ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0003779	actin binding	45/335	443/18639	0.101580135440181	5.65179744617769	2.88940093021245e-21	1.99368664184659e-18
GO:0005201	extracellular matrix structural constituent	24/335	168/18639	0.142857142857143	7.94840085287847	4.01245686839892e-15	1.38429761959763e-12
GO:0008201	heparin binding	20/335	172/18639	0.116279069767442	6.46962860118015	3.96195142057089e-11	9.11248826731305e-09
GO:0005539	glycosaminoglycan binding	23/335	242/18639	0.0950413223140496	5.28798569137782	8.50473834312688e-11	1.46706736418939e-08
GO:0045296	cadherin binding	26/335	334/18639	0.0778443113772455	4.33116453659845	4.0629495787042e-10	5.6068704186118e-08
GO:1901681	sulfur compound binding	21/335	275/18639	0.0763636363636364	4.2487815468114	2.87207361922289e-08	3.30288466210633e-06
GO:0005520	insulin-like growth factor binding	6/335	19/18639	0.315789473684211	17.5701492537313	7.1788643833576e-07	7.07630917788106e-05
GO:0019838	growth factor binding	13/335	136/18639	0.0955882352941176	5.31841527655838	1.07615349681668e-06	9.02896472253725e-05
GO:0051015	actin filament binding	16/335	209/18639	0.076555023923445	4.25943012211669	1.27107657980853e-06	9.02896472253725e-05
GO:0005178	integrin binding	14/335	161/18639	0.0869565217391304	4.83815704088254	1.30854561196192e-06	9.02896472253725e-05
GO:0031994	insulin-like growth factor I binding	5/335	13/18639	0.384615384615385	21.3995407577497	2.0811992474945e-06	0.000130547952797383
GO:0030020	extracellular matrix structural constituent conferring tensile strength	7/335	44/18639	0.159090909090909	8.85162822252375	1.23133674304484e-05	0.000655293882228959
GO:0098641	cadherin binding involved in cell-cell adhesion	5/335	18/18639	0.277777777777778	15.455223880597	1.28663565715043e-05	0.000655293882228959
GO:0001968	fibronectin binding	6/335	30/18639	0.2	11.1277611940299	1.32958179002977e-05	0.000655293882228959
GO:0070325	lipoprotein particle receptor binding	6/335	31/18639	0.193548387096774	10.7688011555128	1.6239001462885e-05	0.000746994067292709
GO:0050840	extracellular matrix binding	8/335	67/18639	0.119402985074627	6.64343951882379	2.59685048811302e-05	0.00111989177299874
GO:0005518	collagen binding	8/335	72/18639	0.111111111111111	6.18208955223881	4.40866423386341e-05	0.00178939901256809
GO:0043394	proteoglycan binding	6/335	37/18639	0.162162162162162	9.02250907624042	4.68247827659559e-05	0.00179495000602831
GO:0004867	serine-type endopeptidase inhibitor activity	9/335	95/18639	0.0947368421052632	5.2710447761194	5.31743726812411e-05	0.00193106932368718
GO:0043560	insulin receptor substrate binding	4/335	13/18639	0.307692307692308	17.1196326061998	6.44637780407312e-05	0.00222400034240523
GO:0043548	phosphatidylinositol 3-kinase binding	5/335	26/18639	0.192307692307692	10.6997703788749	8.77709943098861e-05	0.0028839040987534
GO:0055102	lipase inhibitor activity	4/335	16/18639	0.25	13.9097014925373	0.0001572319077666	0.00488169525189623
GO:0004866	endopeptidase inhibitor activity	11/335	161/18639	0.0683229813664596	3.80140910355057	0.000162723175063208	0.00488169525189623
GO:0071813	lipoprotein particle binding	5/335	32/18639	0.15625	8.69356343283582	0.00024597301934725	0.00659543212920386
GO:0071814	protein-lipid complex binding	5/335	32/18639	0.15625	8.69356343283582	0.00024597301934725	0.00659543212920386
GO:0030414	peptidase inhibitor activity	11/335	169/18639	0.0650887573964497	3.62146074361918	0.000248523529506232	0.00659543212920386
GO:0005543	phospholipid binding	21/335	497/18639	0.0422535211267606	2.35093546352743	0.000276776797800491	0.00707318483267922
GO:0098631	cell adhesion mediator activity	7/335	76/18639	0.0921052631578947	5.12462686567164	0.000429951170655509	0.0105916719628041
GO:0098632	cell-cell adhesion mediator activity	6/335	55/18639	0.109090909090909	6.06968792401628	0.000445157227422203	0.0105916719628041
GO:0042805	actinin binding	5/335	37/18639	0.135135135135135	7.51875756353368	0.000494717606441571	0.0110704136292697
GO:0019199	transmembrane receptor protein kinase activity	7/335	78/18639	0.0897435897435897	4.99322617680827	0.00050394040045432	0.0110704136292697
GO:0061135	endopeptidase regulator activity	11/335	184/18639	0.0597826086956522	3.32623296560675	0.000513410487154536	0.0110704136292697
GO:0004857	enzyme inhibitor activity	18/335	416/18639	0.0432692307692308	2.40744833524684	0.000567399505641167	0.0118638078452244
GO:0004955	prostaglandin receptor activity	3/335	10/18639	0.3	16.6916417910448	0.00062868466878564	0.012758600631238
GO:0140272	exogenous protein binding	7/335	82/18639	0.0853658536585366	4.74965416818347	0.000682228698588802	0.0132761061151747
GO:0005158	insulin receptor binding	4/335	23/18639	0.173913043478261	9.67631408176509	0.000692666406009116	0.0132761061151747
GO:0061134	peptidase regulator activity	12/335	226/18639	0.0530973451327434	2.95427288337076	0.000833907751469208	0.0154879878785337
GO:0004954	prostanoid receptor activity	3/335	11/18639	0.272727272727273	15.1742198100407	0.000852961651281567	0.0154879878785337
GO:0008307	structural constituent of muscle	5/335	42/18639	0.119047619047619	6.62366737739872	0.00089721527977485	0.0158738087960166
GO:0043178	alcohol binding	7/335	92/18639	0.0760869565217391	4.23338741077223	0.00134992598697823	0.0232862232753745
GO:0005172	vascular endothelial growth factor receptor binding	3/335	13/18639	0.230769230769231	12.8397244546498	0.00143951110216395	0.0242259185486128
GO:0051393	alpha-actinin binding	4/335	28/18639	0.142857142857143	7.94840085287847	0.00149231542185829	0.0245166105019576
GO:0042562	hormone binding	7/335	94/18639	0.074468085106383	4.1433153382026	0.00152999982095047	0.0245511599175773
GO:0032266	phosphatidylinositol-3-phosphate binding	5/335	48/18639	0.104166666666667	5.79570895522388	0.00165426998796615	0.0259419611749236
GO:0003785	actin monomer binding	4/335	29/18639	0.137931034482759	7.67431806484817	0.00170682938559614	0.0261713839124741
GO:0005161	platelet-derived growth factor receptor binding	3/335	14/18639	0.214285714285714	11.9226012793177	0.00180783957381418	0.0265406235304635
GO:0044548	S100 protein binding	3/335	14/18639	0.214285714285714	11.9226012793177	0.00180783957381418	0.0265406235304635
GO:0005010	insulin-like growth factor receptor activity	5/335	51/18639	0.0980392156862745	5.45478489903424	0.00217221535161693	0.0307725677016453
GO:0004953	icosanoid receptor activity	3/335	15/18639	0.2	11.1277611940299	0.00222989621026415	0.0307725677016453
GO:0051371	muscle alpha-actinin binding	3/335	15/18639	0.2	11.1277611940299	0.00222989621026415	0.0307725677016453
GO:0035591	signaling adaptor activity	8/335	129/18639	0.062015503875969	3.45046858729608	0.00232530253643503	0.0314283083001452
GO:0030159	signaling receptor complex adaptor activity	5/335	52/18639	0.0961538461538462	5.34988518943743	0.00236851019073558	0.0314283083001452
GO:0030275	LRR domain binding	3/335	16/18639	0.1875	10.432276119403	0.00270820335699435	0.0352577418174737
GO:0002020	protease binding	8/335	136/18639	0.0588235294117647	3.27287093942054	0.00322430678891835	0.0399842059374184
GO:0030169	low-density lipoprotein particle binding	3/335	17/18639	0.176470588235294	9.81861281826163	0.00324509497463106	0.0399842059374184
GO:0046965	nuclear retinoid X receptor binding	3/335	17/18639	0.176470588235294	9.81861281826163	0.00324509497463106	0.0399842059374184
GO:0001618	virus receptor activity	6/335	81/18639	0.0740740740740741	4.12139303482587	0.0033775196400171	0.0408857640633649
GO:0004713	protein tyrosine kinase activity	8/335	140/18639	0.0571428571428571	3.17936034115139	0.00384734904251258	0.0457701868850634
GO:0005200	structural constituent of cytoskeleton	7/335	112/18639	0.0625	3.47742537313433	0.00412138010022108	0.0481991910025855
GO:0004714	transmembrane receptor protein tyrosine kinase activity	5/335	60/18639	0.0833333333333333	4.6365671641791	0.00443026524513398	0.0509480503190408
GO:0016209	antioxidant activity	6/335	86/18639	0.0697674418604651	3.88177716070809	0.00454214245894462	0.0513783327323244
GO:0001221	transcription coregulator binding	7/335	115/18639	0.0608695652173913	3.38670992861778	0.0047633218937467	0.053011163011052
GO:0031418	L-ascorbic acid binding	3/335	20/18639	0.15	8.34582089552239	0.00522794311414732	0.0572584245835183
GO:0016500	protein-hormone receptor activity	5/335	67/18639	0.0746268656716418	4.15214969926487	0.00707793707081261	0.0763090090446985
GO:0032934	sterol binding	5/335	68/18639	0.0735294117647059	4.09108867427568	0.00752991227489191	0.0799329149180834
GO:0050431	transforming growth factor beta binding	3/335	24/18639	0.125	6.95485074626866	0.00880348326154421	0.092036415916144
GO:0042974	nuclear retinoic acid receptor binding	3/335	25/18639	0.12	6.67665671641791	0.00987278843563078	0.0977974896207489
GO:0120020	cholesterol transfer activity	3/335	25/18639	0.12	6.67665671641791	0.00987278843563078	0.0977974896207489
GO:0048029	monosaccharide binding	5/335	74/18639	0.0675675675675676	3.75937878176684	0.0106700555506867	0.0977974896207489
GO:0050750	low-density lipoprotein particle receptor binding	3/335	26/18639	0.115384615384615	6.41986222732491	0.0110143460519557	0.0977974896207489
GO:0005126	cytokine receptor binding	11/335	275/18639	0.04	2.22555223880597	0.0113053206337192	0.0977974896207489
GO:0005004	GPI-linked ephrin receptor activity	4/335	49/18639	0.0816326530612245	4.54194334450198	0.0115035525212877	0.0977974896207489
GO:0005008	hepatocyte growth factor receptor activity	4/335	49/18639	0.0816326530612245	4.54194334450198	0.0115035525212877	0.0977974896207489
GO:0005009	insulin receptor activity	4/335	49/18639	0.0816326530612245	4.54194334450198	0.0115035525212877	0.0977974896207489
GO:0005011	macrophage colony-stimulating factor receptor activity	4/335	49/18639	0.0816326530612245	4.54194334450198	0.0115035525212877	0.0977974896207489
GO:0005018	platelet-derived growth factor alpha-receptor activity	4/335	49/18639	0.0816326530612245	4.54194334450198	0.0115035525212877	0.0977974896207489
GO:0005020	stem cell factor receptor activity	4/335	49/18639	0.0816326530612245	4.54194334450198	0.0115035525212877	0.0977974896207489
GO:0008288	boss receptor activity	4/335	49/18639	0.0816326530612245	4.54194334450198	0.0115035525212877	0.0977974896207489
GO:0036332	placental growth factor receptor activity	4/335	49/18639	0.0816326530612245	4.54194334450198	0.0115035525212877	0.0977974896207489
GO:0038062	protein tyrosine kinase collagen receptor activity	4/335	49/18639	0.0816326530612245	4.54194334450198	0.0115035525212877	0.0977974896207489
GO:0060175	brain-derived neurotrophic factor receptor activity	4/335	49/18639	0.0816326530612245	4.54194334450198	0.0115035525212877	0.0977974896207489
GO:0141003	histone H2AX kinase activity	13/335	354/18639	0.0367231638418079	2.04323298760435	0.0121061860045891	0.0977974896207489
GO:0008013	beta-catenin binding	6/335	106/18639	0.0566037735849057	3.14936637566883	0.0122559380285189	0.0977974896207489
GO:0005006	epidermal growth factor receptor activity	4/335	50/18639	0.08	4.45110447761194	0.0123309878217466	0.0977974896207489
GO:0005007	fibroblast growth factor receptor activity	4/335	50/18639	0.08	4.45110447761194	0.0123309878217466	0.0977974896207489
