0.333723495199915 0.636218333960827 GO:0008417 fucosyltransferase activity 1/573 13/18639 0.0769230769230769 2.50221506242449 0.333723495199915 0.636218333960827 GO:0019855 calcium channel inhibitor activity 1/573 13/18639 0.0769230769230769 2.50221506242449 0.333723495199915 0.636218333960827 GO:0030955 potassium ion binding 1/573 13/18639 0.0769230769230769 2.50221506242449 0.333723495199915 0.636218333960827 GO:0035325 Toll-like receptor binding 1/573 13/18639 0.0769230769230769 2.50221506242449 0.333723495199915 0.636218333960827 GO:0051011 microtubule minus-end binding 1/573 13/18639 0.0769230769230769 2.50221506242449 0.333723495199915 0.636218333960827 GO:0061459 L-arginine transmembrane transporter activity 1/573 13/18639 0.0769230769230769 2.50221506242449 0.333723495199915 0.636218333960827 GO:0070123 transforming growth factor beta receptor activity, type III 1/573 13/18639 0.0769230769230769 2.50221506242449 0.333723495199915 0.636218333960827 GO:0071714 icosanoid transmembrane transporter activity 1/573 13/18639 0.0769230769230769 2.50221506242449 0.333723495199915 0.636218333960827 GO:0071837 HMG box domain binding 1/573 13/18639 0.0769230769230769 2.50221506242449 0.333723495199915 0.636218333960827 GO:0097157 pre-mRNA intronic binding 1/573 13/18639 0.0769230769230769 2.50221506242449 0.333723495199915 0.636218333960827 GO:0140333 glycerophospholipid flippase activity 1/573 13/18639 0.0769230769230769 2.50221506242449 0.333723495199915 0.636218333960827 GO:0140806 NAD+-protein-aspartate ADP-ribosyltransferase activity 1/573 13/18639 0.0769230769230769 2.50221506242449 0.333723495199915 0.636218333960827 GO:0005267 potassium channel activity 5/573 124/18639 0.0403225806451613 1.31164499239993 0.333753880110598 0.636218333960827 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 2/573 39/18639 0.0512820512820513 1.66814337494966 0.338159846243007 0.643277046387426 GO:0140375 immune receptor activity 6/573 156/18639 0.0384615384615385 1.25110753121224 0.347498268316136 0.644357295168355 GO:0003777 microtubule motor activity 3/573 68/18639 0.0441176470588235 1.4350939328611 0.348184059768414 0.644357295168355 GO:1990841 promoter-specific chromatin binding 3/573 68/18639 0.0441176470588235 1.4350939328611 0.348184059768414 0.644357295168355 GO:0015036 disulfide oxidoreductase activity 2/573 40/18639 0.05 1.62643979057592 0.349425149583273 0.644357295168355 GO:0015144 carbohydrate transmembrane transporter activity 2/573 40/18639 0.05 1.62643979057592 0.349425149583273 0.644357295168355 GO:0032451 demethylase activity 2/573 40/18639 0.05 1.62643979057592 0.349425149583273 0.644357295168355 GO:0005313 L-glutamate transmembrane transporter activity 1/573 14/18639 0.0714285714285714 2.32348541510845 0.354220458436811 0.644357295168355 GO:0005545 1-phosphatidylinositol binding 1/573 14/18639 0.0714285714285714 2.32348541510845 0.354220458436811 0.644357295168355 GO:0008195 phosphatidate phosphatase activity 1/573 14/18639 0.0714285714285714 2.32348541510845 0.354220458436811 0.644357295168355 GO:0008331 high voltage-gated calcium channel activity 1/573 14/18639 0.0714285714285714 2.32348541510845 0.354220458436811 0.644357295168355 GO:0008494 translation activator activity 1/573 14/18639 0.0714285714285714 2.32348541510845 0.354220458436811 0.644357295168355 GO:0015926 glucosidase activity 1/573 14/18639 0.0714285714285714 2.32348541510845 0.354220458436811 0.644357295168355 GO:0016530 metallochaperone activity 1/573 14/18639 0.0714285714285714 2.32348541510845 0.354220458436811 0.644357295168355 GO:0019992 diacylglycerol binding 1/573 14/18639 0.0714285714285714 2.32348541510845 0.354220458436811 0.644357295168355 GO:0032036 myosin heavy chain binding 1/573 14/18639 0.0714285714285714 2.32348541510845 0.354220458436811 0.644357295168355 GO:0032454 histone H3K9 demethylase activity 1/573 14/18639 0.0714285714285714 2.32348541510845 0.354220458436811 0.644357295168355 GO:0042043 neurexin family protein binding 1/573 14/18639 0.0714285714285714 2.32348541510845 0.354220458436811 0.644357295168355 GO:0043176 amine binding 1/573 14/18639 0.0714285714285714 2.32348541510845 0.354220458436811 0.644357295168355 GO:0052816 long-chain fatty acyl-CoA hydrolase activity 1/573 14/18639 0.0714285714285714 2.32348541510845 0.354220458436811 0.644357295168355 GO:0070742 C2H2 zinc finger domain binding 1/573 14/18639 0.0714285714285714 2.32348541510845 0.354220458436811 0.644357295168355 GO:1901474 azole transmembrane transporter activity 1/573 14/18639 0.0714285714285714 2.32348541510845 0.354220458436811 0.644357295168355 GO:1901612 cardiolipin binding 1/573 14/18639 0.0714285714285714 2.32348541510845 0.354220458436811 0.644357295168355 GO:0017080 sodium channel regulator activity 2/573 41/18639 0.0487804878048781 1.58677052739114 0.360624587579985 0.654475061004962 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 5/573 130/18639 0.0384615384615385 1.25110753121224 0.370419896908121 0.654475061004962 GO:0008307 structural constituent of muscle 2/573 42/18639 0.0476190476190476 1.54899027673897 0.371751567657729 0.654475061004962 GO:0016859 cis-trans isomerase activity 2/573 42/18639 0.0476190476190476 1.54899027673897 0.371751567657729 0.654475061004962 GO:0031492 nucleosomal DNA binding 2/573 42/18639 0.0476190476190476 1.54899027673897 0.371751567657729 0.654475061004962 GO:0042056 chemoattractant activity 2/573 42/18639 0.0476190476190476 1.54899027673897 0.371751567657729 0.654475061004962 GO:0140299 molecular sensor activity 3/573 71/18639 0.0422535211267606 1.37445616105007 0.373469496820413 0.654475061004962 GO:0004559 alpha-mannosidase activity 1/573 15/18639 0.0666666666666667 2.16858638743456 0.374087931044366 0.654475061004962 GO:0004953 icosanoid receptor activity 1/573 15/18639 0.0666666666666667 2.16858638743456 0.374087931044366 0.654475061004962 GO:0005041 low-density lipoprotein particle receptor activity 1/573 15/18639 0.0666666666666667 2.16858638743456 0.374087931044366 0.654475061004962 GO:0005402 carbohydrate:monoatomic cation symporter activity 1/573 15/18639 0.0666666666666667 2.16858638743456 0.374087931044366 0.654475061004962 GO:0008242 omega peptidase activity 1/573 15/18639 0.0666666666666667 2.16858638743456 0.374087931044366 0.654475061004962 GO:0008252 nucleotidase activity 1/573 15/18639 0.0666666666666667 2.16858638743456 0.374087931044366 0.654475061004962 GO:0015929 hexosaminidase activity 1/573 15/18639 0.0666666666666667 2.16858638743456 0.374087931044366 0.654475061004962 GO:0017081 chloride channel regulator activity 1/573 15/18639 0.0666666666666667 2.16858638743456 0.374087931044366 0.654475061004962 GO:0030553 cGMP binding 1/573 15/18639 0.0666666666666667 2.16858638743456 0.374087931044366 0.654475061004962 GO:0034483 heparan sulfate sulfotransferase activity 1/573 15/18639 0.0666666666666667 2.16858638743456 0.374087931044366 0.654475061004962 GO:0042809 nuclear vitamin D receptor binding 1/573 15/18639 0.0666666666666667 2.16858638743456 0.374087931044366 0.654475061004962 GO:0051371 muscle alpha-actinin binding 1/573 15/18639 0.0666666666666667 2.16858638743456 0.374087931044366 0.654475061004962 GO:0061578 K63-linked deubiquitinase activity 1/573 15/18639 0.0666666666666667 2.16858638743456 0.374087931044366 0.654475061004962 GO:0042379 chemokine receptor