ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0003712	transcription coregulator activity	221/5114	495/18639	0.446464646464646	1.62723006363992	7.46097192440385e-17	1.01916876487357e-13
GO:0030695	GTPase regulator activity	216/5114	489/18639	0.441717791411043	1.60992919712758	7.02952074810271e-16	3.14446873180049e-13
GO:0004674	protein serine/threonine kinase activity	196/5114	433/18639	0.452655889145497	1.64979529092353	7.8183741707936e-16	3.14446873180049e-13
GO:0060589	nucleoside-triphosphatase regulator activity	216/5114	490/18639	0.440816326530612	1.60664362733752	9.20781473440847e-16	3.14446873180049e-13
GO:0003725	double-stranded RNA binding	53/5114	75/18639	0.706666666666667	2.57558858036762	7.79033825985294e-15	2.12832041259182e-12
GO:0106310	protein serine kinase activity	165/5114	361/18639	0.457063711911357	1.66586048617829	5.45579603465537e-14	1.24210289722321e-11
GO:0051020	GTPase binding	148/5114	315/18639	0.46984126984127	1.71243086205933	7.12063193329379e-14	1.38954046012562e-11
GO:0031267	small GTPase binding	136/5114	283/18639	0.480565371024735	1.75151700245014	8.59826414847609e-14	1.46815360335229e-11
GO:0044389	ubiquitin-like protein ligase binding	146/5114	322/18639	0.453416149068323	1.65256621088863	3.28294327465482e-12	4.98277834797609e-10
GO:0005085	guanyl-nucleotide exchange factor activity	112/5114	230/18639	0.48695652173913	1.77481083470779	4.52237111726627e-12	6.17755894618572e-10
GO:0031625	ubiquitin protein ligase binding	137/5114	302/18639	0.45364238410596	1.65339076991611	1.45517462520358e-11	1.80706230729826e-09
GO:0141003	histone H2AX kinase activity	155/5114	354/18639	0.437853107344633	1.59584357993676	2.04286491208597e-11	2.23187141485162e-09
GO:0140996	histone H3 kinase activity	156/5114	357/18639	0.436974789915966	1.59264237568316	2.12403575351911e-11	2.23187141485162e-09
GO:0140297	DNA-binding transcription factor binding	200/5114	488/18639	0.409836065573771	1.49372984478481	4.21927044672122e-11	3.89449683045294e-09
GO:0016922	nuclear receptor binding	74/5114	137/18639	0.54014598540146	1.96867051660106	4.27653385481656e-11	3.89449683045294e-09
GO:0035173	histone kinase activity	156/5114	360/18639	0.433333333333333	1.5793703558858	4.60891261672123e-11	3.93485914652575e-09
GO:0043130	ubiquitin binding	58/5114	100/18639	0.58	2.11392647633946	1.27169782925796e-10	8.74606761165684e-09
GO:0004677	DNA-dependent protein kinase activity	114/5114	246/18639	0.463414634146341	1.68900769766399	1.49291126471913e-10	8.74606761165684e-09
GO:0140857	histone H3T45 kinase activity	114/5114	246/18639	0.463414634146341	1.68900769766399	1.49291126471913e-10	8.74606761165684e-09
GO:0032182	ubiquitin-like protein binding	66/5114	120/18639	0.55	2.00458545170121	1.68445843648145e-10	8.74606761165684e-09
GO:0035402	histone H3T11 kinase activity	114/5114	247/18639	0.461538461538462	1.6821696098192	2.03009785253943e-10	8.74606761165684e-09
GO:0035403	histone H3T6 kinase activity	114/5114	247/18639	0.461538461538462	1.6821696098192	2.03009785253943e-10	8.74606761165684e-09
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	150/5114	349/18639	0.429799426934097	1.5664903243302	2.22061432304769e-10	8.74606761165684e-09
GO:0004676	3-phosphoinositide-dependent protein kinase activity	113/5114	245/18639	0.461224489795918	1.68102527675129	2.56107397120259e-10	8.74606761165684e-09
GO:0004711	ribosomal protein S6 kinase activity	113/5114	245/18639	0.461224489795918	1.68102527675129	2.56107397120259e-10	8.74606761165684e-09
GO:0035175	histone H3S10 kinase activity	113/5114	245/18639	0.461224489795918	1.68102527675129	2.56107397120259e-10	8.74606761165684e-09
GO:0035979	histone H2AXS139 kinase activity	113/5114	245/18639	0.461224489795918	1.68102527675129	2.56107397120259e-10	8.74606761165684e-09
GO:0044022	histone H3S28 kinase activity	113/5114	245/18639	0.461224489795918	1.68102527675129	2.56107397120259e-10	8.74606761165684e-09
GO:0044023	histone H4S1 kinase activity	113/5114	245/18639	0.461224489795918	1.68102527675129	2.56107397120259e-10	8.74606761165684e-09
GO:0044024	histone H2AS1 kinase activity	113/5114	245/18639	0.461224489795918	1.68102527675129	2.56107397120259e-10	8.74606761165684e-09
GO:0044025	histone H2BS14 kinase activity	113/5114	245/18639	0.461224489795918	1.68102527675129	2.56107397120259e-10	8.74606761165684e-09
GO:0072354	histone H3T3 kinase activity	113/5114	245/18639	0.461224489795918	1.68102527675129	2.56107397120259e-10	8.74606761165684e-09
GO:0072371	histone H2AS121 kinase activity	113/5114	245/18639	0.461224489795918	1.68102527675129	2.56107397120259e-10	8.74606761165684e-09
GO:0072518	Rho-dependent protein serine/threonine kinase activity	113/5114	245/18639	0.461224489795918	1.68102527675129	2.56107397120259e-10	8.74606761165684e-09
GO:0140823	histone H2BS36 kinase activity	113/5114	245/18639	0.461224489795918	1.68102527675129	2.56107397120259e-10	8.74606761165684e-09
GO:0140855	histone H3S57 kinase activity	113/5114	245/18639	0.461224489795918	1.68102527675129	2.56107397120259e-10	8.74606761165684e-09
GO:0140995	histone H2A kinase activity	113/5114	245/18639	0.461224489795918	1.68102527675129	2.56107397120259e-10	8.74606761165684e-09
GO:0140997	histone H4 kinase activity	113/5114	245/18639	0.461224489795918	1.68102527675129	2.56107397120259e-10	8.74606761165684e-09
GO:0140998	histone H2B kinase activity	113/5114	245/18639	0.461224489795918	1.68102527675129	2.56107397120259e-10	8.74606761165684e-09
GO:1990244	histone H2AT120 kinase activity	113/5114	245/18639	0.461224489795918	1.68102527675129	2.56107397120259e-10	8.74606761165684e-09
GO:0004679	AMP-activated protein kinase activity	114/5114	248/18639	0.459677419354839	1.67538666784412	2.75109541786222e-10	9.16584473365802e-09
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	112/5114	243/18639	0.460905349794239	1.67986210692507	3.2305829021888e-10	1.05070862961664e-08
GO:0019787	ubiquitin-like protein transferase activity	193/5114	479/18639	0.402922755741127	1.46853289876005	5.00599304459524e-10	1.59027592998072e-08
GO:0003713	transcription coactivator activity	116/5114	256/18639	0.453125	1.6515050596402	5.67017326876411e-10	1.76033106480268e-08
GO:0016755	aminoacyltransferase activity	195/5114	496/18639	0.393145161290323	1.4328964922351	4.2525209805144e-09	1.29087636875171e-07
GO:0004842	ubiquitin-protein transferase activity	179/5114	449/18639	0.398663697104677	1.45300990424992	5.47442692859632e-09	1.625666779231e-07
GO:0023026	MHC class II protein complex binding	22/5114	27/18639	0.814814814814815	2.96975622474254	7.56120336824376e-09	2.19757527681297e-07
GO:0023023	MHC protein complex binding	27/5114	37/18639	0.72972972972973	2.65964654525468	1.07122146348508e-08	3.04851774816797e-07
GO:0061659	ubiquitin-like protein ligase activity	152/5114	372/18639	0.408602150537634	1.48923259363922	1.15148639080754e-08	3.2100620609043e-07
GO:0035591	signaling adaptor activity	65/5114	129/18639	0.503875968992248	1.83647715800675	2.49799960344375e-08	6.82453491660833e-07
GO:0019902	phosphatase binding	87/5114	190/18639	0.457894736842105	1.66888932342589	4.28407547475132e-08	1.14746021539418e-06
GO:0019207	kinase regulator activity	121/5114	287/18639	0.421602787456446	1.53661602569431	4.49987309537092e-08	1.18208204774551e-06
GO:0031072	heat shock protein binding	65/5114	131/18639	0.49618320610687	1.80843933880054	5.33599167118206e-08	1.36569662945458e-06
GO:0140597	protein carrier chaperone	86/5114	188/18639	0.457446808510638	1.66725675866832	5.39880073137241e-08	1.36569662945458e-06
GO:0016887	ATP hydrolysis activity	164/5114	417/18639	0.393285371702638	1.43340751724002	6.96132997449359e-08	1.72894122639241e-06
GO:0035091	phosphatidylinositol binding	119/5114	284/18639	0.419014084507042	1.52718097792858	8.69282515598209e-08	2.12042842197706e-06
GO:0005096	GTPase activator activity	114/5114	271/18639	0.420664206642066	1.53319517942931	1.25624764526708e-07	3.01058646216638e-06
GO:0035259	nuclear glucocorticoid receptor binding	12/5114	12/18639	1	3.64470082127493	1.80296136121044e-07	4.24628486105769e-06
GO:0003924	GTPase activity	133/5114	331/18639	0.401812688821752	1.46448703694733	2.89650746629752e-07	6.60336408738824e-06
GO:0045296	cadherin binding	134/5114	334/18639	0.401197604790419	1.46224523967318	2.90045274702265e-07	6.60336408738824e-06
GO:0019903	protein phosphatase binding	68/5114	144/18639	0.472222222222222	1.72110872115761	2.99458000688365e-07	6.70589555639848e-06
GO:0061630	ubiquitin protein ligase activity	140/5114	353/18639	0.396600566572238	1.44549041070394	3.51135282043817e-07	7.73630314954604e-06
GO:0140713	histone chaperone activity	75/5114	164/18639	0.457317073170732	1.66678391216841	3.78622726418033e-07	8.20950229027037e-06
GO:0140030	modification-dependent protein binding	78/5114	173/18639	0.450867052023121	1.64327551479448	4.56394976276616e-07	9.69438258366586e-06
GO:0140272	exogenous protein binding	44/5114	82/18639	0.536585365853659	1.95569312361094	4.61299317670777e-07	9.69438258366586e-06
GO:0140674	ATP-dependent histone chaperone activity	70/5114	152/18639	0.460526315789474	1.67848064137661	6.61254107827262e-07	1.36859562316976e-05
GO:0140658	ATP-dependent chromatin remodeler activity	72/5114	158/18639	0.455696202531646	1.66087632361896	7.57892912842301e-07	1.54519659543669e-05
GO:0042393	histone binding	103/5114	247/18639	0.417004048582996	1.51985499834542	8.17565474378976e-07	1.64234476176718e-05
GO:0061775	cohesin loader activity	70/5114	153/18639	0.457516339869281	1.66751017966827	8.94302975453219e-07	1.77046067314362e-05
GO:0001618	virus receptor activity	43/5114	81/18639	0.530864197530864	1.9348411767262	9.1496393228206e-07	1.78548675928185e-05
GO:0001221	transcription coregulator binding	56/5114	115/18639	0.48695652173913	1.77481083470779	9.47140117865127e-07	1.82224422676586e-05
GO:0000510	H3-H4 histone complex chaperone activity	69/5114	151/18639	0.456953642384106	1.66545931568192	1.12757703896217e-06	2.05369364696311e-05
GO:0140584	chromatin extrusion motor activity	69/5114	151/18639	0.456953642384106	1.66545931568192	1.12757703896217e-06	2.05369364696311e-05
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	69/5114	151/18639	0.456953642384106	1.66545931568192	1.12757703896217e-06	2.05369364696311e-05
GO:0140849	ATP-dependent H2AZ histone chaperone activity	69/5114	151/18639	0.456953642384106	1.66545931568192	1.12757703896217e-06	2.05369364696311e-05
GO:0140104	molecular carrier activity	103/5114	249/18639	0.413654618473896	1.50764732767598	1.28053329871843e-06	2.30159011322287e-05
GO:0015616	DNA translocase activity	69/5114	152/18639	0.453947368421053	1.6545023464998	1.51524309014658e-06	2.68808059888342e-05
GO:0004386	helicase activity	70/5114	155/18639	0.451612903225806	1.64599391928545	1.60958771891654e-06	2.81884208210256e-05
GO:0140375	immune receptor activity	70/5114	156/18639	0.448717948717949	1.63544267621311	2.14246911847497e-06	3.70457318460356e-05
GO:0005543	phospholipid binding	183/5114	497/18639	0.368209255533199	1.34201257604288	2.39634686087811e-06	4.09176226494938e-05
GO:0003689	DNA clamp loader activity	71/5114	160/18639	0.44375	1.61733598944075	2.98063319306582e-06	5.02659869349125e-05
GO:0005525	GTP binding	144/5114	378/18639	0.380952380952381	1.38845745572378	3.50332949853705e-06	5.83603426219709e-05
GO:0004532	RNA exonuclease activity	25/5114	40/18639	0.625	2.27793801329683	3.68343812178761e-06	6.06214033055647e-05
GO:0008094	ATP-dependent activity, acting on DNA	88/5114	210/18639	0.419047619047619	1.52730320129616	3.94537222502748e-06	6.41592673736612e-05
GO:0140097	catalytic activity, acting on DNA	130/5114	336/18639	0.386904761904762	1.41015210346947	4.13788084048693e-06	6.64981791541782e-05
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	24/5114	38/18639	0.631578947368421	2.30191630817364	4.41932135060049e-06	7.01952670339566e-05
GO:0019001	guanyl nucleotide binding	150/5114	400/18639	0.375	1.3667628079781	6.11074542384151e-06	9.4855434647358e-05
GO:0032561	guanyl ribonucleotide binding	150/5114	400/18639	0.375	1.3667628079781	6.11074542384151e-06	9.4855434647358e-05
GO:0019887	protein kinase regulator activity	102/5114	255/18639	0.4	1.45788032850997	8.43034934345452e-06	0.000129391653968077
GO:0000149	SNARE binding	50/5114	106/18639	0.471698113207547	1.71919850060138	1.09998172861161e-05	0.000166952782364829
GO:0001222	transcription corepressor binding	28/5114	49/18639	0.571428571428571	2.08268618358568	1.15477839194885e-05	0.000173343657516717
GO:0042277	peptide binding	99/5114	249/18639	0.397590361445783	1.44909791689244	1.52576321508331e-05	0.000226542668674326
GO:0042826	histone deacetylase binding	57/5114	127/18639	0.448818897637795	1.63581060482418	1.80036009609114e-05	0.00026246160483657
GO:0042605	peptide antigen binding	26/5114	45/18639	0.577777777777778	2.10582714118107	1.80610474777728e-05	0.00026246160483657
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	32/5114	60/18639	0.533333333333333	1.9438404380133	1.95537519673103e-05	0.000281162370393115
GO:1901981	phosphatidylinositol phosphate binding	77/5114	185/18639	0.416216216216216	1.51698358507119	2.0468296831344e-05	0.000291246806996
GO:0042169	SH2 domain binding	24/5114	41/18639	0.585365853658537	2.13348340757557	2.80749697400665e-05	0.000392235999661095
GO:0015631	tubulin binding	142/5114	385/18639	0.368831168831169	1.34427926395075	2.81399179844709e-05	0.000392235999661095
GO:0005048	signal sequence binding	28/5114	51/18639	0.549019607843137	2.00101221560192	3.17782527070175e-05	0.000438475688866525
GO:0003724	RNA helicase activity	38/5114	77/18639	0.493506493506494	1.79868352218763	3.47638734659959e-05	0.000474874511545504
GO:0031593	polyubiquitin modification-dependent protein binding	31/5114	59/18639	0.525423728813559	1.91501229592412	3.86408357734819e-05	0.000522607739273033
GO:0003925	G protein activity	29/5114	54/18639	0.537037037037037	1.95733932994394	4.00686210879576e-05	0.000533306813495503
GO:0060590	ATPase regulator activity	27/5114	49/18639	0.551020408163265	2.0083045341719	4.02127392313593e-05	0.000533306813495503
GO:0019209	kinase activator activity	63/5114	148/18639	0.425675675675676	1.5514604847319	5.00344313801516e-05	0.000654588695537078
GO:0003714	transcription corepressor activity	82/5114	204/18639	0.401960784313726	1.46502680070855	5.03161149570961e-05	0.000654588695537078
GO:0000175	3'-5'-RNA exonuclease activity	21/5114	35/18639	0.6	2.18682049276496	5.35095953631555e-05	0.00068956704967991
GO:0051087	protein-folding chaperone binding	58/5114	134/18639	0.432835820895522	1.57755707189512	5.54430239046308e-05	0.00070780533321239
GO:0001217	DNA-binding transcription repressor activity	106/5114	278/18639	0.381294964028777	1.38970606854368	6.154393070443e-05	0.000778416753168994
GO:0071889	14-3-3 protein binding	20/5114	33/18639	0.606060606060606	2.20890958865147	6.59311507371849e-05	0.000820155334094965
GO:0032395	MHC class II receptor activity	9/5114	10/18639	0.9	3.28023073914744	6.6044719436637e-05	0.000820155334094965
GO:0008186	ATP-dependent activity, acting on RNA	38/5114	79/18639	0.481012658227848	1.75314723048668	7.09958066881998e-05	0.000873696143568296
GO:0061980	regulatory RNA binding	30/5114	58/18639	0.517241379310345	1.88519007996979	7.52921397336588e-05	0.000918295204251589
GO:0051219	phosphoprotein binding	43/5114	93/18639	0.462365591397849	1.68518425069701	7.94731831233234e-05	0.00095850319604342
GO:0070034	telomerase RNA binding	15/5114	22/18639	0.681818181818182	2.48502328723291	7.99922140182649e-05	0.00095850319604342
GO:0019783	ubiquitin-like protein peptidase activity	55/5114	127/18639	0.433070866141732	1.57841374149702	8.37193849181947e-05	0.00099444069389786
GO:0016779	nucleotidyltransferase activity	58/5114	136/18639	0.426470588235294	1.55435770319078	9.1616679250115e-05	0.00107886537806601
GO:0000993	RNA polymerase II complex binding	21/5114	36/18639	0.583333333333333	2.12607547907704	9.52817526449176e-05	0.00111243482147827
GO:0140098	catalytic activity, acting on RNA	139/5114	387/18639	0.359173126614987	1.30907858955353	0.000141507326666375	0.00163812718835821
GO:0008139	nuclear localization sequence binding	16/5114	25/18639	0.64	2.33260852561596	0.000144073929019252	0.00164004155866915
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	16/5114	25/18639	0.64	2.33260852561596	0.000144073929019252	0.00164004155866915
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	101/5114	268/18639	0.376865671641791	1.37356262294316	0.000151468673290036	0.00170996865879496
GO:0003697	single-stranded DNA binding	52/5114	121/18639	0.429752066115702	1.5663177083165	0.000163290542484995	0.00182479544791215
GO:0043021	ribonucleoprotein complex binding	71/5114	177/18639	0.401129943502825	1.46199863452271	0.000166995436246655	0.00182479544791215
GO:0001098	basal transcription machinery binding	30/5114	60/18639	0.5	1.82235041063747	0.000167370293335881	0.00182479544791215
GO:0001099	basal RNA polymerase II transcription machinery binding	30/5114	60/18639	0.5	1.82235041063747	0.000167370293335881	0.00182479544791215
GO:0043175	RNA polymerase core enzyme binding	23/5114	42/18639	0.547619047619048	1.99590759260294	0.000168319345854269	0.00182479544791215
GO:0002020	protease binding	57/5114	136/18639	0.419117647058824	1.52755843244611	0.000183867766247381	0.00197766432042459
GO:0032813	tumor necrosis factor receptor superfamily binding	26/5114	50/18639	0.52	1.89524442706296	0.000199783589071948	0.0021320654896272
GO:0008234	cysteine-type peptidase activity	74/5114	187/18639	0.39572192513369	1.44228802553126	0.000202824440088858	0.00214773786946806
GO:0052742	phosphatidylinositol kinase activity	16/5114	26/18639	0.615384615384615	2.24289281309227	0.000279240485645293	0.00293417310301131
GO:0003727	single-stranded RNA binding	40/5114	89/18639	0.449438202247191	1.63806778484267	0.000292592799279196	0.00305100583065177
GO:0005164	tumor necrosis factor receptor binding	18/5114	31/18639	0.580645161290323	2.11627789622415	0.000325859051958221	0.00337214746193129
GO:0001727	lipid kinase activity	22/5114	41/18639	0.536585365853659	1.95569312361094	0.000342350667613619	0.00351617302225717
GO:0140463	chromatin-protein adaptor activity	27/5114	54/18639	0.5	1.82235041063747	0.00034954877051789	0.00356331060095103
GO:0043539	protein serine/threonine kinase activator activity	34/5114	73/18639	0.465753424657534	1.69753188936093	0.000361158942150853	0.00365439344428196
GO:0003779	actin binding	154/5114	443/18639	0.347629796839729	1.2670066060414	0.000374374274096423	0.00376025925305672
GO:0004713	protein tyrosine kinase activity	57/5114	140/18639	0.407142857142857	1.48391390580479	0.000449498524841037	0.00448186120388947
GO:0004197	cysteine-type endopeptidase activity	39/5114	88/18639	0.443181818181818	1.61526513670139	0.000489586452262234	0.00484619633181313
GO:0016004	phospholipase activator activity	13/5114	20/18639	0.65	2.36905553382871	0.000497256867225073	0.00488671137143489
GO:0001671	ATPase activator activity	16/5114	27/18639	0.592592592592593	2.15982270890366	0.000511219973749034	0.00493309661853688
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	16/5114	27/18639	0.592592592592593	2.15982270890366	0.000511219973749034	0.00493309661853688
GO:0019208	phosphatase regulator activity	49/5114	117/18639	0.418803418803419	1.52641316446557	0.000512810922278358	0.00493309661853688
GO:0008017	microtubule binding	101/5114	276/18639	0.365942028985507	1.33374921358249	0.000516785382547557	0.00493656526265708
GO:0035198	miRNA binding	22/5114	42/18639	0.523809523809524	1.9091290016202	0.000533785121548908	0.00506354497247089
GO:0019905	syntaxin binding	29/5114	61/18639	0.475409836065574	1.73272661995038	0.000628703357522335	0.00592281921638283
GO:0004715	non-membrane spanning protein tyrosine kinase activity	23/5114	45/18639	0.511111111111111	1.86284708642941	0.000633320093361228	0.00592544690090026
GO:0019003	GDP binding	34/5114	75/18639	0.453333333333333	1.6522643723113	0.000667405750205051	0.00610105728392147
GO:0030295	protein kinase activator activity	56/5114	139/18639	0.402877697841727	1.46836867619709	0.000681681181423837	0.00610105728392147
GO:0061809	NAD+ nucleosidase activity, cyclic ADP-ribose generating	11/5114	16/18639	0.6875	2.50573181462652	0.000682616714428174	0.00610105728392147
GO:0140328	floppase activity	11/5114	16/18639	0.6875	2.50573181462652	0.000682616714428174	0.00610105728392147
GO:0061791	GTPase motor activity	21/5114	40/18639	0.525	1.91346793116934	0.000683354146734982	0.00610105728392147
GO:0071949	FAD binding	21/5114	40/18639	0.525	1.91346793116934	0.000683354146734982	0.00610105728392147
GO:1990606	membrane scission GTPase motor activity	21/5114	40/18639	0.525	1.91346793116934	0.000683354146734982	0.00610105728392147
GO:0032452	histone demethylase activity	17/5114	30/18639	0.566666666666667	2.06533046538913	0.00070292744363643	0.00623505771433353
GO:0061631	ubiquitin conjugating enzyme activity	19/5114	35/18639	0.542857142857143	1.97855187440639	0.000711723705838587	0.00627235214306781
GO:0034236	protein kinase A catalytic subunit binding	10/5114	14/18639	0.714285714285714	2.60335772948209	0.000768856578205577	0.00673242362710781
GO:0004527	exonuclease activity	37/5114	84/18639	0.44047619047619	1.60540393318062	0.000776871628404007	0.00675927798980811
GO:0045309	protein phosphorylated amino acid binding	28/5114	59/18639	0.474576271186441	1.72968852535081	0.000802348875976641	0.00689313562631504
GO:0070063	RNA polymerase binding	28/5114	59/18639	0.474576271186441	1.72968852535081	0.000802348875976641	0.00689313562631504
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	8/5114	10/18639	0.8	2.91576065701995	0.000824594959701538	0.00699625288790249
GO:1905394	retromer complex binding	8/5114	10/18639	0.8	2.91576065701995	0.000824594959701538	0.00699625288790249