GO:0005017	platelet-derived growth factor receptor activity	4/335	50/18639	0.08	4.45110447761194	0.0123309878217466	0.0977974896207489
GO:0005019	platelet-derived growth factor beta-receptor activity	4/335	50/18639	0.08	4.45110447761194	0.0123309878217466	0.0977974896207489
GO:0140996	histone H3 kinase activity	13/335	357/18639	0.0364145658263305	2.02606296249843	0.0129103138979984	0.100054278016554
GO:0070851	growth factor receptor binding	7/335	139/18639	0.0503597122302158	2.80195425748953	0.012923049594048	0.100054278016554
GO:0005021	vascular endothelial growth factor receptor activity	4/335	51/18639	0.0784313725490196	4.36382791922739	0.0131955642021832	0.100054278016554
GO:0005030	neurotrophin receptor activity	4/335	51/18639	0.0784313725490196	4.36382791922739	0.0131955642021832	0.100054278016554
GO:0005496	steroid binding	6/335	108/18639	0.0555555555555556	3.0910447761194	0.0133482760818834	0.100112070614126
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	3/335	28/18639	0.107142857142857	5.96130063965885	0.0135173737927171	0.100290192655643
GO:0035173	histone kinase activity	13/335	360/18639	0.0361111111111111	2.00917910447761	0.0137550468814069	0.100967897320966
GO:0004629	phospholipase C activity	3/335	29/18639	0.103448275862069	5.75573854863613	0.0148801289166157	0.103289638244506
GO:0005003	ephrin receptor activity	4/335	53/18639	0.0754716981132075	4.19915516755843	0.0150382620729376	0.103289638244506
GO:0005005	transmembrane-ephrin receptor activity	4/335	53/18639	0.0754716981132075	4.19915516755843	0.0150382620729376	0.103289638244506
GO:0017046	peptide hormone binding	4/335	53/18639	0.0754716981132075	4.19915516755843	0.0150382620729376	0.103289638244506
GO:0038064	collagen receptor activity	4/335	53/18639	0.0754716981132075	4.19915516755843	0.0150382620729376	0.103289638244506
GO:0002162	dystroglycan binding	2/335	11/18639	0.181818181818182	10.1161465400271	0.0159137185379017	0.103289638244506
GO:0003953	NAD+ nucleosidase activity	2/335	11/18639	0.181818181818182	10.1161465400271	0.0159137185379017	0.103289638244506
GO:0008432	JUN kinase binding	2/335	11/18639	0.181818181818182	10.1161465400271	0.0159137185379017	0.103289638244506
GO:0043522	leucine zipper domain binding	2/335	11/18639	0.181818181818182	10.1161465400271	0.0159137185379017	0.103289638244506
GO:0048185	activin binding	2/335	11/18639	0.181818181818182	10.1161465400271	0.0159137185379017	0.103289638244506
GO:0097493	structural molecule activity conferring elasticity	2/335	11/18639	0.181818181818182	10.1161465400271	0.0159137185379017	0.103289638244506
GO:0030695	GTPase regulator activity	16/335	489/18639	0.032719836400818	1.82049262888014	0.0159669083451381	0.103289638244506
GO:0015485	cholesterol binding	4/335	54/18639	0.0740740740740741	4.12139303482587	0.016017378684293	0.103289638244506
GO:0060589	nucleoside-triphosphatase regulator activity	16/335	490/18639	0.0326530612244898	1.81677733780079	0.0162452596998865	0.103295637485115
GO:0001965	G-protein alpha-subunit binding	3/335	30/18639	0.1	5.56388059701493	0.0163177166461994	0.103295637485115
GO:0035401	histone H3Y41 kinase activity	6/335	115/18639	0.0521739130434783	2.90289422452953	0.0177060993075039	0.11006494164124
GO:0140801	histone H2AXY142 kinase activity	6/335	115/18639	0.0521739130434783	2.90289422452953	0.0177060993075039	0.11006494164124
GO:0005078	MAP-kinase scaffold activity	2/335	12/18639	0.166666666666667	9.27313432835821	0.0188720237477011	0.112696646542746
GO:0005527	macrolide binding	2/335	12/18639	0.166666666666667	9.27313432835821	0.0188720237477011	0.112696646542746
GO:0017166	vinculin binding	2/335	12/18639	0.166666666666667	9.27313432835821	0.0188720237477011	0.112696646542746
GO:0035259	nuclear glucocorticoid receptor binding	2/335	12/18639	0.166666666666667	9.27313432835821	0.0188720237477011	0.112696646542746
GO:1901981	phosphatidylinositol phosphate binding	8/335	185/18639	0.0432432432432432	2.40600242033078	0.0189461028970414	0.112696646542746
GO:0120015	sterol transfer activity	3/335	32/18639	0.09375	5.21613805970149	0.019418780466601	0.11452101300816
GO:0071889	14-3-3 protein binding	3/335	33/18639	0.0909090909090909	5.05807327001357	0.0210827078004678	0.123280240528159
GO:0001786	phosphatidylserine binding	4/335	59/18639	0.0677966101694915	3.77212243865419	0.0215081647361992	0.123671947233145
GO:0004879	nuclear receptor activity	4/335	59/18639	0.0677966101694915	3.77212243865419	0.0215081647361992	0.123671947233145
GO:0008035	high-density lipoprotein particle binding	2/335	13/18639	0.153846153846154	8.55981630309989	0.0220415715014351	0.125691606082564
GO:0098531	ligand-modulated transcription factor activity	4/335	60/18639	0.0666666666666667	3.70925373134328	0.0227280146998467	0.128543689695855
GO:0005085	guanyl-nucleotide exchange factor activity	9/335	230/18639	0.0391304347826087	2.17717066839715	0.0236564855715002	0.132707114181586
GO:0008191	metalloendopeptidase inhibitor activity	2/335	14/18639	0.142857142857143	7.94840085287847	0.0254138601560386	0.139314186448515
GO:0032036	myosin heavy chain binding	2/335	14/18639	0.142857142857143	7.94840085287847	0.0254138601560386	0.139314186448515
GO:0004674	protein serine/threonine kinase activity	14/335	433/18639	0.0323325635103926	1.79894522767226	0.0254399818732071	0.139314186448515
GO:0005507	copper ion binding	4/335	63/18639	0.0634920634920635	3.53262260127932	0.0266365950556375	0.144718508569999
GO:0005523	tropomyosin binding	2/335	15/18639	0.133333333333333	7.41850746268657	0.0289806238400039	0.156223675387521
GO:0030246	carbohydrate binding	10/335	280/18639	0.0357142857142857	1.98710021321962	0.0306057050300583	0.163704933881707
GO:0004725	protein tyrosine phosphatase activity	5/335	98/18639	0.0510204081632653	2.83871459031374	0.0318872258104011	0.168037167963904
GO:0042578	phosphoric ester hydrolase activity	12/335	363/18639	0.0330578512396694	1.83929937091402	0.0319027087003933	0.168037167963904
GO:0005024	transforming growth factor beta receptor activity	2/335	16/18639	0.125	6.95485074626866	0.0327338267661481	0.168554779616733
GO:0031435	mitogen-activated protein kinase kinase kinase binding	2/335	16/18639	0.125	6.95485074626866	0.0327338267661481	0.168554779616733
GO:0061809	NAD+ nucleosidase activity, cyclic ADP-ribose generating	2/335	16/18639	0.125	6.95485074626866	0.0327338267661481	0.168554779616733
GO:0042169	SH2 domain binding	3/335	41/18639	0.0731707317073171	4.07113214415726	0.0371111563052746	0.18967924333807
GO:0030295	protein kinase activator activity	6/335	139/18639	0.0431654676258993	2.40167507784817	0.0397828256624219	0.201839336081405
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	2/335	18/18639	0.111111111111111	6.18208955223881	0.0407685243828748	0.205330524264114
GO:0001664	G protein-coupled receptor binding	10/335	297/18639	0.0336700336700337	1.8733604703754	0.0429199737668024	0.214599868834012
GO:0001223	transcription coactivator binding	3/335	44/18639	0.0681818181818182	3.79355495251018	0.0443476406867927	0.220142964560338
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	2/335	19/18639	0.105263157894737	5.85671641791045	0.045035048501617	0.221958453329398
GO:0008194	UDP-glycosyltransferase activity	6/335	145/18639	0.0413793103448276	2.30229541945445	0.0472016468409142	0.230986782412984
GO:0017022	myosin binding	4/335	76/18639	0.0526315789473684	2.92835820895522	0.0479935938599674	0.233208308192799
GO:1902936	phosphatidylinositol bisphosphate binding	5/335	111/18639	0.045045045045045	2.50625252117789	0.0500397948291993	0.241450758266766
GO:0019209	kinase activator activity	6/335	148/18639	0.0405405405405405	2.2556272690601	0.0512116181620727	0.245389003693265
GO:0019842	vitamin binding	6/335	150/18639	0.04	2.22555223880597	0.053997312706891	0.251899387214577
GO:0001846	opsonin binding	2/335	21/18639	0.0952380952380952	5.29893390191898	0.0540305931996483	0.251899387214577
GO:0010314	phosphatidylinositol-5-phosphate binding	2/335	21/18639	0.0952380952380952	5.29893390191898	0.0540305931996483	0.251899387214577
GO:0051428	peptide hormone receptor binding	2/335	21/18639	0.0952380952380952	5.29893390191898	0.0540305931996483	0.251899387214577
GO:0001222	transcription corepressor binding	3/335	49/18639	0.0612244897959184	3.40645750837648	0.0578349447969853	0.266040746066132
GO:0035254	glutamate receptor binding	3/335	49/18639	0.0612244897959184	3.40645750837648	0.0578349447969853	0.266040746066132
GO:0015377	chloride:monoatomic cation symporter activity	2/335	22/18639	0.0909090909090909	5.05807327001357	0.05874587969529	0.266675374932566
GO:0030021	extracellular matrix structural constituent conferring compression resistance	2/335	22/18639	0.0909090909090909	5.05807327001357	0.05874587969529	0.266675374932566
GO:1990782	protein tyrosine kinase binding	5/335	117/18639	0.0427350427350427	2.37772675086108	0.0601046775368916	0.271060310460492
GO:0001540	amyloid-beta binding	4/335	83/18639	0.0481927710843374	2.68138823952527	0.0624871490834071	0.279504257806578
GO:0004602	glutathione peroxidase activity	2/335	23/18639	0.0869565217391304	4.83815704088254	0.0635973456168591	0.279504257806578
GO:0017134	fibroblast growth factor binding	2/335	23/18639	0.0869565217391304	4.83815704088254	0.0635973456168591	0.279504257806578
GO:0099186	structural constituent of postsynapse	2/335	23/18639	0.0869565217391304	4.83815704088254	0.0635973456168591	0.279504257806578
GO:0051117	ATPase binding	4/335	84/18639	0.0476190476190476	2.64946695095949	0.0647260861958876	0.282664553640269
GO:0016758	hexosyltransferase activity	7/335	197/18639	0.0355329949238579	1.97701341010683	0.0656716331827499	0.284990106264764
GO:0050699	WW domain binding	2/335	24/18639	0.0833333333333333	4.6365671641791	0.0685786058309786	0.293908310704194
GO:0060229	lipase activator activity	2/335	24/18639	0.0833333333333333	4.6365671641791	0.0685786058309786	0.293908310704194
GO:0008081	phosphoric diester hydrolase activity	4/335	87/18639	0.0459770114942529	2.55810602161606	0.0716909285627358	0.305350251285726
GO:0001848	complement binding	2/335	25/18639	0.08	4.45110447761194	0.0736834595175306	0.310009677238391
GO:0015296	monoatomic anion:monoatomic cation symporter activity	2/335	25/18639	0.08	4.45110447761194	0.0736834595175306	0.310009677238391
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	4/335	89/18639	0.0449438202247191	2.50062049304042	0.076538201804205	0.315175150399271
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	4/335	89/18639	0.0449438202247191	2.50062049304042	0.076538201804205	0.315175150399271
GO:0033218	amide binding	8/335	247/18639	0.0323886639676113	1.80206659012629	0.078470665872941	0.315175150399271
GO:0004435	phosphatidylinositol phospholipase C activity	2/335	26/18639	0.0769230769230769	4.27990815154994	0.0789058856396618	0.315175150399271
GO:0005160	transforming growth factor beta receptor binding	2/335	26/18639	0.0769230769230769	4.27990815154994	0.0789058856396618	0.315175150399271
GO:0008198	ferrous iron binding	2/335	26/18639	0.0769230769230769	4.27990815154994	0.0789058856396618	0.315175150399271
GO:0019865	immunoglobulin binding	2/335	26/18639	0.0769230769230769	4.27990815154994	0.0789058856396618	0.315175150399271
GO:0070006	metalloaminopeptidase activity	2/335	26/18639	0.0769230769230769	4.27990815154994	0.0789058856396618	0.315175150399271