binding 3/573 72/18639 0.0416666666666667 1.3553664921466 0.381858840301409 0.662305412011378 GO:0004712 protein serine/threonine/tyrosine kinase activity 2/573 43/18639 0.0465116279069767 1.51296724704736 0.382799963348378 0.662305412011378 GO:0005245 voltage-gated calcium channel activity 2/573 43/18639 0.0465116279069767 1.51296724704736 0.382799963348378 0.662305412011378 GO:0048156 tau protein binding 2/573 43/18639 0.0465116279069767 1.51296724704736 0.382799963348378 0.662305412011378 GO:0008238 exopeptidase activity 4/573 102/18639 0.0392156862745098 1.27563905143209 0.3836608580308 0.662305412011378 GO:0015171 amino acid transmembrane transporter activity 4/573 102/18639 0.0392156862745098 1.27563905143209 0.3836608580308 0.662305412011378 GO:0015291 secondary active transmembrane transporter activity 10/573 287/18639 0.0348432055749129 1.1334075195651 0.388682327919216 0.662305412011378 GO:0005253 monoatomic anion channel activity 4/573 103/18639 0.0388349514563107 1.26325420627256 0.390650196200753 0.662305412011378 GO:0015081 sodium ion transmembrane transporter activity 6/573 164/18639 0.0365853658536585 1.19007789554335 0.391462089731977 0.662305412011378 GO:0004708 MAP kinase kinase activity 1/573 16/18639 0.0625 2.0330497382199 0.393345212805083 0.662305412011378 GO:0015378 sodium:chloride symporter activity 1/573 16/18639 0.0625 2.0330497382199 0.393345212805083 0.662305412011378 GO:0015923 mannosidase activity 1/573 16/18639 0.0625 2.0330497382199 0.393345212805083 0.662305412011378 GO:0016722 oxidoreductase activity, acting on metal ions 1/573 16/18639 0.0625 2.0330497382199 0.393345212805083 0.662305412011378 GO:0019841 retinol binding 1/573 16/18639 0.0625 2.0330497382199 0.393345212805083 0.662305412011378 GO:0022841 potassium ion leak channel activity 1/573 16/18639 0.0625 2.0330497382199 0.393345212805083 0.662305412011378 GO:0030275 LRR domain binding 1/573 16/18639 0.0625 2.0330497382199 0.393345212805083 0.662305412011378 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 1/573 16/18639 0.0625 2.0330497382199 0.393345212805083 0.662305412011378 GO:0106018 phosphatidylinositol-3,5-bisphosphate phosphatase activity 1/573 16/18639 0.0625 2.0330497382199 0.393345212805083 0.662305412011378 GO:0140327 flippase activity 1/573 16/18639 0.0625 2.0330497382199 0.393345212805083 0.662305412011378 GO:0140328 floppase activity 1/573 16/18639 0.0625 2.0330497382199 0.393345212805083 0.662305412011378 GO:0019205 nucleobase-containing compound kinase activity 2/573 44/18639 0.0454545454545455 1.47858162779629 0.393764091949934 0.662305412011378 GO:0008009 chemokine activity 2/573 45/18639 0.0444444444444444 1.4457242582897 0.404638693114583 0.674400852772948 GO:0046915 transition metal ion transmembrane transporter activity 2/573 45/18639 0.0444444444444444 1.4457242582897 0.404638693114583 0.674400852772948 GO:0140303 intramembrane lipid transporter activity 2/573 45/18639 0.0444444444444444 1.4457242582897 0.404638693114583 0.674400852772948 GO:0003725 double-stranded RNA binding 3/573 75/18639 0.04 1.30115183246073 0.406862912519802 0.674400852772948 GO:0004029 aldehyde dehydrogenase (NAD+) activity 1/573 17/18639 0.0588235294117647 1.91345857714814 0.41201101278697 0.674400852772948 GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity 1/573 17/18639 0.0588235294117647 1.91345857714814 0.41201101278697 0.674400852772948 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 1/573 17/18639 0.0588235294117647 1.91345857714814 0.41201101278697 0.674400852772948 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 1/573 17/18639 0.0588235294117647 1.91345857714814 0.41201101278697 0.674400852772948 GO:0005092 GDP-dissociation inhibitor activity 1/573 17/18639 0.0588235294117647 1.91345857714814 0.41201101278697 0.674400852772948 GO:0008429 phosphatidylethanolamine binding 1/573 17/18639 0.0588235294117647 1.91345857714814 0.41201101278697 0.674400852772948 GO:0015347 sodium-independent organic anion transmembrane transporter activity 1/573 17/18639 0.0588235294117647 1.91345857714814 0.41201101278697 0.674400852772948 GO:0016018 cyclosporin A binding 1/573 17/18639 0.0588235294117647 1.91345857714814 0.41201101278697 0.674400852772948 GO:0019198 transmembrane receptor protein phosphatase activity 1/573 17/18639 0.0588235294117647 1.91345857714814 0.41201101278697 0.674400852772948 GO:0038191 neuropilin binding 1/573 17/18639 0.0588235294117647 1.91345857714814 0.41201101278697 0.674400852772948 GO:1990226 histone methyltransferase binding 1/573 17/18639 0.0588235294117647 1.91345857714814 0.41201101278697 0.674400852772948 GO:0004180 carboxypeptidase activity 2/573 46/18639 0.0434782608695652 1.41429547006601 0.41541890833011 0.676349290252759 GO:0030276 clathrin binding 2/573 46/18639 0.0434782608695652 1.41429547006601 0.41541890833011 0.676349290252759 GO:0030291 protein serine/threonine kinase inhibitor activity 2/573 46/18639 0.0434782608695652 1.41429547006601 0.41541890833011 0.676349290252759 GO:0004843 cysteine-type deubiquitinase activity 4/573 108/18639 0.037037037037037 1.20477021524142 0.425387964973907 0.678525297697542 GO:0061749 forked DNA-dependent helicase activity 2/573 47/18639 0.0425531914893617 1.38420407708589 0.426100261260131 0.678525297697542 GO:0140938 histone H3 methyltransferase activity 2/573 47/18639 0.0425531914893617 1.38420407708589 0.426100261260131 0.678525297697542 GO:1990518 single-stranded 3'-5' DNA helicase activity 2/573 47/18639 0.0425531914893617 1.38420407708589 0.426100261260131 0.678525297697542 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity 1/573 18/18639 0.0555555555555556 1.80715532286213 0.430103467392977 0.678525297697542 GO:0004706 JUN kinase kinase kinase activity 1/573 18/18639 0.0555555555555556 1.80715532286213 0.430103467392977 0.678525297697542 GO:0008525 phosphatidylcholine transporter activity 1/573 18/18639 0.0555555555555556 1.80715532286213 0.430103467392977 0.678525297697542 GO:0015373 monoatomic anion:sodium symporter activity 1/573 18/18639 0.0555555555555556 1.80715532286213 0.430103467392977 0.678525297697542 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 1/573 18/18639 0.0555555555555556 1.80715532286213 0.430103467392977 0.678525297697542 GO:0017075 syntaxin-1 binding 1/573 18/18639 0.0555555555555556 1.80715532286213 0.430103467392977 0.678525297697542 GO:0017128 phospholipid scramblase activity 1/573 18/18639 0.0555555555555556 1.80715532286213 0.430103467392977 0.678525297697542 GO:0030228 lipoprotein particle receptor activity 1/573 18/18639 0.0555555555555556 1.80715532286213 0.430103467392977 0.678525297697542 GO:0031690 adrenergic receptor binding 1/573 18/18639 0.0555555555555556 1.80715532286213 0.430103467392977 0.678525297697542 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 1/573 18/18639 0.0555555555555556 1.80715532286213 0.430103467392977 0.678525297697542 GO:0050811 GABA receptor binding 1/573 18/18639 0.0555555555555556 1.80715532286213 0.430103467392977 0.678525297697542 GO:0052744 phosphatidylinositol monophosphate phosphatase activity 1/573 18/18639 0.0555555555555556 1.80715532286213 0.430103467392977 0.678525297697542 GO:0099602 neurotransmitter receptor regulator activity 1/573 18/18639 0.0555555555555556 1.80715532286213 0.430103467392977 0.678525297697542 GO:1901611 