GO:0051019	mitogen-activated protein kinase binding	16/5114	28/18639	0.571428571428571	2.08268618358568	0.000890205805740568	0.00746025233522464
GO:0141052	histone H3 demethylase activity	16/5114	28/18639	0.571428571428571	2.08268618358568	0.000890205805740568	0.00746025233522464
GO:0046332	SMAD binding	35/5114	79/18639	0.443037974683544	1.6147408701851	0.000937052866246738	0.00780496472739661
GO:0140457	protein demethylase activity	17/5114	31/18639	0.548387096774194	1.99870690198948	0.00116079620495997	0.00960998555136558
GO:0017124	SH3 domain binding	47/5114	115/18639	0.408695652173913	1.48957337912975	0.00123525557394928	0.0101039467905073
GO:0101005	deubiquitinase activity	47/5114	115/18639	0.408695652173913	1.48957337912975	0.00123525557394928	0.0101039467905073
GO:0001784	phosphotyrosine residue binding	23/5114	47/18639	0.48936170212766	1.78357699764518	0.00136781764816167	0.0111216601630288
GO:0060229	lipase activator activity	14/5114	24/18639	0.583333333333333	2.12607547907704	0.00142205291278982	0.0114942265021946
GO:0044183	protein folding chaperone	33/5114	75/18639	0.44	1.60366836136097	0.00149070239330048	0.0119782321720497
GO:0019888	protein phosphatase regulator activity	44/5114	107/18639	0.411214953271028	1.49875547790745	0.00150103976480733	0.0119907620978176
GO:0051879	Hsp90 protein binding	21/5114	42/18639	0.5	1.82235041063747	0.00154903047807592	0.0123021839130913
GO:0004860	protein kinase inhibitor activity	36/5114	84/18639	0.428571428571429	1.56201463768926	0.00165160148892707	0.0130409689819328
GO:0019210	kinase inhibitor activity	38/5114	90/18639	0.422222222222222	1.53887368009386	0.00173290640538322	0.0135721278148287
GO:0061578	K63-linked deubiquitinase activity	10/5114	15/18639	0.666666666666667	2.42980054751662	0.00173874258242681	0.0135721278148287
GO:0042578	phosphoric ester hydrolase activity	125/5114	363/18639	0.34435261707989	1.25506226627925	0.00186329235520754	0.0144616895296222
GO:0030331	nuclear estrogen receptor binding	20/5114	40/18639	0.5	1.82235041063747	0.00199066468728997	0.0152557617838318
GO:0032451	demethylase activity	20/5114	40/18639	0.5	1.82235041063747	0.00199066468728997	0.0152557617838318
GO:0004535	poly(A)-specific ribonuclease activity	9/5114	13/18639	0.692307692307692	2.5232544147288	0.00203261247778725	0.0152557617838318
GO:0032396	inhibitory MHC class I receptor activity	9/5114	13/18639	0.692307692307692	2.5232544147288	0.00203261247778725	0.0152557617838318
GO:0043560	insulin receptor substrate binding	9/5114	13/18639	0.692307692307692	2.5232544147288	0.00203261247778725	0.0152557617838318
GO:0140806	NAD+-protein-aspartate ADP-ribosyltransferase activity	9/5114	13/18639	0.692307692307692	2.5232544147288	0.00203261247778725	0.0152557617838318
GO:0052745	inositol phosphate phosphatase activity	12/5114	20/18639	0.6	2.18682049276496	0.00225098423366765	0.0166606124769557
GO:0004712	protein serine/threonine/tyrosine kinase activity	21/5114	43/18639	0.488372093023256	1.77997016852962	0.00225272985086175	0.0166606124769557
GO:1990841	promoter-specific chromatin binding	30/5114	68/18639	0.441176470588235	1.60795624468012	0.00227707431125609	0.0166606124769557
GO:0005225	volume-sensitive anion channel activity	8/5114	11/18639	0.727272727272727	2.65069150638177	0.00229296862786799	0.0166606124769557
GO:0043522	leucine zipper domain binding	8/5114	11/18639	0.727272727272727	2.65069150638177	0.00229296862786799	0.0166606124769557
GO:0140537	transcription regulator activator activity	8/5114	11/18639	0.727272727272727	2.65069150638177	0.00229296862786799	0.0166606124769557
GO:0035401	histone H3Y41 kinase activity	46/5114	115/18639	0.4	1.45788032850997	0.00231808498850548	0.0166658110226236
GO:0140801	histone H2AXY142 kinase activity	46/5114	115/18639	0.4	1.45788032850997	0.00231808498850548	0.0166658110226236
GO:0015215	nucleotide transmembrane transporter activity	16/5114	30/18639	0.533333333333333	1.9438404380133	0.00237426517989963	0.0168043846411549
GO:0051721	protein phosphatase 2A binding	16/5114	30/18639	0.533333333333333	1.9438404380133	0.00237426517989963	0.0168043846411549
GO:0070566	adenylyltransferase activity	16/5114	30/18639	0.533333333333333	1.9438404380133	0.00237426517989963	0.0168043846411549
GO:0042974	nuclear retinoic acid receptor binding	14/5114	25/18639	0.56	2.04103245991396	0.00242057211878255	0.0170003414418192
GO:0000287	magnesium ion binding	83/5114	230/18639	0.360869565217391	1.31526160072095	0.00242684229952763	0.0170003414418192
GO:0043531	ADP binding	19/5114	38/18639	0.5	1.82235041063747	0.00256073182230287	0.0178467330064578
GO:0008135	translation factor activity, RNA binding	35/5114	83/18639	0.421686746987952	1.53692203306774	0.00264634744540915	0.0183498000529385
GO:0031490	chromatin DNA binding	50/5114	128/18639	0.390625	1.42371125831052	0.00276974334678481	0.0191084313722629
GO:0032393	MHC class I receptor activity	11/5114	18/18639	0.611111111111111	2.2273171685569	0.00281535246435	0.0191331913746373
GO:0052744	phosphatidylinositol monophosphate phosphatase activity	11/5114	18/18639	0.611111111111111	2.2273171685569	0.00281535246435	0.0191331913746373
GO:0070628	proteasome binding	11/5114	18/18639	0.611111111111111	2.2273171685569	0.00281535246435	0.0191331913746373
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	20/5114	41/18639	0.48780487804878	1.77790283964631	0.00289471886584004	0.0194787486243227
GO:0061650	ubiquitin-like protein conjugating enzyme activity	20/5114	41/18639	0.48780487804878	1.77790283964631	0.00289471886584004	0.0194787486243227
GO:0046966	nuclear thyroid hormone receptor binding	15/5114	28/18639	0.535714285714286	1.95251829711157	0.00305344437945253	0.0204461030506478
GO:0043274	phospholipase binding	13/5114	23/18639	0.565217391304348	2.06004829028583	0.00309216486155068	0.0205043553440691
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	13/5114	23/18639	0.565217391304348	2.06004829028583	0.00309216486155068	0.0205043553440691
GO:0005484	SNAP receptor activity	18/5114	36/18639	0.5	1.82235041063747	0.00329764292940367	0.02176125720563
GO:0180051	translation factor activity	35/5114	84/18639	0.416666666666667	1.51862534219789	0.00335688027146778	0.0220456656289663
GO:1990782	protein tyrosine kinase binding	46/5114	117/18639	0.393162393162393	1.43295929725339	0.00344841982076463	0.0225384759577248
GO:0022858	alanine transmembrane transporter activity	10/5114	16/18639	0.625	2.27793801329683	0.00349895236242454	0.0226519854363598
GO:0030275	LRR domain binding	10/5114	16/18639	0.625	2.27793801329683	0.00349895236242454	0.0226519854363598
GO:0051010	microtubule plus-end binding	12/5114	21/18639	0.571428571428571	2.08268618358568	0.00394854284313142	0.0254420260552713
GO:0140296	general transcription initiation factor binding	24/5114	53/18639	0.452830188679245	1.65043056057733	0.00400595886044288	0.0256907971988966
GO:0004540	RNA nuclease activity	47/5114	121/18639	0.388429752066116	1.41571023636299	0.00413411583943309	0.0262660569147237
GO:0051082	unfolded protein binding	47/5114	121/18639	0.388429752066116	1.41571023636299	0.00413411583943309	0.0262660569147237
GO:0052866	phosphatidylinositol phosphate phosphatase activity	17/5114	34/18639	0.5	1.82235041063747	0.00425177058628023	0.0268885121336055
GO:0032454	histone H3K9 demethylase activity	9/5114	14/18639	0.642857142857143	2.34302195653388	0.00430737309703425	0.0269902369291229
GO:0061665	SUMO ligase activity	9/5114	14/18639	0.642857142857143	2.34302195653388	0.00430737309703425	0.0269902369291229
GO:0004518	nuclease activity	75/5114	209/18639	0.358851674641148	1.30790699328048	0.00446159775343017	0.0278149816846575
GO:0140303	intramembrane lipid transporter activity	21/5114	45/18639	0.466666666666667	1.70086038326163	0.00447971886575744	0.0278149816846575
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	15/5114	29/18639	0.517241379310345	1.88519007996979	0.00473618651398102	0.0290117972112021
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	15/5114	29/18639	0.517241379310345	1.88519007996979	0.00473618651398102	0.0290117972112021
GO:0097472	cyclin-dependent protein kinase activity	15/5114	29/18639	0.517241379310345	1.88519007996979	0.00473618651398102	0.0290117972112021
GO:0140693	molecular condensate scaffold activity	22/5114	48/18639	0.458333333333333	1.67048787641768	0.0048073449102373	0.0293162194079649
GO:0030552	cAMP binding	13/5114	24/18639	0.541666666666667	1.97421294485725	0.00506593352826809	0.0306274712945079
GO:0030544	Hsp70 protein binding	23/5114	51/18639	0.450980392156863	1.64368860567301	0.00510111911826218	0.0306274712945079
GO:0008603	cAMP-dependent protein kinase regulator activity	8/5114	12/18639	0.666666666666667	2.42980054751662	0.00522415872007345	0.0306274712945079
GO:0035014	phosphatidylinositol 3-kinase regulator activity	8/5114	12/18639	0.666666666666667	2.42980054751662	0.00522415872007345	0.0306274712945079
GO:0035197	siRNA binding	8/5114	12/18639	0.666666666666667	2.42980054751662	0.00522415872007345	0.0306274712945079
GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	8/5114	12/18639	0.666666666666667	2.42980054751662	0.00522415872007345	0.0306274712945079
GO:0140822	NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity	8/5114	12/18639	0.666666666666667	2.42980054751662	0.00522415872007345	0.0306274712945079
GO:0140844	NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity	8/5114	12/18639	0.666666666666667	2.42980054751662	0.00522415872007345	0.0306274712945079
GO:0140867	NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity	8/5114	12/18639	0.666666666666667	2.42980054751662	0.00522415872007345	0.0306274712945079
GO:0050660	flavin adenine dinucleotide binding	35/5114	86/18639	0.406976744186047	1.48330847377468	0.0052732107122075	0.0307545406465084
GO:0140662	ATP-dependent protein folding chaperone	19/5114	40/18639	0.475	1.73123289010559	0.00529086167784003	0.0307545406465084
GO:0015932	nucleobase-containing compound transmembrane transporter activity	25/5114	57/18639	0.43859649122807	1.59855299178725	0.00559108106889508	0.032361935339452
GO:0030276	clathrin binding	21/5114	46/18639	0.456521739130435	1.66388515753856	0.00614178187938703	0.0353264630538755
GO:0031996	thioesterase binding	7/5114	10/18639	0.7	2.55129057489245	0.00618083797209095	0.0353264630538755
GO:0071723	lipopeptide binding	7/5114	10/18639	0.7	2.55129057489245	0.00618083797209095	0.0353264630538755
GO:0002039	p53 binding	29/5114	69/18639	0.420289855072464	1.53183077995613	0.00622607111058241	0.0354367214043982
GO:0004843	cysteine-type deubiquitinase activity	42/5114	108/18639	0.388888888888889	1.41738365271803	0.00630245837625133	0.0357226478919474
GO:0004438	phosphatidylinositol-3-phosphate phosphatase activity	10/5114	17/18639	0.588235294117647	2.14394165957349	0.0064196143414875	0.0362363354978179
GO:0016763	pentosyltransferase activity	22/5114	49/18639	0.448979591836735	1.63639628710303	0.00649708036369831	0.0365226822091024
GO:0140313	molecular sequestering activity	24/5114	55/18639	0.436363636363636	1.59041490382906	0.00707701413296809	0.0396196774821082
GO:0008408	3'-5' exonuclease activity	25/5114	58/18639	0.431034482758621	1.57099173330816	0.00730684937267791	0.0407394132370532
GO:0043014	alpha-tubulin binding	20/5114	44/18639	0.454545454545455	1.6566821914886	0.00785017644934471	0.0435908171943288
GO:0004709	MAP kinase kinase kinase activity	13/5114	25/18639	0.52	1.89524442706296	0.0079317417218774	0.0438654218303018
GO:0140034	methylation-dependent protein binding	31/5114	76/18639	0.407894736842105	1.48665428236214	0.00801825335211536	0.0441650567701193
GO:0042809	nuclear vitamin D receptor binding	9/5114	15/18639	0.6	2.18682049276496	0.00816031886894543	0.0447670505019255
GO:0030742	GTP-dependent protein binding	11/5114	20/18639	0.55	2.00458545170121	0.00844476117852474	0.0459583417126087
GO:0042288	MHC class I protein binding	11/5114	20/18639	0.55	2.00458545170121	0.00844476117852474	0.0459583417126087
GO:0015605	organophosphate ester transmembrane transporter activity	22/5114	50/18639	0.44	1.60366836136097	0.00864415330688976	0.0468567992746485
GO:0016791	phosphatase activity	93/5114	273/18639	0.340659340659341	1.24160137867608	0.00906902490883832	0.0489655653180756
GO:0046875	ephrin receptor binding	14/5114	28/18639	0.5	1.82235041063747	0.00919413337272897	0.0492517105378344
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	14/5114	28/18639	0.5	1.82235041063747	0.00919413337272897	0.0492517105378344
GO:0003684	damaged DNA binding	30/5114	74/18639	0.405405405405405	1.47758141403038	0.009944671297255	0.0528576692297678
GO:0035064	methylated histone binding	30/5114	74/18639	0.405405405405405	1.47758141403038	0.009944671297255	0.0528576692297678
GO:0019894	kinesin binding	19/5114	42/18639	0.452380952380952	1.64879322867199	0.0100385851403729	0.0529448158368703
GO:0048487	beta-tubulin binding	19/5114	42/18639	0.452380952380952	1.64879322867199	0.0100385851403729	0.0529448158368703
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	12/5114	23/18639	0.521739130434783	1.90158303718692	0.0102939832660217	0.0532514878443814
GO:0005158	insulin receptor binding	12/5114	23/18639	0.521739130434783	1.90158303718692	0.0102939832660217	0.0532514878443814
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	12/5114	23/18639	0.521739130434783	1.90158303718692	0.0102939832660217	0.0532514878443814
GO:0051011	microtubule minus-end binding	8/5114	13/18639	0.615384615384615	2.24289281309227	0.0103306327077314	0.0532514878443814
GO:0140666	annealing activity	8/5114	13/18639	0.615384615384615	2.24289281309227	0.0103306327077314	0.0532514878443814
GO:0140852	histone ubiquitin ligase activity	8/5114	13/18639	0.615384615384615	2.24289281309227	0.0103306327077314	0.0532514878443814
GO:0046915	transition metal ion transmembrane transporter activity	20/5114	45/18639	0.444444444444444	1.61986703167775	0.0105465425162146	0.0541600641998086
GO:0004706	JUN kinase kinase kinase activity	10/5114	18/18639	0.555555555555556	2.02483378959718	0.0109249416879094	0.0558931473621131
GO:0004896	cytokine receptor activity	37/5114	96/18639	0.385416666666667	1.40472844153305	0.0116310175293036	0.0590630852975044
GO:0016407	acetyltransferase activity	37/5114	96/18639	0.385416666666667	1.40472844153305	0.0116310175293036	0.0590630852975044
GO:0005112	Notch binding	13/5114	26/18639	0.5	1.82235041063747	0.0119326246512113	0.0597068325038632
GO:0008157	protein phosphatase 1 binding	13/5114	26/18639	0.5	1.82235041063747	0.0119326246512113	0.0597068325038632
GO:0050681	nuclear androgen receptor binding	13/5114	26/18639	0.5	1.82235041063747	0.0119326246512113	0.0597068325038632
GO:0070412	R-SMAD binding	13/5114	26/18639	0.5	1.82235041063747	0.0119326246512113	0.0597068325038632
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	25/5114	60/18639	0.416666666666667	1.51862534219789	0.0120334650353795	0.0599916541544834
GO:0051117	ATPase binding	33/5114	84/18639	0.392857142857143	1.43184675121515	0.012122056949869	0.0602135628855311
GO:0015101	organic cation transmembrane transporter activity	32/5114	81/18639	0.395061728395062	1.43988180593578	0.0122052668672916	0.0604072265968129
GO:0008432	JUN kinase binding	7/5114	11/18639	0.636363636363636	2.31935506808405	0.0129846093244811	0.0635733918897536
GO:0015173	aromatic amino acid transmembrane transporter activity	7/5114	11/18639	0.636363636363636	2.31935506808405	0.0129846093244811	0.0635733918897536
GO:0180030	inositol phosphate kinase activity	7/5114	11/18639	0.636363636363636	2.31935506808405	0.0129846093244811	0.0635733918897536
GO:0004722	protein serine/threonine phosphatase activity	39/5114	103/18639	0.378640776699029	1.38003234980313	0.0134878939292436	0.0658016539548097
GO:0030291	protein serine/threonine kinase inhibitor activity	20/5114	46/18639	0.434782608695652	1.5846525309891	0.0139348199291589	0.0677400854919253
GO:0140327	flippase activity	9/5114	16/18639	0.5625	2.05014421196715	0.0141535043773295	0.0685591736859292
GO:0120015	sterol transfer activity	15/5114	32/18639	0.46875	1.70845350997262	0.0145695713625085	0.0703252101808716
GO:0030159	signaling receptor complex adaptor activity	22/5114	52/18639	0.423076923076923	1.54198880900093	0.0146495519565266	0.0704622815937158
GO:0051015	actin filament binding	72/5114	209/18639	0.344497607655502	1.25559071354926	0.0150597267672564	0.0721810061897272
GO:0097110	scaffold protein binding	28/5114	70/18639	0.4	1.45788032850997	0.0152454533051867	0.0728156965555421
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	12/5114	24/18639	0.5	1.82235041063747	0.0155220330037753	0.0736218648720732
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	12/5114	24/18639	0.5	1.82235041063747	0.0155220330037753	0.0736218648720732
GO:0005126	cytokine receptor binding	92/5114	275/18639	0.334545454545455	1.21931809293561	0.0157040057975934	0.0742272384758219
GO:0042162	telomeric DNA binding	17/5114	38/18639	0.447368421052632	1.630524051623	0.0164412303593865	0.0774438643824895
GO:0042287	MHC protein binding	18/5114	41/18639	0.439024390243902	1.60011255568168	0.0171348913653957	0.0804338886774246
GO:0034593	phosphatidylinositol bisphosphate phosphatase activity	13/5114	27/18639	0.481481481481481	1.75485595098423	0.0173265435852518	0.0810549949912808
GO:1902936	phosphatidylinositol bisphosphate binding	41/5114	111/18639	0.369369369369369	1.34624084389434	0.0180433532864498	0.0839320977265609
GO:0061733	protein-lysine-acetyltransferase activity	20/5114	47/18639	0.425531914893617	1.55093651969146	0.0181258922615926	0.0839320977265609
GO:1990518	single-stranded 3'-5' DNA helicase activity	20/5114	47/18639	0.425531914893617	1.55093651969146	0.0181258922615926	0.0839320977265609
GO:0005161	platelet-derived growth factor receptor binding	8/5114	14/18639	0.571428571428571	2.08268618358568	0.0183616455219942	0.0841678113524971
GO:0005545	1-phosphatidylinositol binding	8/5114	14/18639	0.571428571428571	2.08268618358568	0.0183616455219942	0.0841678113524971
GO:0046030	inositol trisphosphate phosphatase activity	8/5114	14/18639	0.571428571428571	2.08268618358568	0.0183616455219942	0.0841678113524971
GO:0030246	carbohydrate binding	93/5114	280/18639	0.332142857142857	1.21056134420917	0.0185270799235366	0.0846421109550202
GO:0051018	protein kinase A binding	22/5114	53/18639	0.415094339622642	1.51289468052922	0.0186899727076122	0.0848883916215923
GO:0001968	fibronectin binding	14/5114	30/18639	0.466666666666667	1.70086038326163	0.0188295627096211	0.0848883916215923
GO:0031624	ubiquitin conjugating enzyme binding	14/5114	30/18639	0.466666666666667	1.70086038326163	0.0188295627096211	0.0848883916215923
GO:0035925	mRNA 3'-UTR AU-rich region binding	14/5114	30/18639	0.466666666666667	1.70086038326163	0.0188295627096211	0.0848883916215923
GO:0140311	protein sequestering activity	15/5114	33/18639	0.454545454545455	1.6566821914886	0.0200627972550509	0.0901505955605247
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	17/5114	39/18639	0.435897435897436	1.58871574260702	0.0218475153139373	0.0978482161273387
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	77/5114	229/18639	0.336244541484716	1.22551075649856	0.0223936444095862	0.0999663995539046
GO:0046965	nuclear retinoid X receptor binding	9/5114	17/18639	0.529411764705882	1.92954749361614	0.0228541306676516	0.100751785886998
GO:0070403	NAD+ binding	9/5114	17/18639	0.529411764705882	1.92954749361614	0.0228541306676516	0.100751785886998
GO:1990226	histone methyltransferase binding	9/5114	17/18639	0.529411764705882	1.92954749361614	0.0228541306676516	0.100751785886998
GO:0008080	N-acetyltransferase activity	27/5114	69/18639	0.391304347826087	1.42618727789019	0.0230430427372562	0.100751785886998
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	20/5114	48/18639	0.416666666666667	1.51862534219789	0.023233391328261	0.100751785886998
GO:0032266	phosphatidylinositol-3-phosphate binding	20/5114	48/18639	0.416666666666667	1.51862534219789	0.023233391328261	0.100751785886998
GO:0036121	double-stranded DNA helicase activity	20/5114	48/18639	0.416666666666667	1.51862534219789	0.023233391328261	0.100751785886998
GO:0038187	pattern recognition receptor activity	20/5114	48/18639	0.416666666666667	1.51862534219789	0.023233391328261	0.100751785886998
GO:0043138	3'-5' DNA helicase activity	20/5114	48/18639	0.416666666666667	1.51862534219789	0.023233391328261	0.100751785886998
GO:0003743	translation initiation factor activity	21/5114	51/18639	0.411764705882353	1.50075916170144	0.0234401933931637	0.100860873291364
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	22/5114	54/18639	0.407407407407407	1.48487811237127	0.0235485292044425	0.100860873291364
GO:0005078	MAP-kinase scaffold activity	7/5114	12/18639	0.583333333333333	2.12607547907704	0.0238492401706519	0.100860873291364
GO:0005095	GTPase inhibitor activity	7/5114	12/18639	0.583333333333333	2.12607547907704	0.0238492401706519	0.100860873291364
GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity	7/5114	12/18639	0.583333333333333	2.12607547907704	0.0238492401706519	0.100860873291364
GO:0070008	serine-type exopeptidase activity	7/5114	12/18639	0.583333333333333	2.12607547907704	0.0238492401706519	0.100860873291364
GO:0097677	STAT family protein binding	7/5114	12/18639	0.583333333333333	2.12607547907704	0.0238492401706519	0.100860873291364
GO:1990817	poly(A) RNA polymerase activity	7/5114	12/18639	0.583333333333333	2.12607547907704	0.0238492401706519	0.100860873291364
GO:0019789	SUMO transferase activity	13/5114	28/18639	0.464285714285714	1.69218252416336	0.0243746324361049	0.102448455100675
GO:0051959	dynein light intermediate chain binding	13/5114	28/18639	0.464285714285714	1.69218252416336	0.0243746324361049	0.102448455100675
GO:0072349	modified amino acid transmembrane transporter activity	14/5114	31/18639	0.451612903225806	1.64599391928545	0.0258430038091116	0.108286942341247