GO:0140793	histone H2AXY142 phosphatase activity	4/335	90/18639	0.0444444444444444	2.47283582089552	0.0790221753899621	0.315175150399271
GO:0004679	AMP-activated protein kinase activity	8/335	248/18639	0.032258064516129	1.79480019258546	0.0798915779509168	0.31681142980536
GO:0031490	chromatin DNA binding	5/335	128/18639	0.0390625	2.17339085820896	0.081321287086916	0.317890988348009
GO:0042277	peptide binding	8/335	249/18639	0.0321285140562249	1.78759215968351	0.0813277630758768	0.317890988348009
GO:0072341	modified amino acid binding	4/335	91/18639	0.043956043956044	2.44566180088568	0.0815459491849241	0.317890988348009
GO:0004601	peroxidase activity	3/335	57/18639	0.0526315789473684	2.92835820895522	0.0828919372868061	0.321322678246608
GO:0097718	disordered domain specific binding	2/335	28/18639	0.0714285714285714	3.97420042643923	0.0896802434950484	0.340853258424219
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	3/335	59/18639	0.0508474576271186	2.82909182899064	0.0897756717379187	0.340853258424219
GO:0070888	E-box binding	3/335	59/18639	0.0508474576271186	2.82909182899064	0.0897756717379187	0.340853258424219
GO:0005179	hormone activity	5/335	132/18639	0.0378787878787879	2.10753052917232	0.0899062217872577	0.340853258424219
GO:0003713	transcription coactivator activity	8/335	256/18639	0.03125	1.73871268656716	0.0918078640615832	0.346160798920724
GO:0043236	laminin binding	2/335	29/18639	0.0689655172413793	3.83715903242409	0.0952209927230805	0.355148567453652
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	2/335	29/18639	0.0689655172413793	3.83715903242409	0.0952209927230805	0.355148567453652
GO:0004721	phosphoprotein phosphatase activity	6/335	175/18639	0.0342857142857143	1.90761620469083	0.0964346172355953	0.357507708173138
GO:0015026	coreceptor activity	3/335	61/18639	0.0491803278688525	2.73633471984341	0.0968897701860534	0.357507708173138
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	13/335	484/18639	0.0268595041322314	1.49443073886765	0.0986341871427404	0.361214798881997
GO:0044325	transmembrane transporter binding	5/335	136/18639	0.0367647058823529	2.04554433713784	0.0989414449111558	0.361214798881997
GO:0051721	protein phosphatase 2A binding	2/335	30/18639	0.0666666666666667	3.70925373134328	0.100856941014286	0.364352299999254
GO:0098918	structural constituent of synapse	2/335	30/18639	0.0666666666666667	3.70925373134328	0.100856941014286	0.364352299999254
GO:0005319	lipid transporter activity	6/335	178/18639	0.0337078651685393	1.87546536978031	0.102460501184019	0.368217426130069
GO:0070273	phosphatidylinositol-4-phosphate binding	2/335	31/18639	0.0645161290322581	3.58960038517092	0.106582901810235	0.380453378130935
GO:0001216	DNA-binding transcription activator activity	13/335	491/18639	0.0264765784114053	1.47312520898562	0.106968051242611	0.380453378130935
GO:0016757	glycosyltransferase activity	8/335	267/18639	0.0299625468164794	1.66708032869361	0.109772296588658	0.388425049467558
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	8/335	268/18639	0.0298507462686567	1.66085987970595	0.111494843759998	0.391485764501352
GO:0120013	lipid transfer activity	3/335	65/18639	0.0461538461538462	2.56794489092997	0.111772022618502	0.391485764501352
GO:0008237	metallopeptidase activity	6/335	184/18639	0.0326086956521739	1.81430889033095	0.115088249458061	0.400184339611804
GO:0005096	GTPase activator activity	8/335	271/18639	0.029520295202952	1.64247397697858	0.116750572086468	0.400184339611804
GO:0106310	protein serine kinase activity	10/335	361/18639	0.0277008310249307	1.54124116260801	0.117551246714779	0.400184339611804
GO:0019239	deaminase activity	2/335	33/18639	0.0606060606060606	3.37204884667571	0.1182848842288	0.400184339611804
GO:0030296	protein tyrosine kinase activator activity	2/335	33/18639	0.0606060606060606	3.37204884667571	0.1182848842288	0.400184339611804
GO:0019903	protein phosphatase binding	5/335	144/18639	0.0347222222222222	1.93190298507463	0.118315369972185	0.400184339611804
GO:0019955	cytokine binding	5/335	144/18639	0.0347222222222222	1.93190298507463	0.118315369972185	0.400184339611804
GO:0016791	phosphatase activity	8/335	273/18639	0.0293040293040293	1.63044120059045	0.120327263945875	0.405003961573919
GO:0031406	carboxylic acid binding	6/335	187/18639	0.0320855614973262	1.78520233059302	0.121683599868487	0.40631938696812
GO:0008376	acetylgalactosaminyltransferase activity	2/335	34/18639	0.0588235294117647	3.27287093942054	0.124251290797497	0.40631938696812
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	2/335	34/18639	0.0588235294117647	3.27287093942054	0.124251290797497	0.40631938696812
GO:0019825	oxygen binding	2/335	34/18639	0.0588235294117647	3.27287093942054	0.124251290797497	0.40631938696812
GO:0051427	hormone receptor binding	2/335	34/18639	0.0588235294117647	3.27287093942054	0.124251290797497	0.40631938696812
GO:0090482	vitamin transmembrane transporter activity	2/335	34/18639	0.0588235294117647	3.27287093942054	0.124251290797497	0.40631938696812
GO:0043177	organic acid binding	6/335	189/18639	0.0317460317460317	1.76631130063966	0.126182277939213	0.410687602726684
GO:0001217	DNA-binding transcription repressor activity	8/335	278/18639	0.0287769784172662	1.60111671856545	0.129520615857596	0.419219986787014
GO:0005154	epidermal growth factor receptor binding	2/335	35/18639	0.0571428571428571	3.17936034115139	0.130288472311085	0.419219986787014
GO:0008509	monoatomic anion transmembrane transporter activity	5/335	149/18639	0.0335570469798658	1.86707402584393	0.131266172464756	0.419219986787014
GO:0097110	scaffold protein binding	3/335	70/18639	0.0428571428571429	2.38452025586354	0.131502882368937	0.419219986787014
GO:0004222	metalloendopeptidase activity	4/335	110/18639	0.0363636363636364	2.02322930800543	0.136539871936372	0.419219986787014
GO:0035091	phosphatidylinositol binding	8/335	284/18639	0.028169014084507	1.56729030901829	0.141017583821316	0.419219986787014
GO:0019207	kinase regulator activity	8/335	287/18639	0.0278745644599303	1.55090748348848	0.146951591746218	0.419219986787014
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	7/335	243/18639	0.0288065843621399	1.60276395798784	0.149204688087848	0.419219986787014
GO:0003725	double-stranded RNA binding	3/335	75/18639	0.04	2.22555223880597	0.152345339720412	0.419219986787014
GO:0017124	SH3 domain binding	4/335	115/18639	0.0347826086956522	1.93526281635302	0.153007253251614	0.419219986787014
GO:0004676	3-phosphoinositide-dependent protein kinase activity	7/335	245/18639	0.0285714285714286	1.58968017057569	0.15364479229835	0.419219986787014
GO:0004711	ribosomal protein S6 kinase activity	7/335	245/18639	0.0285714285714286	1.58968017057569	0.15364479229835	0.419219986787014
GO:0035175	histone H3S10 kinase activity	7/335	245/18639	0.0285714285714286	1.58968017057569	0.15364479229835	0.419219986787014
GO:0035979	histone H2AXS139 kinase activity	7/335	245/18639	0.0285714285714286	1.58968017057569	0.15364479229835	0.419219986787014
GO:0044022	histone H3S28 kinase activity	7/335	245/18639	0.0285714285714286	1.58968017057569	0.15364479229835	0.419219986787014
GO:0044023	histone H4S1 kinase activity	7/335	245/18639	0.0285714285714286	1.58968017057569	0.15364479229835	0.419219986787014
GO:0044024	histone H2AS1 kinase activity	7/335	245/18639	0.0285714285714286	1.58968017057569	0.15364479229835	0.419219986787014
GO:0044025	histone H2BS14 kinase activity	7/335	245/18639	0.0285714285714286	1.58968017057569	0.15364479229835	0.419219986787014
GO:0072354	histone H3T3 kinase activity	7/335	245/18639	0.0285714285714286	1.58968017057569	0.15364479229835	0.419219986787014
GO:0072371	histone H2AS121 kinase activity	7/335	245/18639	0.0285714285714286	1.58968017057569	0.15364479229835	0.419219986787014
GO:0072518	Rho-dependent protein serine/threonine kinase activity	7/335	245/18639	0.0285714285714286	1.58968017057569	0.15364479229835	0.419219986787014
GO:0140823	histone H2BS36 kinase activity	7/335	245/18639	0.0285714285714286	1.58968017057569	0.15364479229835	0.419219986787014
GO:0140855	histone H3S57 kinase activity	7/335	245/18639	0.0285714285714286	1.58968017057569	0.15364479229835	0.419219986787014
GO:0140995	histone H2A kinase activity	7/335	245/18639	0.0285714285714286	1.58968017057569	0.15364479229835	0.419219986787014
GO:0140997	histone H4 kinase activity	7/335	245/18639	0.0285714285714286	1.58968017057569	0.15364479229835	0.419219986787014
GO:0140998	histone H2B kinase activity	7/335	245/18639	0.0285714285714286	1.58968017057569	0.15364479229835	0.419219986787014
GO:1990244	histone H2AT120 kinase activity	7/335	245/18639	0.0285714285714286	1.58968017057569	0.15364479229835	0.419219986787014
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	2/335	39/18639	0.0512820512820513	2.8532721010333	0.155057954022322	0.419219986787014
GO:0004677	DNA-dependent protein kinase activity	7/335	246/18639	0.0284552845528455	1.58321805606116	0.155887714173917	0.419219986787014
GO:0140857	histone H3T45 kinase activity	7/335	246/18639	0.0284552845528455	1.58321805606116	0.155887714173917	0.419219986787014
GO:0015294	solute:monoatomic cation symporter activity	4/335	116/18639	0.0344827586206897	1.91857951621204	0.156387768549798	0.419219986787014
GO:0035402	histone H3T11 kinase activity	7/335	247/18639	0.0283400809716599	1.57680826636051	0.158145711416029	0.419219986787014
GO:0035403	histone H3T6 kinase activity	7/335	247/18639	0.0283400809716599	1.57680826636051	0.158145711416029	0.419219986787014
GO:0004177	aminopeptidase activity	2/335	40/18639	0.05	2.78194029850746	0.161384921499745	0.419219986787014
GO:0030331	nuclear estrogen receptor binding	2/335	40/18639	0.05	2.78194029850746	0.161384921499745	0.419219986787014
GO:0071855	neuropeptide receptor binding	2/335	40/18639	0.05	2.78194029850746	0.161384921499745	0.419219986787014
GO:0071949	FAD binding	2/335	40/18639	0.05	2.78194029850746	0.161384921499745	0.419219986787014
GO:0003714	transcription corepressor activity	6/335	204/18639	0.0294117647058824	1.63643546971027	0.162382755546714	0.419219986787014
GO:0004862	cAMP-dependent protein kinase inhibitor activity	1/335	10/18639	0.1	5.56388059701493	0.165906395315645	0.419219986787014
GO:0005131	growth hormone receptor binding	1/335	10/18639	0.1	5.56388059701493	0.165906395315645	0.419219986787014
GO:0005528	FK506 binding	1/335	10/18639	0.1	5.56388059701493	0.165906395315645	0.419219986787014
GO:0015187	glycine transmembrane transporter activity	1/335	10/18639	0.1	5.56388059701493	0.165906395315645	0.419219986787014
GO:0015643	toxic substance binding	1/335	10/18639	0.1	5.56388059701493	0.165906395315645	0.419219986787014
GO:0016303	1-phosphatidylinositol-3-kinase activity	1/335	10/18639	0.1	5.56388059701493	0.165906395315645	0.419219986787014
GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines	1/335	10/18639	0.1	5.56388059701493	0.165906395315645	0.419219986787014
GO:0031434	mitogen-activated protein kinase kinase binding	1/335	10/18639	0.1	5.56388059701493	0.165906395315645	0.419219986787014
GO:0031720	haptoglobin binding	1/335	10/18639	0.1	5.56388059701493	0.165906395315645	0.419219986787014
GO:0035256	G protein-coupled glutamate receptor binding	1/335	10/18639	0.1	5.56388059701493	0.165906395315645	0.419219986787014