phosphatidylglycerol binding 1/573 18/18639 0.0555555555555556 1.80715532286213 0.430103467392977 0.678525297697542 GO:0009378 four-way junction helicase activity 2/573 48/18639 0.0416666666666667 1.3553664921466 0.436678638909868 0.685353266899707 GO:0036121 double-stranded DNA helicase activity 2/573 48/18639 0.0416666666666667 1.3553664921466 0.436678638909868 0.685353266899707 GO:0043138 3'-5' DNA helicase activity 2/573 48/18639 0.0416666666666667 1.3553664921466 0.436678638909868 0.685353266899707 GO:0005229 intracellularly calcium-gated chloride channel activity 1/573 19/18639 0.0526315789473684 1.71204188481675 0.44764015785986 0.686345410400483 GO:0005346 purine ribonucleotide transmembrane transporter activity 1/573 19/18639 0.0526315789473684 1.71204188481675 0.44764015785986 0.686345410400483 GO:0008381 mechanosensitive monoatomic ion channel activity 1/573 19/18639 0.0526315789473684 1.71204188481675 0.44764015785986 0.686345410400483 GO:0022840 leak channel activity 1/573 19/18639 0.0526315789473684 1.71204188481675 0.44764015785986 0.686345410400483 GO:0022842 narrow pore channel activity 1/573 19/18639 0.0526315789473684 1.71204188481675 0.44764015785986 0.686345410400483 GO:0030506 ankyrin binding 1/573 19/18639 0.0526315789473684 1.71204188481675 0.44764015785986 0.686345410400483 GO:0031420 alkali metal ion binding 1/573 19/18639 0.0526315789473684 1.71204188481675 0.44764015785986 0.686345410400483 GO:0042800 histone H3K4 methyltransferase activity 1/573 19/18639 0.0526315789473684 1.71204188481675 0.44764015785986 0.686345410400483 GO:0043395 heparan sulfate proteoglycan binding 1/573 19/18639 0.0526315789473684 1.71204188481675 0.44764015785986 0.686345410400483 GO:0046527 glucosyltransferase activity 1/573 19/18639 0.0526315789473684 1.71204188481675 0.44764015785986 0.686345410400483 GO:0050145 nucleoside monophosphate kinase activity 1/573 19/18639 0.0526315789473684 1.71204188481675 0.44764015785986 0.686345410400483 GO:0070003 threonine-type peptidase activity 1/573 19/18639 0.0526315789473684 1.71204188481675 0.44764015785986 0.686345410400483 GO:0141147 intracellularly calcium-gated channel activity 1/573 19/18639 0.0526315789473684 1.71204188481675 0.44764015785986 0.686345410400483 GO:0048306 calcium-dependent protein binding 3/573 80/18639 0.0375 1.21982984293194 0.447812251376053 0.686345410400483 GO:0004252 serine-type endopeptidase activity 6/573 176/18639 0.0340909090909091 1.10893622084722 0.457115497627719 0.697705381564103 GO:0015605 organophosphate ester transmembrane transporter activity 2/573 50/18639 0.04 1.30115183246073 0.457511725615805 0.697705381564103 GO:0032813 tumor necrosis factor receptor superfamily binding 2/573 50/18639 0.04 1.30115183246073 0.457511725615805 0.697705381564103 GO:0001972 retinoic acid binding 1/573 20/18639 0.05 1.62643979057592 0.464638127223249 0.703880606637869 GO:0005326 neurotransmitter transmembrane transporter activity 1/573 20/18639 0.05 1.62643979057592 0.464638127223249 0.703880606637869 GO:0016004 phospholipase activator activity 1/573 20/18639 0.05 1.62643979057592 0.464638127223249 0.703880606637869 GO:0042288 MHC class I protein binding 1/573 20/18639 0.05 1.62643979057592 0.464638127223249 0.703880606637869 GO:0016597 amino acid binding 2/573 51/18639 0.0392156862745098 1.27563905143209 0.467759866807664 0.707438476246301 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 3/573 83/18639 0.036144578313253 1.17573960764524 0.471832593835624 0.710584557239499 GO:0005254 chloride channel activity 3/573 83/18639 0.036144578313253 1.17573960764524 0.471832593835624 0.710584557239499 GO:0101005 deubiquitinase activity 4/573 115/18639 0.0347826086956522 1.13143637605281 0.473103556549434 0.710584557239499 GO:0001846 opsonin binding 1/573 21/18639 0.0476190476190476 1.54899027673897 0.481113896765172 0.710584557239499 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 1/573 21/18639 0.0476190476190476 1.54899027673897 0.481113896765172 0.710584557239499 GO:0005123 death receptor binding 1/573 21/18639 0.0476190476190476 1.54899027673897 0.481113896765172 0.710584557239499 GO:0008373 sialyltransferase activity 1/573 21/18639 0.0476190476190476 1.54899027673897 0.481113896765172 0.710584557239499 GO:0015174 basic amino acid transmembrane transporter activity 1/573 21/18639 0.0476190476190476 1.54899027673897 0.481113896765172 0.710584557239499 GO:0019200 carbohydrate kinase activity 1/573 21/18639 0.0476190476190476 1.54899027673897 0.481113896765172 0.710584557239499 GO:0036122 BMP binding 1/573 21/18639 0.0476190476190476 1.54899027673897 0.481113896765172 0.710584557239499 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 1/573 21/18639 0.0476190476190476 1.54899027673897 0.481113896765172 0.710584557239499 GO:0070182 DNA polymerase binding 1/573 21/18639 0.0476190476190476 1.54899027673897 0.481113896765172 0.710584557239499 GO:0072542 protein phosphatase activator activity 1/573 21/18639 0.0476190476190476 1.54899027673897 0.481113896765172 0.710584557239499 GO:0016860 intramolecular oxidoreductase activity 2/573 53/18639 0.0377358490566038 1.22750172873654 0.487905166923462 0.710584557239499 GO:0140296 general transcription initiation factor binding 2/573 53/18639 0.0377358490566038 1.22750172873654 0.487905166923462 0.710584557239499 GO:1901505 carbohydrate derivative transmembrane transporter activity 2/573 53/18639 0.0377358490566038 1.22750172873654 0.487905166923462 0.710584557239499 GO:0005243 gap junction channel activity 1/573 22/18639 0.0454545454545455 1.47858162779629 0.497083481959799 0.710584557239499 GO:0015377 chloride:monoatomic cation symporter activity 1/573 22/18639 0.0454545454545455 1.47858162779629 0.497083481959799 0.710584557239499 GO:0016780 phosphotransferase activity, for other substituted phosphate groups 1/573 22/18639 0.0454545454545455 1.47858162779629 0.497083481959799 0.710584557239499 GO:0016881 acid-amino acid ligase activity 1/573 22/18639 0.0454545454545455 1.47858162779629 0.497083481959799 0.710584557239499 GO:0032931 histone H3K56 acetyltransferase activity 1/573 22/18639 0.0454545454545455 1.47858162779629 0.497083481959799 0.710584557239499 GO:0033691 sialic acid binding 1/573 22/18639 0.0454545454545455 1.47858162779629 0.497083481959799 0.710584557239499 GO:0043992 histone H3K9 acetyltransferase activity 1/573 22/18639 0.0454545454545455 1.47858162779629 0.497083481959799 0.710584557239499 GO:0043993 histone H3K18 acetyltransferase activity 1/573 22/18639 0.0454545454545455 1.47858162779629 0.497083481959799 0.710584557239499 GO:0043994 histone H3K23 acetyltransferase activity 1/573 22/18639 0.0454545454545455 1.47858162779629 0.497083481959799 0.710584557239499 GO:0043999 histone H2AK5 acetyltransferase activity 1/573 22/18639 0.0454545454545455 1.47858162779629 0.497083481959799 0.710584557239499 GO:0044012 histone H2AK9 acetyltransferase activity 1/573 22/18639 0.0454545454545455 1.47858162779629 0.497083481959799 0.710584557239499 GO:0044014 histone H2BK5 acetyltransferase activity 1/573 22/18639 0.0454545454545455 1.47858162779629 0.497083481959799 0.710584557239499 GO:0044015 histone H2BK12 acetyltransferase activity 1/573 22/18639 0.0454545454545455 1.47858162779629 0.497083481959799 0.710584557239499 GO:0044016 histone H3K4 acetyltransferase activity 