GO:0061608	nuclear import signal receptor activity	10/5114	20/18639	0.5	1.82235041063747	0.0264868062618628	0.110645190684112
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	46/5114	130/18639	0.353846153846154	1.28966336752805	0.0283899326357129	0.118233682867024
GO:0015036	disulfide oxidoreductase activity	17/5114	40/18639	0.425	1.54899784904185	0.0285025914334105	0.118342066559388
GO:0048156	tau protein binding	18/5114	43/18639	0.418604651162791	1.52568871588253	0.0289483352210469	0.119828563369546
GO:0017116	single-stranded DNA helicase activity	23/5114	58/18639	0.396551724137931	1.44531239464351	0.0291629168730744	0.120352098032084
GO:0003887	DNA-directed DNA polymerase activity	11/5114	23/18639	0.478260869565217	1.74311778408801	0.0293661709826631	0.120825872175656
GO:0000774	adenyl-nucleotide exchange factor activity	8/5114	15/18639	0.533333333333333	1.9438404380133	0.03002030455405	0.122411152300992
GO:0047372	monoacylglycerol lipase activity	8/5114	15/18639	0.533333333333333	1.9438404380133	0.03002030455405	0.122411152300992
GO:0120283	protein serine/threonine kinase binding	8/5114	15/18639	0.533333333333333	1.9438404380133	0.03002030455405	0.122411152300992
GO:0004445	inositol-polyphosphate 5-phosphatase activity	6/5114	10/18639	0.6	2.18682049276496	0.0309943572602031	0.123313074031584
GO:0004862	cAMP-dependent protein kinase inhibitor activity	6/5114	10/18639	0.6	2.18682049276496	0.0309943572602031	0.123313074031584
GO:0008140	cAMP response element binding protein binding	6/5114	10/18639	0.6	2.18682049276496	0.0309943572602031	0.123313074031584
GO:0016427	tRNA (cytidine) methyltransferase activity	6/5114	10/18639	0.6	2.18682049276496	0.0309943572602031	0.123313074031584
GO:0042975	peroxisome proliferator activated receptor binding	6/5114	10/18639	0.6	2.18682049276496	0.0309943572602031	0.123313074031584
GO:0043422	protein kinase B binding	6/5114	10/18639	0.6	2.18682049276496	0.0309943572602031	0.123313074031584
GO:0051864	histone H3K36 demethylase activity	6/5114	10/18639	0.6	2.18682049276496	0.0309943572602031	0.123313074031584
GO:0099122	RNA polymerase II C-terminal domain binding	6/5114	10/18639	0.6	2.18682049276496	0.0309943572602031	0.123313074031584
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	31/5114	83/18639	0.373493975903614	1.36127380071714	0.0310539512934589	0.123313074031584
GO:0004112	cyclic-nucleotide phosphodiesterase activity	12/5114	26/18639	0.461538461538462	1.6821696098192	0.0316105966463692	0.124438256538733
GO:0015216	purine nucleotide transmembrane transporter activity	12/5114	26/18639	0.461538461538462	1.6821696098192	0.0316105966463692	0.124438256538733
GO:0019865	immunoglobulin binding	12/5114	26/18639	0.461538461538462	1.6821696098192	0.0316105966463692	0.124438256538733
GO:0003678	DNA helicase activity	28/5114	74/18639	0.378378378378378	1.37907598642835	0.0329842540327721	0.129472675312548
GO:0010484	histone H3 acetyltransferase activity	13/5114	29/18639	0.448275862068966	1.63383140264049	0.0333281782238807	0.130219977121241
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	45/5114	128/18639	0.3515625	1.28134013247947	0.033365294284359	0.130219977121241
GO:0043022	ribosome binding	40/5114	112/18639	0.357142857142857	1.30167886474105	0.0336234276827779	0.130853567563175
GO:0051213	dioxygenase activity	34/5114	93/18639	0.365591397849462	1.33247126799299	0.034034719930589	0.131983373995389
GO:0005548	phospholipid transporter activity	26/5114	68/18639	0.382352941176471	1.39356207872277	0.0341793149701465	0.131983373995389
GO:0022884	macromolecule transmembrane transporter activity	14/5114	32/18639	0.4375	1.59455660930778	0.0346112290453587	0.131983373995389
GO:0051059	NF-kappaB binding	14/5114	32/18639	0.4375	1.59455660930778	0.0346112290453587	0.131983373995389
GO:0038024	cargo receptor activity	25/5114	65/18639	0.384615384615385	1.40180800818267	0.0347312222915678	0.131983373995389
GO:0008409	5'-3' exonuclease activity	9/5114	18/18639	0.5	1.82235041063747	0.034783319647394	0.131983373995389
GO:0008525	phosphatidylcholine transporter activity	9/5114	18/18639	0.5	1.82235041063747	0.034783319647394	0.131983373995389
GO:0030228	lipoprotein particle receptor activity	9/5114	18/18639	0.5	1.82235041063747	0.034783319647394	0.131983373995389
GO:1990381	ubiquitin-specific protease binding	9/5114	18/18639	0.5	1.82235041063747	0.034783319647394	0.131983373995389
GO:0015291	secondary active transmembrane transporter activity	93/5114	287/18639	0.32404181184669	1.18103545776505	0.0348952237806217	0.132041206881799
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	151/5114	484/18639	0.31198347107438	1.137086413249	0.035024773611905	0.132165305949896
GO:0005516	calmodulin binding	69/5114	207/18639	0.333333333333333	1.21490027375831	0.0351839485915528	0.132269321657286
GO:0005154	epidermal growth factor receptor binding	15/5114	35/18639	0.428571428571429	1.56201463768926	0.0355364868581435	0.132269321657286
GO:0010485	histone H4 acetyltransferase activity	15/5114	35/18639	0.428571428571429	1.56201463768926	0.0355364868581435	0.132269321657286
GO:0043015	gamma-tubulin binding	15/5114	35/18639	0.428571428571429	1.56201463768926	0.0355364868581435	0.132269321657286
GO:0140566	histone reader activity	15/5114	35/18639	0.428571428571429	1.56201463768926	0.0355364868581435	0.132269321657286
GO:1901505	carbohydrate derivative transmembrane transporter activity	21/5114	53/18639	0.39622641509434	1.44412674050516	0.036420412733155	0.135190988569266
GO:0140318	protein transporter activity	17/5114	41/18639	0.414634146341463	1.51121741369936	0.0365547123149211	0.135321780547919
GO:0043495	protein-membrane adaptor activity	19/5114	47/18639	0.404255319148936	1.47338969370689	0.0367635022022204	0.135361035062623
GO:0061749	forked DNA-dependent helicase activity	19/5114	47/18639	0.404255319148936	1.47338969370689	0.0367635022022204	0.135361035062623
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	10/5114	21/18639	0.476190476190476	1.73557181965473	0.0383924470931405	0.139478943428803
GO:0019200	carbohydrate kinase activity	10/5114	21/18639	0.476190476190476	1.73557181965473	0.0383924470931405	0.139478943428803
GO:0035613	RNA stem-loop binding	10/5114	21/18639	0.476190476190476	1.73557181965473	0.0383924470931405	0.139478943428803
GO:0070182	DNA polymerase binding	10/5114	21/18639	0.476190476190476	1.73557181965473	0.0383924470931405	0.139478943428803
GO:0072542	protein phosphatase activator activity	10/5114	21/18639	0.476190476190476	1.73557181965473	0.0383924470931405	0.139478943428803
GO:0004721	phosphoprotein phosphatase activity	59/5114	175/18639	0.337142857142857	1.22878484831555	0.0391435745466339	0.141681194153189
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	7/5114	13/18639	0.538461538461538	1.96253121145573	0.0396209488773926	0.141681194153189
GO:0005035	death receptor activity	7/5114	13/18639	0.538461538461538	1.96253121145573	0.0396209488773926	0.141681194153189
GO:0008035	high-density lipoprotein particle binding	7/5114	13/18639	0.538461538461538	1.96253121145573	0.0396209488773926	0.141681194153189
GO:0035325	Toll-like receptor binding	7/5114	13/18639	0.538461538461538	1.96253121145573	0.0396209488773926	0.141681194153189
GO:0140333	glycerophospholipid flippase activity	7/5114	13/18639	0.538461538461538	1.96253121145573	0.0396209488773926	0.141681194153189
GO:0035035	histone acetyltransferase binding	11/5114	24/18639	0.458333333333333	1.67048787641768	0.0410804415801836	0.145755540775405
GO:0050699	WW domain binding	11/5114	24/18639	0.458333333333333	1.67048787641768	0.0410804415801836	0.145755540775405
GO:0070300	phosphatidic acid binding	11/5114	24/18639	0.458333333333333	1.67048787641768	0.0410804415801836	0.145755540775405
GO:1901682	sulfur compound transmembrane transporter activity	24/5114	63/18639	0.380952380952381	1.38845745572378	0.0425210221658493	0.150475948908161
GO:0008320	protein transmembrane transporter activity	12/5114	27/18639	0.444444444444444	1.61986703167775	0.0430378390952633	0.151911339028759
GO:0001216	DNA-binding transcription activator activity	152/5114	491/18639	0.309572301425662	1.12829842125008	0.0438984105541253	0.154549558806534
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	30/5114	82/18639	0.365853658536585	1.33342712973473	0.0440206324745905	0.154581449769385
GO:0008187	poly-pyrimidine tract binding	13/5114	30/18639	0.433333333333333	1.5793703558858	0.0444153547936087	0.155567627302742
GO:0015485	cholesterol binding	21/5114	54/18639	0.388888888888889	1.41738365271803	0.0446116113423354	0.155855399216445
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	14/5114	33/18639	0.424242424242424	1.54623671205603	0.0453311261540065	0.157491922266916
GO:0009378	four-way junction helicase activity	19/5114	48/18639	0.395833333333333	1.44269407508799	0.0456280576024008	0.157491922266916
GO:0044390	ubiquitin-like protein conjugating enzyme binding	15/5114	36/18639	0.416666666666667	1.51862534219789	0.0458778236040203	0.157491922266916
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	8/5114	16/18639	0.5	1.82235041063747	0.0458871047307705	0.157491922266916
GO:0034450	ubiquitin-ubiquitin ligase activity	8/5114	16/18639	0.5	1.82235041063747	0.0458871047307705	0.157491922266916
GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	8/5114	16/18639	0.5	1.82235041063747	0.0458871047307705	0.157491922266916
GO:0106018	phosphatidylinositol-3,5-bisphosphate phosphatase activity	8/5114	16/18639	0.5	1.82235041063747	0.0458871047307705	0.157491922266916
GO:0004402	histone acetyltransferase activity	17/5114	42/18639	0.404761904761905	1.47523604670652	0.0461410743858368	0.157966685741988
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	9/5114	19/18639	0.473684210526316	1.72643723113023	0.050369101981874	0.171154709719502
GO:0140036	ubiquitin-modified protein reader activity	9/5114	19/18639	0.473684210526316	1.72643723113023	0.050369101981874	0.171154709719502
GO:1990380	K48-linked deubiquitinase activity	9/5114	19/18639	0.473684210526316	1.72643723113023	0.050369101981874	0.171154709719502
GO:0003953	NAD+ nucleosidase activity	6/5114	11/18639	0.545454545454545	1.98801862978633	0.0526060547830695	0.176559879198214
GO:0005536	D-glucose binding	6/5114	11/18639	0.545454545454545	1.98801862978633	0.0526060547830695	0.176559879198214
GO:0032050	clathrin heavy chain binding	6/5114	11/18639	0.545454545454545	1.98801862978633	0.0526060547830695	0.176559879198214
GO:0042608	T cell receptor binding	6/5114	11/18639	0.545454545454545	1.98801862978633	0.0526060547830695	0.176559879198214
GO:0140031	phosphorylation-dependent protein binding	6/5114	11/18639	0.545454545454545	1.98801862978633	0.0526060547830695	0.176559879198214
GO:0004407	histone deacetylase activity	10/5114	22/18639	0.454545454545455	1.6566821914886	0.0535155780867649	0.177432717637186
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	10/5114	22/18639	0.454545454545455	1.6566821914886	0.0535155780867649	0.177432717637186
GO:0033558	protein lysine deacetylase activity	10/5114	22/18639	0.454545454545455	1.6566821914886	0.0535155780867649	0.177432717637186
GO:0033691	sialic acid binding	10/5114	22/18639	0.454545454545455	1.6566821914886	0.0535155780867649	0.177432717637186
GO:0050321	tau-protein kinase activity	10/5114	22/18639	0.454545454545455	1.6566821914886	0.0535155780867649	0.177432717637186
GO:0008483	transaminase activity	11/5114	25/18639	0.44	1.60366836136097	0.0556570018945563	0.183198709850516
GO:0019211	phosphatase activator activity	11/5114	25/18639	0.44	1.60366836136097	0.0556570018945563	0.183198709850516
GO:0120020	cholesterol transfer activity	11/5114	25/18639	0.44	1.60366836136097	0.0556570018945563	0.183198709850516
GO:0036408	histone H3K14 acetyltransferase activity	12/5114	28/18639	0.428571428571429	1.56201463768926	0.0570352440896322	0.186387902934061
GO:0050698	proteoglycan sulfotransferase activity	12/5114	28/18639	0.428571428571429	1.56201463768926	0.0570352440896322	0.186387902934061
GO:0097718	disordered domain specific binding	12/5114	28/18639	0.428571428571429	1.56201463768926	0.0570352440896322	0.186387902934061
GO:0008375	acetylglucosaminyltransferase activity	17/5114	43/18639	0.395348837209302	1.44092823166683	0.0573824807628149	0.187075104348461
GO:0008081	phosphoric diester hydrolase activity	31/5114	87/18639	0.35632183908046	1.29868649953475	0.0578129746330421	0.187352698350318
GO:0016411	acylglycerol O-acyltransferase activity	13/5114	31/18639	0.419354838709677	1.52842292505078	0.0578287193935233	0.187352698350318
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	16/5114	40/18639	0.4	1.45788032850997	0.0578790912912401	0.187352698350318
GO:0030551	cyclic nucleotide binding	15/5114	37/18639	0.405405405405405	1.47758141403038	0.058161714303437	0.187408213506775
GO:0030332	cyclin binding	14/5114	34/18639	0.411764705882353	1.50075916170144	0.0581706314252363	0.187408213506775
GO:0030145	manganese ion binding	25/5114	68/18639	0.367647058823529	1.33996353723343	0.0587517146400327	0.188391648352781
GO:0032934	sterol binding	25/5114	68/18639	0.367647058823529	1.33996353723343	0.0587517146400327	0.188391648352781
GO:0120013	lipid transfer activity	24/5114	65/18639	0.369230769230769	1.34573568785536	0.0602759212206215	0.189978893198009
GO:0008559	ABC-type xenobiotic transporter activity	7/5114	14/18639	0.5	1.82235041063747	0.0608802522327908	0.189978893198009
GO:0019763	immunoglobulin receptor activity	7/5114	14/18639	0.5	1.82235041063747	0.0608802522327908	0.189978893198009
GO:0030983	mismatched DNA binding	7/5114	14/18639	0.5	1.82235041063747	0.0608802522327908	0.189978893198009
GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity	7/5114	14/18639	0.5	1.82235041063747	0.0608802522327908	0.189978893198009
GO:0044548	S100 protein binding	7/5114	14/18639	0.5	1.82235041063747	0.0608802522327908	0.189978893198009
GO:0052816	long-chain fatty acyl-CoA hydrolase activity	7/5114	14/18639	0.5	1.82235041063747	0.0608802522327908	0.189978893198009
GO:0033192	calmodulin-dependent protein phosphatase activity	29/5114	81/18639	0.358024691358025	1.3048928866293	0.061332863763047	0.189978893198009
GO:0140791	histone H2AXS140 phosphatase activity	29/5114	81/18639	0.358024691358025	1.3048928866293	0.061332863763047	0.189978893198009
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	29/5114	81/18639	0.358024691358025	1.3048928866293	0.061332863763047	0.189978893198009
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	29/5114	81/18639	0.358024691358025	1.3048928866293	0.061332863763047	0.189978893198009
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	29/5114	81/18639	0.358024691358025	1.3048928866293	0.061332863763047	0.189978893198009
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	29/5114	81/18639	0.358024691358025	1.3048928866293	0.061332863763047	0.189978893198009
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	29/5114	81/18639	0.358024691358025	1.3048928866293	0.061332863763047	0.189978893198009
GO:1990439	MAP kinase serine/threonine phosphatase activity	29/5114	81/18639	0.358024691358025	1.3048928866293	0.061332863763047	0.189978893198009
GO:0015179	L-amino acid transmembrane transporter activity	23/5114	62/18639	0.370967741935484	1.35206643369876	0.0618028843797306	0.191001674350027
GO:0016410	N-acyltransferase activity	33/5114	94/18639	0.351063829787234	1.27952262874545	0.0624986957222525	0.19271606852505
GO:0034212	protein N-acetyltransferase activity	20/5114	53/18639	0.377358490566038	1.37535880048111	0.0663068707917004	0.201442075585644
GO:0004659	prenyltransferase activity	8/5114	17/18639	0.470588235294118	1.71515332765879	0.0663608594535429	0.201442075585644
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	8/5114	17/18639	0.470588235294118	1.71515332765879	0.0663608594535429	0.201442075585644
GO:0008484	sulfuric ester hydrolase activity	8/5114	17/18639	0.470588235294118	1.71515332765879	0.0663608594535429	0.201442075585644
GO:0030169	low-density lipoprotein particle binding	8/5114	17/18639	0.470588235294118	1.71515332765879	0.0663608594535429	0.201442075585644
GO:0032183	SUMO binding	8/5114	17/18639	0.470588235294118	1.71515332765879	0.0663608594535429	0.201442075585644
GO:0051787	misfolded protein binding	8/5114	17/18639	0.470588235294118	1.71515332765879	0.0663608594535429	0.201442075585644
GO:0000339	RNA cap binding	9/5114	20/18639	0.45	1.64011536957372	0.0699091621164285	0.211274149227967
GO:0043024	ribosomal small subunit binding	9/5114	20/18639	0.45	1.64011536957372	0.0699091621164285	0.211274149227967
GO:0001223	transcription coactivator binding	17/5114	44/18639	0.386363636363636	1.40817986276531	0.070378411829953	0.212222760617474
GO:0033549	MAP kinase phosphatase activity	29/5114	82/18639	0.353658536585366	1.28897955874357	0.0708055940906928	0.213040620105477
GO:0000295	adenine nucleotide transmembrane transporter activity	10/5114	23/18639	0.434782608695652	1.5846525309891	0.0720920450899203	0.215487382041206
GO:0042171	lysophosphatidic acid acyltransferase activity	10/5114	23/18639	0.434782608695652	1.5846525309891	0.0720920450899203	0.215487382041206
GO:0071617	lysophospholipid acyltransferase activity	10/5114	23/18639	0.434782608695652	1.5846525309891	0.0720920450899203	0.215487382041206
GO:0030247	polysaccharide binding	11/5114	26/18639	0.423076923076923	1.54198880900093	0.0732910324098934	0.217644347849172
GO:0070717	poly-purine tract binding	13/5114	32/18639	0.40625	1.48065970864294	0.0737143706843726	0.217644347849172
GO:0071813	lipoprotein particle binding	13/5114	32/18639	0.40625	1.48065970864294	0.0737143706843726	0.217644347849172
GO:0071814	protein-lipid complex binding	13/5114	32/18639	0.40625	1.48065970864294	0.0737143706843726	0.217644347849172
GO:0140142	nucleocytoplasmic carrier activity	13/5114	32/18639	0.40625	1.48065970864294	0.0737143706843726	0.217644347849172
GO:0051861	glycolipid binding	12/5114	29/18639	0.413793103448276	1.50815206397583	0.0737696435242802	0.217644347849172
GO:0098531	ligand-modulated transcription factor activity	22/5114	60/18639	0.366666666666667	1.33639030113414	0.0749335342464719	0.220601740906639
GO:0015297	antiporter activity	45/5114	135/18639	0.333333333333333	1.21490027375831	0.0762703096625442	0.224054286019431
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	30/5114	86/18639	0.348837209302326	1.27140726323544	0.0786397043907961	0.230518961797913
GO:0000340	RNA 7-methylguanosine cap binding	6/5114	12/18639	0.5	1.82235041063747	0.0813628693954871	0.236471658711139
GO:0005247	voltage-gated chloride channel activity	6/5114	12/18639	0.5	1.82235041063747	0.0813628693954871	0.236471658711139
GO:0031543	peptidyl-proline dioxygenase activity	6/5114	12/18639	0.5	1.82235041063747	0.0813628693954871	0.236471658711139
GO:1990247	N6-methyladenosine-containing RNA reader activity	6/5114	12/18639	0.5	1.82235041063747	0.0813628693954871	0.236471658711139
GO:0008173	RNA methyltransferase activity	24/5114	67/18639	0.358208955223881	1.30556447329251	0.0826801998727121	0.239790133813428
GO:0004857	enzyme inhibitor activity	127/5114	416/18639	0.305288461538462	1.11268510649499	0.0857814489878983	0.248257329062435
GO:0008307	structural constituent of muscle	16/5114	42/18639	0.380952380952381	1.38845745572378	0.0871486134977751	0.25168077386461
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	7/5114	15/18639	0.466666666666667	1.70086038326163	0.0878827064516892	0.252732162132647
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	7/5114	15/18639	0.466666666666667	1.70086038326163	0.0878827064516892	0.252732162132647
GO:0016798	hydrolase activity, acting on glycosyl bonds	43/5114	130/18639	0.330769230769231	1.20555488703709	0.0905739473645496	0.259924395168014
GO:0008308	voltage-gated monoatomic anion channel activity	8/5114	18/18639	0.444444444444444	1.61986703167775	0.0916228912984621	0.26183445504958
GO:0017075	syntaxin-1 binding	8/5114	18/18639	0.444444444444444	1.61986703167775	0.0916228912984621	0.26183445504958
GO:0140416	transcription regulator inhibitor activity	13/5114	33/18639	0.393939393939394	1.43579123262346	0.0921634796291108	0.262191849613419
GO:0017018	myosin phosphatase activity	29/5114	84/18639	0.345238095238095	1.25828956924968	0.0926891002783721	0.262191849613419
GO:0043995	histone H4K5 acetyltransferase activity	12/5114	30/18639	0.4	1.45788032850997	0.0933391693447277	0.262191849613419
GO:0043996	histone H4K8 acetyltransferase activity	12/5114	30/18639	0.4	1.45788032850997	0.0933391693447277	0.262191849613419
GO:0043997	histone H4K12 acetyltransferase activity	12/5114	30/18639	0.4	1.45788032850997	0.0933391693447277	0.262191849613419
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	9/5114	21/18639	0.428571428571429	1.56201463768926	0.0935466983838948	0.262191849613419
GO:0009931	calcium-dependent protein serine/threonine kinase activity	9/5114	21/18639	0.428571428571429	1.56201463768926	0.0935466983838948	0.262191849613419
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	9/5114	21/18639	0.428571428571429	1.56201463768926	0.0935466983838948	0.262191849613419
GO:0005385	zinc ion transmembrane transporter activity	11/5114	27/18639	0.407407407407407	1.48487811237127	0.0940901028137018	0.262191849613419
GO:0008266	poly(U) RNA binding	11/5114	27/18639	0.407407407407407	1.48487811237127	0.0940901028137018	0.262191849613419
GO:0001091	RNA polymerase II general transcription initiation factor binding	10/5114	24/18639	0.416666666666667	1.51862534219789	0.0942431904540179	0.262191849613419
GO:0048027	mRNA 5'-UTR binding	10/5114	24/18639	0.416666666666667	1.51862534219789	0.0942431904540179	0.262191849613419
GO:0070840	dynein complex binding	10/5114	24/18639	0.416666666666667	1.51862534219789	0.0942431904540179	0.262191849613419
GO:0030971	receptor tyrosine kinase binding	28/5114	81/18639	0.345679012345679	1.2598965801938	0.0958973406447721	0.266251559595038