GO:0035374	chondroitin sulfate binding	1/335	10/18639	0.1	5.56388059701493	0.165906395315645	0.419219986787014
GO:0042975	peroxisome proliferator activated receptor binding	1/335	10/18639	0.1	5.56388059701493	0.165906395315645	0.419219986787014
GO:0043121	neurotrophin binding	1/335	10/18639	0.1	5.56388059701493	0.165906395315645	0.419219986787014
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	2/335	41/18639	0.0487804878048781	2.71408809610484	0.167757935099461	0.419219986787014
GO:0015370	solute:sodium symporter activity	3/335	79/18639	0.0379746835443038	2.11286604949934	0.169716992267537	0.419219986787014
GO:0046332	SMAD binding	3/335	79/18639	0.0379746835443038	2.11286604949934	0.169716992267537	0.419219986787014
GO:0005516	calmodulin binding	6/335	207/18639	0.0289855072463768	1.61271901362751	0.170111923655611	0.419219986787014
GO:0015108	chloride transmembrane transporter activity	4/335	121/18639	0.0330578512396694	1.83929937091402	0.173695224849196	0.419219986787014
GO:0048306	calcium-dependent protein binding	3/335	80/18639	0.0375	2.0864552238806	0.174146684710247	0.419219986787014
GO:0035198	miRNA binding	2/335	42/18639	0.0476190476190476	2.64946695095949	0.174173311523474	0.419219986787014
GO:0042056	chemoattractant activity	2/335	42/18639	0.0476190476190476	2.64946695095949	0.174173311523474	0.419219986787014
GO:0015103	inorganic anion transmembrane transporter activity	5/335	165/18639	0.0303030303030303	1.68602442333786	0.176631700905384	0.419219986787014
GO:0019887	protein kinase regulator activity	7/335	255/18639	0.0274509803921569	1.52733977172959	0.176736267542252	0.419219986787014
GO:0015101	organic cation transmembrane transporter activity	3/335	81/18639	0.037037037037037	2.06069651741294	0.178608684854114	0.419219986787014
GO:0030971	receptor tyrosine kinase binding	3/335	81/18639	0.037037037037037	2.06069651741294	0.178608684854114	0.419219986787014
GO:0008200	ion channel inhibitor activity	2/335	43/18639	0.0465116279069767	2.58785144047206	0.180627484266184	0.419219986787014
GO:0008375	acetylglucosaminyltransferase activity	2/335	43/18639	0.0465116279069767	2.58785144047206	0.180627484266184	0.419219986787014
GO:0001161	intronic transcription regulatory region sequence-specific DNA binding	1/335	11/18639	0.0909090909090909	5.05807327001357	0.18090566299342	0.419219986787014
GO:0001851	complement component C3b binding	1/335	11/18639	0.0909090909090909	5.05807327001357	0.18090566299342	0.419219986787014
GO:0005114	type II transforming growth factor beta receptor binding	1/335	11/18639	0.0909090909090909	5.05807327001357	0.18090566299342	0.419219986787014
GO:0005536	D-glucose binding	1/335	11/18639	0.0909090909090909	5.05807327001357	0.18090566299342	0.419219986787014
GO:0008199	ferric iron binding	1/335	11/18639	0.0909090909090909	5.05807327001357	0.18090566299342	0.419219986787014
GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity	1/335	11/18639	0.0909090909090909	5.05807327001357	0.18090566299342	0.419219986787014
GO:0015173	aromatic amino acid transmembrane transporter activity	1/335	11/18639	0.0909090909090909	5.05807327001357	0.18090566299342	0.419219986787014
GO:0016176	superoxide-generating NADPH oxidase activator activity	1/335	11/18639	0.0909090909090909	5.05807327001357	0.18090566299342	0.419219986787014
GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor	1/335	11/18639	0.0909090909090909	5.05807327001357	0.18090566299342	0.419219986787014
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	1/335	11/18639	0.0909090909090909	5.05807327001357	0.18090566299342	0.419219986787014
GO:0019206	nucleoside kinase activity	1/335	11/18639	0.0909090909090909	5.05807327001357	0.18090566299342	0.419219986787014
GO:0032050	clathrin heavy chain binding	1/335	11/18639	0.0909090909090909	5.05807327001357	0.18090566299342	0.419219986787014
GO:0034713	type I transforming growth factor beta receptor binding	1/335	11/18639	0.0909090909090909	5.05807327001357	0.18090566299342	0.419219986787014
GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	1/335	11/18639	0.0909090909090909	5.05807327001357	0.18090566299342	0.419219986787014
GO:0045294	alpha-catenin binding	1/335	11/18639	0.0909090909090909	5.05807327001357	0.18090566299342	0.419219986787014
GO:0050998	nitric-oxide synthase binding	1/335	11/18639	0.0909090909090909	5.05807327001357	0.18090566299342	0.419219986787014
GO:0070697	activin receptor binding	1/335	11/18639	0.0909090909090909	5.05807327001357	0.18090566299342	0.419219986787014
GO:0016248	channel inhibitor activity	2/335	44/18639	0.0454545454545455	2.52903663500678	0.187117000627107	0.419219986787014
GO:0019205	nucleobase-containing compound kinase activity	2/335	44/18639	0.0454545454545455	2.52903663500678	0.187117000627107	0.419219986787014
GO:0030165	PDZ domain binding	3/335	83/18639	0.036144578313253	2.01104117964395	0.187624851068912	0.419219986787014
GO:0004715	non-membrane spanning protein tyrosine kinase activity	2/335	45/18639	0.0444444444444444	2.47283582089552	0.193638518792731	0.419219986787014
GO:0008009	chemokine activity	2/335	45/18639	0.0444444444444444	2.47283582089552	0.193638518792731	0.419219986787014
GO:0042605	peptide antigen binding	2/335	45/18639	0.0444444444444444	2.47283582089552	0.193638518792731	0.419219986787014
GO:0141110	transporter inhibitor activity	2/335	45/18639	0.0444444444444444	2.47283582089552	0.193638518792731	0.419219986787014
GO:0004000	adenosine deaminase activity	1/335	12/18639	0.0833333333333333	4.6365671641791	0.19563599383394	0.419219986787014
GO:0004126	cytidine deaminase activity	1/335	12/18639	0.0833333333333333	4.6365671641791	0.19563599383394	0.419219986787014
GO:0004859	phospholipase inhibitor activity	1/335	12/18639	0.0833333333333333	4.6365671641791	0.19563599383394	0.419219986787014
GO:0008504	monoamine transmembrane transporter activity	1/335	12/18639	0.0833333333333333	4.6365671641791	0.19563599383394	0.419219986787014
GO:0008603	cAMP-dependent protein kinase regulator activity	1/335	12/18639	0.0833333333333333	4.6365671641791	0.19563599383394	0.419219986787014
GO:0015132	prostaglandin transmembrane transporter activity	1/335	12/18639	0.0833333333333333	4.6365671641791	0.19563599383394	0.419219986787014
GO:0015269	calcium-activated potassium channel activity	1/335	12/18639	0.0833333333333333	4.6365671641791	0.19563599383394	0.419219986787014
GO:0016208	AMP binding	1/335	12/18639	0.0833333333333333	4.6365671641791	0.19563599383394	0.419219986787014
GO:0016840	carbon-nitrogen lyase activity	1/335	12/18639	0.0833333333333333	4.6365671641791	0.19563599383394	0.419219986787014
GO:0031543	peptidyl-proline dioxygenase activity	1/335	12/18639	0.0833333333333333	4.6365671641791	0.19563599383394	0.419219986787014
GO:0035014	phosphatidylinositol 3-kinase regulator activity	1/335	12/18639	0.0833333333333333	4.6365671641791	0.19563599383394	0.419219986787014
GO:0035497	cAMP response element binding	1/335	12/18639	0.0833333333333333	4.6365671641791	0.19563599383394	0.419219986787014
GO:0045295	gamma-catenin binding	1/335	12/18639	0.0833333333333333	4.6365671641791	0.19563599383394	0.419219986787014
GO:0070679	inositol 1,4,5 trisphosphate binding	1/335	12/18639	0.0833333333333333	4.6365671641791	0.19563599383394	0.419219986787014
GO:0097677	STAT family protein binding	1/335	12/18639	0.0833333333333333	4.6365671641791	0.19563599383394	0.419219986787014
GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	1/335	12/18639	0.0833333333333333	4.6365671641791	0.19563599383394	0.419219986787014
GO:0140822	NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity	1/335	12/18639	0.0833333333333333	4.6365671641791	0.19563599383394	0.419219986787014
GO:0140844	NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity	1/335	12/18639	0.0833333333333333	4.6365671641791	0.19563599383394	0.419219986787014
GO:0140867	NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity	1/335	12/18639	0.0833333333333333	4.6365671641791	0.19563599383394	0.419219986787014
GO:1990247	N6-methyladenosine-containing RNA reader activity	1/335	12/18639	0.0833333333333333	4.6365671641791	0.19563599383394	0.419219986787014
GO:1990459	transferrin receptor binding	1/335	12/18639	0.0833333333333333	4.6365671641791	0.19563599383394	0.419219986787014
GO:0030276	clathrin binding	2/335	46/18639	0.0434782608695652	2.41907852044127	0.200188804985992	0.425145177174442
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	3/335	86/18639	0.0348837209302326	1.94088858035404	0.201361877106942	0.425145177174442
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	4/335	130/18639	0.0307692307692308	1.71196326061998	0.20637086099849	0.425145177174442
GO:0001784	phosphotyrosine residue binding	2/335	47/18639	0.0425531914893617	2.3676087646872	0.206764730681914	0.425145177174442
GO:0005504	fatty acid binding	2/335	47/18639	0.0425531914893617	2.3676087646872	0.206764730681914	0.425145177174442
GO:0005338	nucleotide-sugar transmembrane transporter activity	1/335	13/18639	0.0769230769230769	4.27990815154994	0.210102195694982	0.425145177174442
GO:0008253	5'-nucleotidase activity	1/335	13/18639	0.0769230769230769	4.27990815154994	0.210102195694982	0.425145177174442
GO:0019855	calcium channel inhibitor activity	1/335	13/18639	0.0769230769230769	4.27990815154994	0.210102195694982	0.425145177174442
GO:0039706	co-receptor binding	1/335	13/18639	0.0769230769230769	4.27990815154994	0.210102195694982	0.425145177174442
GO:0045159	myosin II binding	1/335	13/18639	0.0769230769230769	4.27990815154994	0.210102195694982	0.425145177174442
GO:0061459	L-arginine transmembrane transporter activity	1/335	13/18639	0.0769230769230769	4.27990815154994	0.210102195694982	0.425145177174442
GO:0070123	transforming growth factor beta receptor activity, type III	1/335	13/18639	0.0769230769230769	4.27990815154994	0.210102195694982	0.425145177174442
GO:0071714	icosanoid transmembrane transporter activity	1/335	13/18639	0.0769230769230769	4.27990815154994	0.210102195694982	0.425145177174442
GO:0071837	HMG box domain binding	1/335	13/18639	0.0769230769230769	4.27990815154994	0.210102195694982	0.425145177174442
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	1/335	13/18639	0.0769230769230769	4.27990815154994	0.210102195694982	0.425145177174442
GO:0097157	pre-mRNA intronic binding	1/335	13/18639	0.0769230769230769	4.27990815154994	0.210102195694982	0.425145177174442
GO:0140410	monoatomic cation:bicarbonate symporter activity	1/335	13/18639	0.0769230769230769	4.27990815154994	0.210102195694982	0.425145177174442
GO:0140806	NAD+-protein-aspartate ADP-ribosyltransferase activity	1/335	13/18639	0.0769230769230769	4.27990815154994	0.210102195694982	0.425145177174442
GO:0031072	heat shock protein binding	4/335	131/18639	0.0305343511450382	1.69889483878318	0.21010797886447	0.425145177174442
GO:0051087	protein-folding chaperone binding	4/335	134/18639	0.0298507462686567	1.66085987970595	0.221432153579466	0.439696601159497
GO:0004065	arylsulfatase activity	1/335	14/18639	0.0714285714285714	3.97420042643923	0.224308990736439	0.439696601159497
GO:0005344	oxygen carrier activity	1/335	14/18639	0.0714285714285714	3.97420042643923	0.224308990736439	0.439696601159497
GO:0005545	1-phosphatidylinositol binding	1/335	14/18639	0.0714285714285714	3.97420042643923	0.224308990736439	0.439696601159497