1/573 22/18639 0.0454545454545455 1.47858162779629 0.497083481959799 0.710584557239499 GO:0044017 histone H3K27 acetyltransferase activity 1/573 22/18639 0.0454545454545455 1.47858162779629 0.497083481959799 0.710584557239499 GO:0044018 histone H3K36 acetyltransferase activity 1/573 22/18639 0.0454545454545455 1.47858162779629 0.497083481959799 0.710584557239499 GO:0046972 histone H4K16 acetyltransferase activity 1/573 22/18639 0.0454545454545455 1.47858162779629 0.497083481959799 0.710584557239499 GO:0070034 telomerase RNA binding 1/573 22/18639 0.0454545454545455 1.47858162779629 0.497083481959799 0.710584557239499 GO:0140908 histone H3K122 acetyltransferase activity 1/573 22/18639 0.0454545454545455 1.47858162779629 0.497083481959799 0.710584557239499 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 2/573 54/18639 0.037037037037037 1.20477021524142 0.497797487639911 0.710584557239499 GO:0008374 O-acyltransferase activity 2/573 55/18639 0.0363636363636364 1.18286530223703 0.507566792700141 0.717421053009495 GO:0016651 oxidoreductase activity, acting on NAD(P)H 3/573 88/18639 0.0340909090909091 1.10893622084722 0.510763263028108 0.717421053009495 GO:0000295 adenine nucleotide transmembrane transporter activity 1/573 23/18639 0.0434782608695652 1.41429547006601 0.512562407932675 0.717421053009495 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 1/573 23/18639 0.0434782608695652 1.41429547006601 0.512562407932675 0.717421053009495 GO:0004602 glutathione peroxidase activity 1/573 23/18639 0.0434782608695652 1.41429547006601 0.512562407932675 0.717421053009495 GO:0005212 structural constituent of eye lens 1/573 23/18639 0.0434782608695652 1.41429547006601 0.512562407932675 0.717421053009495 GO:0042171 lysophosphatidic acid acyltransferase activity 1/573 23/18639 0.0434782608695652 1.41429547006601 0.512562407932675 0.717421053009495 GO:0043274 phospholipase binding 1/573 23/18639 0.0434782608695652 1.41429547006601 0.512562407932675 0.717421053009495 GO:0044013 histone H2B acetyltransferase activity 1/573 23/18639 0.0434782608695652 1.41429547006601 0.512562407932675 0.717421053009495 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 1/573 23/18639 0.0434782608695652 1.41429547006601 0.512562407932675 0.717421053009495 GO:0071617 lysophospholipid acyltransferase activity 1/573 23/18639 0.0434782608695652 1.41429547006601 0.512562407932675 0.717421053009495 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 1/573 23/18639 0.0434782608695652 1.41429547006601 0.512562407932675 0.717421053009495 GO:0015108 chloride transmembrane transporter activity 4/573 121/18639 0.0330578512396694 1.07533209294275 0.512779637888754 0.717421053009495 GO:0030170 pyridoxal phosphate binding 2/573 56/18639 0.0357142857142857 1.16174270755423 0.517211286831636 0.72048154905997 GO:0170055 lipid transmembrane transporter activity 2/573 56/18639 0.0357142857142857 1.16174270755423 0.517211286831636 0.72048154905997 GO:0004386 helicase activity 5/573 155/18639 0.032258064516129 1.04931599391995 0.520112221820017 0.72048154905997 GO:0004601 peroxidase activity 2/573 57/18639 0.0350877192982456 1.1413612565445 0.526729400830848 0.72048154905997 GO:0015932 nucleobase-containing compound transmembrane transporter activity 2/573 57/18639 0.0350877192982456 1.1413612565445 0.526729400830848 0.72048154905997 GO:0070279 vitamin B6 binding 2/573 57/18639 0.0350877192982456 1.1413612565445 0.526729400830848 0.72048154905997 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 1/573 24/18639 0.0416666666666667 1.3553664921466 0.527565724448284 0.72048154905997 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 1/573 24/18639 0.0416666666666667 1.3553664921466 0.527565724448284 0.72048154905997 GO:0004622 lysophospholipase activity 1/573 24/18639 0.0416666666666667 1.3553664921466 0.527565724448284 0.72048154905997 GO:0004806 triacylglycerol lipase activity 1/573 24/18639 0.0416666666666667 1.3553664921466 0.527565724448284 0.72048154905997 GO:0005540 hyaluronic acid binding 1/573 24/18639 0.0416666666666667 1.3553664921466 0.527565724448284 0.72048154905997 GO:0015295 solute:proton symporter activity 1/573 24/18639 0.0416666666666667 1.3553664921466 0.527565724448284 0.72048154905997 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 1/573 24/18639 0.0416666666666667 1.3553664921466 0.527565724448284 0.72048154905997 GO:0019957 C-C chemokine binding 1/573 24/18639 0.0416666666666667 1.3553664921466 0.527565724448284 0.72048154905997 GO:0043998 histone H2A acetyltransferase activity 1/573 24/18639 0.0416666666666667 1.3553664921466 0.527565724448284 0.72048154905997 GO:0060229 lipase activator activity 1/573 24/18639 0.0416666666666667 1.3553664921466 0.527565724448284 0.72048154905997 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 3/573 91/18639 0.032967032967033 1.07237788389621 0.533382421352912 0.727339665481243 GO:0017116 single-stranded DNA helicase activity 2/573 58/18639 0.0344827586206897 1.12168261419029 0.536119779404456 0.728383023058535 GO:0061980 regulatory RNA binding 2/573 58/18639 0.0344827586206897 1.12168261419029 0.536119779404456 0.728383023058535 GO:0001848 complement binding 1/573 25/18639 0.04 1.30115183246073 0.542108020440287 0.728383023058535 GO:0003707 nuclear steroid receptor activity 1/573 25/18639 0.04 1.30115183246073 0.542108020440287 0.728383023058535 GO:0005251 delayed rectifier potassium channel activity 1/573 25/18639 0.04 1.30115183246073 0.542108020440287 0.728383023058535 GO:0008483 transaminase activity 1/573 25/18639 0.04 1.30115183246073 0.542108020440287 0.728383023058535 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 1/573 25/18639 0.04 1.30115183246073 0.542108020440287 0.728383023058535 GO:0019211 phosphatase activator activity 1/573 25/18639 0.04 1.30115183246073 0.542108020440287 0.728383023058535 GO:0047617 fatty acyl-CoA hydrolase activity 1/573 25/18639 0.04 1.30115183246073 0.542108020440287 0.728383023058535 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 1/573 25/18639 0.04 1.30115183246073 0.542108020440287 0.728383023058535 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 2/573 59/18639 0.0338983050847458 1.10267104445825 0.545381269542392 0.730635229328388 GO:0070888 E-box binding 2/573 59/18639 0.0338983050847458 1.10267104445825 0.545381269542392 0.730635229328388 GO:0015079 potassium ion transmembrane transporter activity 5/573 160/18639 0.03125 1.01652486910995 0.548384228336015 0.733584165098616 GO:0019783 ubiquitin-like protein peptidase activity 4/573 127/18639 0.031496062992126 1.02452900193759 0.551032379881713 0.735442407312163 GO:0004112 cyclic-nucleotide phosphodiesterase activity 1/573 26/18639 0.0384615384615385 1.25110753121224 0.556203438098379 0.735442407312163 GO:0005227 calcium-activated cation channel activity 1/573 26/18639 0.0384615384615385 1.25110753121224 0.556203438098379 0.735442407312163 GO:0015216 purine nucleotide transmembrane transporter activity 1/573 26/18639 0.0384615384615385 1.25110753121224 0.556203438098379 0.735442407312163 GO:0016289 acyl-CoA hydrolase activity 1/573 26/18639 0.0384615384615385 1.25110753121224 0.556203438098379 0.735442407312163 GO:0030247 polysaccharide binding 1/573 26/18639 0.0384615384615385 1.25110753121224 0.556203438098379 0.735442407312163 GO:0070006 metalloaminopeptidase