GO:0005080	protein kinase C binding	19/5114	52/18639	0.365384615384615	1.33171760777353	0.0961717469837417	0.266471818214587
GO:0004879	nuclear receptor activity	21/5114	59/18639	0.355932203389831	1.29726639401311	0.105676302548992	0.292214229315634
GO:0004382	GDP phosphatase activity	5/5114	10/18639	0.5	1.82235041063747	0.109797315403377	0.294662343499044
GO:0004955	prostaglandin receptor activity	5/5114	10/18639	0.5	1.82235041063747	0.109797315403377	0.294662343499044
GO:0005031	tumor necrosis factor receptor activity	5/5114	10/18639	0.5	1.82235041063747	0.109797315403377	0.294662343499044
GO:0005381	iron ion transmembrane transporter activity	5/5114	10/18639	0.5	1.82235041063747	0.109797315403377	0.294662343499044
GO:0008190	eukaryotic initiation factor 4E binding	5/5114	10/18639	0.5	1.82235041063747	0.109797315403377	0.294662343499044
GO:0015658	branched-chain amino acid transmembrane transporter activity	5/5114	10/18639	0.5	1.82235041063747	0.109797315403377	0.294662343499044
GO:0016303	1-phosphatidylinositol-3-kinase activity	5/5114	10/18639	0.5	1.82235041063747	0.109797315403377	0.294662343499044
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	5/5114	10/18639	0.5	1.82235041063747	0.109797315403377	0.294662343499044
GO:0030957	Tat protein binding	5/5114	10/18639	0.5	1.82235041063747	0.109797315403377	0.294662343499044
GO:0031419	cobalamin binding	5/5114	10/18639	0.5	1.82235041063747	0.109797315403377	0.294662343499044
GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity	5/5114	10/18639	0.5	1.82235041063747	0.109797315403377	0.294662343499044
GO:0035256	G protein-coupled glutamate receptor binding	5/5114	10/18639	0.5	1.82235041063747	0.109797315403377	0.294662343499044
GO:0036435	K48-linked polyubiquitin modification-dependent protein binding	5/5114	10/18639	0.5	1.82235041063747	0.109797315403377	0.294662343499044
GO:0043225	ATPase-coupled inorganic anion transmembrane transporter activity	5/5114	10/18639	0.5	1.82235041063747	0.109797315403377	0.294662343499044
GO:0051880	G-quadruplex DNA binding	5/5114	10/18639	0.5	1.82235041063747	0.109797315403377	0.294662343499044
GO:0008376	acetylgalactosaminyltransferase activity	13/5114	34/18639	0.382352941176471	1.39356207872277	0.113206671374366	0.302031861518328
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	13/5114	34/18639	0.382352941176471	1.39356207872277	0.113206671374366	0.302031861518328
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	13/5114	34/18639	0.382352941176471	1.39356207872277	0.113206671374366	0.302031861518328
GO:0070851	growth factor receptor binding	45/5114	139/18639	0.323741007194245	1.17993911480124	0.113479895046499	0.30217063671251
GO:0005172	vascular endothelial growth factor receptor binding	6/5114	13/18639	0.461538461538462	1.6821696098192	0.117141658410996	0.307131488271442
GO:0031432	titin binding	6/5114	13/18639	0.461538461538462	1.6821696098192	0.117141658410996	0.307131488271442
GO:0031994	insulin-like growth factor I binding	6/5114	13/18639	0.461538461538462	1.6821696098192	0.117141658410996	0.307131488271442
GO:0035673	oligopeptide transmembrane transporter activity	6/5114	13/18639	0.461538461538462	1.6821696098192	0.117141658410996	0.307131488271442
GO:0046974	histone H3K9 methyltransferase activity	6/5114	13/18639	0.461538461538462	1.6821696098192	0.117141658410996	0.307131488271442
GO:0046975	histone H3K36 methyltransferase activity	6/5114	13/18639	0.461538461538462	1.6821696098192	0.117141658410996	0.307131488271442
GO:0052650	all-trans-retinol dehydrogenase (NADP+) activity	6/5114	13/18639	0.461538461538462	1.6821696098192	0.117141658410996	0.307131488271442
GO:0097157	pre-mRNA intronic binding	6/5114	13/18639	0.461538461538462	1.6821696098192	0.117141658410996	0.307131488271442
GO:0015296	monoatomic anion:monoatomic cation symporter activity	10/5114	25/18639	0.4	1.45788032850997	0.119967316160326	0.307667840791644
GO:0017025	TBP-class protein binding	10/5114	25/18639	0.4	1.45788032850997	0.119967316160326	0.307667840791644
GO:0017056	structural constituent of nuclear pore	10/5114	25/18639	0.4	1.45788032850997	0.119967316160326	0.307667840791644
GO:0140938	histone H3 methyltransferase activity	17/5114	47/18639	0.361702127659574	1.31829604173774	0.120484663779336	0.307667840791644
GO:0005159	insulin-like growth factor receptor binding	7/5114	16/18639	0.4375	1.59455660930778	0.120545952234626	0.307667840791644
GO:0015378	sodium:chloride symporter activity	7/5114	16/18639	0.4375	1.59455660930778	0.120545952234626	0.307667840791644
GO:0015385	sodium:proton antiporter activity	7/5114	16/18639	0.4375	1.59455660930778	0.120545952234626	0.307667840791644
GO:0015923	mannosidase activity	7/5114	16/18639	0.4375	1.59455660930778	0.120545952234626	0.307667840791644
GO:0055102	lipase inhibitor activity	7/5114	16/18639	0.4375	1.59455660930778	0.120545952234626	0.307667840791644
GO:0070411	I-SMAD binding	7/5114	16/18639	0.4375	1.59455660930778	0.120545952234626	0.307667840791644
GO:0015377	chloride:monoatomic cation symporter activity	9/5114	22/18639	0.409090909090909	1.49101397233974	0.121260550897292	0.307667840791644
GO:0061133	endopeptidase activator activity	9/5114	22/18639	0.409090909090909	1.49101397233974	0.121260550897292	0.307667840791644
GO:0140035	ubiquitin-like protein reader activity	9/5114	22/18639	0.409090909090909	1.49101397233974	0.121260550897292	0.307667840791644
GO:0140517	protein-RNA adaptor activity	9/5114	22/18639	0.409090909090909	1.49101397233974	0.121260550897292	0.307667840791644
GO:0005346	purine ribonucleotide transmembrane transporter activity	8/5114	19/18639	0.421052631578947	1.53461087211576	0.121625647165071	0.307667840791644
GO:0005520	insulin-like growth factor binding	8/5114	19/18639	0.421052631578947	1.53461087211576	0.121625647165071	0.307667840791644
GO:0030506	ankyrin binding	8/5114	19/18639	0.421052631578947	1.53461087211576	0.121625647165071	0.307667840791644
GO:0031420	alkali metal ion binding	8/5114	19/18639	0.421052631578947	1.53461087211576	0.121625647165071	0.307667840791644
GO:0046624	sphingolipid transporter activity	8/5114	19/18639	0.421052631578947	1.53461087211576	0.121625647165071	0.307667840791644
GO:0001540	amyloid-beta binding	28/5114	83/18639	0.337349397590361	1.22953762645419	0.122989034653276	0.310541629087569
GO:0001046	core promoter sequence-specific DNA binding	16/5114	44/18639	0.363636363636364	1.32534575319088	0.124450312659033	0.313651526000441
GO:0016504	peptidase activator activity	20/5114	57/18639	0.350877192982456	1.2788423934298	0.126627078743796	0.318549888699864
GO:0015175	neutral L-amino acid transmembrane transporter activity	15/5114	41/18639	0.365853658536585	1.33342712973473	0.128505799909456	0.322089766378564
GO:0140828	metal cation:monoatomic cation antiporter activity	15/5114	41/18639	0.365853658536585	1.33342712973473	0.128505799909456	0.322089766378564
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	23/5114	67/18639	0.343283582089552	1.25116595357199	0.130293616891122	0.325972675225775
GO:0005319	lipid transporter activity	56/5114	178/18639	0.314606741573034	1.14664744938987	0.130999183431256	0.327055434621758
GO:0050661	NADP binding	19/5114	54/18639	0.351851851851852	1.28239473341155	0.131205254884863	0.327055434621758
GO:0034061	DNA polymerase activity	13/5114	35/18639	0.371428571428571	1.35374601933069	0.136811486514845	0.340408908158977
GO:0030515	snoRNA binding	12/5114	32/18639	0.375	1.3667628079781	0.140998292702158	0.348919688099904
GO:0031369	translation initiation factor binding	12/5114	32/18639	0.375	1.3667628079781	0.140998292702158	0.348919688099904
GO:0042910	xenobiotic transmembrane transporter activity	12/5114	32/18639	0.375	1.3667628079781	0.140998292702158	0.348919688099904
GO:0004725	protein tyrosine phosphatase activity	32/5114	98/18639	0.326530612244898	1.19010639062039	0.147833081065839	0.365171769866069
GO:0004529	DNA exonuclease activity	10/5114	26/18639	0.384615384615385	1.40180800818267	0.149139993504346	0.367735074236347
GO:0160215	deacylase activity	22/5114	65/18639	0.338461538461538	1.23359104720075	0.153693921822114	0.375267786239644
GO:0015293	symporter activity	46/5114	146/18639	0.315068493150685	1.14833039574416	0.155462843731656	0.375267786239644
GO:0001614	purinergic nucleotide receptor activity	8/5114	20/18639	0.4	1.45788032850997	0.156103303864167	0.375267786239644
GO:0015095	magnesium ion transmembrane transporter activity	8/5114	20/18639	0.4	1.45788032850997	0.156103303864167	0.375267786239644
GO:0016502	nucleotide receptor activity	8/5114	20/18639	0.4	1.45788032850997	0.156103303864167	0.375267786239644
GO:0031418	L-ascorbic acid binding	8/5114	20/18639	0.4	1.45788032850997	0.156103303864167	0.375267786239644
GO:0000099	sulfur amino acid transmembrane transporter activity	5/5114	11/18639	0.454545454545455	1.6566821914886	0.157456699253634	0.375267786239644
GO:0001161	intronic transcription regulatory region sequence-specific DNA binding	5/5114	11/18639	0.454545454545455	1.6566821914886	0.157456699253634	0.375267786239644
GO:0002162	dystroglycan binding	5/5114	11/18639	0.454545454545455	1.6566821914886	0.157456699253634	0.375267786239644
GO:0004954	prostanoid receptor activity	5/5114	11/18639	0.454545454545455	1.6566821914886	0.157456699253634	0.375267786239644
GO:0008526	phosphatidylinositol transfer activity	5/5114	11/18639	0.454545454545455	1.6566821914886	0.157456699253634	0.375267786239644
GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	5/5114	11/18639	0.454545454545455	1.6566821914886	0.157456699253634	0.375267786239644
GO:0019107	myristoyltransferase activity	5/5114	11/18639	0.454545454545455	1.6566821914886	0.157456699253634	0.375267786239644
GO:0019864	IgG binding	5/5114	11/18639	0.454545454545455	1.6566821914886	0.157456699253634	0.375267786239644
GO:0032404	mismatch repair complex binding	5/5114	11/18639	0.454545454545455	1.6566821914886	0.157456699253634	0.375267786239644
GO:0034713	type I transforming growth factor beta receptor binding	5/5114	11/18639	0.454545454545455	1.6566821914886	0.157456699253634	0.375267786239644
GO:0008238	exopeptidase activity	33/5114	102/18639	0.323529411764706	1.17916791276542	0.157504137708712	0.375267786239644
GO:0005092	GDP-dissociation inhibitor activity	7/5114	17/18639	0.411764705882353	1.50075916170144	0.158475517181384	0.375267786239644
GO:0008429	phosphatidylethanolamine binding	7/5114	17/18639	0.411764705882353	1.50075916170144	0.158475517181384	0.375267786239644
GO:0140789	histone phosphatase activity	43/5114	136/18639	0.316176470588235	1.15236864202075	0.158530698635823	0.375267786239644
GO:0008174	mRNA methyltransferase activity	6/5114	14/18639	0.428571428571429	1.56201463768926	0.159337713044651	0.375267786239644
GO:0008474	palmitoyl-(protein) hydrolase activity	6/5114	14/18639	0.428571428571429	1.56201463768926	0.159337713044651	0.375267786239644
GO:0019992	diacylglycerol binding	6/5114	14/18639	0.428571428571429	1.56201463768926	0.159337713044651	0.375267786239644
GO:0098599	palmitoyl hydrolase activity	6/5114	14/18639	0.428571428571429	1.56201463768926	0.159337713044651	0.375267786239644
GO:0098847	sequence-specific single stranded DNA binding	6/5114	14/18639	0.428571428571429	1.56201463768926	0.159337713044651	0.375267786239644
GO:1901474	azole transmembrane transporter activity	6/5114	14/18639	0.428571428571429	1.56201463768926	0.159337713044651	0.375267786239644
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	56/5114	181/18639	0.30939226519337	1.12764224304639	0.163995684082891	0.385573329530516
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	29/5114	89/18639	0.325842696629214	1.18759914401093	0.165229922160732	0.387142493433207
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	29/5114	89/18639	0.325842696629214	1.18759914401093	0.165229922160732	0.387142493433207
GO:0001786	phosphatidylserine binding	20/5114	59/18639	0.338983050847458	1.23549180382201	0.166055095781237	0.388409693214332
GO:0016835	carbon-oxygen lyase activity	26/5114	79/18639	0.329113924050633	1.19952178928036	0.166494252706784	0.388746775669326
GO:0033218	amide binding	75/5114	247/18639	0.303643724696356	1.10669053277579	0.166768382534572	0.388746775669326
GO:0019239	deaminase activity	12/5114	33/18639	0.363636363636364	1.32534575319088	0.168903900172471	0.392385591216998
GO:0019956	chemokine binding	12/5114	33/18639	0.363636363636364	1.32534575319088	0.168903900172471	0.392385591216998
GO:0004180	carboxypeptidase activity	16/5114	46/18639	0.347826086956522	1.26772202479128	0.169679493027155	0.393518145119005
GO:0016769	transferase activity, transferring nitrogenous groups	11/5114	30/18639	0.366666666666667	1.33639030113414	0.175125606195121	0.405460301800907
GO:0004683	calcium/calmodulin-dependent protein kinase activity	10/5114	27/18639	0.37037037037037	1.34988919306479	0.181522282145901	0.418850401032603
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	10/5114	27/18639	0.37037037037037	1.34988919306479	0.181522282145901	0.418850401032603
GO:0140793	histone H2AXY142 phosphatase activity	29/5114	90/18639	0.322222222222222	1.17440359796637	0.182749446993476	0.420970901506051
GO:0004622	lysophospholipase activity	9/5114	24/18639	0.375	1.3667628079781	0.188044287422268	0.428828875824405
GO:0015295	solute:proton symporter activity	9/5114	24/18639	0.375	1.3667628079781	0.188044287422268	0.428828875824405
GO:0042625	ATPase-coupled ion transmembrane transporter activity	9/5114	24/18639	0.375	1.3667628079781	0.188044287422268	0.428828875824405
GO:0043998	histone H2A acetyltransferase activity	9/5114	24/18639	0.375	1.3667628079781	0.188044287422268	0.428828875824405
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	9/5114	24/18639	0.375	1.3667628079781	0.188044287422268	0.428828875824405
GO:0046961	proton-transporting ATPase activity, rotational mechanism	9/5114	24/18639	0.375	1.3667628079781	0.188044287422268	0.428828875824405
GO:0043394	proteoglycan binding	13/5114	37/18639	0.351351351351351	1.28057055882633	0.191266748675651	0.435450631151565
GO:0016757	glycosyltransferase activity	80/5114	267/18639	0.299625468164794	1.09204518989511	0.193499932536447	0.43980184333575
GO:0005123	death receptor binding	8/5114	21/18639	0.380952380952381	1.38845745572378	0.194599676467411	0.440834424634302
GO:0010314	phosphatidylinositol-5-phosphate binding	8/5114	21/18639	0.380952380952381	1.38845745572378	0.194599676467411	0.440834424634302
GO:0008175	tRNA methyltransferase activity	12/5114	34/18639	0.352941176470588	1.28636499574409	0.199284206789618	0.449954093346477
GO:0015035	protein-disulfide reductase activity	12/5114	34/18639	0.352941176470588	1.28636499574409	0.199284206789618	0.449954093346477
GO:0048029	monosaccharide binding	24/5114	74/18639	0.324324324324324	1.1820651312243	0.200340997216263	0.451593732999036
GO:0015373	monoatomic anion:sodium symporter activity	7/5114	18/18639	0.388888888888889	1.41738365271803	0.201018097288698	0.451629475158489
GO:0034185	apolipoprotein binding	7/5114	18/18639	0.388888888888889	1.41738365271803	0.201018097288698	0.451629475158489
GO:0140767	enzyme-substrate adaptor activity	43/5114	139/18639	0.309352517985612	1.12749737636563	0.201373207104399	0.451684402142216
GO:0017069	snRNA binding	18/5114	54/18639	0.333333333333333	1.21490027375831	0.204046142061192	0.454209871315181
GO:0003774	cytoskeletal motor activity	47/5114	153/18639	0.30718954248366	1.11961397777727	0.204141316474946	0.454209871315181
GO:0042626	ATPase-coupled transmembrane transporter activity	31/5114	98/18639	0.316326530612245	1.1529155659135	0.204590300691564	0.454209871315181
GO:0004559	alpha-mannosidase activity	6/5114	15/18639	0.4	1.45788032850997	0.206974384106626	0.454209871315181
GO:0004953	icosanoid receptor activity	6/5114	15/18639	0.4	1.45788032850997	0.206974384106626	0.454209871315181
GO:0005041	low-density lipoprotein particle receptor activity	6/5114	15/18639	0.4	1.45788032850997	0.206974384106626	0.454209871315181
GO:0033130	acetylcholine receptor binding	6/5114	15/18639	0.4	1.45788032850997	0.206974384106626	0.454209871315181
GO:0034483	heparan sulfate sulfotransferase activity	6/5114	15/18639	0.4	1.45788032850997	0.206974384106626	0.454209871315181
GO:0050700	CARD domain binding	6/5114	15/18639	0.4	1.45788032850997	0.206974384106626	0.454209871315181
GO:0050780	dopamine receptor binding	6/5114	15/18639	0.4	1.45788032850997	0.206974384106626	0.454209871315181
GO:0141050	histone H3K deacetylase activity	6/5114	15/18639	0.4	1.45788032850997	0.206974384106626	0.454209871315181
GO:0141051	histone H4K deacetylase activity	6/5114	15/18639	0.4	1.45788032850997	0.206974384106626	0.454209871315181
GO:0044325	transmembrane transporter binding	42/5114	136/18639	0.308823529411765	1.12556937127608	0.208317404411876	0.454209871315181
GO:0019842	vitamin binding	46/5114	150/18639	0.306666666666667	1.11770825185765	0.210961076362346	0.454209871315181
GO:0016836	hydro-lyase activity	20/5114	61/18639	0.327868852459016	1.19498387582785	0.211242496707325	0.454209871315181
GO:0004000	adenosine deaminase activity	5/5114	12/18639	0.416666666666667	1.51862534219789	0.211809434866596	0.454209871315181
GO:0004875	complement receptor activity	5/5114	12/18639	0.416666666666667	1.51862534219789	0.211809434866596	0.454209871315181
GO:0005527	macrolide binding	5/5114	12/18639	0.416666666666667	1.51862534219789	0.211809434866596	0.454209871315181
GO:0015368	calcium:monoatomic cation antiporter activity	5/5114	12/18639	0.416666666666667	1.51862534219789	0.211809434866596	0.454209871315181
GO:0016423	tRNA (guanine) methyltransferase activity	5/5114	12/18639	0.416666666666667	1.51862534219789	0.211809434866596	0.454209871315181
GO:0016840	carbon-nitrogen lyase activity	5/5114	12/18639	0.416666666666667	1.51862534219789	0.211809434866596	0.454209871315181
GO:0017166	vinculin binding	5/5114	12/18639	0.416666666666667	1.51862534219789	0.211809434866596	0.454209871315181
GO:0034452	dynactin binding	5/5114	12/18639	0.416666666666667	1.51862534219789	0.211809434866596	0.454209871315181
GO:0035251	UDP-glucosyltransferase activity	5/5114	12/18639	0.416666666666667	1.51862534219789	0.211809434866596	0.454209871315181
GO:0042301	phosphate ion binding	5/5114	12/18639	0.416666666666667	1.51862534219789	0.211809434866596	0.454209871315181
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	5/5114	12/18639	0.416666666666667	1.51862534219789	0.211809434866596	0.454209871315181
GO:0070410	co-SMAD binding	5/5114	12/18639	0.416666666666667	1.51862534219789	0.211809434866596	0.454209871315181
GO:0106019	phosphatidylinositol-4,5-bisphosphate phosphatase activity	5/5114	12/18639	0.416666666666667	1.51862534219789	0.211809434866596	0.454209871315181
GO:0046625	sphingolipid binding	10/5114	28/18639	0.357142857142857	1.30167886474105	0.216775341057098	0.464130275680243
GO:0016879	ligase activity, forming carbon-nitrogen bonds	16/5114	48/18639	0.333333333333333	1.21490027375831	0.22213737875316	0.474866446599087
GO:0019955	cytokine binding	44/5114	144/18639	0.305555555555556	1.11365858427845	0.225360359790209	0.481003517927227
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	9/5114	25/18639	0.36	1.31209229565898	0.22633758375711	0.481584329302512
GO:0047617	fatty acyl-CoA hydrolase activity	9/5114	25/18639	0.36	1.31209229565898	0.22633758375711	0.481584329302512
GO:0008374	O-acyltransferase activity	18/5114	55/18639	0.327272727272727	1.1928111778718	0.229765682068299	0.488118074191752
GO:0005518	collagen binding	23/5114	72/18639	0.319444444444444	1.16427942901838	0.230976015883419	0.489927387727872
GO:0008093	cytoskeletal anchor activity	8/5114	22/18639	0.363636363636364	1.32534575319088	0.236507748221765	0.490987209834241
GO:0031683	G-protein beta/gamma-subunit complex binding	8/5114	22/18639	0.363636363636364	1.32534575319088	0.236507748221765	0.490987209834241
GO:0032931	histone H3K56 acetyltransferase activity	8/5114	22/18639	0.363636363636364	1.32534575319088	0.236507748221765	0.490987209834241
GO:0043992	histone H3K9 acetyltransferase activity	8/5114	22/18639	0.363636363636364	1.32534575319088	0.236507748221765	0.490987209834241
GO:0043993	histone H3K18 acetyltransferase activity	8/5114	22/18639	0.363636363636364	1.32534575319088	0.236507748221765	0.490987209834241
GO:0043994	histone H3K23 acetyltransferase activity	8/5114	22/18639	0.363636363636364	1.32534575319088	0.236507748221765	0.490987209834241
GO:0043999	histone H2AK5 acetyltransferase activity	8/5114	22/18639	0.363636363636364	1.32534575319088	0.236507748221765	0.490987209834241
GO:0044012	histone H2AK9 acetyltransferase activity	8/5114	22/18639	0.363636363636364	1.32534575319088	0.236507748221765	0.490987209834241
GO:0044014	histone H2BK5 acetyltransferase activity	8/5114	22/18639	0.363636363636364	1.32534575319088	0.236507748221765	0.490987209834241
GO:0044015	histone H2BK12 acetyltransferase activity	8/5114	22/18639	0.363636363636364	1.32534575319088	0.236507748221765	0.490987209834241
GO:0044016	histone H3K4 acetyltransferase activity	8/5114	22/18639	0.363636363636364	1.32534575319088	0.236507748221765	0.490987209834241
GO:0044017	histone H3K27 acetyltransferase activity	8/5114	22/18639	0.363636363636364	1.32534575319088	0.236507748221765	0.490987209834241
GO:0044018	histone H3K36 acetyltransferase activity	8/5114	22/18639	0.363636363636364	1.32534575319088	0.236507748221765	0.490987209834241
GO:0140908	histone H3K122 acetyltransferase activity	8/5114	22/18639	0.363636363636364	1.32534575319088	0.236507748221765	0.490987209834241
GO:0097001	ceramide binding	7/5114	19/18639	0.368421052631579	1.34278451310129	0.247330359860813	0.512675677647755
GO:0043236	laminin binding	10/5114	29/18639	0.344827586206897	1.25679338664653	0.254479601604705	0.52669566029095
GO:0030170	pyridoxal phosphate binding	18/5114	56/18639	0.321428571428571	1.17151097826694	0.256783523616875	0.530660050318686