GO:0008331	high voltage-gated calcium channel activity	1/335	14/18639	0.0714285714285714	3.97420042643923	0.224308990736439	0.439696601159497
GO:0008494	translation activator activity	1/335	14/18639	0.0714285714285714	3.97420042643923	0.224308990736439	0.439696601159497
GO:0016530	metallochaperone activity	1/335	14/18639	0.0714285714285714	3.97420042643923	0.224308990736439	0.439696601159497
GO:0034236	protein kinase A catalytic subunit binding	1/335	14/18639	0.0714285714285714	3.97420042643923	0.224308990736439	0.439696601159497
GO:0043176	amine binding	1/335	14/18639	0.0714285714285714	3.97420042643923	0.224308990736439	0.439696601159497
GO:0052816	long-chain fatty acyl-CoA hydrolase activity	1/335	14/18639	0.0714285714285714	3.97420042643923	0.224308990736439	0.439696601159497
GO:1901474	azole transmembrane transporter activity	1/335	14/18639	0.0714285714285714	3.97420042643923	0.224308990736439	0.439696601159497
GO:0032813	tumor necrosis factor receptor superfamily binding	2/335	50/18639	0.04	2.22555223880597	0.226616581645824	0.44171028625881
GO:0048020	CCR chemokine receptor binding	2/335	50/18639	0.04	2.22555223880597	0.226616581645824	0.44171028625881
GO:0140789	histone phosphatase activity	4/335	136/18639	0.0294117647058824	1.63643546971027	0.229069876776349	0.4452344083822
GO:0016922	nuclear receptor binding	4/335	137/18639	0.0291970802919708	1.62449068525983	0.232913502807087	0.447956680356664
GO:0051219	phosphoprotein binding	3/335	93/18639	0.032258064516129	1.79480019258546	0.234247407066854	0.447956680356664
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	1/335	15/18639	0.0666666666666667	3.70925373134328	0.238261016943327	0.447956680356664
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	1/335	15/18639	0.0666666666666667	3.70925373134328	0.238261016943327	0.447956680356664
GO:0005041	low-density lipoprotein particle receptor activity	1/335	15/18639	0.0666666666666667	3.70925373134328	0.238261016943327	0.447956680356664
GO:0008252	nucleotidase activity	1/335	15/18639	0.0666666666666667	3.70925373134328	0.238261016943327	0.447956680356664
GO:0015929	hexosaminidase activity	1/335	15/18639	0.0666666666666667	3.70925373134328	0.238261016943327	0.447956680356664
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	1/335	15/18639	0.0666666666666667	3.70925373134328	0.238261016943327	0.447956680356664
GO:0030553	cGMP binding	1/335	15/18639	0.0666666666666667	3.70925373134328	0.238261016943327	0.447956680356664
GO:0033130	acetylcholine receptor binding	1/335	15/18639	0.0666666666666667	3.70925373134328	0.238261016943327	0.447956680356664
GO:0120283	protein serine/threonine kinase binding	1/335	15/18639	0.0666666666666667	3.70925373134328	0.238261016943327	0.447956680356664
GO:0140776	protein-containing complex destabilizing activity	1/335	15/18639	0.0666666666666667	3.70925373134328	0.238261016943327	0.447956680356664
GO:0005080	protein kinase C binding	2/335	52/18639	0.0384615384615385	2.13995407577497	0.239926483562163	0.449862156679055
GO:0005125	cytokine activity	6/335	234/18639	0.0256410256410256	1.42663605051665	0.245751498972646	0.456286723449888
GO:0016860	intramolecular oxidoreductase activity	2/335	53/18639	0.0377358490566038	2.09957758377922	0.246596106547726	0.456286723449888
GO:0051018	protein kinase A binding	2/335	53/18639	0.0377358490566038	2.09957758377922	0.246596106547726	0.456286723449888
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	1/335	16/18639	0.0625	3.47742537313433	0.251962829621805	0.456286723449888
GO:0005159	insulin-like growth factor receptor binding	1/335	16/18639	0.0625	3.47742537313433	0.251962829621805	0.456286723449888
GO:0008142	oxysterol binding	1/335	16/18639	0.0625	3.47742537313433	0.251962829621805	0.456286723449888
GO:0015378	sodium:chloride symporter activity	1/335	16/18639	0.0625	3.47742537313433	0.251962829621805	0.456286723449888
GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	1/335	16/18639	0.0625	3.47742537313433	0.251962829621805	0.456286723449888
GO:0016722	oxidoreductase activity, acting on metal ions	1/335	16/18639	0.0625	3.47742537313433	0.251962829621805	0.456286723449888
GO:0019841	retinol binding	1/335	16/18639	0.0625	3.47742537313433	0.251962829621805	0.456286723449888
GO:0022858	alanine transmembrane transporter activity	1/335	16/18639	0.0625	3.47742537313433	0.251962829621805	0.456286723449888
GO:0034450	ubiquitin-ubiquitin ligase activity	1/335	16/18639	0.0625	3.47742537313433	0.251962829621805	0.456286723449888
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	2/335	54/18639	0.037037037037037	2.06069651741294	0.25327219577001	0.456286723449888
GO:0051287	NAD binding	2/335	54/18639	0.037037037037037	2.06069651741294	0.25327219577001	0.456286723449888
GO:0140463	chromatin-protein adaptor activity	2/335	54/18639	0.037037037037037	2.06069651741294	0.25327219577001	0.456286723449888
GO:0019902	phosphatase binding	5/335	190/18639	0.0263157894736842	1.46417910447761	0.257006046356625	0.461307413046335
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	1/335	17/18639	0.0588235294117647	3.27287093942054	0.265418902868688	0.461307413046335
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	1/335	17/18639	0.0588235294117647	3.27287093942054	0.265418902868688	0.461307413046335
GO:0008484	sulfuric ester hydrolase activity	1/335	17/18639	0.0588235294117647	3.27287093942054	0.265418902868688	0.461307413046335
GO:0015347	sodium-independent organic anion transmembrane transporter activity	1/335	17/18639	0.0588235294117647	3.27287093942054	0.265418902868688	0.461307413046335
GO:0019198	transmembrane receptor protein phosphatase activity	1/335	17/18639	0.0588235294117647	3.27287093942054	0.265418902868688	0.461307413046335
GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	1/335	17/18639	0.0588235294117647	3.27287093942054	0.265418902868688	0.461307413046335
GO:0036041	long-chain fatty acid binding	1/335	17/18639	0.0588235294117647	3.27287093942054	0.265418902868688	0.461307413046335
GO:0038191	neuropilin binding	1/335	17/18639	0.0588235294117647	3.27287093942054	0.265418902868688	0.461307413046335
GO:0045125	bioactive lipid receptor activity	1/335	17/18639	0.0588235294117647	3.27287093942054	0.265418902868688	0.461307413046335
GO:0048038	quinone binding	1/335	17/18639	0.0588235294117647	3.27287093942054	0.265418902868688	0.461307413046335
GO:0051787	misfolded protein binding	1/335	17/18639	0.0588235294117647	3.27287093942054	0.265418902868688	0.461307413046335
GO:0070403	NAD+ binding	1/335	17/18639	0.0588235294117647	3.27287093942054	0.265418902868688	0.461307413046335
GO:1990226	histone methyltransferase binding	1/335	17/18639	0.0588235294117647	3.27287093942054	0.265418902868688	0.461307413046335
GO:0170055	lipid transmembrane transporter activity	2/335	56/18639	0.0357142857142857	1.98710021321962	0.266634338781995	0.462255511958735
GO:0015293	symporter activity	4/335	146/18639	0.0273972602739726	1.52435084849724	0.268147186085224	0.463713178944372
GO:0008236	serine-type peptidase activity	5/335	194/18639	0.0257731958762887	1.43398984459148	0.270642901985473	0.466859005924941
GO:0000400	four-way junction DNA binding	1/335	18/18639	0.0555555555555556	3.0910447761194	0.278633631014912	0.470436049248007
GO:0015373	monoatomic anion:sodium symporter activity	1/335	18/18639	0.0555555555555556	3.0910447761194	0.278633631014912	0.470436049248007
GO:0017075	syntaxin-1 binding	1/335	18/18639	0.0555555555555556	3.0910447761194	0.278633631014912	0.470436049248007
GO:0030228	lipoprotein particle receptor activity	1/335	18/18639	0.0555555555555556	3.0910447761194	0.278633631014912	0.470436049248007
GO:0035615	clathrin adaptor activity	1/335	18/18639	0.0555555555555556	3.0910447761194	0.278633631014912	0.470436049248007
GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	1/335	18/18639	0.0555555555555556	3.0910447761194	0.278633631014912	0.470436049248007
GO:0050811	GABA receptor binding	1/335	18/18639	0.0555555555555556	3.0910447761194	0.278633631014912	0.470436049248007
GO:0070064	proline-rich region binding	1/335	18/18639	0.0555555555555556	3.0910447761194	0.278633631014912	0.470436049248007
GO:0003712	transcription coregulator activity	11/335	495/18639	0.0222222222222222	1.23641791044776	0.278852672670195	0.470436049248007
GO:0061980	regulatory RNA binding	2/335	58/18639	0.0344827586206897	1.91857951621204	0.279994860586198	0.471210862937747
GO:0017171	serine hydrolase activity	5/335	198/18639	0.0252525252525253	1.40502035278155	0.284432362222878	0.477514184753737
GO:0015459	potassium channel regulator activity	2/335	59/18639	0.0338983050847458	1.88606121932709	0.286669218089646	0.477937809334836
GO:0045309	protein phosphorylated amino acid binding	2/335	59/18639	0.0338983050847458	1.88606121932709	0.286669218089646	0.477937809334836
GO:0003756	protein disulfide isomerase activity	1/335	19/18639	0.0526315789473684	2.92835820895522	0.291611330043429	0.477937809334836
GO:0008301	DNA binding, bending	1/335	19/18639	0.0526315789473684	2.92835820895522	0.291611330043429	0.477937809334836
GO:0008574	plus-end-directed microtubule motor activity	1/335	19/18639	0.0526315789473684	2.92835820895522	0.291611330043429	0.477937809334836
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	1/335	19/18639	0.0526315789473684	2.92835820895522	0.291611330043429	0.477937809334836
GO:0016918	retinal binding	1/335	19/18639	0.0526315789473684	2.92835820895522	0.291611330043429	0.477937809334836
GO:0042577	lipid phosphatase activity	1/335	19/18639	0.0526315789473684	2.92835820895522	0.291611330043429	0.477937809334836
GO:0043395	heparan sulfate proteoglycan binding	1/335	19/18639	0.0526315789473684	2.92835820895522	0.291611330043429	0.477937809334836
GO:0050145	nucleoside monophosphate kinase activity	1/335	19/18639	0.0526315789473684	2.92835820895522	0.291611330043429	0.477937809334836
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	2/335	60/18639	0.0333333333333333	1.85462686567164	0.293336967134374	0.479626794603596
GO:0005506	iron ion binding	4/335	154/18639	0.025974025974026	1.44516379143245	0.300209011407406	0.4897026427213
GO:0005326	neurotransmitter transmembrane transporter activity	1/335	20/18639	0.05	2.78194029850746	0.30435623898196	0.49297137299895
GO:0016004	phospholipase activator activity	1/335	20/18639	0.05	2.78194029850746	0.30435623898196	0.49297137299895
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	1/335	20/18639	0.05	2.78194029850746	0.30435623898196	0.49297137299895
GO:0004175	endopeptidase activity	9/335	405/18639	0.0222222222222222	1.23641791044776	0.305949778964192	0.494357683858348
GO:0015179	L-amino acid transmembrane transporter activity	2/335	62/18639	0.032258064516129	1.79480019258546	0.306645056074454	0.494357683858348
GO:0004620	phospholipase activity	3/335	109/18639	0.0275229357798165	1.53134328358209	0.312088604545223	0.50147256806661
GO:0005123	death receptor binding	1/335	21/18639	0.0476190476190476	2.64946695095949	0.316872521271076	0.50147256806661
GO:0009931	calcium-dependent protein serine/threonine kinase activity	1/335	21/18639	0.0476190476190476	2.64946695095949	0.316872521271076	0.50147256806661
GO:0015174	basic amino acid transmembrane transporter activity	1/335	21/18639	0.0476190476190476	2.64946695095949	0.316872521271076	0.50147256806661