activity 1/573 26/18639 0.0384615384615385 1.25110753121224 0.556203438098379 0.735442407312163 GO:0120014 phospholipid transfer activity 1/573 26/18639 0.0384615384615385 1.25110753121224 0.556203438098379 0.735442407312163 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 4/573 128/18639 0.03125 1.01652486910995 0.557253443790027 0.735767534008478 GO:0016836 hydro-lyase activity 2/573 61/18639 0.0327868852459016 1.06651789545962 0.56351391767942 0.742796721466869 GO:0000287 magnesium ion binding 7/573 230/18639 0.0304347826086957 0.99000682904621 0.564200788436583 0.742796721466869 GO:0016407 acetyltransferase activity 3/573 96/18639 0.03125 1.01652486910995 0.569728965163334 0.74489586167231 GO:0005044 scavenger receptor activity 1/573 27/18639 0.037037037037037 1.20477021524142 0.569865686525265 0.74489586167231 GO:0008266 poly(U) RNA binding 1/573 27/18639 0.037037037037037 1.20477021524142 0.569865686525265 0.74489586167231 GO:0015252 proton channel activity 1/573 27/18639 0.037037037037037 1.20477021524142 0.569865686525265 0.74489586167231 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 1/573 27/18639 0.037037037037037 1.20477021524142 0.569865686525265 0.74489586167231 GO:0031072 heat shock protein binding 4/573 131/18639 0.0305343511450382 0.993245673634147 0.575634406396012 0.750554067766539 GO:0015103 inorganic anion transmembrane transporter activity 5/573 165/18639 0.0303030303030303 0.985721085197525 0.575834924122525 0.750554067766539 GO:0005507 copper ion binding 2/573 63/18639 0.0317460317460317 1.03266018449265 0.581121756507149 0.752530141472247 GO:0036408 histone H3K14 acetyltransferase activity 1/573 28/18639 0.0357142857142857 1.16174270755423 0.583108054976856 0.752530141472247 GO:0046875 ephrin receptor binding 1/573 28/18639 0.0357142857142857 1.16174270755423 0.583108054976856 0.752530141472247 GO:0046966 nuclear thyroid hormone receptor binding 1/573 28/18639 0.0357142857142857 1.16174270755423 0.583108054976856 0.752530141472247 GO:0050698 proteoglycan sulfotransferase activity 1/573 28/18639 0.0357142857142857 1.16174270755423 0.583108054976856 0.752530141472247 GO:0051019 mitogen-activated protein kinase binding 1/573 28/18639 0.0357142857142857 1.16174270755423 0.583108054976856 0.752530141472247 GO:0051537 2 iron, 2 sulfur cluster binding 1/573 28/18639 0.0357142857142857 1.16174270755423 0.583108054976856 0.752530141472247 GO:0004181 metallocarboxypeptidase activity 1/573 29/18639 0.0344827586206897 1.12168261419029 0.595943425698379 0.765854261957889 GO:0010484 histone H3 acetyltransferase activity 1/573 29/18639 0.0344827586206897 1.12168261419029 0.595943425698379 0.765854261957889 GO:0035250 UDP-galactosyltransferase activity 1/573 29/18639 0.0344827586206897 1.12168261419029 0.595943425698379 0.765854261957889 GO:0008235 metalloexopeptidase activity 2/573 66/18639 0.0303030303030303 0.985721085197525 0.606543535382692 0.771013326907712 GO:0001965 G-protein alpha-subunit binding 1/573 30/18639 0.0333333333333333 1.08429319371728 0.608384286368708 0.771013326907712 GO:0008187 poly-pyrimidine tract binding 1/573 30/18639 0.0333333333333333 1.08429319371728 0.608384286368708 0.771013326907712 GO:0015215 nucleotide transmembrane transporter activity 1/573 30/18639 0.0333333333333333 1.08429319371728 0.608384286368708 0.771013326907712 GO:0016769 transferase activity, transferring nitrogenous groups 1/573 30/18639 0.0333333333333333 1.08429319371728 0.608384286368708 0.771013326907712 GO:0022839 monoatomic ion-gated channel activity 1/573 30/18639 0.0333333333333333 1.08429319371728 0.608384286368708 0.771013326907712 GO:0043995 histone H4K5 acetyltransferase activity 1/573 30/18639 0.0333333333333333 1.08429319371728 0.608384286368708 0.771013326907712 GO:0043996 histone H4K8 acetyltransferase activity 1/573 30/18639 0.0333333333333333 1.08429319371728 0.608384286368708 0.771013326907712 GO:0043997 histone H4K12 acetyltransferase activity 1/573 30/18639 0.0333333333333333 1.08429319371728 0.608384286368708 0.771013326907712 GO:0048019 receptor antagonist activity 1/573 30/18639 0.0333333333333333 1.08429319371728 0.608384286368708 0.771013326907712 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 2/573 67/18639 0.0298507462686567 0.971008830194577 0.614753232995124 0.776614376307598 GO:0042054 histone methyltransferase activity 2/573 67/18639 0.0298507462686567 0.971008830194577 0.614753232995124 0.776614376307598 GO:0004722 protein serine/threonine phosphatase activity 3/573 103/18639 0.029126213592233 0.947440654704417 0.61757083140521 0.776614376307598 GO:0140030 modification-dependent protein binding 5/573 173/18639 0.0289017341040462 0.940138607269316 0.617852324852813 0.776614376307598 GO:0005164 tumor necrosis factor receptor binding 1/573 31/18639 0.032258064516129 1.04931599391995 0.620442742164868 0.776614376307598 GO:0005184 neuropeptide hormone activity 1/573 31/18639 0.032258064516129 1.04931599391995 0.620442742164868 0.776614376307598 GO:0005452 solute:inorganic anion antiporter activity 1/573 31/18639 0.032258064516129 1.04931599391995 0.620442742164868 0.776614376307598 GO:0016411 acylglycerol O-acyltransferase activity 1/573 31/18639 0.032258064516129 1.04931599391995 0.620442742164868 0.776614376307598 GO:0017147 Wnt-protein binding 1/573 31/18639 0.032258064516129 1.04931599391995 0.620442742164868 0.776614376307598 GO:0030145 manganese ion binding 2/573 68/18639 0.0294117647058824 0.956729288574068 0.622831086729267 0.777476731728894 GO:0140223 general transcription initiation factor activity 2/573 68/18639 0.0294117647058824 0.956729288574068 0.622831086729267 0.777476731728894 GO:0005216 monoatomic ion channel activity 13/573 448/18639 0.0290178571428571 0.943915949887809 0.623791137678259 0.777614292882298 GO:0001217 DNA-binding transcription repressor activity 8/573 278/18639 0.0287769784172662 0.936080455007722 0.624957082357118 0.778007796403759 GO:0008080 N-acetyltransferase activity 2/573 69/18639 0.0289855072463768 0.942863646710676 0.630777429784272 0.781620854897719 GO:0016279 protein-lysine N-methyltransferase activity 2/573 69/18639 0.0289855072463768 0.942863646710676 0.630777429784272 0.781620854897719 GO:0008378 galactosyltransferase activity 1/573 32/18639 0.03125 1.01652486910995 0.632130527458264 0.781620854897719 GO:0051059 NF-kappaB binding 1/573 32/18639 0.03125 1.01652486910995 0.632130527458264 0.781620854897719 GO:0160041 neuropeptide activity 1/573 32/18639 0.03125 1.01652486910995 0.632130527458264 0.781620854897719 GO:0016887 ATP hydrolysis activity 12/573 417/18639 0.0287769784172662 0.936080455007722 0.633370706241976 0.782097430784626 GO:0004497 monooxygenase activity 3/573 106/18639 0.0283018867924528 0.920626296552405 0.636939133936612 0.785366021358376 GO:0016278 lysine N-methyltransferase activity 2/573 70/18639 0.0285714285714286 0.929394166043381 0.638592699334024 0.785366021358376 GO:0016782 transferase activity, transferring sulphur-containing groups 2/573 70/18639 0.0285714285714286 0.929394166043381 0.638592699334024 0.785366021358376 GO:0019888 protein phosphatase regulator activity 3/573 107/18639 0.0280373831775701 0.912022312472476 0.643240992865515 0.788172691694518 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 1/573 33/18639 0.0303030303030303 0.985721085197525 0.643459017153886 