GO:0004707	MAP kinase activity	6/5114	16/18639	0.375	1.3667628079781	0.258831443229825	0.530876503681593
GO:0004708	MAP kinase kinase activity	6/5114	16/18639	0.375	1.3667628079781	0.258831443229825	0.530876503681593
GO:0005149	interleukin-1 receptor binding	6/5114	16/18639	0.375	1.3667628079781	0.258831443229825	0.530876503681593
GO:0005521	lamin binding	6/5114	16/18639	0.375	1.3667628079781	0.258831443229825	0.530876503681593
GO:0017070	U6 snRNA binding	6/5114	16/18639	0.375	1.3667628079781	0.258831443229825	0.530876503681593
GO:0016278	lysine N-methyltransferase activity	22/5114	70/18639	0.314285714285714	1.14547740097212	0.265076959913378	0.542871255234894
GO:0005160	transforming growth factor beta receptor binding	9/5114	26/18639	0.346153846153846	1.2616272073644	0.267206896243869	0.543161637305246
GO:0008143	poly(A) binding	9/5114	26/18639	0.346153846153846	1.2616272073644	0.267206896243869	0.543161637305246
GO:0016289	acyl-CoA hydrolase activity	9/5114	26/18639	0.346153846153846	1.2616272073644	0.267206896243869	0.543161637305246
GO:0043548	phosphatidylinositol 3-kinase binding	9/5114	26/18639	0.346153846153846	1.2616272073644	0.267206896243869	0.543161637305246
GO:0051139	metal cation:proton antiporter activity	9/5114	26/18639	0.346153846153846	1.2616272073644	0.267206896243869	0.543161637305246
GO:0005246	calcium channel regulator activity	17/5114	53/18639	0.320754716981132	1.16905498040894	0.268302941951421	0.544344562024615
GO:0017154	semaphorin receptor activity	5/5114	13/18639	0.384615384615385	1.40180800818267	0.270976795151346	0.544344562024615
GO:0019855	calcium channel inhibitor activity	5/5114	13/18639	0.384615384615385	1.40180800818267	0.270976795151346	0.544344562024615
GO:0030955	potassium ion binding	5/5114	13/18639	0.384615384615385	1.40180800818267	0.270976795151346	0.544344562024615
GO:0045028	G protein-coupled purinergic nucleotide receptor activity	5/5114	13/18639	0.384615384615385	1.40180800818267	0.270976795151346	0.544344562024615
GO:0061459	L-arginine transmembrane transporter activity	5/5114	13/18639	0.384615384615385	1.40180800818267	0.270976795151346	0.544344562024615
GO:0071714	icosanoid transmembrane transporter activity	5/5114	13/18639	0.384615384615385	1.40180800818267	0.270976795151346	0.544344562024615
GO:0140410	monoatomic cation:bicarbonate symporter activity	5/5114	13/18639	0.384615384615385	1.40180800818267	0.270976795151346	0.544344562024615
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	28/5114	91/18639	0.307692307692308	1.12144640654613	0.27179109303323	0.5451786095204
GO:0005178	integrin binding	48/5114	161/18639	0.298136645962733	1.08661887839253	0.274770498886404	0.550346776361917
GO:0005283	amino acid:sodium symporter activity	8/5114	23/18639	0.347826086956522	1.26772202479128	0.28111514670848	0.553316284250267
GO:0044013	histone H2B acetyltransferase activity	8/5114	23/18639	0.347826086956522	1.26772202479128	0.28111514670848	0.553316284250267
GO:0000182	rDNA binding	4/5114	10/18639	0.4	1.45788032850997	0.283544215940839	0.553316284250267
GO:0001094	TFIID-class transcription factor complex binding	4/5114	10/18639	0.4	1.45788032850997	0.283544215940839	0.553316284250267
GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	4/5114	10/18639	0.4	1.45788032850997	0.283544215940839	0.553316284250267
GO:0005131	growth hormone receptor binding	4/5114	10/18639	0.4	1.45788032850997	0.283544215940839	0.553316284250267
GO:0005337	nucleoside transmembrane transporter activity	4/5114	10/18639	0.4	1.45788032850997	0.283544215940839	0.553316284250267
GO:0005345	purine nucleobase transmembrane transporter activity	4/5114	10/18639	0.4	1.45788032850997	0.283544215940839	0.553316284250267
GO:0005522	profilin binding	4/5114	10/18639	0.4	1.45788032850997	0.283544215940839	0.553316284250267
GO:0008297	single-stranded DNA exodeoxyribonuclease activity	4/5114	10/18639	0.4	1.45788032850997	0.283544215940839	0.553316284250267
GO:0008641	ubiquitin-like modifier activating enzyme activity	4/5114	10/18639	0.4	1.45788032850997	0.283544215940839	0.553316284250267
GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor	4/5114	10/18639	0.4	1.45788032850997	0.283544215940839	0.553316284250267
GO:0045322	unmethylated CpG binding	4/5114	10/18639	0.4	1.45788032850997	0.283544215940839	0.553316284250267
GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding	4/5114	10/18639	0.4	1.45788032850997	0.283544215940839	0.553316284250267
GO:0050815	phosphoserine residue binding	4/5114	10/18639	0.4	1.45788032850997	0.283544215940839	0.553316284250267
GO:0070097	delta-catenin binding	4/5114	10/18639	0.4	1.45788032850997	0.283544215940839	0.553316284250267
GO:0070513	death domain binding	4/5114	10/18639	0.4	1.45788032850997	0.283544215940839	0.553316284250267
GO:0098505	G-rich strand telomeric DNA binding	4/5114	10/18639	0.4	1.45788032850997	0.283544215940839	0.553316284250267
GO:0015294	solute:monoatomic cation symporter activity	35/5114	116/18639	0.301724137931034	1.09969421331571	0.284884395289508	0.554455304059668
GO:0070279	vitamin B6 binding	18/5114	57/18639	0.315789473684211	1.15095815408682	0.284939695058483	0.554455304059668
GO:0004177	aminopeptidase activity	13/5114	40/18639	0.325	1.18452776691435	0.287998836487309	0.558023277505907
GO:0015144	carbohydrate transmembrane transporter activity	13/5114	40/18639	0.325	1.18452776691435	0.287998836487309	0.558023277505907
GO:0050997	quaternary ammonium group binding	13/5114	40/18639	0.325	1.18452776691435	0.287998836487309	0.558023277505907
GO:0140359	ABC-type transporter activity	15/5114	47/18639	0.319148936170213	1.1632023897686	0.293762229410006	0.568384143589332
GO:0016505	peptidase activator activity involved in apoptotic process	7/5114	20/18639	0.35	1.27564528744623	0.296452620782084	0.572778330959445
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	17/5114	54/18639	0.314814814814815	1.14740581410507	0.297826336495581	0.57461973962283
GO:0008194	UDP-glycosyltransferase activity	43/5114	145/18639	0.296551724137931	1.08084231251601	0.302372648590688	0.581856845289161
GO:0019213	deacetylase activity	12/5114	37/18639	0.324324324324324	1.1820651312243	0.302429253407983	0.581856845289161
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	6/5114	17/18639	0.352941176470588	1.28636499574409	0.313571039256247	0.599074181292355
GO:0016805	dipeptidase activity	6/5114	17/18639	0.352941176470588	1.28636499574409	0.313571039256247	0.599074181292355
GO:0017110	nucleoside diphosphate phosphatase activity	6/5114	17/18639	0.352941176470588	1.28636499574409	0.313571039256247	0.599074181292355
GO:0038191	neuropilin binding	6/5114	17/18639	0.352941176470588	1.28636499574409	0.313571039256247	0.599074181292355
GO:0045236	CXCR chemokine receptor binding	6/5114	17/18639	0.352941176470588	1.28636499574409	0.313571039256247	0.599074181292355
GO:0090482	vitamin transmembrane transporter activity	11/5114	34/18639	0.323529411764706	1.17916791276542	0.318120181608743	0.60691643586249
GO:0140033	acetylation-dependent protein binding	8/5114	24/18639	0.333333333333333	1.21490027375831	0.327650576351586	0.624226899994792
GO:0016279	protein-lysine N-methyltransferase activity	21/5114	69/18639	0.304347826086957	1.10925677169237	0.329917831556843	0.627670972014829
GO:0004065	arylsulfatase activity	5/5114	14/18639	0.357142857142857	1.30167886474105	0.332998507432843	0.6291507069893
GO:0004705	JUN kinase activity	5/5114	14/18639	0.357142857142857	1.30167886474105	0.332998507432843	0.6291507069893
GO:0008191	metalloendopeptidase inhibitor activity	5/5114	14/18639	0.357142857142857	1.30167886474105	0.332998507432843	0.6291507069893
GO:0008494	translation activator activity	5/5114	14/18639	0.357142857142857	1.30167886474105	0.332998507432843	0.6291507069893
GO:1990825	sequence-specific mRNA binding	5/5114	14/18639	0.357142857142857	1.30167886474105	0.332998507432843	0.6291507069893
GO:0008327	methyl-CpG binding	10/5114	31/18639	0.32258064516129	1.17570994234675	0.335291676346201	0.631735765364014
GO:0070273	phosphatidylinositol-4-phosphate binding	10/5114	31/18639	0.32258064516129	1.17570994234675	0.335291676346201	0.631735765364014
GO:0042887	amide transmembrane transporter activity	12/5114	38/18639	0.315789473684211	1.15095815408682	0.339663309643949	0.639091020624841
GO:0051539	4 iron, 4 sulfur cluster binding	14/5114	45/18639	0.311111111111111	1.13390692217442	0.342146318999891	0.642877402687552
GO:0000049	tRNA binding	24/5114	80/18639	0.3	1.09341024638248	0.342781262845003	0.643185721217409
GO:0036002	pre-mRNA binding	18/5114	59/18639	0.305084745762712	1.11194262343981	0.343954331764753	0.644501532497466
GO:0051119	sugar transmembrane transporter activity	9/5114	28/18639	0.321428571428571	1.17151097826694	0.354231559088737	0.649387315509015
GO:0000014	single-stranded DNA endodeoxyribonuclease activity	4/5114	11/18639	0.363636363636364	1.32534575319088	0.355594225476386	0.649387315509015
GO:0004117	calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity	4/5114	11/18639	0.363636363636364	1.32534575319088	0.355594225476386	0.649387315509015
GO:0004143	ATP-dependent diacylglycerol kinase activity	4/5114	11/18639	0.363636363636364	1.32534575319088	0.355594225476386	0.649387315509015
GO:0008199	ferric iron binding	4/5114	11/18639	0.363636363636364	1.32534575319088	0.355594225476386	0.649387315509015
GO:0010854	adenylate cyclase regulator activity	4/5114	11/18639	0.363636363636364	1.32534575319088	0.355594225476386	0.649387315509015
GO:0015205	nucleobase transmembrane transporter activity	4/5114	11/18639	0.363636363636364	1.32534575319088	0.355594225476386	0.649387315509015
GO:0016176	superoxide-generating NADPH oxidase activator activity	4/5114	11/18639	0.363636363636364	1.32534575319088	0.355594225476386	0.649387315509015
GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor	4/5114	11/18639	0.363636363636364	1.32534575319088	0.355594225476386	0.649387315509015
GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	4/5114	11/18639	0.363636363636364	1.32534575319088	0.355594225476386	0.649387315509015
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	4/5114	11/18639	0.363636363636364	1.32534575319088	0.355594225476386	0.649387315509015
GO:0019206	nucleoside kinase activity	4/5114	11/18639	0.363636363636364	1.32534575319088	0.355594225476386	0.649387315509015
GO:0032794	GTPase activating protein binding	4/5114	11/18639	0.363636363636364	1.32534575319088	0.355594225476386	0.649387315509015
GO:0034056	estrogen response element binding	4/5114	11/18639	0.363636363636364	1.32534575319088	0.355594225476386	0.649387315509015
GO:0034594	phosphatidylinositol trisphosphate phosphatase activity	4/5114	11/18639	0.363636363636364	1.32534575319088	0.355594225476386	0.649387315509015
GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	4/5114	11/18639	0.363636363636364	1.32534575319088	0.355594225476386	0.649387315509015
GO:0047676	arachidonate-CoA ligase activity	4/5114	11/18639	0.363636363636364	1.32534575319088	0.355594225476386	0.649387315509015
GO:0048101	calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity	4/5114	11/18639	0.363636363636364	1.32534575319088	0.355594225476386	0.649387315509015
GO:0140937	histone H4K12 deacetylase activity, hydrolytic mechanism	4/5114	11/18639	0.363636363636364	1.32534575319088	0.355594225476386	0.649387315509015
GO:0035254	glutamate receptor binding	15/5114	49/18639	0.306122448979592	1.11572474120661	0.359675209005729	0.655963064755441
GO:0015171	amino acid transmembrane transporter activity	30/5114	102/18639	0.294117647058824	1.07197082978674	0.362651039307493	0.660508426258714
GO:0000400	four-way junction DNA binding	6/5114	18/18639	0.333333333333333	1.21490027375831	0.369847510240022	0.671824067803019
GO:0035615	clathrin adaptor activity	6/5114	18/18639	0.333333333333333	1.21490027375831	0.369847510240022	0.671824067803019
GO:0042054	histone methyltransferase activity	20/5114	67/18639	0.298507462686567	1.08797039441043	0.372701608603511	0.675870372812406
GO:0008013	beta-catenin binding	31/5114	106/18639	0.292452830188679	1.06590307037286	0.373064612811533	0.675870372812406
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	18/5114	60/18639	0.3	1.09341024638248	0.374431942973266	0.677449051790042
GO:0008378	galactosyltransferase activity	10/5114	32/18639	0.3125	1.13896900664842	0.377356014483788	0.680559849564025
GO:0043425	bHLH transcription factor binding	10/5114	32/18639	0.3125	1.13896900664842	0.377356014483788	0.680559849564025
GO:0000217	DNA secondary structure binding	12/5114	39/18639	0.307692307692308	1.12144640654613	0.377693236260627	0.680559849564025
GO:0043178	alcohol binding	27/5114	92/18639	0.293478260869565	1.06964045841764	0.378144162385868	0.680559849564025
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	48/5114	167/18639	0.287425149700599	1.04757867916884	0.380443013276284	0.6837962580729
GO:0004536	DNA nuclease activity	19/5114	64/18639	0.296875	1.082020556316	0.38854052166579	0.69743278921875
GO:0004467	long-chain fatty acid-CoA ligase activity	5/5114	15/18639	0.333333333333333	1.21490027375831	0.396010569095952	0.703481081265353
GO:0005402	carbohydrate:monoatomic cation symporter activity	5/5114	15/18639	0.333333333333333	1.21490027375831	0.396010569095952	0.703481081265353
GO:0010181	FMN binding	5/5114	15/18639	0.333333333333333	1.21490027375831	0.396010569095952	0.703481081265353
GO:0015929	hexosaminidase activity	5/5114	15/18639	0.333333333333333	1.21490027375831	0.396010569095952	0.703481081265353
GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	5/5114	15/18639	0.333333333333333	1.21490027375831	0.396010569095952	0.703481081265353
GO:0048531	beta-1,3-galactosyltransferase activity	5/5114	15/18639	0.333333333333333	1.21490027375831	0.396010569095952	0.703481081265353
GO:0140776	protein-containing complex destabilizing activity	5/5114	15/18639	0.333333333333333	1.21490027375831	0.396010569095952	0.703481081265353
GO:0016409	palmitoyltransferase activity	11/5114	36/18639	0.305555555555556	1.11365858427845	0.397806777845848	0.703481081265353
GO:0008649	rRNA methyltransferase activity	7/5114	22/18639	0.318181818181818	1.15967753404202	0.399119053807661	0.703481081265353
GO:0016881	acid-amino acid ligase activity	7/5114	22/18639	0.318181818181818	1.15967753404202	0.399119053807661	0.703481081265353
GO:0046972	histone H4K16 acetyltransferase activity	7/5114	22/18639	0.318181818181818	1.15967753404202	0.399119053807661	0.703481081265353
GO:0005416	amino acid:monoatomic cation symporter activity	9/5114	29/18639	0.310344827586207	1.13111404798188	0.399119939956551	0.703481081265353
GO:0016417	S-acyltransferase activity	9/5114	29/18639	0.310344827586207	1.13111404798188	0.399119939956551	0.703481081265353
GO:0035250	UDP-galactosyltransferase activity	9/5114	29/18639	0.310344827586207	1.13111404798188	0.399119939956551	0.703481081265353
GO:0008514	organic anion transmembrane transporter activity	76/5114	269/18639	0.282527881040892	1.02972960006281	0.404143245550271	0.711417104924833
GO:0015026	coreceptor activity	18/5114	61/18639	0.295081967213115	1.07548548824506	0.405294216727534	0.712524967889075
GO:0030165	PDZ domain binding	24/5114	83/18639	0.289156626506024	1.05388939410359	0.42192462106222	0.726301895506504
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	8/5114	26/18639	0.307692307692308	1.12144640654613	0.423380782084594	0.726301895506504
GO:0008198	ferrous iron binding	8/5114	26/18639	0.307692307692308	1.12144640654613	0.423380782084594	0.726301895506504
GO:0015145	monosaccharide transmembrane transporter activity	8/5114	26/18639	0.307692307692308	1.12144640654613	0.423380782084594	0.726301895506504
GO:0034237	protein kinase A regulatory subunit binding	8/5114	26/18639	0.307692307692308	1.12144640654613	0.423380782084594	0.726301895506504
GO:0097602	cullin family protein binding	8/5114	26/18639	0.307692307692308	1.12144640654613	0.423380782084594	0.726301895506504
GO:0003756	protein disulfide isomerase activity	6/5114	19/18639	0.315789473684211	1.15095815408682	0.426393887338118	0.726301895506504
GO:0015355	secondary active monocarboxylate transmembrane transporter activity	6/5114	19/18639	0.315789473684211	1.15095815408682	0.426393887338118	0.726301895506504
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	6/5114	19/18639	0.315789473684211	1.15095815408682	0.426393887338118	0.726301895506504
GO:0022821	solute:potassium antiporter activity	6/5114	19/18639	0.315789473684211	1.15095815408682	0.426393887338118	0.726301895506504
GO:0042800	histone H3K4 methyltransferase activity	6/5114	19/18639	0.315789473684211	1.15095815408682	0.426393887338118	0.726301895506504
GO:0042834	peptidoglycan binding	6/5114	19/18639	0.315789473684211	1.15095815408682	0.426393887338118	0.726301895506504
GO:0046527	glucosyltransferase activity	6/5114	19/18639	0.315789473684211	1.15095815408682	0.426393887338118	0.726301895506504
GO:0050145	nucleoside monophosphate kinase activity	6/5114	19/18639	0.315789473684211	1.15095815408682	0.426393887338118	0.726301895506504
GO:0005025	transforming growth factor beta receptor activity, type I	4/5114	12/18639	0.333333333333333	1.21490027375831	0.42748662078128	0.726301895506504
GO:0005026	transforming growth factor beta receptor activity, type II	4/5114	12/18639	0.333333333333333	1.21490027375831	0.42748662078128	0.726301895506504
GO:0008499	N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity	4/5114	12/18639	0.333333333333333	1.21490027375831	0.42748662078128	0.726301895506504
GO:0008504	monoamine transmembrane transporter activity	4/5114	12/18639	0.333333333333333	1.21490027375831	0.42748662078128	0.726301895506504
GO:0015132	prostaglandin transmembrane transporter activity	4/5114	12/18639	0.333333333333333	1.21490027375831	0.42748662078128	0.726301895506504
GO:0015269	calcium-activated potassium channel activity	4/5114	12/18639	0.333333333333333	1.21490027375831	0.42748662078128	0.726301895506504
GO:0016361	activin receptor activity, type I	4/5114	12/18639	0.333333333333333	1.21490027375831	0.42748662078128	0.726301895506504
GO:0016362	activin receptor activity, type II	4/5114	12/18639	0.333333333333333	1.21490027375831	0.42748662078128	0.726301895506504
GO:0017002	activin receptor activity	4/5114	12/18639	0.333333333333333	1.21490027375831	0.42748662078128	0.726301895506504
GO:0035497	cAMP response element binding	4/5114	12/18639	0.333333333333333	1.21490027375831	0.42748662078128	0.726301895506504
GO:0043047	single-stranded telomeric DNA binding	4/5114	12/18639	0.333333333333333	1.21490027375831	0.42748662078128	0.726301895506504
GO:0141221	histone deacetylase activity, hydrolytic mechanism	4/5114	12/18639	0.333333333333333	1.21490027375831	0.42748662078128	0.726301895506504
GO:1990459	transferrin receptor binding	4/5114	12/18639	0.333333333333333	1.21490027375831	0.42748662078128	0.726301895506504
GO:0016790	thiolester hydrolase activity	13/5114	44/18639	0.295454545454545	1.07684342446759	0.43273609499016	0.733396409127244
GO:0019205	nucleobase-containing compound kinase activity	13/5114	44/18639	0.295454545454545	1.07684342446759	0.43273609499016	0.733396409127244
GO:0042805	actinin binding	11/5114	37/18639	0.297297297297297	1.08355970362228	0.438158807415715	0.741666581077902
GO:0070577	lysine-acetylated histone binding	7/5114	23/18639	0.304347826086957	1.10925677169237	0.450745763163554	0.761086171176038
GO:0140102	catalytic activity, acting on a rRNA	7/5114	23/18639	0.304347826086957	1.10925677169237	0.450745763163554	0.761086171176038
GO:0001530	lipopolysaccharide binding	12/5114	41/18639	0.292682926829268	1.06674170378778	0.454610426296867	0.765435456868352
GO:0016877	ligase activity, forming carbon-sulfur bonds	12/5114	41/18639	0.292682926829268	1.06674170378778	0.454610426296867	0.765435456868352
GO:0016829	lyase activity	56/5114	200/18639	0.28	1.02051622995698	0.455689249138416	0.765435456868352
GO:0000062	fatty-acyl-CoA binding	5/5114	16/18639	0.3125	1.13896900664842	0.45836471721692	0.765435456868352
GO:0015562	efflux transmembrane transporter activity	5/5114	16/18639	0.3125	1.13896900664842	0.45836471721692	0.765435456868352
GO:0016722	oxidoreductase activity, acting on metal ions	5/5114	16/18639	0.3125	1.13896900664842	0.45836471721692	0.765435456868352
GO:0031435	mitogen-activated protein kinase kinase kinase binding	5/5114	16/18639	0.3125	1.13896900664842	0.45836471721692	0.765435456868352
GO:0043023	ribosomal large subunit binding	5/5114	16/18639	0.3125	1.13896900664842	0.45836471721692	0.765435456868352
GO:0097027	ubiquitin-protein transferase activator activity	5/5114	16/18639	0.3125	1.13896900664842	0.45836471721692	0.765435456868352
GO:0052689	carboxylic ester hydrolase activity	26/5114	92/18639	0.282608695652174	1.03002414514292	0.468987164292524	0.78218191410995
GO:0141110	transporter inhibitor activity	13/5114	45/18639	0.288888888888889	1.05291357059054	0.469538191486207	0.78218191410995
GO:0031491	nucleosome binding	21/5114	74/18639	0.283783783783784	1.03430698982126	0.471776290550312	0.78495299986812
GO:0019212	phosphatase inhibitor activity	16/5114	56/18639	0.285714285714286	1.04134309179284	0.474848226419774	0.789103013734077
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	6/5114	20/18639	0.3	1.09341024638248	0.482083001576418	0.799242732121028
GO:0015085	calcium ion transmembrane transporter activity	41/5114	147/18639	0.27891156462585	1.01654920865491	0.482120066813856	0.799242732121028
GO:0016853	isomerase activity	50/5114	180/18639	0.277777777777778	1.01241689479859	0.487471027579022	0.807077157523833
GO:0005452	solute:inorganic anion antiporter activity	9/5114	31/18639	0.290322580645161	1.05813894811208	0.488618454811281	0.807077157523833
GO:0070325	lipoprotein particle receptor binding	9/5114	31/18639	0.290322580645161	1.05813894811208	0.488618454811281	0.807077157523833