GO:0036122	BMP binding	1/335	21/18639	0.0476190476190476	2.64946695095949	0.316872521271076	0.50147256806661
GO:0051010	microtubule plus-end binding	1/335	21/18639	0.0476190476190476	2.64946695095949	0.316872521271076	0.50147256806661
GO:0061891	calcium ion sensor activity	1/335	21/18639	0.0476190476190476	2.64946695095949	0.316872521271076	0.50147256806661
GO:0140312	cargo adaptor activity	1/335	21/18639	0.0476190476190476	2.64946695095949	0.316872521271076	0.50147256806661
GO:0038024	cargo receptor activity	2/335	65/18639	0.0307692307692308	1.71196326061998	0.326512038695531	0.515018919760844
GO:0005243	gap junction channel activity	1/335	22/18639	0.0454545454545455	2.52903663500678	0.329164266108018	0.515018919760844
GO:0050321	tau-protein kinase activity	1/335	22/18639	0.0454545454545455	2.52903663500678	0.329164266108018	0.515018919760844
GO:0140517	protein-RNA adaptor activity	1/335	22/18639	0.0454545454545455	2.52903663500678	0.329164266108018	0.515018919760844
GO:0140784	metal ion sensor activity	1/335	22/18639	0.0454545454545455	2.52903663500678	0.329164266108018	0.515018919760844
GO:0008083	growth factor activity	4/335	162/18639	0.0246913580246914	1.37379767827529	0.332686952413835	0.518827594545124
GO:0008235	metalloexopeptidase activity	2/335	66/18639	0.0303030303030303	1.68602442333786	0.333102354178971	0.518827594545124
GO:0051020	GTPase binding	7/335	315/18639	0.0222222222222222	1.23641791044776	0.338518235761969	0.523227750975618
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	1/335	23/18639	0.0434782608695652	2.41907852044127	0.341235489766707	0.523227750975618
GO:0005212	structural constituent of eye lens	1/335	23/18639	0.0434782608695652	2.41907852044127	0.341235489766707	0.523227750975618
GO:0005283	amino acid:sodium symporter activity	1/335	23/18639	0.0434782608695652	2.41907852044127	0.341235489766707	0.523227750975618
GO:0043274	phospholipase binding	1/335	23/18639	0.0434782608695652	2.41907852044127	0.341235489766707	0.523227750975618
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	1/335	23/18639	0.0434782608695652	2.41907852044127	0.341235489766707	0.523227750975618
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	1/335	23/18639	0.0434782608695652	2.41907852044127	0.341235489766707	0.523227750975618
GO:1990841	promoter-specific chromatin binding	2/335	68/18639	0.0294117647058824	1.63643546971027	0.346225763336742	0.529702387366634
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	1/335	24/18639	0.0416666666666667	2.31828358208955	0.353090136894347	0.531948022832095
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	1/335	24/18639	0.0416666666666667	2.31828358208955	0.353090136894347	0.531948022832095
GO:0005540	hyaluronic acid binding	1/335	24/18639	0.0416666666666667	2.31828358208955	0.353090136894347	0.531948022832095
GO:0030552	cAMP binding	1/335	24/18639	0.0416666666666667	2.31828358208955	0.353090136894347	0.531948022832095
GO:0048027	mRNA 5'-UTR binding	1/335	24/18639	0.0416666666666667	2.31828358208955	0.353090136894347	0.531948022832095
GO:0070300	phosphatidic acid binding	1/335	24/18639	0.0416666666666667	2.31828358208955	0.353090136894347	0.531948022832095
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	1/335	24/18639	0.0416666666666667	2.31828358208955	0.353090136894347	0.531948022832095
GO:0000030	mannosyltransferase activity	1/335	25/18639	0.04	2.22555223880597	0.364732081785048	0.545911358853977
GO:0004709	MAP kinase kinase kinase activity	1/335	25/18639	0.04	2.22555223880597	0.364732081785048	0.545911358853977
GO:0047617	fatty acyl-CoA hydrolase activity	1/335	25/18639	0.04	2.22555223880597	0.364732081785048	0.545911358853977
GO:0042379	chemokine receptor binding	2/335	72/18639	0.0277777777777778	1.5455223880597	0.372204858810906	0.553419913529416
GO:0004112	cyclic-nucleotide phosphodiesterase activity	1/335	26/18639	0.0384615384615385	2.13995407577497	0.376165129630864	0.553419913529416
GO:0005227	calcium-activated cation channel activity	1/335	26/18639	0.0384615384615385	2.13995407577497	0.376165129630864	0.553419913529416
GO:0016289	acyl-CoA hydrolase activity	1/335	26/18639	0.0384615384615385	2.13995407577497	0.376165129630864	0.553419913529416
GO:0030247	polysaccharide binding	1/335	26/18639	0.0384615384615385	2.13995407577497	0.376165129630864	0.553419913529416
GO:0034237	protein kinase A regulatory subunit binding	1/335	26/18639	0.0384615384615385	2.13995407577497	0.376165129630864	0.553419913529416
GO:0052742	phosphatidylinositol kinase activity	1/335	26/18639	0.0384615384615385	2.13995407577497	0.376165129630864	0.553419913529416
GO:0070412	R-SMAD binding	1/335	26/18639	0.0384615384615385	2.13995407577497	0.376165129630864	0.553419913529416
GO:0008017	microtubule binding	6/335	276/18639	0.0217391304347826	1.20953926022064	0.376973276709815	0.553428853042069
GO:0043539	protein serine/threonine kinase activator activity	2/335	73/18639	0.0273972602739726	1.52435084849724	0.378636411099232	0.554690283775945
GO:0140297	DNA-binding transcription factor binding	10/335	488/18639	0.0204918032786885	1.14013946660142	0.381707648942811	0.558004825785041
GO:0004683	calcium/calmodulin-dependent protein kinase activity	1/335	27/18639	0.037037037037037	2.06069651741294	0.387393017750654	0.560379836997802
GO:0008266	poly(U) RNA binding	1/335	27/18639	0.037037037037037	2.06069651741294	0.387393017750654	0.560379836997802
GO:0015252	proton channel activity	1/335	27/18639	0.037037037037037	2.06069651741294	0.387393017750654	0.560379836997802
GO:0023026	MHC class II protein complex binding	1/335	27/18639	0.037037037037037	2.06069651741294	0.387393017750654	0.560379836997802
GO:0035255	ionotropic glutamate receptor binding	1/335	27/18639	0.037037037037037	2.06069651741294	0.387393017750654	0.560379836997802
GO:0004252	serine-type endopeptidase activity	4/335	176/18639	0.0227272727272727	1.26451831750339	0.389772433020098	0.562642215029011
GO:0044183	protein folding chaperone	2/335	75/18639	0.0266666666666667	1.48370149253731	0.391415537197062	0.563834489908085
GO:0045499	chemorepellent activity	1/335	28/18639	0.0357142857142857	1.98710021321962	0.398419416797158	0.569170595424512
GO:0046966	nuclear thyroid hormone receptor binding	1/335	28/18639	0.0357142857142857	1.98710021321962	0.398419416797158	0.569170595424512
GO:0051537	2 iron, 2 sulfur cluster binding	1/335	28/18639	0.0357142857142857	1.98710021321962	0.398419416797158	0.569170595424512
GO:0051959	dynein light intermediate chain binding	1/335	28/18639	0.0357142857142857	1.98710021321962	0.398419416797158	0.569170595424512
GO:0031267	small GTPase binding	6/335	283/18639	0.0212014134275618	1.17962132798903	0.39941505268718	0.569414021392881
GO:0042826	histone deacetylase binding	3/335	127/18639	0.0236220472440945	1.31430250323187	0.400256189202594	0.569436640308845
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	1/335	29/18639	0.0344827586206897	1.91857951621204	0.409247931942661	0.57741340016113
GO:0005416	amino acid:monoatomic cation symporter activity	1/335	29/18639	0.0344827586206897	1.91857951621204	0.409247931942661	0.57741340016113
GO:0035250	UDP-galactosyltransferase activity	1/335	29/18639	0.0344827586206897	1.91857951621204	0.409247931942661	0.57741340016113
GO:0097472	cyclin-dependent protein kinase activity	1/335	29/18639	0.0344827586206897	1.91857951621204	0.409247931942661	0.57741340016113
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	4/335	181/18639	0.0220994475138122	1.22958687226849	0.410047197215875	0.57741340016113
GO:0015291	secondary active transmembrane transporter activity	6/335	287/18639	0.0209059233449477	1.16318061261636	0.412225239009274	0.579298197385741
GO:0016298	lipase activity	3/335	130/18639	0.0230769230769231	1.28397244546498	0.414715182026896	0.5804330133845
GO:0016798	hydrolase activity, acting on glycosyl bonds	3/335	130/18639	0.0230769230769231	1.28397244546498	0.414715182026896	0.5804330133845
GO:0033293	monocarboxylic acid binding	2/335	79/18639	0.0253164556962025	1.40857736633289	0.416609159645017	0.580598500581385
GO:0008187	poly-pyrimidine tract binding	1/335	30/18639	0.0333333333333333	1.85462686567164	0.419882104043639	0.580598500581385
GO:0022839	monoatomic ion-gated channel activity	1/335	30/18639	0.0333333333333333	1.85462686567164	0.419882104043639	0.580598500581385
GO:0031210	phosphatidylcholine binding	1/335	30/18639	0.0333333333333333	1.85462686567164	0.419882104043639	0.580598500581385
GO:0033612	receptor serine/threonine kinase binding	1/335	30/18639	0.0333333333333333	1.85462686567164	0.419882104043639	0.580598500581385
GO:0048019	receptor antagonist activity	1/335	30/18639	0.0333333333333333	1.85462686567164	0.419882104043639	0.580598500581385
GO:0005164	tumor necrosis factor receptor binding	1/335	31/18639	0.032258064516129	1.79480019258546	0.430325410784753	0.590307223541709
GO:0005184	neuropeptide hormone activity	1/335	31/18639	0.032258064516129	1.79480019258546	0.430325410784753	0.590307223541709
GO:0005452	solute:inorganic anion antiporter activity	1/335	31/18639	0.032258064516129	1.79480019258546	0.430325410784753	0.590307223541709
GO:0017147	Wnt-protein binding	1/335	31/18639	0.032258064516129	1.79480019258546	0.430325410784753	0.590307223541709
GO:0008378	galactosyltransferase activity	1/335	32/18639	0.03125	1.73871268656716	0.440581267802547	0.599360672284633
GO:0015106	bicarbonate transmembrane transporter activity	1/335	32/18639	0.03125	1.73871268656716	0.440581267802547	0.599360672284633
GO:0051059	NF-kappaB binding	1/335	32/18639	0.03125	1.73871268656716	0.440581267802547	0.599360672284633
GO:0160041	neuropeptide activity	1/335	32/18639	0.03125	1.73871268656716	0.440581267802547	0.599360672284633
GO:0005254	chloride channel activity	2/335	83/18639	0.0240963855421687	1.34069411976263	0.441268436986368	0.599360672284633
GO:0004860	protein kinase inhibitor activity	2/335	84/18639	0.0238095238095238	1.32473347547974	0.447343846250052	0.605229909632423
GO:0180051	translation factor activity	2/335	84/18639	0.0238095238095238	1.32473347547974	0.447343846250052	0.605229909632423
GO:0019956	chemokine binding	1/335	33/18639	0.0303030303030303	1.68602442333786	0.450653029789226	0.607325372176887
GO:0140416	transcription regulator inhibitor activity	1/335	33/18639	0.0303030303030303	1.68602442333786	0.450653029789226	0.607325372176887
GO:0050660	flavin adenine dinucleotide binding	2/335	86/18639	0.0232558139534884	1.29392572023603	0.45938258799719	0.614652522607407
GO:0031625	ubiquitin protein ligase binding	6/335	302/18639	0.0198675496688742	1.10540674112879	0.459927993779063	0.614652522607407
GO:0015020	glucuronosyltransferase activity	1/335	34/18639	0.0294117647058824	1.63643546971027	0.460543991576854	0.614652522607407
GO:0015035	protein-disulfide reductase activity	1/335	34/18639	0.0294117647058824	1.63643546971027	0.460543991576854	0.614652522607407
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	1/335	34/18639	0.0294117647058824	1.63643546971027	0.460543991576854	0.614652522607407
GO:0005343	organic acid:sodium symporter activity	1/335	35/18639	0.0285714285714286	1.58968017057569	0.470257389202318	0.624168417904606
GO:0043015	gamma-tubulin binding	1/335	35/18639	0.0285714285714286	1.58968017057569	0.470257389202318	0.624168417904606