0.788172691694518 GO:0140311 protein sequestering activity 1/573 33/18639 0.0303030303030303 0.985721085197525 0.643459017153886 0.788172691694518 GO:0008175 tRNA methyltransferase activity 1/573 34/18639 0.0294117647058824 0.956729288574068 0.654439237683329 0.797352732996333 GO:0015020 glucuronosyltransferase activity 1/573 34/18639 0.0294117647058824 0.956729288574068 0.654439237683329 0.797352732996333 GO:0019825 oxygen binding 1/573 34/18639 0.0294117647058824 0.956729288574068 0.654439237683329 0.797352732996333 GO:0030332 cyclin binding 1/573 34/18639 0.0294117647058824 0.956729288574068 0.654439237683329 0.797352732996333 GO:0004521 RNA endonuclease activity 2/573 73/18639 0.0273972602739726 0.891199885247077 0.661257860084715 0.80458901858712 GO:0010485 histone H4 acetyltransferase activity 1/573 35/18639 0.0285714285714286 0.929394166043381 0.66508187766223 0.808167221860479 GO:0003678 DNA helicase activity 2/573 74/18639 0.027027027027027 0.879156643554549 0.668555059308993 0.81023560167911 GO:0035064 methylated histone binding 2/573 74/18639 0.027027027027027 0.879156643554549 0.668555059308993 0.81023560167911 GO:0004190 aspartic-type endopeptidase activity 1/573 36/18639 0.0277777777777778 0.903577661431065 0.6753972982223 0.814608836702373 GO:0016409 palmitoyltransferase activity 1/573 36/18639 0.0277777777777778 0.903577661431065 0.6753972982223 0.814608836702373 GO:0055106 ubiquitin-protein transferase regulator activity 1/573 36/18639 0.0277777777777778 0.903577661431065 0.6753972982223 0.814608836702373 GO:0019003 GDP binding 2/573 75/18639 0.0266666666666667 0.867434554973822 0.675724707166231 0.814608836702373 GO:0017022 myosin binding 2/573 76/18639 0.0263157894736842 0.856020942408377 0.682767734750968 0.816581272889224 GO:0140034 methylation-dependent protein binding 2/573 76/18639 0.0263157894736842 0.856020942408377 0.682767734750968 0.816581272889224 GO:0008234 cysteine-type peptidase activity 5/573 187/18639 0.0267379679144385 0.869753898703699 0.685141778392312 0.816581272889224 GO:0022829 wide pore channel activity 1/573 37/18639 0.027027027027027 0.879156643554549 0.685395543027902 0.816581272889224 GO:0030280 structural constituent of skin epidermis 1/573 37/18639 0.027027027027027 0.879156643554549 0.685395543027902 0.816581272889224 GO:0070001 aspartic-type peptidase activity 1/573 37/18639 0.027027027027027 0.879156643554549 0.685395543027902 0.816581272889224 GO:0000510 H3-H4 histone complex chaperone activity 4/573 151/18639 0.0264900662251656 0.861689955272009 0.68628524464679 0.816581272889224 GO:0140584 chromatin extrusion motor activity 4/573 151/18639 0.0264900662251656 0.861689955272009 0.68628524464679 0.816581272889224 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 4/573 151/18639 0.0264900662251656 0.861689955272009 0.68628524464679 0.816581272889224 GO:0140849 ATP-dependent H2AZ histone chaperone activity 4/573 151/18639 0.0264900662251656 0.861689955272009 0.68628524464679 0.816581272889224 GO:0003724 RNA helicase activity 2/573 77/18639 0.025974025974026 0.844903787312164 0.689685136446203 0.819285851698756 GO:0015616 DNA translocase activity 4/573 152/18639 0.0263157894736842 0.856020942408377 0.691244456296656 0.819285851698756 GO:0140674 ATP-dependent histone chaperone activity 4/573 152/18639 0.0263157894736842 0.856020942408377 0.691244456296656 0.819285851698756 GO:0005109 frizzled binding 1/573 38/18639 0.0263157894736842 0.856020942408377 0.695086347986778 0.821115412693076 GO:0042162 telomeric DNA binding 1/573 38/18639 0.0263157894736842 0.856020942408377 0.695086347986778 0.821115412693076 GO:0061775 cohesin loader activity 4/573 153/18639 0.0261437908496732 0.850426034288061 0.696147808102379 0.821115412693076 GO:0001664 G protein-coupled receptor binding 8/573 297/18639 0.0269360269360269 0.876196520175578 0.696876322916033 0.821115412693076 GO:0005506 iron ion binding 4/573 154/18639 0.025974025974026 0.844903787312164 0.700995283023358 0.821115412693076 GO:0046982 protein heterodimerization activity 10/573 369/18639 0.02710027100271 0.881539181883966 0.701703938164555 0.821115412693076 GO:0019208 phosphatase regulator activity 3/573 117/18639 0.0256410256410256 0.834071687474829 0.701989755723452 0.821115412693076 GO:0008186 ATP-dependent activity, acting on RNA 2/573 79/18639 0.0253164556962025 0.823513818013122 0.703147327835192 0.821115412693076 GO:0016835 carbon-oxygen lyase activity 2/573 79/18639 0.0253164556962025 0.823513818013122 0.703147327835192 0.821115412693076 GO:0000217 DNA secondary structure binding 1/573 39/18639 0.0256410256410256 0.834071687474829 0.704479150664246 0.821115412693076 GO:0016776 phosphotransferase activity, phosphate group as acceptor 1/573 39/18639 0.0256410256410256 0.834071687474829 0.704479150664246 0.821115412693076 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 6/573 229/18639 0.0262008733624454 0.852282859690436 0.709969539048676 0.821115412693076 GO:0004177 aminopeptidase activity 1/573 40/18639 0.025 0.813219895287958 0.713583099409912 0.821115412693076 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 1/573 40/18639 0.025 0.813219895287958 0.713583099409912 0.821115412693076 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 1/573 40/18639 0.025 0.813219895287958 0.713583099409912 0.821115412693076 GO:0061791 GTPase motor activity 1/573 40/18639 0.025 0.813219895287958 0.713583099409912 0.821115412693076 GO:0071855 neuropeptide receptor binding 1/573 40/18639 0.025 0.813219895287958 0.713583099409912 0.821115412693076 GO:1990606 membrane scission GTPase motor activity 1/573 40/18639 0.025 0.813219895287958 0.713583099409912 0.821115412693076 GO:0033192 calmodulin-dependent protein phosphatase activity 2/573 81/18639 0.0246913580246914 0.80318014349428 0.7161203271356 0.821115412693076 GO:0140791 histone H2AXS140 phosphatase activity 2/573 81/18639 0.0246913580246914 0.80318014349428 0.7161203271356 0.821115412693076 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 2/573 81/18639 0.0246913580246914 0.80318014349428 0.7161203271356 0.821115412693076 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 2/573 81/18639 0.0246913580246914 0.80318014349428 0.7161203271356 0.821115412693076 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 2/573 81/18639 0.0246913580246914 0.80318014349428 0.7161203271356 0.821115412693076 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 2/573 81/18639 0.0246913580246914 0.80318014349428 0.7161203271356 0.821115412693076 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 2/573 81/18639 0.0246913580246914 0.80318014349428 0.7161203271356 0.821115412693076 GO:1990439 MAP kinase serine/threonine phosphatase activity 2/573 81/18639 0.0246913580246914 0.80318014349428 0.7161203271356 0.821115412693076 GO:0140658 ATP-dependent chromatin remodeler activity 4/573 158/18639 0.0253164556962025 0.823513818013122 0.719826872672808 0.822164384489911 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 7/573 268/18639 0.0261194029850746 0.849632726420255 0.720788692786825 0.822164384489911 GO:0008137 NADH dehydrogenase (ubiquinone) activity 1/573 41/18639 0.024390243902439 0.793385263695569 0.72240706220566 0.822164384489911 GO:0042287 MHC protein binding 1/573 41/18639 0.024390243902439 0.793385263695569 0.72240706220566 0.822164384489911 