GO:0022804	active transmembrane transporter activity	126/5114	457/18639	0.275711159737418	1.00488469032963	0.49220644511916	0.812021744000933
GO:0016251	RNA polymerase II general transcription initiation factor activity	15/5114	53/18639	0.283018867924528	1.03151910036083	0.495818930371665	0.816064396785125
GO:0015651	quaternary ammonium group transmembrane transporter activity	4/5114	13/18639	0.307692307692308	1.12144640654613	0.497046543283473	0.816064396785125
GO:0070123	transforming growth factor beta receptor activity, type III	4/5114	13/18639	0.307692307692308	1.12144640654613	0.497046543283473	0.816064396785125
GO:1901338	catecholamine binding	4/5114	13/18639	0.307692307692308	1.12144640654613	0.497046543283473	0.816064396785125
GO:0046943	carboxylic acid transmembrane transporter activity	52/5114	188/18639	0.276595744680851	1.00810873779945	0.50051022659429	0.816395869626311
GO:0005315	phosphate transmembrane transporter activity	7/5114	24/18639	0.291666666666667	1.06303773953852	0.501432016556717	0.816395869626311
GO:0015149	hexose transmembrane transporter activity	7/5114	24/18639	0.291666666666667	1.06303773953852	0.501432016556717	0.816395869626311
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	7/5114	24/18639	0.291666666666667	1.06303773953852	0.501432016556717	0.816395869626311
GO:0019957	C-C chemokine binding	7/5114	24/18639	0.291666666666667	1.06303773953852	0.501432016556717	0.816395869626311
GO:0055056	D-glucose transmembrane transporter activity	7/5114	24/18639	0.291666666666667	1.06303773953852	0.501432016556717	0.816395869626311
GO:0140612	DNA damage sensor activity	7/5114	24/18639	0.291666666666667	1.06303773953852	0.501432016556717	0.816395869626311
GO:0005343	organic acid:sodium symporter activity	10/5114	35/18639	0.285714285714286	1.04134309179284	0.504027329038235	0.819644442221701
GO:0005496	steroid binding	30/5114	108/18639	0.277777777777778	1.01241689479859	0.504940009158508	0.820152262200382
GO:0016776	phosphotransferase activity, phosphate group as acceptor	11/5114	39/18639	0.282051282051282	1.02799253933396	0.517805425374905	0.835540022119804
GO:0005342	organic acid transmembrane transporter activity	52/5114	189/18639	0.275132275132275	1.00277482913384	0.51844302770869	0.835540022119804
GO:0015278	intracellularly gated calcium channel activity	5/5114	17/18639	0.294117647058824	1.07197082978674	0.518695416367199	0.835540022119804
GO:0032977	membrane insertase activity	5/5114	17/18639	0.294117647058824	1.07197082978674	0.518695416367199	0.835540022119804
GO:0036041	long-chain fatty acid binding	5/5114	17/18639	0.294117647058824	1.07197082978674	0.518695416367199	0.835540022119804
GO:0070402	NADPH binding	5/5114	17/18639	0.294117647058824	1.07197082978674	0.518695416367199	0.835540022119804
GO:1901567	fatty acid derivative binding	5/5114	17/18639	0.294117647058824	1.07197082978674	0.518695416367199	0.835540022119804
GO:0004519	endonuclease activity	35/5114	127/18639	0.275590551181102	1.00444510822537	0.521534976854966	0.839124591736023
GO:0008170	N-methyltransferase activity	27/5114	98/18639	0.275510204081633	1.00415226708595	0.528377183870055	0.849133215489994
GO:0051287	NAD binding	15/5114	54/18639	0.277777777777778	1.01241689479859	0.529277502267413	0.849580573557328
GO:0015174	basic amino acid transmembrane transporter activity	6/5114	21/18639	0.285714285714286	1.04134309179284	0.535964565031217	0.853606387066451
GO:0140312	cargo adaptor activity	6/5114	21/18639	0.285714285714286	1.04134309179284	0.535964565031217	0.853606387066451
GO:0072341	modified amino acid binding	25/5114	91/18639	0.274725274725275	1.00129143441619	0.536885220264065	0.853606387066451
GO:0003680	minor groove of adenine-thymine-rich DNA binding	3/5114	10/18639	0.3	1.09341024638248	0.546158112954669	0.853606387066451
GO:0004935	adrenergic receptor activity	3/5114	10/18639	0.3	1.09341024638248	0.546158112954669	0.853606387066451
GO:0005528	FK506 binding	3/5114	10/18639	0.3	1.09341024638248	0.546158112954669	0.853606387066451
GO:0008239	dipeptidyl-peptidase activity	3/5114	10/18639	0.3	1.09341024638248	0.546158112954669	0.853606387066451
GO:0015187	glycine transmembrane transporter activity	3/5114	10/18639	0.3	1.09341024638248	0.546158112954669	0.853606387066451
GO:0015203	polyamine transmembrane transporter activity	3/5114	10/18639	0.3	1.09341024638248	0.546158112954669	0.853606387066451
GO:0015643	toxic substance binding	3/5114	10/18639	0.3	1.09341024638248	0.546158112954669	0.853606387066451
GO:0015924	mannosyl-oligosaccharide mannosidase activity	3/5114	10/18639	0.3	1.09341024638248	0.546158112954669	0.853606387066451
GO:0031078	histone H3K14 deacetylase activity, hydrolytic mechanism	3/5114	10/18639	0.3	1.09341024638248	0.546158112954669	0.853606387066451
GO:0032052	bile acid binding	3/5114	10/18639	0.3	1.09341024638248	0.546158112954669	0.853606387066451
GO:0032356	oxidized DNA binding	3/5114	10/18639	0.3	1.09341024638248	0.546158112954669	0.853606387066451
GO:0034739	histone H4K16 deacetylase activity, hydrolytic mechanism	3/5114	10/18639	0.3	1.09341024638248	0.546158112954669	0.853606387066451
GO:0035374	chondroitin sulfate binding	3/5114	10/18639	0.3	1.09341024638248	0.546158112954669	0.853606387066451
GO:0043121	neurotrophin binding	3/5114	10/18639	0.3	1.09341024638248	0.546158112954669	0.853606387066451
GO:0043208	glycosphingolipid binding	3/5114	10/18639	0.3	1.09341024638248	0.546158112954669	0.853606387066451
GO:0140999	histone H3K4 trimethyltransferase activity	3/5114	10/18639	0.3	1.09341024638248	0.546158112954669	0.853606387066451
GO:0180032	histone H4K5 deacetylase activity, hydrolytic mechanism	3/5114	10/18639	0.3	1.09341024638248	0.546158112954669	0.853606387066451
GO:0180033	histone H4K8 deacetylase activity, hydrolytic mechanism	3/5114	10/18639	0.3	1.09341024638248	0.546158112954669	0.853606387066451
GO:1990162	histone H3K4 deacetylase activity, hydrolytic mechanism	3/5114	10/18639	0.3	1.09341024638248	0.546158112954669	0.853606387066451
GO:1990757	ubiquitin ligase activator activity	3/5114	10/18639	0.3	1.09341024638248	0.546158112954669	0.853606387066451
GO:0003707	nuclear steroid receptor activity	7/5114	25/18639	0.28	1.02051622995698	0.550472747926389	0.854483833713009
GO:0015662	P-type ion transporter activity	7/5114	25/18639	0.28	1.02051622995698	0.550472747926389	0.854483833713009
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	7/5114	25/18639	0.28	1.02051622995698	0.550472747926389	0.854483833713009
GO:0019706	protein-cysteine S-palmitoyltransferase activity	7/5114	25/18639	0.28	1.02051622995698	0.550472747926389	0.854483833713009
GO:0019707	protein-cysteine S-acyltransferase activity	7/5114	25/18639	0.28	1.02051622995698	0.550472747926389	0.854483833713009
GO:0140358	P-type transmembrane transporter activity	7/5114	25/18639	0.28	1.02051622995698	0.550472747926389	0.854483833713009
GO:0016830	carbon-carbon lyase activity	14/5114	51/18639	0.274509803921569	1.00050610780096	0.552252322817773	0.856273181576706
GO:0008235	metalloexopeptidase activity	18/5114	66/18639	0.272727272727273	0.994009314893163	0.558687369580247	0.864226150215008
GO:0005347	ATP transmembrane transporter activity	4/5114	14/18639	0.285714285714286	1.04134309179284	0.562665757623725	0.864226150215008
GO:0015386	potassium:proton antiporter activity	4/5114	14/18639	0.285714285714286	1.04134309179284	0.562665757623725	0.864226150215008
GO:0070742	C2H2 zinc finger domain binding	4/5114	14/18639	0.285714285714286	1.04134309179284	0.562665757623725	0.864226150215008
GO:0071933	Arp2/3 complex binding	4/5114	14/18639	0.285714285714286	1.04134309179284	0.562665757623725	0.864226150215008
GO:0098821	BMP receptor activity	4/5114	14/18639	0.285714285714286	1.04134309179284	0.562665757623725	0.864226150215008
GO:0004629	phospholipase C activity	8/5114	29/18639	0.275862068965517	1.00543470931722	0.563075602995137	0.864226150215008
GO:0099604	ligand-gated calcium channel activity	8/5114	29/18639	0.275862068965517	1.00543470931722	0.563075602995137	0.864226150215008
GO:0106222	lncRNA binding	8/5114	29/18639	0.275862068965517	1.00543470931722	0.563075602995137	0.864226150215008
GO:0016248	channel inhibitor activity	12/5114	44/18639	0.272727272727273	0.994009314893163	0.566866824967422	0.869068555449492
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	33/5114	122/18639	0.270491803278689	0.985861697557973	0.572744279823916	0.871251759323395
GO:0030296	protein tyrosine kinase activator activity	9/5114	33/18639	0.272727272727273	0.994009314893163	0.574279362408432	0.871251759323395
GO:0000900	mRNA regulatory element binding translation repressor activity	5/5114	18/18639	0.277777777777778	1.01241689479859	0.575944611031498	0.871251759323395
GO:0003746	translation elongation factor activity	5/5114	18/18639	0.277777777777778	1.01241689479859	0.575944611031498	0.871251759323395
GO:0015172	acidic amino acid transmembrane transporter activity	5/5114	18/18639	0.277777777777778	1.01241689479859	0.575944611031498	0.871251759323395
GO:0016854	racemase and epimerase activity	5/5114	18/18639	0.277777777777778	1.01241689479859	0.575944611031498	0.871251759323395
GO:0017128	phospholipid scramblase activity	5/5114	18/18639	0.277777777777778	1.01241689479859	0.575944611031498	0.871251759323395
GO:0031690	adrenergic receptor binding	5/5114	18/18639	0.277777777777778	1.01241689479859	0.575944611031498	0.871251759323395
GO:0050811	GABA receptor binding	5/5114	18/18639	0.277777777777778	1.01241689479859	0.575944611031498	0.871251759323395
GO:0070064	proline-rich region binding	5/5114	18/18639	0.277777777777778	1.01241689479859	0.575944611031498	0.871251759323395
GO:0098641	cadherin binding involved in cell-cell adhesion	5/5114	18/18639	0.277777777777778	1.01241689479859	0.575944611031498	0.871251759323395
GO:0099602	neurotransmitter receptor regulator activity	5/5114	18/18639	0.277777777777778	1.01241689479859	0.575944611031498	0.871251759323395
GO:0043177	organic acid binding	51/5114	189/18639	0.26984126984127	0.983490697804347	0.583386966699723	0.881533845698918
GO:0016298	lipase activity	35/5114	130/18639	0.269230769230769	0.981265605727866	0.585635228358355	0.883807555646764
GO:0034062	5'-3' RNA polymerase activity	6/5114	22/18639	0.272727272727273	0.994009314893163	0.58728163174005	0.883807555646764
GO:0097747	RNA polymerase activity	6/5114	22/18639	0.272727272727273	0.994009314893163	0.58728163174005	0.883807555646764
GO:0008168	methyltransferase activity	55/5114	204/18639	0.269607843137255	0.982639927304516	0.587479692918933	0.883807555646764
GO:0017080	sodium channel regulator activity	11/5114	41/18639	0.268292682926829	0.977846561805469	0.593682616028721	0.888787012788715
GO:0016758	hexosyltransferase activity	53/5114	197/18639	0.269035532994924	0.980554028058738	0.593958453497626	0.888787012788715
GO:0005200	structural constituent of cytoskeleton	30/5114	112/18639	0.267857142857143	0.976259148555785	0.597211936798835	0.888787012788715
GO:0001637	G protein-coupled chemoattractant receptor activity	7/5114	26/18639	0.269230769230769	0.981265605727866	0.597296103762841	0.888787012788715
GO:0004435	phosphatidylinositol phospholipase C activity	7/5114	26/18639	0.269230769230769	0.981265605727866	0.597296103762841	0.888787012788715
GO:0004950	chemokine receptor activity	7/5114	26/18639	0.269230769230769	0.981265605727866	0.597296103762841	0.888787012788715
GO:0005227	calcium-activated cation channel activity	7/5114	26/18639	0.269230769230769	0.981265605727866	0.597296103762841	0.888787012788715
GO:0030507	spectrin binding	7/5114	26/18639	0.269230769230769	0.981265605727866	0.597296103762841	0.888787012788715
GO:0070006	metalloaminopeptidase activity	7/5114	26/18639	0.269230769230769	0.981265605727866	0.597296103762841	0.888787012788715
GO:0120014	phospholipid transfer activity	7/5114	26/18639	0.269230769230769	0.981265605727866	0.597296103762841	0.888787012788715
GO:0008009	chemokine activity	12/5114	45/18639	0.266666666666667	0.971920219006648	0.602259055324228	0.895196811287154
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	8/5114	30/18639	0.266666666666667	0.971920219006648	0.606337920882353	0.895806650409373
GO:0008106	alcohol dehydrogenase (NADP+) activity	8/5114	30/18639	0.266666666666667	0.971920219006648	0.606337920882353	0.895806650409373
GO:0031210	phosphatidylcholine binding	8/5114	30/18639	0.266666666666667	0.971920219006648	0.606337920882353	0.895806650409373
GO:0015370	solute:sodium symporter activity	21/5114	79/18639	0.265822784810127	0.968844522111058	0.609985298963689	0.895806650409373
GO:0042562	hormone binding	25/5114	94/18639	0.265957446808511	0.969335324807163	0.611416468236288	0.895806650409373
GO:0031406	carboxylic acid binding	50/5114	187/18639	0.267379679144385	0.974518936169768	0.612732357058307	0.895806650409373
GO:0016831	carboxy-lyase activity	9/5114	34/18639	0.264705882352941	0.96477374680807	0.61462630115986	0.895806650409373
GO:0001851	complement component C3b binding	3/5114	11/18639	0.272727272727273	0.994009314893163	0.617619570759026	0.895806650409373
GO:0005114	type II transforming growth factor beta receptor binding	3/5114	11/18639	0.272727272727273	0.994009314893163	0.617619570759026	0.895806650409373
GO:0005221	intracellularly cyclic nucleotide-activated monoatomic cation channel activity	3/5114	11/18639	0.272727272727273	0.994009314893163	0.617619570759026	0.895806650409373
GO:0008271	secondary active sulfate transmembrane transporter activity	3/5114	11/18639	0.272727272727273	0.994009314893163	0.617619570759026	0.895806650409373
GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives	3/5114	11/18639	0.272727272727273	0.994009314893163	0.617619570759026	0.895806650409373
GO:0019203	carbohydrate phosphatase activity	3/5114	11/18639	0.272727272727273	0.994009314893163	0.617619570759026	0.895806650409373
GO:0032129	histone H3K9 deacetylase activity, hydrolytic mechanism	3/5114	11/18639	0.272727272727273	0.994009314893163	0.617619570759026	0.895806650409373
GO:0034511	U3 snoRNA binding	3/5114	11/18639	0.272727272727273	0.994009314893163	0.617619570759026	0.895806650409373
GO:0043855	cyclic nucleotide-activated monoatomic ion channel activity	3/5114	11/18639	0.272727272727273	0.994009314893163	0.617619570759026	0.895806650409373
GO:0045294	alpha-catenin binding	3/5114	11/18639	0.272727272727273	0.994009314893163	0.617619570759026	0.895806650409373
GO:0048185	activin binding	3/5114	11/18639	0.272727272727273	0.994009314893163	0.617619570759026	0.895806650409373
GO:0050786	RAGE receptor binding	3/5114	11/18639	0.272727272727273	0.994009314893163	0.617619570759026	0.895806650409373
GO:0070697	activin receptor binding	3/5114	11/18639	0.272727272727273	0.994009314893163	0.617619570759026	0.895806650409373
GO:0070990	snRNP binding	3/5114	11/18639	0.272727272727273	0.994009314893163	0.617619570759026	0.895806650409373
GO:0097493	structural molecule activity conferring elasticity	3/5114	11/18639	0.272727272727273	0.994009314893163	0.617619570759026	0.895806650409373
GO:0004864	protein phosphatase inhibitor activity	14/5114	53/18639	0.264150943396226	0.962751160336774	0.617752463166639	0.895806650409373
GO:0000146	microfilament motor activity	10/5114	38/18639	0.263157894736842	0.95913179507235	0.622308863509047	0.899032314886228
GO:0042379	chemokine receptor binding	19/5114	72/18639	0.263888888888889	0.961796050058663	0.623183040444373	0.899032314886228
GO:0017081	chloride channel regulator activity	4/5114	15/18639	0.266666666666667	0.971920219006648	0.623267644361097	0.899032314886228
GO:0030553	cGMP binding	4/5114	15/18639	0.266666666666667	0.971920219006648	0.623267644361097	0.899032314886228
GO:0140161	monocarboxylate:sodium symporter activity	4/5114	15/18639	0.266666666666667	0.971920219006648	0.623267644361097	0.899032314886228
GO:0042577	lipid phosphatase activity	5/5114	19/18639	0.263157894736842	0.95913179507235	0.629355583779133	0.905900661161534
GO:0120227	acyl-CoA binding	5/5114	19/18639	0.263157894736842	0.95913179507235	0.629355583779133	0.905900661161534
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	16/5114	61/18639	0.262295081967213	0.955987100662277	0.63152628255158	0.908068317858378
GO:0016493	C-C chemokine receptor activity	6/5114	23/18639	0.260869565217391	0.95079151859346	0.635470761825873	0.911022593525464
GO:0016849	phosphorus-oxygen lyase activity	6/5114	23/18639	0.260869565217391	0.95079151859346	0.635470761825873	0.911022593525464
GO:0048306	calcium-dependent protein binding	21/5114	80/18639	0.2625	0.95673396558467	0.635784782229347	0.911022593525464
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	12/5114	46/18639	0.260869565217391	0.95079151859346	0.6362485755661	0.911022593525464
GO:0141108	transporter regulator activity	45/5114	170/18639	0.264705882352941	0.96477374680807	0.640132449399646	0.91465673250693
GO:0005044	scavenger receptor activity	7/5114	27/18639	0.259259259259259	0.944922435145353	0.641464970528286	0.91465673250693
GO:0016405	CoA-ligase activity	7/5114	27/18639	0.259259259259259	0.944922435145353	0.641464970528286	0.91465673250693
GO:0035255	ionotropic glutamate receptor binding	7/5114	27/18639	0.259259259259259	0.944922435145353	0.641464970528286	0.91465673250693
GO:0061134	peptidase regulator activity	60/5114	226/18639	0.265486725663717	0.967619687064141	0.643013860840813	0.915909211583472
GO:0016741	transferase activity, transferring one-carbon groups	57/5114	215/18639	0.265116279069767	0.966269520058935	0.645400366690383	0.918350938436524
GO:0016878	acid-thiol ligase activity	8/5114	31/18639	0.258064516129032	0.940567953877402	0.647283822124465	0.920072529679521
GO:0004521	RNA endonuclease activity	19/5114	73/18639	0.26027397260274	0.948620761701695	0.649797373071916	0.922685251160329
GO:0099106	ion channel regulator activity	42/5114	160/18639	0.2625	0.95673396558467	0.661266135311965	0.937995369507938
GO:0008200	ion channel inhibitor activity	11/5114	43/18639	0.255813953488372	0.932365326372657	0.663592063574829	0.940318214567652
GO:0003688	DNA replication origin binding	4/5114	16/18639	0.25	0.911175205318733	0.678235286742489	0.940378395796345
GO:0004198	calcium-dependent cysteine-type endopeptidase activity	4/5114	16/18639	0.25	0.911175205318733	0.678235286742489	0.940378395796345
GO:0005024	transforming growth factor beta receptor activity	4/5114	16/18639	0.25	0.911175205318733	0.678235286742489	0.940378395796345
GO:0008142	oxysterol binding	4/5114	16/18639	0.25	0.911175205318733	0.678235286742489	0.940378395796345
GO:0008296	3'-5'-DNA exonuclease activity	4/5114	16/18639	0.25	0.911175205318733	0.678235286742489	0.940378395796345
GO:0005326	neurotransmitter transmembrane transporter activity	5/5114	20/18639	0.25	0.911175205318733	0.678446444513371	0.940378395796345
GO:0010851	cyclase regulator activity	5/5114	20/18639	0.25	0.911175205318733	0.678446444513371	0.940378395796345
GO:0140664	ATP-dependent DNA damage sensor activity	5/5114	20/18639	0.25	0.911175205318733	0.678446444513371	0.940378395796345
GO:0030215	semaphorin receptor binding	6/5114	24/18639	0.25	0.911175205318733	0.680150343582258	0.940378395796345
GO:0050431	transforming growth factor beta binding	6/5114	24/18639	0.25	0.911175205318733	0.680150343582258	0.940378395796345
GO:0000995	RNA polymerase III general transcription initiation factor activity	3/5114	12/18639	0.25	0.911175205318733	0.680997220751608	0.940378395796345
GO:0004032	aldose reductase (NADPH) activity	3/5114	12/18639	0.25	0.911175205318733	0.680997220751608	0.940378395796345
GO:0004126	cytidine deaminase activity	3/5114	12/18639	0.25	0.911175205318733	0.680997220751608	0.940378395796345
GO:0004859	phospholipase inhibitor activity	3/5114	12/18639	0.25	0.911175205318733	0.680997220751608	0.940378395796345
GO:0005049	nuclear export signal receptor activity	3/5114	12/18639	0.25	0.911175205318733	0.680997220751608	0.940378395796345
GO:0005165	neurotrophin receptor binding	3/5114	12/18639	0.25	0.911175205318733	0.680997220751608	0.940378395796345
GO:0010853	cyclase activator activity	3/5114	12/18639	0.25	0.911175205318733	0.680997220751608	0.940378395796345
GO:0015166	polyol transmembrane transporter activity	3/5114	12/18639	0.25	0.911175205318733	0.680997220751608	0.940378395796345
GO:0016208	AMP binding	3/5114	12/18639	0.25	0.911175205318733	0.680997220751608	0.940378395796345
GO:0016801	hydrolase activity, acting on ether bonds	3/5114	12/18639	0.25	0.911175205318733	0.680997220751608	0.940378395796345
GO:0016803	ether hydrolase activity	3/5114	12/18639	0.25	0.911175205318733	0.680997220751608	0.940378395796345
GO:0045295	gamma-catenin binding	3/5114	12/18639	0.25	0.911175205318733	0.680997220751608	0.940378395796345
GO:0140829	bicarbonate:monoatomic anion antiporter activity	3/5114	12/18639	0.25	0.911175205318733	0.680997220751608	0.940378395796345
GO:0140900	chloride:bicarbonate antiporter activity	3/5114	12/18639	0.25	0.911175205318733	0.680997220751608	0.940378395796345
GO:0016866	intramolecular transferase activity	7/5114	28/18639	0.25	0.911175205318733	0.682671142514149	0.940378395796345
GO:0045499	chemorepellent activity	7/5114	28/18639	0.25	0.911175205318733	0.682671142514149	0.940378395796345
GO:0051393	alpha-actinin binding	7/5114	28/18639	0.25	0.911175205318733	0.682671142514149	0.940378395796345
GO:0015459	potassium channel regulator activity	15/5114	59/18639	0.254237288135593	0.926618852866508	0.682910225937023	0.940378395796345
GO:0015106	bicarbonate transmembrane transporter activity	8/5114	32/18639	0.25	0.911175205318733	0.685659785678898	0.942511112291357
GO:0008237	metallopeptidase activity	48/5114	184/18639	0.260869565217391	0.95079151859346	0.686528958074597	0.942511112291357
GO:0061135	endopeptidase regulator activity	48/5114	184/18639	0.260869565217391	0.95079151859346	0.686528958074597	0.942511112291357