GO:0016651	oxidoreductase activity, acting on NAD(P)H	2/335	88/18639	0.0227272727272727	1.26451831750339	0.471267870041014	0.624168417904606
GO:0020037	heme binding	3/335	142/18639	0.0211267605633803	1.17546773176372	0.471292385113478	0.624168417904606
GO:0004869	cysteine-type endopeptidase inhibitor activity	1/335	36/18639	0.0277777777777778	1.5455223880597	0.479796400953405	0.630589555538761
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	1/335	36/18639	0.0277777777777778	1.5455223880597	0.479796400953405	0.630589555538761
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	1/335	36/18639	0.0277777777777778	1.5455223880597	0.479796400953405	0.630589555538761
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	1/335	36/18639	0.0277777777777778	1.5455223880597	0.479796400953405	0.630589555538761
GO:0019210	kinase inhibitor activity	2/335	90/18639	0.0222222222222222	1.23641791044776	0.482995328825302	0.633587028306955
GO:0022829	wide pore channel activity	1/335	37/18639	0.027027027027027	1.50375151270674	0.489164148396323	0.636836344138609
GO:0023023	MHC protein complex binding	1/335	37/18639	0.027027027027027	1.50375151270674	0.489164148396323	0.636836344138609
GO:0030280	structural constituent of skin epidermis	1/335	37/18639	0.027027027027027	1.50375151270674	0.489164148396323	0.636836344138609
GO:0030551	cyclic nucleotide binding	1/335	37/18639	0.027027027027027	1.50375151270674	0.489164148396323	0.636836344138609
GO:0052689	carboxylic ester hydrolase activity	2/335	92/18639	0.0217391304347826	1.20953926022064	0.494561104089248	0.640355588818706
GO:0046982	protein heterodimerization activity	7/335	369/18639	0.018970189701897	1.05547870404077	0.496017185313186	0.640355588818706
GO:0000146	microfilament motor activity	1/335	38/18639	0.0263157894736842	1.46417910447761	0.498363697384993	0.640355588818706
GO:0005109	frizzled binding	1/335	38/18639	0.0263157894736842	1.46417910447761	0.498363697384993	0.640355588818706
GO:0005501	retinoid binding	1/335	38/18639	0.0263157894736842	1.46417910447761	0.498363697384993	0.640355588818706
GO:0019840	isoprenoid binding	1/335	38/18639	0.0263157894736842	1.46417910447761	0.498363697384993	0.640355588818706
GO:0043531	ADP binding	1/335	38/18639	0.0263157894736842	1.46417910447761	0.498363697384993	0.640355588818706
GO:0051213	dioxygenase activity	2/335	93/18639	0.021505376344086	1.19653346172364	0.500282284243586	0.641625977933224
GO:0016410	N-acyltransferase activity	2/335	94/18639	0.0212765957446809	1.1838043823436	0.505961808737348	0.645949558572284
GO:0000217	DNA secondary structure binding	1/335	39/18639	0.0256410256410256	1.42663605051665	0.507398059052432	0.645949558572284
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	1/335	39/18639	0.0256410256410256	1.42663605051665	0.507398059052432	0.645949558572284
GO:0016776	phosphotransferase activity, phosphate group as acceptor	1/335	39/18639	0.0256410256410256	1.42663605051665	0.507398059052432	0.645949558572284
GO:0015036	disulfide oxidoreductase activity	1/335	40/18639	0.025	1.39097014925373	0.516270190784552	0.65002587457677
GO:0050997	quaternary ammonium group binding	1/335	40/18639	0.025	1.39097014925373	0.516270190784552	0.65002587457677
GO:0061791	GTPase motor activity	1/335	40/18639	0.025	1.39097014925373	0.516270190784552	0.65002587457677
GO:0140662	ATP-dependent protein folding chaperone	1/335	40/18639	0.025	1.39097014925373	0.516270190784552	0.65002587457677
GO:1990606	membrane scission GTPase motor activity	1/335	40/18639	0.025	1.39097014925373	0.516270190784552	0.65002587457677
GO:0046906	tetrapyrrole binding	3/335	152/18639	0.0197368421052632	1.09813432835821	0.516488438508657	0.65002587457677
GO:0004896	cytokine receptor activity	2/335	96/18639	0.0208333333333333	1.15914179104478	0.517194500206734	0.65002587457677
GO:0003774	cytoskeletal motor activity	3/335	153/18639	0.0196078431372549	1.09095697980685	0.520894744979013	0.652681564057493
GO:0044389	ubiquitin-like protein ligase binding	6/335	322/18639	0.0186335403726708	1.03674793733197	0.521893060058694	0.652681564057493
GO:0001727	lipid kinase activity	1/335	41/18639	0.024390243902439	1.35704404805242	0.524982997176679	0.652681564057493
GO:0008137	NADH dehydrogenase (ubiquinone) activity	1/335	41/18639	0.024390243902439	1.35704404805242	0.524982997176679	0.652681564057493
GO:0015175	neutral L-amino acid transmembrane transporter activity	1/335	41/18639	0.024390243902439	1.35704404805242	0.524982997176679	0.652681564057493
GO:0140318	protein transporter activity	1/335	41/18639	0.024390243902439	1.35704404805242	0.524982997176679	0.652681564057493
GO:0008514	organic anion transmembrane transporter activity	5/335	269/18639	0.0185873605947955	1.03417854963103	0.532504835610117	0.657396675663283
GO:0016859	cis-trans isomerase activity	1/335	42/18639	0.0238095238095238	1.32473347547974	0.533539330973099	0.657396675663283
GO:0019894	kinesin binding	1/335	42/18639	0.0238095238095238	1.32473347547974	0.533539330973099	0.657396675663283
GO:0031492	nucleosomal DNA binding	1/335	42/18639	0.0238095238095238	1.32473347547974	0.533539330973099	0.657396675663283
GO:0048487	beta-tubulin binding	1/335	42/18639	0.0238095238095238	1.32473347547974	0.533539330973099	0.657396675663283
GO:0015631	tubulin binding	7/335	385/18639	0.0181818181818182	1.01161465400271	0.540936314832113	0.665322740167839
GO:0005245	voltage-gated calcium channel activity	1/335	43/18639	0.0232558139534884	1.29392572023603	0.54194199398993	0.665373622514327
GO:0008238	exopeptidase activity	2/335	102/18639	0.0196078431372549	1.09095697980685	0.549861176126204	0.668309718967389
GO:0015171	amino acid transmembrane transporter activity	2/335	102/18639	0.0196078431372549	1.09095697980685	0.549861176126204	0.668309718967389
GO:0003954	NADH dehydrogenase activity	1/335	44/18639	0.0227272727272727	1.26451831750339	0.550193738021624	0.668309718967389
GO:0016790	thiolester hydrolase activity	1/335	44/18639	0.0227272727272727	1.26451831750339	0.550193738021624	0.668309718967389
GO:0030547	signaling receptor inhibitor activity	1/335	44/18639	0.0227272727272727	1.26451831750339	0.550193738021624	0.668309718967389
GO:0043014	alpha-tubulin binding	1/335	44/18639	0.0227272727272727	1.26451831750339	0.550193738021624	0.668309718967389
GO:0099106	ion channel regulator activity	3/335	160/18639	0.01875	1.0432276119403	0.551113376945571	0.668309718967389
GO:0005253	monoatomic anion channel activity	2/335	103/18639	0.0194174757281553	1.08036516446892	0.55515282496313	0.672027103902737
GO:0030291	protein serine/threonine kinase inhibitor activity	1/335	46/18639	0.0217391304347826	1.20953926022064	0.566255231525713	0.684266391861194
GO:0015081	sodium ion transmembrane transporter activity	3/335	164/18639	0.0182926829268293	1.01778303603932	0.567869021274898	0.685016826363076
GO:0004497	monooxygenase activity	2/335	106/18639	0.0188679245283019	1.04978879188961	0.570762572258282	0.687305715284842
GO:0043495	protein-membrane adaptor activity	1/335	47/18639	0.0212765957446809	1.1838043823436	0.574070242413621	0.690084437744597
GO:0140693	molecular condensate scaffold activity	1/335	48/18639	0.0208333333333333	1.15914179104478	0.581744858850338	0.698093830620406
GO:0016247	channel regulator activity	3/335	168/18639	0.0178571428571429	0.993550106609808	0.584236359535036	0.699866472359678
GO:0016763	pentosyltransferase activity	1/335	49/18639	0.0204081632653061	1.13548583612549	0.58928159556623	0.704686830053204
GO:0141108	transporter regulator activity	3/335	170/18639	0.0176470588235294	0.981861281826163	0.592271193803915	0.707036546236507
GO:0000287	magnesium ion binding	4/335	230/18639	0.0173913043478261	0.967631408176509	0.595484440562717	0.709644670100647
GO:0015605	organophosphate ester transmembrane transporter activity	1/335	50/18639	0.02	1.11277611940299	0.596682922380932	0.709846924901453
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	6/335	349/18639	0.0171919770773639	0.956541076850704	0.60064868666095	0.713334929080991
GO:0003743	translation initiation factor activity	1/335	51/18639	0.0196078431372549	1.09095697980685	0.603951265003041	0.713572556253593
GO:0016597	amino acid binding	1/335	51/18639	0.0196078431372549	1.09095697980685	0.603951265003041	0.713572556253593
GO:0016830	carbon-carbon lyase activity	1/335	51/18639	0.0196078431372549	1.09095697980685	0.603951265003041	0.713572556253593
GO:0005246	calcium channel regulator activity	1/335	53/18639	0.0188679245283019	1.04978879188961	0.618098484647682	0.725319650351872
GO:0005544	calcium-dependent phospholipid binding	1/335	53/18639	0.0188679245283019	1.04978879188961	0.618098484647682	0.725319650351872
GO:0016251	RNA polymerase II general transcription initiation factor activity	1/335	53/18639	0.0188679245283019	1.04978879188961	0.618098484647682	0.725319650351872
GO:1901505	carbohydrate derivative transmembrane transporter activity	1/335	53/18639	0.0188679245283019	1.04978879188961	0.618098484647682	0.725319650351872
GO:0009055	electron transfer activity	2/335	116/18639	0.0172413793103448	0.959289758106022	0.61990059810958	0.726199342437369
GO:0016853	isomerase activity	3/335	180/18639	0.0166666666666667	0.927313432835821	0.630918141823697	0.7378534200989
GO:0030170	pyridoxal phosphate binding	1/335	56/18639	0.0178571428571429	0.993550106609808	0.638380125062353	0.74531689728092
GO:0051082	unfolded protein binding	2/335	121/18639	0.0165289256198347	0.919649685457012	0.642800390086565	0.747866217318449
GO:0015932	nucleobase-containing compound transmembrane transporter activity	1/335	57/18639	0.0175438596491228	0.976119402985075	0.644899129426778	0.747866217318449
GO:0016504	peptidase activator activity	1/335	57/18639	0.0175438596491228	0.976119402985075	0.644899129426778	0.747866217318449
GO:0070279	vitamin B6 binding	1/335	57/18639	0.0175438596491228	0.976119402985075	0.644899129426778	0.747866217318449
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	2/335	122/18639	0.0163934426229508	0.912111573281135	0.647247879157275	0.749330598353221
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	1/335	58/18639	0.0172413793103448	0.959289758106022	0.651300958704683	0.752759902020488
GO:0036002	pre-mRNA binding	1/335	59/18639	0.0169491525423729	0.943030609663547	0.657587712853218	0.758755053292175
GO:0019905	syntaxin binding	1/335	61/18639	0.0163934426229508	0.912111573281135	0.669824208642022	0.771583812959925
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	2/335	128/18639	0.015625	0.869356343283582	0.673016273393144	0.773968714402115
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	2/335	132/18639	0.0151515151515152	0.843012211668928	0.689334330139749	0.791415453904204
GO:0019843	rRNA binding	1/335	65/18639	0.0153846153846154	0.855981630309989	0.693004612915319	0.792990353087181
GO:0160215	deacylase activity	1/335	65/18639	0.0153846153846154	0.855981630309989	0.693004612915319	0.792990353087181
GO:0015297	antiporter activity	2/335	135/18639	0.0148148148148148	0.824278606965174	0.70112959423639	0.800959304674022
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	1/335	67/18639	0.0149253731343284	0.830429939852974	0.703978956937123	0.802343941345423
GO:0016779	nucleotidyltransferase activity	2/335	136/18639	0.0147058823529412	0.818217734855136	0.704978057361277	0.802343941345423