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 2/573 82/18639 0.024390243902439 0.793385263695569 0.72242640997802 0.822164384489911 GO:0033549 MAP kinase phosphatase activity 2/573 82/18639 0.024390243902439 0.793385263695569 0.72242640997802 0.822164384489911 GO:0005261 monoatomic cation channel activity 9/573 341/18639 0.0263929618768328 0.858531267752683 0.725119479768508 0.824204129177869 GO:0003689 DNA clamp loader activity 4/573 160/18639 0.025 0.813219895287958 0.728908606733215 0.825713662034227 GO:0004842 ubiquitin-protein transferase activity 12/573 449/18639 0.0267260579064588 0.869366480486013 0.729860798884067 0.825713662034227 GO:0004402 histone acetyltransferase activity 1/573 42/18639 0.0238095238095238 0.774495138369484 0.730959635243415 0.825713662034227 GO:0035198 miRNA binding 1/573 42/18639 0.0238095238095238 0.774495138369484 0.730959635243415 0.825713662034227 GO:0048487 beta-tubulin binding 1/573 42/18639 0.0238095238095238 0.774495138369484 0.730959635243415 0.825713662034227 GO:0004860 protein kinase inhibitor activity 2/573 84/18639 0.0238095238095238 0.774495138369484 0.734684148573759 0.827876842296786 GO:0017018 myosin phosphatase activity 2/573 84/18639 0.0238095238095238 0.774495138369484 0.734684148573759 0.827876842296786 GO:0008083 growth factor activity 4/573 162/18639 0.0246913580246914 0.80318014349428 0.73776882322554 0.830330225401438 GO:0140713 histone chaperone activity 4/573 164/18639 0.024390243902439 0.793385263695569 0.746408788681097 0.835898012305256 GO:0003954 NADH dehydrogenase activity 1/573 44/18639 0.0227272727272727 0.739290813898144 0.747283687503496 0.835898012305256 GO:0016790 thiolester hydrolase activity 1/573 44/18639 0.0227272727272727 0.739290813898144 0.747283687503496 0.835898012305256 GO:0030547 signaling receptor inhibitor activity 1/573 44/18639 0.0227272727272727 0.739290813898144 0.747283687503496 0.835898012305256 GO:0043014 alpha-tubulin binding 1/573 44/18639 0.0227272727272727 0.739290813898144 0.747283687503496 0.835898012305256 GO:0042605 peptide antigen binding 1/573 45/18639 0.0222222222222222 0.722862129144852 0.755071073739608 0.843577573225569 GO:0016755 aminoacyltransferase activity 13/573 496/18639 0.0262096774193548 0.852569245059956 0.759867017797328 0.847900391810434 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 1/573 46/18639 0.0217391304347826 0.707147735033007 0.762618899637597 0.84968598044261 GO:0003727 single-stranded RNA binding 2/573 89/18639 0.0224719101123595 0.730984175539738 0.763324454561558 0.84968598044261 GO:0022836 gated channel activity 8/573 318/18639 0.0251572327044025 0.81833448582436 0.765370608113732 0.850928440369459 GO:0019210 kinase inhibitor activity 2/573 90/18639 0.0222222222222222 0.722862129144852 0.768720286581084 0.851862258552701 GO:0043495 protein-membrane adaptor activity 1/573 47/18639 0.0212765957446809 0.692102038542943 0.76993452221102 0.851862258552701 GO:0061733 protein-lysine-acetyltransferase activity 1/573 47/18639 0.0212765957446809 0.692102038542943 0.76993452221102 0.851862258552701 GO:0099095 ligand-gated monoatomic anion channel activity 1/573 47/18639 0.0212765957446809 0.692102038542943 0.76993452221102 0.851862258552701 GO:0005262 calcium channel activity 3/573 131/18639 0.0229007633587786 0.744934255225611 0.771441670108608 0.85249894704031 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 1/573 48/18639 0.0208333333333333 0.677683246073298 0.777025072919555 0.854810445679579 GO:0016879 ligase activity, forming carbon-nitrogen bonds 1/573 48/18639 0.0208333333333333 0.677683246073298 0.777025072919555 0.854810445679579 GO:0140693 molecular condensate scaffold activity 1/573 48/18639 0.0208333333333333 0.677683246073298 0.777025072919555 0.854810445679579 GO:0008094 ATP-dependent activity, acting on DNA 5/573 210/18639 0.0238095238095238 0.774495138369484 0.777270263175312 0.854810445679579 GO:0016763 pentosyltransferase activity 1/573 49/18639 0.0204081632653061 0.663852975745272 0.783897464572349 0.861063841637094 GO:0016779 nucleotidyltransferase activity 3/573 136/18639 0.0220588235294118 0.717546966430551 0.792813722099099 0.868771923018773 GO:0099094 ligand-gated monoatomic cation channel activity 3/573 136/18639 0.0220588235294118 0.717546966430551 0.792813722099099 0.868771923018773 GO:0008276 protein methyltransferase activity 2/573 95/18639 0.0210526315789474 0.684816753926701 0.794119208766366 0.869161574188068 GO:0005048 signal sequence binding 1/573 51/18639 0.0196078431372549 0.637819525716045 0.797014368644698 0.86921114101299 GO:0005272 sodium channel activity 1/573 51/18639 0.0196078431372549 0.637819525716045 0.797014368644698 0.86921114101299 GO:0016830 carbon-carbon lyase activity 1/573 51/18639 0.0196078431372549 0.637819525716045 0.797014368644698 0.86921114101299 GO:0019787 ubiquitin-like protein transferase activity 12/573 479/18639 0.0250521920668058 0.814917640372067 0.803946894010861 0.873281625027388 GO:0140101 catalytic activity, acting on a tRNA 3/573 139/18639 0.0215827338129496 0.702060341255791 0.804820784299139 0.873281625027388 GO:0016853 isomerase activity 4/573 180/18639 0.0222222222222222 0.722862129144852 0.807833103033924 0.873281625027388 GO:0008170 N-methyltransferase activity 2/573 98/18639 0.0204081632653061 0.663852975745272 0.808148587711834 0.873281625027388 GO:0004864 protein phosphatase inhibitor activity 1/573 53/18639 0.0188679245283019 0.61375086436827 0.809336413140137 0.873281625027388 GO:0005246 calcium channel regulator activity 1/573 53/18639 0.0188679245283019 0.61375086436827 0.809336413140137 0.873281625027388 GO:0008146 sulfotransferase activity 1/573 53/18639 0.0188679245283019 0.61375086436827 0.809336413140137 0.873281625027388 GO:0016251 RNA polymerase II general transcription initiation factor activity 1/573 53/18639 0.0188679245283019 0.61375086436827 0.809336413140137 0.873281625027388 GO:0034212 protein N-acetyltransferase activity 1/573 53/18639 0.0188679245283019 0.61375086436827 0.809336413140137 0.873281625027388 GO:0050661 NADP binding 1/573 54/18639 0.0185185185185185 0.60238510762071 0.815214506074103 0.877554438891535 GO:0051287 NAD binding 1/573 54/18639 0.0185185185185185 0.60238510762071 0.815214506074103 0.877554438891535 GO:0140313 molecular sequestering activity 1/573 55/18639 0.0181818181818182 0.591432651118515 0.820911685951399 0.882648875024124 GO:0019212 phosphatase inhibitor activity 1/573 56/18639 0.0178571428571429 0.580871353777113 0.82643351138994 0.887543031598351 GO:0015276 ligand-gated monoatomic ion channel activity 4/573 186/18639 0.021505376344086 0.699543995946631 0.827510804891445 0.887658131858936 GO:0016504 peptidase activator activity 1/573 57/18639 0.0175438596491228 0.570680628272251 0.831785370507067 0.88935635527543 GO:0022834 ligand-gated channel activity 4/573 188/18639 0.0212765957446809 0.692102038542943 0.833687799590142 0.88935635527543 GO:0046943 carboxylic acid transmembrane transporter activity 4/573 188/18639 0.0212765957446809 0.692102038542943 0.833687799590142 0.88935635527543 GO:0140597 protein carrier chaperone 4/573 188/18639 0.0212765957446809 0.692102038542943 0.833687799590142 0.88935635527543 GO:0015085 calcium ion transmembrane transporter activity 3/573 147/18639 0.0204081632653061 0.663852975745272 0.834005648494909 