GO:0004033	aldo-keto reductase (NADPH) activity	9/5114	36/18639	0.25	0.911175205318733	0.688920285257513	0.943896800061949
GO:0045505	dynein intermediate chain binding	9/5114	36/18639	0.25	0.911175205318733	0.688920285257513	0.943896800061949
GO:0050840	extracellular matrix binding	17/5114	67/18639	0.253731343283582	0.924774835248863	0.691700901613859	0.946677454108995
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	10/5114	40/18639	0.25	0.911175205318733	0.692335854066535	0.946677454108995
GO:0004620	phospholipase activity	28/5114	109/18639	0.256880733944954	0.936253421978882	0.693554607802939	0.947395594258815
GO:0140223	general transcription initiation factor activity	17/5114	68/18639	0.25	0.911175205318733	0.716789054425683	0.974443014702653
GO:0008276	protein methyltransferase activity	24/5114	95/18639	0.252631578947368	0.920766523269456	0.718945286617986	0.974443014702653
GO:0005537	D-mannose binding	6/5114	25/18639	0.24	0.874728197105983	0.721101163263058	0.974443014702653
GO:0015645	fatty acid ligase activity	6/5114	25/18639	0.24	0.874728197105983	0.721101163263058	0.974443014702653
GO:0120515	fatty acid-CoA ligase activity	6/5114	25/18639	0.24	0.874728197105983	0.721101163263058	0.974443014702653
GO:0001846	opsonin binding	5/5114	21/18639	0.238095238095238	0.867785909827364	0.722972031851545	0.974443014702653
GO:0008373	sialyltransferase activity	5/5114	21/18639	0.238095238095238	0.867785909827364	0.722972031851545	0.974443014702653
GO:0015125	bile acid transmembrane transporter activity	5/5114	21/18639	0.238095238095238	0.867785909827364	0.722972031851545	0.974443014702653
GO:0051428	peptide hormone receptor binding	5/5114	21/18639	0.238095238095238	0.867785909827364	0.722972031851545	0.974443014702653
GO:0017022	myosin binding	19/5114	76/18639	0.25	0.911175205318733	0.723461525220817	0.974443014702653
GO:0004029	aldehyde dehydrogenase (NAD+) activity	4/5114	17/18639	0.235294117647059	0.857576663829396	0.727324477627194	0.974443014702653
GO:0008569	minus-end-directed microtubule motor activity	4/5114	17/18639	0.235294117647059	0.857576663829396	0.727324477627194	0.974443014702653
GO:0016018	cyclosporin A binding	4/5114	17/18639	0.235294117647059	0.857576663829396	0.727324477627194	0.974443014702653
GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	4/5114	17/18639	0.235294117647059	0.857576663829396	0.727324477627194	0.974443014702653
GO:0030548	acetylcholine receptor regulator activity	4/5114	17/18639	0.235294117647059	0.857576663829396	0.727324477627194	0.974443014702653
GO:0031489	myosin V binding	4/5114	17/18639	0.235294117647059	0.857576663829396	0.727324477627194	0.974443014702653
GO:0015081	sodium ion transmembrane transporter activity	42/5114	164/18639	0.25609756097561	0.933398990814312	0.72785629963849	0.974443014702653
GO:0005544	calcium-dependent phospholipid binding	13/5114	53/18639	0.245283018867925	0.893983220312719	0.730581019948752	0.974443014702653
GO:0008146	sulfotransferase activity	13/5114	53/18639	0.245283018867925	0.893983220312719	0.730581019948752	0.974443014702653
GO:0016860	intramolecular oxidoreductase activity	13/5114	53/18639	0.245283018867925	0.893983220312719	0.730581019948752	0.974443014702653
GO:0038064	collagen receptor activity	13/5114	53/18639	0.245283018867925	0.893983220312719	0.730581019948752	0.974443014702653
GO:0016247	channel regulator activity	43/5114	168/18639	0.255952380952381	0.932869853064417	0.731132598095535	0.974443014702653
GO:0002161	aminoacyl-tRNA editing activity	3/5114	13/18639	0.230769230769231	0.8410848049096	0.736182423992048	0.974443014702653
GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	3/5114	13/18639	0.230769230769231	0.8410848049096	0.736182423992048	0.974443014702653
GO:0004465	lipoprotein lipase activity	3/5114	13/18639	0.230769230769231	0.8410848049096	0.736182423992048	0.974443014702653
GO:0005338	nucleotide-sugar transmembrane transporter activity	3/5114	13/18639	0.230769230769231	0.8410848049096	0.736182423992048	0.974443014702653
GO:0008253	5'-nucleotidase activity	3/5114	13/18639	0.230769230769231	0.8410848049096	0.736182423992048	0.974443014702653
GO:0009982	pseudouridine synthase activity	3/5114	13/18639	0.230769230769231	0.8410848049096	0.736182423992048	0.974443014702653
GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors	3/5114	13/18639	0.230769230769231	0.8410848049096	0.736182423992048	0.974443014702653
GO:0019104	DNA N-glycosylase activity	3/5114	13/18639	0.230769230769231	0.8410848049096	0.736182423992048	0.974443014702653
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	3/5114	13/18639	0.230769230769231	0.8410848049096	0.736182423992048	0.974443014702653
GO:0089720	caspase binding	3/5114	13/18639	0.230769230769231	0.8410848049096	0.736182423992048	0.974443014702653
GO:0004520	DNA endonuclease activity	10/5114	42/18639	0.238095238095238	0.867785909827364	0.753743554009038	0.995298834190831
GO:0140101	catalytic activity, acting on a tRNA	35/5114	139/18639	0.251798561151079	0.917730422623184	0.753797186176592	0.995298834190831
GO:0051427	hormone receptor binding	8/5114	34/18639	0.235294117647059	0.857576663829396	0.754124665730242	0.995298834190831
GO:0022839	monoatomic ion-gated channel activity	7/5114	30/18639	0.233333333333333	0.850430191630817	0.755537505024602	0.996200996007342
GO:0050750	low-density lipoprotein particle receptor binding	6/5114	26/18639	0.230769230769231	0.8410848049096	0.758242681113123	0.998803763163477
GO:0008970	phospholipase A1 activity	5/5114	22/18639	0.227272727272727	0.828341095744302	0.762880973060808	1
GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity	4/5114	18/18639	0.222222222222222	0.809933515838874	0.770575868083107	1
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	4/5114	18/18639	0.222222222222222	0.809933515838874	0.770575868083107	1
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	4/5114	18/18639	0.222222222222222	0.809933515838874	0.770575868083107	1
GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	4/5114	18/18639	0.222222222222222	0.809933515838874	0.770575868083107	1
GO:1901611	phosphatidylglycerol binding	4/5114	18/18639	0.222222222222222	0.809933515838874	0.770575868083107	1
GO:0016209	antioxidant activity	21/5114	86/18639	0.244186046511628	0.889985084264809	0.770854632252995	1
GO:0005507	copper ion binding	15/5114	63/18639	0.238095238095238	0.867785909827364	0.782119028630427	1
GO:0005313	L-glutamate transmembrane transporter activity	3/5114	14/18639	0.214285714285714	0.781007318844628	0.783505151183409	1
GO:0008195	phosphatidate phosphatase activity	3/5114	14/18639	0.214285714285714	0.781007318844628	0.783505151183409	1
GO:0008331	high voltage-gated calcium channel activity	3/5114	14/18639	0.214285714285714	0.781007318844628	0.783505151183409	1
GO:0015926	glucosidase activity	3/5114	14/18639	0.214285714285714	0.781007318844628	0.783505151183409	1
GO:0016530	metallochaperone activity	3/5114	14/18639	0.214285714285714	0.781007318844628	0.783505151183409	1
GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters	3/5114	14/18639	0.214285714285714	0.781007318844628	0.783505151183409	1
GO:0030283	testosterone dehydrogenase [NAD(P)+] activity	3/5114	14/18639	0.214285714285714	0.781007318844628	0.783505151183409	1
GO:0042043	neurexin family protein binding	3/5114	14/18639	0.214285714285714	0.781007318844628	0.783505151183409	1
GO:0043176	amine binding	3/5114	14/18639	0.214285714285714	0.781007318844628	0.783505151183409	1
GO:0016229	steroid dehydrogenase activity	8/5114	35/18639	0.228571428571429	0.83307447343427	0.78411403017167	1
GO:0046982	protein heterodimerization activity	95/5114	369/18639	0.257452574525745	0.938337609813329	0.785649405863894	1
GO:0033293	monocarboxylic acid binding	19/5114	79/18639	0.240506329113924	0.876573615243338	0.786799665920374	1
GO:0008509	monoatomic anion transmembrane transporter activity	37/5114	149/18639	0.248322147651007	0.905059935484379	0.788952434393608	1
GO:0004022	alcohol dehydrogenase (NAD+) activity	5/5114	23/18639	0.217391304347826	0.79232626549455	0.798272698403846	1
GO:0008171	O-methyltransferase activity	5/5114	23/18639	0.217391304347826	0.79232626549455	0.798272698403846	1
GO:0017134	fibroblast growth factor binding	5/5114	23/18639	0.217391304347826	0.79232626549455	0.798272698403846	1
GO:0140103	catalytic activity, acting on a glycoprotein	5/5114	23/18639	0.217391304347826	0.79232626549455	0.798272698403846	1
GO:0003777	microtubule motor activity	16/5114	68/18639	0.235294117647059	0.857576663829396	0.803499410021705	1
GO:0004090	carbonyl reductase (NADPH) activity	2/5114	10/18639	0.2	0.728940164254986	0.80657585501988	1
GO:0008519	ammonium channel activity	2/5114	10/18639	0.2	0.728940164254986	0.80657585501988	1
GO:0015279	store-operated calcium channel activity	2/5114	10/18639	0.2	0.728940164254986	0.80657585501988	1
GO:0016175	superoxide-generating NAD(P)H oxidase activity	2/5114	10/18639	0.2	0.728940164254986	0.80657585501988	1
GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor	2/5114	10/18639	0.2	0.728940164254986	0.80657585501988	1
GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines	2/5114	10/18639	0.2	0.728940164254986	0.80657585501988	1
GO:0016868	intramolecular phosphotransferase activity	2/5114	10/18639	0.2	0.728940164254986	0.80657585501988	1
GO:0019531	oxalate transmembrane transporter activity	2/5114	10/18639	0.2	0.728940164254986	0.80657585501988	1
GO:0031434	mitogen-activated protein kinase kinase binding	2/5114	10/18639	0.2	0.728940164254986	0.80657585501988	1
GO:0031956	medium-chain fatty acid-CoA ligase activity	2/5114	10/18639	0.2	0.728940164254986	0.80657585501988	1
GO:0043295	glutathione binding	2/5114	10/18639	0.2	0.728940164254986	0.80657585501988	1
GO:0047429	nucleoside triphosphate diphosphatase activity	2/5114	10/18639	0.2	0.728940164254986	0.80657585501988	1
GO:0050308	sugar-phosphatase activity	2/5114	10/18639	0.2	0.728940164254986	0.80657585501988	1
GO:0070739	protein-glutamic acid ligase activity	2/5114	10/18639	0.2	0.728940164254986	0.80657585501988	1
GO:0070740	tubulin-glutamic acid ligase activity	2/5114	10/18639	0.2	0.728940164254986	0.80657585501988	1
GO:0072582	17-beta-hydroxysteroid dehydrogenase (NADP+) activity	2/5114	10/18639	0.2	0.728940164254986	0.80657585501988	1
GO:0140135	mechanosensitive monoatomic cation channel activity	2/5114	10/18639	0.2	0.728940164254986	0.80657585501988	1
GO:1990763	arrestin family protein binding	2/5114	10/18639	0.2	0.728940164254986	0.80657585501988	1
GO:0005262	calcium channel activity	32/5114	131/18639	0.244274809160305	0.890308597563342	0.807711924675075	1
GO:0008574	plus-end-directed microtubule motor activity	4/5114	19/18639	0.210526315789474	0.76730543605788	0.808234610564166	1
GO:0022840	leak channel activity	4/5114	19/18639	0.210526315789474	0.76730543605788	0.808234610564166	1
GO:0022842	narrow pore channel activity	4/5114	19/18639	0.210526315789474	0.76730543605788	0.808234610564166	1
GO:0034987	immunoglobulin receptor binding	4/5114	19/18639	0.210526315789474	0.76730543605788	0.808234610564166	1
GO:0043395	heparan sulfate proteoglycan binding	4/5114	19/18639	0.210526315789474	0.76730543605788	0.808234610564166	1
GO:0016874	ligase activity	41/5114	167/18639	0.245508982035928	0.89480678845672	0.822528518521589	1
GO:0019838	growth factor binding	33/5114	136/18639	0.242647058823529	0.884375934574064	0.822972948277071	1
GO:0004089	carbonate dehydratase activity	3/5114	15/18639	0.2	0.728940164254986	0.823564527888988	1
GO:0005523	tropomyosin binding	3/5114	15/18639	0.2	0.728940164254986	0.823564527888988	1
GO:0008252	nucleotidase activity	3/5114	15/18639	0.2	0.728940164254986	0.823564527888988	1
GO:0015116	sulfate transmembrane transporter activity	3/5114	15/18639	0.2	0.728940164254986	0.823564527888988	1
GO:0015556	C4-dicarboxylate transmembrane transporter activity	3/5114	15/18639	0.2	0.728940164254986	0.823564527888988	1
GO:0016846	carbon-sulfur lyase activity	3/5114	15/18639	0.2	0.728940164254986	0.823564527888988	1
GO:0031005	filamin binding	3/5114	15/18639	0.2	0.728940164254986	0.823564527888988	1
GO:0031386	protein tag activity	3/5114	15/18639	0.2	0.728940164254986	0.823564527888988	1
GO:0141047	molecular tag activity	3/5114	15/18639	0.2	0.728940164254986	0.823564527888988	1
GO:0017046	peptide hormone binding	12/5114	53/18639	0.226415094339623	0.825215280288664	0.82513700539056	1
GO:0004806	triacylglycerol lipase activity	5/5114	24/18639	0.208333333333333	0.759312671098944	0.829357528620053	1
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	5/5114	24/18639	0.208333333333333	0.759312671098944	0.829357528620053	1
GO:0008028	monocarboxylic acid transmembrane transporter activity	16/5114	70/18639	0.228571428571429	0.83307447343427	0.840094580825797	1
GO:0004745	all-trans-retinol dehydrogenase (NAD+) activity	4/5114	20/18639	0.2	0.728940164254986	0.840681652076865	1
GO:0016408	C-acyltransferase activity	4/5114	20/18639	0.2	0.728940164254986	0.840681652076865	1
GO:0004866	endopeptidase inhibitor activity	39/5114	161/18639	0.242236024844721	0.882877838693928	0.843013075968867	1
GO:0015103	inorganic anion transmembrane transporter activity	40/5114	165/18639	0.242424242424242	0.88356383546059	0.844223232974996	1
GO:0048020	CCR chemokine receptor binding	11/5114	50/18639	0.22	0.801834180680485	0.846932172783376	1
GO:0004181	metallocarboxypeptidase activity	6/5114	29/18639	0.206896551724138	0.754076031987917	0.847559493380256	1
GO:0004016	adenylate cyclase activity	2/5114	11/18639	0.181818181818182	0.662672876595442	0.848566140411181	1
GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity	2/5114	11/18639	0.181818181818182	0.662672876595442	0.848566140411181	1
GO:0019215	intermediate filament binding	2/5114	11/18639	0.181818181818182	0.662672876595442	0.848566140411181	1
GO:0031731	CCR6 chemokine receptor binding	2/5114	11/18639	0.181818181818182	0.662672876595442	0.848566140411181	1
GO:0035252	UDP-xylosyltransferase activity	2/5114	11/18639	0.181818181818182	0.662672876595442	0.848566140411181	1
GO:0042285	xylosyltransferase activity	2/5114	11/18639	0.181818181818182	0.662672876595442	0.848566140411181	1
GO:0048407	platelet-derived growth factor binding	2/5114	11/18639	0.181818181818182	0.662672876595442	0.848566140411181	1
GO:1900750	oligopeptide binding	2/5114	11/18639	0.181818181818182	0.662672876595442	0.848566140411181	1
GO:0031492	nucleosomal DNA binding	9/5114	42/18639	0.214285714285714	0.781007318844628	0.853262579777298	1
GO:0140299	molecular sensor activity	16/5114	71/18639	0.225352112676056	0.821341030146464	0.856348805999932	1
GO:0022841	potassium ion leak channel activity	3/5114	16/18639	0.1875	0.68338140398905	0.857102045076641	1
GO:0005109	frizzled binding	8/5114	38/18639	0.210526315789474	0.76730543605788	0.857727683086227	1
GO:0005010	insulin-like growth factor receptor activity	11/5114	51/18639	0.215686274509804	0.786111941843613	0.865211611965183	1
GO:0005021	vascular endothelial growth factor receptor activity	11/5114	51/18639	0.215686274509804	0.786111941843613	0.865211611965183	1
GO:0009975	cyclase activity	4/5114	21/18639	0.19047619047619	0.694228727861892	0.868378033306352	1
GO:0001965	G-protein alpha-subunit binding	6/5114	30/18639	0.2	0.728940164254986	0.87056499046917	1
GO:0033612	receptor serine/threonine kinase binding	6/5114	30/18639	0.2	0.728940164254986	0.87056499046917	1
GO:0005125	cytokine activity	57/5114	234/18639	0.243589743589744	0.887811738515688	0.872697490881941	1
GO:0004714	transmembrane receptor protein tyrosine kinase activity	13/5114	60/18639	0.216666666666667	0.789685177942902	0.876354051047906	1
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	8/5114	39/18639	0.205128205128205	0.747630937697422	0.877220900669455	1
GO:0170055	lipid transmembrane transporter activity	12/5114	56/18639	0.214285714285714	0.781007318844628	0.878786712223554	1
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	11/5114	52/18639	0.211538461538462	0.770994404500466	0.881707187534131	1
GO:0003720	telomerase activity	2/5114	12/18639	0.166666666666667	0.607450136879155	0.882079924343096	1
GO:0004300	enoyl-CoA hydratase activity	2/5114	12/18639	0.166666666666667	0.607450136879155	0.882079924343096	1
GO:0005436	sodium:phosphate symporter activity	2/5114	12/18639	0.166666666666667	0.607450136879155	0.882079924343096	1
GO:0008179	adenylate cyclase binding	2/5114	12/18639	0.166666666666667	0.607450136879155	0.882079924343096	1
GO:0016273	arginine N-methyltransferase activity	2/5114	12/18639	0.166666666666667	0.607450136879155	0.882079924343096	1
GO:0016274	protein-arginine N-methyltransferase activity	2/5114	12/18639	0.166666666666667	0.607450136879155	0.882079924343096	1
GO:0070679	inositol 1,4,5 trisphosphate binding	2/5114	12/18639	0.166666666666667	0.607450136879155	0.882079924343096	1
GO:1902282	voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	2/5114	12/18639	0.166666666666667	0.607450136879155	0.882079924343096	1
GO:0004623	phospholipase A2 activity	7/5114	35/18639	0.2	0.728940164254986	0.883192853656689	1
GO:0030414	peptidase inhibitor activity	40/5114	169/18639	0.236686390532544	0.862651081958564	0.884077396990041	1
GO:0004549	tRNA-specific ribonuclease activity	3/5114	17/18639	0.176470588235294	0.643182497872047	0.884911523815809	1
GO:0009881	photoreceptor activity	3/5114	17/18639	0.176470588235294	0.643182497872047	0.884911523815809	1
GO:0045125	bioactive lipid receptor activity	3/5114	17/18639	0.176470588235294	0.643182497872047	0.884911523815809	1
GO:0048038	quinone binding	3/5114	17/18639	0.176470588235294	0.643182497872047	0.884911523815809	1
GO:0070492	oligosaccharide binding	3/5114	17/18639	0.176470588235294	0.643182497872047	0.884911523815809	1
GO:0005310	dicarboxylic acid transmembrane transporter activity	6/5114	31/18639	0.193548387096774	0.705425965408051	0.890593829172857	1
GO:0047499	calcium-independent phospholipase A2 activity	6/5114	31/18639	0.193548387096774	0.705425965408051	0.890593829172857	1
GO:0003823	antigen binding	41/5114	174/18639	0.235632183908046	0.858808814208461	0.893161949314627	1
GO:0019199	transmembrane receptor protein kinase activity	17/5114	78/18639	0.217948717948718	0.794357871303511	0.895976877934706	1
GO:0005003	ephrin receptor activity	11/5114	53/18639	0.207547169811321	0.756447340264608	0.896523187619352	1
GO:0005005	transmembrane-ephrin receptor activity	11/5114	53/18639	0.207547169811321	0.756447340264608	0.896523187619352	1
GO:0016782	transferase activity, transferring sulphur-containing groups	15/5114	70/18639	0.214285714285714	0.781007318844628	0.899287502429743	1
GO:0005004	GPI-linked ephrin receptor activity	10/5114	49/18639	0.204081632653061	0.743816494137741	0.900191811490368	1
GO:0005008	hepatocyte growth factor receptor activity	10/5114	49/18639	0.204081632653061	0.743816494137741	0.900191811490368	1
GO:0005009	insulin receptor activity	10/5114	49/18639	0.204081632653061	0.743816494137741	0.900191811490368	1
GO:0005011	macrophage colony-stimulating factor receptor activity	10/5114	49/18639	0.204081632653061	0.743816494137741	0.900191811490368	1
GO:0005018	platelet-derived growth factor alpha-receptor activity	10/5114	49/18639	0.204081632653061	0.743816494137741	0.900191811490368	1
GO:0005020	stem cell factor receptor activity	10/5114	49/18639	0.204081632653061	0.743816494137741	0.900191811490368	1
GO:0008288	boss receptor activity	10/5114	49/18639	0.204081632653061	0.743816494137741	0.900191811490368	1
GO:0036332	placental growth factor receptor activity	10/5114	49/18639	0.204081632653061	0.743816494137741	0.900191811490368	1
GO:0038062	protein tyrosine kinase collagen receptor activity	10/5114	49/18639	0.204081632653061	0.743816494137741	0.900191811490368	1
GO:0060175	brain-derived neurotrophic factor receptor activity	10/5114	49/18639	0.204081632653061	0.743816494137741	0.900191811490368	1
GO:0004869	cysteine-type endopeptidase inhibitor activity	7/5114	36/18639	0.194444444444444	0.708691826359015	0.900543345883131	1
GO:0055106	ubiquitin-protein transferase regulator activity	7/5114	36/18639	0.194444444444444	0.708691826359015	0.900543345883131	1
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	7/5114	36/18639	0.194444444444444	0.708691826359015	0.900543345883131	1
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	7/5114	36/18639	0.194444444444444	0.708691826359015	0.900543345883131	1
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	7/5114	36/18639	0.194444444444444	0.708691826359015	0.900543345883131	1
GO:0004867	serine-type endopeptidase inhibitor activity	21/5114	95/18639	0.221052631578947	0.805670707860774	0.902525990965874	1
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	30/5114	132/18639	0.227272727272727	0.828341095744302	0.907770999507201	1
GO:0015280	ligand-gated sodium channel activity	3/5114	18/18639	0.166666666666667	0.607450136879155	0.907778654962349	1
GO:0047498	calcium-dependent phospholipase A2 activity	6/5114	32/18639	0.1875	0.68338140398905	0.907919026353335	1
GO:0003964	RNA-directed DNA polymerase activity	2/5114	13/18639	0.153846153846154	0.560723203273066	0.908606742588741	1
GO:0005542	folic acid binding	2/5114	13/18639	0.153846153846154	0.560723203273066	0.908606742588741	1
GO:0070700	BMP receptor binding	2/5114	13/18639	0.153846153846154	0.560723203273066	0.908606742588741	1
GO:0005212	structural constituent of eye lens	4/5114	23/18639	0.173913043478261	0.63386101239564	0.911516377328487	1
GO:0031681	G-protein beta-subunit binding	4/5114	23/18639	0.173913043478261	0.63386101239564	0.911516377328487	1
GO:0005006	epidermal growth factor receptor activity	10/5114	50/18639	0.2	0.728940164254986	0.913506721167115	1
GO:0005007	fibroblast growth factor receptor activity	10/5114	50/18639	0.2	0.728940164254986	0.913506721167115	1
GO:0005017	platelet-derived growth factor receptor activity	10/5114	50/18639	0.2	0.728940164254986	0.913506721167115	1