GO:0003777	microtubule motor activity	1/335	68/18639	0.0147058823529412	0.818217734855136	0.709318556841606	0.802343941345423
GO:0005548	phospholipid transporter activity	1/335	68/18639	0.0147058823529412	0.818217734855136	0.709318556841606	0.802343941345423
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	1/335	68/18639	0.0147058823529412	0.818217734855136	0.709318556841606	0.802343941345423
GO:0140223	general transcription initiation factor activity	1/335	68/18639	0.0147058823529412	0.818217734855136	0.709318556841606	0.802343941345423
GO:0008080	N-acetyltransferase activity	1/335	69/18639	0.0144927536231884	0.806359506813757	0.714562123879356	0.806952316655902
GO:0022804	active transmembrane transporter activity	7/335	457/18639	0.0153172866520788	0.852235540024168	0.717513401195086	0.808961187621911
GO:0016782	transferase activity, transferring sulphur-containing groups	1/335	70/18639	0.0142857142857143	0.794840085287846	0.719711380126013	0.810115582849835
GO:0140299	molecular sensor activity	1/335	71/18639	0.0140845070422535	0.783645154509144	0.724768016867775	0.814478716024047
GO:0022843	voltage-gated monoatomic cation channel activity	2/335	143/18639	0.013986013986014	0.778165118463626	0.73077531923203	0.81989426060179
GO:0031491	nucleosome binding	1/335	74/18639	0.0135135135135135	0.751875756353368	0.739398672542116	0.828222539048799
GO:0019003	GDP binding	1/335	75/18639	0.0133333333333333	0.741850746268657	0.744101147344077	0.832139046462582
GO:0051536	iron-sulfur cluster binding	1/335	76/18639	0.0131578947368421	0.732089552238806	0.74871901610295	0.835948416037275
GO:0051540	metal cluster binding	1/335	77/18639	0.012987012987013	0.722581895716224	0.753253796558993	0.83965285884605
GO:0000049	tRNA binding	1/335	80/18639	0.0125	0.695485074626866	0.766374381214068	0.846668950000323
GO:0033192	calmodulin-dependent protein phosphatase activity	1/335	81/18639	0.0123456790123457	0.686898839137645	0.770591450145222	0.846668950000323
GO:0140791	histone H2AXS140 phosphatase activity	1/335	81/18639	0.0123456790123457	0.686898839137645	0.770591450145222	0.846668950000323
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	1/335	81/18639	0.0123456790123457	0.686898839137645	0.770591450145222	0.846668950000323
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	1/335	81/18639	0.0123456790123457	0.686898839137645	0.770591450145222	0.846668950000323
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	1/335	81/18639	0.0123456790123457	0.686898839137645	0.770591450145222	0.846668950000323
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	1/335	81/18639	0.0123456790123457	0.686898839137645	0.770591450145222	0.846668950000323
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	1/335	81/18639	0.0123456790123457	0.686898839137645	0.770591450145222	0.846668950000323
GO:1990439	MAP kinase serine/threonine phosphatase activity	1/335	81/18639	0.0123456790123457	0.686898839137645	0.770591450145222	0.846668950000323
GO:0140375	immune receptor activity	2/335	156/18639	0.0128205128205128	0.713318025258324	0.773618530970557	0.84717196365372
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	1/335	82/18639	0.0121951219512195	0.67852202402621	0.774732621834054	0.84717196365372
GO:0033549	MAP kinase phosphatase activity	1/335	82/18639	0.0121951219512195	0.67852202402621	0.774732621834054	0.84717196365372
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	1/335	83/18639	0.0120481927710843	0.670347059881316	0.778799258234636	0.848928101393205
GO:0008135	translation factor activity, RNA binding	1/335	83/18639	0.0120481927710843	0.670347059881316	0.778799258234636	0.848928101393205
GO:0017018	myosin phosphatase activity	1/335	84/18639	0.0119047619047619	0.662366737739872	0.782792696933245	0.851935269533027
GO:0015079	potassium ion transmembrane transporter activity	2/335	160/18639	0.0125	0.695485074626866	0.785551658813545	0.853591566269837
GO:0004197	cysteine-type endopeptidase activity	1/335	88/18639	0.0113636363636364	0.632259158751696	0.798060397688265	0.865820242775004
GO:0003727	single-stranded RNA binding	1/335	89/18639	0.0112359550561798	0.625155123260104	0.801707088797878	0.868411132292834
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	1/335	91/18639	0.010989010989011	0.61141545022142	0.808804669480704	0.874726053200135
GO:0005216	monoatomic ion channel activity	6/335	448/18639	0.0133928571428571	0.745162579957356	0.819269487992654	0.884475282898702
GO:0005244	voltage-gated monoatomic ion channel activity	2/335	173/18639	0.0115606936416185	0.64322319040635	0.820597560106513	0.884475282898702
GO:0046873	metal ion transmembrane transporter activity	6/335	450/18639	0.0133333333333333	0.741850746268657	0.822478990137587	0.884475282898702
GO:0003823	antigen binding	2/335	174/18639	0.0114942528735632	0.639526505404014	0.823069184257114	0.884475282898702
GO:0016407	acetyltransferase activity	1/335	96/18639	0.0104166666666667	0.579570895522388	0.82545999829785	0.884475282898702
GO:0022832	voltage-gated channel activity	2/335	175/18639	0.0114285714285714	0.635872068230277	0.825510264038788	0.884475282898702
GO:0005249	voltage-gated potassium channel activity	1/335	98/18639	0.0102040816326531	0.567742918062747	0.831709718164821	0.889735977571669
GO:0004722	protein serine/threonine phosphatase activity	1/335	103/18639	0.00970873786407767	0.540182582234459	0.84637508717967	0.904022925934942
GO:0015078	proton transmembrane transporter activity	2/335	185/18639	0.0108108108108108	0.601500605082695	0.848305709414148	0.904684605093914
GO:0008234	cysteine-type peptidase activity	2/335	187/18639	0.0106951871657754	0.595067443531008	0.852527449058385	0.907142885705848
GO:0000149	SNARE binding	1/335	106/18639	0.00943396226415094	0.524894395944804	0.854555252425636	0.907142885705848
GO:0046943	carboxylic acid transmembrane transporter activity	2/335	188/18639	0.0106382978723404	0.591902191171801	0.854598010795997	0.907142885705848
GO:0005342	organic acid transmembrane transporter activity	2/335	189/18639	0.0105820105820106	0.588770433546553	0.856642076132707	0.907142885705848
GO:0019888	protein phosphatase regulator activity	1/335	107/18639	0.00934579439252336	0.519988840842516	0.857184292000309	0.907142885705848
GO:0004843	cysteine-type deubiquitinase activity	1/335	108/18639	0.00925925925925926	0.515174129353234	0.859765948711937	0.9084816303388
GO:0101005	deubiquitinase activity	1/335	115/18639	0.00869565217391304	0.483815704088254	0.876580460295217	0.924344020883503
GO:0016829	lyase activity	2/335	200/18639	0.01	0.556388059701493	0.877457005331441	0.924344020883503
GO:0019208	phosphatase regulator activity	1/335	117/18639	0.00854700854700855	0.475545350172216	0.881004211307735	0.926666014942587
GO:0022853	active monoatomic ion transmembrane transporter activity	1/335	118/18639	0.00847457627118644	0.471515304831773	0.883156440506089	0.92751589642192
GO:0008528	G protein-coupled peptide receptor activity	1/335	122/18639	0.00819672131147541	0.456055786640568	0.891384149606569	0.933315725688213
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	1/335	122/18639	0.00819672131147541	0.456055786640568	0.891384149606569	0.933315725688213
GO:0005267	potassium channel activity	1/335	124/18639	0.00806451612903226	0.448700048146365	0.895278747382375	0.935973235899756
GO:0019783	ubiquitin-like protein peptidase activity	1/335	127/18639	0.0078740157480315	0.438100834410624	0.900861117530404	0.940384525107381
GO:0001653	peptide receptor activity	1/335	128/18639	0.0078125	0.434678171641791	0.902655171421249	0.940833940000999
GO:0005262	calcium channel activity	1/335	131/18639	0.00763358778625954	0.424723709695796	0.907845427888168	0.944816508661894
GO:0099094	ligand-gated monoatomic cation channel activity	1/335	136/18639	0.00735294117647059	0.409108867427568	0.915889882536946	0.951753040588092
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	2/335	229/18639	0.00873362445414847	0.485928436420517	0.919703298443011	0.953543107844269
GO:0140767	enzyme-substrate adaptor activity	1/335	139/18639	0.00719424460431655	0.400279179641362	0.920376391049686	0.953543107844269
GO:0015085	calcium ion transmembrane transporter activity	1/335	147/18639	0.00680272108843537	0.378495278708498	0.931207811963048	0.960658545551316
GO:0019001	guanyl nucleotide binding	4/335	400/18639	0.01	0.556388059701493	0.931421111556276	0.960658545551316
GO:0032561	guanyl ribonucleotide binding	4/335	400/18639	0.01	0.556388059701493	0.931421111556276	0.960658545551316
GO:0140104	molecular carrier activity	2/335	249/18639	0.00803212851405622	0.446898039920878	0.940411761620741	0.968483754504943
GO:0005261	monoatomic cation channel activity	3/335	341/18639	0.00879765395894428	0.489490961614216	0.946578855039531	0.973382131113675
GO:0003730	mRNA 3'-UTR binding	2/335	262/18639	0.00763358778625954	0.424723709695796	0.951040027745718	0.97489049913055
GO:0015399	primary active transmembrane transporter activity	1/335	166/18639	0.00602409638554217	0.335173529940658	0.951403057745341	0.97489049913055
GO:0016874	ligase activity	1/335	167/18639	0.00598802395209581	0.333166502815265	0.952284342628972	0.97489049913055
GO:0061630	ubiquitin protein ligase activity	3/335	353/18639	0.0084985835694051	0.472851042239229	0.954558246742198	0.975770652225358
GO:0045182	translation regulator activity	3/335	356/18639	0.00842696629213483	0.468866342445078	0.956371768341754	0.976178284254158
GO:0003735	structural constituent of ribosome	1/335	175/18639	0.00571428571428571	0.317936034115139	0.958784458172409	0.977195385729634
GO:0043021	ribonucleoprotein complex binding	1/335	177/18639	0.00564971751412429	0.314343536554516	0.960266511758878	0.977262379223637
GO:0004842	ubiquitin-protein transferase activity	4/335	449/18639	0.0089086859688196	0.495668650068145	0.96246237775601	0.977660651458517
GO:0061659	ubiquitin-like protein ligase activity	3/335	372/18639	0.00806451612903226	0.448700048146365	0.964953928494483	0.977660651458517
GO:0015276	ligand-gated monoatomic ion channel activity	1/335	186/18639	0.00537634408602151	0.29913336543091	0.966304978981395	0.977660651458517
GO:0022834	ligand-gated channel activity	1/335	188/18639	0.00531914893617021	0.2959510955859	0.967517320758981	0.977660651458517
GO:0005525	GTP binding	3/335	378/18639	0.00793650793650794	0.441577825159915	0.967742354994445	0.977660651458517
GO:0019787	ubiquitin-like protein transferase activity	4/335	479/18639	0.00835073068893528	0.464624684510641	0.974418337247493	0.982965866521594
GO:0022836	gated channel activity	2/335	318/18639	0.00628930817610063	0.349929597296536	0.979404743664312	0.985216446380572
GO:0016755	aminoacyltransferase activity	4/335	496/18639	0.00806451612903226	0.448700048146365	0.979505046691409	0.985216446380572
GO:0016887	ATP hydrolysis activity	3/335	417/18639	0.00719424460431655	0.400279179641362	0.981357882088622	0.985643287687263
GO:0003924	GTPase activity	2/335	331/18639	0.00604229607250755	0.336186138792443	0.983221882179247	0.986080085325117
GO:0042393	histone binding	1/335	247/18639	0.00404858299595142	0.225258323765786	0.988999629551818	0.990435042657118
GO:0030371	translation repressor activity	1/335	329/18639	0.00303951367781155	0.169114911763372	0.997571642893784	0.997571642893784