0.88935635527543 GO:0022804 active transmembrane transporter activity 11/573 457/18639 0.0240700218818381 0.782968826973089 0.834925802384256 0.88935635527543 GO:0005342 organic acid transmembrane transporter activity 4/573 189/18639 0.0211640211640212 0.688440122995097 0.836706551575273 0.889465534051693 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 1/573 58/18639 0.0172413793103448 0.560841307095143 0.836972486140446 0.889465534051693 GO:0031593 polyubiquitin modification-dependent protein binding 1/573 59/18639 0.0169491525423729 0.551335522229124 0.841999920909378 0.891701305129723 GO:0036002 pre-mRNA binding 1/573 59/18639 0.0169491525423729 0.551335522229124 0.841999920909378 0.891701305129723 GO:0070063 RNA polymerase binding 1/573 59/18639 0.0169491525423729 0.551335522229124 0.841999920909378 0.891701305129723 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 1/573 60/18639 0.0166666666666667 0.542146596858639 0.846872582121376 0.895824754498334 GO:0005125 cytokine activity 5/573 234/18639 0.0213675213675214 0.695059739562357 0.849779984457111 0.897706949624192 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 1/573 61/18639 0.0163934426229508 0.533258947729809 0.851595226528742 0.897706949624192 GO:0019905 syntaxin binding 1/573 61/18639 0.0163934426229508 0.533258947729809 0.851595226528742 0.897706949624192 GO:0061630 ubiquitin protein ligase activity 8/573 353/18639 0.0226628895184136 0.737196505643475 0.853542099039833 0.898723844213403 GO:0016829 lyase activity 4/573 200/18639 0.02 0.650575916230367 0.866982075255486 0.911825975699735 GO:0009055 electron transfer activity 2/573 116/18639 0.0172413793103448 0.560841307095143 0.875728469439364 0.919967335863396 GO:0008173 RNA methyltransferase activity 1/573 67/18639 0.0149253731343284 0.485504415097288 0.877029281160331 0.920277284703788 GO:0042393 histone binding 5/573 247/18639 0.0202429149797571 0.658477648006444 0.880125063037583 0.922143369470244 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 1/573 68/18639 0.0147058823529412 0.478364644287034 0.880823284062287 0.922143369470244 GO:0140104 molecular carrier activity 5/573 249/18639 0.0200803212851406 0.653188670914023 0.884297422095916 0.923878872734017 GO:0002039 p53 binding 1/573 69/18639 0.0144927536231884 0.471431823355338 0.884500428978141 0.923878872734017 GO:0061659 ubiquitin-like protein ligase activity 8/573 372/18639 0.021505376344086 0.699543995946631 0.888978826400154 0.927497863347937 GO:0004540 RNA nuclease activity 2/573 121/18639 0.0165289256198347 0.537666046471377 0.890170164204703 0.927515997111764 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 3/573 167/18639 0.0179640718562874 0.584349625356617 0.891023564438514 0.927515997111764 GO:0044183 protein folding chaperone 1/573 75/18639 0.0133333333333333 0.433717277486911 0.904302966052698 0.939318508727964 GO:0004519 endonuclease activity 2/573 127/18639 0.015748031496063 0.512264500968793 0.905441447757447 0.939318508727964 GO:0042826 histone deacetylase binding 2/573 127/18639 0.015748031496063 0.512264500968793 0.905441447757447 0.939318508727964 GO:0051536 iron-sulfur cluster binding 1/573 76/18639 0.0131578947368421 0.428010471204189 0.907256769136721 0.940135836647904 GO:0003730 mRNA 3'-UTR binding 5/573 262/18639 0.0190839694656489 0.620778546021342 0.908496493067788 0.940355532983061 GO:0051540 metal cluster binding 1/573 77/18639 0.012987012987013 0.422451893656082 0.910119553777386 0.940971064074924 GO:0043021 ribonucleoprotein complex binding 3/573 177/18639 0.0169491525423729 0.551335522229124 0.91236755415082 0.942230600505644 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 2/573 132/18639 0.0151515151515152 0.492860542598763 0.916628016356604 0.94556328632051 GO:0000049 tRNA binding 1/573 80/18639 0.0125 0.406609947643979 0.918189368644072 0.946107288636629 GO:0051087 protein-folding chaperone binding 2/573 134/18639 0.0149253731343284 0.485504415097288 0.920744831971578 0.947673252254211 GO:0015297 antiporter activity 2/573 135/18639 0.0148148148148148 0.481908086096568 0.922730813419219 0.948650218290546 GO:0008135 translation factor activity, RNA binding 1/573 83/18639 0.0120481927710843 0.391913202548414 0.925535794614455 0.950466051708447 GO:0015078 proton transmembrane transporter activity 3/573 185/18639 0.0162162162162162 0.52749398613273 0.926629297477315 0.95052220537191 GO:0180051 translation factor activity 1/573 84/18639 0.0119047619047619 0.387247569184742 0.927835212036632 0.950693414348844 GO:0020037 heme binding 2/573 142/18639 0.0140845070422535 0.458152053683357 0.935373800260153 0.957269438004019 GO:0004197 cysteine-type endopeptidase activity 1/573 88/18639 0.0113636363636364 0.369645406949072 0.936345515861855 0.957269438004019 GO:0046906 tetrapyrrole binding 2/573 152/18639 0.0131578947368421 0.428010471204189 0.950079551510816 0.970226327714728 GO:0008168 methyltransferase activity 3/573 204/18639 0.0147058823529412 0.478364644287034 0.952380823490155 0.971492144362867 GO:0140098 catalytic activity, acting on RNA 7/573 387/18639 0.0180878552971576 0.58837615162953 0.955511495947912 0.97360024364403 GO:0016741 transferase activity, transferring one-carbon groups 3/573 215/18639 0.013953488372093 0.453890174114209 0.963148492050793 0.980290178227448 GO:0016874 ligase activity 2/573 167/18639 0.0119760479041916 0.389566416904411 0.966305084005786 0.982410168739215 GO:0022853 active monoatomic ion transmembrane transporter activity 1/573 118/18639 0.00847457627118644 0.275667761114562 0.975184353457195 0.988456310791315 GO:0003697 single-stranded DNA binding 1/573 121/18639 0.00826446280991736 0.268833023235689 0.977417176718542 0.988456310791315 GO:0051082 unfolded protein binding 1/573 121/18639 0.00826446280991736 0.268833023235689 0.977417176718542 0.988456310791315 GO:0008528 G protein-coupled peptide receptor activity 1/573 122/18639 0.00819672131147541 0.266629473864904 0.97811595400228 0.988456310791315 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/573 122/18639 0.00819672131147541 0.266629473864904 0.97811595400228 0.988456310791315 GO:0140097 catalytic activity, acting on DNA 5/573 336/18639 0.0148809523809524 0.484059461480927 0.978733789701565 0.988456310791315 GO:0001653 peptide receptor activity 1/573 128/18639 0.0078125 0.254131217277487 0.981877914020613 0.990538358686727 GO:0019001 guanyl nucleotide binding 6/573 400/18639 0.015 0.487931937172775 0.985106331428787 0.99160868345142 GO:0032561 guanyl ribonucleotide binding 6/573 400/18639 0.015 0.487931937172775 0.985106331428787 0.99160868345142 GO:0004518 nuclease activity 2/573 209/18639 0.00956937799043062 0.311280342693955 0.989123703480889 0.99455844910441 GO:0005525 GTP binding 5/573 378/18639 0.0132275132275132 0.430275076871936 0.9913860319994 0.995299770509282 GO:0003924 GTPase activity 4/573 331/18639 0.0120845921450151 0.393097230350675 0.992036492573186 0.995299770509282 GO:0015399 primary active transmembrane transporter activity 1/573 166/18639 0.00602409638554217 0.195956601274207 0.994520286086388 0.996698862835756 GO:0003823 antigen binding 1/573 174/18639 0.00574712643678161 0.186947102365048 0.995741451345886 0.996830884006002 GO:0045182 translation regulator activity 3/573 356/18639 0.00842696629213483 0.274119065827402 0.998952381222552 0.998952381222552