GO:0005019	platelet-derived growth factor beta-receptor activity	10/5114	50/18639	0.2	0.728940164254986	0.913506721167115	1
GO:0070001	aspartic-type peptidase activity	7/5114	37/18639	0.189189189189189	0.689537993214176	0.915648151113775	1
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	12/5114	59/18639	0.203389830508475	0.741295082293207	0.918310013996508	1
GO:0070888	E-box binding	12/5114	59/18639	0.203389830508475	0.741295082293207	0.918310013996508	1
GO:0051536	iron-sulfur cluster binding	16/5114	76/18639	0.210526315789474	0.76730543605788	0.919202993267048	1
GO:0008083	growth factor activity	37/5114	162/18639	0.228395061728395	0.83243166905662	0.922222756914958	1
GO:0005506	iron ion binding	35/5114	154/18639	0.227272727272727	0.828341095744302	0.922343428983454	1
GO:0016859	cis-trans isomerase activity	8/5114	42/18639	0.19047619047619	0.694228727861892	0.922871553424151	1
GO:0042056	chemoattractant activity	8/5114	42/18639	0.19047619047619	0.694228727861892	0.922871553424151	1
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	27/5114	122/18639	0.221311475409836	0.806614116183796	0.924701552346214	1
GO:0005030	neurotrophin receptor activity	10/5114	51/18639	0.196078431372549	0.71464721985783	0.925286016094416	1
GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)+] activity	3/5114	19/18639	0.157894736842105	0.57547907704341	0.926443163287009	1
GO:0005229	intracellularly calcium-gated chloride channel activity	3/5114	19/18639	0.157894736842105	0.57547907704341	0.926443163287009	1
GO:0008301	DNA binding, bending	3/5114	19/18639	0.157894736842105	0.57547907704341	0.926443163287009	1
GO:0008381	mechanosensitive monoatomic ion channel activity	3/5114	19/18639	0.157894736842105	0.57547907704341	0.926443163287009	1
GO:0141147	intracellularly calcium-gated channel activity	3/5114	19/18639	0.157894736842105	0.57547907704341	0.926443163287009	1
GO:0001664	G protein-coupled receptor binding	71/5114	297/18639	0.239057239057239	0.871292115523637	0.926719691516607	1
GO:0005540	hyaluronic acid binding	4/5114	24/18639	0.166666666666667	0.607450136879155	0.927948147070174	1
GO:0051540	metal cluster binding	16/5114	77/18639	0.207792207792208	0.757340430394791	0.928527901673266	1
GO:0031404	chloride ion binding	2/5114	14/18639	0.142857142857143	0.520671545896419	0.929457007822962	1
GO:0032036	myosin heavy chain binding	2/5114	14/18639	0.142857142857143	0.520671545896419	0.929457007822962	1
GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization	2/5114	14/18639	0.142857142857143	0.520671545896419	0.929457007822962	1
GO:1901612	cardiolipin binding	2/5114	14/18639	0.142857142857143	0.520671545896419	0.929457007822962	1
GO:0003785	actin monomer binding	5/5114	29/18639	0.172413793103448	0.628396693323264	0.931359121648936	1
GO:0046873	metal ion transmembrane transporter activity	110/5114	450/18639	0.244444444444444	0.890926867422761	0.93370164811685	1
GO:1901681	sulfur compound binding	65/5114	275/18639	0.236363636363636	0.861474739574075	0.933791894756376	1
GO:0005245	voltage-gated calcium channel activity	8/5114	43/18639	0.186046511627907	0.678083873725569	0.934413748874658	1
GO:0004601	peroxidase activity	11/5114	57/18639	0.192982456140351	0.70336331638639	0.941256490379305	1
GO:0000030	mannosyltransferase activity	4/5114	25/18639	0.16	0.583152131403989	0.941572247472245	1
GO:0001848	complement binding	4/5114	25/18639	0.16	0.583152131403989	0.941572247472245	1
GO:0001972	retinoic acid binding	3/5114	20/18639	0.15	0.54670512319124	0.94157754761821	1
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	3/5114	20/18639	0.15	0.54670512319124	0.94157754761821	1
GO:0015108	chloride transmembrane transporter activity	26/5114	121/18639	0.214876033057851	0.78315885415825	0.945203663267245	1
GO:0004865	protein serine/threonine phosphatase inhibitor activity	2/5114	15/18639	0.133333333333333	0.485960109503324	0.945748158582036	1
GO:0045504	dynein heavy chain binding	2/5114	15/18639	0.133333333333333	0.485960109503324	0.945748158582036	1
GO:0051371	muscle alpha-actinin binding	2/5114	15/18639	0.133333333333333	0.485960109503324	0.945748158582036	1
GO:0098631	cell adhesion mediator activity	15/5114	76/18639	0.197368421052632	0.719348846304263	0.953150487823753	1
GO:0061891	calcium ion sensor activity	3/5114	21/18639	0.142857142857143	0.520671545896419	0.953777466670187	1
GO:0004497	monooxygenase activity	22/5114	106/18639	0.207547169811321	0.756447340264608	0.954413863753617	1
GO:0004190	aspartic-type endopeptidase activity	6/5114	36/18639	0.166666666666667	0.607450136879155	0.955554052951587	1
GO:0046906	tetrapyrrole binding	33/5114	152/18639	0.217105263157895	0.791283730934689	0.956240911963702	1
GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	2/5114	16/18639	0.125	0.455587602659366	0.958411889082806	1
GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	2/5114	16/18639	0.125	0.455587602659366	0.958411889082806	1
GO:0099507	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	2/5114	16/18639	0.125	0.455587602659366	0.958411889082806	1
GO:0001164	RNA polymerase I core promoter sequence-specific DNA binding	1/5114	10/18639	0.1	0.364470082127493	0.959565690058907	1
GO:0008401	retinoic acid 4-hydroxylase activity	1/5114	10/18639	0.1	0.364470082127493	0.959565690058907	1
GO:0016783	sulfurtransferase activity	1/5114	10/18639	0.1	0.364470082127493	0.959565690058907	1
GO:0016889	DNA endonuclease activity, producing 3'-phosphomonoesters	1/5114	10/18639	0.1	0.364470082127493	0.959565690058907	1
GO:0031957	very long-chain fatty acid-CoA ligase activity	1/5114	10/18639	0.1	0.364470082127493	0.959565690058907	1
GO:0042166	acetylcholine binding	1/5114	10/18639	0.1	0.364470082127493	0.959565690058907	1
GO:0097177	mitochondrial ribosome binding	1/5114	10/18639	0.1	0.364470082127493	0.959565690058907	1
GO:0140940	histone H2A methyltransferase activity	1/5114	10/18639	0.1	0.364470082127493	0.959565690058907	1
GO:0141109	transporter activator activity	1/5114	10/18639	0.1	0.364470082127493	0.959565690058907	1
GO:1990259	histone H2AQ104 methyltransferase activity	1/5114	10/18639	0.1	0.364470082127493	0.959565690058907	1
GO:0098632	cell-cell adhesion mediator activity	10/5114	55/18639	0.181818181818182	0.662672876595442	0.95963956586884	1
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	8/5114	46/18639	0.173913043478261	0.63386101239564	0.960453392860638	1
GO:0005253	monoatomic anion channel activity	21/5114	103/18639	0.203883495145631	0.743094342201685	0.960558497792324	1
GO:0008395	steroid hydroxylase activity	4/5114	27/18639	0.148148148148148	0.539955677225916	0.962015019902528	1
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	5/5114	32/18639	0.15625	0.569484503324208	0.962172817960426	1
GO:0016597	amino acid binding	9/5114	51/18639	0.176470588235294	0.643182497872047	0.96306612267893	1
GO:0030021	extracellular matrix structural constituent conferring compression resistance	3/5114	22/18639	0.136363636363636	0.497004657446582	0.963559936490949	1
GO:0140784	metal ion sensor activity	3/5114	22/18639	0.136363636363636	0.497004657446582	0.963559936490949	1
GO:0005504	fatty acid binding	8/5114	47/18639	0.170212765957447	0.620374607876584	0.96679419317084	1
GO:0004550	nucleoside diphosphate kinase activity	2/5114	17/18639	0.117647058823529	0.428788331914698	0.968211937785072	1
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	2/5114	17/18639	0.117647058823529	0.428788331914698	0.968211937785072	1
GO:0015347	sodium-independent organic anion transmembrane transporter activity	2/5114	17/18639	0.117647058823529	0.428788331914698	0.968211937785072	1
GO:0019198	transmembrane receptor protein phosphatase activity	2/5114	17/18639	0.117647058823529	0.428788331914698	0.968211937785072	1
GO:0001163	RNA polymerase I transcription regulatory region sequence-specific DNA binding	1/5114	11/18639	0.0909090909090909	0.331336438297721	0.97066564502368	1
GO:0008046	axon guidance receptor activity	1/5114	11/18639	0.0909090909090909	0.331336438297721	0.97066564502368	1
GO:0015217	ADP transmembrane transporter activity	1/5114	11/18639	0.0909090909090909	0.331336438297721	0.97066564502368	1
GO:0016725	oxidoreductase activity, acting on CH or CH2 groups	1/5114	11/18639	0.0909090909090909	0.331336438297721	0.97066564502368	1
GO:0050998	nitric-oxide synthase binding	1/5114	11/18639	0.0909090909090909	0.331336438297721	0.97066564502368	1
GO:0098973	structural constituent of postsynaptic actin cytoskeleton	1/5114	11/18639	0.0909090909090909	0.331336438297721	0.97066564502368	1
GO:0099508	voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	1/5114	11/18639	0.0909090909090909	0.331336438297721	0.97066564502368	1
GO:0099528	G protein-coupled neurotransmitter receptor activity	1/5114	11/18639	0.0909090909090909	0.331336438297721	0.97066564502368	1
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	7/5114	43/18639	0.162790697674419	0.593323389509873	0.970830439011156	1
GO:0004175	endopeptidase activity	95/5114	405/18639	0.234567901234568	0.854929822274367	0.970865235535849	1
GO:0004602	glutathione peroxidase activity	3/5114	23/18639	0.130434782608696	0.47539575929673	0.971366470365318	1
GO:0099186	structural constituent of postsynapse	3/5114	23/18639	0.130434782608696	0.47539575929673	0.971366470365318	1
GO:0004222	metalloendopeptidase activity	22/5114	110/18639	0.2	0.728940164254986	0.971804119365403	1
GO:0016500	protein-hormone receptor activity	12/5114	67/18639	0.17910447761194	0.652782236646256	0.974753875154986	1
GO:0016891	RNA endonuclease activity, producing 5'-phosphomonoesters	5/5114	34/18639	0.147058823529412	0.535985414893372	0.97500230602935	1
GO:0004970	glutamate-gated receptor activity	2/5114	18/18639	0.111111111111111	0.404966757919437	0.975766098137913	1
GO:0003995	acyl-CoA dehydrogenase activity	1/5114	12/18639	0.0833333333333333	0.303725068439578	0.978718892358278	1
GO:0004526	ribonuclease P activity	1/5114	12/18639	0.0833333333333333	0.303725068439578	0.978718892358278	1
GO:0036009	protein-glutamine N-methyltransferase activity	1/5114	12/18639	0.0833333333333333	0.303725068439578	0.978718892358278	1
GO:0052890	oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor	1/5114	12/18639	0.0833333333333333	0.303725068439578	0.978718892358278	1
GO:0005539	glycosaminoglycan binding	53/5114	242/18639	0.21900826446281	0.798219601353601	0.979942622072403	1
GO:0098918	structural constituent of synapse	4/5114	30/18639	0.133333333333333	0.485960109503324	0.980581959818963	1
GO:0015245	fatty acid transmembrane transporter activity	2/5114	19/18639	0.105263157894737	0.38365271802894	0.981568796355666	1
GO:0016918	retinal binding	2/5114	19/18639	0.105263157894737	0.38365271802894	0.981568796355666	1
GO:0070003	threonine-type peptidase activity	2/5114	19/18639	0.105263157894737	0.38365271802894	0.981568796355666	1
GO:0005251	delayed rectifier potassium channel activity	3/5114	25/18639	0.12	0.437364098552992	0.982477748048001	1
GO:0015271	outward rectifier potassium channel activity	3/5114	25/18639	0.12	0.437364098552992	0.982477748048001	1
GO:0004812	aminoacyl-tRNA ligase activity	6/5114	41/18639	0.146341463414634	0.533370851893892	0.983402291400887	1
GO:0016875	ligase activity, forming carbon-oxygen bonds	6/5114	41/18639	0.146341463414634	0.533370851893892	0.983402291400887	1
GO:0005231	excitatory extracellular ligand-gated monoatomic ion channel activity	5/5114	36/18639	0.138888888888889	0.506208447399296	0.983677837994635	1
GO:0004993	G protein-coupled serotonin receptor activity	1/5114	13/18639	0.0769230769230769	0.280361601636533	0.98456157150574	1
GO:0039706	co-receptor binding	1/5114	13/18639	0.0769230769230769	0.280361601636533	0.98456157150574	1
GO:0045159	myosin II binding	1/5114	13/18639	0.0769230769230769	0.280361601636533	0.98456157150574	1
GO:0071837	HMG box domain binding	1/5114	13/18639	0.0769230769230769	0.280361601636533	0.98456157150574	1
GO:0015464	acetylcholine receptor activity	2/5114	20/18639	0.1	0.364470082127493	0.986012268437606	1
GO:0140939	histone H4 methyltransferase activity	2/5114	20/18639	0.1	0.364470082127493	0.986012268437606	1
GO:0022829	wide pore channel activity	5/5114	37/18639	0.135135135135135	0.492527138010126	0.986865347698807	1
GO:0020037	heme binding	28/5114	142/18639	0.197183098591549	0.718673401378155	0.98699573050491	1
GO:0008201	heparin binding	35/5114	172/18639	0.203488372093023	0.741654236887341	0.987306615339879	1
GO:0017171	serine hydrolase activity	41/5114	198/18639	0.207070707070707	0.754710776122587	0.988334039920679	1
GO:0005344	oxygen carrier activity	1/5114	14/18639	0.0714285714285714	0.260335772948209	0.988800384096723	1
GO:0008392	arachidonate epoxygenase activity	1/5114	14/18639	0.0714285714285714	0.260335772948209	0.988800384096723	1
GO:0005104	fibroblast growth factor receptor binding	3/5114	27/18639	0.111111111111111	0.404966757919437	0.989389887696426	1
GO:0005248	voltage-gated sodium channel activity	2/5114	21/18639	0.0952380952380952	0.347114363930946	0.989405405465755	1
GO:1904047	S-adenosyl-L-methionine binding	2/5114	21/18639	0.0952380952380952	0.347114363930946	0.989405405465755	1
GO:0005501	retinoid binding	5/5114	38/18639	0.131578947368421	0.479565897536175	0.989457665130005	1
GO:0019840	isoprenoid binding	5/5114	38/18639	0.131578947368421	0.479565897536175	0.989457665130005	1
GO:0030020	extracellular matrix structural constituent conferring tensile strength	6/5114	44/18639	0.136363636363636	0.497004657446582	0.991107966182595	1
GO:0030547	signaling receptor inhibitor activity	6/5114	44/18639	0.136363636363636	0.497004657446582	0.991107966182595	1
GO:0008020	G protein-coupled photoreceptor activity	1/5114	15/18639	0.0666666666666667	0.242980054751662	0.991875543062057	1
GO:0008242	omega peptidase activity	1/5114	15/18639	0.0666666666666667	0.242980054751662	0.991875543062057	1
GO:0015250	water channel activity	1/5114	15/18639	0.0666666666666667	0.242980054751662	0.991875543062057	1
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	1/5114	15/18639	0.0666666666666667	0.242980054751662	0.991875543062057	1
GO:0005243	gap junction channel activity	2/5114	22/18639	0.0909090909090909	0.331336438297721	0.991989952363236	1
GO:0016651	oxidoreductase activity, acting on NAD(P)H	15/5114	88/18639	0.170454545454545	0.621255821808227	0.992038161959698	1
GO:0019843	rRNA binding	10/5114	65/18639	0.153846153846154	0.560723203273066	0.992785774304781	1
GO:0071855	neuropeptide receptor binding	5/5114	40/18639	0.125	0.455587602659366	0.993257662962741	1
GO:0005272	sodium channel activity	7/5114	51/18639	0.137254901960784	0.500253053900481	0.993969052632938	1
GO:0005324	long-chain fatty acid transmembrane transporter activity	1/5114	16/18639	0.0625	0.227793801329683	0.994106453327341	1
GO:0008391	arachidonate monooxygenase activity	1/5114	16/18639	0.0625	0.227793801329683	0.994106453327341	1
GO:0015399	primary active transmembrane transporter activity	32/5114	166/18639	0.192771084337349	0.702592929402396	0.994349408656162	1
GO:0008236	serine-type peptidase activity	38/5114	194/18639	0.195876288659794	0.713910470146636	0.995638788755613	1
GO:0005254	chloride channel activity	13/5114	83/18639	0.156626506024096	0.570856755139447	0.996181168685989	1
GO:0005372	water transmembrane transporter activity	1/5114	18/18639	0.0555555555555556	0.202483378959718	0.996898905396428	1
GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	1/5114	18/18639	0.0555555555555556	0.202483378959718	0.996898905396428	1
GO:0099094	ligand-gated monoatomic cation channel activity	24/5114	136/18639	0.176470588235294	0.643182497872047	0.997245073382807	1
GO:0008066	glutamate receptor activity	2/5114	26/18639	0.0769230769230769	0.280361601636533	0.997423014328434	1
GO:0099589	serotonin receptor activity	1/5114	19/18639	0.0526315789473684	0.19182635901447	0.997750578120915	1
GO:0042923	neuropeptide binding	3/5114	33/18639	0.0909090909090909	0.331336438297721	0.997761577402681	1
GO:0004364	glutathione transferase activity	2/5114	27/18639	0.0740740740740741	0.269977838612958	0.998065664458995	1
GO:0015252	proton channel activity	2/5114	27/18639	0.0740740740740741	0.269977838612958	0.998065664458995	1
GO:0022832	voltage-gated channel activity	32/5114	175/18639	0.182857142857143	0.666459578747416	0.99824606902848	1
GO:0019825	oxygen binding	3/5114	34/18639	0.0882352941176471	0.321591248936023	0.998283594565822	1
GO:0005242	inward rectifier potassium channel activity	2/5114	28/18639	0.0714285714285714	0.260335772948209	0.99854973175344	1
GO:0008527	taste receptor activity	2/5114	28/18639	0.0714285714285714	0.260335772948209	0.99854973175344	1
GO:0008227	G protein-coupled amine receptor activity	4/5114	41/18639	0.0975609756097561	0.355580567929262	0.998630348628919	1
GO:0036122	BMP binding	1/5114	21/18639	0.0476190476190476	0.173557181965473	0.998816532815119	1
GO:0015079	potassium ion transmembrane transporter activity	28/5114	160/18639	0.175	0.637822643723113	0.998833331668674	1
GO:0048019	receptor antagonist activity	2/5114	30/18639	0.0666666666666667	0.242980054751662	0.999187364827021	1
GO:0005244	voltage-gated monoatomic ion channel activity	30/5114	173/18639	0.173410404624277	0.632029044151722	0.999341387946805	1
GO:0016917	GABA receptor activity	1/5114	23/18639	0.0434782608695652	0.15846525309891	0.999377404191497	1
GO:0005184	neuropeptide hormone activity	2/5114	31/18639	0.0645161290322581	0.23514198846935	0.999392590827903	1
GO:0160041	neuropeptide activity	2/5114	32/18639	0.0625	0.227793801329683	0.999546398568919	1
GO:0015078	proton transmembrane transporter activity	32/5114	185/18639	0.172972972972973	0.630434736652961	0.999569275257433	1
GO:0004252	serine-type endopeptidase activity	30/5114	176/18639	0.170454545454545	0.621255821808227	0.999576708255085	1
GO:0005201	extracellular matrix structural constituent	28/5114	168/18639	0.166666666666667	0.607450136879155	0.999646797133925	1
GO:0022853	active monoatomic ion transmembrane transporter activity	17/5114	118/18639	0.144067796610169	0.525084016624355	0.999763261058682	1
GO:0003730	mRNA 3'-UTR binding	48/5114	262/18639	0.183206106870229	0.667731448172507	0.999795266941118	1
GO:0005267	potassium channel activity	18/5114	124/18639	0.145161290322581	0.529069474056039	0.9998049908594	1
GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	5/5114	56/18639	0.0892857142857143	0.325419716185262	0.999855935226996	1
GO:0051537	2 iron, 2 sulfur cluster binding	1/5114	28/18639	0.0357142857142857	0.130167886474105	0.999875067197702	1
GO:0022843	voltage-gated monoatomic cation channel activity	21/5114	143/18639	0.146853146853147	0.535235784942472	0.999909342683482	1
GO:0005249	voltage-gated potassium channel activity	12/5114	98/18639	0.122448979591837	0.446289896482645	0.999919953576173	1
GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	4/5114	53/18639	0.0754716981132075	0.275071760096221	0.999939506665282	1
GO:0099095	ligand-gated monoatomic anion channel activity	3/5114	47/18639	0.0638297872340425	0.232640477953719	0.99995151715038	1
GO:0017147	Wnt-protein binding	1/5114	31/18639	0.032258064516129	0.117570994234675	0.999952351133952	1
GO:0005230	extracellular ligand-gated monoatomic ion channel activity	7/5114	73/18639	0.0958904109589041	0.349491859574309	0.999957682064541	1
GO:0008188	neuropeptide receptor activity	3/5114	48/18639	0.0625	0.227793801329683	0.999963408358104	1
GO:0015020	glucuronosyltransferase activity	1/5114	34/18639	0.0294117647058824	0.107197082978674	0.999981830245609	1
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	4/5114	58/18639	0.0689655172413793	0.251358677329306	0.999984270348877	1
GO:0001653	peptide receptor activity	16/5114	128/18639	0.125	0.455587602659366	0.999987104282768	1
GO:0030280	structural constituent of skin epidermis	1/5114	37/18639	0.027027027027027	0.0985054276020252	0.999993072669436	1
GO:0009055	electron transfer activity	13/5114	116/18639	0.112068965517241	0.408457850660122	0.999994527296512	1
GO:0098960	postsynaptic neurotransmitter receptor activity	5/5114	69/18639	0.072463768115942	0.26410875516485	0.999995036895105	1
GO:0008528	G protein-coupled peptide receptor activity	14/5114	122/18639	0.114754098360656	0.418244356539746	0.999995123262961	1
GO:0022824	transmitter-gated monoatomic ion channel activity	4/5114	63/18639	0.0634920634920635	0.231409575953964	0.999995996175751	1
GO:0022835	transmitter-gated channel activity	4/5114	63/18639	0.0634920634920635	0.231409575953964	0.999995996175751	1
GO:0015276	ligand-gated monoatomic ion channel activity	26/5114	186/18639	0.139784946236559	0.509474308350259	0.999996642579385	1
GO:0022834	ligand-gated channel activity	26/5114	188/18639	0.138297872340426	0.504054368899725	0.999997673386126	1
GO:0003954	NADH dehydrogenase activity	1/5114	44/18639	0.0227272727272727	0.0828341095744303	0.99999927038225	1
GO:0005179	hormone activity	14/5114	132/18639	0.106060606060606	0.386559178014008	0.999999449365167	1
GO:0005261	monoatomic cation channel activity	56/5114	341/18639	0.164222873900293	0.598543243376528	0.999999523734891	1
GO:0022836	gated channel activity	49/5114	318/18639	0.154088050314465	0.561604843529785	0.99999989852711	1
GO:0005216	monoatomic ion channel activity	76/5114	448/18639	0.169642857142857	0.618297460751997	0.999999949802829	1
GO:0030594	neurotransmitter receptor activity	6/5114	97/18639	0.0618556701030928	0.225445411625254	0.999999983264218	1
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	1/5114	68/18639	0.0147058823529412	0.0535985414893372	0.999999999677544	1
GO:0030527	structural constituent of chromatin	2/5114	98/18639	0.0204081632653061	0.0743816494137741	0.999999999999221	1
GO:0003735	structural constituent of ribosome	7/5114	175/18639	0.04	0.145788032850997	1	1
GO:0030371	translation repressor activity	10/5114	329/18639	0.0303951367781155	0.110781179977961	1	1
GO:0045182	translation regulator activity	19/5114	356/18639	0.0533707865168539	0.194520549450067	1	1